Biography
I am an integrative physiologist with expertise in biomedicine. My recent work includes basic cardiovascular and renal physiology research examining endogenous hydrogen sulfide signalling in cells. I also have a strong track record in tertiary education and public health research.
Read more on Len's profileBiography summary
Physiologist and Medical Educator
Research interests
The role of hydrogen sulfide in vascular and renal physiology
Vertebrate evolution
Statistical modelling of public health data
Affiliations
Editorial Board of American Journal of Physiology - RIC
Teaching interests
Human Physiology
Gastrointestinal Physiology
Renal Physiology
Medicine
Units taught
SLE211 Principles of Physiology
SLE314 Research Placement
HME102 Medicine 1B Renal and Gastrointestinal Physiology
MD pre-clinical
Knowledge areas
Cardiovascular Physiology
Metabolic Physiology
Cell Signalling
Public health
Medicine
Conferences
1. Forgan, L.G., DeLeon, E, Gao, Y, Whiteman, M and Olson, KR. (2017) Hydrogen sulfide and polysulfides mimic the effects of hypoxia in bovine pulmonary and porcine coronary arteries. EB Chicago, USA, A.1012.8
2. Forgan, L.G., McNeill B.A, DeLeon E, Gao, Y and Olson, KR. (2017). Effects of hypoxia on hydrogen sulfide production and degradation gene expression pathways. EB Chicago, USA, A700.9
3. Forgan L.G., Kelly R, McRae N, McDonald P, McNeill B, McCulloch D and N. Stupka (2016). Inhibition of the extracellular matrix protease ADAMTS5 improves strength in fast twitch hindlimb muscles from young, dystrophic mdx mice. AuPS A.138P.
4. McRae N, Forgan L.G., Addinsall, A, McCulloch D and N. Stupka (2016). Consequences of the genetic reduction of the extracellular protein versican on hinlimb muscle function and structure depend on muscle fibre type and age in dystrophic mdx mice. AuPS A.6P.
5. McNeill, B.A., Marshall, R.E., Wong, N.H., Cole, E.V., Stupka, S. and Forgan, L.G. (2016). A disintegrin and metalloproteinase with thrombospondin Motifs (ADAMTS) -1, -15 expression is upregulated in the murine placenta following high fat feeding. Endocrine Society of Australia, Gold Coast, Australia.
6. Forgan, L.G. McNeill, B.A, Donald, J.A. and Stupka, N. (2016). The role of nitric oxide in skeletal muscle contractility during isometric contraction. GAGE, Canberra, Australia.
7. McRae N, Forgan LG, Addinsall, A, Van Der Poel C, McNeill B, McCulloch, D and Stupka N (2015). Genetic reduction of the ECM protein versican modulates the pathology and function of dystrophic mdx mouse hindlimb muscles. AuPS A.7P.
8. McCulloch D, McRae N, Kelly R, Forgan LG, Stupka N (2014). Genetic reduction of an extracellular matrix gene improves contractile function in dystrophic mdx mice. AuPS A.83P.
9. McRae N, Forgan LG, Addinsall A, Van Der Poel, C McCulloch D, Kelly R, Stupka N (2014). Glucocorticoid treatment regulates versican pericellular matrix remodelling during myoblast fusion: implications for muscular dystrophy therapies. AuPS A.119P.
10. Forgan, L.G., McNeill B.A, Edwards S.L., Donald, J.A. (2014) Constitutive nitric oxide synthase gene and protein expression in the green anole lizard (Anolis carolinensis). SEB, San Diego, USA, pp. 86, A.11.26.
11. Tuckey NP, Forgan, L.G., Cook, D and Jerrett, AR. (2014). The cardiorespiratory physiology of spiny rock lobster (Jasus edwardsii) during rest, recovery, and emersion. NZ Marine Sciences Annual Conference in August 2014 in Nelson, NZ. A.41.
12. Forgan, L.G., Cameron, M.S., Lui, Z., Glover, C.N., Takei Y. and Donald, J.A. (2013). Evolution of cGMP second messenger signalling systems in vertebrates. SEB, Valencia, Spain, pp. 86, A.11.26.
13. Donald, J.A., Trajanovska, S., Becker, R., Cameron, M.S. and Forgan, L.G. (2011). The evolution of vascular NO signalling in vertebrates. ANZSCPB Hobart, Australia. A.28.
14. Forgan, L.G. (2011). Cardiorespiratory physiology of spiny rock lobster (Jasus edwardsii) in response to changes in ambient temperature and gas concentration. SEB, Glasgow, Scotland, pp. 89-89, A6.2.
15. Forgan, L. G. (2010). Oxygen dependence of metabolic rate in the muscles of craniates. ANZSCPB Canberra, Australia. A.40.
16. Forgan, L. G. (2008). Oxygen dependent and independent metabolic rates in fish muscles. SEB Marseille, France. pp120. A.6.20.
