A/Prof. Alyssa Barry

STAFF PROFILE

Position

Professor, Systems Epidemiology of Infection

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Contact

a.barry@deakin.edu.au
+61 3 522 73504

Biography

Alyssa Barry is Professor of Systems Epidemiology of Infection with Deakin University’s Institute for Physical and Mental Health and Clinical Translation (IMPACT) and Head of the Translational Genomics Working Group, Burnet Institute where some of her team is based.

Alyssa has been Chief Investigator on six NHMRC Project Grants (four as CIA) and is a Technical Director of a DFAT IndoPacific Centre for Health Security grant supporting the development of molecular surveillance capacity in Papua New Guinea. She leads genomics research in two NIH-funded International Centres for Excellence in Malaria Research (ICEMR) programs in Asia-Pacific and West Africa. She is also a member of the Australian Centre of Research Excellence in Malaria Elimination (ACREME), the Asia Pacific Malaria Elimination Network (APMEN) and the Malaria Genomic Epidemiology Network (MalariaGEN). 

Read more on Alyssa's profile

Career highlights

NHMRC/Royal Society Howard Florey Postdoctoral Fellow (2001-3)

NHMRC Howard Florey Centenary Fellow (2006-8)

veski Innovation Fellow (2006)

Georgina Sweet Award for Women in Quantitative Biosciences (2017)

Affiliations

Honourary Principal Research Fellow, Burnet Instiute, Melbourne

Knowledge areas

infectious diseases, malaria, genetics, genomics, immunology, epidemiology, population studies

Projects

Alyssa's research seeks to understand the complex dynamic that exists between host, pathogen and environment that contributes to patterns of exposure, infection and disease. The research explores systems biology on a population level using well-characterised epidemiological studies and has a strong translational focus.

Current projects include:

(i) malaria parasite genomic surveillance to understand transmission dynamics and antimalarial drug resistance and how they change in response to interventions;

(ii) characterising malaria vaccine candidate diversity and how this contributes to immune escape;

(iii) understanding how immunity develops to diverse malaria parasites;

(iv) identifying host and parasite factors contributing to asymptomatic malaria;

(v) metagenomics of Buruli ulcer;

(vi) systems epidemiology of COVID-19 in Western Victoria

The group is using cutting edge technologies to characterise pathogens and their hosts, combining this information with epidemiological data and advanced analytical approaches (bioinformatics, population genetics and biostatistics) to answer key questions in malaria biology and epidemiology. Our work is informing strategies for infectious disease control and elimination including stratification of control efforts, diagnostics, drugs and vaccines.

We work closely with a large network of local and international collaborators including field researchers and malaria control programs. We frequently host trainees for advanced molecular training.

Alyssa’s Deakin/Burnet co-appointment aims to strengthen and expand collaboration in genomics, infectious diseases and microbiome research across the two organisations.

Publications

Filter by

2022

Population-level genome-wide STR discovery and validation for population structure and genetic diversity assessment of Plasmodium species

J Han, J Munro, A Kocoski, A Barry, M Bahlo

(2022), Vol. 18, PLoS Genetics, C1

journal article

Global diversity and balancing selection of 23 leading Plasmodium falciparum candidate vaccine antigens

M Naung, E Martin, J Munro, S Mehra, A Guy, M Laman, G Harrison, L Tavul, M Hetzel, D Kwiatkowski, I Mueller, M Bahlo, A Barry

(2022), Vol. 18, PLoS Computational Biology, C1

journal article

STRIVE PNG: using a partnership-based approach in implementation research to strengthen surveillance and health systems in Papua New Guinea

R Farquhar, A Dori, S MacCana, N Tefuarani, E Lavu, A Barry, S Karl, L Makita, L Robinson, M Laman

(2022), Vol. 20, pp. 2-10, Health research policy and systems, London, England, C1

journal article
2021

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

A Ahouidi, M Ali, J Almagro-Garcia, A Amambua-Ngwa, C Amaratunga, R Amato, L Amenga-Etego, B Andagalu, T Anderson, V Andrianaranjaka, T Apinjoh, C Ariani, E Ashley, S Auburn, G Awandare, H Ba, V Baraka, A Barry, P Bejon, G Bertin, M Boni, S Borrmann, T Bousema, O Branch, P Bull, G Busby, T Chookajorn, K Chotivanich, A Claessens, D Conway, A Craig, U D'Alessandro, S Dama, N Day, B Denis, M Diakite, A Djimdé, C Dolecek, A Dondorp, C Drakeley, E Drury, P Duffy, D Echeverry, T Egwang, B Erko, R Fairhurst, A Faiz, C Fanello, M Fukuda, D Gamboa, A Ghansah, L Golassa, S Goncalves, W Hamilton, G Harrison, L Hart, C Henrichs, T Hien, C Hill, A Hodgson, C Hubbart, M Imwong, D Ishengoma, S Jackson, C Jacob, B Jeffery, A Jeffreys, K Johnson, D Jyothi, C Kamaliddin, E Kamau, M Kekre, K Kluczynski, T Kochakarn, A Konaté, D Kwiatkowski, M Kyaw, P Lim, C Lon, K Loua, O Maïga-Ascofaré, C Malangone, M Manske, J Marfurt, K Marsh, M Mayxay, A Miles, O Miotto, V Mobegi, O Mokuolu, J Montgomery, I Mueller, P Newton, T Nguyen, T Nguyen, H Noedl, F Nosten, R Noviyanti, A Nzila, L Ochola-Oyier

