Profile image of Alister Ward

Prof Alister Ward

STAFF PROFILE

Position

Associate Head Of School (Research)

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Qualifications

Bachelor of Science, University of Melbourne, 1989
Doctor of Philosophy, University of Melbourne, 1994
Bachelor of Arts, University of Melbourne, 2001

Contact

alister.ward@deakin.edu.au
+61 3 522 72041

Research interests

The immune system is vital for maintaining good health. However, much remains to be learnt about how it develops normally, how it is perturbed in disease and how it is subverted during infection. One key facet of the immune system are the various cytokines and their receptors that regulate it. Prof. Ward leads a research team at Deakin University’s new Medical School investigating the genes involved in the development of the immune system, including cytokine receptor signalling components, with the aim of understanding their function, evolution, and role in disease. This research utilises multi-disciplinary approach, combining bioinformatics, molecular biology and functional genomics approaches in the zebrafish model.
Prof. Ward’s group is housed in the $15M Molecular Medicine Research Facility, which opened in April 2011 and contains a comprehensive suite of equipment to service molecular biology, cell biology, microscopy and histology at PC2 level. CI-Ward also oversees the ARC LIEF-funded FishWorks facility, which consists of an extensive Aquatic Habitats aquarium with a 700-tank capacity, including breeding tanks, independent light cycles, and nursery, as well as an exquisite range of equipment for zebrafish embryo manipulation and analysis, including dedicated microinjectors, fluorescence microscopes and digital cameras, and currrenlty being further upgraded.

Teaching interests

Prof. Ward has significant teaching expertise, previously serving as Year 1 & 2 Co-ordinator for Medicine and Course Director for Biomedical Science. He currently teaches into ‘Human Biology’ and ‘Infection, Defence & Repair’ in the Medical Course and ‘Immunology & Hematology’ in Biomedical Sciences, and contributes to the supervision of 3rd year, Intern, Honours and PhD students.

Knowledge areas

Prof. Ward was awarded a Bachelor of Science (Honours), Bachelor of Arts and Doctor of Philosophy from the University of Melbourne, and has then trained as a European Molecular Biology Organisation Long-Term Fellow and a Sylvia and Charles Viertel Senior Medical Research Fellow. This has provided him with significant expertise in biochemistry, genetics, functional genomics, bioinformatics, immunology, haematology and developmental biology.

Professional activities

CI-Ward has a strong presence in the local, national and international research community, illustrated by the following specific activities:

> Conference Organisation:
• 8th Australian & New Zealand Zebrafish Workshop, Geelong, Australia (2007)
- Organising Committee (Chair)
• Infection & Immunity Conference, Gold Coast, Australia (2009)
- Scientific Advisory Committee
• Emerging Infectious Diseases Conference, Geelong, Australia (2012)
- Scientific Advisory Committee
• 4th International One Health Conference, Melbourne, Australia (2016)
- Organising Committee

> Grant Review:
• Australian Research Council
- International Reader (2004-)
- College of Experts Member (2013-)
• National Health & Medical Research Council
- Project Grant Reviewer (2001-)
- Grant Review Panel Member (2011)

> Editorial Roles:
• Frontiers in Bioscience, Special Issue: ‘Granulocyte colony-stimulating factor and its receptor: roles in health and disease’
- Managing Editor (2007)
• JAK-STAT
- Editorial Board Member (2012-)
• American Journal of Experimental and Clinical Immunology
- Editorial Board Member (2012-)
• Journal of Blood Diseases
- Editorial Board Member (2014-)

> Other Peer Review, etc:
• Regular manuscripts from >15 journals, including Blood, Haematologica, and J Immunol
• Judging panels, including ASMR Vic. Premier’s Award (2006-11,14), SMART Geelong Awards (2010,12-13)
• Regular theses (1-2/year)

> Research Training:
• BSc(Hons):
- 10 completed (9 with H1 – 3 top of cohort, 9 continued to PhD)
• PhD:
- 9 completed (4 prize-winners, all continued to postdoc/faculty roles, incl. at WEHI, Peter MacCallum Cancer Institute, University College London)
- 9 current

