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Prof Alex Gentle

STAFF PROFILE

Position

Deputy Head Of School

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Qualifications

Postgraduate Certificate in Ocular Therapeutics, University of Melbourne, 2011
Graduate Certificate in University Teaching, University of Melbourne, 2007
Doctor of Philosophy, University of Wales, 1999
Bachelor of Science, City University London, 1994

Contact

alex.gentle@deakin.edu.au
+61 3 522 72550

Affiliations

Fellow of the College of Optometrists

Fellow of the Australian College of Optometry

Fellow of the American Academy of Optometry

Member of the Association for Research in Vision and Ophthalmology

Publications

Filter by

2023

Myopia and Its Association with Near Work, Outdoor Time, and Housing Type among Schoolchildren in South India

Aparna Gopalakrishnan, Jameel Hussaindeen, Viswanathan Sivaraman, Meenakshi Swaminathan, Yee Wong, James Armitage, Alex Gentle, Simon Backhouse

(2023), Vol. 100, pp. 105-110, Optometry and Vision Science, C1

journal article

Clinical indicators for diabetic eyecare delivered by optometrists in Australia: a Delphi study

R Gyawali, M Toomey, F Stapleton, K Ho, L Keay, D Pye, P Katalinic, G Liew, Y Hsing, J Ramke, A Gentle, A Webber, K Schmid, S Bentley, P Hibbert, L Wiles, I Jalbert

(2023), pp. 1-10, Clinical and Experimental Optometry, London, Eng., C1

journal article
2022

Prevalence of myopia among urban and suburban school children in Tamil Nadu, South India: findings from the Sankara Nethralaya Tamil Nadu Essilor Myopia (STEM) Study

A Gopalakrishnan, J Hussaindeen, V Sivaraman, M Swaminathan, Y Wong, J Armitage, A Gentle, S Backhouse

(2022), Vol. 42, pp. 345-357, Ophthalmic and Physiological Optics, London, Eng., C1

journal article
2021

The sankara nethralaya tamil nadu essilor myopia (Stem) study-defining a threshold for non-cycloplegic myopia prevalence in children

A Gopalakrishnan, J Hussaindeen, V Sivaraman, M Swaminathan, Y Wong, J Armitage, A Gentle, S Backhouse

(2021), Vol. 10, pp. 1-10, Journal of Clinical Medicine, Switzerland, C1

journal article

Developing consensus-based referral criteria for low vision services in Australia

K Alam, H Connor, A Gentle, S Bentley

(2021), Vol. 42, pp. 149-160, Ophthalmic and Physiological Optics, Chichester, Eng., C1

journal article
2020

Multiple scan averaging to yield accurate quantitative analysis of optical coherence tomography angiograms

H Khan, A Gentle, J Armitage, C To, A Lam

(2020), Vol. 10, Scientific Reports, England, C1

journal article

Stakeholder acceptance of digital team-based learning

J Currey, S Sprogis, G Burdeu, I Story, J Considine, M O'Donnell, A Gentle, S Backhouse, E Oldland

(2020), Vol. 46, Nurse Education in Practice, Scotland, C1

journal article

Impact of axial eye size on retinal microvasculature density in the Macular region

M Khan, A Lam, J Armitage, L Hanna, C To, A Gentle

(2020), Vol. 9, pp. 1-15, Journal of Clinical Medicine, Switzerland, C1

journal article
2019

Implications of updating digital literacy - a case study in an optometric curriculum

J Coldwell-Neilson, J Armitage, R Wood-Bradley, B Kelly, A Gentle

(2019), Vol. 16, pp. 033-049, Issues in informing science and information technology, Santa Rosa, Calif., C1

journal article
2018

Scleral remodelling in myopia and its manipulation: a review of recent advances in scleral strengthening and myopia control

S Backhouse, A Gentle

(2018), Vol. 3, Annals of eye science, Hong Kong, C1

journal article
2017

Reduced scleral TIMP-2 expression is associated with myopia development: TIMP-2 supplementation stabilizes scleral biomarkers of myopia and limits myopia development

