Faculty of Science, Engineering and Built Environment

School of Life and Environmental Sciences

Dr Paul Stevenson
  Phone   N/A
Email   paul.stevenson@deakin.edu.au
Position   Alfred Deakin Postdoctoral Research Fellow
Campus   Geelong
Research grouping   Chemistry and Forensic Sciences

Dr Paul Stevenson has been a research fellow at Deakin University since May 2012 where his research
focus is on the separation of very complex chemical mixtures that are extracted from natural sources.
It is being realised that for samples of highly complexity two-dimensional high performance liquid
chromatography (2D-HPLC) is superior than conventional one dimensional HPLC. By taking advantage
of dimensionality in the sample matrix 2D-HPLC can increase the number of compounds that are
isolated, hence information, about the sample. Dr Stevenson has a strong interest in developing
methods for diverse range of separation problems to gain as much information from a single
experiment as possible and has had experience developing separation conditions for samples of
coffee, algae and peptide digests.

Dr Stevenson's other research interest is in the analysis of the complex 2D-HPLC data sets that 2D-
HPLC separations generate. There is a shortage of software solutions available to the analyst
performing multidimensional separations, with the best software packages merely drawing a three
dimensional profile of the separation. Dr Stevenson has developed an application that quickly and
reliably identifies the coordinates of peaks in the two dimensional separation space. This is a useful
tool for the analyst as the information gained can be used as a finger print for quality control of food
and/or drugs, or to track changes in growth patterns of biological samples, to name a couple of
examples.

Research interests

  1. Multidimensional high performance liquid chromatography (2D-HPLC)
  2. 2D-HPLC data analysis
  3. Separation of complex chemical mixtures


Career

2012 to date: Alfred Deakin Postdoctoral Research Fellow at Deakin University, Waurn Ponds Campus, Vic, Australia
2010 to 2012: Research Associcate II at the University of Tennessee (UT), Knoxville, TN, USA
2007 to 2010: PhD candidate at the University of Western Sydney (UWS), Parramatta, NSW, Australia

Key publications

P.G. Stevenson, M. Mnatsakanyan, G. Guiochon and R.A. Shalliker (2010) Peak Picking and the Assessment of Separation Performance in Two-Dimensional High Performance Liquid Chromatography Analyst 135, 1541-1550

P.G. Stevenson, F. Gritti, G. Guiochon (2011) Automated methods for the location of the boundaries of chromatographic peaks Journal of chromatography A 1218, 8255-8263

P.G. Stevenson, S. Kayillo, G.R. Dennis, R.A. Shalliker (2007) Effects of π‐π Interactions on the Separation of PAHs on Phenyl‐Type Stationary Phases Journal of Liquid Chromatography & Related Technologies 31, 324-347

P.G. Stevenson, X.A. Conlan, N.W. Barnett (2013) Evaluation of the asymmetric least squares baseline algorithm through the accuracy of statistical peak moments Journal of Chromatography A 1284, 107–111

F. Gritti, I. Leonardis, D. Shock, P. Stevenson, A. Shalliker, G. Guiochon (2010) Performance of columns packed with the new shell particles, Kinetex-C18 Journal of chromatography A 1217, 1589-1603

View entire list of audited publications

 

PhD students

Student nameThesis title
Danielle BassaneseMaximising Capacity in Complex Separation Systems  

 

Teaching areas

SLE 213: Introduction to multidimensional high performance liquid chromaotgraphy
SLE 316: Multidimensional hight performance liquid chromatography separation optimisation


Deakin University acknowledges the traditional land owners of present campus sites.

8th February 2013