Dr Yann Gibert

STAFF PROFILE

Position

Senior Lecturer In Medical Biotechnology

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Qualifications

Doctor of Natural Sciences, University of Konstanz, 2005

Contact

y.gibert@deakin.edu.au
+61 3 522 71197

Biography

Dr. Yann Gibert obtained his BSc in Biology in 1997 from the University of Pau (France) and his MSc in Biochemistry in 2001 from the University of Limerick (Ireland). Dr. Gibert gained his PhD examining the roles played by the Retinoic Acid pathway during zebrafish embryonic development and using the zebrafish studied the evolution of genes implicated in non-channelopathy epilepsies in 2005 from the University of Konstanz (Germany).
After his PhD, Dr. Gibert worked as a post-doctoral fellow at the Institute of Functional Genomics of Lyon within the Ecole Normale Superieure of Lyon (France), broadening his interests into Retinoic Acid signalling and using the zebrafish as model for metabolic diseases. He then worked as a Research Fellow at Harvard Medical School, within the Beth Israel Deaconess Medical Centre, using the zebrafish to study the genetics of anemia and hemochromatosis.
Dr Gibert is the Head of the Metabolic Genetic Diseases Laboratory at Deakin School of Medicine (Australia). Dr Gibert’s team develop new techniques to study metabolism in vivo such as measuring metabolic respiration using the Seahorse Bio-analyzer and performing full lipidomic assay during vertebrate embryonic development using the zebrafish as model.

Read more on Yann's profile

Biography summary

1997 BSc, Major Biology University of Pau (France)

1999 Graduate Diploma, University of Limerick (Ireland)

2001 MSc in Biochemistry, University of Limerick (Ireland)

2005 PhD in Developmental Genetics, University of Konstanz (Germany)

2005-2007: Post-doctoral Fellow, Ecole Normale Superieure de Lyon (France)

2007-2010: Research Fellow, Harvard Medical School (Boston, MA, USA)

2010-2011: Reserach Assistant Professor, Tufts School of Medicine (Boston, MA, USA)

2011-present: Senior Lecturer, Head of the Metabolic Genetic Diseases Laboratory, Deakin School of Medicine (Australia)

Units taught

HMM102: Principles of Gene and Genomic Technology

HMM202: Molecular Diagnostics

Knowledge areas

Metabolism

Nuclear receptors biology

Zebrafish embryogenesis

Chemical Biology

Publications

Filter by

2017

The use of the zebrafish model to aid in drug discovery and target validation

P Yoganantharjah, Y Gibert

(2017), Vol. 17, pp. 2041-2055, Current topics in medicinal chemistry, Bussum, The Netherlands, C1

journal

Rapid quantification of neutral lipids and triglycerides during zebrafish embryogenesis

P Yoganantharajah, A Byreddy, D Fraher, M Puri, Y Gibert

(2017), Vol. 61, pp. 105-111, International journal of developmental biology, Vizcaya, Spain, C1

journal
2016

A comparison of novel organoiridium(III) complexes and their ligands as a potential treatment for prostate cancer.

S Hockey, G Barbante, P Francis, J Altimari, P Yoganantharajah, Y Gibert, L Henderson

(2016), Vol. 109, pp. 305-313, European journal of medicinal chemistry, Amsterdam, The Netherlands, C1

journal

Zebrafish embryonic lipidomic analysis reveals that the yolk cell as metabolically active in processing lipid

D Fraher, A Sanigorski, N Mellett, P Meikle, A Sinclair, Y Gibert

(2016), Vol. 14, pp. 1317-1329, Cell reports, Amsterdam, The Netherlands, C1

journal

Solvate ionic liquids as reaction media for electrocyclic transformations

D Eyckens, M Champion, B Fox, P Yoganantharajah, Y Gibert, T Welton, L Henderson

(2016), Vol. 2016, pp. 913-917, European journal of organic chemistry, London, Eng., C1

journal

A study on acute toxicity and solvent capacity of solvate ionic liquids: in vivo using a zebrafish model (Danio rerio)

P Yoganantharajah, D Eyckens, J Pedrina, L Henderson, Y Gibert

(2016), Vol. 40, pp. 6599-6603, New journal of chemistry, Cambridge, Eng., C1

journal
2015

ZebRA: an overview of retinoic acid signaling during zebrafish development.

