A/Prof. Sarah Shigdar

Cytotoxic effects of aptamer-doxorubicin conjugates in an ovarian cancer cell line

J Henri, M Nakhjavani, S McCoombe, S Shigdar

(2023), Vol. 204, pp. 108-117, Biochimie, France, C1

The Diagnostic Potential of RNA Aptamers against the NS1 Protein of Dengue Virus Serotype 2

R Thevendran, S Rogini, G Leighton, A Mutombwera, S Shigdar, T Tang, M Citartan

(2023), Vol. 12, pp. 1-24, Biology, Basel, Switzerland, C1

In vitro selection of aptamers and their applications

M DeRosa, A Lin, P Mallikaratchy, E McConnell, M McKeague, R Patel, S Shigdar

(2023), Vol. 3, Nature Reviews Methods Primers, Berlin, Germany, C1

Unravelling the Glioblastoma Tumour Microenvironment: Can Aptamer Targeted Delivery Become Successful in Treating Brain Cancers?

B Giles, M Nakhjavani, A Wiesa, T Knight, S Shigdar, R Samarasinghe

(2023), Vol. 15, pp. 4376-4376, Cancers, Basel, Switzerland, C1

Isolation and Identification of the High-Affinity DNA Aptamer Target to the Brain-Derived Neurotrophic Factor (BDNF)

Md Chowdhury, Jessica Collins, David Gell, Sharn Perry, Michael Breadmore, Sarah Shigdar, Anna King

(2023), ACS Chemical Neuroscience, Washington, DC., C1

Future of PD-1/PD-L1 axis modulation for the treatment of triple-negative breast cancer

M Nakhjavani, S Shigdar

(2022), Vol. 175, pp. 1-11, Pharmacological Research, Amsterdam, The Netherlands, C1

Profiling cancer cells by cell-selex: Use of aptamers for discovery of actionable biomarkers and therapeutic applications thereof

S Shigdar, L Agnello, M Fedele, S Camorani, L Cerchia

(2022), Vol. 14, pp. 1-20, Pharmaceutics, Basel, Switzerland, C1

Triple-negative breast cancer brain metastasis: An update on druggable targets, current clinical trials, and future treatment options

M Nakhjavani, R Samarasinghe, S Shigdar

(2022), Vol. 27, pp. 1298-1314, Drug Discovery Today, Amsterdam, The Netherlands, C1

Modelling of mass transport and distribution of aptamer in blood-brain barrier for tumour therapy and cancer treatment

Mohsen Sarafraz, Maryam Nakhjavani, Sarah Shigdar, Farid Christo, Bernard Rolfe

(2022), Vol. 173, pp. 121-131, European Journal of Pharmaceutics and Biopharmaceutics, Amsterdam, The Netherlands, C1

Natural Blockers of PD-1/PD-L1 Interaction for the Immunotherapy of Triple-Negative Breast Cancer-Brain Metastasis

M Nakhjavani, S Shigdar

(2022), Vol. 14, Cancers, Switzerland, C1

Novel detection of nasty bugs, prevention is better than cure

M Strom, T Crowley, S Shigdar

(2021), Vol. 22, pp. 1-19, International Journal of Molecular Sciences, Switzerland, C1

Diagnostics and therapeutics in targeting her2 breast cancer: A novel approach

C Vi, G Mandarano, S Shigdar

(2021), Vol. 22, International Journal of Molecular Sciences, Switzerland, C1

Aptamers: Cutting edge of cancer therapies

S Shigdar, B Schrand, P Giangrande, V de Franciscis

(2021), Vol. 29, pp. 2396-2411, Molecular Therapy, Amsterdam, The Netherlands, C1

Bifunctional aptamer-doxorubicin conjugate crosses the blood-brain barrier and selectively delivers Its payload to EpCAM-positive tumor cells

J Macdonald, D Denoyer, J Henri, A Jamieson, I Burvenich, N Pouliot, S Shigdar

(2020), Vol. 30, pp. 117-128, Nucleic acid therapeutics, New Rochelle, N.Y., C1

Antibodies, nanobodies, or aptamers-which is best for deciphering the proteomes of non-model species?

