AsPr Fred Pfeffer

STAFF PROFILE

Position

Associate Professor of Chemistry

Faculty

Faculty of Sci Eng & Built Env

Department

School of Life & Env. Sciences

Campus

Geelong Waurn Ponds Campus

Qualifications

Bachelor of Science, Deakin University, 1996
Doctor of Philosophy, Deakin University, 2001

Contact

fred.pfeffer@deakin.edu.au
+61 3 522 71439

Biography

Dr Pfeffer received his PhD from Deakin University in 2001.  He then spent a year lecturing at Trinity College Dublin (TCD) then a further 14 months at TCD as a postdoctoral research fellow working with Professor Thorfinnur Gunnlaugsson on the synthesis and evaluation of fluorescent anion sensors. 

Dr Pfeffer returned to Deakin in 2004 to the faculty of Science and Technology as a lecturer and was appointed senior Lecturer in 2009.  He continues to pursue research in the field of supramolecular anion recognition chemistry but has also developed several successful medicinal chemistry programs including the synthesis of new antibiotics, anticancer agents and also insulin sensitising antidiabetic agents.  At the core of these programs is the appreciation and understanding of how molecules interact and interconvert—fundamental topics in chemistry.

As at Aug 2015 he has >60 peer reviewed publications, over 2500 citations and a H-index of 21.

Read more on Fred's profile

Research interests

Supramolecular chemistry; in particular anion recognition and sensing using conformationally preorganised frameworks and metal assembled cages (collaboration with Prof Thorfinnur Gunnlaugsson from Trinity College Dublin-Ireland and also Prof Guido Clever from TU Dortmund - Germany)

Bioactive heterocycles as therapeutics and diagnostics (Collaboration with Dr Scott Stewart from UWA, Dr Sean McGee, Prof Ken Walder and Dr Guy Krippner from Verva)

Synthesis of new cationic amphiphilies as antimicrobial peptide mimics (collaboration with Prof Roger Nation and Dr Jian Li at Monash MIPS and also Prof Matthew Cooper and Dr Alysha Elliot from University of Queensland)

Recent grants include:

Discovery DP140100227 Novel Synthetic Receptors for Recognition and Transport of Biologically Important Anions

MRCF (Medical Research Commercialisation Fund) Rapid development of
new antidiabetic agents.

Linkage Infrastructure LE120100213 Advanced Fluorescence Characterisation Facility

Linkage LP100100087 Discovery and development of novel insulin sensitising compounds for the treatment of Type 2 diabetes.

Affiliations

RACI (Royal Australian Chemical Institute)

ACS (American Chemical Society)

RSC (Royal Society of Chemistry)

Teaching interests

Synthetic Organic and Medicinal Chemistry

Units taught

SLE155, SLE210, SLE214, SLE318, SLE313, SLEhons(chem)

Knowledge areas

Organic Chemistry

Supramolecular Chemistry

Medicinal Chemistry

Publications

No publications found

Grants

Australian Competitive Grants

Innovative Technology for At-Scene Forensic Analysis using Microfluidics and Chemiluminescence

Prof Neil Barnett, A/Prof Simon Lewis, A/Prof Fred Pfeffer, Prof Peter Fielden, Dr Gillian Greenway

ARC Linkage - Projects Rnd 1

  • 2008: $76,321
  • 2007: $72,265
  • 2006: $68,324

Discovery and development of novel insulin sensitising compounds for the treatment of Type 2 diabetes

Prof Ken Walder, A/Prof Fred Pfeffer, Dr Nicky Konstantopoulos, Dr Guy Krippner

ARC Linkage - Projects Rnd 1

  • 2012: $139,973
  • 2011: $88,130
  • 2010: $86,763

Biomolecular applications of supramolecular anion recognition chemistry

Prof Katrina Jolliffe, A/Prof Fred Pfeffer, Prof Philip Gale, Prof Thorfinnur Gunnlaugsson

ARC - Discovery Projects

  • 2016: $55,000
  • 2015: $55,000
  • 2014: $55,000

Other Public Sector Funding

Innovative Technology for At-Scene Forensic Analysis using Microfluidics and Chemiluminescence

Prof Neil Barnett, A/Prof Simon Lewis, A/Prof Fred Pfeffer, Prof Peter Fielden, Dr Gillian Greenway

  • 2008: $33,000
  • 2007: $33,500
  • 2006: $33,500

Industry and Other Funding

Discovery and development of novel insulin sensitising compounds for the treatment of Type 2 diabetes

Prof Ken Walder, A/Prof Fred Pfeffer, Dr Nicky Konstantopoulos, Dr Guy Krippner

  • 2012: $127,200
  • 2011: $174,725
  • 2010: $146,043

Supervisions

Principal Supervisor
2017

Ryan Robson

Thesis entitled: Further supramolecular chemistry of fused [n]polynorbornanes in solution and solid-state

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

2015

Shane Matthew Hickey

Thesis entitled: Norbornane-based Peptidomimetics as Antibacterial Agents

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

Cassandra Fleming

Thesis entitled: Development of Fluorescent and Class Selective HDAC Inhibitors

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

2014

Mark Johnstone

Thesis entitled: Conformationally preorganised hosts for Anion recognition and Sensing

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

Simren Kaur Khosa

Thesis entitled: Peptide Mimics Targeting Bacterial Membranes

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

Benjamin Long

Thesis entitled: Understanding and Applying Fused [n]Polynorbornane Scaffolds in Supramolecular Chemistry

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2013

Megan Thornton

Thesis entitled: SYNTHESIS OF FLAVONOIDS AND FLAVONOID-BASED DESIGNED MULTIPLE LIGANDS FOR HYPERTENSION

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2011

Daniel Priebbenow

Thesis entitled: A Novel Palladium-Catalysed Approach to Functionalised N-Heterocycles

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2010

Adam Lowe

Thesis entitled: Norbornenes and [n]Polynorbornanes as Molecular Scaffolds for Anion Recognition

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Marianne Seter

Thesis entitled: Novel Routes to Chiral Rings and Cages

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2007

Naomi Anne Lewcenko

Thesis entitled: The Design and Evaluation of Two Types of Chemical Sensor

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Associate Supervisor
2016

Jarrad Altimari

Thesis entitled: Investigations into 1,2,3-Triazoles for use in Medicinal Chemistry

Doctor of Philosophy (Life & Env), Institute for Frontier Materials

2014

Rebecca Waite

Thesis entitled: Chemiluminescence from reactions of tris(2,2¿-bipyridyl)ruthenium(III) with benzyl and phenylpiperazines

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2013

Joshua Delaney

Thesis entitled: The Synthesis and Evaluation of Novel, C2-Symmetric Organocatalysts

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

2012

Christopher Hindson

Thesis entitled: Mechanisms of Light Producing Chemical Reactions

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2010

Sara Ann Bellomarino

Thesis entitled: The Determination of Bioactive Compounds using HPLC with Chemiluminescence Detection

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Stephen Moran

Thesis entitled: Setting the Foundation for Molecular Nuts and Bolts

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2008

Shona Clark

Thesis entitled: Innovative Analytical Chemistry for Monitoring Wine Producation

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Jacqui Adcock

Thesis entitled: Applications and Fundamental understanding of Selected Analytically important Chemiluminescence Reactions

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2007

Richard Foitzik

Thesis entitled: Novel Conducting Polymer Films and Coated Textiles

Doctor of Philosophy (Engineering), Institute for Frontier Materials