Dr Kislay Roy

STAFF PROFILE

Position

Alfred Deakin Post Doctoral Research Fellow

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Qualifications

Bachelor of Science, Bangalore University, 2007
Master of Science in Applied Microbiology, Vellore Institute of Tech Uni, 2009
Doctor of Philosophy, Deakin University, 2014

Career highlights

My most significant achievements are:
1. Awarded the Deakin University International Postgraduate Research Scholarship (DUIPR) in the year 2010 for studying Doctor of Philosophy at Deakin University, Australia
2. Awarded with Trade and Investment PhD Student Researcher Award for excellence in nanomedicine research for best poster presentation at the Sydney International Nanomedicine Conference, Coogie Beach, 2011.
3. Awarded with Doctor of Philosophy, Deakin University, Australia on 9/10/2014.
4. Awarded with the position of Research Fellow at School of Medicine, Deakin University, Australia on 18/11/2013.
5. Awarded with the Best Speaker award at the 2nd International Conference on Biotechnology and Pharmaceutical Sciences (Brightice), Hyderabad, India on 3-4th August 2015.

Research interests

The main focus of my research is development of multi-targeted oral or intravenous delivery systems for treatment and diagnosis of cancer. I synthesized cancer stem cell targeted; locked nucleic acid (LNA) decorated smart nanocarriers for effective oral delivery of colon cancer. I was also the first to combine the anti-cancer therapeutic effects of emerging biodrug bovine lactoferrin with the multimodal imaging efficacy of superparamagnetic iron oxide nanoparticles (SPIONs) and successfully achieve synergism in the imaging capabilities of live tumour monitoring and treatment efficacy using magnetic resonance imaging (MRI), computerized tomography (CT) and near infra-red imaging (NIR) techniques.

Conferences

1. 2nd International conference on Biotechnology and Pharmaceutical Sciences 2015
Held at Hyderabad, India
2. Sydney International Nanomedicine conference 2011, 2012 and 2013
Held at Coogie beach, Sydney, Australia
3. Symposium Biofutura 2005
Held at CMR Institute of Technology, Bangalore, India
4. Annual IFM conference 2010, 2011 and 2012
Held at Geelong, Australia
5. National Lecture Workshop on “Trends in Medical Biotechnology” 2008
Held at Vellore Institute of Technology University, Vellore, India

Awards

1. Awarded with Best Speaker award at 2nd International conference on biotechnology and pharmaceutical sciences (Brightice), Hyderabad, India 2015.
2. Awarded with the position of Research Fellow at School of Medicine, Deakin University, Australia on 18/11/2013.
3. Awarded with Doctor of Philosophy, Deakin University, Australia, 2014.
4. Awarded the Deakin University Publication Scholarship, 2013.
5. Awarded with Trade and Investment Ph.D. Student Researcher Award for excellence in nanomedicine research, Sydney International Nanomedicine Conference, 2011.
6. Awarded with Deakin University Post graduate International Research Scholarship for a P.hD course, 2010.
7. Awarded Scholarship from VIT University, Vellore to conduct research training in University of Maribor, Slovenia, 2009.
8. Awarded with “Best Male outgoing Student” in Garden City College, Bangalore University, India, 2007.

Publications

Filter by

2017

Topical ophthalmic formulation of Trichostatin A and SurR9-C84A for quick recovery post-alkali burn of corneal haze

K Roy, C Cheung, R Kanwar, R Sandhir, J Kanwar

(2017), Vol. 8, pp. 1-15, Experimental pharmacology and drug discovery, Lausanne, Switzerland, C1

journal
2016

Biodegradable Eri silk nanoparticles as a delivery vehicle for bovine lactoferrin against MDA-MB-231 and MCF-7 breast cancer cells

K Roy, Y Patel, R Kanwar, R Rajkhowa, X Wang, J Kanwar

(2016), Vol. 11, pp. 25-44, International journal of nanomedicine, Macclesfield, Eng., C1

journal

Engineered atherosclerosis-specific zinc ferrite nanocomplex-based MRI contrast agents

R Chaudhary, K Roy, R Kanwar, K Walder, J Kanwar

(2016), Vol. 14, pp. 1-17, Journal of nanobiotechnology, London, Eng., C1

journal

Comparative activities of milk components in reversing chronic colitis

J Kanwar, R Kanwar, S Stathopoulos, N Haggarty, A MacGibbon, K Palmano, K Roy, A Rowan, G Krissansen

(2016), Vol. 99, pp. 2488-2501, Journal of dairy science, Atlanta, Ga., C1

journal

Survivin modulators: an updated patent review (2011-2015)

K Roy, N Singh, R Kanwar, J Kanwar

(2016), Vol. 11, pp. 152-169, Recent patents on anti-cancer drug discovery, Beijing, China, C1

journal

Theranostic multimodular potential of zinc-doped ferrite-saturated metal-binding protein-loaded novel nanocapsules in cancers

