Biography
After completing postgraduate studies at the Murdoch Childrens’ Research Institute (University of Melbourne), I commenced employment at Deakin University at the Rusden Campus in 1994. At that time at the Melbourne campuses there were no facilities for research in laboratory-based biology. I established the first biology research laboratory and initiated laboratory-based research at Rusden. In 2000, the Rusden laboratory was transformed into the Centre for Cellular and Molecular Biology (CCMB) at the Burwood campus. At its inception, the CCMB was focussed on metal biology in relation to humans. Since leading research in this facility from 2013, I have broadened its focus on metals to include research on plants, fungi, algae and bacteria, and introduced other aspects of human-based molecular biology including cancer and diabetes. This has been achieved by strategic appointments of new staff with a range of skills and experience. As deputy director of the Molecular and Medical Strategic Research Centre I have played a key role in building collaborations within and outside the university in the human bioscience discipline. My supervision of PhD students has been a major factor in facilitating the building of research projects and teams.
Read more on Leigh's profileCareer highlights
My most outstanding career highlight was to be conferred an Alfred Deakin Professor in 2018, for outstanding and sustained contribution to furthering Deakin's research and teaching, and the highest honour the University can bestow on a member of the academic staff.
In 2014 I was one of 26 international leading scientists invited to participate in the Ernst Strungman forum in Frankfurt, Germany to address key gaps in knowledge in global issues relating to Heavy Metals and Infectious Diseases, and in 2007 the Australian Governmen nominated me as one of 10 scientists to participate in the Indo-Australia Bioremediation Conference in Delhi, India.
Contribution to inquiry into Biofuels in the State Parliament of Victoria, 2007.
Over the last ten years I have played key roles in establishing international programs between Deakin University and universites in China and India, including the Chinese-Australian Joint Research Centre for Environmental Remediation and Health with the Chinese Academy of Science), and Deakin-TERI nanotechology programme in India.
In the last three years I have been successful in attracting major NHMRC and philanthropic funding for research into neuroendocrine tumors.
Invited Reviews
Ackland ML, Michalczyk AA. Invited Review. Zinc and infant nutrition. Arch Biochem Biophys. 2016 Jun 15. pii: S0003-9861(16)30197-7.
Hugo H, Ackland ML, Lawrence M, Clements J, Williams JD, Thompson EW. 2007. Epithelial - Mesenchymal and Mesenchymal - Epithelial Transitions in Solid Carcinoma Progression. J Cell Physiol 75th Aniversary Issue Invited Review 213 (2):374-83.
Ackland M L and Michalczyk A. Zinc deficiency and its inherited disorders – A review. 2006 Genes and Nutrition 1:41-50.
Research interests
Identifcation of novel markers to assist in improved detection and treatment of gastrointestinal neuroendocrine carcinomas and investigtion of drug resistance.
Multifunctional and environmentally friendly corrosion inhibitor systems.
Epigenetic factors that underlie the pathology of type 2 diabetes during pregnancy.
Molecular biology of zinc and copper in human diseases to understand zinc and copper fluxes in cells and elucidation of inherited disorders in humans that result in the production of trace element-deficient milk during lactation.
Mechanisms underlying the spread of breast and neuroendocrine cancers termed “epithelial to mesenchymal transition” to understand why cancer cells metastasise
How nanoliposome can be used to deliver omega-3 fatty acids to brain cells.
Development of remediation strategies for heavy metal-contaminated soils and water.
Molecular basis of heavy metal tolerance in bacteria, fungi and plants.
Teaching interests
Introducing an understanding of the experimental basis of science and how research has shaped our understanding of biology
Knowledge areas
Cell and molecular biology and epigenetic processes in human disorders including cancers and type 2 diabetes, the biology of trace elements and heavy metals in bacteria, fungi, plants and animals
Projects
Currently funded projects
Molecular proflling of of Gastrointestinal Neuroendocrine Carcinomas”. NHMRC Project APP1102018, $1,393,082.86 in 2016 and Bourne Foundation funding $000,000 in 2019.
Multifunctional and environmentally friendly corrosion inhibitor systems. ARC-DP180101465. $392,952 in 2018
Epigenetic factors in Diabetes. Greater Green Triangle, University of Melbourne $45,000 in 2016.With a team of clinicians, we are investigating changers in histone methylation that occur in diabetes during pregnancy.
Past projects
Molecular biology of zinc and copper in human diseases to understand zinc and copper fluxes in cells and elucidation of inherited disorders in humans that result in the production of trace element-deficient milk during lactation.
Mechanisms underlying the spread of breast cancer cells
Using a novel human breast cancer line we study the mechanisms of breast cancer metastasis termed “epithelial to mesenchymal transition”.
Nanoliposomal delivery of DHA to human neuronal cells. ARC Discovery Project- DP120101309. 2012-2014. $280,000.
Development of remediation strategies for heavy metal-contaminated soils and water.
