Profile image of Alister Ward

Prof Alister Ward

STAFF PROFILE

Position

Associate Head Of School (Research)

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Qualifications

Bachelor of Science, University of Melbourne, 1989
Doctor of Philosophy, University of Melbourne, 1994
Bachelor of Arts, University of Melbourne, 2001

Contact

alister.ward@deakin.edu.au
+61 3 522 72041

Research interests

The immune system is vital for maintaining good health. However, much remains to be learnt about how it develops normally, how it is perturbed in disease and how it is subverted during infection. One key facet of the immune system are the various cytokines and their receptors that regulate it. Prof. Ward leads a research team at Deakin University’s new Medical School investigating the genes involved in the development of the immune system, including cytokine receptor signalling components, with the aim of understanding their function, evolution, and role in disease. This research utilises multi-disciplinary approach, combining bioinformatics, molecular biology and functional genomics approaches in the zebrafish model.
Prof. Ward’s group is housed in the $15M Molecular Medicine Research Facility, which opened in April 2011 and contains a comprehensive suite of equipment to service molecular biology, cell biology, microscopy and histology at PC2 level. CI-Ward also oversees the ARC LIEF-funded FishWorks facility, which consists of an extensive Aquatic Habitats aquarium with a 700-tank capacity, including breeding tanks, independent light cycles, and nursery, as well as an exquisite range of equipment for zebrafish embryo manipulation and analysis, including dedicated microinjectors, fluorescence microscopes and digital cameras, and currrenlty being further upgraded.

Teaching interests

Prof. Ward has significant teaching expertise, previously serving as Year 1 & 2 Co-ordinator for Medicine and Course Director for Biomedical Science. He currently teaches into ‘Human Biology’ and ‘Infection, Defence & Repair’ in the Medical Course and ‘Immunology & Hematology’ in Biomedical Sciences, and contributes to the supervision of 3rd year, Intern, Honours and PhD students.

Knowledge areas

Prof. Ward was awarded a Bachelor of Science (Honours), Bachelor of Arts and Doctor of Philosophy from the University of Melbourne, and has then trained as a European Molecular Biology Organisation Long-Term Fellow and a Sylvia and Charles Viertel Senior Medical Research Fellow. This has provided him with significant expertise in biochemistry, genetics, functional genomics, bioinformatics, immunology, haematology and developmental biology.

Professional activities

CI-Ward has a strong presence in the local, national and international research community, illustrated by the following specific activities:

> Conference Organisation:
• 8th Australian & New Zealand Zebrafish Workshop, Geelong, Australia (2007)
- Organising Committee (Chair)
• Infection & Immunity Conference, Gold Coast, Australia (2009)
- Scientific Advisory Committee
• Emerging Infectious Diseases Conference, Geelong, Australia (2012)
- Scientific Advisory Committee
• 4th International One Health Conference, Melbourne, Australia (2016)
- Organising Committee

> Grant Review:
• Australian Research Council
- International Reader (2004-)
- College of Experts Member (2013-)
• National Health & Medical Research Council
- Project Grant Reviewer (2001-)
- Grant Review Panel Member (2011)

> Editorial Roles:
• Frontiers in Bioscience, Special Issue: ‘Granulocyte colony-stimulating factor and its receptor: roles in health and disease’
- Managing Editor (2007)
• JAK-STAT
- Editorial Board Member (2012-)
• American Journal of Experimental and Clinical Immunology
- Editorial Board Member (2012-)
• Journal of Blood Diseases
- Editorial Board Member (2014-)

> Other Peer Review, etc:
• Regular manuscripts from >15 journals, including Blood, Haematologica, and J Immunol
• Judging panels, including ASMR Vic. Premier’s Award (2006-11,14), SMART Geelong Awards (2010,12-13)
• Regular theses (1-2/year)

> Research Training:
• BSc(Hons):
- 10 completed (9 with H1 – 3 top of cohort, 9 continued to PhD)
• PhD:
- 9 completed (4 prize-winners, all continued to postdoc/faculty roles, incl. at WEHI, Peter MacCallum Cancer Institute, University College London)
- 9 current

> Leadership/Representative Roles:
• Australian Society for Biochemistry & Molecular Biology
- Review Panellist (2004)
• Australian Society for Medical Research
- Medical Research Week Committee (2000-5)
- Careers Sub-Committee (2000-4)
- Assistant to the Premier’s Award (2002-5)
- Premier’s Award Sub-Committee (2004-5), Chair (2004-5)
• BioGeelong
- Steering Committee Chair (2008-10)
• Geelong Centre for Emerging Infectious Diseases
- Steering Committee (2009-)
• Biosciences Victoria
- Deakin University rep (2010-2)
• Victorian Technology Network
- Deakin University rep (2010-)
• Research Australia
- Deakin University rep (2011)

