Dr Rupinder Kanwar

STAFF PROFILE

Position

Senior Research Fellow

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Contact

Biography summary

Qualifications
• Ph. D. (Medical Microbiology and Immunology), - Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
• M. Sc. (Medical Microbiology)-Punjab Agricultural University, India.
• B.Sc. (Medical) Punjab University, India.

Research Profile

Dr Rupinder K Kanwar has expertise in the field of biomedicine, especially interdisciplinary work on targeting cancer and chronic inflammation. After her PhD, Dr Kanwar’s multiaward winning research career has focussed on studying the molecular mechanisms and devising treatments for human chronic inflammatory diseases such as atherosclerosis, asthma, multiple sclerosis, bacterial diahhrea / gut health and cancer (colon, breast, liver, prostate, melanoma, retinoblastoma and brain) by employing both in vivo and in vitro models.

She has worked- in India, New Zealand and Australia, in a variety of positions (from postdoctoral to senior scientist positions), supporting and building new research programs related to interdisciplinary research, international collaborations and initiatives in the fields ranging from biomedicine to nanomedicine. She has 17 years’ experience in drug discovery targeting cancer and chronic inflammation, and delivered both academic and industry-oriented research outcomes.

Dr Kanwar’s current research interests focus on targeting molecular pathogenesis of cancer, cardiotoxicity and chronic inflammation, through drug discovery and pharmacogenomics leading to nanodrug and nanodiagnostic developments.

Her team’s research focus is Bench ↔Bedside biomedical research and innovative nanomedicine (emerging area in the future medicine), by employing established and patient derived biological specimens as well as cutting edge techniques of molecular biology, cell biology, immunology, nanobiotechnology, and protein chemistry.

Summary of HDR supervision at Deakin (since 2008)

As a Principal supervisor = 12 HDR students (10 PhD (includes 3 DIRI) + 2 MSc by Research),
Completions PhD =7, MSc= 1
As an Associate supervisor and co-supervisor = 21 HDR students (including 7 DIRI students, I TERI student)

Honours Supervision Completions/ Graduations
• Bachelors of Honours degree completion as a Principal-supervisor =1
• Bachelors of Honours degree completion as a Co-supervisor = 8

Masters of Biotechnology (Honours) project completions (as an associate supervisor) =4

Memberships of Professional Societies/Industry and Government Consortium

• 2016: British Society for Nanomedicine
• 2011-Present: Australian Nanotechnology Network (group membership)
• 2010- Present: Life membership of The Indian Academy of Tropical Parasitology, India.
• 2010- Present: Life membership of Indian Association of Medical Microbiology, India.
• 2010-2012: Membership of Inflammation Research Association (IRA) USA.
• 2010: Membership of Australasian Society for Immunology, Australia. 
• 2002-2006: Immune Team Membership of LactoPharma Consortium, New Zealand. LactoPharma was an exciting milk bioactives discovery joint venture between Fonterra Co-operative Group Limited, New Zealand and Auckland UniServices Limited. It was supported by the investment from New Zealand's Foundation for Research Science and Technology (FRST) and Fonterra NZ.
• 1994-Present: Life membership of Indian Society for Veterinary Immunology and Biotechnology, India.

Research interests

Dr RK Kanwar has expertise in applying cutting edge techniques of immunology, cell biology, molecular biology to study the pathophysiology and therapeutic targets of human cancer and chronic inflammatory diseases (atherosclerosis, asthma and multiple sclerosis) in both in vivo and in vitro models. Dr Kanwar also has skills in delivering industry oriented research and is a key inventor  on number of recent patent applications on devising treatments for chronic inflammatory diseases. Her current research focus is on combining nanomedicinal approaches with basic cell biology and immunology research, to devise diagnostics and therapeutics for cancer drug resistance, stemcells,  and chronic inflammatory disease (atherosclerosis and osteoarthritis).

Teaching interests

Cell and tissue engineering, Nanomedicine, Molecular pathogenesis oif disease,

Units taught

2015-2016: HMM305 Cell and Tissue Engineering (Unit Chair & lecturer)
2013-2016: HMO303 Health and Vision Sciences 2 (Guest Lecturer)
2013: HBS 400 Med Innovation (Unit chair)
2013: Bachelor of Medicine Bachelor of Surgery (BMBS) Year 1
(Guest Lecturer Cardio-respiratory Physiology)
2013: HMH 401 Developing Research Skills (Assessment Panel Member)
2012: SEK302 Nanomedicine (Assessment Panel Member)
2009-2011: SBB320 Nanobiotechnology (Unit Co-Chair, Lecturer, Assessment Panel Member)
2008-2009: SEK302 Nanomedicine (Unit Co-Chair and Guest Lecturer)
2008: SBB320 Nanobiotechnology (Unit Co-Chair, Assessment Panel Member and Guest Lecturer)
2008: SBB706 Frontier Techniques in Biotechnology and Nanotechnology (Guest Lecturer)
2006-2007: SBB323 Immunology (Lecturer).
2007: SBB234 Microbiology (Guest Lecturer).

