Dr Yann Gibert



Senior Lecturer In Medical Biotechnology


Faculty of Health


School of Medicine


Geelong Waurn Ponds Campus


+61 3 522 71197


Dr. Yann Gibert obtained his BSc in Biology in 1997 from the University of Pau (France) and his MSc in Biochemistry in 2001 from the University of Limerick (Ireland). Dr. Gibert gained his PhD examining the roles played by the Retinoic Acid pathway during zebrafish embryonic development and using the zebrafish studied the evolution of genes implicated in non-channelopathy epilepsies in 2005 from the University of Konstanz (Germany).
After his PhD, Dr. Gibert worked as a post-doctoral fellow at the Institute of Functional Genomics of Lyon within the Ecole Normale Superieure of Lyon (France), broadening his interests into Retinoic Acid signalling and using the zebrafish as model for metabolic diseases. He then worked as a Research Fellow at Harvard Medical School, within the Beth Israel Deaconess Medical Centre, using the zebrafish to study the genetics of anemia and hemochromatosis.
Dr Gibert is the Head of the Metabolic Genetic Diseases Laboratory at Deakin School of Medicine (Australia). Dr Gibert’s team develop new techniques to study metabolism in vivo such as measuring metabolic respiration using the Seahorse Bio-analyzer and performing full lipidomic assay during vertebrate embryonic development using the zebrafish as model.

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Biography summary

1997 BSc, Major Biology University of Pau (France)

1999 Graduate Diploma, University of Limerick (Ireland)

2001 MSc in Biochemistry, University of Limerick (Ireland)

2005 PhD in Developmental Genetics, University of Konstanz (Germany)

2005-2007: Post-doctoral Fellow, Ecole Normale Superieure de Lyon (France)

2007-2010: Research Fellow, Harvard Medical School (Boston, MA, USA)

2010-2011: Reserach Assistant Professor, Tufts School of Medicine (Boston, MA, USA)

2011-present: Senior Lecturer, Head of the Metabolic Genetic Diseases Laboratory, Deakin School of Medicine (Australia)

Units taught

HMM102: Principles of Gene and Genomic Technology

HMM202: Molecular Diagnostics

Knowledge areas


Nuclear receptors biology

Zebrafish embryogenesis

Chemical Biology


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A comparison of novel organoiridium(III) complexes and their ligands as a potential treatment for prostate cancer

Miss Samantha Hockey, Mr Gregory Barbante, Prof Paul Francis, Mr Jarrad Altimari, Mr Prusothman Yoganantharajah, Dr Yann Gibert, A/Prof Luke Henderson

(2016), Vol. 109, pp. 305-313, European journal of medicinal chemistry, Amsterdam, The Netherlands, C1


Solvate ionic liquids as reaction media for electrocyclic transformations

Mr Daniel James Eyckens, Ms Megan Champion, Prof Bronwyn Fox, Mr Prusothman Yoganantharajah, Dr Yann Gibert, Prof Tom Welton, A/Prof Luke Henderson

(2016), Vol. 2016, pp. 913-917, European journal of organic chemistry, London, Eng., C1


Citalopram and sertraline exposure compromises embryonic bone development

Mr Daniel Fraher, Dr Jason Hodge, Dr Fiona Collier, Ms Josephine Mcmillan, Richard L. Kennedy, Ms Megan Ellis, Geoff C. Nicholson, Prof Ken Walder, Dr Seetal Dodd, Prof Michael Berk, Prof Julie Pasco, A/Prof Lana Williams, Dr Yann Gibert

(2016), Vol. 21, pp. 656-664, Molecular psychiatry, London, Eng., C1


Zebrafish embryonic lipidomic analysis reveals that the yolk cell as metabolically active in processing lipid

Mr Daniel Fraher, Mr Andrew Sanigorski, Natalie Mellett, A/Prof Peter Meikle, Prof Andrew Sinclair, Dr Yann Gibert

(2016), Vol. 14, pp. 1317-1329, Cell reports, Amsterdam, The Netherlands, C1


A study on acute toxicity and solvent capacity of solvate ionic liquids: in vivo using a zebrafish model (Danio rerio)

Mr Prusothman Yoganantharajah, Mr Daniel James Eyckens, Ms Jessie Louise Pedrina, Dr Yann Gibert

(2016), Vol. 40, pp. 6599-6603, New journal of chemistry, Cambridge, Eng., C1


ZebRA: an overview of retinoic acid signaling during zebrafish development

Eric Samarut, Mr Daniel Fraher, Prof Vincent Laudet, Dr Yann Gibert

(2015), Vol. 1849, pp. 73-83, Biochimica et Biophysica Acta- gene regulatory mechanisms, Amsterdam, Netherlands, C1