Awards

Consistently successful at obtaining competitive funding, Professor Ward has been awarded funds totalling in excess of $4.2 million, with the majority from National Competitive Grant Schemes. He has also received a number of prestigious fellowships, including a European Molecular Biology Organisation Long-Term Fellowship, an AMRAD Postdoctoral Award and a Sylvia and Charles Viertel Senior Medical Research Fellowship. In the last 10 years these include:
• Australian Research Council Discovery Project Grant, ‘Socs proteins in health and disease’, 2005-2007 $215 000 (CI: AC Ward)
• Australian & Pacific Science Foundation Grant, ‘Impact of subterranean water on the physiology and health of Murray Cod (Maccullochella peeli peeli)’, 2006-2008 $28 000 (CIs: P Jones, S De Silva, G Turchini, T Toop, AC Ward)
• Geelong Community Foundation Grant, ‘Establishment of medical school’, 2007 $30 000 (CIs: W Duan, B Crotty, AC Ward)
• National Health & Medical Research Council Enabling Grant, ‘Australian zebrafish phenomics facility’, 2007-2011 $1 500 000 (CIs: A Perkins, B Key, J Rothnagel, A Ward, S Grimmond, P Alewood, D Hume, A Boyd, M Lardelli)
• Geelong Community Foundation, ‘Establishment of GTRAC’, 2009 $47 000 (CI: AC Ward)
• The Foundation for Children, ‘Defining mechanisms underlying skeletal muscle development and muscular dystrophy’, 2010-2012 $157 000 (CIs: D McCulloch, N Stupka, AC Ward)
• Collier Charitable Fund, ‘Study of embryonic development: automatic gene detection device’, 2012 $48 000 (CIs: Y Gibert, AC Ward)
• Australian Research Council Linkage Infrastructure Equipment Fund Grant, ‘Collaborative high bio-containment immunological research facility’, 2012 $520 000 (CIs: AC Ward, J Mak, LF Wang, J Stambas, J Lowenthal, R Tripp, TF de Koning-Ward, WA Buttemer)
• Atkins Charitable Trust, ‘Role of cytokine receptors in ovarian cancer’, 2012-2015 $42 500 (CIs: AC Ward, W Duan, D McCulloch)

Publications

Filter by

2017

The extracellular matrix in cancer progression: role of hyalectan proteoglycans and ADAMTS enzymes

M Binder, S McCoombe, E Williams, D McCulloch, A Ward

(2017), Vol. 385, pp. 55-64, Cancer letters, C1

journal

Vitamin D insufficiency in the first 6 months of infancy and challenge-proven IgE-mediated food allergy at 1 year of age: a case-cohort study

J Molloy, J Koplin, K Allen, M Tang, F Collier, J Carlin, R Saffery, D Burgner, S Ranganathan, T Dwyer, A Ward, M Moreno-Betancur, M Clarke, A Ponsonby, P Vuillermin

(2017), pp. 1-10, Allergy, C1

journal

shRNAs targeting either the glycoprotein or polymerase genes inhibit viral haemorrhagic septicaemia virus replication in zebrafish ZF4 cells

B Clarke, K McColl, A Ward, T Doran

(2017), Vol. 141, pp. 124-132, Antiviral research, C1

journal
2016

Conserved IL-2R?c Signaling Mediates Lymphopoiesis in Zebrafish

R Sertori, C Liongue, F Basheer, K Lewis, P Rasighaemi, D de Coninck, D Traver, A Ward

(2016), Vol. 196, pp. 135-143, Journal of immunology, C1

journal

Signaling via the CytoR/JAK/STAT/SOCS pathway: emergence during evolution

C Liongue, T Taznin, A Ward

(2016), Vol. 71, pp. 166-175, Molecular immunology, C1

journal

Evolution of cytokine receptor signaling.

C Liongue, R Sertori, A Ward

(2016), Vol. 197, pp. 11-18, Journal of immunology, C1

journal

The ADAMTS hyalectanase family: biological insights from diverse species

C Dancevic, D McCulloch, A Ward

(2016), Vol. 473, pp. 2011-2022, Biochemical journal, C1

journal

Genome editing in zebrafish: a practical overview

R Sertori, M Trengove, F Basheer, A Ward, C Liongue

(2016), Vol. 15, pp. 322-330, Briefings in functional genomics, C1

journal
2015

ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish

P Rasighaemi, S Onnebo, C Liongue, A Ward

(2015), Vol. 100, pp. 23-31, Haematologica, C1

journal

Characterisation of chicken viperin

K Goossens, A Karpala, A Rohringer, A Ward, A Bean

(2015), Vol. 63, pp. 373-380, Molecular immunology, C1

journal

G-CSF treatment can attenuate dexamethasone-induced reduction in C2C12 myotube protein synthesis

