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Dr Luke Henderson
I was awarded my PhD in synthetic organic chemistry in 2008 from Griffith University, QLD. My PhD
project involved the total synthesis of the hyphodermin family of compounds which had shown unique
antidiabetes activity targetting glycogen phosphorylase A.
Loughlin, W. A.; Jenkins, I. D.; Henderson, L. C.; Campetelli, M. C.; Healy, P. C; J. Org. Chem. 2008,
73 (9), 3435 – 3440.
I have held two postdoctoral positions, the first was at the University of Oxford, UK. I worked on the
synthesis of Indoles using tandem reaction approach mediated by Buchwald-Hartwig chemistry, under the
supervision of Dr. Michael Willis.
Henderson, Luke C.; Lindon, Matthew J.; Willis, Michael C. Tetrahedron 2010, 66 (33), 6632-6638
The second was and Alfred Deakin Postdotoral Fellowship at Deakin University, working on the development
of novel antibiotics based on the naturally occurring compound Colistin, under the supervision of Dr.
Henderson, Luke C.; Li, Jian; Nation, Roger L.; Velkov, Tony; Pfeffer, Frederick
Chem.Commun. (Cambridge, United Kingdom) 2010, 46 (18), 3197-3199.
Since the conclusion of this position I have remained at Deakin University as a research fellow
developing an independent research profile, recently being appointed Senior Lecturer of Organic and
Materials Chemistry with the Institute for Frontier Materials.
My research interests are very broad and include areas of medicinal chemistry, materials chemistry and
CareerSenior Lecturer of Organic and Materials Chemistry
Alfred Deakin Postdoctoral Research Fellow
Postdoctoral Research Fellow (Oxford UK)
Key publicationsLuke C. Henderson,* Joshua P. Delaney. (2012) Direct Asymmetric Aldol Reactions in Water Catalysed by a Highly Active C2-Symmetric Bisprolinamide Organocatalyst Advanced Synthesis & Catalysis 354 (1), 197-204. Wiley & Sons
Luke C. Henderson,* Jarrad M. Altimari, Linden Servinis, Gail Dyson, Birunthi Niranjan and Gail. P. Risbridger (2011) A Comparative Assessment of α-Lipoic Acid N-phenylamides as Androgen Receptor Antagonists both on and off Gold Nanoparticles Bioorganic Chemistry 40, 1-5 Elsevier
Megan T. Thornton, Luke C. Henderson,* Nolene Byrne, Frederick M. Pfeffer (2012) Accessing highly-halogenated flavanones using protic ionic liquids and microwave irradiation. Current Organic Chemistry 16 (1), 121-126 Bentham Scientific
Jennifer S. Squire, Luke C. Henderson,* Xavier A. Conlan* (2012) Synthesis and comparative physical-chemical characterisation of neutral and cationic amphiphiles using RP-HPLC Current Analytical Chemistry Accepted for pulblication,
Joshua P. Delaney, Luke C. Henderson* (2011) Investigating ionic effects applied to water based organocatalysed aldol reactions Int. J. Mol. Sci. 12, 9083-9094
View entire list of audited publications
Professional activitiesReviewer for the Australian Research Council
Member of the RACI
PhD studentsStudent nameThesis title
Jarrad AltimariA Nanomedical Approach to Prostate Cancer Treatment Joshua DelaneyDevelopent of Novel C2-symmetric Organocatalysts Linden ServinisFunctionalisation of Carbon Fibers for Advanced Materials Jennifer SquireSynthesis and Physicochemical Evaluation of Kinked Amphiphiles
Honours studentsStudent nameThesis title Luke AndrighettoDiazonium Functionalisation of Carbon Fibers for Enhanced Fiber-Matrix Adhesion Hannah BrozinskiApplication of C2-Symmetric Organocatalysts to Organic Transformations in Water Kelsey WaughA Dual Tiered Therapy for Targetting Breast Cancer