(2021), Vol. 6, pp. 1-31, Wellcome Open Research, London, England, C1

journal article

Whole-genome analysis of Malawian Plasmodium falciparum isolates identifies possible targets of allele-specific immunity to clinical malaria

Z Shah, M Naung, K Moser, M Adams, A Buchwald, A Dwivedi, A Ouattara, K Seydel, D Mathanga, A Barry, D Serre, M Laufer, J Silva, S Takala-Harrison

(2021), Vol. 17, pp. 1-20, PLoS genetics, San Francisco, Calif., C1

journal article

Community-based molecular and serological surveillance of subclinical malaria in Myanmar

K O’Flaherty, W Oo, S Zaloumis, J Cutts, K Aung, M Thein, D Drew, Z Razook, A Barry, N Parischa, N Zaw, H Thu, A Thi, W Htay, A Soe, J Simpson, J Beeson, P Agius, F Fowkes

(2021), Vol. 19, pp. 1-12, BMC Medicine, London, Eng., C1

journal article

Surveillance of molecular markers of Plasmodium falciparum artemisinin resistance (kelch13 mutations) in Papua New Guinea between 2016 and 2018

D Lautu-Gumal, Z Razook, T Koleala, E Nate, S McEwen, D Timbi, M Hetzel, E Lavu, N Tefuarani, L Makita, J Kazura, I Mueller, W Pomat, M Laman, L Robinson, A Barry

(2021), Vol. 16, pp. 188-193, International Journal for Parasitology: Drugs and Drug Resistance, Amsterdam, The Netherlands, C1

journal article
2020

A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice

A Valencia-Hernandez, W Ng, N Ghazanfari, S Ghilas, M de Menezes, L Holz, C Huang, K English, M Naung, P Tan, K Tullett, T Steiner, M Enders, L Beattie, Y Chua, C Jones, A Cozijnsen, V Mollard, Y Cai, D Bowen, A Purcell, N La Gruta, J Villadangos, T de Koning-Ward, A Barry, W Barchet, I Cockburn, G McFadden, S Gras, M Lahoud, P Bertolino, R Schittenhelm, I Caminschi, W Heath, D Fernandez-Ruiz

(2020), Vol. 27, pp. 950-962, Cell Host and Microbe, Amsterdam, The Netherlands, C1

journal article

The epidemiology of Plasmodium falciparum and Plasmodium vivax in East Sepik Province, Papua New Guinea, pre- and post-implementation of national malaria control efforts

J Kattenberg, D Gumal, M Ome-Kaius, B Kiniboro, M Philip, S Jally, B Kasian, N Sambale, P Siba, S Karl, A Barry, I Felger, J Kazura, I Mueller, L Robinson

(2020), Vol. 19, pp. 1-18, Malaria journal, London, Eng., C1

journal article

Population genomics identifies a distinct Plasmodium vivax population on the China-Myanmar border of Southeast Asia

Awtum Brashear, Qi Fan, Yubing Hu, Yuling Li, Yan Zhao, Zenglei Wang, Yaming Cao, Jun Miao, Alyssa Barry, Liwang Cui

(2020), Vol. 14, pp. 1-23, PLOS Neglected Tropical Diseases, San Francisco, Calif., C1

journal article

Evaluation of the effectiveness of topical repellent distributed by village health volunteer networks against Plasmodium spp. infection in Myanmar: A stepped-wedge cluster randomised trial

P Agius, J Cutts, W Oo, A Thi, K O’Flaherty, K Aung, H Thu, P Aung, M Thein, N Zaw, W Min Htay, A Soe, Z Razook, A Barry, W Htike, A Devine, J Simpson, B Crabb, J Beeson, N Pasricha, F Fowkes

(2020), Vol. 17, pp. 1-21, PLoS Medicine, San Francisco, CA, C1

journal article

SNP barcodes provide higher resolution than microsatellite markers to measure Plasmodium vivax population genetics

A Fola, E Kattenberg, Z Razook, D Lautu-Gumal, S Lee, S Mehra, M Bahlo, J Kazura, L Robinson, M Laman, I Mueller, A Barry

(2020), Vol. 19, pp. 1-15, Malaria journal, London, Eng., C1

journal article

Monitoring plasmodium falciparum and plasmodium vivax using microsatellite markers indicates limited changes in population structure after substantial transmission decline in Papua New Guinea

J Kattenberg, Z Razook, R Keo, C Koepfli, C Jennison, D Lautu-Gumal, A Fola, M Ome-Kaius, C Barnadas, P Siba, I Felger, J Kazura, I Mueller, L Robinson, A Barry