C Wright, E Brown, A Ward, A Russell

(2015), Vol. 73, pp. 1-7, Cytokine, C1

journal

The evolutionary conservation of the A Disintegrin-like and Metalloproteinase domain with Thrombospondin-1 motif metzincins across vertebrate species and their expression in teleost zebrafish

F Brunet, F Fraser, M Binder, A Smith, C Kintakas, C Dancevic, A Ward, D McCulloch

(2015), Vol. 15, pp. 1-15, BMC evolutionary biology, C1

journal

Functional analysis of truncated forms of ETV6

P Rasighaemi, C Liongue, S Onnebo, A Ward

(2015), Vol. 171, pp. 658-662, British journal of haematology, C1

journal

Zebrafish as a model for leukemia and other hematopoietic disorders

P Rasighaemi, F Basheer, C Liongue, A Ward

(2015), Vol. 8, pp. 1-10, Journal of hematology & oncology, C1

journal

Is low vitamin D status a risk factor for food allergy? Current evidence and future directions

J Molloy, A Ponsonby, K Allen, M Tang, F Collier, A Ward, J Koplin, P Vuillermin

(2015), Vol. 15, pp. 944-952, Mini-reviews in medicinal chemistry, C1

journal

Lipid abundance in zebrafish embryos is regulated by complementary actions of the endocannabinoid system and retinoic acid pathway

D Fraher, M Ellis, S Morrison, S McGee, A Ward, K Walder, Y Gibert

(2015), Vol. 156, pp. 3596-3609, Endocrinology, C1

journal

EpCAM aptamer-mediated survivin silencing sensitized cancer stem cells to doxorubicin in a breast cancer model

T Wang, M Gantier, D Xiang, A Bean, M Bruce, S Zhou, M Khasraw, A Ward, L Wang, M Wei, H AlShamaileh, L Chen, X She, J Lin, L Kong, S Shigdar, W Duan

(2015), Vol. 5, pp. 1456-1472, Theranostics, C1

journal

Cytokine networks and cancer stem cells

C Liongue, A Ward, W Duan, S Shigdar

(2015), pp. 67-87, Cancer stem cells : emerging concepts and future perspectives in translational oncology, Berlin, Germany, B1

chapter
2014

Granulocyte colony-stimulating factor receptor signalling via Janus kinase 2/signal transducer and activator of transcription 3 in ovarian cancer

J Kumar, F Fraser, C Riley, N Ahmed, D McCulloch, A Ward

(2014), Vol. 110, pp. 133-145, British Journal of Cancer, C1

journal

Regulation of embryonic hematopoiesis by a cytokine-inducible SH2 domain homolog in zebrafish.

R Lewis, S Noor, F Fraser, R Sertori, C Liongue, A Ward

(2014), Vol. 192, pp. 5739-5748, Journal of immunology, C1

journal

Role of the interleukin 6 receptor family in epithelial ovarian cancer and its clinical implications.

J Kumar, A Ward

(2014), Vol. 1845, pp. 117-125, Biochimica et biophysica acta, C1

journal

G-CSF does not influence C2C12 myogenesis despite receptor expression in healthy and dystrophic skeletal muscle

C Wright, E Brown, P Della-Gatta, A Ward, G Lynch, A Russell

(2014), Vol. 5, pp. 1-13, Frontiers in physiology, C1

journal

Granulocyte colony-stimulating factor receptor mutations in myeloid malignancy

C Liongue, A Ward

(2014), Vol. 4, pp. 1-7, Frontiers in oncology, C1

journal

Characterisation of chicken ZAP

K Goossens, A Karpala, A Ward, A Bean

(2014), Vol. 46, pp. 373-381, Developmental & comparative immunology, C1

journal

Cytokine receptor signaling in teleosts

A Ward, R Sertori, C Liongue

(2014), pp. 39-72, Teleosts: evolutionary development, diversity and behavioral ecology, New York, N.Y., B1

chapter

ETV6 (TEL1) in blood cell development and malignancy

P Rasighaemi, C Liongue, A Ward

(2014), Vol. 1, pp. 1-7, Journal of blood disorders, C1

journal
2013

Zebrafish as a genetic model in pre-clinical drug testing and screening

Y Gibert, M Trengove, A Ward

(2013), Vol. 20, pp. 2458-2466, Current Medicinal Chemistry, C1

journal

Metabolic profile analysis of zebrafish embryos

Y Gibert, S McGee, A Ward

(2013), Vol. 71, pp. 1-5, Journal of visualized experiments, C1

journal

Chicken interferons, their receptors and interferon-stimulated genes

K Goossens, A Ward, J Lowenthal, A Bean

(2013), Vol. 41, pp. 370-376, Developmental and Comparative Immunology, C1

journal

Pegasus, the 'atypical' Ikaros family member, influences left-right asymmetry and regulates pitx2 expression