Problem Based Learning (PBL) facilitator for Bachelor Medicine Bachelor of Surgery,

• Brain and Behaviour (2016)
• Infection Defence Repair (2015),
• Cardio-respiratory Physiology (2014)


Teaching at the University of Auckland, New Zealand
2006: MEDSCI 708 Advanced Immunology and Immunotherapy.
2002-2005: Molecular Medicine 712 (Advanced Immunology).
2000-2001: Integrin Signalling in Molecular Medicine 545.70

Professional activities

• Editorial board member, Future Science OA (UK)
• Editorial advisory board member Recent Patents on Anti-Infective Drug Discovery
• Manuscript reviewer for ten peer reviewed journals including PloS One, Journal Pharmacology and Experimental Therapeutics [American Society for Pharmacology and Experimental Therapeutics (ASPET), Current Medicinal Chemistry, Journal of Nanomaterials; Evidence-based Complementary and Alternative Medicine (eCAM) 
• Conference organising committee member and Moderator: 5th Asia-Pacific Summit on Cancer 2015, Brisbane, Australia.
• Scientific organizing committee member & symposium Co- chair 17th, Inflammation Research Association conference in USA, 2012.
• Poster judging panel member for 17th, Inflammation Research Association conference in USA, 2012.
• Grant application assessor for NHMRC; and Research Grant Council (RGC) of Hong Kong. 2010.
• Invited speaker and session chair/co-chair at national & international conferences since 2009.
• 2003-2006: Member of the Animal Resource Unit (ARU) Management committee of the University of Auckland, New Zealand (2003-March 2006)
At Deakin
• 2012-present: HDR Candidature confirmation panel member for BioDeakin, ITRI/IFM and School of Medicine.
• 2008-2011: HDR co-ordinator for BioDeakin in ITRI and IFM.

Awards

2015: Vice-Chancellor’s Award for Excellence in Research Supervision (Highly Commended).

2013: Vice Chancellor’s Award for Outstanding Contribution to Deakin Connectedness

2011. Selection for Deakin “Academic Women Aspiring to Leadership (AWAL)” Program.

2010: Charles River Competition “The Most Therapeutic Potential category award” at 16th International Inflammation Research Association Conference, Washington Dulles, Chantilly, Virginia. USA, (September 26-29). (The abstract # 112 was also selected for symposium’s invited presentation).


2005: Travel award Department of Molecular Medicine & Pathology, Faculty of Medicine and Health Science, The University of Auckland, New Zealand.

2004: Poster presentation award at the Conference of the International Society for Cancer Gene Therapy, Singapore. Work was also selected for an oral presentation (21 & 22 February 2004).

2003: Travel grant award Department of Molecular Medicine & Pathology, Faculty of Medicine and Health Science, University of Auckland New Zealand.

2003: Travel grant award Maurice and Phyllis Paykel Trust, New Zealand.

1995- 1996: Research Associateship* Department of Veterinary Immunology, College of Veterinary Sciences, Punjab Agricultural University (PAU), Ludhiana, India.

1993-1994: Senior Research Fellowship* Department of Veterinary Immunology, College of Veterinary Sciences, Punjab Agricultural University (PAU), Ludhiana, India.

March 1993 –Nov 1993: Senior Research Fellowship* Department of Experimental Medicine & Biotechnology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

August 1992-Feb 1992: PGIMER, Directors’ Fellowship award, India.

Jan1989 - July 1992: Junior Research Fellowship, Indian Council of Medical Research Postgraduate fellowship award, Department of Experimental Medicine & Biotechnology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

*These were All India Merit Early Career Research Fellowship awards from CSIR, India equivalent to DECRA (ARC) and NHMRC career development awards such as Peter Doherty in Australia.

1985: B.Sc. Medical  Merit list 25th rank (in Top 1% of total candidates in Punjab state, India) in the Punjab University, India.

1984: Class Topper Award for B.Sc.Year II in Khalsa College for Women, India.

1982-1983: Merit Scholarship Award of Punjab University Chandigarh, India, (BSc Medical).

1981-1982: Khalsa Diwan Merit Scholarship for B.Sc. Medical Year I.


 

Publications

Filter by

2016

Biodegradable Eri silk nanoparticles as a delivery vehicle for bovine lactoferrin against MDA-MB-231 and MCF-7 breast cancer cells

Dr Kislay Roy, Mr Yogesh Patel, Dr Rupinder Kanwar, Dr Rangam Rajkhowa, Prof Xungai Wang, Prof Jagat Kanwar

(2016), Vol. 11, pp. 25-44, International journal of nanomedicine, Macclesfield, Eng., C1

journal

Comparative activities of milk components in reversing chronic colitis.

Prof Jagat Kanwar, Dr Rupinder Kanwar, S Stathopoulos, Neill Haggarty, Alister MacGibbon, Kate P. Palmano, Dr Kislay Roy, Angela Rowan, Geoffrey W Krissansen

(2016), Vol. 99, pp. 2488-2501, Journal of dairy science, Amsterdam, The Netherlands, C1

journal

Probing the biophysical interaction between Neocarzinostatin toxin and EpCAM RNA aptamer

Mr Prasanna Kumar Athyala, Prof Jagat Kanwar, Mohamed Alameen, Dr Rupinder Kanwar, Dr Subramanian Krishnakumar, Prof Jon Watson, Umashankar Vetrivel, Dr Narayanan Janakiraman

(2016), Vol. 469, pp. 257-262, Biochemical and biophysical research communications, Amsterdam, The Netherlands, C1

journal
2015

Fe-bLf nanoformulation targets survivin to kill colon cancer stem cells and maintains absorption of iron, calcium and zinc

Prof Jagat Kanwar, Mr VNL Ganesh Mahidhara, Dr Kislay Roy, Sreenivasan Sasidharan, Dr Krishnakumar Subramanian, Neerati Prasad, Prof Rakesh Sehgal, Dr Rupinder Kanwar

(2015), Vol. 10, pp. 35-55, Nanomedicine, London, United Kingdom, C1

journal

Lactoferrin induced neuronal differentiation: A boon for brain tumours.