(2020), Vol. 29, pp. 4525-4541, Molecular ecology, Chichester, Eng., C1

journal article

Emergence of artemisinin-resistant Plasmodium falciparum with kelch13 C580Y mutations on the island of New Guinea

O Miotto, M Sekihara, S Tachibana, M Yamauchi, R Pearson, R Amato, S Gonçalves, S Mehra, R Noviyanti, J Marfurt, S Auburn, R Price, I Mueller, M Ikeda, T Mori, M Hirai, L Tavul, M Hetzel, M Laman, A Barry, P Ringwald, J Ohashi, F Hombhanje, D Kwiatkowski, T Mita

(2020), Vol. 16, pp. 1-21, PLoS Pathogens, San Francisco, CA, C1

journal article
2019

Differential impact of malaria control interventions on P. falciparum and P. vivax infections in young Papua New Guinean children

M Ome-Kaius, J Kattenberg, S Zaloumis, M Siba, B Kiniboro, S Jally, Z Razook, D Mantila, D Sui, J Ginny, A Rosanas-Urgell, S Karl, T Obadia, A Barry, S Rogerson, M Laman, D Tisch, I Felger, J Kazura, I Mueller, L Robinson

(2019), Vol. 17, pp. 1-13, BMC Medicine, London, Eng., C1

journal article

Protective Immunity against Severe Malaria in Children Is Associated with a Limited Repertoire of Antibodies to Conserved PfEMP1 Variants

S Tessema, R Nakajima, A Jasinskas, S Monk, L Lekieffre, E Lin, B Kiniboro, C Proietti, P Siba, P Felgner, D Doolan, I Mueller, A Barry

(2019), Vol. 26, pp. 579-590.e5, Cell Host and Microbe, New York, N.Y., C1

journal article

Molecular epidemiology of residual Plasmodium vivax transmission in a paediatric cohort in Solomon Islands

Y Quah, A Waltmann, S Karl, M White, V Vahi, A Darcy, F Pitakaka, M Whittaker, D Tisch, A Barry, C Barnadas, J Kazura, I Mueller

(2019), Vol. 18, pp. 1-15, Malaria Journal, London, Eng., C1

journal article
2018

Identity-by-descent analyses for measuring population dynamics and selection in recombining pathogens

L Henden, S Lee, I Mueller, A Barry, M Bahlo

(2018), Vol. 14, pp. 1-31, PLoS Genetics, San Francisco, Calif., C1

journal article

Increasingly inbred and fragmented populations of Plasmodium vivax associated with the eastward decline in malaria transmission across the Southwest Pacific

A Waltmann, C Koepfli, N Tessier, S Karl, A Fola, A Darcy, L Wini, G Harrison, C Barnadas, C Jennison, H Karunajeewa, S Boyd, M Whittaker, J Kazura, M Bahlo, I Mueller, A Barry

(2018), Vol. 12, pp. 1-21, PLoS Neglected Tropical Diseases, San Francisco, Calif., C1

journal article

Antibodies to intercellular adhesion molecule 1-binding Plasmodium falciparum erythrocyte membrane protein 1-DBLβ are biomarkers of protective immunity to malaria in a cohort of young children from Papua New Guinea

S Tessema, D Utama, O Chesnokov, A Hodder, C Lin, G Harrison, J Jespersen, B Petersen, L Tavul, P Siba, D Kwiatkowski, T Lavstsen, D Hansen, A Oleinikov, I Mueller, A Barry

(2018), Vol. 86, pp. 1-14, Infection and Immunity, Washington, D.C., C1

journal article

Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study

O Mitjà, C Godornes, W Houinei, A Kapa, R Paru, H Abel, C González-Beiras, S Bieb, J Wangi, A Barry, S Sanz, Q Bassat, S Lukehart

(2018), Vol. 391, pp. 1599-1607, The Lancet, London, Eng., C1

journal article

Nationwide genetic surveillance of Plasmodium vivax in Papua New Guinea reveals heterogeneous transmission dynamics and routes of migration amongst subdivided populations

A Fola, E Nate, G Abby Harrison, C Barnadas, M Hetzel, J Iga, P Siba, I Mueller, A Barry

(2018), Vol. 58, pp. 83-95, Infection, Genetics and Evolution, Amsterdam, The Netherlands, C1

journal article
2017

Development of a Multilocus Sequence Typing (MLST) scheme for Treponema pallidum subsp. pertenue: Application to yaws in Lihir Island, Papua New Guinea

C Godornes, L Giacani, A Barry, O Mitja, S Lukehart

(2017), Vol. 11, pp. 1-20, PLoS Neglected Tropical Diseases, San Francisco, Calif., C1

journal article

Sustained malaria control over an 8-year period in Papua New Guinea: The challenge of low-density asymptomatic plasmodium infections

C Koepfli, M Ome-Kaius, S Jally, E Malau, S Maripal, J Ginny, L Timinao, J Kattenberg, T Obadia, M White, P Rarau, N Senn, A Barry, J Kazura, I Mueller, L Robinson

(2017), Vol. 216, pp. 1434-1443, Journal of Infectious Diseases, Oxford, Eng., C1

journal article

Challenges for achieving safe and effective radical cure of Plasmodium vivax: a round table discussion of the APMEN Vivax Working Group

