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SLE346 - Molecular Basis of Disease

Unit details

Year2018 unit information
Enrolment modes:Trimester 2: Burwood (Melbourne), Waurn Ponds (Geelong)
Credit point(s):1
EFTSL value:0.125
Unit chair:

Agnes Michalczyk


SLE212 and one of SLE206, SLE211, SLE222 or SLE214



Incompatible with:


Contact hours:

3 x 1 hour class per week, 4 x 3 hour practicals per trimester, 1 x 3 hour seminar per trimester


Molecular Basis of Disease is the study of the pathology of human disease at a molecular and cellular level. Building on previous knowledge of biology and chemistry, students will learn general principles of cell pathology and examine the molecular and cellular changes that lead to diverse clinical features seen in inherited syndromes and multisystem diseases. Fundamental concepts including toxic damage to cells, repair process within cells, cell ageing and mechanisms of cell death will be addressed in this unit. Students will apply knowledge of these fundamental concepts to study common disorders including cancer, diabetes and brain disease as well as explore how the environment can influence disease and the role of trace elements in human biology. During classes students will be exposed to current theories of the molecular basis of disease through articles from the primary scientific literature. In practical sessions, students will learn essential laboratory skills that will enable them to investigate some key concepts in cell biology and their relevance to diagnostic medicine.


2 x in-class tests (10% each) 20%, practical reports 35%, group presentation 5%, examination 40%

Unit Fee Information

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