Prof Kevin Nicholas

STAFF PROFILE

Position

Visitor

Faculty

Instit for Frontier Materials

Department

Instit for Frontier Materials

Campus

Geelong Waurn Ponds Campus

Publications

Filter by

2017

Hormonal regulation of platypus Beta-lactoglobulin and monotreme lactation protein genes

Dr Ashwantha Enjapoori, A/Prof Christophe Lefevre, Prof Kevin Nicholas, Dr Julie Sharp

(2017), Vol. 242, pp. 38-48, General and comparative endocrinology, Amsterdam, The Netherlands, C1

journal
2016

Analysis of human breast milk cells: gene expression profiles during pregnancy, lactation, involution, and mastitic infection

Dr Julie Sharp, A/Prof Christophe Lefevre, Dr Ashalyn Watt, Prof Kevin Nicholas

(2016), Vol. 16, pp. 297-321, Functional and integrative genomics, Berlin, Germany, C1

journal

Coassembled nanostructured bioscaffold reduces the expression of proinflammatory cytokines to induce apoptosis in epithelial cancer cells

Mrs Rui Li, Mrs Sivapriya Pavuluri, Kiara Bruggeman, Dr Benjamin Long, Andrew Parnell, Anne Martel, Steven Parnell, A/Prof Fred Pfeffer, Andrew Dennison, Prof Kevin Nicholas, Prof Colin Barrow, David R. Nisbet, Dr Richard Williams

(2016), Vol. 12, pp. 1397-1407, Nanomedicine: nanotechnology, biology and medicine, Amsterdam, The Netherlands, C1

journal
2015

Role of marsupial tammar wallaby milk in lung maturation of pouch young

Mr Venky Modepalli, Lyn Hinds, Dr Julie Sharp, A/Prof Christophe Lefevre, Prof Kevin Nicholas

(2015), Vol. 15, pp. -, BMC Developmental Biology, , C1

journal

Bioactive functions of milk proteins: a comparative genomics approach

Dr Julie Sharp, Mr Vengama Naidu Modepalli, Dr Ashwantha Enjapoori, Miss Swathi Bisana, Helen Abud, A/Prof Christophe Lefevre, Prof Kevin Nicholas

(2015), Vol. 19, pp. 289-302, Journal of mammary gland biology and neoplasia, Berlin, Germany, C1

journal
2014

Comparative analysis of caveolins in mouse and tammar wallaby: role in regulating mammary gland function.

Miss Sanjana Kuruppath, Dr Julie Sharp, A/Prof Christophe Lefevre, Robyn M. Murphy, Prof Kevin Nicholas

(2014), Vol. 552, pp. 51-58, Gene, Amsterdam , Netherlands, C1

journal

Differential temporal expression of milk miRNA during the lactation cycle of the marsupial tammar wallaby (Macropus eugenii)

Mr Venky Modepalli, Mr Amit Kumar, Lyn Hinds, Dr Julie Sharp, Prof Kevin Nicholas, A/Prof Christophe Lefevre

(2014), Vol. 15, pp. 1-17, BMC genomics, London, England, C1

journal

Monotreme lactation protein is highly expressed in monotreme milk and provides antimicrobial protection

Dr Ashwantha Enjapoori, Tom R Grant, Stewart C Nicol, A/Prof Christophe Lefevre, Prof Kevin Nicholas, Dr Julie Sharp

(2014), Vol. 6, pp. 2754-2773, Genome biology and evolution, Oxford, England, C1

journal

In vitro response to functionalized self-assembled peptide scaffolds for three-dimensional cell culture

Mr Vengama Naidu Modepalli, Alexandra L Rodriguez, Mrs Rui Li, Mrs Sivapriya Pavuluri, Prof Kevin Nicholas, Prof Colin Barrow, David R. Nisbet, Dr Richard Williams

(2014), Vol. 102, pp. 197-205, Biopolymers peptide science, Hoboken, NJ, C1

journal

Expansion of human hematopoietic stem/progenitor cells on decellularized matrix scaffolds

Dr Abhilasha Tiwari, A/Prof Christophe Lefevre, Prof Mark Kirkland, Prof Kevin Nicholas

(2014), Vol. 28, pp. 1-1, Current protocols in stem cell biology, London, Eng., C1

journal

Molecular genetics of milk protein production

Dr Julie Sharp, Prof Kevin Nicholas

(2014), pp. 397-432, The genetics of cattle, Wallingford, Eng., B1

chapter
2013

Transcriptome analysis of pigeon milk production - role of cornification and triglyceride synthesis genes