Molecular basis of heavy metal tolerance in plants where field trials of selected plants were used to remediate cadmium-contaminated soils and to establish the cellular mechanisms that enable plants to accumulate or resist heavy metals.
Publications
J Puelles, M Ghorbani, B Tuck, L Machuca, M Ackland, F Chen, A Somers, M Forsyth
(2023), Vol. 13, pp. 1-13, Scientific Reports, London, Eng., C1
Modelling cetrimonium micelles as 4-OH cinnamate carriers targeting a hydrated iron oxide surface
J Soto Puelles, Mahdi Ghorbani, S Crawford, M Ackland, F Chen, M Forsyth, A Somers
(2022), Vol. 610, pp. 785-795, Journal of Colloid and Interface Science, Amsterdam, The Netherlands, C1
Inhibitor mixture for reducing bacteria growth and corrosion on marine steel
R Catubig, A Michalczyk, W Neil, G McAdam, J Forsyth, M Ghorbani, R Yunis, M Ackland, M Forsyth, A Somers
(2022), Vol. 75, pp. 619-630, Australian Journal of Chemistry, Melbourne, Vic., C1
U Shankar, S Lenka, M Ackland, D Callahan
(2022), Vol. 119, pp. 2031-2045, Biotechnology and Bioengineering, London, Eng., C1
EMT Molecular Signatures of Pancreatic Neuroendocrine Neoplasms
A Venugopal, A Michalczyk, M Khasraw, L Ackland
(2022), Vol. 23, pp. 1-23, International Journal of Molecular Sciences, Basel, Switzerland, C1
A Venugopal, J Gillick-Walker, A Michalczyk, M Khasraw, M Ackland
(2021), Vol. 21, BMC Gastroenterology, England, C1
Chromium tolerance and accumulation in Aspergillus flavus isolated from tannery effluent
Shilpi Vajpai, Philip Taylor, Alok Adholeya, M Ackland
(2020), Vol. 60, pp. 58-71, Journal of basic microbiology, London, Eng., C1
M Ghorbani, J Soto Puelles, M Forsyth, R Catubig, L Ackland, L Machuca, H Terryn, A Somers
(2020), Vol. 11, pp. 9886-9892, Journal of Physical Chemistry Letters, United States, C1
K Flynn, A Sutti, L Martin, M Leigh Ackland, A Torriero
(2018), Vol. 1860, pp. 1135-1142, Biochimica et Biophysica Acta - Biomembranes, Netherlands, C1
A Michalczyk, E Janus, A Judge, P Ebeling, J Best, M Ackland, D Asproloupos, J Dunbar, M Ackland
(2018), Vol. 10, pp. 419-431, Epigenomics, England, C1
Mechanism of docosahexaenoic acid in the enhancement of neuronal signalling
Bari, Gaburro, Michalczyk, Ackland, Catherine Williams, A Bhatti
(2017), pp. 99-117, Emerging trends in neuro engineering and neural computation, Singapore, B1
Selective metal ion homeostasis in cyanobacteria
L Hudek, M Ackland
(2017), pp. 219-232, Prospects and challenges in algal biotechnology, Singapore, Singapore, B1
Peroxide reduction by a metal-dependent catalase in Nostoc punctiforme (cyanobacteria)
L Hudek, A Torriero, A Michalczyk, B Neilan, M Ackland, L Bräu
(2017), Vol. 101, pp. 3781-3800, Applied Microbiology and Biotechnology, Germany, C1
Identifying Epithelial Endocytotic Mechanisms of the Peanut Allergens Ara h 1 and Ara h 2
D Price, M Ackland, C Suphioglu
(2017), Vol. 172, pp. 106-115, International Archives of Allergy and Immunology, Switzerland, C1
Identification and topographical characterisation of microbial nanowires in Nostoc punctiforme
S Sure, A Torriero, A Gaur, L Li, Y Chen, C Tripathi, A Adholeya, M Ackland, M Kochar
(2016), Vol. 109, pp. 475-480, Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology, Netherlands, C1
Epigenetic markers to predict conversion from gestational diabetes to type 2 diabetes
A Michalczyk, J Dunbar, E Janus, J Best, P Ebeling, M Ackland, D Asproloupos, M Ackland
(2016), Vol. 101, pp. 2396-2404, Journal of Clinical Endocrinology and Metabolism, United States, C1
M Ackland, A Michalczyk