Dr Bhasker Sriramoju, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2015), Vol. 41, pp. 28-36, International Journal of Developmental Neuroscience, England, C1

journal

Cissus quadrangularis inhibits IL-1β induced inflammatory responses on chondrocytes and alleviates bone deterioration in osteotomized rats via p38 MAPK signaling

Prof Jagat Kanwar, Dr Rasika Samarasinghe, Prof Kuldeep Kumar, Ramesh Arya, Sanjeev Sharma, Shu-Feng Zhou, Sreenivasan Sasidharan, Dr Rupinder Kanwar

(2015), Vol. 9, pp. 2927-2940, Drug Design, Development and Therapy, Auckland, N.Z., C1

journal

Nanoformulated mutant SurR9-C84A: a possible key for alzheimer's and its associated inflammation

Dr Bhasker Sriramoju, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2015), Vol. 32, pp. 2787-2797, Pharmaceutical research, New York, N. Y., C1

journal

Upregulation of sodium iodide symporter (NIS) protein expression by an innate immunity component: promising potential for targeting radiosensitive retinoblastoma

Miss Jaisy Samuel, Mr Narinderbir Singh, Prof Jagat Kanwar, Subramanium Krishnakumar, Dr Rupinder Kanwar

(2015), Vol. 139, pp. 108-114, Experimental eye research, Amsterdam, The Netherlands, C1

journal

Brain targeted PLGA nanocarriers alleviating amyloid-Β expression and preserving basal survivin in degenerating mice model

Dr Bhasker Sriramoju, Neerati Prasad, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2015), Vol. 1852, pp. 2423-2431, Biochimica et biophysica acta, Amsterdam, The Netherlands, C1

journal

LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging

Dr Kislay Roy, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2015), Vol. 71, pp. 84-99, Biomaterials, Amsterdam, The Netherlands, C1

journal

Iron-free and iron-saturated bovine lactoferrin inhibit survivin expression and differentially modulate apoptosis in breast cancer

Miss Jessica Gibbons, Prof Jagat Kanwar, Dr Rupinder Kanwar

(2015), Vol. 15, pp. 1-16, BMC cancer, London, Eng., C1

journal

Chimeric nucleolin aptamer with survivin DNAzyme for cancer cell targeted delivery

Ms Nithya Subramanian, Prof Jagat Kanwar, Balachandran Akilandeswari, Dr Rupinder Kanwar, Vikas Khetan, Dr Subramanian Krishnakumar

(2015), Vol. 51, pp. 6940-6943, Chemical communications, Cambridge, Eng., C1

journal

Oral administration of iron-saturated bovine lactoferrin-loaded ceramic nanocapsules for breast cancer therapy and influence on iron and calcium metabolism

Ganesh Mahidhara, Dr Rupinder Kanwar, Dr Kislay Roy, Prof Jagat Kanwar

(2015), Vol. 10, pp. 4081-4098, International journal of nanomedicine, Auckland, N. Z., C1

journal

EpCAM Aptamer-siRNA chimera targets and regress epithelial cancer

Ms Nithya Subramanian, Prof Jagat Kanwar, Dr Rupinder Kanwar, JagadeeshBabu Sreemanthula, Jyotirmay Biswas, Vikas Khetan, Dr Subramanian Krishnakumar

(2015), Vol. 10, pp. 1-19, PLoS one, San Francisco, Calif., C1

journal

Effect of lactoferrin protein on red blood cells and macrophages: mechanism of parasite-host interaction

Namrata Anand, Dr Rupinder Kanwar, Mohan Dubey, R.K. Vahishta, Prof Rakesh Sehgal, Anita K. Verma, Prof Jagat Kanwar

(2015), Vol. 9, pp. 3821-3835, Drug design develeopment and therapy, Auckland, N.Z, C1

journal

Competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model

Dr Kislay Roy, Dr Rupinder Kanwar, Dr Subramanian Krishnakumar, Chun Hei Antonio Cheung, Prof Jagat Kanwar

(2015), Vol. 10, pp. 1019-1043, International journal of nanomedicine, Auckland, N. Z., C1

journal

Blocking the maturation of OncomiRNAs using pri-miRNA-17∼92 aptamer in retinoblastoma

Ms Nithya Subramanian, Prof Jagat Kanwar, Dr Rupinder Kanwar, Dr Subramanian Krishnakumar

(2015), Vol. 25, pp. 47-52, Nucleic acid therapeutics, New Rochelle, N. Y., C1

journal

Locked nucleic acid modified bi-specific aptamer-targeted nanoparticles carrying survivin antagonist towards effective colon cancer therapy

Dr Kislay Roy, Dr Rupinder Kanwar, Chun Hei Antonio Cheung, Miss Cassandra Fleming, Rakesh N Veedu