E Samarut, D Fraher, V Laudet, Y Gibert

(2015), Vol. 1849, pp. 73-83, Biochimica et Biophysica Acta- gene regulatory mechanisms, Amsterdam, Netherlands, C1

journal

Altered retinoic acid signalling underpins dentition evolution

Y Gibert, E Samarut, E Pasco-Viel, L Bernard, V Borday-Birraux, A Sadier, C Labbé, L Viriot, V Laudet

(2015), Vol. 282, pp. 1-8, Proceedings of the royal society of London: biological sciences, London, Eng., C1

journal

Lipid abundance in zebrafish embryos is regulated by complementary actions of the endocannabinoid system and retinoic acid pathway

D Fraher, M Ellis, S Morrison, S McGee, A Ward, K Walder, Y Gibert

(2015), Vol. 156, pp. 3596-3609, Endocrinology, Bethesda, Md., C1

journal

Citalopram and sertraline exposure compromises embryonic bone development

D Fraher, J Hodge, F Collier, J McMillan, R Kennedy, M Ellis, G Nicholson, K Walder, S Dodd, M Berk, J Pasco, L Williams, Y Gibert

(2015), Vol. In press, pp. 1-9, Molecular psychiatry, Hampshire, Eng., C1

journal
2014

Rapid development of non-alcoholic steatohepatitis in Psammomys obesus (Israeli Sand Rat)

B Spolding, T Connor, C Wittmer, L Abreu, A Kaspi, M Ziemann, G Kaur, A Cooper, S Morrison, S Lee, A Sinclair, Y Gibert, J Trevaskis, J Roth, A El-Osta, R Standish, K Walder

(2014), Vol. 9, pp. 1-7, PLoS one, San Francisco, Calif., C1

journal

Estrogen-related receptor ? is an in vivo receptor of bisphenol A

M Tohmé, S Prud?homme, A Boulahtouf, E Samarut, F Brunet, L Bernard, W Bourguet, Y Gibert, P Balaguer, V Laudet

(2014), Vol. 28, pp. 3124-3133, FASEB journal, Bethesda, Md., C1

journal

Tissue specific roles for the Ribosome Biogenesis Factor Wdr43 in zebrafish development

C Zhao, V Andreeva, Y Gibert, M LaBonty, V Lattanzi, S Prabhudesai, Y Zhou, L Zon, K McCann, S Baserga, P Yelick

(2014), Vol. 10, pp. 1-15, PLoS genetics, San Francisco, Calif., C1-1

journal
2013

The small molecule, genistein, increases hepcidin expression in human hepatocytes

A Zhen, N Nguyen, Y Gibert, S Motola, P Buckett, M Wessling-Resnick, E Fraenkel, P Fraenkel

(2013), Vol. 58, pp. 1315-1325, Hepatology, Hoboken, N. J., C1

journal

Zebrafish as a genetic model in pre-clinical drug testing and screening

Y Gibert, M Trengove, A Ward

(2013), Vol. 20, pp. 2458-2466, Current Medicinal Chemistry, Hilversum, Netherlands, C1

journal

Metabolic profile analysis of zebrafish embryos

Y Gibert, S McGee, A Ward

(2013), Vol. 71, pp. 1-5, Journal of visualized experiments, Cambridge, Mass., C1

journal
2012

Retinoic acid expands the evolutionarily reduced dentition of zebrafish

P Seritrakul, E Samarut, T Lama, Y Gibert, V Laudet, W Jackman

(2012), Vol. 26, pp. 5014-5024, FASEB journal, Bethesda, Maryland, C1-1

journal

Fasting induces CART down-regulation in the zebrafish nervous system in a cannabinoid receptor 1-dependent manner

S Nishio, Y Gibert, L Berekelya, L Bernard, F Brunet, E Guillot, B Le, J Sanchez, A Galzin, G Triqueneaux, V Laudet

(2012), Vol. 26, pp. 1316-1326, Molecular endocrinology, Chevy Chase, Maryland, C1-1

journal
2011

Bisphenol A induces otolith malformations during vertebrate embryogenesis

Y Gibert, S Sassi-Messai, J Fini, L Bernard, D Zalko, J Cravedi, P Balaguer, M Andersson-Lendhal, B Demeneix, V Laudet

(2011), Vol. 11, pp. 1-17, BMC developmental biology, London, England, C1-1

journal

BMP signaling modulates hepcidin expression in zebrafish embryos independent of hemojuvelin