(2016), Vol. 611, pp. 51-57, Archives of Biochemistry and Biophysics, United States, C1
D Freestone, D Denoyer, M Jakab, M Leigh Ackland, M Cater, A Michalczyk
(2016), Vol. 8, pp. 941-950, Metallomics, England, C1
Probing Synechocystis-arsenic interactions through extracellular nanowires
S Sure, M Ackland, A Gaur, P Gupta, A Adholeya, M Kochar
(2016), Vol. 7, Frontiers in Microbiology, Switzerland, C1
K Flynn, L Martin, M Ackland, A Torriero
(2016), Vol. 32, pp. 11717-11727, Langmuir, United States, C1
Microbial nanowires: An electrifying tale
S Sure, M Ackland, A Torriero, A Adholeya, M Kochar
(2016), Vol. 162, pp. 2017-2028, Microbiology (United Kingdom), England, C1
V Ahire, D Das, K Mishra, G Kulkami, M Ackland
(2016), Vol. 35, pp. 355-364, Journal of Environmental Pathology, Toxicology and Oncology, Danbury, CT, C1
Metals in the environment as risk factors for infectious diseases:Gaps and opportunities
M Ackland, J Bornhorst, G Dedoussis, R Dietert, J Nriagu, J Pacyna, J Pettifor
(2015), pp. 270-307, Trace metals and infectious diseases, Cambridge, Mass., B1
Lubricin: a versatile, biological anti-adhesive with properties comparable to polyethylene glycol
G Greene, L Martin, R Tabor, A Michalczyk, L Ackland, R Horn
(2015), Vol. 53, pp. 127-136, Biomaterials, Amsterdam, The Netherlands, C1
Characterization of two cation diffusion facilitators NpunF0707 and NpunF1794 in Nostoc punctiforme
L Hudek, L Pearson, A Michalczyk, L Brau, B Neilan, M Ackland
(2015), Vol. 119, pp. 1357-1370, Journal of applied microbiology, Weinheim, Germany, C1
L Hudek, L Brau, A Michalczyk, B Neilan, J Meeks, M Ackland
(2015), Vol. 99, pp. 10559-10574, Applied microbiology and biotechnology, New York, N.Y., C1
Inquisition of Microcystis aeruginosa and Synechocystis nanowires: characterization and modelling
S Sure, A Torriero, A Gaur, L Li, Y Chen, C Tripathi, A Adholeya, M Ackland, M Kochar
(2015), Vol. 108, pp. 1213-1225, Antonie van Leeuwenhoek: international journal of general and molecular microbiology, New York, N.Y., C1
L Kumar, A Michalczyk, J McKay, D Ford, T Kambe, L Hudek, G Varigios, P Taylor, M Ackland
(2015), Vol. 10, pp. 487-502, Genes and nutrition, New York, N.Y., C1
J Wadwa, Y Chu, N Nguyen, T Henson, A Figueroa, R Llanos, M Ackland, A Michalczyk, H Fullriede, G Brennan, J Mercer, M Linder
(2014), Vol. 2, pp. 1-11, Physiological Reports, Oxford, United Kingdom, C1
D Freestone, M Cater, M Ackland, D Paterson, D Howard, M de Jonge, A Michalczyk
(2014), Vol. 25, pp. 377-387, Journal of Nutritional Biochemistry, New York, NY, C1
D Price, M Ackland, W Burks, M Knight, C Suphioglu
(2014), Vol. 33, pp. 1758-1777, Cellular Physiology and Biochemistry, Basel, Switzerland, C1
Glutaredoxin1 protects neuronal cells from copper-induced toxicity
M Cater, S Materia, Z Xiao, K Wolyniec, S Ackland, Y Yap, N Cheung, S La Fontaine
(2014), Vol. 27, pp. 661-672, Biometals, New York, N.Y., C1
Zinc and zinc transporters in macrophages and their roles in efferocytosis in COPD
R Hamon, C Homan, H Tran, V Mukaro, S Lester, E Roscioli, M Bosco, C Murgia, M Ackland, H Jersmann, C Lang, P Zalewski, S Hodge
(2014), Vol. 9, pp. 1-9, PLoS one, San Francisco, CA, C1
Y Song, L Hudek, D Freestone, J Puhui, A Michalczyk, Z Senlin, M Ackland
(2014), Vol. 11, pp. 653-660, Environmental Chemistry, Clayton, Vic., C1
Zinc homeostasis in cyanobacteria
L Hudek, A Michalczyk, B Neilan, M Ackland
(2013), pp. 245-253, Stress biology of cyanobacteria : molecular mechanisms to cellular responses, Boca Raton, Flo., B1-1
X Cao, M Liu, Y Song, M Ackland