(2015), Vol. 5, pp. 29008-29016, RSC advances, Cambridge, Eng., C1

journal

Molecular targets in arthritis and recent trends in nanotherapy

Dr Kislay Roy, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2015), Vol. 10, pp. 5407-5420, International journal of nanomedicine, Auckland, N. Z., C1

journal

Quick chip assay using locked nucleic acid modified epithelial cell adhesion molecule and nucleolin aptamers for the capture of circulating tumor cells

Nihal Maremanda, Dr Kislay Roy, Dr Rupinder Kanwar, Vidyarani Shyamsundar, Vijayalakshmi Ramshankar, Arvind Krishnamurthy, Dr Subramanian Krishnakumar, Prof Jagat Kanwar

(2015), Vol. 9, pp. 1-20, Biomicrofluidics, Maryland, United States, C1

journal

Aptamer-targeted oligonucleotide theranostics: a smarter approach for brain delivery and the treatment of neurological diseases

Dr Bhasker Sriramoju, Dr Rupinder Kanwar, Rakesh N Veedu, Prof Jagat Kanwar

(2015), Vol. 15, pp. 1115-1124, Current topics in medicinal chemistry, Bussum, The Netherlands, C1

journal

Nucleic acid-based aptamers: applications, development and clinical trials

Prof Jagat Kanwar, Dr Kislay Roy, Nihal Maremanda, Dr Krishnakumar Subramanian, Rakesh N Veedu, Raj Bawa, Dr Rupinder Kanwar

(2015), Vol. 22, pp. 2539-2557, Current medicinal chemistry, Bussum, The Netherlands, C1

journal

Evaluation of nanoformulated therapeutics in an ex-vivo bovine corneal irritation model

Dr Bhasker Sriramoju, Dr Kislay Roy, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2015), Vol. 29, pp. 917-925, Toxicology in vitro, Amsterdam, The Netherlands, C1

journal

EpCAM aptamer mediated cancer cell specific delivery of EpCAM siRNA using polymeric nanocomplex

Ms Nithya Subramanian, Prof Jagat Kanwar, Prasanna Athalya, Dr Narayanan Janakiraman, Vikas Khetan, Dr Rupinder Kanwar, Sailaja Eluchuri, Dr Subramanian Krishnakumar

(2015), Vol. 22, pp. 1-10, Journal of biomedical science, London, Eng., C1

journal

Neurobehavioral burden of multiple sclerosis with nanotheranostics

Dr Bhasker Sriramoju, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2015), Vol. 11, pp. 2675-2689, Neuropsychiatric disease and treatment, Auckland, New Zealand, C1

journal

Oral administration of encapsulated bovine lactoferrin protein nanocapsules against intracellular parasite Toxoplasma gondii

Namrata Anand, Prof Rakesh Sehgal, Dr Rupinder Kanwar, Mohan Dubey, Rakesh Kumar Vasishta, Prof Jagat Kanwar

(2015), Vol. 10, pp. 6355-6369, International journal of nanomedicine, Auckland, New Zealand, C1

journal

Targeting cancer cells using LNA-modified aptamer-siRNA chimeras

Ms Nithya Subramanian, Prof Jagat Kanwar, Dr Rupinder Kanwar, Dr Subramanian Krishnakumar

(2015), Vol. 25, pp. 317-322, Nucleic acid therapeutics, New Rochelle, N.Y., C1

journal

Ultra-small algal chitosan ocular nanoparticles with iron-binding milk protein prevents the toxic effects of carbendazim pesticide

Mr Pavan Sunkireddy, Dr Rupinder Kanwar, Jagat Ram, Prof Jagat Kanwar

(2015), Vol. 11, pp. 495-511, Nanomedicine, London England, C1

journal
2014

Current protein-based anti-angiogenic therapeutics

Sanjukta Chakrabarti, Prof Colin Barrow, Dr Rupinder Kanwar, Dr Venkata Ramana, Prof Jagat Kanwar

(2014), Vol. 14, pp. 291-312, Mini-reviews in medicinal chemistry, Bussum, The Netherlands, C1

journal

The effect of oral administration of iron saturated-bovine lactoferrin encapsulated chitosan-nanocarriers on osteoarthritis

Dr Rasika Samarasinghe, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2014), Vol. 35, pp. 7522-7534, Biomaterials, Amsterdam, The Netherlands, C1

journal

Aptamer-based therapeutics of the past, present and future: from the perspective of eye-related diseases

Prof Jagat Kanwar, Mr Jayanth Surya Narayanan Shankara Narayanan, Ms Sneha Gurudevan, Dr Rupinder Kanwar

(2014), Vol. 19, pp. 1309-1321, Drug discovery today, Amsterdam, The Netherlands, C1

journal

Properties of bamboo fibres produced using an environmentally benign method

Ms Tara Afrin, Dr Rupinder Kanwar, Prof Xungai Wang, Dr Takuya Tsuzuki

(2014), Vol. 105, pp. 1293-1299, Journal of the textile institute, Abingdon, England, C1

journal

Nanoformulated cell-penetrating survivin mutant and its dual actions

Dr Bhasker Sriramoju, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2014), Vol. 9, pp. 3279-3298, International journal of nanomedicine, Auckland, New Zealand, C1

journal

Nanomedicine based nanoparticles for neurological disorders

Mr Bhasker Sriramoju, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2014), Vol. 21, pp. 4154-4168, Current medicinal chemistry, Bussum, Netherlands, C1

journal

Nanocapsules loaded with iron-saturated bovine lactoferrin have antimicrobial therapeutic potential and maintain calcium, zinc and iron metabolism

Miss Isha Gupta, Prof Rakesh Sehgal, Dr Rupinder Kanwar, Dr Vasu Punj, Prof Jagat Kanwar

(2014), pp. 1-26, Nanomedicine, London, United Kingdom, C1

journal

Bioceramic nanomaterials in medical applications

Prof Jagat Kanwar, Ganesh Mahidhara, Dr Kislay Roy, Dr Rupinder Kanwar

(2014), pp. 163-175, Bioengineered nanomaterials, Boca Raton, Flo., B1

chapter

Clinical aspects for survivin: a crucial molecule for targeting drug-resistant cancers

Ms Neha Singh, Dr Subramanian Krishnakumar, Dr Rupinder Kanwar, Chun Hei Antonio Cheung, Prof Jagat Kanwar

(2014), Vol. 20, pp. 578-587, Drug discovery today, London, Eng., C1

journal
2013

Survivin signaling in clinical oncology : a multifaceted dragon

Prof Jagat Kanwar, Mr Sishir Kumar Kamalapuram, Dr Rupinder Kanwar

(2013), Vol. 33, pp. 765-789, Medicinal research reviews, London, England, C1

journal

RNAi mediated Tiam1 gene knockdown inhibits invasion of retinoblastoma

Ms Nithya Subramanian, Saranya Navaneethakrishnan, Jyotirmay Biswas, Dr Rupinder Kanwar, Prof Jagat Kanwar, Dr Subramanian Krishnakumar

(2013), Vol. 8, pp. e70422-, PLoS One, San Francisco, CA, C1

journal

Immunomodulatory lactoferrin in the regulation of apoptosis modulatory proteins in cancer

Dr Rupinder Kanwar, Prof Jagat Kanwar

(2013), Vol. 20, pp. 450-458, Protein & peptide letters, Bussum, The Netherlands, C1

journal
2012

A novel nanoplatform for oral delivery of anti-cancer biomacromolecules

Mr VNL Ganesh Mahidhara, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2012), Vol. 9, pp. 942-960, International journal of nanotechnology, Olney, England, C1

journal

Emerging engineered magnetic nanoparticulate probes for molecular MRI of atherosclerosis : how far have we come?

Dr Rupinder Kanwar, Mr Rajneesh Chaudhary, Dr Takuya Tsuzuki, Prof Jagat Kanwar

(2012), Vol. 7, pp. 899-916, Nanomedicine, London, England, C1

journal

The origin of the antibacterial property of bamboo

Ms Tara Afrin, Dr Takuya Tsuzuki, Dr Rupinder Kanwar, Prof Xungai Wang

(2012), Vol. 103, pp. 844-849, Textile institute, Oxon, England, C1

journal

Cell-penetrating properties of the transactivator of transcription and polyarginine (R9) peptides, their conjugative effect on nanoparticles and the prospect of conjugation with arsenic trioxide

Prof Jagat Kanwar, Miss Jessica Gibbons, Anita K. Verma, Dr Rupinder Kanwar

(2012), Vol. 23, pp. 471-482, Anti-cancer drugs, Philadelphia, Pa., C1

journal

Cancer targeted nanoparticles specifically induce apoptosis in cancer cells and spare normal cells

Prof Jagat Kanwar, Dr Rupinder Kanwar, Mr VNL Ganesh Mahidhara, Hei Chun Antonio Cheung

(2012), Vol. 65, pp. 5-14, Australian journal of chemistry, Collingwood, VIC., C1

journal

Nano-lactoferrin in diagnostic, imaging and targeted delivery for cancer and infectious diseases

Prof Jagat Kanwar, Dr Rasika Samarasinghe, Prof Rakesh Sehgal, Dr Rupinder Kanwar

(2012), Vol. 4, pp. 31-42, Journal of cancer science & therapy, Westlake, Calif., C1-1

journal

The role of nanomedicine in cell based therapeutics in cancer and inflammation.

Dr Rasika Samarasinghe, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2012), Vol. 1, pp. 133-144, International journal of molecular and cellular medicine, Babol, Iran, C1-1

journal

Novel alginate-enclosed chitosan–calcium phosphate-loaded iron-saturated bovine lactoferrin nanocarriers for oral delivery in colon cancer therapy

Prof Jagat Kanwar, Ganesh Mahidhara, Dr Rupinder Kanwar

(2012), Vol. 7, pp. 1521-1550, Nanomedicine, London, England, C1

journal

Target-specific delivery of doxorubicin to retinoblastoma using epithelial cell adhesion molecule aptamer

Ms Nithya Subramanian, Vaishnavi Raghunathan, Prof Jagat Kanwar, Dr Rupinder Kanwar, Sailaja V. Elchuri, Vikas Khetan, Dr Subramanian Krishnakumar

(2012), Vol. 18, pp. 2783-2795, Molecular vision, Atlanta, Ga., C1

journal

Nanotechnology based platforms for survivin targeted drug discovery

Dr Rasika Samarasinghe, Miss Jessica Gibbons, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2012), Vol. 7, pp. 1083-1092, Expert opinion on drug discovery, London, England, C1

journal

Neurological disorders and therapeutics targeted to surmount the blood-brain barrier