17. Olson, K. R., Forgan, L.G., Dombkowski, R. A. and Forster, M. E. (2008) Oxygen dependency of hydrogen sulfide-mediated vasoconstriction in cyclostome aortas. EB 22, 1174.5.
18. Forgan, L. G. (2007). Oxygen dependence of hydrogen sulfide-mediated vasoconstriction in the hagfish dorsal aorta. ANZSCPB Perth, Australia. A.15.
19. Forgan, L. G. (2005). The gastrointestinal physiology of Chinook salmon, Onchorynchus tshawytscha affected by GDAS. ANZSCPB Dunedin, New Zealand. A.24.
Professional activities
Journal reviewer for: (1) American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, (2) The Journal of Comparative Physiology B, (3) The Journal of Experimental Biology, (4) General and Comparative Endocrinology, (5) the Journal of Fish Biology and (6) The Journal of Fish Diseases.
Publications
A Addinsall, L Forgan, N McRae, R Kelly, P McDonald, B McNeil, D McCulloch, N Stupka
(2020), Vol. 10, Biomolecules, Switzerland, C1
Vasoactivity of nitrite in the iliac artery of the toad, Rhinella marina
L Forgan, M Sofele, B McNeill, M Cameron, J Donald
(2018), Vol. 314, pp. R242-R251, American journal of physiology regulatory, integrative and comparative physiology, Bethesda, Md., C1
Alex Addinsall, Craig Wright, Chris Shaw, Natasha McRae, Leonard Forgan, Chia-Heng Weng, Xavier Conlan, Paul Francis, Zoe Smith, Sofianos Andrikopoulos, Nicole Stupka
(2018), Vol. 315, pp. R380-R396, American journal of physiology-regulatory, integrative and comparative physiology, Bethesda, Md., C1
Alexandrea Kranz, Leonard Forgan, Gemma Cole, John Endler
(2018), Vol. 72, pp. 1656-1676, Evolution, London, Eng., C1
N McRae, L Forgan, B McNeill, A Addinsall, D McCulloch, C Van Der Poel, N Stupka
(2017), Vol. 18, International Journal of Molecular Sciences, Switzerland, C1
Characterisation and vascular expression of nitric oxide synthase 3 in amphibians
M Cameron, S Trajanovska, L Forgan, J Donald
(2016), Vol. 366, pp. 679-692, Cell and Tissue Research, Germany, C1
The evolution of nitric oxide signalling in vertebrate blood vessels
J Donald, L Forgan, M Cameron
(2015), Vol. 185, pp. 153-171, Journal of comparative physiology B, Berlin, Germany, C1
L Forgan, N Tuckey, D Cook, A Jerrett
(2014), Vol. 184, pp. 437-447, Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, Germany, C1-1
N Tuckey, L Forgan, A Jerrett
(2012), Vol. 356-357, pp. 256-263, Aquaculture, Amsterdam, The Netherlands, C1-1
N Tuckey, L Forgan
(2012), Vol. 133, pp. 1664-1670, Food chemistry, Amsterdam, The Netherlands, C1-1
Oxygen dependence of metabolism and cellular adaptation in vertebrate muscles: a review
L Forgan, M Forster
(2012), Vol. 182, pp. 177-188, Journal of comparative physiology B : biochemical, systemic, and environmental physiology, Berlin, Germany, C1-1
L Forgan, M Forster
(2010), Vol. 151, pp. 57-65, Comparative biochemistry and physiology part C, Philadelphia, Pa., C1-1
L Forgan, A Jerrett, N Tuckey, M Forster
(2010), Vol. 499, pp. 133-143, Thermochimica acta, Amsterdam, The Netherlands, C1-1
Oxygen-dependence of metabolic rate in the muscles of craniates
L Forgan, M Forster
(2010), Vol. 180, pp. 715-729, Journal of comparative physiology B : biochemical, systemic, and environmental physiology, Berlin, Germany, C1-1
Oxygen consumption and blood flow distribution in perfused skeletal muscle of chinook salmon
L Forgan, M Forster
(2009), Vol. 179, pp. 359-368, Journal of comparative physiology B : biochemical, systemic, and environmental physiology, Berlin, Germany, C1-1
Oxygen dependency of hydrogen sulfide-mediated vasoconstriction in cyclostome aortas
K Olson, L Forgan, R Dombkowski, M Forster
(2008), Vol. 211, pp. 2205-2213, Journal of experimental biology, Oxford, United Kingdom, C1-1
L Forgan, M Forster
(2007), Vol. 146, pp. 343-347, Comparative biochemistry and physiology part C, Philadelphia, Pa., C1-1
L Forgan, M Forster
(2007), Vol. 30, pp. 459-469, Journal of fish diseases, Oxford, England, C1-1
Funded Projects at Deakin
No Funded Projects at Deakin found
Supervisions
No completed student supervisions to report