Meagan Gillespie, Dr Tamsyn Crowley, Volker R. Haring, Susanne L. Wilson, Jennifer Harper, Jean S. Payne, Diane Green, Dr Paul Monaghan, Prof John Donald, Prof Kevin Nicholas, R.J. Moore

(2013), Vol. 14, pp. 1-12, BMC genomics, London, England, C1

journal

Identification and functional characterization of a novel monotreme - specific antibacterial protein expressed during lactation

Miss Swathi Bisana, Dr Satish Kumar, Peggy Rismiller, Stewart C Nicol, A/Prof Christophe Lefevre, Prof Kevin Nicholas, Dr Julie Sharp

(2013), Vol. 8, pp. 1-12, PLoS one, San Francisco, Calif., C1

journal

The extracellular matrix regulates MaeuCath1a gene expression

Mr Stephen Wanyonyi, A/Prof Christophe Lefevre, Dr Julie Sharp, Prof Kevin Nicholas

(2013), Vol. 40, pp. 289-299, Developmental and comparative immunology, Amsterdam, The Netherlands, C1

journal

Lactating fur seal case study suggests miR21 may contribute to mammary gland involution evasion during off-shore lactation via regulation of PTEN

Ms Laurine Buscara, Mr Amit Kumar, Dr Julie Sharp, Prof Kevin Nicholas, A/Prof Christophe Lefevre

(2013), Vol. 1, pp. 5-8, Asian journal of animal research, Kerala, India, C1

journal

Molecular evolution of a novel marsupial S100 protein (S100A19) which is expressed at specific stages of mammary gland and gut development

Joly Kwek, Ms Alicia Wynne, A/Prof Christophe Lefevre, Mary Familari, Prof Kevin Nicholas, Dr Julie Sharp

(2013), Vol. 69, pp. 4-16, Molecular phylogenetics and evolution, Amsterdam, The Netherlands, C1

journal

The extracellular matrix locally regulates asynchronous concurrent lactation in tammar wallaby (Macropus eugenii)

Mr Stephen Wanyonyi, A/Prof Christophe Lefevre, Dr Julie Sharp, Prof Kevin Nicholas

(2013), Vol. 32, pp. 342-351, Matrix biology, Amsterdam, The Netherlands, C1

journal

Comparative gene expression profiling of stromal cell matrices that support expansion of hematopoietic stem/progenitor cells.

Dr Abhilasha Tiwari, A/Prof Christophe Lefevre, Prof Mark Kirkland, Prof Kevin Nicholas, Dr Gopal Pande

(2013), Vol. 3, pp. 1-15, Stem cell research & therapy, London, England, C1

journal
2012

The tammar wallaby : a model system to examine domain-specific delivery of milk protein bioactives

Prof Kevin Nicholas, Dr Julie Sharp, Dr Ashalyn Watt, Mr Stephen Wanyonyi, Dr Tamsyn Crowley, Meagan Gillespie, A/Prof Christophe Lefevre

(2012), Vol. 23, pp. 547-556, Seminars in cell and developmental biology, London, England, C1

journal

Monotremes and marsupials : comparative models to better understand the function of milk

Miss Sanjana Kuruppath, Miss Swathi Bisana, Dr Julie Sharp, A/Prof Christophe Lefevre, Dr Satish Kumar, Prof Kevin Nicholas

(2012), Vol. 37, pp. 581-588, Journal of biosciences, Karnataka, India, C1

journal

WFDC2 is differentially expressed in the mammary gland of the tammar wallaby and provides immune protection to the mammary gland and the developing pouch young

Dr Ashalyn Watt, Dr Julie Sharp, A/Prof Christophe Lefevre, Prof Kevin Nicholas

(2012), Vol. 36, pp. 584-590, Developmental and comparative immunology, Oxford, U. K., C1

journal

Controlling wettability of boron nitride nanotube films and improved cell proliferation

Ling Li, Dr Luhua Li, Miss Sugeetha Ramakrishnan, Dr Jane Dai, Prof Kevin Nicholas, Prof Ying (Ian) Chen, Dr Zhiqiang Chen, Xiaowei Liu

(2012), Vol. 116, pp. 18334-18339, Journal of physical chemistry C, Washington, D. C., C1

journal

Functional similarities between pigeon 'milk' and mammalian milk : induction of immune gene expression and modification of the microbiota

Meagan Gillespie, Dragana Stanley, Honglei Chen, Prof John Donald, Prof Kevin Nicholas, R.J. Moore, Dr Tamsyn Crowley

(2012), Vol. 7, pp. 1-10, PLoS one, San Francisco, Calif., C1

journal
2011

Conservation of the ST6Gal I gene and its expression in the mammary gland

Ms Jovana Maksimovic, Dr Julie Sharp, Prof Kevin Nicholas, Benjamin G. Cocks, Keith Savin