Prof Jagat Kanwar, Dr Bhasker Sriramoju, Dr Rupinder Kanwar

(2012), Vol. 7, pp. 3259-3278, International journal of nanomedicine, Auckland, New Zealand, C1

journal

Emerging engineered magnetic nanoparticulate probes for targeted MRI of atherosclerotic plaque macrophages

Dr Rupinder Kanwar, Mr Rajneesh Chaudhary, Dr Takuya Tsuzuki, Prof Jagat Kanwar

(2012), Vol. 7, pp. 735-749, Nanomedicine, London, England, C1

journal

TH17 cells in cancer related inflammation

Dr Rupinder Kanwar, Prof Jagat Kanwar

(2012), pp. 43-60, Recent advances in immunology to target cancer, inflammation and infections, Rijeka, Croatia, B1-1

chapter

Immunology of Leishmaniasis and future prospective of vaccines

Prof Rakesh Sehgal, Kapil Goyal, Dr Rupinder Kanwar, Alka Sehgal, Prof Jagat Kanwar

(2012), pp. 479-494, Recent advances in immunology to target cancer, inflammation and infections, Rijeka, Croatia, B1-1

chapter

Milk proteins and human health

Prof Jagat Kanwar, Dr Rupinder Kanwar, Dr Munish Puri

(2012), pp. 1-1, Food biotechnology : principles and practices, New Delhi, India, B1-1

chapter
2011

Nanoparticles in the treatment and diagnosis of neurological disorders : untamed dragon with fire power to heal

Prof Jagat Kanwar, Xueying Sun, Dr Vasu Punj, Dr Bhasker Sriramoju, Prof Rajiv R. Mohan, Shu-Feng Zhou, Ashok Chauhan, Dr Rupinder Kanwar

(2011), Vol. 8, pp. 399-414, Nanomedicine : nanotechnology, biology and medicine, Philadelphia, Pa., C1

journal

Antioxidant enzyme activities of iron-saturated bovine lactoferrin (Fe-bLf) in human gut epithelial cells under oxidative stress

Ms Hannah Burrow, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2011), Vol. 7, pp. 224-230, Medicinal chemistry, Bussum, Netherlands, C1

journal

Survivin mutant protects differentiated dopaminergic SK-N-SH cells against oxidative stress

Ms Sara Baratchi, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2011), Vol. 6, pp. 1-8, PLoS ONE, San Francisco, Ca., C1

journal

Targeting survivin in cancer : the cell-signalling perspective

Prof Jagat Kanwar, Mr Sishir Kumar Kamalapuram, Dr Rupinder Kanwar

(2011), Vol. 16, pp. 485-494, Drug Discovery Today, London, United Kingdom, C1

journal

Antiangiogenic therapy using nanotechnological-based delivery system

Prof Jagat Kanwar, Mr VNL Ganesh Mahidhara, Dr Rupinder Kanwar

(2011), Vol. 16, pp. 188-202, Drug discovery today, London, England, C1

journal

Lactoferrin and cancer in different cancer models

Miss Jessica Gibbons, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2011), Vol. S3, pp. 1080-1088, Frontiers in Bioscience, Albertson, N.Y., C1

journal

Novel survivin mutant protects differentiated SK-N-SH human neuroblastoma cells from activated T-cell neurotoxicity

Ms Sara Baratchi, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2011), Vol. 233, pp. 18-28, Journal of neuroimmunology, Amsterdam, Netherlands, C1

journal

Targeting hepatitis B virus and human papillomavirus induced carcinogenesis : novel patented therapeutics

Dr Rupinder Kanwar, Ms Neha Singh, Ms Sneha Gurudevan, Prof Jagat Kanwar

(2011), Vol. 6, pp. 158-174, Recent patents on anti-infective drug discovery, Bussum, Netherlands, C1

journal

Role of nanomedicine in reversing drug resistance mediated by ATP binding cassette transporters and P-glycoprotein in melanoma

Prof Jagat Kanwar, Ms Neha Singh, Dr Rupinder Kanwar

(2011), Vol. 6, pp. 701-714, Nanomedicine, London, England, C1

journal

The use of cyclodextrins nanoparticles for oral delivery

Prof Jagat Kanwar, B. M. Long, Dr Rupinder Kanwar

(2011), Vol. 18, pp. 2079-2085, Current medicinal chemistry, Hilversum, The Netherlands, C1

journal

Toll like receptors play a role in general immunity, eye infection and inflammation : TLRs for nanodelivery

Prof Jagat Kanwar, Shu-Feng Zhou, Ms Sneha Gurudevan, Prof Colin Barrow, Dr Rupinder Kanwar

(2011), Vol. 2, pp. 1-10, Journal of clinical and cellular immunology, Los Angeles, Calif., C1

journal

Chimeric aptamers in cancer cell-targeted drug delivery

Prof Jagat Kanwar, Dr Kislay Roy, Dr Rupinder Kanwar

(2011), Vol. 46, pp. 459-477, Critical reviews in biochemistry and molecular biology, London, England, C1

journal

Effect of selenium-saturated bovine lactoferrin (Se-bLF) on antioxidant enzyme activities in human gut epithelial cells under oxidative stress