K Thriemer, B Ley, A Bobogare, L Dysoley, M Alam, A Pasaribu, J Sattabongkot, E Jambert, G Domingo, R Commons, S Auburn, J Marfurt, A Devine, M Aktaruzzaman, N Sohel, R Namgay, T Drukpa, S Sharma, E Sarawati, I Samad, M Theodora, S Nambanya, S Ounekham, R Mudin, G Da Thakur, L Makita, R Deray, S Lee, L Boaz, M Danansuriya, S Mudiyanselage, N Chinanonwait, S Kitchakarn, J Nausien, E Naket, T Duc, H Do Manh, Y Hong, Q Cheng, J Richards, R Kusriastuti, A Satyagraha, R Noviyanti, X Ding, W Khan, C Swe Phru, Z Guoding, G Qi, A Kaneko, O Miotto, W Nguitragool, W Roobsoong, K Battle, R Howes, A Roca-Feltrer, S Duparc, I Bhowmick, E Kenangalem, J Bibit, A Barry, D Sintasath, R Abeyasinghe, C Sibley, J McCarthy, L Von Seidlein, J Baird, R Price

(2017), Vol. 16, pp. 1-9, Malaria Journal, London, Eng., C1

journal article

Higher complexity of infection and genetic diversity of plasmodium vivax than plasmodium falciparum across all malaria transmission zones of Papua New Guinea

A Fola, G Harrison, M Hazairin, C Barnadas, M Hetzel, J Iga, P Siba, I Mueller, A Barry

(2017), Vol. 96, pp. 630-641, American Journal of Tropical Medicine and Hygiene, Northbrook, Ill., C1

journal article

Dissecting malaria biology and epidemiology using population genetics and genomics

S Auburn, A Barry

(2017), Vol. 47, pp. 77-85, International Journal for Parasitology, Amsterdam, The Netherlands, C1

journal article
2016

Population genomics studies identify signatures of global dispersal and drug resistance in Plasmodium vivax

D Hupalo, Z Luo, A Melnikov, P Sutton, P Rogov, A Escalante, A Vallejo, S Herrera, M Arévalo-Herrera, Q Fan, Y Wang, L Cui, C Lucas, S Durand, J Sanchez, G Christian Baldeviano, A Lescano, M Laman, C Barnadas, A Barry, I Mueller, J Kazura, A Eapen, D Kanagaraj, N Valecha, M Ferreira, W Roobsoong, W Nguitragool, J Sattabonkot, D Gamboa, M Kosek, J Vinetz, L González-Cerón, B Birren, D Neafsey, J Carlton

(2016), Vol. 48, pp. 953-958, Nature Genetics, London, Eng., C1

journal article

Genomic analysis of local variation and recent evolution in Plasmodium vivax

R Pearson, R Amato, S Auburn, O Miotto, J Almagro-Garcia, C Amaratunga, S Suon, S Mao, R Noviyanti, H Trimarsanto, J Marfurt, N Anstey, T William, M Boni, C Dolecek, H Tran, N White, P Michon, P Siba, L Tavul, G Harrison, A Barry, I Mueller, M Ferreira, N Karunaweera, M Randrianarivelojosia, Q Gao, C Hubbart, L Hart, B Jeffery, E Drury, D Mead, M Kekre, S Campino, M Manske, V Cornelius, B MacInnis, K Rockett, A Miles, J Rayner, R Fairhurst, F Nosten, R Price, D Kwiatkowski

(2016), Vol. 48, pp. 959-964, Nature Genetics, London, Eng., C1

journal article

Implications of Plasmodium vivax biology for control, elimination, and research

P Olliaro, J Barnwell, A Barry, K Mendis, I Mueller, J Reeder, G Shanks, G Snounou, C Wongsrichanalai

(2016), Vol. 95, pp. 4-14, American Journal of Tropical Medicine and Hygiene, Northbrook, Ill., C1