(2011), Vol. 21, pp. 467-481, Glycobiology, Cary, N. C., C1

journal

Acute involution in the tammar wallaby : identification of genes and putative novel milk proteins implicated in mammary gland function

elie khalil, Matthew Digby, Peter Campbell Thomson, A/Prof Christophe Lefevre, Sonia L. Mailer, Ms Cathryn Laurelle Pooley, Prof Kevin Nicholas

(2011), Vol. 97, pp. 372-378, Genomics, Maryland Heights, Mo., C1

journal

Tammar wallaby mammary cathelicidins are differentially expressed during lactation and exhibit antimicrobial and cell proliferative activity

Mr Stephen Wanyonyi, Dr Julie Sharp, elie khalil, A/Prof Christophe Lefevre, Prof Kevin Nicholas

(2011), Vol. 160, pp. 431-439, Comparative biochemistry and physiology. Part A : molecular & integrative physiology, New York, N. Y., C1

journal

Histological and global gene expression analysis of the ‘lactating’ pigeon crop

Meagan Gillespie, Volker R. Haring, Dr Kenneth McColl, Dr Paul Monaghan, Prof John Donald, Prof Kevin Nicholas, R.J. Moore, Dr Tamsyn Crowley

(2011), Vol. 12, pp. 1-9, BMC genomics, London England, C1

journal
2010

Marsupial milk : identifying signals for regulating mammary function and development of the young

Dr Julie Sharp, A/Prof Christophe Lefevre, Joly Kwek, Denijal Topcic, Ms Laurine Buscara, Ms Cathryn Laurelle Pooley, Robb de Iongh, Mary Familari, Prof Kevin Nicholas

(2010), pp. 317-334, Marsupial genetics and genomics, Dordrecht, The Netherlands, B1

chapter

Evolution of lactation : ancient origin and extreme adaptations of the lactation system

A/Prof Christophe Lefevre, Dr Julie Sharp, Prof Kevin Nicholas

(2010), Vol. 11, pp. 219-238, Annual review of genomics and human genetics, Palo Alto, Calif., C1

journal

Insulin, a key regulator of hormone responsive milk protein synthesis during lactogenesis in murine mammary explants

Ms Karensa Menzies, Heather J. Lee, A/Prof Christophe Lefevre, Christopher J Ormandy, Keith L. Macmillan, Prof Kevin Nicholas

(2010), Vol. 10, pp. 87-95, Functional and integrative genomics, Heidelberg, Germany, C1

journal

Blood plasma concentrations of metabolic hormones and glucose during extended lactation in grazing cows or cows fed a total mixed ration

K. K. Delany, Keith L. Macmillan, C. Grainger, P.C Thomson, D. Blache, Prof Kevin Nicholas, M. J. Auldist

(2010), Vol. 93, pp. 5913-5920, Journal of dairy science, New York, N.Y., C1-1

journal
2009

Characterisation of monotreme caseins reveals lineage-specific expansion of an ancestral casein locus in mammals

A/Prof Christophe Lefevre, Dr Julie Sharp, Prof Kevin Nicholas

(2009), Vol. 21, pp. 1015-1027, Reproduction, fertility and development, Collingwood, Vic., C1

journal

A novel approach identified the FOLR1 gene, a putative regulator of milk protein synthesis

Ms Karensa Menzies, A/Prof Christophe Lefevre, Dr Julie Sharp, Keith L. Macmillan, Paul A. Sheehy, Prof Kevin Nicholas

(2009), Vol. 20, pp. 498-503, Mammalian genome, New York, N. Y., C1

journal

The comparative genomics of tammar wallaby and Cape fur seal lactation models to examine function of milk proteins.

Dr Julie Sharp, Matthew Digby, A/Prof Christophe Lefevre, Sonia L. Mailer, elie khalil, Denijal Topcic, Aurelie Auguste, Joly Kwek, Amelia Brennan, Mary Familari, Prof Kevin Nicholas

(2009), pp. 55-79, Milk proteins : from expression to food, San Diego, Calif., B1-1

chapter

Significance, origin and function of bovine milk proteins : the biological implications of manipulation or modification

Paul A. Sheehy, P. Williamson, Dr Julie Sharp, Ms Karensa Menzies, A/Prof Christophe Lefevre, Matthew Digby, Prof Kevin Nicholas, P. C. Wynn

(2009), pp. 81-106, Milk proteins : from expression to food, San Diego, Calif., B1-1

chapter
2008

MammoSapiens: eResearch of the lactation program.