> Leadership/Representative Roles:
• Australian Society for Biochemistry & Molecular Biology
- Review Panellist (2004)
• Australian Society for Medical Research
- Medical Research Week Committee (2000-5)
- Careers Sub-Committee (2000-4)
- Assistant to the Premier’s Award (2002-5)
- Premier’s Award Sub-Committee (2004-5), Chair (2004-5)
• BioGeelong
- Steering Committee Chair (2008-10)
• Geelong Centre for Emerging Infectious Diseases
- Steering Committee (2009-)
• Biosciences Victoria
- Deakin University rep (2010-2)
• Victorian Technology Network
- Deakin University rep (2010-)
• Research Australia
- Deakin University rep (2011)

Awards

Consistently successful at obtaining competitive funding, Professor Ward has been awarded funds totalling in excess of $4.2 million, with the majority from National Competitive Grant Schemes. He has also received a number of prestigious fellowships, including a European Molecular Biology Organisation Long-Term Fellowship, an AMRAD Postdoctoral Award and a Sylvia and Charles Viertel Senior Medical Research Fellowship. In the last 10 years these include:
• Australian Research Council Discovery Project Grant, ‘Socs proteins in health and disease’, 2005-2007 $215 000 (CI: AC Ward)
• Australian & Pacific Science Foundation Grant, ‘Impact of subterranean water on the physiology and health of Murray Cod (Maccullochella peeli peeli)’, 2006-2008 $28 000 (CIs: P Jones, S De Silva, G Turchini, T Toop, AC Ward)
• Geelong Community Foundation Grant, ‘Establishment of medical school’, 2007 $30 000 (CIs: W Duan, B Crotty, AC Ward)
• National Health & Medical Research Council Enabling Grant, ‘Australian zebrafish phenomics facility’, 2007-2011 $1 500 000 (CIs: A Perkins, B Key, J Rothnagel, A Ward, S Grimmond, P Alewood, D Hume, A Boyd, M Lardelli)
• Geelong Community Foundation, ‘Establishment of GTRAC’, 2009 $47 000 (CI: AC Ward)
• The Foundation for Children, ‘Defining mechanisms underlying skeletal muscle development and muscular dystrophy’, 2010-2012 $157 000 (CIs: D McCulloch, N Stupka, AC Ward)
• Collier Charitable Fund, ‘Study of embryonic development: automatic gene detection device’, 2012 $48 000 (CIs: Y Gibert, AC Ward)
• Australian Research Council Linkage Infrastructure Equipment Fund Grant, ‘Collaborative high bio-containment immunological research facility’, 2012 $520 000 (CIs: AC Ward, J Mak, LF Wang, J Stambas, J Lowenthal, R Tripp, TF de Koning-Ward, WA Buttemer)
• Atkins Charitable Trust, ‘Role of cytokine receptors in ovarian cancer’, 2012-2015 $42 500 (CIs: AC Ward, W Duan, D McCulloch)

Publications

Filter by

2016

Conserved IL-2Rγc signaling mediates lymphopoiesis in Zebrafish

Mr Robert Sertori, Mr Clifford Liongue, Miss Faiza Basheer, Kanako Lewis, Mrs Parisa Rasighaemi, Mr Dennis De Coninck, David Traver, Prof Alister Ward

(2016), Vol. 196, pp. 135-143, Journal of immunology, Bethesada, Md., C1

journal

Signaling via the CytoR/JAK/STAT/SOCS pathway: emergence during evolution

Mr Clifford Liongue, Ms Tarannum Taznin, Prof Alister Ward

(2016), Vol. 71, pp. 166-175, Molecular immunology, Amsterdam, The Netherlands, C1

journal
2015

Characterisation of chicken viperin

Ms Kate Elizabeth Goossens, Dr Adam Karpala, Andreas Rohringer, Prof Alister Ward, Andrew G.D Bean

(2015), Vol. 63, pp. 373-380, Molecular immunology, Amsterdam, The Netherlands, C1

journal

ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish

Mrs Parisa Rasighaemi, Sara Maria Nancy Onnebo, Mr Clifford Liongue, Prof Alister Ward

(2015), Vol. 100, pp. 23-31, Haematologica, Pavia, Italy, C1

journal

G-CSF treatment can attenuate dexamethasone-induced reduction in C2C12 myotube protein synthesis

Dr Craig Wright, Miss Erin Brown, Prof Alister Ward, Prof Aaron Russell

(2015), Vol. 73, pp. 1-7, Cytokine, Amsterdam, The Netherlands, C1

journal

Zebrafish as a model for leukemia and other hematopoietic disorders

Mrs Parisa Rasighaemi, Miss Faiza Basheer, Mr Clifford Liongue, Prof Alister Ward