(2013), Vol. 185, pp. 2231-2241, Environmental monitoring and assessment, Dordrecht, Netherlands, C1
L Hudek, L Pearson, A Michalczyk, B Neilan, M Ackland
(2013), Vol. 97, pp. 8649-8662, Applied microbiology and biotechnology, Berlin, Germany, C1
Molecular and cellular characterisation of the zinc uptake (Znu) system of Nostoc punctiforme
L Hudek, L Pearson, A Michalczyk, B Neilan, M Ackland
(2013), Vol. 86, pp. 149-171, FEMS microbiology ecology, Oxford, England, C1
hZip1 (hSLC39A1) regulates zinc homoeostasis in gut epithelial cells
A Michalczyk, M Ackland
(2013), Vol. 8, pp. 475-486, Genes and nutrition, Berlin, Germany, C1
C Hogstrand, P Kille, M Ackland, S Hiscox, K Taylor
(2013), Vol. 455, pp. 229-237, Biochemical journal, London, England, C1
Nuts 'n' guts: transport of food allergens across the intestinal epithelium
D Price, L Ackland, C Suphioglu
(2013), Vol. 3, pp. 257-265, Asia Pacific allergy, Seoul, Korea, C1-1
Effects of zinc and DHA on the epigenetic regulation of human neuronal cells
N Sadli, M Ackland, D De Mel, A Sinclair, C Suphioglu
(2012), Vol. 29, pp. 87-98, Cellular physiology and biochemistry, Basel, Switzerland, C1
Copper levels in buccal cells of vineyard workers engaged in various activities
T Thompson, D Freestone, A Michalczyk, M Ackland
(2012), Vol. 56, pp. 305-314, Annals of occupational hygiene, Oxford, England, C1
Y Chu, E Sauble, A Cabrera, A Roth, M Ackland, J Mercer, M Linder
(2012), Vol. 25, pp. 373-382, BioMetals, Dordrecht, The Netherlands, C1
Physiological metal uptake by Nostoc punctiforme
L Hudek, S Rai, A Michalczyk, L Rai, B Neilan, M Ackland
(2012), Vol. 25, pp. 893-903, BioMetals, Dordrecht, The Netherlands, C1
X Yang, Y Song, M Ackland, Y Liu, X Cao
(2012), Vol. 89, pp. 1148-1153, Bulletin of environmental contamination and toxicology, New York, N. Y., C1
H Hugo, S Lebret, E Tomaskovic-Crook, N Ahmed, T Blick, D Newgreen, E Thompson, M Ackland
(2012), Vol. 5, pp. 83-93, Cancer microenvironment, Dordrecht, The Netherlands, C1
N Sadli, N Ahmed, M Ackland, A Sinclair, C Barrow, C Suphioglu
(2011), pp. 141-164, Neurodegenerative diseases - processes, prevention, protection and monitoring, Rijecka, Croatia, B1
P Ji, T Sun, Y Song, M Ackland, Y Liu
(2011), Vol. 159, pp. 762-768, Environmental pollution, Oxford, England, C1
B Hardman, S Luff, M Ackland
(2011), Vol. 32, pp. 79-85, Placenta, Oxford, England, C1
H Hugo, M Kokkinos, T Blick, M Ackland, E Thompson, D Newgreen
(2011), Vol. 193, pp. 23-40, Cells, tissues, organs : in vivo, in vitro, Basel, Switzerland, C1
C Lang, M Hansen, E Roscioli, J Jones, C Murgia, M Ackland, P Zalewski, G Anderson, R Ruffin
(2011), Vol. 24, pp. 23-39, BioMetals, Dordrecht, Netherlands, C1
A Fukunaka, Y Kurokawa, F Teranishi, I Sekler, K Oda, M Ackland, V Faundez, M Hiromura, S Masuda, M Nagao, S Enomoto, T Kambe
(2011), Vol. 286, pp. 16363-16373, Journal of biological chemistry, Bethesda, Md., C1
C Murgia, D Grosser, A Truong-Tran, E Roscioli, A Michalczyk, M Ackland, M Stoltenberg, G Danscher, C Lang, D Knight, G Perozzi, R Ruffin, P Zalewski
(2011), Vol. 3, pp. 910-928, Nutrients, Basel, Switzerland, C1
C Suphioglu, N Sadli, D Coonan, L Kumar, D De Mel, J Lesheim, A Sinclair, L Ackland
(2010), Vol. 103, pp. 344-351, British journal of nutrition, [Cambridge, England], C1
C Suphioglu, D De Mel, L Kumar, N Sadli, D Freestone, A Michalczyk, A Sinclair, M Ackland
(2010), Vol. 584, pp. 612-618, FEBS letters, Amsterdam, The Netherlands, C1
Assessing health risk of reclaimed water using human cell culture.
M Ackland, A Michalczyk, D Freestone, F Stagnitti
(2010), Vol. 37, pp. 39-43, Water, St Leonards, N.S.W., C1
Mammalian copper-transporting P-type ATPases, ATP7A and ATP7B : emerging roles
S La Fontaine, M Ackland, J Mercer
(2010), Vol. 42, pp. 206-209, International journal of biochemistry & cell biology, Oxford, England, C1
Nutritional and functional status indicators in residents of a long-term care facility
J Grieger, C Nowson, L Ackland
(2009), Vol. 28, pp. 47-60, Journal of nutrition for the elderly, New York, N.Y., C1
Multivitamin supplementation improves nutritional status and bone quality in aged care residents
J Grieger, C Nowson, H Jarman, R Malon, L Ackland
(2009), Vol. 63, pp. 558-565, European journal of clinical nutrition, Basingstoke, England, C1
M Colomiere, A Ward, C Riley, M Trenerry, D Cameron-Smith, J Findlay, L Ackland, N Ahmed
(2009), Vol. 100, pp. 134-144, British journal of cancer, London, England, C1
M Colomiere, J Findlay, L Ackland, N Ahmed
(2009), Vol. 41, pp. 1034-1045, The international journal of biochemistry and cell biology, Oxford, England, C1
Bioinformatic and expression analyses of genes mediating zinc homeostasis in Nostoc punctiforme
L Hudek, L Rai, D Freestone, A Michalczyk, M Gibson, Y Song, M Ackland
(2009), Vol. 75, pp. 784-791, Applied and environmental microbiology, Washington, D.C., C1
Y Song, L Wang, X Li, W Zhang, L Chen, D Freestone, P Ji, M Ackland
(2009), Vol. 29, pp. 381-388, Acta scientiae circumstantiae, Beijing, China, C1
Multicellular spheroids in ovarian cancer metastases: Biology and pathology
K Shield, M Ackland, N Ahmed, G Rice
(2009), Vol. 113, pp. 143-148, Gynecologic oncology, San Diego, Calif., C1
D Ackland, V Yap, M Ackland, J Williams, R de Steiger
(2009), Vol. 17, pp. 296-300, Journal of orthopaedic surgery, Hong Kong, C1-1
Y Song, X Li, W Zhang, D Freestone, M Ackland, L Chen, P Ji, X Yang
(2009), Vol. 29, pp. 3768-3774, Acta ecologica sinica, Beijing, China, C1-1
S Overbeck, P Uciechowski, M Ackland, D Ford, L Rink
(2008), Vol. 83, pp. 368-380, Journal of leukocyte biology, Bethesda, Md., C1
ATP7B expression in human breast epithelial cells is mediated by lactational hormones
A Michalczyk, E Bastow, M Greenough, J Camakaris, D Freestone, P Taylor, M Linder, J Mercer, M Ackland
(2008), Vol. 56, pp. 389-399, Journal of histochemistry and cytochemistry, Seattle, Wash., C1
Copper transport during lactation in transgenic mice expressing the human ATP7A protein
R Llanos, A Michalczyk, D Freestone, S Currie, M Linder, M Ackland, J Mercer
(2008), Vol. 372, pp. 613-617, Biochemical and biophysical research communications, San Diego, Calif., C1
Annetocin and TCTP expressions in the earthworm Eisenia fetida exposed to PAHs in artificial soil
S Zheng, Y Song, X Qui, T Sun, M Ackland, W Zhang
(2008), Vol. 71, pp. 566-573, Ecotoxicology and environmental safety, Maryland Heights, Mo., C1
S Zheng, Y Song, X Qiu, T Sun, W Zhang, M Ackland
(2008), Vol. 29, pp. 391-397, Chinese journal of environmental science, Beijing, China, C1
B Hardman, A Michalczyk, M Greenough, J Camakaris, J Mercer, L Ackland
(2007), Vol. 402, pp. 241-250, Biochemical journal, London, England, C1
Epithelial - mesenchymal and mesenchymal - epithelial transitions in carcinoma progression
H Hugo, L Ackland, T Blick, M Lawrence, J Clements, E Williams, E Thompson
(2007), Vol. 213, pp. 374-383, Journal of cellular physiology, New York, N.Y., C1
Y Song, P Gong, B Wilke, W Zhang, X Song, T Sun, L Ackland
(2007), Vol. 9, pp. 182-186, Journal of environmental monitoring, London, England, C1
K Shield, C Riley, M Quinn, G Rice, L Ackland, N Ahmed
(2007), Vol. 6, pp. 1-15, Journal of carcinogenesis, London, England, C1
S Lebret, D Newgreen, E Thompson, L Ackland
(2007), Vol. 9, pp. 1-15, Breast cancer research, London, England, C1
L Ackland, L Zou, D Freestone, S van de Waasenburg, A Michalczyk
(2007), Vol. 85, pp. 617-622, Immunology and cell biology, London, England, C1
J Grieger, C Nowson, L Ackland
(2007), Vol. 16, pp. 178-186, Asia Pacific journal of clinical nutrition, Melbourne, Vic., C1
B Hardman, A Michalczyk, M Greenough, J Camakaris, J Mercer, L Ackland
(2007), Vol. 20, pp. 1073-1084, Cellular physiology and biochemistry, Basel, Switzerland, C1
W Zhang, Y Song, T Sun, M Liu, L Ackland, G Belogolova
(2007), Vol. 18, pp. 2097-2103, Chinese journal of applied ecology, China, C1
B Hardman, U Manuelpillai, E Wallace, J Monty, D Kramer, Y Kuo, J Mercer, L Ackland
(2006), Vol. 27, pp. 968-977, Placenta, London, England, C1
Zinc deficiency and its inherited disorders - A review
L Ackland, A Michalczyk
(2006), Vol. 1, pp. 41-50, Genes & nutrition, New Orleans, LA, C1
Apoptosis may underlie the pathology of zinc-deficient skin
D Wilson, G Varigos, L Ackland
(2006), Vol. 84, pp. 28-37, Immunology and cell biology, Adelaide, S.Aust., C1
S Lebret, D Newgreen, M Waltham, J Price, E Thompson, L Ackland
(2006), Vol. 42, pp. 298-307, In vitro cellular & developmental biology - animal, New York, N. Y., C1
L Ackland, S van de Waasenburg, R Jones
(2005), Vol. 19, pp. 69-76, In Vivo: international journal of experimental and clinical pathophysiology and drug research, Athens, Greece, C1
Perinatal ω-3 polyunsaturated fatty acid supply modifies brain zinc homeostasis during adulthood
A Jayasooriya, L Ackland, M Mathai, A Sinclair, H Weisinger, R Weisinger, J Halver, K Kitajka, L Puskas
(2005), Vol. 102, pp. 7133-7138, Proceedings of the National Academy of Sciences, Washington, D.C., C1
M Ackland, S Van De Waarsenburg, R Jones
(2005), Vol. 19, pp. 69-76, in vivo, Athens, Greece, C1-1
Fresh and cultured buccal cells as a source of mRNA and protein for molecular analysis
A Michalczyk, G Varigos, L Smith, L Ackland
(2004), Vol. 37, pp. 2-7, Biotechniques, Natick, Mass., C1
Expression and localization of Menkes and Wilson copper transporting ATPases in human placenta
B Hardman, U Manuelpillai, E Wallace, S van de Waasenburg, M Cater, J Mercer, L Ackland
(2004), Vol. 25, pp. 512-517, Placenta, Amsterdam, Netherlands, C1
Epidermal growth factor-induced epithelio-mesenchymal transition in human breast carcinoma cells
L Ackland, D Newgreen, M Fridman, M Waltham, A Arvanitis, J Minichiello, J Price, E Thompson
(2003), Vol. 83, pp. 435-448, Laboratory investigation, Baltimore, Md., C1
A Michalczyk, G Varigos, A Catto-Smith, R Blomeley, L Ackland
(2003), Vol. 113, pp. 202-210, Human genetics, Berlin, Germany, C1
L Ackland, J Ward, C Ackland, M Greaves, M Walker
(2003), Vol. 39, pp. 428-433, In vitro cellular and development biology - animal, Raleigh, N.C., C1-1
Constitutive expression of hZnT4 zinc transporter in human breast epithelial cells
A Michalczyk, J Allen, R Blomeley, L Ackland
(2002), Vol. 364, pp. 105-113, Biochemical journal, London, England, C1
PMC42, a novel model for the differentiated human breast
L Ackland, A Michalczyk, R Whitehead
(2001), Vol. 263, pp. 14-22, Experimental cell research, St. Louis, Mo., C1
Creatine transporter protein content, localization, and gene expression in rat skeletal muscle
R Murphy, G McConell, D Cameron-Smith, K Watt, L Ackland, B Walzel, T Wallimann, R Snow
(2001), Vol. 280, American journal of physiology. Cell physiology, Bethesda, Md., C1
Lactation affects expression of intermediate filaments in human breast epithelium
A Michalczyk, R Brown, J Collins, M Ackland
(2001), Vol. 67, pp. 41-49, Differentiation, Amsterdam, The Netherlands, C1-1
A Michalczyk, J Rieger, K Allen, J Mercer, M Ackland
(2000), Vol. 352, pp. 565-571, Biochemical journal, London, Eng., C1-1
Zinc intake and status in Australian vegetarians
M Ball, M Ackland
(2000), Vol. 83, pp. 27-33, British Journal of Nutrition, Cambridge, Eng., C1-1
Metallothionein isoform expression by breast cancer cells
N Barnes, M Ackland, E Cornish
(2000), Vol. 32, pp. 895-903, The International Journal of Biochemistry & Cell Biology, Oxford, Eng., C1-1
M Ackland, P Anikijenko, A Michalczyk, J Mercer
(1999), Vol. 47, pp. 1553-1562, Journal of Histochemistry and Cytochemistry, Thousand Oaks, Calif., C1-1
Expression of Menkes disease gene in mammary carcinoma cells
M Ackland, E Cornish, A Paynter, A Grimes, A Michalczyk, F Mercer
(1997), Vol. 328, pp. 237-243, Biochemical journal, London, Eng., C1-1
Cation-dependent uptake of zinc in human fibroblasts
M Ackland, H McArdle
(1996), Vol. 9, pp. 29-37, Biometals, Dordrecht, Netherlands, C1-1
The effect of tetrathiomolybdate on the metabolism of copper by hepatocytes and fibroblasts.