P Dhar, R Samarasinghe, S Shigdar

(2020), Vol. 21, International Journal of Molecular Sciences, Switzerland, C1

Non-invasive delivery of therapeutics into the brain: The potential of aptamers for targeted delivery

B Bukari, R Samarasinghe, J Noibanchong, S Shigdar

(2020), Vol. 8, Biomedicines, Switzerland, C1

Mathematical approaches in estimating aptamer-target binding affinity

Ramesh Thevendran, Tholasi Navien, Xin Meng, Kechun Wen, Qiao Lin, S Shigdar, Thean-Hock Tang, Marimuthu Citartan

(2020), Vol. 600, pp. 1-13, Analytical Biochemistry, Amsterdam, The Netherlands, C1

Strategies to bioengineer aptamer-driven nanovehicles as exceptional molecular tools for targeted therapeutics: a review

Ramesh Thevendran, Sarah Shigdar, Thean-Hock Tang, Marimuthu Citartan

(2020), Vol. 323, pp. 530-548, Journal of controlled release, Amsterdam, The Netherlands, C1

Radiolabelled aptamers for theranostic treatment of cancer

Umair Khalid, Chris Vi, Justin Henri, Joanna Macdonald, Peter Eu, Giovanni Mandarano, Sarah Shigdar

(2019), Vol. 12, Pharmaceuticals, Basel, Switzerland, C1

Anything you can do, i can do better: Can aptamers replace antibodies in clinical diagnostic applications?

M Bauer, M Strom, D Hammond, S Shigdar

(2019), Vol. 24, Molecules, Switzerland, C1

Tailored mesoporous silica nanoparticles for controlled drug delivery: Platform fabrication, targeted delivery, and computational design and analysis

X She, L Chen, Z Yi, C Li, C He, C Feng, T Wang, S Shigdar, W Duan, L Kong

(2018), Vol. 18, pp. 976-989, Mini-Reviews in Medicinal Chemistry, Netherlands, C1

Aptamers as potential therapeutic agents for ovarian cancer

J Henri, J Macdonald, M Strom, W Duan, S Shigdar

(2018), Vol. 145, pp. 34-44, Biochimie, Amsterdam, The Netherlands, C1

EpCAM immunotherapy versus specific targeted delivery of drugs

J Macdonald, J Henri, K Roy, E Hays, M Bauer, R Veedu, N Pouliot, S Shigdar

(2018), Vol. 10, Cancers, Switzerland, C1

Mesoporous silica nanorods toward efficient loading and intracellular delivery of siRNA

L Chen, X She, T Wang, S Shigdar, W Duan, L Kong

(2018), Vol. 20, Journal of Nanoparticle Research, C1

Development of transferrin receptor aptamers as drug delivery vehicles for the treatment of brain metastases

Joanna Macdonald, G Mandarano, Rakesh Veedu, Sarah Shigdar

(2018), Vol. 2, pp. 15-27, Aptamers, Oxford, Eng., C1

Challenges and opportunities for siRNA-based cancer treatment

T Wang, S Shigdar, H Shamaileh, M Gantier, W Yin, D Xiang, L Wang, S Zhou, Y Hou, P Wang, W Zhang, C Pu, W Duan

(2017), Vol. 387, pp. 77-83, Cancer Letters, Ireland, C1

Development of a Bifunctional Aptamer Targeting the Transferrin Receptor and Epithelial Cell Adhesion Molecule (EpCAM) for the Treatment of Brain Cancer Metastases

J Macdonald, J Henri, L Goodman, D Xiang, W Duan, S Shigdar

(2017), Vol. 8, pp. 777-784, ACS Chemical Neuroscience, United States, C1

Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells

H Alshamaileh, T Wang, D Xiang, W Yin, P Tran, R Barrero, P Zhang, Y Li, L Kong, K Liu, S Zhou, Y Hou, S Shigdar, W Duan

(2017), Vol. 7, Scientific Reports, England, C1

Transforming doxorubicin into a cancer stem cell killer via EpCAM aptamer-mediated delivery

