Dr Delphine Denoyer



Research Fellow (Grade 2)


Faculty of Sci Eng & Built Env


School of Life & Env. Sciences


Melbourne Burwood Campus


+61 3 924 45432


Dr Delphine Denoyer is a research fellow in the Centre for Cellular and Molecular Biology at Deakin University. She obtained her PhD in Biomedical Engineering in France in 2004, where she investigated the mechanisms of uptake of new radiopharmaceuticals in cancer cells. After being awarded a prestigious fellowship from NHMRC/INSERM (Australia/France research cooperation program), she relocated to Australia in 2007 to pursue her interest in preclinical validation of radiopharmaceuticals for imaging and therapy of cancers at the Peter MacCallum Cancer Centre, Melbourne. In November 2013, she joined the Metals in Medicine Laboratory. Her research focus moved to the metallomics field where she uses her expertise in translational research to investigate the role of copper in the development and growth of prostate cancer.

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Knowledge areas

Translational Research

Cancer Biology (in particular melanoma, prostate and breast cancers)


Preclinical validation of new compounds for imaging and therapy of cancer

PET/SPECT imaging, autoradiography


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Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution

Dr Delphine Denoyer, Helen Pearson, Miss Sharnel Clatworthy, Dr Zoe Smith, Prof Paul Francis, Dr Roxana Llanos, Irene Volitakis, Wayne Phillips, Mr Peter Meggyesy, Mr Shashank Masaldan, Dr Michael Cater

(2016), Vol. 7, pp. 37064-37080, Oncotarget, Albany, N.Y., C1


Ceruloplasmin is regulated by copper and lactational hormones in PMC42-LA mammary epithelial cell culture models

Dr David Freestone, Dr Delphine Denoyer, Mr MATTHEW JAKAB, Prof Leigh Ackland, Dr Michael Cater, Dr Agnes Michalczyk

(2016), Vol. 8, pp. 941-950, Metallomics, Cambridge, Eng., C1


Tumour but not stromal expression of β3 integrin is essential, and is required early, for spontaneous dissemination of bone-metastatic breast cancer.

Rachel Zoe Carter, Kelli Micocci, Anthony Natoli, Richard P Redvers, Sophie Paquet-Fifield, Ana Martin, Dr Delphine Denoyer, Xiawei Ling, Soo-Hyun Kim, Rebeka Tomasin, Heloisa Selistre-de-Araujo, Robin L. Anderson, Normand Pouliot

(2015), Vol. 235, pp. 760-772, Journal of Pathology, England, C1-1


Synthesis and in vivo evaluation of [123I]melanin-targeted agents

Maxine Roberts, Mr Vu Nguyen, Mark Ashford, Paula Berghofer, Naomi Wyatt, Anwen Krause-Heuer, Tien Q Pham, Stephen R Taylor, Leena Hogan, Cathy Jiang, Benjamin Fraser, Nigel Lengkeek, Lidia Matesic, Marie-Claude Gregoire, Dr Delphine Denoyer, Rodney J. Hicks, Dr Andrew Katsifis, Ivan Greguric

(2015), Vol. 58, pp. 6214-6224, Journal of medicinal chemistry, Washington, DC., C1-1


Targeting copper in cancer therapy: ‘copper that cancer’

Dr Delphine Denoyer, Mr Shashank Masaldan, Dr Sharon La Fontaine, Dr Michael Cater

(2015), Vol. 7, pp. 1459-1476, Metallomics, London, Eng., C1


Heterogeneous copper concentrations in cancerous human prostate tissues

Dr Delphine Denoyer, Miss Sharnel Clatworthy, Mr Shashank Masaldan, Mr Peter Meggyesy, Dr Michael Cater

(2015), Vol. 75, pp. 1510-1517, Prostate, London, Eng., C1


Analysis of 177Lu-octreotate therapy-induced DNA damage in peripheral blood lymphocytes of patients with neuroendocrine tumors

Dr Delphine Denoyer, Pavel Lobachevsky, Price Jackson, Mick Thompson, Olga A Martin, Rodney J. Hicks

(2015), Vol. 56, pp. 505-511, Journal of Nuclear Medicine, New York, N.Y., C1


Bone-derived soluble factors and laminin-511 cooperate to promote migration, invasion and survival of bone-metastatic breast tumor cells

Dr Delphine Denoyer, Nicole Kusuma, Allan Burrows, Xiawei Ling, Lara Jupp, Robin L. Anderson, Normand Pouliot

(2014), Vol. 32, pp. 63-73, Growth factors, London, England, C1-1


Foxp3 expression in macrophages associated with RENCA tumors in mice.

Christel Devaud, Carmen Yong, Dr Liza John, Jennifer Westwood, Connie Duong, Colin House, Dr Delphine Denoyer, Jason Li, Dr Phillip Darcy, Michael Kershaw

(2014), Vol. 9, pp. 1-8, PLoS One, San Francisco, Calif., C1-1


Enhanced lithium-induced brain recovery following cranial irradiation is not impeded by inflammation

Jordane Malaterre, Cameron S McPherson, Dr Delphine Denoyer, Emily Lai, Jim Hagekyriakou, Sally Lightowler, Koishi Shudo, Matthias Ernst, Prof David Ashley, Jennifer L Short, Dr Greg Wheeler, Robert G Ramsay

(2012), Vol. 1, pp. 469-479, Stem cells translational medicine, Durham, N. C., C1-1



Industry and Other Funding

Can targeting lipid metabolism inhibit prostate cancer progression?

Dr Delphine Denoyer

  • 2016: $29,000


No completed student supervisions to report