Dr Daniel Mcculloch

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Position

Visitor

Faculty

Faculty of Health

Department

School of Medicine

Campus

Off-Campus (Home)

Publications

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2016

The ADAMTS hyalectanase family: biological insights from diverse species

C Dancevic, D McCulloch, A Ward

(2016), Vol. 473, pp. 2011-2022, Biochemical journal, London, Eng., C1

journal
2015

The evolutionary conservation of the A Disintegrin-like and Metalloproteinase domain with Thrombospondin-1 motif metzincins across vertebrate species and their expression in teleost zebrafish

F Brunet, F Fraser, M Binder, A Smith, C Kintakas, C Dancevic, A Ward, D McCulloch

(2015), Vol. 15, pp. 1-15, BMC evolutionary biology, London, Eng., C1

journal
2014

Granulocyte colony-stimulating factor receptor signalling via Janus kinase 2/signal transducer and activator of transcription 3 in ovarian cancer

J Kumar, F Fraser, C Riley, N Ahmed, D McCulloch, A Ward

(2014), Vol. 110, pp. 133-145, British Journal of Cancer, London, England, C1

journal

Current and emerging therapeutic strategies for preventing inflammation and aggrecanase-mediated cartilage destruction in arthritis

C Dancevic, D McCulloch

(2014), Vol. 16, pp. 1-11, Arthritis research and therapy, London, England, C1

journal

ADAMTS4 and ADAMTS5 knockout mice are protected from versican but not aggrecan or brevican proteolysis during spinal cord injury.

Kadir Demircan, Vehap Topcu, Tomoyuki Takigawa, Sumeyya Akyol, Tomoko Yonezawa, Gulfer Ozturk, Veli Ugurcu, Rukiye Hasgul, M Yigitoglu, Omer Akyol, Daniel McCulloch, Satoshi Hirohata

(2014), Vol. 2014, pp. 693746-, Biomed Res Int, United States, C1

journal
2013

Versican processing by a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats proteinases-5 and -15 facilitates myoblast fusion

N Stupka, C Kintakas, J White, F Fraser, M Hanciu, N Aramaki-Hattori, S Martin, C Coles, F Collier, A Ward, S Apte, D McCulloch

(2013), Vol. 288, pp. 1907-1917, Journal of biological chemistry, Bethesda, Maryland, C1

journal

Biosynthesis and expression of a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats-15

C Dancevic, F Fraser, A Smith, N Stupka, A Ward, D McCulloch

(2013), Vol. 288, pp. 37267-37276, Journal of Biological Chemistry, Rockville, Md., C1

journal

Hyaluronan Synthesis and Myogenesis: A requirement for hyaluronan synthesis during myogenic differentiation independent of pericullular matrix formation

L Hunt, C Gorman, C Kintakas, D McCulloch, E Mackie, J White

(2013), Vol. 288, pp. 13006-13021, Journal of Biological Chemistry, Rockville, MD, C1

journal
2012

Adamts5 (Aggrecanase-2) is widely expressed in the mouse musculoskeletal system and is induced in specific regions of knee joint explants by inflammatory cytokines

J Wylie, J Ho, S Singh, D McCulloch, S Apte

(2012), Vol. 30, pp. 226-233, Journal of orthopaedic research, Hoboken N.J., C1

journal
2011

Altered versican cleavage in ADAMTS5 deficient mice : a novel etiology of myxomatous valve disease

L Dupuis, D McCulloch, J McGarity, A Bahan, A Wessels, D Weber, A Diminich, C Nelson, S Apte, C Kern

(2011), Vol. 357, pp. 152-164, Developmental biology, Maryland Heights, Mo., C1

journal

Emerging roles for ADAMTS5 during development and disease

C Kintakas, D McCulloch

(2011), Vol. 30, pp. 311-317, Matrix biology, Amsterdam, Netherlands, C1

journal
2010

10 mM glucosamine prevents activation of proADAMTS5 (aggrecanase-2) in transfected cells by interference with post-translational modification of furin

D McCulloch, J Wiley, J Longpre, R Leduc, S Apte

(2010), Vol. 18, pp. 455-463, Osteoarthritis and cartilage, London, England, C1

journal
2009

Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues.