L John, M Trengove, F Fraser, S Yoong, A Ward

(2013), Vol. 377, pp. 46-54, Developmental Biology, C1

journal

Versican processing by a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats proteinases-5 and -15 facilitates myoblast fusion

N Stupka, C Kintakas, J White, F Fraser, M Hanciu, N Aramaki-Hattori, S Martin, C Coles, F Collier, A Ward, S Apte, D McCulloch

(2013), Vol. 288, pp. 1907-1917, Journal of biological chemistry, C1

journal

Evolution of the JAK-STAT pathway

C Liongue, A Ward

(2013), Vol. 2, JAK-STAT, C1

journal

Characterization of zebrafish polymerase iii promoters for the expression of short hairpin RNA interference molecules

B Clarke, D Cummins, K McColl, A Ward, T Doran

(2013), Vol. 10, pp. 472-479, Zebrafish, C1

journal

The potential link between gut microbiota and IgE-mediated food allergy in early life

J Molloy, K Allen, F Collier, M Tang, A Ward, P Vuillermin

(2013), Vol. 10, pp. 7235-7256, International journal of environmental research and public health, C1

journal

SOCS proteins in development and disease

M Trengove, A Ward

(2013), Vol. 2, pp. 1-29, American journal of clinical and experimental immunology, C1

journal

Biosynthesis and expression of a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats-15

C Dancevic, F Fraser, A Smith, N Stupka, A Ward, D McCulloch

(2013), Vol. 288, pp. 37267-37276, Journal of Biological Chemistry, C1

journal
2012

Evolution of JAK-STAT pathway components : mechanisms and role in immune system development

C Liongue, L O'Sullivan, M Trengove, A Ward

(2012), Vol. 7, pp. 1-16, PLoS one, C1

journal

Koi herpesvirus encodes and expresses a functional interleukin-10

A Sunarto, C Liongue, K McColl, M Adams, D Bulach, M Crane, K Schat, B Slobedman, A Barnes, A Ward, P Walker

(2012), Vol. 86, pp. 11512-11520, Journal of virology, C1

journal

Alternative TEL-JAK2 fusions associated with T-cell acute lymphoblastic leukemia and atypical chronic myelogenous leukemia dissected in zebrafish

S Onnebo, P Rasighaemi, J Kumar, C Liongue, A Ward

(2012), Vol. 97, pp. 1895-1903, Haematologica, C1

journal

Systematic investigation of oxygen and growth factors in clinically valid ex vivo expansion of cord blood CD34+ hematopoietic progenitor cells

M Tursky, F Collier, A Ward, M Kirkland

(2012), Vol. 14, pp. 679-685, Cytotherapy, C1

journal
2011

Groundwater pre-treatment prevents the onset of chronic ulcerative dermatopathy in juvenile Murray cod, Maccullochella peelii peelii (Mitchell)

A Schultz, S Shigdar, P Jones, A Ward, T Toop

(2011), Vol. 312, pp. 19-25, Aquaculture, C1

journal

Suppressor of cytokine signaling 1 regulates embryonic myelopoiesis independently of its effects on T cell development

L O'Sullivan, S Noor, M Trengove, R Lewis, C Liongue, N Sprigg, S Nicholson, A Ward

(2011), Vol. 186, pp. 4751-4761, Journal of immunology, C1

journal

Clinical applications of aptamers and nucleic acid therapeutics in haematological malignancies

S Shigdar, A Ward, A De, C Yang, M Wei, W Duan

(2011), Vol. 155, pp. 3-13, British journal of haematology, C1

journal

Shooting the messenger : targeting signal transduction pathways in leukemia and related disorders

S Noor, R Bell, A Ward

(2011), Vol. 78, pp. 33-44, Critical reviews in oncology / hematology, C1

journal

The Ikaros gene family : transcriptional regulators of hematopoiesis and immunity

L John, A Ward

(2011), Vol. 48, pp. 1272-1278, Molecular immunology, C1

journal

Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile

A Latifi, K Abubaker, N Castrechini, A Ward, C Liongue, F Dobill, J Kumar, E Thompson, M Quinn, J Findlay, N Ahmed

(2011), Vol. 112, pp. 2850-2864, Journal of cellular biochemistry, C1

journal

Origins of adaptive immunity

C Liongue, L John, A Ward

(2011), Vol. 31, pp. 61-71, Critical reviews in immunology, C1

journal
2009

Multiple mini-interview : how long is long enough?