D Xiang, S Shigdar, A Bean, M Bruce, W Yang, M Mathesh, T Wang, W Yin, P Tran, H Shamaileh, R Barrero, P Zhang, Y Li, L Kong, K Liu, S Zhou, Y Hou, A He, W Duan

(2017), Vol. 7, pp. 4071-4086, Theranostics, Australia, C1

Aptamers and glioblastoma: Their potential use for imaging and therapeutic applications

E Hays, W Duan, S Shigdar

(2017), Vol. 18, International Journal of Molecular Sciences, Switzerland, C1

Development of cell-specific aptamers: Recent advances and insight into the selection procedures

K Rahimizadeh, H Al Shamaileh, M Fratini, M Chakravarthy, M Stephen, S Shigdar, R Veedu

(2017), Vol. 22, Molecules, Switzerland, C1

The Application of Aptamers for Immunohistochemistry

M Bauer, J Macdonald, J Henri, W Duan, S Shigdar

(2016), Vol. 26, pp. 120-126, Nucleic Acid Therapeutics, United States, C1

Truncation and Mutation of a Transferrin Receptor Aptamer Enhances Binding Affinity

J MacDonald, P Houghton, D Xiang, W Duan, S Shigdar

(2016), Vol. 26, pp. 348-354, Nucleic Acid Therapeutics, United States, C1

Nucleic acid aptamer-guided cancer therapeutics and diagnostics: the next generation of cancer medicine

D Xiang, S Shigdar, G Qiao, T Wang, A Kouzani, S Zhou, L Kong, Y Li, C Pu, W Duan

(2015), Vol. 5, pp. 23-42, Theranostics, Wyoming, N.S.W., C1

Aptamer-mediated cancer gene therapy.

D Xiang, S Shigdar, G Qiao, S Zhou, Y Li, M Wei, L Qiao, H Shamaileh, Y Zhu, C Zheng, C Pu, W Duan

(2015), Vol. 15, pp. 109-119, Current Gene Therapy, Bussum, Netherlands, C1

Fabrication of high specificity hollow mesoporous silica nanoparticles assisted by Eudragit for targeted drug delivery.

X She, L Chen, L Velleman, C Li, H Zhu, C He, T Wang, S Shigdar, W Duan, L Kong

(2015), Vol. 445, pp. 151-160, Journal of Colloid and Interface Science, United States, C1

The control of epidermal growth factor grafted on mesoporous silica nanoparticles for targeted delivery

X She, L Chen, L Velleman, C Li, C He, J Denman, T Wang, S Shigdar, W Duan, L Kong

(2015), Vol. 3, pp. 6094-6104, Journal of materials chemistry B, Cambridge, Eng., C1

Superior performance of aptamer in tumor penetration over antibody : implication of aptamer-based theranostics in solid tumors

D Xiang, C Zheng, S Zhou, S Qiao, P Tran, C Pu, Y Li, L Kong, A Kouzani, J Lin, K Liu, L Li, S Shigdar, W Duan

(2015), Vol. 5, pp. 1083-1097, Theranostics, Sydney, N.S.W., C1

Overcoming acquired drug resistance in colorectal cancer cells by targeted delivery of 5-FU with EGF grafted hollow mesoporous silica nanoparticles

L Chen, X She, T Wang, L He, S Shigdar, W Duan, L Kong

(2015), Vol. 7, pp. 14080-14092, Nanoscale, Cambridge, Eng., C1

Cancer stem cell targeted therapy: progress amid controversies

T Wang, S Shigdar, M Gantier,, Y Hou,, L Wang,, Y Li,, H Shamaileh,, W Yin, S Zhou,, X Zhao,, W Duan

(2015), Vol. 6, pp. 44191-44206, Oncotarget, Albany, N.Y., C1

EpCAM aptamer-mediated survivin silencing sensitized cancer stem cells to doxorubicin in a breast cancer model

T Wang, M Gantier, D Xiang, A Bean, M Bruce, S Zhou, M Khasraw, A Ward, L Wang, M Wei, H AlShamaileh, L Chen, X She, J Lin, L Kong, S Shigdar, W Duan