H McArdle, S Gross, H Vogel, M Ackland, D Danks
(1989), Vol. 22, pp. 179-188, Biological Trace Element Research, United States, C1-1
Funded Projects at Deakin
Australian Competitive Grants
Molecular Eco-toxicology for diagnosis of priority pollutants in soil
EmPr Leigh Ackland, Prof Yufang Song
DEST/ISL Grant - Australian-China Special Fund for Science and Tech Cooperation - Department of Education, Science and Technology - International Science Linkages
- 2010: $7,000
- 2007: $23,000
Enzymatic synthesis, microencapsulation and biological evaluation of a new class of omega-3 derived functional food ingredients
Prof Colin Barrow, Prof Ken Walder, Dr Jaroslav Kralovec, Dr Jacqui Adcock, EmPr Leigh Ackland, Dr Ian Musgrave, Dr Wei Zhang
ARC Linkage - Projects Rnd 1, ARC_DUAPAI ARC_Deakin University Australian Postgraduate Award Industry
- 2013: $14,921
- 2012: $183,043
- 2011: $159,949
- 2010: $153,111
Triggering the dormant capacity of fish to make omega 3 fatty acids
Prof Giovanni Turchini, Prof Andrew Sinclair, EmPr Leigh Ackland
ARC - Discovery Projects
- 2014: $57,969
- 2013: $56,269
- 2012: $86,138
- 2011: $82,946
- 2010: $81,660
The contribution of host caveolin-1 to breast cancer metastasis
A/Prof Robin Anderson, EmPr Leigh Ackland
NHMRC Project Grant
- 2012: $55,000
- 2011: $55,000
- 2010: $55,000
Nanoliposomal delivery of DHA to neuronal cells
EmPr Leigh Ackland, Prof Andrew Sinclair, A/Prof Cenk Suphioglu, Prof Harjinder Singh
ARC - Discovery Projects
- 2014: $99,992
- 2013: $97,059
- 2012: $103,848
NABNEC: A Randomised Phase II Study Of Nab-paclitaxel In Combination With Carboplatin As First Line Treatment Of Gastrointestinal Neuroendocrine Carcinomas
Dr Mustafa Khasraw, A/Prof lara Lipton, Dr Lorraine Chantrill, A/Prof Michael Hofman, EmPr Leigh Ackland, A/Prof Michael Michael, Dr Michael Christie, A/Prof Anthony Gill, Ms Kate Wilson
NHMRC Project Grant
- 2023: $13,572
- 2022: $2,432
- 2021: $8,862
- 2020: $35,366
- 2019: $31,949
- 2018: $14,051
- 2017: $50,656
Multifunctional and environmentally friendly corrosion inhibitor systems
Prof Maria Forsyth, Dr Anthony Somers, EmPr Leigh Ackland, Dr Laura Machuca Suarez, Prof Herman Terryn
ARC - Discovery Projects
- 2020: $151,382
- 2019: $125,975
- 2018: $135,268
Other Public Sector Funding
Orion Conductivity Probes
EmPr Leigh Ackland
NHMRC - Equipment Grant (pre 2017)
- 2014: $670
Metastasis in breast cancer cells
EmPr Leigh Ackland, Miss Vidhula Ahire
DEST Fellowship - Endeavour Research Fellowship - Department of Education, Science and Training
- 2015: $1,500
Whole exome sequencing and methylation profiling of Neuroendocrine cancers from patients on the NABNEC trial
Dr Mustafa Khasraw, Prof David Ashley, EmPr Leigh Ackland
Department of Health and Human Services - Victoria
- 2019: $10,000
- 2018: $60,000
Industry and Other Funding
Enzymatic synthesis, microencapsulation and biological evaluation of a new class of omega-3 derived functional food ingredients
Prof Colin Barrow, Prof Ken Walder, Dr Jaroslav Kralovec, Dr Jacqui Adcock, EmPr Leigh Ackland, Dr Ian Musgrave, Dr Wei Zhang
Ocean Nutrition Canada Ltd
- 2012: $70,607
- 2011: $53,835
- 2010: $52,910
Establishment of a Biosensor Facility at the Centre for Cellular and Molecular Biology (CCMB), Deakin University, Burwood.
A/Prof Cenk Suphioglu, EmPr Leigh Ackland, A/Prof Sharon La Fontaine, Prof Julian Mercer
Clive and Vera Ramaciotti Foundation - Equipment Grant
- 2011: $50,000
Establishment of a Flow Cytometry Facility at the Centre for Cellular and Molecular Biology, Deakin University
A/Prof Cenk Suphioglu, EmPr Leigh Ackland, A/Prof Sharon La Fontaine, Prof Julian Mercer
Clive and Vera Ramaciotti Foundation Grant - Research
- 2010: $30,000
Optimisation of the carotenoid biosynthesis from Haematococcus pluvialis
Dr Angel Torriero, EmPr Leigh Ackland
AquaTrophic Pty Ltd
- 2014: $28,140
Preliminary screening of a saltwater lake sample to identify potentially useful pigment molecules
Dr Angel Torriero, Mr Lee Hudek, EmPr Leigh Ackland
AquaTrophic Pty Ltd
- 2014: $5,000
A Feasibility Study Of NAB-Paclitaxel In Combination With Carboplatin As First Line Treatment Of Gastrointestinal Neuroendocrine Carcinomas (NABNEC)
Dr Mustafa Khasraw, EmPr Leigh Ackland
Specialised Therapeutics Australia Pty. Ltd
- 2015: $12,500
Characterisation of magnetic or other beads modified with proteins
EmPr Leigh Ackland, Dr Angel Torriero
Universal Biosensors Pty Ltd
- 2015: $10,000
Whole exome sequencing and methylation profiling of Neuroendocrine cancers from patients on the NABNEC trial
Dr Mustafa Khasraw, Prof David Ashley, EmPr Leigh Ackland
Grace King Family
- 2020: $21,305
- 2017: $4,570
- 2016: $4,124
Amplification strategies in point-of-care electrochemical biosensors
Dr Angel Torriero, EmPr Leigh Ackland, Dr Ron Chatelier
Universal Biosensors Pty Ltd
- 2019: $40,000
- 2018: $80,000
Targeting site specific improvements of clinical trial operational processes.