M Dodson, B Crotty, D Prideaux, R Carne, A Ward, E de Leeuw

(2009), Vol. 43, pp. 168-174, Medical education, C1

journal

Genetic and molecular diagnosis of severe congenital neutropenia

A Ward, D Dale

(2009), Vol. 16, pp. 9-13, Current opinion in hematology, C1

journal

Cytochemical characterisation of the leucocytes and thrombocytes from murray cod (Maccullochella peelii peelii, Mitchell)

S Shigdar, A Harford, A Ward

(2009), Vol. 26, pp. 731-736, Fish and shellfish immunology, C1

journal

Suppressors of cytokine signaling : functions in normal biology and roles in disease

A Ward, A Barry, L O'Sullivan

(2009), pp. 10-23, Jak-stat pathway in disease, Austin, Tex., B1

chapter

Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial?mesenchymal transition in ovarian carcinomas

M Colomiere, A Ward, C Riley, M Trenerry, D Cameron-Smith, J Findlay, L Ackland, N Ahmed

(2009), Vol. 100, pp. 134-144, British journal of cancer, C1

journal

Granulocyte colony-stimulating factor receptor: stimulating granulopoiesis and much more

C Liongue, C Wright, A Russell, A Ward

(2009), Vol. 41, pp. 2372-2375, International journal of biochemistry and cell biology, C1

journal

A novel zebrafish jak2a V581F model shared features of human JAK2 V617F polycythemia vera

A Ma, A Fan, A Ward, C Liongue, R Lewis, S Cheng, P Chan, S Yip, R Liang, A Leung

(2009), Vol. 37, pp. 1379-1386, Experimental hematology, C1

journal

Altering presenilin gene activity in zebrafish embryos causes changes in expression of genes with potential involvement in alzheimer's disease pathogenesis

M Newman, B Tucker, S Nornes, A Ward, M Lardelli

(2009), Vol. 16, pp. 133-147, Journal of alzheimer's disease, C1-1

journal

Zebrafish granulocyte colony-stimulatingZebrafish granulocyte colony-stimulating factor receptor signaling promotes myelopoiesis and myeloid cell migration

C Liongue, C Hall, B O'Connell, P Crosier, A Ward

(2009), Vol. 113, pp. 2535-2546, Blood, C1

journal

Evolution of the ikaros gene family : implications for the origins of adaptive immunity

L John, S Yoong, A Ward

(2009), Vol. 182, pp. 4792-4799, The journal of immunology, C1

journal
2008

Functional interaction between mutations in the granulocyte colony-stimulating factor receptor in severe congenital neutropenia

A Ward, J Gits, F Majeed, A Aprikyan, R Lewis, L O`Sullivan, M Freedman, S Shigdar, I Touw, D Dale, Y Dror

(2008), Vol. 142, pp. 653-656, British journal of haematology, C1

journal

Exercise-induced activation of STAT3 signaling is increased with age

M Trenerry, K Carey, A Ward, M Farnfield, D Cameron-Smith

(2008), Vol. 11, pp. 717-724, Rejuvenation research, C1

journal

Stat5 as a diagnostic marker for leukemia

R Lewis, A Ward

(2008), Vol. 8, pp. 73-82, Expert review of molecular diagnostics, C1

journal
2007

Evolution of class I cytokine receptors

C Liongue, A Ward

(2007), Vol. 7, pp. 1-15, BMC evolutionary biology, C1

journal

From transcriptome to biological function: environmental stress in an ectothermic vertebrate, the coral reef fish Pomacentrus moluccensis

K Kassahn, R Crozier, A Ward, G Stone, M Caley

(2007), Vol. 8, pp. 1-16, BMC Genomics, C1

journal

The role of jak2a in zebrafish hematopoiesis

A Ma, A Ward, R Liang, A Leung

(2007), Vol. 110, pp. 1824-1830, Blood, C1

journal

Heterologous microarray experiments used to identify the early gene response to heat stress in a coral reef fish

K Kassahn, M Caley, A Ward, A Connolly, G Stone, R Crozier

(2007), Vol. 16, pp. 1749-1763, Molecular ecology, C1

journal

Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease

L O`Sullivan, C Liongue, R Lewis, S Stephenson, A Ward

(2007), Vol. 44, pp. 2497-2506, Molecular immunology, C1

journal

Blood cells of Murray cod maccullochella peelii peelii (Mitchell)

S Shigdar, D Cook, P Jones, A Harford, A Ward

(2007), Vol. 70, pp. 973-980, Journal of fish biology, C1

journal

The role of the granulocyte colony-stimulating factor receptor (G-CSF-R) in disease