journal article

Spatial effects on the multiplicity of Plasmodium falciparum infections

S Karl, M White, G Milne, D Gurarie, S Hay, A Barry, I Felger, I Mueller

(2016), Vol. 11, pp. 1-20, PLoS ONE, San Francisco, Calif., C1

journal article

Genomic epidemiology of artemisinin resistant malaria

R Amato, O Miotto, C Woodrow, J Almagro-Garcia, I Sinha, S Campino, D Mead, E Drury, M Kekre, M Sanders, A Amambua-Ngwa, C Amaratunga, L Amenga-Etego, V Andrianaranjaka, T Apinjoh, E Ashley, S Auburn, G Awandare, V Baraka, A Barry, M Boni, S Borrmann, T Bousema, O Branch, P Bull, K Chotivanich, D Conway, A Craig, N Day, A Djimdé, C Dolecek, A Dondorp, C Drakeley, P Duffy, D Echeverry, T Egwang, R Fairhurst, A Faiz, C Fanello, T Hien, A Hodgson, M Imwong, D Ishengoma, P Lim, C Lon, J Marfurt, K Marsh, M Mayxay, P Michon, V Mobegi, O Mokuolu, J Montgomery, I Mueller, M Kyaw, P Newton, F Nosten, R Noviyanti, A Nzila, H Ocholla, A Oduro, M Onyamboko, J Ouedraogo, A Phyo, C Plowe, R Price, S Pukrittayakamee, M Randrianarivelojosia, P Ringwald, L Ruiz, D Saunders, A Shayo, P Siba, S Takala-Harrison, T Thanh, V Thathy, F Verra, J Wendler, N White, H Ye, V Cornelius, R Giacomantonio, D Muddyman, C Henrichs, C Malangone, D Jyothi, R Pearson, J Rayner, G McVean, K Rockett, A Miles, P Vauterin, B Jeffery, M Manske, J Stalker, B Macinnis, D Kwiatkowski

(2016), Vol. 5, pp. 1-1, eLife, Cambridge, Eng., C1

journal article

Structurally conserved erythrocyte-binding domain in Plasmodium provides a versatile scaffold for alternate receptor engagement

J Gruszczyk, N Lim, A Arnott, W He, W Nguitragool, W Roobsoong, Y Mok, J Murphy, K Smith, S Lee, M Bahlo, I Mueller, A Barry, W Tham

(2016), Vol. 113, pp. E191-E200, Proceedings of the National Academy of Sciences of the United States of America, Irvine, Calif., C1

journal article
2015

Malaria Molecular Epidemiology: Lessons from the International Centers of Excellence for Malaria Research Network

A Escalante, M Ferreira, J Vinetz, S Volkman, L Cui, D Gamboa, D Krogstad, A Barry, J Carlton, A van Eijk, K Pradhan, I Mueller, B Greenhouse, M Pacheco, A Vallejo, S Herrera, I Felger

(2015), Vol. 93, pp. 79-86, The American journal of tropical medicine and hygiene, Northbrook, Ill., C1

journal article

Designing malaria vaccines to circumvent antigen variability

A Ouattara, A Barry, S Dutta, E Remarque, J Beeson, C Plowe

(2015), Vol. 33, pp. 7506-7512, Vaccine, Amsterdam, The Netherlands, C1

journal article

High Rates of Asymptomatic, Sub-microscopic Plasmodium vivax Infection and Disappearing Plasmodium falciparum Malaria in an Area of Low Transmission in Solomon Islands

A Waltmann, A Darcy, I Harris, C Koepfli, J Lodo, V Vahi, D Piziki, G Shanks, A Barry, M Whittaker, J Kazura, I Mueller

(2015), Vol. 9, pp. 1-18, PLoS Neglected Tropical Diseases, San Francisco, Calif., C1

journal article

Blood-stage parasitaemia and age determine Plasmodium falciparum and P. vivax gametocytaemia in Papua New Guinea

C Koepfli, L Robinson, P Rarau, M Salib, N Sambale, R Wampfler, I Betuela, W Nuitragool, A Barry, P Siba, I Felger, I Mueller

(2015), Vol. 10, pp. 1-15, PLoS ONE, San Francisco, Calif., C1

journal article

Uncovering the transmission dynamics of Plasmodium vivax using population genetics

A Barry, A Waltmann, C Koepfli, C Barnadas, I Mueller

(2015), Vol. 109, pp. 142-152, Pathogens and Global Health, London, Eng., C1

journal article

Plasmodium vivax Populations Are More Genetically Diverse and Less Structured than Sympatric Plasmodium falciparum Populations

C Jennison, A Arnott, N Tessier, L Tavul, C Koepfli, I Felger, P Siba, J Reeder, M Bahlo, I Mueller, A Barry

(2015), Vol. 9, pp. 1-20, PLoS Neglected Tropical Diseases, San Francisco, Calif., C1

journal article

Phylogeography of var gene repertoires reveals fine-scale geospatial clustering of Plasmodium falciparum populations in a highly endemic area

S Tessema, S Monk, M Schultz, L Tavul, J Reeder, P Siba, I Mueller, A Barry

(2015), Vol. 24, pp. 484-497, Molecular Ecology, London, Eng., C1

journal article
2014

How molecular epidemiology studies can support the National Malaria Control Program in Papua New Guinea

C Koepfli, A Barry, S Javati, L Timinao, E Nate, I Mueller, C Barnadas

(2014), Vol. 57, pp. 75-85, Papua and New Guinea medical journal, Port Moresby, New Guinea, C1-1

journal article

Limited antigenic diversity of Plasmodium falciparum apical membrane antigen 1 supports the development of effective multi-allele vaccines

U Terheggen, D Drew, A Hodder, N Cross, C Mugyenyi, A Barry, R Anders, S Dutta, F Osier, S Elliott, N Senn, D Stanisic, K Marsh, P Siba, I Mueller, J Richards, J Beeson

(2014), Vol. 12, pp. 1-20, BMC Medicine, London, Eng., C1-1

journal article

Strategies for designing and monitoring malaria vaccines targeting diverse antigens

A Barry, A Arnott

(2014), Vol. 5, pp. 1-16, Frontiers in Immunology, Lausanne, Switzerland, C1-1

journal article

Distinct patterns of diversity, population structure and evolution in the AMA1 genes of sympatric Plasmodium falciparum and Plasmodium vivax populations of Papua New Guinea from an area of similarly high transmission

A Arnott, J Wapling, I Mueller, P Ramsland, P Siba, J Reeder, A Barry

(2014), Vol. 13, pp. 1-16, Malaria Journal, London, ENg., C1-1

journal article

Genetic diversity of VAR2CSA ID1-DBL2Xb in worldwide Plasmodium falciparum populations: Impact on vaccine design for placental malaria

B Bordbar, N Tuikue Ndam, E Renard, S Jafari-Guemouri, L Tavul, C Jennison, S Gnidehou, R Tahar, D Gamboa, J Bendezu, D Menard, A Barry, P Deloron, A Sabbagh

(2014), Vol. 25, pp. 81-92, Infection, Genetics and Evolution, Amsterdam, The Netherlands, C1-1

journal article
2013

Global Population Structure of the Genes Encoding the Malaria Vaccine Candidate, Plasmodium vivax Apical Membrane Antigen 1 (PvAMA1)

A Arnott, I Mueller, P Ramsland, P Siba, J Reeder, A Barry

(2013), Vol. 7, pp. 1-14, PLoS Neglected Tropical Diseases, San Francisco, Calif., C1-1

journal article

High genetic diversity of plasmodium vivax on the north coast of papua new guinea

A Arnott, C Barnadas, N Senn, P Siba, I Mueller, J Reeder, A Barry

(2013), Vol. 89, pp. 188-194, American Journal of Tropical Medicine and Hygiene, [Northbrook, Ill.], C1-1

journal article

A Large Plasmodium vivax Reservoir and Little Population Structure in the South Pacific

C Koepfli, L Timinao, T Antao, A Barry, P Siba, I Mueller, I Felger

(2013), Vol. 8, pp. 1-9, PLoS ONE, San Francisco, Calif., C1-1

journal article

High levels of genetic diversity of Plasmodium falciparum populations in Papua New Guinea despite variable infection prevalence

A Barry, L Schultz, N Senn, J Nale, B Kiniboro, P Siba, I Mueller, J Reeder

(2013), Vol. 88, pp. 718-725, American Journal of Tropical Medicine and Hygiene, [Northbrook, Ill.], C1-1

journal article

Escaping the immune system: How the malaria parasite makes vaccine development a challenge

D Stanisic, A Barry, M Good

(2013), Vol. 29, pp. 612-622, Trends in Parasitology, Amsterdam, The Netherlands, E1-1

conference
2012

Using population genetics to guide malaria vaccine design

Alyssa Barry, James Beeson, John Reeder, F Fowkes, A Arnott

(2012), pp. 231-264, Malaria Parasites, Rijeka, Croatia, B1-1

book chapter

Hepatitis C Virus Phylogenetic Clustering Is Associated with the Social-Injecting Network in a Cohort of People Who Inject Drugs

R Sacks-Davis, G Daraganova, C Aitken, P Higgs, L Tracy, S Bowden, R Jenkinson, D Rolls, P Pattison, G Robins, J Grebely, A Barry, M Hellard

(2012), Vol. 7, pp. 1-15, PLoS ONE, San Francisco, Calif., C1-1

journal article

The Plasmodium falciparum Erythrocyte Invasion Ligand Pfrh4 as a Target of Functional and Protective Human Antibodies against Malaria

L Reiling, J Richards, F Fowkes, D Wilson, W Chokejindachai, A Barry, W Tham, J Stubbs, C Langer, J Donelson, P Michon, L Tavul, B Crabb, P Siba, A Cowman, I Mueller, J Beeson

(2012), Vol. 7, pp. 1-12, PLoS ONE, San Francisco, Calif., C1-1

journal article

Understanding the population genetics of Plasmodium vivax is essential for malaria control and elimination

A Arnott, A Barry, J Reeder

(2012), Vol. 11, pp. 1-10, Malaria Journal, London, Eng., C1-1

journal article
2011

The stability and complexity of antibody responses to the major surface antigen of Plasmodium falciparum are associated with age in a malaria endemic area

A Barry, A Trieu, F Fowkes, J Pablo, M Kalantari-Dehaghi, A Jasinskas, X Tan, M Kayala, L Tavul, P Siba, K Day, P Baldi, P Felgner, D Doolan

(2011), Vol. 10, pp. 1-13, Molecular and Cellular Proteomics, Bethesda, Md., C1-1

journal article

Population genetic analysis of the Plasmodium falciparum 6-cys protein Pf38 in Papua New Guinea reveals domain-specific balancing selection

J Reeder, J Wapling, I Mueller, P Siba, A Barry

(2011), Vol. 10, pp. 1-9, Malaria Journal, London, Eng., C1-1

journal article

A molecular epidemiological study of var gene diversity to characterize the reservoir of Plasmodium falciparum in humans in Africa

D Chen, A Barry, A Leliwa-Sytek, T Smith, I Peterson, S Brown, F Migot-Nabias, P Deloron, M Kortok, K Marsh, J Daily, D Ndiaye, O Sarr, S Mboup, K Day

(2011), Vol. 6, pp. 1-12, PLoS ONE, San Francisco, Calif., C1-1

journal article
2010

Multilocus haplotypes reveal variable levels of diversity and population structure of Plasmodium falciparum in Papua New Guinea, a region of intense perennial transmission

L Schultz, J Wapling, I Mueller, P Ntsuke, N Senn, J Nale, B Kiniboro, C Buckee, L Tavul, P Siba, J Reeder, A Barry

(2010), Vol. 9, pp. 1-12, Malaria Journal, London, Eng., C1-1

journal article

Evidence that the erythrocyte invasion ligand PfRh2 is a target of protective immunity against Plasmodium falciparum malaria

L Reiling, J Richards, F Fowkes, A Barry, T Triglia, W Chokejindachai, P Michon, L Tavul, P Siba, A Cowman, I Mueller, J Beeson

(2010), Vol. 185, pp. 6157-6167, Journal of Immunology, Bethesda, Md., C1-1

journal article
2009

Contrasting population structures of the genes encoding ten leading vaccine-candidate antigens of the human malaria parasite, Plasmodium falciparum

A Barry, L Schultz, C Buckee, J Reeder

(2009), Vol. 4, pp. 1-11, PLoS ONE, San Francisco, Calif., C1-1

journal article
2007

Genomic heterogeneity in the density of noncoding single-nucleotide and microsatellite polymorphisms in Plasmodium falciparum

S Volkman, E Lozovsky, A Barry, T Bedford, L Bethke, A Myrick, K Day, D Hartl, D Wirth, S Sawyer

(2007), Vol. 387, pp. 1-6, Gene, Amsterdam, The Netherlands, C1-1

journal article

Population genomics of the immune evasion (var) genes of Plasmodium falciparum

A Barry, A Leliwa-Sytek, L Tavul, H Imrie, F Migot-Nabias, S Brown, G McVean, K Day

(2007), Vol. 3, pp. 1-9, PLoS Pathogens, San Francisco, Calif., C1-1

journal article
2006

Variable SNP density in aspartyl-protease genes of the malaria parasite Plasmodium falciparum

A Barry, A Leliwa-Sytek, K Man, J Kasper, D Hartl, K Day

(2006), Vol. 376, pp. 163-173, Gene, Amsterdam, The Netherlands, C1-1

journal article
2005

Malaria epidemiology: Insights from the genome of the malaria parasite

Alyssa Barry

(2005), Vol. 1, pp. 76-86, Journal of Molecular and Genetic Medicine, Oxford, Eng., C1-1

journal article
2003

DNA sequence artifacts and the estimation of time to the most recent common ancestor (TMRCA) of Plasmodium falciparum

A Barry, A Leliwa, M Choi, K Nielsen, D Hartl, K Day

(2003), Vol. 130, pp. 143-147, Molecular and Biochemical Parasitology, Amsterdam, The Netherlands, C1-1

journal article
2002

The paradoxical population genetics of Plasmodium falciparum

D Hartl, S Volkman, K Nielsen, A Barry, K Day, D Wirth, E Winzeler

(2002), Vol. 18, pp. 266-272, Trends in Parasitology, Amsterdam, The Netherlands, C1-1

journal article
2001

Recent origin of Plasmodium falciparum from a single progenitor

S Volkman, A Barry, E Lyons, K Nielsen, S Thomas, M Choi, S Thakore, K Day, D Wirth, D Hartl

(2001), Vol. 293, pp. 482-484, Science, Cambridge, Mass., C1-1

journal article
2000

The 10q25 neocentromere and its inactive progenitor have identical primary nucleotide sequence: Further evidence for epigenetic modification

A Barry, M Bateman, E Howman, M Cancilla, K Tainton, D Irvine, R Saffery, K Choo

(2000), Vol. 10, pp. 832-838, Genome Research, Cold Spring Harbor, N.Y., C1-1

journal article
1999

Sequence analysis of an 80 kb human neocentromere

A Barry, E Howman, M Cancilla, R Saffery, K Choo

(1999), Vol. 8, pp. 217-227, Human Molecular Genetics, Oxford, Eng., C1-1

journal article
1998

Direct cloning of human 10q25 neocentromere DNA using transformation- associated recombination (TAR) in yeast

M Cancilla, K Tainton, A Barry, V Larionov, N Kouprina, M Resnick, D Sart, K Choo

(1998), Vol. 47, pp. 399-404, Genomics, Amsterdam, The Netherlands, C1-1

journal article
1997

A functional neo-centromere formed through activation of a latent human centromere and consisting of non-alpha-satellite DNA

D Sart, M Cancilla, E Earle, J Mao, R Saffery, K Tainton, P Kalitsis, J Martyn, A Barry, K Andy Choo