Altered retinoic acid signalling underpins dentition evolution

Dr Yann Gibert, Eric Samarut, Emmanuel Pasco-Viel, Veronique Borday-Birraux, Alexa Sadier, Catherine Labbe, Laurent Viriot, Prof Vincent Laudet

(2015), Vol. 282, pp. 1-8, Proceedings of the royal society of London: biological sciences, London, Eng., C1


Lipid abundance in zebrafish embryos is regulated by complementary actions of the endocannabinoid system and retinoic acid pathway

Mr Daniel Fraher, Ms Megan Ellis, Ms Shona Morrison, A/Prof Sean Mcgee, Prof Alister Ward, Prof Ken Walder, Dr Yann Gibert

(2015), Vol. 156, pp. 3596-3609, Endocrinology, Bethesda, Md., C1


Tissue specific roles for the Ribosome Biogenesis Factor Wdr43 in zebrafish development

Chengtian Zhao, Viktoria Andreeva, Dr Yann Gibert, Melissa LaBonty, Victoria J. Lattanzi, Shubhangi Prabhudesai, Yi Zhou, Leonard I Zon, Kathleen L McCann, Susan Baserga, Pamela Yelick

(2014), Vol. 10, pp. 1-15, PLoS genetics, San Francisco, Calif., C1-1


Rapid development of non-alcoholic steatohepatitis in Psammomys obesus (Israeli Sand Rat)

Ms Briana Spolding, Mr Timothy Connor, Carrie Wittmer, Mrs Lelia Lelis Ferreira De Abreu, Antony Kaspi, Mark Ziemann, Dr Gunveen Kaur, Mr Adrian Cooper, Ms Shona Morrison, Mr Scott Lee, Prof Andrew Sinclair, Dr Yann Gibert, James Trevaskis, Jonathon Roth, A/Prof Assam El-Osta, Dr Richard Standish, Prof Ken Walder

(2014), Vol. 9, pp. 1-7, PLoS one, San Francisco, Calif., C1


Estrogen-related receptor γ is an in vivo receptor of bisphenol A

Marie Tohme, Sophie M. Prud`homme, Abdel Boulahtouf, Eric Samarut, Frederic Brunet, Laure Bernard, William Bourguet, Dr Yann Gibert, Patrick Balaguer, Prof Vincent Laudet

(2014), Vol. 28, pp. 3124-3133, FASEB journal, Bethesda, Md., C1


Metabolic profile analysis of zebrafish embryos

Dr Yann Gibert, A/Prof Sean Mcgee, Prof Alister Ward

(2013), Vol. 71, pp. 1-5, Journal of visualized experiments, Cambridge, Mass., C1


Zebrafish as a genetic model in pre-clinical drug testing and screening

Dr Yann Gibert, Dr Monique Trengove, Prof Alister Ward

(2013), Vol. 20, pp. 2458-2466, Current Medicinal Chemistry, Hilversum, Netherlands, C1


The small molecule, genistein, increases hepcidin expression in human hepatocytes

Aileen W Zhen, Nancy H Nguyen, Dr Yann Gibert, Shmulik Motola, Peter Buckett, Marinne Wessling-Resnick, Ernest Fraenkel, Paula G Fraenkel

(2013), Vol. 58, pp. 1315-1325, Hepatology, Hoboken, N. J., C1


Fasting induces CART down-regulation in the zebrafish nervous system in a cannabinoid receptor 1-dependent manner

Shin-Ichi Nishio, Dr Yann Gibert, Liubov Berekelya, Laure Bernard, Frederic Brunet, Etienne Guillot, Jean-Christophe Le Bail, Juan Antonio Sanchez, Anne Marie Galzin, Gerard Triqueneaux, Prof Vincent Laudet

(2012), Vol. 26, pp. 1316-1326, Molecular endocrinology, Chevy Chase, Maryland, C1-1


Retinoic acid expands the evolutionarily reduced dentition of zebrafish

Pawat Seritrakul, Eric Samarut, Tenzing T. S. Lama, Dr Yann Gibert, Prof Vincent Laudet, William R Jackman

(2012), Vol. 26, pp. 5014-5024, FASEB journal, Bethesda, Maryland, C1-1


Bisphenol A induces otolith malformations during vertebrate embryogenesis

Dr Yann Gibert, Sana Sassi-Messai, Jean-Baptiste Fini, Laure Bernard, Daniel Zalko, Jean-Pierre Cravedi, Patrick Balaguer, Monika Andersson-Lendhal, Barbara Demeneix, Prof Vincent Laudet

(2011), Vol. 11, pp. 1-17, BMC developmental biology, London, England, C1-1


BMP signaling modulates Hepcidin expression in zebrafish embryos independent of Hemojuvelin

Dr Yann Gibert, Victoria J. Lattanzi, Aileen W Zhen, Lea Vedder, Frederic Brunet, Sarah A Fasse, Jodie L Babitt, Herbert Y Lin, Matthias Hammerschmidt, Paula G Fraenkel