S Kamalapuram, R Kanwar, K Roy, R Chaudhary, R Sehgal, J Kanwar

(2016), Vol. 11, pp. 1349-1366, International journal of nanomedicine, Macclesfield, Eng., C1

journal

Ophthalmic combination of SurR9-C84A and trichostatin-A targeting molecular pathogenesis of alkali burn

K Roy, B Sriramoju, R Kanwar, J Kanwar

(2016), Vol. 7, pp. 1-14, Frontiers in Pharmacology, Lausanne, Switzerland, C1

journal

E-cadherin aptamer-conjugated delivery of doxorubicin for targeted inhibition of prostate cancer cells

R Chaudhary, K Roy, R Kanwar, R Veedu, S Krishnakumar, C Cheung, A Verma, J Kanwar

(2016), Vol. 69, pp. 1108-1116, Australian journal of chemistry, Clayton, Vic., C1

journal
2015

Fe-bLf nanoformulation targets survivin to kill colon cancer stem cells and maintains absorption of iron, calcium and zinc

J Kanwar, V Mahidhara, K Roy, S Sasidharan, S Krishnakumar, N Prasad, R Sehgal, R Kanwar

(2015), Vol. 10, pp. 35-55, Nanomedicine, London, United Kingdom, C1

journal

Competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model

K Roy, R Kanwar, S Krishnakumar, C Cheung, J Kanwar

(2015), Vol. 10, pp. 1019-1043, International journal of nanomedicine, Auckland, N. Z., C1

journal

Nucleic acid-based aptamers: applications, development and clinical trials

J Kanwar, K Roy, N Maremanda, K Subramanian, R Veedu, R Bawa, R Kanwar

(2015), Vol. 22, pp. 2539-2557, Current medicinal chemistry, Bussum, The Netherlands, C1

journal

Evaluation of nanoformulated therapeutics in an ex-vivo bovine corneal irritation model

B Sriramoju, K Roy, R Kanwar, J Kanwar

(2015), Vol. 29, pp. 917-925, Toxicology in vitro, Amsterdam, The Netherlands, C1

journal

Locked nucleic acid modified bi-specific aptamer-targeted nanoparticles carrying survivin antagonist towards effective colon cancer therapy

K Roy, R Kanwar, C Antonio Cheung, C Lee Fleming, R Veedu, S Krishnakumar, J Kanwar

(2015), Vol. 5, pp. 29008-29016, RSC advances, Cambridge, Eng., C1

journal

Multifunctional iron bound lactoferrin and nanomedicinal approaches to enhance its bioactive functions

J Kanwar, K Roy, Y Patel, S-F Zhou, M Singh, D Singh, M Nasir, R Sehgal, A Sehgal, R Singh, S Garg, R Kanwar

(2015), Vol. 20, pp. 9703-9731, Molecules, Basel, Switzerland, C1-1

journal

Targeting VEGF with LNA-stabilized G-rich oligonucleotide for efficient breast cancer inhibition

S Edwards, V Poongavanam, J Kanwar, K Roy, K Hillman, N Prasad, R Leth-Larsen, M Petersen, M Maru?i?, J Plavec, J Wengel, R Veedu

(2015), Vol. 51, pp. 9499-9502, Chemical Communications, London, Eng., C1

journal

Oral administration of iron-saturated bovine lactoferrin-loaded ceramic nanocapsules for breast cancer therapy and influence on iron and calcium metabolism

G Mahidhara, R Kanwar, K Roy, J Kanwar

(2015), Vol. 10, pp. 4081-4098, International journal of nanomedicine, Auckland, N. Z., C1

journal

LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging

K Roy, R Kanwar, J Kanwar

(2015), Vol. 71, pp. 84-99, Biomaterials, Amsterdam, The Netherlands, C1

journal

Molecular targets in arthritis and recent trends in nanotherapy

K Roy, R Kanwar, J Kanwar

(2015), Vol. 10, pp. 5407-5420, International journal of nanomedicine, Auckland, N. Z., C1

journal

Quick chip assay using locked nucleic acid modified epithelial cell adhesion molecule and nucleolin aptamers for the capture of circulating tumor cells

N Maremanda, K Roy, R Kanwar, V Shyamsundar, V Ramshankar, A Krishnamurthy, S Krishnakumar, J Kanwar

(2015), Vol. 9, pp. 1-20, Biomicrofluidics, Maryland, United States, C1

journal
2014

Bioceramic nanomaterials in medical applications

J Kanwar, G Mahidhara, K Roy, R Kanwar

(2014), pp. 163-175, Bioengineered nanomaterials, Boca Raton, Flo., B1

chapter
2011

Chimeric aptamers in cancer cell-targeted drug delivery

J Kanwar, K Roy, R Kanwar

(2011), Vol. 46, pp. 459-477, Critical reviews in biochemistry and molecular biology, London, England, C1

journal
2010

Applications of aptamers in nanodelivery systems in cancer, eye and inflammatory diseases

J Kanwar, R Mohan, R Kanwar, K Roy, R Bawa

(2010), Vol. 5, pp. 1435-1445, Nanomedicine, London, England, C1

journal

Funded Projects at Deakin

No Funded Projects at Deakin found

Supervisions

No completed student supervisions to report