(2015), Vol. 8, pp. 1-10, Journal of hematology & oncology, London, Eng., C1

journal

Functional analysis of truncated forms of ETV6

Mrs Parisa Rasighaemi, Mr Clifford Liongue, Sara Maria Nancy Onnebo, Prof Alister Ward

(2015), Vol. 171, pp. 658-662, British journal of haematology, Chichester, Eng., C1

journal

Cytokine networks and cancer stem cells

Mr Clifford Liongue, Prof Alister Ward, Prof Wei Duan, Dr Sarah Shigdar

(2015), pp. 67-87, Cancer stem cells : emerging concepts and future perspectives in translational oncology, Berlin, Germany, B1

chapter

Lipid abundance in zebrafish embryos is regulated by complementary actions of the endocannabinoid system and retinoic acid pathway

Mr Daniel Fraher, Ms Megan Ellis, Ms Shona Morrison, A/Prof Sean Mcgee, Prof Alister Ward, Prof Ken Walder, Dr Yann Gibert

(2015), Vol. 156, pp. 3596-3609, Endocrinology, Bethesda, Md., C1

journal

EpCAM aptamer-mediated survivin silencing sensitized cancer stem cells to doxorubicin in a breast cancer model

Mr Tao Wang, Michael P. Gantier, Mr Dongxi Xiang, Andrew G.D Bean, Matthew P Bruce, Shu-Feng Zhou, Dr Mustafa Khasraw, Prof Alister Ward, Li Wang, ming wei, Mr Hadi Al Shamaileh, Mr Lijue Chen, Ms Xiaodong She, Ms Jia Lin, Prof Lingxue Kong, Dr Sarah Shigdar, Prof Wei Duan

(2015), Vol. 5, pp. 1456-1472, Theranostics, Wyoming, N.S.W., C1

journal

Is low vitamin D status a risk factor for food allergy? Current evidence and future directions

Mr John Desmond Molloy, Anne-Louise Ponsonby, Dr Katrina Allen, A/Prof Mimi Tang, Dr Fiona Collier, Prof Alister Ward, Jennifer J Koplin, A/Prof Peter Vuillermin

(2015), Vol. 15, pp. 944-952, Mini-reviews in medicinal chemistry, Hilversum, The Netherlands, C1

journal

The evolutionary conservation of the A Disintegrin-like and Metalloproteinase domain with Thrombospondin-1 motif metzincins across vertebrate species and their expression in teleost zebrafish

Frederic Brunet, Ms Fiona Fraser, Ms Marley Binder, Adam Smith, Mr Chris Kintakas, Carolyn Dancevic, Prof Alister Ward, Dr Daniel Mcculloch

(2015), Vol. 15, pp. 1-15, BMC evolutionary biology, London, Eng., C1

journal
2014

Role of the interleukin 6 receptor family in epithelial ovarian cancer and its clinical implications.

Miss Janani Kumar, Prof Alister Ward

(2014), Vol. 1845, pp. 117-125, Biochimica et biophysica acta, Amsterdam, The Netherlands, C1

journal

Granulocyte colony-stimulating factor receptor mutations in myeloid malignancy

Mr Clifford Liongue, Prof Alister Ward

(2014), Vol. 4, pp. 1-7, Frontiers in oncology, Lausanne, Switzerland, C1

journal

Characterisation of chicken ZAP

Ms Kate Elizabeth Goossens, Dr Adam Karpala, Prof Alister Ward, Andrew G.D Bean

(2014), Vol. 46, pp. 373-381, Developmental & comparative immunology, Amsterdam, The Netherlands, C1

journal

Granulocyte colony-stimulating factor receptor signalling via Janus kinase 2/signal transducer and activator of transcription 3 in ovarian cancer

Miss Janani Kumar, Ms Fiona Fraser, Clyde Riley, Dr Nuzhat Ahmed, Dr Daniel Mcculloch, Prof Alister Ward

(2014), Vol. 110, pp. 133-145, British Journal of Cancer, London, England, C1

journal

ETV6 (TEL1) in blood cell development and malignancy

Mrs Parisa Rasighaemi, Mr Clifford Liongue, Prof Alister Ward

(2014), Vol. 1, pp. 1-7, Journal of blood disorders, Monroe Township, NJ, C1

journal

Cytokine Receptor Signaling in Teleosts

Mr Robert Sertori, Prof Alister Ward, Mr Clifford Liongue

(2014), pp. 39-72, Teleosts: Evolutionary Development, Diversity and Behavioral Ecology, New York, N.Y., B1

chapter
2013

Metabolic profile analysis of zebrafish embryos

Dr Yann Gibert, A/Prof Sean Mcgee, Prof Alister Ward

(2013), Vol. 71, pp. 1-5, Journal of visualized experiments, Cambridge, Mass., C1

journal

Zebrafish as a genetic model in pre-clinical drug testing and screening

Dr Yann Gibert, Dr Monique Trengove, Prof Alister Ward

(2013), Vol. 20, pp. 2458-2466, Current Medicinal Chemistry, Hilversum, Netherlands, C1

journal

Chicken interferons, their receptors and interferon-stimulated genes

Ms Kate Elizabeth Goossens, Prof Alister Ward, Dr John Lowenthal, Dr Andrew Bean

(2013), Vol. 41, pp. 370-376, Developmental and Comparative Immunology, United Kingdom, C1

journal

Evolution of the JAK-STAT pathway

Mr Clifford Liongue, Prof Alister Ward

(2013), Vol. 2, pp. e22756-1-e22756-8, JAK-STAT, Austin, Tex., C1

journal

Characterization of zebrafish polymerase iii promoters for the expression of short hairpin RNA interference molecules

Mr Brian Clarke, David M Cummins, Dr Kenneth McColl, Prof Alister Ward, Dr Timothy Doran

(2013), Vol. 10, pp. 472-479, Zebrafish, New Rochelle, NY, C1

journal

The potential link between gut microbiota and IgE-mediated food allergy in early life

Mr John Desmond Molloy, Dr Katrina Allen, Dr Fiona Collier, A/Prof Mimi Tang, Prof Alister Ward, A/Prof Peter Vuillermin

(2013), Vol. 10, pp. 7235-7256, International journal of environmental research and public health, Basel, Switzerland, C1

journal

SOCS proteins in development and disease

Dr Monique Trengove, Prof Alister Ward

(2013), Vol. 2, pp. 1-29, American journal of clinical and experimental immunology, Madison, Wi., C1

journal
2012

Evolution of JAK-STAT pathway components : mechanisms and role in immune system development

Mr Clifford Liongue, Dr Lynda O'Sullivan, Dr Monique Trengove, Prof Alister Ward

(2012), Vol. 7, pp. 1-16, PLoS one, San Francisco, Calif., C1

journal

Systematic investigation of oxygen and growth factors in clinically valid ex vivo expansion of cord blood CD34+ hematopoietic progenitor cells

Melinda L Tursky, Dr Fiona Collier, Prof Alister Ward, A/Prof Mark Kirkland

(2012), Vol. 14, pp. 679-685, Cytotherapy, Oxford, England, C1

journal

Koi herpesvirus encodes and expresses a functional interleukin-10

Agus Sunarto, Mr Clifford Liongue, Dr Kenneth McColl, Matthew M. Adams, Dieter Bulach, Mark Crane, Karel A. Schat, Barry Slobedman, Andrew C. Barnes, Prof Alister Ward, Peter J. Walker

(2012), Vol. 86, pp. 11512-11520, Journal of virology, Washington, D.C., C1

journal
2011

Clinical applications of aptamers and nucleic acid therapeutics in haematological malignancies

Dr Sarah Shigdar, Prof Alister Ward, Abhijit De, Chaoyong J. Yang, Ming Qian Wei, Prof Wei Duan

(2011), Vol. 155, pp. 3-13, British journal of haematology, Oxford, U. K., C1

journal

Shooting the messenger : targeting signal transduction pathways in leukemia and related disorders

Suzita Mohd Noor, A/Prof Richard Bell, Prof Alister Ward

(2011), Vol. 78, pp. 33-44, Critical reviews in oncology / hematology, Clare, Ireland, C1

journal

Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile

Ardian Latifi, Khalid Abubaker, Natalie Castrechini, Prof Alister Ward, Mr Clifford Liongue, Francoise Dobill, Miss Janani Kumar, A/Prof Erik Thompson, Michael A. Quinn, Jock Findlay, Dr Nuzhat Ahmed

(2011), Vol. 112, pp. 2850-2864, Journal of cellular biochemistry, Hoboken N.J., C1

journal

The Ikaros gene family : transcriptional regulators of hematopoiesis and immunity