(1997), Vol. 16, pp. 144-153, Nature Genetics, London, Eng., C1-1

journal article
undefined

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

Ambroise Ahouidi, Mozam Ali, Jacob Almagro-Garcia, Alfred Amambua-Ngwa, Chanaki Amaratunga, Roberto Amato, Lucas Amenga-Etego, Ben Andagalu, Tim Anderson, Voahangy Andrianaranjaka, Tobias Apinjoh, Cristina Ariani, Elizabeth Ashley, Sarah Auburn, Gordon Awandare, Hampate Ba, Vito Baraka, Alyssa Barry, Philip Bejon, Gwladys Bertin, Maciej Boni, Steffen Borrmann, Teun Bousema, Oralee Branch, Peter Bull, George Busby, Thanat Chookajorn, Kesinee Chotivanich, Antoine Claessens, David Conway, Alister Craig, Umberto D'Alessandro, Souleymane Dama, Nicholas Day, Brigitte Denis, Mahamadou Diakite, Abdoulaye Djimdé, Christiane Dolecek, Arjen Dondorp, Chris Drakeley, Eleanor Drury, Patrick Duffy, Diego Echeverry, Thomas Egwang, Berhanu Erko, Rick Fairhurst, Abdul Faiz, Caterina Fanello, Mark Fukuda, Dionicia Gamboa, Anita Ghansah, Lemu Golassa, Sonia Goncalves, William Hamilton, G Harrison, Lee Hart, Christa Henrichs, Tran Hien, Catherine Hill, Abraham Hodgson, Christina Hubbart, Mallika Imwong, Deus Ishengoma, Scott Jackson, Chris Jacob, Ben Jeffery, Anna Jeffreys, Kimberly Johnson, Dushyanth Jyothi, Claire Kamaliddin, Edwin Kamau, Mihir Kekre, Krzysztof Kluczynski, Theerarat Kochakarn, Abibatou Konaté, Dominic Kwiatkowski, Myat Kyaw, Pharath Lim, Chanthap Lon, Kovana Loua, Oumou Maïga-Ascofaré, Cinzia Malangone, Magnus Manske, Jutta Marfurt, Kevin Marsh, Mayfong Mayxay, Alistair Miles, Olivo Miotto, Victor Mobegi, Olugbenga Mokuolu, Jacqui Montgomery, Ivo Mueller, Paul Newton, Thuy Nguyen, Thuy-Nhien Nguyen, Harald Noedl, François Nosten, Rintis Noviyanti, Alexis Nzila, Lynette Ochola-Oyier, Harold Ocholla, Abraham Oduro, Irene Omedo, Marie Onyamboko, Jean-Bosco Ouedraogo, Kolapo Oyebola, Richard Pearson, Norbert Peshu, Aung Phyo, Chris Plowe, Ric Price, Sasithon Pukrittayakamee, Milijaona Randrianarivelojosia, Julian Rayner, Pascal Ringwald, Kirk Rockett, Katherine Rowlands, Lastenia Ruiz, David Saunders, Alex Shayo, Peter Siba, Victoria Simpson, Jim Stalker, Xin-zhuan Su, Colin Sutherland, Shannon Takala-Harrison, Livingstone Tavul, Vandana Thathy, Antoinette Tshefu, Federica Verra, Joseph Vinetz, Thomas Wellems, Jason Wendler, Nicholas White, Ian Wright, William Yavo, Htut Ye

(), Vol. 6, pp. 42-42, Wellcome Open Research, C1

journal article

Funded Projects at Deakin

Australian Competitive Grants

Genetic determinants of antigenic escape in malaria parasites

A/Prof Alyssa Barry, Dr Shannon Harrison, Prof Takafumi Tsuboi

NHMRC Project Grant

  • 2022: $94,300
  • 2021: $190,941
  • 2020: $354,718
  • 2019: $186,703

Defining Host and Parasite Mechanisms that Drive Asymptomatic Malaria

A/Prof Alyssa Barry, A/Prof Leanne Robinson, Prof Takafumi Tsuboi, Prof James Kazura

NHMRC Project Grant

  • 2020: $369,808
  • 2019: $47,591

Other Public Sector Funding

Stronger Surveillance and Systems Support for Rapid Identification and Containment of Resurgent or Resistant Vector Borne Pathogens in Papua New Guinea (STRIVE PNG)

A/Prof Alyssa Barry

  • 2021: $57,145
  • 2020: $57,865

Long term physical and psychological consequences of Covid-19 infection. A Comparitive Observational Study in Regional Victoria.

Prof Eugene Athan, Dr Darcie Cooper, Prof Peter Vuillermin, Dr Daniel O'Brien, Prof John Stambas, Prof Alister Ward, Prof Michael Berk, Prof Julie Pasco, A/Prof Alyssa Barry, Prof Soren Alexandersen

  • 2021: $228,000

Industry and Other Funding

Associate Professor of Infection Systems Epidemiology.

A/Prof Alyssa Barry, Prof Alister Ward

  • 2022: $39,275
  • 2021: $172,492

ICEMR Mali: Multidisciplinary research for malaria control and prevention in West Africa

Prof Seydou Doumbia, A/Prof Alyssa Barry

  • 2021: $51,002
  • 2020: $33,348

Supervisions

No completed student supervisions to report