(2011), Vol. 6, pp. 1-14, PLoS one, San Francisco, California, C1-1


Formation of oral and pharyngeal dentition in teleosts depends on differential recruitment of retinoic acid signaling

Dr Yann Gibert, Laure Bernard, Melanie Debiais-Thibaud, Franck Bourrat, Jean-Stephane Joly, Karen Pottin, Axel Meyer, Sylvie Retaux, David W Stock, William R Jackman, Pawat Seritrakul, Gerrit Begemann, Prof Vincent Laudet

(2010), Vol. 24, pp. 3298-3309, FASEB journal, Bethesda, Maryland, C1-1


The phytoestrogen genistein affects zebrafish development through two different pathways

Sana Sassi-Messai, Dr Yann Gibert, Laure Bernard, Shin-Ichi Nishio, Karine F. Ferri Lagneau, Jose Molina, Monika Andersson-Lendhal, Gerard Benoit, Patrick Balaguer, Prof Vincent Laudet

(2009), Vol. 4, pp. 1-13, PLoS one, San Francisco, California, C1-1


Transferrin-a modulates hepcidin expression in zebrafish embryos

Paula G Fraenkel, Dr Yann Gibert, Jason L Holzheimer, Victoria J. Lattanzi, Sarah F Burnett, Kimberley A Dooley, Rebecca A Wingert, Leonard I Zon

(2009), Vol. 113, pp. 2843-2850, Blood, Washington, DC, C1-1


Adiponectin and adiponectin receptor genes are coexpressed during zebrafish embryogenesis and regulated by food deprivation

Shin-Ichi Nishio, Dr Yann Gibert, Liubov Berekelya, Laure Bernard, Frederic Brunet, Gerard Triqueneaux

(2008), Vol. 237, pp. 1682-1690, Developmental dynamics, Hoboken, N. J., C1-1


Induction and prepatterning of the zebrafish pectoral fin bud requires axial retinoic acid signaling

Dr Yann Gibert, Alexandra Gajewski, Axel Meyer, Gerrit Begemann

(2006), Vol. 133, pp. 2649-2659, Development, Cambridge, Eng., C1-1


Analysis of the very large G-protein coupled receptor gene (Vlgr1/Mass1/USH2C) in zebrafish

Dr Yann Gibert, D Randy McMillan, Kathleen Kayes-Wandover, Axel Meyer, Gerrit Begemann, Perrin White

(2005), Vol. 353, pp. 200-206, Gene, Amsterdam, The Netherlands, C1-1


Using gene-history and expression analyses to assess the involvement of LGI genes in human disorders

Wenli Gu, Dr Yann Gibert, Thierry Wirth, Andrea Elischer, Wilhelm Bloch, Alex Meyer, Ortrud Steinlein, Gerrit Begemann

(2005), Vol. 22, pp. 2209-2216, Molecular biology and evolution, Oxford, Eng., C1-1


Cloning of zebrafish T-box genes tbx15 and tbx18 and their expression during embryonic development

Gerrit Begemann, Dr Yann Gibert, Axel Meyer, Phillip Ingham

(2002), Vol. 114, pp. 137-141, Mechanisms of development, Amsterdam, The Netherlands, C1-1


Cloning and characterisation of the hint homologue of the Thermophile Thermus thermophilus

Dr Yann Gibert, Stefania Spada, J Gerard Wall, J Tony Pembroke

(2001), Vol. 12, pp. 179-185, Mitochondrial DNA, London, Eng., C1-1


Isolation and characterisation of the ylmE homologue of Thermus thermophilus

Stefania Spada, Dr Yann Gibert, J Tony Pembroke, J Gerard Wall

(2001), Vol. 11, pp. 507-514, Mitochondrial DNA, London, Eng., C1-1



Australian Competitive Grants

Roles of bisphenols A, S and AF in the development of diabetes and obesity

Dr Yann Gibert

DART Grant - Research - Diabetes Australia - Victoria (Research Trust)

  • 2014: $57,520

Industry and Other Funding

Automated gene expression quantification machine: qRT-PCR

Dr Yann Gibert, Prof Alister Ward

  • 2014: $33,800


Principal Supervisor

Daniel Fraher

Thesis entitled: Chemical Modulators of Lipid Abundance and Bone Development

Doctor of Philosophy (Medicine), School of Medicine

Associate Supervisor

Monique Trengove

Thesis entitled: Suppressor of cytokine signalling 4 and 5 in zebrafish development

Doctor of Philosophy (Medicine), School of Medicine

Carolyn Dancevic

Thesis entitled: Dissecting ADAMTS Proteoglycanase Biology in Development and Disease

Doctor of Philosophy (Medicine), School of Medicine