Dr Daniel Mcculloch





Faculty of Health


School of Medicine


Off-Campus (Home)


Filter by


The ADAMTS hyalectanase family: biological insights from diverse species

Miss Carolyn Dancevic, Dr Daniel Mcculloch, Prof Alister Ward

(2016), Vol. 473, pp. 2011-2022, Biochemical journal, London, Eng., C1


ADAMTS5 is a critical regulator of virus-specific T cell immunity

Ms Meagan Mcmahon, Dr Siying Ye, Dr Leonard Izzard, Dr Daniel Dlugolenski, Dr Daniel Mcculloch, A/Prof John Stambas

(2016), Vol. 14, pp. 1-22, PLoS biology, San Francisco, Calif., C1


The evolutionary conservation of the A Disintegrin-like and Metalloproteinase domain with Thrombospondin-1 motif metzincins across vertebrate species and their expression in teleost zebrafish

Frederic Brunet, Ms Fiona Fraser, Dr Marley Binder, Adam Smith, Mr Chris Kintakas, Miss Carolyn Dancevic, Prof Alister Ward, Dr Daniel Mcculloch

(2015), Vol. 15, pp. 1-15, BMC evolutionary biology, London, Eng., C1


Granulocyte colony-stimulating factor receptor signalling via Janus kinase 2/signal transducer and activator of transcription 3 in ovarian cancer

Miss Janani Kumar, Ms Fiona Fraser, Clyde Riley, Dr Nuzhat Ahmed, Dr Daniel Mcculloch, Prof Alister Ward

(2014), Vol. 110, pp. 133-145, British Journal of Cancer, London, England, C1


ADAMTS4 and ADAMTS5 knockout mice are protected from versican but not aggrecan or brevican proteolysis during spinal cord injury

Kadir Demircan, Vehap Topcu, Tomoyuki Takigawa, Sumeyya Akyol, Tomoko Yonezawa, Gulfer Ozturk, Veli Ugurcu, Rukiye Hasgul, M. Ramazan Yigitoglu, Omer Akyol, Dr Daniel Mcculloch, Satoshi Hirohata

(2014), Vol. 2014, pp. 1-8, Biomed Research International, New York, NY, C1


Current and emerging therapeutic strategies for preventing inflammation and aggrecanase-mediated cartilage destruction in arthritis

Miss Carolyn Dancevic, Dr Daniel Mcculloch

(2014), Vol. 16, pp. 1-11, Arthritis research and therapy, London, England, C1


Versican processing by a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats proteinases-5 and -15 facilitates myoblast fusion

Dr Nicole Stupka, Mr Chris Kintakas, Dr Jason White, Ms Fiona Fraser, Michael Hanciu, Noriko Aramaki-Hattori, Miss Sheree Martin, Chantal Coles, Dr Fiona Collier, Prof Alister Ward, Suneel S Apte, Dr Daniel Mcculloch

(2013), Vol. 288, pp. 1907-1917, The Journal of Biological Chemistry, Bethesda, Maryland, C1


Biosynthesis and expression of a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats-15

Miss Carolyn Dancevic, Ms Fiona Fraser, Adam Smith, Dr Nicole Stupka, Prof Alister Ward, Dr Daniel Mcculloch

(2013), Vol. 288, pp. 37267-37276, Journal of Biological Chemistry, Rockville, Md., C1


Hyaluronan Synthesis and Myogenesis: A requirement for hyaluronan synthesis during myogenic differentiation independent of pericullular matrix formation

Liam C Hunt, Chris Gorman, Mr Chris Kintakas, Dr Daniel Mcculloch, Eleanor J Mackie, Dr Jason White

(2013), Vol. 288, pp. 13006-13021, Journal of Biological Chemistry, Rockville, MD, C1


Adamts5 (Aggrecanase-2) is widely expressed in the mouse musculoskeletal system and is induced in specific regions of knee joint explants by inflammatory cytokines

James D. Wylie, Jason C. Ho, Shweta Singh, Dr Daniel Mcculloch, Suneel S Apte

(2012), Vol. 30, pp. 226-233, Journal of orthopaedic research, Hoboken N.J., C1


Emerging roles for ADAMTS5 during development and disease

Mr Chris Kintakas, Dr Daniel Mcculloch

(2011), Vol. 30, pp. 311-317, Matrix biology, Amsterdam, Netherlands, C1


Altered versican cleavage in ADAMTS5 deficient mice : a novel etiology of myxomatous valve disease

Loren E. Dupuis, Dr Daniel Mcculloch, Jessica D. McGarity, Alexandria Bahan, Andy Wessels, Deidra Weber, A. Megan Diminich, Courtney M. Nelson, Suneel S Apte, Christine B. Kern

(2011), Vol. 357, pp. 152-164, Developmental biology, Maryland Heights, Mo., C1


10 mM glucosamine prevents activation of proADAMTS5 (aggrecanase-2) in transfected cells by interference with post-translational modification of furin

Dr Daniel Mcculloch, James Wiley, Jean-Michel Longpr¿¿, Richard Leduc, Suneel S Apte

(2010), Vol. 18, pp. 455-463, Osteoarthritis and cartilage, London, England, C1


ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression

Dr Daniel Mcculloch, Courtney M. Nelson, Laura J Dixon, Debra L. Silver, James D. Wylie, Volkhard Lindner, Takako Sasaki, Marion A. Cooley, W. Scott Argraves, Suneel S Apte

(2009), Vol. 17, pp. 687-698, Developmental cell, Cambridge, Mass., C1-1


Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues.

