Dr Torie Foletta



Research Fellow


Faculty of Health


School of Exercise & Nut. Sci.


Melbourne Burwood Campus


Doctor of Philosophy, Australian National University, 1996


Research interests

Dr Foletta is interested in characterizing specific molecular factors connecting skeletal muscle growth and metabolism. She uses a variety of molecular and cell biological techniques, genomics, proteomics and bioinformatics to obtain overviews of the molecules and signaling pathways involved in healthy and diseased states of skeletal muscle. Some of her current research projects involve the molecules NDRG2, PGC-1, ERRalpha, and the E3 ligases, atrogin-1/MAFbx and MuRF1.


Australian Physiological Society
Australian Society for Medical Research

Teaching interests

Supervises 1 PhD student
Co-supervises 2 PhD students


Foletta VC, McGee SL, Russell, AP. NDRG2, a putative tumour suppressor, increases ROS production and alters oxidative metabolism following its suppression in muscle cells. Oral Presentation. AussieMit 2012, Melbourne, 2012.

Foletta VC, Brown EL, Russell AP. Suppression of NDRG2, a novel PGC-1??? target gene, contributes to the metabolic profile and protein synthesis rates of skeletal muscle cells.  Oral presentation. AuPS/ASB/PSNZ Meeting, Sydney, 2012.

Foletta VC, McGee SL, Brown EL, Russell AP. NDRG2, a new effector of PGC-1 function in the control of skeletal muscle mass and metabolism.
Invited Speaker. Exercise, Muscle & Metabolism, Melbourne, 2011.

Foletta VC, Russell AP. NDRG2, a novel player in the control of skeletal muscle mass? Oral presentation. AuPS/ASB Meeting, Adelaide, 2010.

Foletta  VC, Cameron-Smith D, Walder K, Russell A. N-myc downstream-regulated gene 2 interacts with atrogin-1. A novel role for NDRG2 in skeletal muscle atrophy?
Oral presentation. Gage Muscle Conference, Canberra, ACT, 2010.

Professional activities

Dr Foletta is a regular reviewer for Metabolism, Clinical and Experimental, Molecular and Cellular Endocrinology, and Nutrition and Metabolism


Fellows’ Award for Research Excellence, National Institutes of Health (NIH)
Fogarty Visiting Fellows’ Award, National Institutes of Health (NIH)


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NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - but not palmitate-induced toxicity

Kimberley Anderson, Prof Aaron Russell, Dr Torie Foletta

(2015), Vol. 5, pp. 668-681, FEBS open bio, London, Eng., C1


Skeletal muscle mitochondria : a major player in exercise, health and disease.

Prof Aaron Russell, Dr Torie Foletta, Prof Rod Snow, Dr Glenn Wadley

(2014), Vol. 1840, pp. 1276-1284, Biochimica et Biophysica Acta - General Subjects, Amsterdam , Netherlands, C1


New gene targets of PGC-1α and ERRα co-regulation in C2C12 myotubes

Abena Nsiah-Sefaa, Miss Erin Brown, Prof Aaron Russell, Dr Torie Foletta

(2014), Vol. 41, pp. 8009-8017, Molecular biology reports, Amsterdam, The Netherlands, C1


Ndrg2 is a PGC-1cx/ERRcx target gene that controls protein synthesis and expression of contractile-type genes in C2C12 myotubes

Dr Torie Foletta, Miss Erin Brown, Yoshitake Cho, Prof Rod Snow, Anastasia Kralli, Prof Aaron Russell

(2013), Vol. 1833, pp. 3112-3123, Biochimica et Biophysica Acta - Molecular Cell Research, Amsterdam, Netherlands, C1


The role and regulation of MAFbx/atrogin-1 and MuRF1 in skeletal muscle atrophy

Dr Torie Foletta

(2011), Vol. 461, pp. 325-335, Pfluegers Archiv: European journal of physiology, Heidelberg, Germany, C1


Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1, a novel neuronal protein that regulates energy balance

James Trevaskis, Prof Ken Walder, Dr Torie Foletta, Ms Lyndal Bayles, Dr Janine Mc Millan, Mr Adrian Cooper

(2005), Vol. 146, pp. 3757-3764, Endocrinology, Philadelphia, Pa., C1-1