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Associate Professor Aaron Russell is a Senior Lecturer and National Health and Medical Research Council (NHMRC) Biomedical CDA Research Fellow in the Centre for Physical Activity and Nutrition Research (C-PAN), within the School of Exercise and Nutrition Sciences. He supervises and co-supervisors a number of PhD students. Associate Professor Russell is an active researcher, focusing on determining the molecular factors that control skeletal muscle wasting, growth and regeneration.
Supervisor of 5 PhD students
Co-Supervisor of 2 PhD students
Associate Professor Russell’s research group is focused on determining the molecular factors that control skeletal muscle wasting, growth and regeneration. Investigations are performed human using in vivo models of muscle wasting including ALS, COPD, sarcopenia, and immobilization. Acute and chronic exercise protocols are used as models to investigate the signalling proteins which regulate skeletal muscle growth and regeneration. In vitro studies are also performed using human primary muscle cells as well as C2C12 and L6 muscle cell lines.
Research tools include quantitative PCR, Western blotting, EMSA, Luciferase reporter assays, protein degradation and synthesis assays, glucose uptake assays, adenoviral infections and ChIP.
Molecular targets of interest include Akt, atrogin-1/MAFBX, FoXO, G-CSF, MuRF1, PGC-1, SRF and STARS
2009 – Deakin University Award for Research Excellence
2008 - NHMRC Biomedical Career Development Award. “Molecular
targets involved in human muscle atrophy and hypertrophy.”
2003 - Best oral presentation.3rd Swiss Interfaculty Conference of Sport and Health, November 2003, Lausanne, Switzerland. “Endurance training in humans leads to fibre type-specific increases in skeletal muscle αlevels of PGC-1α and PPAR.”
Australia Physiological Society (2007-present)
National Association of Research Fellows (2008-present)
Associate Professor Russell is a Member of the School Research Committee and sits on the Executive Committee of C-PAN. He is also co-coordinator of the HDR program, and sits on the University Animal Welfare Committee.
Associate Professor Russell regularly reviews for American Journal of Physiology, European Journal of Applied Physiology, FASEB J, International Journal of Obesity, Journal of Physiology, Journal of Clinical Investigation and Physiological Genomics.
(Invited presentation - past 5 years)
The Gage- Curtain Muscle Conference, Canberra Australia, “PGC-1α regulates protein synthesis and growth related microRNAs: a potential target for combating muscle wasting”, April 14th-16th, 2010.
Australian Physiological Society Conference (AuPS), Melbourne Australia, Symposium Presentation, “Molecular mechanisms regulating muscle mass”, Nov 30th- Dec 10th 2008.
3rd Australian Association for Exercise and Sports Science (AAESS) Conference, Melbourne Australia. “Molecular Modelling of Muscle Mass”, 27th-30th March, 2008.
Exercise, Muscle and Metabolism Conference, Melbourne, Australia. “Molecular regulation of skeletal muscle mass”. November 14-16, 2007.
Swiss Foundation for Aging Research, Geneva, Switzerland. “Regulation of genes and signalling pathways involved in human muscle atrophy during aging”, March 2006.