Dr Daniel Mcculloch, Carine Le Goff, Sumantha Bhatt, Laura J Dixon, John D Sandy, Suneel S Apte

(2009), Vol. 9, pp. 314-323, Gene expression patterns, Amsterdam, The Netherlands, C1-1


Characterization of proADAMTS5 processing by proprotein convertases.

Jean-Michel Longpr¿¿, Dr Daniel Mcculloch, Bon-Hun Koo, Jo Alexander, Suneel S Apte, Richard Leduc

(2009), Vol. 41, pp. 1116-1126, International journal of biochemistry and cell biology, Amsterdam, The Netherlands, C1-1


BM18: A novel androgen-dependent human prostate cancer xenograft model derived from a bone metastasis

Dr Daniel Mcculloch, Kenneth Opeskin, A/Prof Erik Thompson, Dr Elizabeth D Williams

(2005), Vol. 65, pp. 35-43, The prostate, Hoboken, N.J., C1-1


Upregulated MT1-MMP/TIMP-2 axis in the TSU-Pr1-B1/B2 model of metastatic progression in transitional cell carcinoma of the bladder

Christine Chaffer, Bonnie Dophide, Dr Daniel Mcculloch, Allan B Lee, Jane M. Moseley, A/Prof Erik Thompson, Dr Elizabeth D Williams

(2005), Vol. 22, pp. 115-125, Clinical and experimental metastasis, Dordrecht, Netherlands, C1-1


Expression of the disintegrin metalloprotease ADAM-10 in prostate cancer and its regulation by dihydrotestosterone, insulin like growth factor -1 and epidermal growth factor in the prostate cell model LNCaP

Dr Daniel Mcculloch, Pascal Akl, Hemamali Samarutunga, Adrian C. Herington, Dimitri M. Odorico

(2004), Vol. 10, pp. 314-323, Clinical cancer research, Philadelphia, Pa., C1-1


Modeling of enzyme–substrate complexes for the metalloproteases MMP-3, ADAM-9 and ADAM-10

Sergio Manzetti, Dr Daniel Mcculloch, Adrian C. Herington, David van der Spoel

(2003), Vol. 17, pp. 551-565, Journal of computer aided molecular design, Dordrecht , The Netherlands, C1-1


The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone

Dr Daniel Mcculloch, Mark Harvey, Adrian C. Herington

(2000), Vol. 167, pp. 11-21, Molecular and cellular endocringology, Shannon, Ireland, C1-1



Australian Competitive Grants

Defining mechanisms underlying skeletal muscle development and muscular dystrophy

Dr Daniel Mcculloch, Dr Nicole Stupka, Prof Alister Ward

Financial Markets - Foundation for Children

  • 2012: $34,980
  • 2011: $71,230
  • 2010: $36,250

Identifying underlying causes of craniofacial defects in newborns

Dr Daniel Mcculloch, Prof Alister Ward, A/Prof Nicky Kilpatrick, Dr Mike Forrester

Financial Markets - Foundation for Children

  • 2016: $24,409
  • 2015: $59,364
  • 2014: $32,514

Industry and Other Funding

The effect of Statins on Joint Health

Dr Daniel Mcculloch

  • 2013: $15,000

Muscular Dystrophy: fishing for a cure

Dr Daniel Mcculloch

  • 2014: $9,178

Research into the role of Proteins called cytokine receptors in ovarian cancer and the development of novel agents to suppress their effects

Prof Alister Ward, Prof Wei Duan, Dr Daniel Mcculloch

  • 2015: $12,500
  • 2014: $12,500
  • 2013: $12,500


Associate Supervisor

Meagan McMahon

Thesis entitled: The role of ADAMTS enzymes in influenza virus immunity

Doctor of Philosophy (Medicine), School of Medicine


Parisa Rasighaemi

Thesis entitled: Dissecting the role of the ETV6 transcriptional regulator in development and disease

Doctor of Philosophy (Medicine), School of Medicine


Janani Kumar

Thesis entitled: Aberrant Cytokine Signaling in Ovarian Cancer

Doctor of Philosophy (Medicine), School of Medicine


Suzita Mohd Noor

Thesis entitled: Role of JAK2-Stats-C15 Pathway Components in Zebrafish Development

Doctor of Philosophy (Medicine), School of Medicine