EmPr Leigh Ackland, Ms Sharnel Amber Shing Clatworthy
St Vincent's Hospital Melbourne Limited
- 2019: $20,500
Identification of cancer cell markers for early detection
EmPr Leigh Ackland
The Bourne Foundation
- 2021: $100,000
- 2020: $100,000
- 2019: $100,000
Other Funding Sources
Epigenetic markers as indicators of predisposition to diabetes pilot study
EmPr Leigh Ackland
GGT - Greater Green Triangle University Department of Rural Health
- 2014: $8,000
- 2012: $45,000
Supervisions
Abhirami Venugopal
Thesis entitled: Identification and characterisation of novel markers in neuroendocrine tumour cells
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Marije Liem-Weits
Thesis entitled: Tumour microenvironment interations in breast cancer and the role of caveolin-1
Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences
Md Ahsan Ul Bari
Thesis entitled: Effects of Different Forms of Docosahexaenoic Acid Supplementations on Human Neuronal Cells
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
David Freestone
Thesis entitled: Copper Homeostasis in Human Mammary Epithelial Cells
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Lee Hudek
Thesis entitled: Metal Uptake and Efflux Mechanisms in Nostoc Punctiforme
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Lisa Jane McCarthy
Thesis entitled: Assessment of Shark Cartilage Extract from Two Commercially Viable Species
Master of Science (Ecology & Environment), School of Life and Environmental Sciences
Kristy Shield
Thesis entitled: In Vitro Spheroids and Metastatic Epithelial Ovarian Cancer
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Stephanie Chantal Lebret
Thesis entitled: Epithelial-Stromal Interactions in Mammary Lineage Development and Carcinogenesis
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Belinda Mary Hardman
Thesis entitled: Copper Transporters in the Human Placenta
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Agnieszka Michalczyk
Thesis entitled: The Function of Zinc Transporter Genes in Human Cells
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Kiera Rachel Flynn
Thesis entitled: Effects of free fatty acid Docosahexaenoic Acid on supported lipid bilayers
Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences
Shilpi Vajpai
Thesis entitled: Characterisation of chromium interactions with Aspergillus flavus
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Sandeep Karbhari Sure
Thesis entitled: Cyanobacterial Nanowires and Characterisation of Cell-Metalloid/Metal Interactions
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Uttara Shankar
Thesis entitled: Effect of different light regimes on the growth and metabolite productivity in microalgae
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Ashwin Kumar Varamballi Mruthunjaya
Thesis entitled: Amplification strategies in point-of-care electrochemical biosensors
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Sharnel Amber Shing Clatworthy
Thesis entitled: Copper in Prostate Cancer: From Basic Science to Therapeutic Investigation
Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences
Ankita Bedi
Thesis entitled: Bioleaching-an approach for synthesizing functionalized nanoformulations for agricultural use
Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences
Nayyar Ahmed
Thesis entitled: Identification and Characterisation of a Novel Interleukin-4 Receptor Antagonist for Allergy Treatment
Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences
Patricia Anne Corbett
Thesis entitled: Histopathological Fish Health Index: a Biomarker of Pollution Effect
Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences
Loveleen Kumar
Thesis entitled: Function of zinc transporters in human cells
Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences
Dwan Price
Thesis entitled: Molecular and immunological analysis of food allergens
Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences
Bianca Jade Sfiligoj
Thesis entitled: Sensitivity of Antarctic marine invertebrates and microalgae to metal exposure
Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences
Nadia Sadli
Thesis entitled: Zinc and docosahexaenoic acid metabolism in brain cells
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Sara Wilkinson
Thesis entitled: The Relationship between Building Adaptation and Property Attributes
Doctor of Philosophy (Architecture and Built Environment), School of Life and Environmental Sciences
Jane Alisa Allardyce
Thesis entitled: Defence Mechanisms of a Resistant Monocot Model to Phytophthora Cinnamomi
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Tiffany Gunning
Thesis entitled: Profiling Secondary Metabolites of Plant Roots Inoculated with Phytophthora cinnamomi
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Dian Wirawan Tjondronegoro
Thesis entitled: Content-based Video Indexing for Sports Applications using Integrated Multi-Modal Approac
Doctor of Philosophy (Information Technology), School of Information Technology