Assoc Prof Cenk Suphioglu

   Phone   +61 3 522 72886
Email   cenk.suphioglu@deakin.edu.au
Position   Associate Head of School (Development)
Campus   Geelong
Research grouping   Biomolecular Sciences

Economic cost and burden of allergy is significant worldwide, which can be difficult to manage and can
prove fatal. The focus of my NeuroAllergy Research Laboratory (NARL) is to study the environmental
and molecular biology of allergens and the allergic reaction, and identify novel inhibitors for allergy
prevention and treatment. In addition, we study the importance of omega-3 fatty acids in human neuronal
cell survival to develop novel intervention strategies for neurodegenerative diseases.

Research interests

  1. Pollen and nut allergy: molecular analysis and novel intervention strategies
  2. Grass pollen triggered thunderstorm asthma
  3. Importance of omega-3 fatty acids in brain cell survival


Career

Deakin University (2006-present)
Monash University (1998-2006)
The University of Melbourne (1990-1998)

Key publications

Sadli N, Ackland ML, De Mel D, Sinclair AJ, Suphioglu C. (2012) Effects of zinc and DHA on the epigenetic regulation of human neuronal cells. Cellular Physiology and Biochemistry 29(1-2), 87-98.

Suphioglu C, Sadli N, Coonan D, Kumar L, De Mel D, Lesheim J, Sinclair A, Ackland ML. (2010) Zinc and DHA have opposing effects on the expression levels of histones H3 and H4 in human neuronal cells. British Journal of Nutrition 103(3), 344-51.

de Leon MP, Glaspole IN, Drew AC, Rolland JM, O'Hehir RE, Suphioglu C. (2003) Immunological analysis of allergenic cross-reactivity between peanut and tree nuts. Clinical and Experimental Allergy 33(9), 1273-80.

Sutherland MF, O'Hehir RE, Czarny D, Suphioglu C. (1999) Macadamia nut anaphylaxis: demonstration of specific IgE reactivity and partial cross-reactivity with hazelnut. Journal of Allergy and Clinical Immunology 104, 889-90.

Suphioglu C, Singh MB, Taylor PE, Bellomo R, Holmes P, Puy R, Knox RB. (1992) Mechanism of grass pollen-induced asthma The Lancet 339, 569-72.

View entire list of audited publications

Professional activities

Reviewer, Journal of Allergy and Clinical Immunology (JACI); Clinical and Experimental Allergy (CEA)
Assessor, NHMRC and ARC Grants
Member, American Academy of Allergy Asthma and Immunology (AAAAI); European Academy of Allergy and Clinical Immunology (EAACI)
Full Member, Australasian Society of Clinical Immunology and Allergy (ASCIA); Australasian Society for Immunology (ASI)
Member, Australian Society for Medical Research (ASMR)

Related links

Thunderstorm asthma ABC Catalyst TV interview (14 April 2011)
www.abc.net.au/catalyst/storie s/3191776.htm

Peanut allergy Deakin interview (01 March 2010)
www.deakin.edu.au/scitech/abou t/news/archive/2010/index.php# peanuts

Peanut allergy ABC National Radio interview (10 February 2010)
www.abc.net.au/pm/content/2010 /s2815963.htm

 

PhD students

Student nameThesis title
Nayyar AhmedCharacterisation of a novel IL-4 receptor antagonist for allergy treatment Pathum DhanapalaProduction and characterization of hypoallergenic chicken eggs (with Prof Tim Doran from the Poultry CRC/AAHL/CSIRO) Dwan PriceMolecular and immunological analysis of food allergens Justin Leagh ReadHuman β-secretase (BACE1) as a novel Alzheimer’s disease (AD) intervention target Nadia SadliZinc and omega-3 fatty acid metabolism in brain cells – links to Alzheimer’s disease  

 

Honours students

Student nameThesis title Chamika De Silva (2012)Cloning and recombinant expression analysis of the major egg white allergen, ovalbumin Jessica Kukucka (2011/2012)Identification of novel synthetic peptide inhibitors for human deacetylase 1 (HDAC1) for Alzheimer's disease treatment Lauren Mahoney (2012)Human IL-13 receptor as a novel allergy intervention target Tessa Wyllie (2011/2012)Characterisation of inhibitors of phosphoinositide 3-kinase for allergy treatment  

 

Teaching areas

Allergy
Developmental Biology
Medical Microbiology and Immunology
Microbiology



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22nd September 2011