A Ward

(2007), Vol. 12, pp. 608-618, Frontiers in bioscience, C1

journal

Characterization of the zebrafish matrix metalloproteinase 9 gene and its developmental expression pattern

S Yoong, B O'Connell, A Soanes, M Crowhurst, G Lieschke, A Ward

(2007), Vol. 7, pp. 39-46, Gene expression patterns, C1

journal

The myeloproliferative disorder-associated JAK2 V617F mutant escapes negative regulation by suppressor of cytokine signaling 3

M Hookham, J Elliott, Y Suessmuth, J Staerk, A Ward, W Vainchenker, M Percy, M McMullin, S Constantinescu, J Johnston

(2007), Vol. 109, pp. 4924-4929, Blood, C1

journal

STAT3 signaling is activated in human skeletal muscle following acute resistance exercise

M Trenerry, K Carey, A Ward, D Cameron-Smith

(2007), Vol. 102, pp. 1483-1489, Journal of applied physiology, C1

journal
2006

Constitutive activation of zebrafish Stat5 expands hematopoietic cell populations in vivo

R Lewis, S Stephenson, A Ward

(2006), Vol. 34, pp. 179-187, Experimental hematology, C1

journal

Multiple pathways contribute to the hyperproliferative responses from truncated granulocyte colony-stimulating factor receptors

J Gits, D van Leeuwen, H Carroll, I Touw, A Ward

(2006), Vol. 20, pp. 2111-2118, Leukemia, C1

journal
2005

Hematopoietic perturbation in zebrafish expressing a tel-jak2a fusion

S Onnebo, M Condron, D McPhee, G Lieschke, A Ward

(2005), Vol. 33, pp. 182-188, Experimental hematology, C1

journal

RBMX gene is essential for brain development in Zebrafish

E Tsend-Ayush, L O`Sullivan, F Grutzner, S Onnebo, R Lewis, M Delbridge, J Marshall Graves, A Ward

(2005), Vol. 234, pp. 682-688, Developmental dynamics, C1

journal
2004

Conservation, duplication and divergence of the zebrafish stat5 genes

R Lewis, A Ward

(2004), Vol. 338, pp. 65-74, Gene, C1

journal

Harnessing zebrafish for the study of white blood cell development and its perturbation

S Onnebo, S Yoong, A Ward

(2004), Vol. 32, pp. 789-796, Experimental hematology, C1

journal

Receptor activation and 2 distinct COOH- terminal motifs control G-CSF receptor distribution and internalization kinetics.

L Aarts, O Roovers, A Ward, I Touw

(2004), Vol. 103, pp. 571-579, Blood, C1-1

journal
2003

The zebrafish spil promoter drives myeloid-specific expression in stable transgenic fish

A Ward, D McPhee, M Condron, S Varma, S Cody, S Onnebo, B Paw, L Zon, G Lieschke

(2003), Vol. 102, pp. 3238-3240, Blood, C1

journal

Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells

M Hermans, G van de Geijn, C Antonissen, J Gits, D van Leeuwen, A Ward, I Touw

(2003), Vol. 101, pp. 2584-2590, Blood, C1

journal
2002

Stats and hematopoiesis

A Ward

(2002), pp. 78-91, Jak-stat pathway in hematopoiesis and disease, Georgetown, Tex., B1

chapter

The zebrafish as a model system for human disease

A Ward, G Lieschke

(2002), Vol. 7, Frontiers in bioscience, C1-1

journal

Specificity and affinity motifs for Grb2 SH2-ligand interactions

H Kessels, A Ward, T Schumacher

(2002), Vol. 99, pp. 8524-8529, Proceedings of the National Academy of Sciences, C1-1

journal

Tyrosine residues of the granulocyte colony-stimulating factor transmit proliferation and differentiation signals in murine bone marrow cells

S Arkbarzadeh, A Ward, D McPhee, W Alexander, G Lieschke, J Layton

(2002), Vol. 99, pp. 879-887, Blood, C1-1

journal

G-CSF: function and modes of action (Review)

S Basu, A Dunn, A Ward

(2002), Vol. 10, pp. 3-10, International journal of molecular medicine, C1-1

journal

Zebrafish SPI-1 marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning.

G Lieschke, A Oates, B Paw, M Thompson, N Hall, A Ward, R Ho, L Zon, J Layton

(2002), Vol. 246, pp. 274-295, Developmental biology, C1-1

journal
2001

Proteomic analysis of macrophage differentiation

X Csar, N Wilson, K McMahon, D Marks, T Beecroft, A Ward, G Whitty, V Kanangasundarum, J Hamilton

(2001), Vol. 276, pp. 26211-26217, Journal of Biological Chemistry, C1-1

journal

C/EBPÁ and G-CSF receptor signals cooperate to induce the myeloperoxidase and neutrophil elastase genes

W Wang, X Wang, A Ward, I Touw, A Friedman

(2001), Vol. 15, pp. 779-786, Leukemia, C1-1

journal

Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish.