Y Gibert, V Lattanzi, A Zhen, L Vedder, F Brunet, S Fasse, J Babitt, H Lin, M Hammerschmidt, P Fraenkel

(2011), Vol. 6, pp. 1-14, PLoS one, San Francisco, California, C1-1

journal
2010

Formation of oral and pharyngeal dentition in teleosts depends on differential recruitment of retinoic acid signaling

Y Gibert, L Bernard, M Debiais-Thibaud, F Bourrat, J Joly, K Pottin, A Meyer, S Retaux, D Stock, W Jackman, P Seritrakul, G Begemann, V Laudet

(2010), Vol. 24, pp. 3298-3309, FASEB journal, Bethesda, Maryland, C1-1

journal
2009

Transferrin-a modulates hepcidin expression in zebrafish embryos

P Fraenkel, Y Gibert, J Holzheimer, V Lattanzi, S Burnett, K Dooley, R Wingert, L Zon

(2009), Vol. 113, pp. 2843-2850, Blood, Washington, DC, C1-1

journal

The phytoestrogen genistein affects zebrafish development through two different pathways

S Sassi-Messai, Y Gibert, L Bernard, S Nishio, L Ferri, J Molina, M Andersson-Lendhal, G Benoit, P Balaguer, V Laudet

(2009), Vol. 4, pp. 1-13, PLoS one, San Francisco, California, C1-1

journal
2008

Adiponectin and adiponectin receptor genes are coexpressed during zebrafish embryogenesis and regulated by food deprivation

S Nishio, Y Gibert, L Bernard, F Brunet, G Triqueneaux, V Laudet

(2008), Vol. 237, pp. 1682-1690, Developmental dynamics, Hoboken, N. J., C1-1

journal
2006

Induction and prepatterning of the zebrafish pectoral fin bud requires axial retinoic acid signaling

Y Gibert, A Gajewski, A Meyer, G Begemann

(2006), Vol. 133, pp. 2649-2659, Development, Cambridge, Eng., C1-1

journal
2005

Using gene-history and expression analyses to assess the involvement of LGI genes in human disorders

W Gu, Y Gibert, T Wirth, A Elischer, W Bloch, A Meyer, O Steinlein, G Begemann

(2005), Vol. 22, pp. 2209-2216, Molecular biology and evolution, Oxford, Eng., C1-1

journal

Analysis of the very large G-protein coupled receptor gene (Vlgr1/Mass1/USH2C) in zebrafish

Y Gibert, D McMillan, K Kayes-Wandover, A Meyer, G Begemann, P White

(2005), Vol. 353, pp. 200-206, Gene, Amsterdam, The Netherlands, C1-1

journal
2002

Cloning of zebrafish T-box genes tbx15 and tbx18 and their expression during embryonic development

G Begemann, Y Gibert, A Meyer, P Ingham

(2002), Vol. 114, pp. 137-141, Mechanisms of development, Amsterdam, The Netherlands, C1-1

journal
2001

Isolation and characterisation of the ylmE homologue of Thermus thermophilus

S Spada, Y Gibert, J Pembroke, J Wall

(2001), Vol. 11, pp. 507-514, Mitochondrial DNA, London, Eng., C1-1

journal

Cloning and characterisation of the hint homologue of the Thermophile Thermus thermophilus

Y Gibert, S Spada, J Wall, J Pembroke

(2001), Vol. 12, pp. 179-185, Mitochondrial DNA, London, Eng., C1-1

journal

Funded Projects at Deakin

Australian Competitive Grants

Roles of bisphenols A, S and AF in the development of diabetes and obesity

Dr Yann Gibert

DART Grant - Research - Diabetes Australia - Victoria (Research Trust)

  • 2014: $57,520

Industry and Other Funding

Automated gene expression quantification machine: qRT-PCR

Dr Yann Gibert, Prof Alister Ward

  • 2014: $33,800

Supervisions

Principal Supervisor
2015

Daniel Fraher

Thesis entitled: Chemical Modulators of Lipid Abundance and Bone Development

Doctor of Philosophy (Medicine), School of Medicine

Associate Supervisor
2015

Monique Trengove

Thesis entitled: Suppressor of cytokine signalling 4 and 5 in zebrafish development

Doctor of Philosophy (Medicine), School of Medicine

Carolyn Dancevic

Thesis entitled: Dissecting ADAMTS Proteoglycanase Biology in Development and Disease

Doctor of Philosophy (Medicine), School of Medicine