D McCulloch, C Le Goff, S Bhatt, L Dixon, J Sandy, S Apte

(2009), Vol. 9, pp. 314-323, Gene expression patterns, Amsterdam, The Netherlands, C1-1

journal

Characterization of proADAMTS5 processing by proprotein convertases.

J Longpré, D McCulloch, B Koo, J Alexander, S Apte, R Leduc

(2009), Vol. 41, pp. 1116-1126, International journal of biochemistry and cell biology, Amsterdam, The Netherlands, C1-1

journal

ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression

D McCulloch, C Nelson, L Dixon, D Silver, J Wylie, V Lindner, T Sasaki, M Cooley, W Argraves, S Apte

(2009), Vol. 17, pp. 687-698, Developmental cell, Cambridge, Mass., C1-1

journal
2005

BM18: A novel androgen-dependent human prostate cancer xenograft model derived from a bone metastasis

D McCulloch, K Opeskin, E Thompson, E Williams

(2005), Vol. 65, pp. 35-43, The prostate, Hoboken, N.J., C1-1

journal

Upregulated MT1-MMP/TIMP-2 axis in the TSU-Pr1-B1/B2 model of metastatic progression in transitional cell carcinoma of the bladder

C Chaffer, B Dophide, D McCulloch, A Lee, J Moseley, E Thompson, E Williams

(2005), Vol. 22, pp. 115-125, Clinical and experimental metastasis, Dordrecht, Netherlands, C1-1

journal
2004

Expression of the disintegrin metalloprotease ADAM-10 in prostate cancer and its regulation by dihydrotestosterone, insulin like growth factor -1 and epidermal growth factor in the prostate cell model LNCaP

D McCulloch, P Akl, H Samarutunga, A Herington, D Odorico

(2004), Vol. 10, pp. 314-323, Clinical cancer research, Philadelphia, Pa., C1-1

journal
2003

Modeling of enzyme-substrate complexes for the metalloproteases MMP-3, ADAM-9 and ADAM-10

S Manzetti, D McCulloch, A Herington, D van der Spoel

(2003), Vol. 17, pp. 551-565, Journal of computer aided molecular design, Dordrecht , The Netherlands, C1-1

journal
2000

The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone

D McCulloch, M Harvey, A Herington

(2000), Vol. 167, pp. 11-21, Molecular and cellular endocringology, Shannon, Ireland, C1-1

journal

Funded Projects at Deakin

Australian Competitive Grants

Defining mechanisms underlying skeletal muscle development and muscular dystrophy

Dr Daniel Mcculloch, Dr Nicole Stupka, Prof Alister Ward

Financial Markets - Foundation for Children

  • 2012: $34,980
  • 2011: $71,230
  • 2010: $36,250

Identifying underlying causes of craniofacial defects in newborns

Prof Alister Ward, Dr Daniel Mcculloch, A/Prof Nicky Kilpatrick, Dr Mike Forrester

Financial Markets - Foundation for Children

  • 2016: $24,409
  • 2015: $59,364
  • 2014: $32,514

Industry and Other Funding

The effect of Statins on Joint Health

Dr Daniel Mcculloch

  • 2013: $15,000

Muscular Dystrophy: fishing for a cure

Dr Daniel Mcculloch

  • 2014: $9,178

Research into the role of Proteins called cytokine receptors in ovarian cancer and the development of novel agents to suppress their effects

Prof Alister Ward, Prof Wei Duan, Dr Daniel Mcculloch

  • 2015: $12,500
  • 2014: $12,500
  • 2013: $12,500

Supervisions

Associate Supervisor
2017

Meagan McMahon

Thesis entitled: The role of ADAMTS enzymes in influenza virus immunity

Doctor of Philosophy (Medicine), School of Medicine

2015

Parisa Rasighaemi

Thesis entitled: Dissecting the role of the ETV6 transcriptional regulator in development and disease

Doctor of Philosophy (Medicine), School of Medicine

2014

Janani Kumar

Thesis entitled: Aberrant Cytokine Signaling in Ovarian Cancer

Doctor of Philosophy (Medicine), School of Medicine

2011

Suzita Mohd Noor

Thesis entitled: Role of JAK2-Stats-C15 Pathway Components in Zebrafish Development

Doctor of Philosophy (Medicine), School of Medicine