(2015), Vol. 5, pp. 1456-1472, Theranostics, Wyoming, N.S.W., C1

Ethosomes the best approach for deeper delivery of drugs through transdermal port: from preparation to biomedical applications

Syed Raza, Muhammad Sajid, Usama Jamshaid, Talha Jamshaid, Rabia Aslam, Akhlaq Ahmed, Sarah Shigdar, Muhammad Jamshaid

(2015), Vol. 4, pp. 87-98, Journal of colloid science and biotechnology, Los Angeles, Calif., C1

Improved efficacy and reduced toxicity of doxorubicin encapsulated in sulfatide-containing nanoliposome in a glioma model

J Lin, S Shigdar, D Fang, D Xiang, M Wei, A Danks, L Kong, L Li, L Qiao, W Duan

(2014), Vol. 9, pp. 1-13, Plos One, San Francisco, CA, C1

Cancer stem cells: a contentious hypothesis now moving forward

M O'Connor, D Xiang, S Shigdar, J Macdonald, Y Li, T Wang, C Pu, Z Wang, L Qiao, W Duan

(2014), Vol. 344, pp. 180-187, Cancer letters, Shannon, Ireland, C1

CD44 variant 6 is associated with prostate cancer metastasis and chemo-/radioresistance

J Ni, P Cozzi, J Hao, J Beretov, L Chang, W Duan, S Shigdar, W Delprado, P Graham, J Bucci, J Kearsley, Y Li

(2014), Vol. 74, pp. 602-617, Prostate, Hoboken, NJ, C1

Epithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells

L Li, D Xiang, S Shigdar, W Yang, Q Li, J Lin, K Liu, W Duan

(2014), Vol. 9, pp. 1083-1096, International journal of nanomedicine, Macclesfield, England, C1

RNA aptamers targeting cancer stem cell marker CD133

S Shigdar, L Qiao, S Zhou, D Xiang, T Wang, Y Li, L Lim, L Kong, L Li, W Duan

(2013), Vol. 330, pp. 84-95, Cancer letters, Amsterdam, Netherlands, C1

The use of sensitive chemical antibodies for diagnosis: detection of low levels of Epcam in breast cancer

S Shigdar, C Qian, L Lv, C Pu, Y Li, L Li, M Marappan, J Lin, L Wang, W Duan

(2013), Vol. 8, pp. 1-8, PLoS One, San Diego, United States, C1

Epithelial cell adhesion molecule (EpCAM) is associated with prostate cancer metastasis and chemo/radioresistance via the PI3K/Akt/mTOR signaling pathway

J Ni, P Cozzi, J Hao, J Beretov, L Chang, W Duan, S Shigdar, W Delprado, P Graham, J Bucci, J Kearsley, Y Li

(2013), Vol. 45, pp. 2736-2748, International journal of biochemistry and cell biology, Amsterdam, The Netherlands, C1

Inhibition of A/Human/Hubei/3/2005 (H3N2) influenza virus infection by silver nanoparticles in vitro and in vivo

D Xiang, Z Yang, W Duan, X Li, J Yin, S Shigdar, M O'Connor, M Marappan, X Zhao, Y Miao, B Xiang, C Zheng

(2013), Vol. 8, pp. 4103-4114, International Journal of Nanomedicine, Macclesfield, UK, C1

Inflammation and cancer stem cells

S Shigdar, Y Li, S Bhattacharya, M O'Connor, C Pu, J Lin, T Wang, D Xiang, L Kong, M Wei, Y Zhu, S Zhou, W Duan

(2013), Vol. 345, pp. 271-278, Cancer letters, Amsterdam, The Netherlands, C1

Aptamers as theranostic agents: modifications, serum stability and functionalisation

S Shigdar, J Macdonald, M O'Connor, T Wang, D Xiang, H Al.Shamaileh, L Qiao, M Wei, S Zhou, Y Zhu, L Kong, S Bhattacharya, C Li, W Duan