Dr Liza John, Prof Alister Ward

(2011), Vol. 48, pp. 1272-1278, Molecular immunology, Oxford, U. K., C1

journal

Origins of adaptive immunity

Mr Clifford Liongue, Dr Liza John, Prof Alister Ward

(2011), Vol. 31, pp. 61-71, Critical reviews in immunology, Redding, Conn., C1

journal
2009

Altering presenilin gene activity in zebrafish embryos causes changes in expression of genes with potential involvement in alzheimer's disease pathogenesis

Morgan Newman, Ben Tucker, Svanhild Nornes, Prof Alister Ward, Dr Michael Lardelli

(2009), Vol. 16, pp. 133-147, Journal of alzheimer's disease, Amsterdam, The Netherlands, C1-1

journal

Zebrafish granulocyte colony-stimulatingZebrafish granulocyte colony-stimulating factor receptor signaling promotes myelopoiesis and myeloid cell migration

Mr Clifford Liongue, Chris J. Hall, Miss Bree Aimee O'Connell, Phil Crosier, Prof Alister Ward

(2009), Vol. 113, pp. 2535-2546, Blood, Washington, D.C., C1

journal

Evolution of the ikaros gene family : implications for the origins of adaptive immunity

Dr Liza John, Mr Simon Yoong, Prof Alister Ward

(2009), Vol. 182, pp. 4792-4799, The journal of immunology, Bethesda, Md., C1

journal

Cytochemical characterisation of the leucocytes and thrombocytes from murray cod (Maccullochella peelii peelii, Mitchell)

Dr Sarah Shigdar, Andrew Harford, Prof Alister Ward

(2009), Vol. 26, pp. 731-736, Fish and shellfish immunology, Amsterdam, The Netherlands, C1

journal

Suppressors of cytokine signaling : functions in normal biology and roles in disease

Prof Alister Ward, Anna Barry, Dr Lynda O'Sullivan

(2009), pp. 10-23, Jak-stat pathway in disease, Austin, Tex., B1

chapter

Granulocyte colony-stimulating factor receptor: stimulating granulopoiesis and much more

Mr Clifford Liongue, Dr Craig Wright, Prof Aaron Russell, Prof Alister Ward

(2009), Vol. 41, pp. 2372-2375, International journal of biochemistry and cell biology, Amsterdam, The Netherlands, C1

journal

A novel zebrafish jak2a V581F model shared features of human JAK2 V617F polycythemia vera

Alvin C. H. Ma, August Fan, Prof Alister Ward, Mr Clifford Liongue, Dr Rowena Lord, Suk H. Cheng, P. K. Chan, Sze-Fai Yip, Raymond Liang, Anskar Y. H. Leung

(2009), Vol. 37, pp. 1379-1386, Experimental hematology, Amsterdam, The Netherlands, C1

journal

Genetic and molecular diagnosis of severe congenital neutropenia

Prof Alister Ward, David C Dale

(2009), Vol. 16, pp. 9-13, Current opinion in hematology, Philadelphia, Pa., C1

journal
2008

Stat5 as a diagnostic marker for leukemia

Dr Rowena Lord, Prof Alister Ward

(2008), Vol. 8, pp. 73-82, Expert review of molecular diagnostics, London, England, C1

journal

Functional interaction between mutations in the granulocyte colony-stimulating factor receptor in severe congenital neutropenia

Prof Alister Ward, Judith Gits, Fidel Majeed, Andrew A Aprikyan, Dr Rowena Lord, Dr Lynda O'Sullivan, Melvin Freedman, Dr Sarah Shigdar, Ivo P Touw, David C Dale, Yigal Dror

(2008), Vol. 142, pp. 653-656, British journal of haematology, Oxford, England, C1

journal
2007

STAT3 signaling is activated in human skeletal muscle following acute resistance exercise

Dr Marissa Caldow, Dr Kate Carey (nee Mehan), Prof Alister Ward, A/Prof David Cameron-Smith

(2007), Vol. 102, pp. 1483-1489, Journal of applied physiology, Bethesda, Md., C1

journal

Characterization of the zebrafish matrix metalloproteinase 9 gene and its developmental expression pattern

Mr Simon Yoong, Miss Bree Aimee O'Connell, Anna Soanes, Meredith O. Crowhurst, Graham J. Lieschke, Prof Alister Ward

(2007), Vol. 7, pp. 39-46, Gene expression patterns, Amsterdam, The Netherlands, C1

journal

Blood cells of Murray cod maccullochella peelii peelii (Mitchell)

Dr Sarah Shigdar, Mr Dan Cook, Dr Paul Jones, Andrew Harford, Prof Alister Ward

(2007), Vol. 70, pp. 973-980, Journal of fish biology, Oxford, England, C1

journal

Heterologous microarray experiments used to identify the early gene response to heat stress in a coral reef fish

Karin S. Kassahn, M. Julian Caley, Prof Alister Ward, Ashley Connolly, Glenn Stone, Ross H. Crozier

(2007), Vol. 16, pp. 1749-1763, Molecular ecology, Oxford, England, C1

journal

The role of jak2a in zebrafish hematopoiesis

Alvin C. H. Ma, Prof Alister Ward, Raymond Liang, Anskar Y. H. Leung

(2007), Vol. 110, pp. 1824-1830, Blood, Washington, D.C., C1

journal

Evolution of class I cytokine receptors

Mr Clifford Liongue, Prof Alister Ward

(2007), Vol. 7, pp. 1-15, BMC evolutionary biology, London, England, C1

journal

The myeloproliferative disorder-associated JAK2 V617F mutant escapes negative regulation by suppressor of cytokine signaling 3

Michelle B. Hookham, Joanne Elliott, Yvonne Suessmuth, Judith Staerk, Prof Alister Ward, William Vainchenker, Melanie J. Percy, Mary Frances McMullin, Stefan N. Constantinescu, James A. Johnston

(2007), Vol. 109, pp. 4924-4929, Blood, Washington, D.C., Wash., C1

journal

From transcriptome to biological function: environmental stress in an ectothermic vertebrate, the coral reef fish Pomacentrus moluccensis

Karin S. Kassahn, Ross H. Crozier, Prof Alister Ward, Glenn Stone, M. Julian Caley

(2007), Vol. 8, pp. 1-16, BMC Genomics, London, England, C1

journal

The role of the granulocyte colony-stimulating factor receptor (G-CSF-R) in disease

Prof Alister Ward

(2007), Vol. 12, pp. 608-618, Frontiers in bioscience, Tampa, Florida, C1

journal
2006

Multiple pathways contribute to the hyperproliferative responses from truncated granulocyte colony-stimulating factor receptors

Judith Gits, Daphne van Leeuwen, H.P. Carroll, Ivo P Touw, Prof Alister Ward

(2006), Vol. 20, pp. 2111-2118, Leukemia, Houndmills, England, C1

journal

Constitutive activation of zebrafish Stat5 expands hematopoietic cell populations in vivo

Dr Rowena Lord, Sarah E.M. Stephenson, Prof Alister Ward

(2006), Vol. 34, pp. 179-187, Experimental hematology, New York, N.Y., C1

journal
2005

Hematopoietic perturbation in zebrafish expressing a tel-jak2a fusion

Sara Maria Nancy Onnebo, Melaine M. Condron, Dora O. McPhee, Graham J. Lieschke, Prof Alister Ward

(2005), Vol. 33, pp. 182-188, Experimental hematology, Amsterdam , The Netherlands, C1

journal

RBMX gene is essential for brain development in Zebrafish

Enkhjargal Tsend-Ayush, Lynda A. O`Sullivan, Frank. S. Grutzner, Sara Maria Nancy Onnebo, Dr Rowena Lord, Margaret L. Delbridge, Jennifer. A. Marshall Graves, Prof Alister Ward

(2005), Vol. 234, pp. 682-688, Developmental dynamics, Hoboken, N.J., C1

journal
2004

Receptor activation and 2 distinct COOH- terminal motifs control G-CSF receptor distribution and internalization kinetics.

Lambertus H.J. Aarts, Onno Roovers, Prof Alister Ward, Ivo P Touw

(2004), Vol. 103, pp. 571-579, Blood, Washington, D.C., C1-1

journal

Conservation, duplication and divergence of the zebrafish stat5 genes

Dr Rowena Lord, Prof Alister Ward

(2004), Vol. 338, pp. 65-74, Gene, Amsterdam, The Netherlands, C1

journal

Harnessing zebrafish for the study of white blood cell development and its perturbation

Sara Maria Nancy Onnebo, Mr Simon Yoong, Prof Alister Ward

(2004), Vol. 32, pp. 789-796, Experimental hematology, Amsterdam, The Netherlands, C1

journal
2003

Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells

Mirjam H. A. Hermans, Gert-Jan van de Geijn, Claudia Antonissen, Judith Gits, Daphne van Leeuwen, Prof Alister Ward, Ivo P Touw

(2003), Vol. 101, pp. 2584-2590, Blood, Washington, D.C., C1

journal

The zebrafish spil promoter drives myeloid-specific expression in stable transgenic fish

Prof Alister Ward, Dora O. McPhee, Melaine M. Condron, Sony Varma, Stephen H. Cody, Sara Maria Nancy Onnebo, Barry H. Paw, Leonard I Zon, Graham J. Lieschke

(2003), Vol. 102, pp. 3238-3240, Blood, Washington, D.C., Wash., C1

journal
2002

Tyrosine residues of the granulocyte colony-stimulating factor transmit proliferation and differentiation signals in murine bone marrow cells

Shiva Arkbarzadeh, Prof Alister Ward, Dora O. McPhee, Warren S. Alexander, Graham J. Lieschke, Judith E. Layton

(2002), Vol. 99, pp. 879-887, Blood, Washington D.C., C1-1

journal

Specificity and affinity motifs for Grb2 SH2-ligand interactions

Helmut W. H. G. Kessels, Prof Alister Ward, Ton N. M. Schumacher

(2002), Vol. 99, pp. 8524-8529, Proceedings of the National Academy of Sciences, Washington, D.C., C1-1

journal

Zebrafish SPI-1 marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning.

Graham J. Lieschke, Andrew C. Oates, Barry H. Paw, Margaret A. Thompson, Nathan E. Hall, Prof Alister Ward, Robert K. Ho, Leonard I Zon, Judith E. Layton

(2002), Vol. 246, pp. 274-295, Developmental biology, Amsterdam, The Netherlands, C1-1

journal

The zebrafish as a model system for human disease

Prof Alister Ward, Graham J. Lieschke

(2002), Vol. 7, pp. d827-d833, Frontiers in bioscience, Tampa, Fla., C1-1

journal

G-CSF: function and modes of action (Review)

Sunanda Basu, Ashley Dunn, Prof Alister Ward

(2002), Vol. 10, pp. 3-10, International journal of molecular medicine, Athens, Greece, C1-1

journal

Stats and hematopoiesis

Prof Alister Ward

(2002), pp. 78-91, Jak-stat pathway in hematopoiesis and disease, Georgetown, Tex., B1

chapter
2001

C/EBPÁ and G-CSF receptor signals cooperate to induce the myeloperoxidase and neutrophil elastase genes

W Wang, X Wang, Prof Alister Ward, Ivo P Touw, AD Friedman

(2001), Vol. 15, pp. 779-786, Leukemia, London, England, C1-1

journal

Proteomic analysis of macrophage differentiation

Xavier F. Csar, Nicholas J. Wilson, Kerrie-Ann McMahon, Denese C. Marks, Tina L. Beecroft, Prof Alister Ward, Genevieve A. Whitty, Varuni Kanangasundarum, John A. Hamilton

(2001), Vol. 276, pp. 26211-26217, Journal of Biological Chemistry, United States, C1-1

journal

Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish.

Graham J. Lieschke, Andrew C. Oates, Meredith O. Crowhurst, Prof Alister Ward, Judith E. Layton

(2001), Vol. 98, pp. 3087-3096, Blood, Washington, D.C., Wash., C1-1

journal

Copper/zinc superoxide dismutase is phosphorylated and modulated specifically by granulocyte-colony stimulating factor in myeloid cells.

Xavier F. Csar, Nicholas J. Wilson, Philip Strike, Lindsay Sparrow, Kerrie-Ann McMahon, Prof Alister Ward, John A. Hamilton

(2001), Vol. 1, pp. 435-443, Proteomics, Weinheim, Germany, C1-1

journal

Somatostatin modulates G-CSF-induced but not interleukin-3-induced proliferative responses in myeloid 32D cells via activation of somatostatin receptor subtype 2

Sigrid Oomen, Prof Alister Ward, Leo Hofland, Steven Lamberts, Bob L¿¿wenberg, Ivo P Touw

(2001), Vol. 2, pp. 322-329, Hematology journal: the official journal of the European haematology association / EHA, London, England, C1-1

journal