Ms Hannah Burrow, Dr Rupinder Kanwar, Mr VNL Ganesh Mahidhara, Prof Jagat Kanwar

(2011), Vol. 11, pp. 762-771, Anti-cancer agents in medicinal chemistry, Bussum, Netherlands, C1

journal
2010

Recent advances in anti-survivin treatments for cancer

Dr Rupinder Kanwar, Chun Hei Antonio Cheung, J. Y. Chang, Prof Jagat Kanwar

(2010), Vol. 17, pp. 1509-1515, Current medicinal chemistry, Hilversum, The Netherlands, C1

journal

Applications of nanomedicine in antibacterial medical therapeutics and diagnostics

Liam Matthews, Dr Rupinder Kanwar, Shu-Feng Zhou, Dr Vasu Punj, Prof Jagat Kanwar

(2010), Vol. 3, pp. 1-9, Open tropical medicine journal, Amsterdam, The Netherlands, C1-1

journal

Survivin : a target from brain cancer to neurodegenerative disease

Ms Sara Baratchi, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2010), Vol. 45, pp. 535-554, Critical reviews in biochemistry and molecular biology, London, England, C1

journal

Targeting survivin in cancer : patent review

Prof Jagat Kanwar, Mr Sishir Kumar Kamalapuram, Dr Rupinder Kanwar

(2010), Vol. 20, pp. 1723-1737, Expert opinion on therapeutic patents, London, England, C1

journal

MicroRNA in human cancer and chronic inflammatory diseases

Prof Jagat Kanwar, Mr VNL Ganesh Mahidhara, Dr Rupinder Kanwar

(2010), Vol. 2, pp. 1113-1126, Frontiers in bioscience (scholar edition), Albertson, N.Y., C1

journal

Recent advances on the possible neuroprotective activities of Epstein-Barr virus oncogene BARF1 protein in chronic inflammatory disorders of central nervous system

Ms Alicia Wynne, Dr Rupinder Kanwar, Rajiv Khanna, Prof Jagat Kanwar

(2010), Vol. 8, pp. 268-275, Current neuropharmacology, Sharjah, United Arab Emirates, C1

journal

Proliferative and protective effects of SurR9-C84A on differentiated neural cells.

Ms Sara Baratchi, Dr Rupinder Kanwar, Chun Hei Antonio Cheung, Prof Jagat Kanwar

(2010), Vol. 227, pp. 120-132, Journal of neuroimmunology, Amsterdam, Netherlands, C1

journal

Applications of aptamers in nanodelivery systems in cancer, eye and inflammatory diseases

Prof Jagat Kanwar, Prof Rajiv R. Mohan, Dr Rupinder Kanwar, Dr Kislay Roy, Raj Bawa

(2010), Vol. 5, pp. 1435-1445, Nanomedicine, London, England, C1

journal
2009

Gut health immunomodulatory and anti-inflammatory functions of gut enzyme digested high protein micro-nutrient dietary supplement-Enprocal

Prof Jagat Kanwar, Dr Rupinder Kanwar

(2009), Vol. 10, pp. 1-19, BMC immunology, London, England, C1

journal

A microfluidic electroosmotic mixer and the effect of potential and frequency on its mixing efficiency

Prof Abbas Kouzani, Mr Khashayar Khoshmanesh, Prof Saeid Nahavandi, Dr Rupinder Kanwar

(2009), pp. 4618-4622, SMC 2009 : Proceedings of the IEEE International Conference on Systems, Man and Cybernetics, Piscataway, N. J., E1

conference

Promises of nanotechnology for drug delivery to brain in neurodegenerative diseases

Ms Sara Baratchi, Dr Rupinder Kanwar, Dr Vasu Punj, Ashok Chauhan, Hittu Matta, Dr Subramanian Krishnakumar, Xueying Sun, Sanjeeb K. Sahoo

(2009), Vol. 5, pp. 15-25, Current Nanoscience, Bussum, Netherlands, C1

journal

Recent advances in nanoneurology for drug delivery to the brain

Prof Jagat Kanwar, Dr Rupinder Kanwar, Mr VNL Ganesh Mahidhara

(2009), Vol. 5, pp. 441-447, Current nanoscience, Bussum, Netherlands, C1

journal

Recent advances on the roles of NO in cancer and chronic inflammatory disorders

Prof Jagat Kanwar, Dr Rupinder Kanwar, Ms Hannah Burrow, Ms Sara Baratchi

(2009), Vol. 16, pp. 2373-2394, Current medicinal chemistry, Bussum, Netherlands, C1

journal

Ribosome inactivating proteins (RIPs) from momordica charantia for anti viral therapy

Dr Munish Puri, Inderdeep Kaur, Dr Rupinder Kanwar, Rita Gupta, Ashok Chauhan, Prof Jagat Kanwar

(2009), Vol. 9, pp. 1080-1094, Current molecular medicine, Bussum, Netherlands, C1

journal

Recent advances of metal binding protein lactoferrin as an anti-microbial agent

Miss Isha Gupta, Dr Rupinder Kanwar, Prof Jagat Kanwar

(2009), Vol. 5, pp. 226-233, Current bioactive compounds, Bussum, Netherlands, C1

journal

Molecular and biotechnological advances in milk proteins in relation to human health

Prof Jagat Kanwar, Dr Rupinder Kanwar, Dr Vasu Punj, Hittu Matta, Somasundaram M. Morley, Prof Andrew Parratt, Dr Munish Puri