H Liu, M Kenning, A Jobling, N McBrien, A Gentle

(2017), Vol. 58, pp. 1971-1981, Investigative Ophthalmology and Visual Science, United States, C1

journal article
2011

The M4 muscarinic antagonist MT-3 inhibits myopia in chick: evidence for site of action

N McBrien, B Arumugam, A Gentle, A Chow, S Sahebjada

(2011), Vol. 31, pp. 529-539, Ophthalmic & physiological optics, Oxford, Eng., C1-1

journal article

Myopia : why study the mechanisms of myopia? Novel approaches to risk factors Signaling eye growth- how could basic biology be translated into clinical insights? Where are genetic and proteomic approaches leading? How does visual function contribute to and interact with ametropia? Does eye shape matter? Why ametropia at all?

E Tarutta, W Chua, T Young, E Goldschmidt, S Saw, K Rose, E Smith, D Mutti, R Ashby, R Stone, C Wildsoet, H Howland, A Fischer, W Stell, A Reichenbach, M Frost, A Gentle, X Zhu, J Summers-Rada, V Barathi, L Jiang, S McFadden, J Guggenheim, C Hammond, R Schippert, C To, J Gwiazda, S Marcos, M Collins, W Charman, P Artal, J Tabernero, D Atchison, A Seidemann, D Uttenweiler, D Troilo, T Norton, J Wallman

(2011), Vol. 88, pp. 404-447, Optometry and vision science, Sydney, N.S.W., C1-1

journal article
2010

Inhibition of matrix metalloproteinase activity in the chick sclera and its effect on myopia development

H Liu, A Gentle, A Jobling, N McBrien

(2010), Vol. 51, pp. 2865-2871, Investigative ophthalmology & visual science, Rockville, Md., C1-1

journal article
2009

Expression of muscarinic receptor subtypes in tree shrew ocular tissues and their regulation during the development of myopia

N McBrien, A Jobling, H Truong, C Cottriall, A Gentle

(2009), Vol. 15, pp. 464-475, Molecular vision: Biology and genetics in vision research, Atlanta, Ga., C1-1

journal article

Biomechanics of the sclera in myopia: Extracellular and cellular factors

N McBrien, A Jobling, A Gentle

(2009), Vol. 86, pp. 23-30, Optometry and vision science, Sydney, N.S.W., C1-1

journal article

Myopia: Recent advances in molecular studies; Prevalence, progression and risk factors; Emmetropization; Therapies; Optical links; Peripheral refraction; Sclera and ocular growth; Signalling cascades; and animal models.

N McBrien, T Young, C Pang, C Hammond, P Baird, S Saw, I Morgan, D Mutti, K Rose, J Wallman, A Gentle, C Wildsoet, J Gwiazda, K Schmid, E Smith, D Troilo, J Summers-Rada, T Norton, F Schaeffel, P Megaw, R Beuerman, S McFadden

(2009), Vol. 86, pp. 45-66, Optometry and vision science, Sydney, N.S.W., C1-1

journal article

Retinal and choroidal TGF-β in the tree shrew model of myopia: Isoform expression, activation and effects on function

A Jobling, R Wan, A Gentle, B Bui, N McBrien

(2009), Vol. 88, pp. 458-466, Experimental eye research, Amsterdam, The Netherlands, C1-1

journal article
2008

Regulation of scleral cell contraction by transforming growth factor-β and stress competing roles in myopic growth

A Jobling, A Gentle, R Metlapally, B McGowan, N McBrien

(2008), Vol. 284, pp. 2072-2079, Journal of biological chemistry, Manchester, Eng., C1-1

journal article
2006

Altered visual sensitivity in axial high myopia: a local postreceptoral phenomenon?

