Assoc Prof Cenk Suphioglu |
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| Economic cost and burden of allergy is significant worldwide, which can be difficult to manage and can prove fatal. The focus of my NeuroAllergy Research Laboratory (NARL) is to study the environmental and molecular biology of allergens and the allergic reaction, and identify novel inhibitors for allergy prevention and treatment. In addition, we study the importance of omega-3 fatty acids in human neuronal cell survival to develop novel intervention strategies for neurodegenerative diseases. Research interests
CareerDeakin University (2006-present)Monash University (1998-2006) The University of Melbourne (1990-1998) Key publicationsSadli N, Ackland ML, De Mel D, Sinclair AJ, Suphioglu C. (2012) Effects of zinc and DHA on the epigenetic regulation of human neuronal cells. Cellular Physiology and Biochemistry 29(1-2), 87-98.Suphioglu C, Sadli N, Coonan D, Kumar L, De Mel D, Lesheim J, Sinclair A, Ackland ML. (2010) Zinc and DHA have opposing effects on the expression levels of histones H3 and H4 in human neuronal cells. British Journal of Nutrition 103(3), 344-51. de Leon MP, Glaspole IN, Drew AC, Rolland JM, O'Hehir RE, Suphioglu C. (2003) Immunological analysis of allergenic cross-reactivity between peanut and tree nuts. Clinical and Experimental Allergy 33(9), 1273-80. Sutherland MF, O'Hehir RE, Czarny D, Suphioglu C. (1999) Macadamia nut anaphylaxis: demonstration of specific IgE reactivity and partial cross-reactivity with hazelnut. Journal of Allergy and Clinical Immunology 104, 889-90. Suphioglu C, Singh MB, Taylor PE, Bellomo R, Holmes P, Puy R, Knox RB. (1992) Mechanism of grass pollen-induced asthma The Lancet 339, 569-72. View entire list of audited publications Professional activitiesReviewer, Journal of Allergy and Clinical Immunology (JACI); Clinical and Experimental Allergy (CEA)Assessor, NHMRC and ARC Grants Member, American Academy of Allergy Asthma and Immunology (AAAAI); European Academy of Allergy and Clinical Immunology (EAACI) Full Member, Australasian Society of Clinical Immunology and Allergy (ASCIA); Australasian Society for Immunology (ASI) Member, Australian Society for Medical Research (ASMR) Related linksThunderstorm asthma ABC Catalyst TV interview (14 April 2011)www.abc.net.au/catalyst/storie s/3191776.htm Peanut allergy Deakin interview (01 March 2010) www.deakin.edu.au/scitech/abou t/news/archive/2010/index.php# peanuts Peanut allergy ABC National Radio interview (10 February 2010) www.abc.net.au/pm/content/2010 /s2815963.htm PhD studentsStudent nameThesis titleNayyar AhmedCharacterisation of a novel IL-4 receptor antagonist for allergy treatment Pathum DhanapalaProduction and characterization of hypoallergenic chicken eggs (with Prof Tim Doran from the Poultry CRC/AAHL/CSIRO) Dwan PriceMolecular and immunological analysis of food allergens Justin Leagh ReadHuman β-secretase (BACE1) as a novel Alzheimer’s disease (AD) intervention target Nadia SadliZinc and omega-3 fatty acid metabolism in brain cells – links to Alzheimer’s disease Honours studentsStudent nameThesis title Chamika De Silva (2012)Cloning and recombinant expression analysis of the major egg white allergen, ovalbumin Jessica Kukucka (2011/2012)Identification of novel synthetic peptide inhibitors for human deacetylase 1 (HDAC1) for Alzheimer's disease treatment Lauren Mahoney (2012)Human IL-13 receptor as a novel allergy intervention target Tessa Wyllie (2011/2012)Characterisation of inhibitors of phosphoinositide 3-kinase for allergy treatmentTeaching areasAllergyDevelopmental Biology Medical Microbiology and Immunology Microbiology |
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