(2009), Vol. 10, pp. 308-338, Current protein and peptide science, Bussum, Netherlands, C1

journal
2008

Bovine milk fat enriched in conjugated linoleic and vaccenic acids attenuates allergic airway disease in mice

Dr Rupinder Kanwar, Alister MacGibbon, Peter Black, Prof Jagat Kanwar, Angela Rowan, Molly Vale, Geoffrey W Krissansen

(2008), Vol. 38, pp. 208-218, Clinical and experimental allergy, Oxford, England, C1

journal

'Iron-saturated' lactoferrin is a potent natural adjuvant for augmenting cancer chemotherapy

Prof Jagat Kanwar, Kate P. Palmano, Xueying Sun, Dr Rupinder Kanwar, Rita Gupta, Neill Haggarty, Angela Rowan, Satyendra Ram, Geoffrey W Krissansen

(2008), Vol. 86, pp. 277-288, Immunology and cell biology, London, England, C1

journal
2006

A pseudosymmetric cell adhesion regulatory domain in the β7 tail of the integrin α4β7 that interacts with focal adhesion kinase and src

Geoffrey W Krissansen, Jaison Singh, Dr Rupinder Kanwar, Yih-Chih Chan, Euphemia Leung, Klaus B Lehnert, Prof Jagat Kanwar, Yi Yang

(2006), Vol. 36, pp. 2203-2214, European journal of immunology, Weinheim, Germany, C1-1

journal
2004

Simultaneous neuroprotection and blockade of inflammation reverses autoimmune encephalomyelitis

Prof Jagat Kanwar, Dr Rupinder Kanwar, Geoffrey W Krissansen

(2004), Vol. 127, pp. 1313-1331, Brain : a journal of neurology, Oxford, England, C1-1

journal
2003

Mucosal vascular addressin cell adhesion molecule-1 is expressed outside the endothelial lineage on fibroblasts and melanoma cells

Euphemia Leung, Dr Rupinder Kanwar, Prof Jagat Kanwar, Geoffrey W Krissansen

(2003), Vol. 81, pp. 320-327, Immunology and cell biology, Basingstoke, England, C1-1

journal

Requirements for ICAM-1 immunogene therapy of lymphoma.

Prof Jagat Kanwar, Randy W. Berg, Yi Yang, Dr Rupinder Kanwar, Lai-Ming Ching, Xueying Sun, Geoffrey W Krissansen

(2003), Vol. 10, pp. 468-476, Cancer gene therapy, London, England, C1-1

journal
2001

Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to the eradication of large tumors and multiple tumor foci

Prof Jagat Kanwar, Dr Rupinder Kanwar, Sushil Pandey, Lai-Ming Ching, Geoffrey W Krissansen

(2001), Vol. 61, pp. 1948-1956, Cancer research, Birmingham, Ala., C1-1

journal

Effects of survivin antagonists of growth of established tumors and B7-1 immunogene therapy

Prof Jagat Kanwar, Wei-Ping Shen, Dr Rupinder Kanwar, Randy W. Berg, Geoffrey W Krissansen

(2001), Vol. 93, pp. 1541-1552, Journal of the National Cancer Institute, Oxford, England, C1-1

journal

Temporal expression of heat shock proteins 60 and 70 at lesion-prone sites during atherogenesis in ApoE-deficient mice

Dr Rupinder Kanwar, Prof Jagat Kanwar, Dongmao wang, Douglas J. Ormrod, Geoffrey W Krissansen

(2001), Vol. 21, pp. 1991-1997, Arteriosclerosis thrombosis and vascular biology, Philadelphia, Pa., C1-1

journal
2000

Prevention of a chronic progressive form of experimental autoimmune encephalomyelitis by an antibody against mucosal addressin cell adhesion molecule-1, given early in the course of disease progression.

Prof Jagat Kanwar, Dr Rupinder Kanwar, Dongmao wang, Geoffrey W Krissansen

(2000), Vol. 78, pp. 641-645, Immunology and cell biology, London, England, C1-1

journal
1994

Purification and partial immunochemical characterization of a low molecular mass, diagnostic Echinococcus granulosus immunogen for sheep hydatidosis

Prof Jagat Kanwar, Dr Rupinder Kanwar

(1994), Vol. 9, pp. 101-107, FEMS immunology & medical microbiology, Oxford, England, C1-1

journal

Impairment of Na+,K+-ATPase activity following enterotoxigenic Campylobacter jejuni infection: changes in Na+, Cl-- and 3-O-methyl-D-glucose transport in vitro, in rat ileum

Dr Rupinder Kanwar, Nirmal K Ganguly, Prof Jagat Kanwar, Lata Kumar, B NS Walia

(1994), Vol. 124, pp. 381-385, FEMS microbiology letters, Oxford, England, C1-1

journal

Significance of detection of immune-complexed 8 kDa hydatid-specific antigen for immunodiagnosis of hydatidosis

Prof Jagat Kanwar, Dr Rupinder Kanwar, A S Grewal, V K Vinayak

(1994), Vol. 9, pp. 231-236, FEMS immunology & medical microbiology, Oxford, England, C1-1

journal
1993

Studies on the pathophysiological mechanism of Campylobacter jejuni-induced fluid secretion in rat ileum

Dr Rupinder Kanwar, Nirmal K Ganguly, Lata Kumar, B NS Walia

(1993), Vol. 111, pp. 327-330, FEMS microbiol letters, Amsterdam, Netherlands, C1-1

journal