(2013), Vol. 13, pp. 13624-13637, Sensors, Basel, Switzerland, C1

Cancer stem cell targeting : the next generation of cancer therapy and molecular imaging

S Shigdar, J Lin, Y Li, C Yang, M Wei, Y Zhu, H Liu, W Duan

(2012), Vol. 3, pp. 227-244, Therapeutic delivery, London, England, C1

Enhanced antitumor efficacy and reduced systemic toxicity of sulfatide containing nanoliposomal doxorubicin in a xenograft model of colorectal cancer

J Lin, Y Yu, S Shigdar, D Fang, J Rong Du, M Wei, A Danks, K Liu, W Duan

(2012), Vol. 7, pp. 1-10, Plos One, San Francisco, Calif., C1-1

Role of the EpCAM (CD326) in prostate cancer metastasis and progression

J Ni, P Cozzi, W Duan, S Shigdar, P Graham, K John, Y Li

(2012), Vol. 31, pp. 779-791, Cancer metastasis reviews, New York, N. Y., C1

Groundwater pre-treatment prevents the onset of chronic ulcerative dermatopathy in juvenile Murray cod, Maccullochella peelii peelii (Mitchell)

A Schultz, S Shigdar, P Jones, A Ward, T Toop

(2011), Vol. 312, pp. 19-25, Aquaculture, Amsterdam, Netherlands, C1

Elevated levels of triglyceride and triglyceride-rich lipoprotein triglyceride induced by a high-carbohydrate diet is associated with polymorphisms of AP0A5-1131T>C and AP0C3-482C> in chinese healthy young adults

J Lin, D Fang, J Du, S Shigdar, L Xiao, X Zhou, W Duan

(2011), Vol. 58, pp. 150-157, Annals of nutrition and metabolism, Basel, Switzerland, C1

Clinical applications of aptamers and nucleic acid therapeutics in haematological malignancies

S Shigdar, A Ward, A De, C Yang, M Wei, W Duan

(2011), Vol. 155, pp. 3-13, British journal of haematology, Oxford, U. K., C1

RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule

S Shigdar, J Lin, Y Yu, M Pastuovic, M Wei, W Duan

(2011), Vol. 102, pp. 991-998, Cancer Science, Tokyo, Japan, C1-1

Aptamer therapeutics: the 21st century's magic bullet of nanomedicine

S Shigdar, J Luczo, M Wei, R Bell, A Danks, K Liu, D Wei

(2010), Vol. 1, pp. 118-124, Open conference proceedings journal, Bussum, The Netherlands, C1-1

TaqIB polymorphism in the CETP gene modulates the impact of HC/LF diet on the HDL profile in healthy Chinese young adults

J Du, D Fang, J Lin, L Xiao, X Zhou, S Shigdar, W Duan

(2010), Vol. 21, pp. 1114-1119, Journal of nutritional biochemistry, New York, N.Y., C1-1

Cytochemical characterisation of the leucocytes and thrombocytes from murray cod (Maccullochella peelii peelii, Mitchell)

S Shigdar, A Harford, A Ward

(2009), Vol. 26, pp. 731-736, Fish and shellfish immunology, Amsterdam, The Netherlands, C1

Functional interaction between mutations in the granulocyte colony-stimulating factor receptor in severe congenital neutropenia

A Ward, J Gits, F Majeed, A Aprikyan, R Lewis, L O`Sullivan, M Freedman, S Shigdar, I Touw, D Dale, Y Dror

(2008), Vol. 142, pp. 653-656, British journal of haematology, Oxford, England, C1

Blood cells of Murray cod maccullochella peelii peelii (Mitchell)

S Shigdar, D Cook, P Jones, A Harford, A Ward

(2007), Vol. 70, pp. 973-980, Journal of fish biology, Oxford, England, C1

The platelet glycoprotein Ia/IIa gene polymorphism C807T/G873A: a novel risk factor for retinal vein occlusion

P Dodson, J Haynes, J Starczynski, J Farmer, S Shigdar, G Fegan, R Johnson, C Fegan

(2003), Vol. 17, pp. 772-777, Eye, London, England, C1-1