Prof Kevin Nicholas, Mr Amit Kumar, Yvan Strahm, David Powell, Torsten Seemann, Kerry A. Daly, Amelia Brennan, Ms Karensa Menzies, Dr Julie Sharp, Matthew Digby, A/Prof Christophe Lefevre

(2008), pp. 1-13, Proceedings of eResearch Australasia 2008, Australia, E1

conference

Lack of functional alpha-lactalbumin prevents involution in Cape fur seals and identifies the protein as an apoptotic milk factor in mammary gland involution

Dr Julie Sharp, A/Prof Christophe Lefevre, Prof Kevin Nicholas

(2008), Vol. 6, pp. 1-15, BMC biology, London, England, C1

journal

Uncoupling the mechanisms that facilitate cell survival in hormone-deprived bovine mammary explants

Amelia Brennan, Dr Julie Sharp, A/Prof Christophe Lefevre, Prof Kevin Nicholas

(2008), Vol. 41, pp. 103-116, Journal of molecular endocrinology, Bristol, England, C1-1

journal
2007

The fur seal — a model lactation phenotype to explore molecular factors involved in the initiation of apoptosis at involution

Dr Julie Sharp, A/Prof Christophe Lefevre, Amelia Brennan, Prof Kevin Nicholas

(2007), Vol. 12, pp. 47-58, Journal of mammary gland biology and neoplasia, New York, N.Y., C1-1

journal
2006

Species-specific cell-matrix interactions are essential for differentiation of alveoli like structures and milk gene expression in primary mammary cells of the Cape fur seal (Arctocephalus pusillus pusillus)

Dr Julie Sharp, Kylie. N. Cane, Sonia L. Mailer, Mr Herman Oosthuizen, Prof John Arnould, Prof Kevin Nicholas

(2006), Vol. 25, pp. 430-442, Matrix biology, Amsterdam, The Netherlands, C1

journal
2005

Fur seal adaptations to lactation: insights into mammary gland function

Dr Julie Sharp, Kylie. N. Cane, A/Prof Christophe Lefevre, Prof John Arnould, Prof Kevin Nicholas

(2005), Vol. 72, pp. 275-308, Current topics in developmental biology, Boston, Mass., C1

journal

Characterisation of proteins in the milk of fur seals

Kylie. N. Cane, Prof John Arnould, Prof Kevin Nicholas

(2005), Vol. 141, pp. 111-120, Comparative biochemistry and physiology. part B: biochemistry and molecular biology, Boston, Mass., C1

journal

The lactation cycle of the fur seal

Dr Julie Sharp, Kylie. N. Cane, Prof John Arnould, Prof Kevin Nicholas

(2005), Vol. 72, pp. 81-89, Journal of dairy research, Cambridge, England, C1

journal

Grants

Australian Competitive Grants

High value dairy component development - ALAC therapeutic applications

Prof Kevin Nicholas

Dairy Australia Limited

  • 2012: $8,750
  • 2010: $26,250
  • 2009: $85,000

DU13194 The characterisation and application of an apoptotic milk component.

Prof Kevin Nicholas

Dairy Australia Limited

  • 2011: $9,375
  • 2010: $28,125
  • 2009: $177,500

Industry and Other Funding

A new approach to identify proteins to improve gut development and function in low birth weight babies

Prof Kevin Nicholas

  • 2011: $99,932

Supervisions

Principal Supervisor
2014

Swathi Bisana

Thesis entitled: Evolution of Mammary Gland Function: A study using Monotreme Models

Doctor of Philosophy (Medicine), School of Medicine

Alicia Wynne

Thesis entitled: Characterisation of an Ancient S100 Protein with Multiple Functions

Doctor of Philosophy (Medicine), School of Medicine

Sanjana Kuruppath

Thesis entitled: Programmed function of the tammar mammary gland; The role of Milk Proteins in gut development.

Doctor of Philosophy (Medicine), School of Medicine

2013

Stephen Wanyonyi

Thesis entitled: Paracrine control of milk protein gene expression in tammar wallaby

Doctor of Philosophy (Medicine), School of Medicine

Laurine Buscara

Thesis entitled: Fur seal mammary gland evasion of involution and cell-matrix interactions

Doctor of Philosophy (Biol & Chem), BioDeakin

2012

Abhilasha Tiwari

Thesis entitled: Replication of the Hematopoietic Stem Cell Niche

Doctor of Philosophy (Life & Env), BioDeakin

Associate Supervisor
2013

Meagan Gillespie

Thesis entitled: Transcriptomic characterisation of pigeon 'milk' production and its effect on young

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences