This thesis aims to compare the Comprehensive Quality of Life scale, an Australian QoL measure, with a depression inventory yet to be determined in screening for depression within a general population. Current research indicates that there is a recognised need for a holistic instrument capable of measuring both depression and satisfaction. It is hypothesised that the ComQol scale has the ability to indicate depression within the community as well as indicating the domain or area of life that is linked with the depression in the individual. Therefore, this research has important implications for the treatment of depression in that the ComQol may prove important in planning and evaluating treatment strategies.