G Lieschke, A Oates, M Crowhurst, A Ward, J Layton

(2001), Vol. 98, pp. 3087-3096, Blood, C1-1

journal

Copper/zinc superoxide dismutase is phosphorylated and modulated specifically by granulocyte-colony stimulating factor in myeloid cells.

X Csar, N Wilson, P Strike, L Sparrow, K McMahon, A Ward, J Hamilton

(2001), Vol. 1, pp. 435-443, Proteomics, C1-1

journal

Somatostatin modulates G-CSF-induced but not interleukin-3-induced proliferative responses in myeloid 32D cells via activation of somatostatin receptor subtype 2

S Oomen, A Ward, L Hofland, S Lamberts, B Löwenberg, I Touw

(2001), Vol. 2, pp. 322-329, Hematology journal: the official journal of the European haematology association / EHA, C1-1

journal

Grants

Australian Competitive Grants

Defining mechanisms underlying skeletal muscle development and muscular dystrophy

Dr Daniel Mcculloch, Dr Nicole Stupka, Prof Alister Ward

Financial Markets - Foundation for Children

  • 2012: $34,980
  • 2011: $71,230
  • 2010: $36,250

Identifying underlying causes of craniofacial defects in newborns

Prof Alister Ward, Dr Daniel Mcculloch, A/Prof Nicky Kilpatrick, Dr Mike Forrester

Financial Markets - Foundation for Children

  • 2016: $24,409
  • 2015: $59,364
  • 2014: $32,514

Other Public Sector Funding

Researcher of the year (teaching & learning) award

Prof Alister Ward, Prof Evelyne de Leeuw, Prof Brendan Crotty, Dr Karen D'Souza, Ms Sharyn Milnes

  • 2009: $4,545

Equipment Grant 2009

Prof Alister Ward

  • 2009: $48,114

NHMRC Equipment Grant 2011 - MMR SRC

Prof Julian Mercer, Prof Alister Ward

  • 2011: $9,897

Delivery of MIRNA Using Genetically Modified Influenza Virus

A/Prof John Stambas, Prof Alister Ward, Prof Ken Walder, Ms Yingju Xia

  • 2014: $60,000

Characterising the role of interferons in low and highly pathogenic influenza virus infection in the chicken

Prof Alister Ward, Mr Andreas Rohringer

  • 2016: $7,000
  • 2015: $7,000
  • 2014: $7,000
  • 2013: $7,000

Anaerobic Bacterial Culture Cabinet

Prof Alister Ward

  • 2013: $22,500

NHMRC Equipment Grant 2016

Prof Alister Ward

  • 2016: $19,922

Industry and Other Funding

Establishment of the First Medical School in Geelong

Prof Wei Duan, Prof Alister Ward, Prof Brendan Crotty

  • 2007: $30,000

Impact of subterranean water on the physiology and health of Murray cod (Maccullochella peeli peeli)

Dr Paul Jones, Hon Prof Sena Desilva, Prof Giovanni Turchini, Prof Tes Toop, Prof Alister Ward

  • 2009: $5,000
  • 2008: $2,000
  • 2007: $14,000
  • 2006: $7,000

Establishment of GTRAC

Prof Alister Ward

  • 2010: $24,560
  • 2009: $22,920

CONTACT: Consortium for the evaluation of targeted cancer therapies

Prof Alister Ward, A/Prof Richard Bell

  • 2010: $88,554
  • 2009: $192,049

Deakin Cancer Research

Prof Alister Ward

  • 2012: $5,000

Automated gene expression quantification machine: qRT-PCR

Dr Yann Gibert, Prof Alister Ward

  • 2014: $33,800

Improving Cancer Diagnostics By Using Chemical Flags - Cancer Research Scholarship

Prof Alister Ward, Dr Sarah Shigdar

  • 2016: $14,000
  • 2015: $14,000

Research into the role of Proteins called cytokine receptors in ovarian cancer and the development of novel agents to suppress their effects

Prof Alister Ward, Prof Wei Duan, Dr Daniel Mcculloch

  • 2015: $12,500
  • 2014: $12,500
  • 2013: $12,500

Other Funding Sources

Collaborative High Bio-Containment immunological Research Facility

Prof Alister Ward, Dr Linfa Wang, A/Prof John Stambas, Dr John Lowenthal, Prof Ralph Tripp, Prof Bill Buttemer, Prof Johnson Mak, Prof Tania De Koning-Ward

