Dr Bernhard Dichtl
  Phone   +61 3 925 17060
Email   bernhard.dichtl@deakin.edu.au
Position   Lecturer
Campus   Burwood
Research grouping   Biomolecular Sciences

Most cellular processes depend on large protein complexes. We are interested in how such protein
assemblies work and how their activities are regulated. In particular we study protein machines involved
in chromatin modification and RNA processing. Intriguingly, next to nothing is known about the formation
of these complexes inside the cell. Recent results from our research support a model for
co-translational complex formation and surveillance.

Research interests

  1. RNA processing and disease
  2. Histone modification and chromatin structure
  3. Assembly of large protein complexes


Career

Lecturer, Deakin University
Research group leader, University of Zurich, Switzerland
Postdoctoral Fellow, University of Basel, Switzerland
PhD, EMBL Heidelberg and University of Edinburgh

Key publications

Mariconti, L., Loll, B., Schlinkmann, K., Wengi, A., Meinhart, A. and Dichtl, B. (2010) Coupled RNA polymerase II transcription and 3' end formation with yeast whole-cell extracts RNA 16(11), 2205-2217

Halbach, A., Zhang, H., Wengi, A., Jablonska, Z., Gruber, IM., Halbeisen, RE., Dehe, PM., Kemmeren, P., Holstege, F., Geli, V., Gerber, AP. and Dichtl, B. (2009) Cotranslational assembly of the yeast SET1C histone methyltransferase complex The EMBO Journal 28(19), 2959-2970

Holbein, S., Wengi, A., Decourty, L., Freimoser, FM., Jacquier, A. and Dichtl, B. (2009) Cordycepin interferes with 3' end formation in yeast independently of its potential to terminate RNA chain elongation RNA 15(5), 837-849

Dichtl, B., Aasland, R. and Keller, W. (2004) Functions for S. cerevisiae Swd2 in 3' end formation of specific mRNAs and snoRNAs and global histone 3 lysine 4 methylation RNA 10(6), 965-977

Dichtl, B., Blank, D., Sadowski, M., Hubner, W., Weiser, S. and Keller, W. (2002) A role for SSU72 in balancing RNA polymerase II transcription elongation and termination Molecular Cell 10(5), 1139-1150

View entire list of audited publications

Professional activities

Member Faculty of 1000
Member of the RNA Society
Member of Swiss Society for Cell Biology, Molecular Biology and Genetics
Reviewer for grant agencies
Ad Hoc reviewer for various journals

 

Postdoctoral fellows

NameProject title
Dr Beatriz DichtlRegulation and assembly of the Set1C histone methyltransferase  

 

Teaching areas

Biochemistry


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22nd September 2011