A Jaworski, A Gentle, A Zele, A Vingrys, N McBrien

(2006), Vol. 47, pp. 3695-3702, Investigative ophthalmology and visual science, Rockville, Md., C1-1

journal article

Characterization of the integrin receptor subunit profile in the mammalian sclera

R Metlapally, A Jobling, A Gentle, N McBrien

(2006), Vol. 12, pp. 725-734, Molecular vision, Atlanta, Ga., C1-1

journal article

Expression of collagen-binding integrin receptors in the mammalian sclera and their regulation during the development of myopia

N McBrien, R Metlapally, A Jobling, A Gentle

(2006), Vol. 47, pp. 4674-4682, Investigative ophthalmology and visual science, Rockville, Md., C1-1

journal article
2004

Muscarinic antagonist control of myopia: A molecular search for the M1 receptor in chick

G Yin, A Gentle, N McBrien

(2004), Vol. 10, pp. 787-793, Molecular Vision, C1-1

journal article

Isoform-specific changes in scleral transforming growth factor-beta expression and the regulation of collagen synthesis during myopia progression

A Jobling, M Nguyen, A Gentle, N McBrien

(2004), Vol. 279, pp. 18121-18126, Journal of biological chemistry, Rockville, Md., C1-1

journal article
2003

Role of the sclera in the development and pathological complications of myopia

N McBrien, A Gentle

(2003), Vol. 22, pp. 307-338, Progress in retinal and eye research, Kidlington, Eng., C1-1

journal article

Collagen gene expression and the altered accumulation of scleral collagen during the development of high myopia

A Gentle, Y Liu, J Martin, G Conti, N McBrien

(2003), Vol. 278, pp. 16587-16594, Journal of biological chemistry, Bethesda, Md., C1-1

journal article
2002

Retinoscleral control of scleral remodelling in refractive development: a role for endogenous FGF-2?

A Gentle, N McBrien

(2002), Vol. 18, pp. 344-348, Cytokine, Amsterdam, The Netherlands, C1-1

journal article

Pirenzepine affects scleral metabolic changes in myopia through a non-toxic mechanism

H-T Truong, C Cottriall, A Gentle, N McBrien

(2002), Vol. 74, pp. 103-111, Experimental eye research, Amsterdam, The Netherlands, C1-1

journal article
2001

Glycosaminoglycan synthesis in the separate layers of the chick sclera during myopic eye growth: comparison with mammals

A Gentle, H Truong, N McBrien

(2001), Vol. 23, pp. 179-184, Current eye research, Abingdon, Eng., C1-1

journal article

High-resolution semi-quantitative real-time PCR without the use of a standard curve

A Gentle, F Anastasopoulos, N McBrien

(2001), Vol. 31, pp. 502-508, Biotechniques, Boca Raton, Fla., C1-1

journal article

Structural and ultrastructural changes to the sclera in a mammalian model of high myopia

N McBrien, L Cornell, A Gentle

(2001), Vol. 42, pp. 2179-2187, Investigative ophthalmology & visual science, Rockville, Md., C1-1

journal article

The role of visual information in the control of scleral matrix biology in myopia

N McBrien, A Gentle

(2001), Vol. 23, pp. 313-319, Current eye research, Abingdon, Eng., C1-1

journal article
2000

Scleral remodeling during the development of and recovery from axial myopia in the tree shrew

N McBrien, P Lawlor, A Gentle

(2000), Vol. 41, pp. 3713-3719, Investigative opthalmology & visual science, Rockville, Md., C1-1

journal article
1999

Modulation of scleral DNA synthesis in development of and recovery from induced axial myopia in the tree shrew

A Gentle, N McBrien

(1999), Vol. 68, pp. 155-163, Experimental eye research, London, Eng., C1-1

journal article

Optical correction of induced axial myopia in the tree shrew: implications for emmetropization

N McBrien, A Gentle, C Cottriall

(1999), Vol. 76, pp. 419-427, Optometry and vision science, Orlando, Fla., C1-1

journal article

Funded Projects at Deakin

No Funded Projects at Deakin found

Supervisions

Principal Supervisor
2022

Khyber Alam

Thesis entitled: Increasing Access to Low Vision Rehabilitation Services in Australia

Doctor of Philosophy (Medicine), School of Medicine

Associate Supervisor
2023

Aparna Gopalakrishnan

Thesis entitled: Myopia Prevalence, Risk Factors and Ocular Growth among Children in South India

Doctor of Philosophy (Medicine), School of Medicine

Hugh Gillies

Thesis entitled: Remote Follow-Up of Hip and Knee Arthroplasty Patients: A New Model of Care

Master of Surgical Research, School of Medicine