Staff profile

Prof Tiffany Walsh

Position: Professor Of Bionanotechnology
role description
Faculty or Division: Instit for Frontier Materials
Department: Instit for Frontier Materials
Campus: Geelong Waurn Ponds Campus
Phone: +61 3 522 73116 +61 3 522 73116
Email: tiffany.walsh@deakin.edu.au

Biography

Biography

Prof. Walsh's research interests and expertise focus on molecular modelling, chiefly of interfaces, using molecular dynamics simulations and first-principles calculations.

After graduating with a B.Sci(Hons) from the University of Melbourne, Prof. Walsh earned her PhD degree in theoretical chemistry from the University of Cambridge, U.K., working in the group of Prof. David Wales (FRS) in the Dept. of Chemistry, as a Cambridge Commonwealth Trust scholar. She then joined the Dept. of Materials, University of Oxford, U.K. as a postdoctoral researcher in the Materials Modelling Laboratory (MML) with Prof. Adrian Sutton (FRS). Staying in the MML, she held a Glasstone Fellowship, in addition to a Junior Research Fellowship at Linacre College, University of Oxford. Following this, she joined the faculty of the University of Warwick, U.K., as a joint appointment in the Dept. of Chemistry and the Centre for Scientific Computing. In 2012 she returned to Australia on a veski Innovation Fellowship and joined the Institute for Frontier Materials at Deakin University in Australia, where she currently holds the position of Professor of Bio/Nanotechnology.

Prof. Walsh was appointed to join the Australian Research Council (ARC) College of Experts in 2015.


Career highlights

2015 - current: Professor in Bio/Nanotechnology, Institute for Frontier Materials, Deakin University, Geelong, Australia

2012-2014 : Associate Professor in Bio/Nanotechnology, Institute for Frontier Materials, Deakin University, Geelong, Australia

2012-2015: veski Innovation Fellow

2002-2012: Associate Professor in Computational & Theoretical Chemistry, Dept. of Chemistry and Centre for Scientific Computing, University of Warwick, Coventry, U.K

2000-2002: Glasstone Fellow in Dept. of Materials and Junior Research Fellow at Linacre College, Materials Modelling Laboratory, Dept. of Materials, University of Oxford, Oxford, U.K

1998-2000: Postdoctoral Research Associate, Materials Modelling Laboratory, Dept. of Materials, University of Oxford, Oxford, U.K


Affiliations

Adjunct Associate Professor, University of Warwick, U.K.

Adjunct Associate Professor, University at Buffalo, SUNY, U.S.A


LinkedIn profile

https://www.linkedin.com/in/tiffany-walsh-14302114


Research

Research projects

Recent Projects:

Molecular Simulations of Blood Protein Therapeutics. Consultancy, funded by CSL Ltd. (2015-2016).

Integration of Experiment and Modelling to Advance Biosensor Design based on Conformational Switching of Surface-Adsorbed Nucleic Acids. Funded by the Asian Office of Aerospace Research & Development (AFOSR Tokyo Office), (2016-2018).

Modelling the Elastic and Barrier Properties of Skin: Investigation of Keratin Self-Organization at the Molecular Level. Funded by Unilever R&D, Port Sunlight, UK. (2011-2014)

Bio-nanocombinatorics to Achieve Precisely-Assembled Multicomponent, Functional Hybrid Nanomaterials. Grant #FA9550-12-1-0226. Funded by the Air Force Office for Scientific Research (U.S.A). (2012-2017)

Aiding Developments in Advanced Materials Funded by veski.  (2012-2015)

Bioinspired Interfaces for Improved Carbon Fibre Composite Performance. Funded by the Australian Research Council.(2014-2016)


Research interests


  • Materials modelling of bio/nano interfaces, principally at the molecular level, to make connections between molecular scale details and macroscopic properties.

  • Development of efficient molecular simulation approaches for the meaningful study of self-assembly of large biomolecules and their structure-function relationships.

  • Application of these approaches to investigate problems ranging from the directed biomolecule-mediated assembly of inorganic nanoparticles, through to modeling the mechanical response of keratin fibres in skin in the presence of molecular additives.


Research grants

1. Bio-nanocombinatorics to Achieve Precisely-Assembled Multicomponent, Functional Hybrid Nanomaterials (Consortium-based, TRW as Aus. Lead CI). Grant #FA9550-12-1-0226. RM25045, funded by the Air Force Office for Scientific Research (U.S.A). This is a 5-year grant funding a postdoctoral research associate (level A) at 100% FTE.

2. Aiding Developments in Advanced Materials (TRW, Lead CI). RM24666, funded by veski. This is a 3-year grant funding a postdoctoral research associate (level A) at 100% FTE.


Publications

Publications

Selected Recent Publications:

N. M. Bedford, Z. E. Hughes, Z. Tang, Y. Li, B. D. Briggs, Y. Ren, M .T. Swihart, V. G. Petkov, R. R. Naik, M. R. Knecht,  T. R. Walsh*,  J. Amer. Chem. Soc. , 138, 540 (2016) [IF=12.1]  "Sequence-Dependent Structure/Function Relationships of Catalytic Peptide-Enabled Au Nanoparticles Generated Under Ambient Synthetic Conditions"

B. Demir and T. R. Walsh*, Soft Matter, 12, 2453-2464 (2016) [IF=4.0]. "A robust and reproducible procedure for cross-linking thermoset polymers using molecular simulation"

L. B. Wright, J. P. Palafox-Hernandez, P. M. Rodger, S. Corni and T. R. Walsh*, Chem. Sci., 6, 5204-5214 (2015). [IF=9.2] "Facet selectivity in gold binding peptides: exploiting interfacial water structure"

J. P. Palafox-Hernandez, C.-K. Lim, Z. Tang, K. L. M. Drew, Z. E. Hughes, Y. Li,  M. T. Swihart, P. N Prasad, M. R. Knecht and T. R. Walsh*, ACS Appl. Mater. Inter., 8, 1050-1060 (2016). [IF=6.7] "Optical Actuation of Inorganic/Organic Interfaces: Comparing Peptide-Azobenzene Ligand Reconfiguration on Gold and Silver Nanoparticles"

G. O. Rutter, A. H. Brown, D. Quigley*, T. R. Walsh and M. P. Allen, Phys. Chem. Chem. Phys., 17, 31741-31749 (2015).  [IF=4.5] "Testing the transferability of a coarse-grained model to intrinsically disordered proteins".

Z. Tang, C.-K. Lim, J. P. Palafox-Hernandez, K. L. M. Drew, Y. Li,  M. T. Swihart, P. N. Prasad*, T. R. Walsh* and M. R. Knecht, Nanoscale, 7, 13638-13645 (2015). [IF=7.4]  "Triggering Nanoparticle Surface Ligand Rearrangement via External Stimuli: Light-based Actuation of Biointerfaces"

D. J. Bray, T. R. Walsh*, M. G. Noro and R. Notman, PLoS One, 10, e0132706-1-22, (2015). [IF=3.2] "Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly"


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