  • 2012: $105,000
  • 2011: $100,000

ARC College - 2014 Nomination - Prof Alister Ward

Prof Alister Ward

  • 2016: $13,904

Supervisions

Principal Supervisor
2016

Andreas Rohringer

Thesis entitled: A study of the chicken IFN lambda system

Doctor of Philosophy (Medicine), School of Medicine

Robert Matthew Sertori

Thesis entitled: Investigating interleukin-2 receptor family signaling in zebrafish

Doctor of Philosophy (Medicine), School of Medicine

2015

Monique Trengove

Thesis entitled: Suppressor of cytokine signalling 4 and 5 in zebrafish development

Doctor of Philosophy (Medicine), School of Medicine

Carolyn Dancevic

Thesis entitled: Dissecting ADAMTS Proteoglycanase Biology in Development and Disease

Doctor of Philosophy (Medicine), School of Medicine

Brian Clarke

Thesis entitled: Expression of anti-viral shRNA molecules in transgenic zebrafish

Doctor of Philosophy (Medicine), School of Medicine

Parisa Rasighaemi

Thesis entitled: Dissecting the role of the ETV6 transcriptional regulator in development and disease

Doctor of Philosophy (Medicine), School of Medicine

2014

Janani Kumar

Thesis entitled: Aberrant Cytokine Signaling in Ovarian Cancer

Doctor of Philosophy (Medicine), School of Medicine

2013

Kate Goossens

Thesis entitled: Comparative analysis of type III interferon receptor and interferon-stimulated genes

Doctor of Philosophy (Medicine), School of Medicine

Michael James Dodson

Thesis entitled: The Multiple Mini-Interview (MMI) in medical student selection

Doctor of Philosophy (Medicine), School of Medicine

2011

Suzita Mohd Noor

Thesis entitled: Role of JAK2-Stats-C15 Pathway Components in Zebrafish Development

Doctor of Philosophy (Medicine), School of Medicine

2010

Liza John

Thesis entitled: The Ikaros Gene Family: Characterisation of the `Atypical' Pegasus

Doctor of Philosophy (Medicine), School of Medicine

2009

Sarah Louise Shigdar

Thesis entitled: Haematology of Murray Cod: Molecular and Cellular Analysis

Doctor of Philosophy (Medicine), School of Medicine

Clifford Liongue

Thesis entitled: Evolution of Class 1 Cytokine Receptor Signalling: Conservation of GCSFR

Doctor of Philosophy (Medicine), School of Medicine

2007

Rowena Lewis

Thesis entitled: Analysis of the stat5 Genes in Zebrafish

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2005

Sara Onnebo

Thesis entitled: Study of Myeloid Leukaemogenesis in Zebrafish

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Associate Supervisor
2017

Christopher Kintakas

Thesis entitled: ADAMTS5 expression and function in myoblast fusion and muscle regeneration

Doctor of Philosophy (Medicine), School of Medicine

2016

Scott Chisholm

Thesis entitled: Characterisation of PTEX88, a component of the Plasmodium translocon

Doctor of Philosophy (Medicine), School of Medicine

Jasmina Luczo

Thesis entitled: Pathogenesis of avian influenza: role of the haemagglutinin cleavage site motif

Doctor of Philosophy (Medicine), School of Medicine

2015

Daniel Fraher

Thesis entitled: Chemical Modulators of Lipid Abundance and Bone Development

Doctor of Philosophy (Medicine), School of Medicine

Vengama Naidu Modepalli

Thesis entitled: The Marsupial: A unique model for understanding the regulation of lung development

Doctor of Philosophy (Medicine), School of Medicine

Mohammed Jasim Mohammed Shallal

Thesis entitled: Recombinant Influenza virus as HIV vaccine vector

Doctor of Philosophy (Medicine), School of Medicine

Ashalyn Watt

Thesis entitled: Innate immunity in the breast and the role of the milk peptidome

Doctor of Philosophy (Medicine), School of Medicine

2013

Craig Wright

Thesis entitled: ROLE AND REGULATION OF G-CSF AND ITS RECEPTOR IN MUSCLE

Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences

Jia Lin

Thesis entitled: A nanoliposome-based drug delivery system for cancer

Doctor of Philosophy (Medicine), School of Medicine

2012

Katherine Birrer

Thesis entitled: Silencing Host Genes Using RNAi to Impact Virus Growth in vitro Methods for reducing cotton wax.

MAppSc (Medicine) (High cost), School of Medicine

2011

Keith Niven

Thesis entitled: Mitochondrial Division in Dictyostelium Discoideum

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2009

Lynda O'Sullivan

Thesis entitled: Dissecting the Role of socs Proteins using Zebrafish

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences