Prof David Ashley

STAFF PROFILE

Position

Visitor

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Publications

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2017

Condition-specific or generic preference-based measures in oncology? A comparison of the EORTC-8D and the EQ-5D-3L

P Lorgelly, B Doble, D Rowen, J Brazier, D Ashley, T Hayes, Cancer 2015 investigators

(2017), Vol. 26, pp. 1163-1176, Quality of life research, New York, N.Y., C1-1

journal

Methylation profiling of paediatric pilocytic astrocytoma reveals variants specifically associated with tumour location and predictive of recurrence

A Sexton-Oates, A Dodgshun, V Hovestadt, D Jones, D Ashley, M Sullivan, D MacGregor, R Saffery

(2017), pp. 1-36, Molecular oncology, Chichester, Eng., C1

journal

Comparison of outcomes for cancer patients discussed and not discussed at a multidisciplinary meeting

M Rogers, L Matheson, B Garrard, B Maher, S Cowdery, W Luo, M Reed, S Riches, G Pitson, D Ashley

(2017), Vol. 149, pp. 74-80, Public Health, London, Eng., C1

journal
2016

Retrospective analysis of cancer survival across South-Western Victoria in Australia

S Wong, L Matheson, K Morrissy, G Pitson, D Ashley, M Khasraw, P Lorgelly, M Henry

(2016), Vol. 24, pp. 79-84, Australian journal of rural health, London, Eng, C1

journal

Cancer diagnosed in the emergency department of a regional health service

M Rogers, L Matheson, B Garrard, V Mukaro, S Riches, M Sheridan, D Ashley, G Pitson

(2016), Vol. 24, pp. 409-414, Australian journal of rural health, London, Eng., C1

journal

Use of targeted therapy in cancer patients in the end-of-life period: results from an Australian centre

A Wann, D Ashley, M Khasraw

(2016), Vol. 24, pp. 3023-3028, Support care in cancer, Berlin, Germany, C1

journal

Low-dose histone deacetylase inhibitor treatment leads to tumor growth arrest and multi-lineage differentiation of malignant rhabdoid tumors

A Muscat, D Popovski, W Jayasekara, F Rossello, M Ferguson, K Marini, M Alamgeer, E Algar, P Downie, D Watkins, J Cain, D Ashley

(2016), Vol. 22, pp. 3560-3570, Clinical cancer research, Philadelphia, Penn., C1

journal

A discrete choice experiment to examine the preferences of patients with cancer and their willingness to pay for different types of health care appointments

S Wong, R Norman, T Dunning, D Ashley, M Khasraw, T Hayes, I Collins, P Lorgelly

(2016), Vol. 14, pp. 311-319, Journal of the national comprehensive cancer network, Cold Spring Harbor, N.Y., C1

journal

Toxicity prediction in cancer using multiple instance learning in a multi-task framework

C Li, S Gupta, S Rana, W Luo, S Venkatesh, D Ashley, Q Phung

(2016), Vol. 9651, pp. 152-164, Advances in knowledge discovery and data mining: 20th Pacific-Asia Conference, PAKDD 2016 Auckland, New Zealand, April 19-22, 2016 proceedings, part I, Berlin, Germany, B1

chapter

Multiple adverse effects prediction in longitudinal cancer treatment

C Li, S Gupta, S Rana, T Nguyen, S Venkatesh, D Ashley, P Livingston

(2016), pp. 3156-3161, ICPR 2016: Proceedings of the 23rd International Conference on Pattern Recognition, Cancun, Mexico, E1

conference
2015

A five-gene hedgehog signature developed as a patient preselection tool for hedgehog inhibitor therapy in medulloblastoma

Y Shou, D Robinson, D Amakye, K Rose, Y Cho, K Ligon, T Sharp, A Haider, R Bandaru, Y Ando, B Geoerger, F Doz, D Ashley, D Hargrave, M Casanova, H Tawbi, J Rodon, A Thomas, A Mita, T MacDonald, M Kieran

(2015), Vol. 21, pp. 585-593, Clinical cancer research, Philadelphia, PA, C1

journal

Oncology service initiatives and research in regional Australia

C Murphy, S Sabesan, C Steer, P Yates, A Booms, V Jones, A Simpson, K Clarke, R Eek, D Ashley, D Goldstein, C Packer, F Tuthill, A Boyce, C Underhill

(2015), Vol. 23, pp. 40-48, Australian journal of rural health, North Melbourne, Vic., C1

journal

Paediatric leukaemia DNA methylation profiling using MBD enrichment and SOLiD sequencing on archival bone marrow smears

N Wong, G Meredith, G Marnellos, M Dudas, M Parkinson-Bates, M Halemba, Z Chatterton, J Maksimovic, D Ashley, F Mechinaud, J Craig, R Saffery

(2015), Vol. 4, pp. 1-6, Gigascience, London, Eng., C1

journal

Accepting risk in the acceleration of drug development for rare cancers.

D Ashley, D Thomas, L Gore, R Carter, J Zalcberg, R Otmar, J Savulescu

(2015), Vol. 16, pp. e190-e194, Lancet Oncology, England, C1

journal

Unmet needs and depression among carers of people newly diagnosed with cancer

L Heckel, K Fennell, J Reynolds, R Osborne, J Chirgwin, M Botti, D Ashley, P Livingston

(2015), Vol. 51, pp. 2049-2057, European Journal of Cancer, Amsterdam, The Netherlands, C1

journal

Implementing novel models of posttreatment care for cancer survivors: Enablers, challenges and recommendations.

M Jefford, N Kinnane, P Howell, L Nolte, S Galetakis, G Bruce Mann, L Naccarella, J Lai-Kwon, K Simons, S Avery, K Thompson, D Ashley, M Haskett, E Davies, K Whitfield

(2015), Vol. 11, pp. 319-327, Asia Pacific journal of clinical oncology, London, Eng, C1

journal

Cancer 2015: a longitudinal whole-of-system study of genomic cancer medicine

D Thomas, S Fox, P Lorgelly, D Ashley, G Richardson, L Lipton, J Parisot, M Lucas, J McNeil, Michael Wright, for the Cancer 2015 Investigators

(2015), Vol. 20, pp. 1429-1432, Drug discovery today, Amsterdam, The Netherlands, C1

journal

"Cancer 2015": a prospective, population-based cancer cohort-phase 1: feasibility of genomics-guided precision medicine in the clinic

J Parisot, H Thorne, A Fellowes, K Doig, M Lucas, J McNeil, B Doble, A Dobrovic, T John, P James, L Lipton, D Ashley, T Hayes, P McMurrick, G Richardson, P Lorgelly, S Fox, D Thomas

(2015), Vol. 5, pp. 354-369, Journal of personalized medicine, Basel, Switzerland, C1-1

journal
2014

Efficacy and cost-effectiveness of an outcall program to reduce carer burden and depression among carers of cancer patients (PROTECT) : rationale and design of a randomized controlled trial

P Livingston, R Osborne, M Botti, C Mihalopoulos, S McGuigan, L Heckel, K Gunn, J Chirgwin, D Ashley, M Williams

(2014), Vol. 14, pp. 1-8, BMC health services research, London, England, C1

journal

Validation of DNA methylation biomarkers for diagnosis of acute lymphoblastic leukemia

Z Chatterton, D Burke, K Emslie, J Craig, J Ng, D Ashley, F Mechinaud, R Saffery, N Wong

(2014), Vol. 60, pp. 995-1003, Clinical chemistry, Chicago, IL, C1

journal

Machine-learning prediction of cancer survival: a retrospective study using electronic administrative records and a cancer registry

S Gupta, T Tran, W Luo, D Phung, R Kennedy, A Broad, D Campbell, D Kipp, M Singh, M Khasraw, L Matheson, D Ashley, S Venkatesh

(2014), Vol. 4, pp. 1-7, BMJ open, London, England, C1

journal

Epigenetic deregulation in pediatric acute lymphoblastic leukemia

Z Chatterton, L Morenos, F Mechinaud, D Ashley, J Craig, A Sexton-Oates, M Halemba, M Parkinson-Bates, J Ng, D Morrison, W Carroll, R Saffery, N Wong

(2014), Vol. 9, pp. 459-467, Epigenetics, New York, NY, C1

journal

Outpatient versus inpatient IV antibiotic management for pediatric oncology patients with low risk febrile neutropenia: a randomised trial

L Orme, F Babl, C Barnes, P Barnett, S Donath, D Ashley

(2014), Vol. 61, pp. 1427-1433, Pediatric blood and cancer, Hoboken, NJ, C1

journal

Radiotherapy in the Barwon South Western Region: a rural perspective

M Henry, P Jones, K Morrissy, L Matheson, G Pitson, P Healy, M Coory, R Lynch, A Chapman, D Ashley

(2014), Vol. 58, pp. 612-617, Journal of medical imaging and radiation oncology, Richmond, Vic, C1

journal

A protocol for a discrete choice experiment: understanding preferences of patients with cancer towards their cancer care across metropolitan and rural regions in Australia

S Wong, R Norman, T Dunning, D Ashley, P Lorgelly

(2014), Vol. 4, pp. 1-9, BMJ Open, London, England, C1

journal

Characteristics of cancer diagnoses and staging in South Western Victoria: a rural perspective

P Banks, L Matheson, K Morrissy, I Olesen, G Pitson, A Chapman, D Ashley, M Henry

(2014), Vol. 22, pp. 257-263, Australian Journal of Rural Health, Melbourne, Vic., C1

journal
2013

A phase II single-arm study of irinotecan in combination with temozolomide (TEMIRI) in children with newly diagnosed high grade glioma: a joint ITCC and SIOPE-brain tumour study

D Hargrave, B Geoerger, D Frappaz, T Pietsch, L Gesner, L Cisar, A Breazna, A Dorman, O Cruz-Martinez, J Fuster, X Rialland, C Icher, P Leblond, D Ashley, G Perilongo, M Elliott, M English, N Clausen, J Grill

(2013), Vol. 113, pp. 127-134, Journal of neuro-oncology, New York, N. Y., C1

journal

Sustained low-dose treatment with the histone deacetylase inhibitor LBH589 induces terminal differentation of osteosarcoma cells

J Cain, A McCaw, W Jayasekara, F Rossello, K Marini, A Irving, M Kansara, D Thomas, D Ashley, D Watkins

(2013), pp. 1-11, Sarcoma, New York, N. Y., C1

journal

New drugs for children and adolescents with cancer: the need for novel development pathways

G Vassal, C Zwaan, D Ashley, D Le, D Hargrave, P Blanc, P Adamson

(2013), Vol. 14, Lancet oncology, London, England, C1

journal

Emerging pharmacotherapy for cancer patients with cognitive dysfunction

J Davis, F Ahlberg, M Berk, D Ashley, M Khasraw

(2013), Vol. 13, BMC neurology, London, England, C1

journal

The oncogenic properties of EWS/WT1 of desmoplastic small round cell tumors are unmasked by loss of p53 in murine embryonic fibroblasts

P Bandopadhayay, A Jabbour, C Riffkin, M Salmanidis, L Gordon, D Popovski, L Rigby, D Ashley, D Watkins, D Thomas, E Algar, P Ekert

(2013), Vol. 13, pp. 1-14, BMC cancer, London, Eng., C1-1

journal

Case report of interstitial nephritis induced by bevacizumab therapy for glioblastoma multiforme

A Lomax, P Hill, D Ashley

(2013), Vol. 19, pp. 365-368, Journal of oncology pharmacy practice, London, Eng., C1-1

journal
2012

Using lithium as a neuroprotective agent in patients with cancer

M Khasraw, D Ashley, G Wheeler, M Berk

(2012), Vol. 10, pp. 1-7, BMC Medicine, London, England, C1

journal

Feasibility of neurobehavioral screening following diagnosis of pediatric cancer

L Pejnovic, C De Luca, E Gentle, K Anson, D Ashley, V Anderson, M McCarthy

(2012), Vol. 59, pp. 295-300, Pediatric blood and cancer, Hoboken, N. J., C1-1

journal

Methods for the analysis of histone H3 and H4 acetylation in blood

L Rigby, A Muscat, D Ashley, E Algar

(2012), Vol. 7, pp. 875-882, Epigenetics, Georgetown, Tex., C1-1

journal

A distinct DNA methylation signature defines pediatric pre-B cell acute lymphoblastic leukemia

N Wong, D Ashley, Z Chatterton, M Parkinson-Bates, H Ng, M Halemba, A Kowalczyk, J Bedo, Q Wang, K Bell, E Algar, J Craig, R Saffery

(2012), Vol. 7, pp. 535-541, Epigenetics, Georgetown, Tex., C1-1

journal

Evaluation of microRNA expression in patient bone marrow aspirate slides

L Morenos, R Saffery, F Mechinaud, D Ashley, N Elwood, J Craig, N Wong

(2012), Vol. 7, pp. 1-9, PLoS One, San Francisco, Calif., C1-1

journal

Induction chemotherapy and conformal radiation therapy for very young children with nonmetastatic medulloblastoma: children's oncology group study P9934

D Ashley, T Merchant, D Strother, T Zhou, P Duffner, P Burger, D Miller, N Lyon, M Bonner, M Msall, A Buxton, R Geyer, L Kun, L Coleman, I Pollack

(2012), Vol. 30, pp. 3181-3186, Journal of clinical oncology, Alexandria, Va., C1-1

journal

Enhanced lithium-induced brain recovery following cranial irradiation is not impeded by inflammation

J Malaterre, C McPherson, D Denoyer, E Lai, J Hagekyriakou, S Lightowler, K Shudo, M Ernst, D Ashley, J Short, G Wheeler, R Ramsay

(2012), Vol. 1, pp. 469-479, Stem cells translational medicine, Durham, N. C., C1-1

journal

Genome-wide DNA methylation in childhood cancer

N Wong, D Ashley

(2012), pp. 338-346, Epigenomics: from chromatin biology to therapeutics, New York, N. Y., B1-1

chapter

Acute pain associated with oxaliplatin infusion: case report and literature review

T Clay, D Ashley

(2012), Vol. 18, pp. 421-424, Journal of oncology pharmacy practice, London, Eng., C1-1

journal

Predictors of acute and posttraumatic stress symptoms in parents following their child's cancer diagnosis

M McCarthy, D Ashley, K Lee, V Anderson

(2012), Vol. 25, pp. 558-566, Journal of traumatic stress, London, Eng., C1-1

journal
2011

ANZCCSG BabyBrain99; intensified systemic chemotherapy, second look surgery and involved field radiation in young children with central nervous system malignancy

P Bandopadhayay, T Hassall, J Rosenfeld, G Wheeler, P Downie, M Kirby, R Cohn, M Sullivan, D Ashley

(2011), Vol. 56, pp. 1055-1061, Pediatric blood and cancer, Hoboken, N.J., C1-1

journal

High expression of BMP pathway genes distinguishes a subset of atypical teratoid/rhabdoid tumors associated with shorter survival

D Birks, A Donson, P Patel, C Dunham, A Muscat, E Algar, D Ashley, B Kleinschmidt-Demasters, R Vibhakar, M Handler, N Foreman

(2011), Vol. 13, pp. 1296-1307, Neuro-oncology, Oxford, Eng., C1-1

journal
2010

DNA methylation and miRNA expression profiling in childhood B-cell acute lymphoblastic leukemia

Z Chatterton, L Morenos, R Saffery, J Craig, D Ashley, N Wong

(2010), Vol. 2, pp. 697-708, Epigenomics, London, England, C1-1

journal
2009

Imprinted CDKN1C is a tumor suppressor in rhabdoid tumor and activated by restoration of SMARCB1 and histone deacetylase inhibitors

E Algar, A Muscat, V Dagar, C Rickert, C Chow, J Biegel, P Ekert, R Saffery, J Craig, R Johnstone, D Ashley

(2009), Vol. 4, pp. 1-13, PLoS one, San Francisco, Calif., C1-1

journal

Measuring psychosocial risk in families caring for a child with cancer : the psychosocial assessment tool (PAT2.0)

M McCarthy, N Clarke, A Vance, D Ashley, J Heath, V Anderson

(2009), Vol. 53, pp. 78-83, Pediatric blood and cancer, Hoboken, N. J., C1-1

journal

Approaches, challenges, and experience in assessing free nicotine

D Ashley, J Pankow, A Tavakoli, C Watson

(2009), Vol. 192, pp. 437-456, Handbook of experimental pharmacology, New York, N.Y., C1-1

journal

A pilot study of risk-adapted radiotherapy and chemotherapy in patients with supratentorial PNET

M Chintagumpala, T Hassall, S Palmer, D Ashley, D Wallace, K Kasow, T Merchant, M Krasin, R Dauser, F Boop, R Krance, S Woo, R Cheuk, C Lau, R Gilbertson, A Gajjar

(2009), Vol. 11, pp. 33-40, Neuro-oncology, Cary, N.C., C1-1

journal

Gender differences in the psychosocial experience of parents of children with cancer : a review of the literature

N Clarke, M McCarthy, P Downie, D Ashley, V Anderson

(2009), Vol. 18, pp. 907-915, Psycho-oncology, Chichester, England, C1-1

journal

Survivors of childhood cancer : an Australian audit of vaccination status after treatment

N Crawford, J Heath, D Ashley, P Downie, J Buttery

(2009), Vol. 54, pp. 128-133, Pediatric blood and cancer, Hoboken, N. J., C1-1

journal

Rapid detection of SMARCB1 sequence variation using high resolution melting

V Dagar, C Chow, D Ashley, E Algar

(2009), Vol. 9, pp. 1-9, BMC cancer, London, England, C1-1

journal

Radiotherapy management of patients diagnosed with glioma in Victoria (1998-2000) : a retrospective cohort study

M Dally, M Rosenthal, K Drummond, M Murphy, L Cher, D Ashley, V Thursfield, G Giles

(2009), Vol. 53, pp. 318-324, Journal of medical imaging and radiation oncology, Melbourne, Vic., C1-1

journal

The role of social support in families coping with childhood brain tumor

A Jackson, K Enderby, M O'Toole, S Thomas, D Ashley, J Rosenfeld, E Simos, N Tokatlian, R Gedye

(2009), Vol. 27, pp. 1-26, Journal of psychosocial oncology, London, England, C1-1

journal
2008

Costimulation molecule expression and subset distribution of blood dendritic cells in normal children and newly diagnosed pediatric leukemia and lymphoma patients

D Caruso, S Fraser, K Hardy, G Amor, J Helmich, D Ashley

(2008), Vol. 36, pp. 1691-1703, Experimental Hematology, Philadelphia, Pa., C1-1

journal

In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs

D Ashley, C Riffkin, M Lovric, T Mikeska, A Dobrovic, J Maxwell, H Friedman, K Drummond, A Kaye, H Gan, T Johns, C Hawkins

(2008), Vol. 99, pp. 294-304, British Journal of Cancer, London, Eng., C1-1

journal

Amifostine protects against cisplatin-induced ototoxicity in children with average-risk medulloblastoma

M Fouladi, M Chintagumpala, D Ashley, S Kellie, S Gururangan, T Hassall, L Gronewold, C Stewart, D Wallace, A Broniscer, G Hale, K Kasow, T Merchant, B Morris, M Krasin, L Kun, J Boyett, A Gajjar

(2008), Vol. 26, pp. 3749-3755, Journal of Clinical Oncology, Alexandria, Va., C1-1

journal

Brain stem gliomas: patterns of care in Victoria from 1998-2000

M Rosenthal, D Ashley, K Drummond, M Dally, M Murphy, L Cher, V Thursfield, G Giles

(2008), Vol. 15, pp. 237-240, Journal of Clinical Neuroscience, Amsterdam, The Netherlands, C1-1

journal

Rhabdoid tumour: a malignancy of early childhood with variable primary site, histology and clinical behaviour

X Wu, V Dagar, E Algar, A Muscat, P Bandopadhayay, D Ashley, C Wo Chow

(2008), Vol. 40, pp. 664-670, Pathology, London, Eng., C1-1

journal

The use of chemotherapy in patients with gliomas: patterns of care in Victoria from 1998-2000

L Cher, M Rosenthal, K Drummond, M Dally, M Murphy, D Ashley, V Thursfield, G Giles

(2008), Vol. 15, pp. 398-401, Journal of Clinical Neuroscience, London, Eng., C1-1

journal
2007

Multiple factors contribute to neuropsychological outcome in children with posterior fossa tumors

R Stargatt, J Rosenfeld, W Maixner, D Ashley

(2007), Vol. 32, pp. 729-748, Developmental Neuropsychology, Philadelphia, Pa., C1-1

journal

Temozolomide in pediatric low-grade glioma

S Khaw, L Coleman, P Downie, J Heath, D Ashley

(2007), Vol. 49, pp. 808-811, Pediatric blood & cancer, London, Eng., C1-1

journal

Pediatric brain tumor patients: their parents' perceptions of the hospital experience

A Jackson, H Stewart, M O'Toole, N Tokatlian, K Enderby, J Miller, D Ashley

(2007), Vol. 24, pp. 95-105, Journal of Pediatric Oncology Nursing, Thousand Oaks, Calif., C1-1

journal

Polymorphisms in genes encoding drug metabolizing enzymes and their influence on the outcome of children with neuroblastoma

L Ashton, J Murray, M Haber, G Marshall, D Ashley, M Norris

(2007), Vol. 17, pp. 709-717, Pharmacogenetics and genomics, Philadelphia, Pa., C1-1

journal
2006

Intelligence and adaptive function in children diagnosed with brain tumour during infancy

R Stargatt, J Rosenfeld, V Anderson, T Hassall, W Maixner, D Ashley

(2006), Vol. 80, pp. 295-303, Journal of neuro-oncology, Berlin, Germany, C1-1

journal

Caspase-8 levels correlate with the expression of signal transducer and activator of transcription 1 in high-grade but not lower grade neuroblastoma

A Muscat, C Hawkins, D Ashley

(2006), Vol. 107, pp. 824-831, Cancer, Chichester, Eng., C1-1

journal

Human Bcl-2 cannot directly inhibit the Caenorhabditis elegans Apaf-1 homologue CED-4, but can interact with EGL-1

A Jabbour, M Puryer, J Yu, T Lithgow, C Riffkin, D Ashley, D Vaux, P Ekert, C Hawkins

(2006), Vol. 119, pp. 2572-2582, Journal of cell science, Cambridge, Eng., C1-1

journal

Phase II study of two-weekly temozolomide in patients with high-grade gliomas

S Wong, M Rosenthal, A Dowling, R Jennens, A-M Woods, D Ashley, L Cher

(2006), Vol. 13, pp. 18-22, Journal of clinical neuroscience, London, Eng., C1-1

journal

Adolescent and young adult cancer: a revolution in evolution?

D Thomas, J Seymour, T O'Brien, S Sawyer, D Ashley

(2006), Vol. 36, pp. 302-307, Internal medicine journal, Chichester, Eng., C1-1

journal

Management of glioma in Victoria (1998-2000): retrospective cohort study

M Rosenthal, K Drummond, M Dally, M Murphy, L Cher, D Ashley, V Thursfield, G Giles

(2006), Vol. 184, pp. 270-273, Medical journal of Australia, Sydney, N.S.W., C1-1

journal

Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial

A Gajjar, M Chintagumpala, D Ashley, S Kellie, L Kun, T Merchant, S Woo, G Wheeler, V Ahern, M Krasin, M Fouladi, A Broniscer, R Krance, G Hale, C Stewart, R Dauser, R Sanford, C Fuller, C Lau, J Boyett, D Wallace, R Gilbertson

(2006), Vol. 7, pp. 813-820, Lancet oncology, London, Eng., C1-1

journal

Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations

M Thompson, C Fuller, T Hogg, J Dalton, D Finkelstein, C Lau, M Chintagumpala, A Adesina, D Ashley, S Kellie, M Taylor, T Curran, A Gajjar, R Gilbertson

(2006), Vol. 24, pp. 1924-1931, Journal of clinical oncology, Alexandria, Va., C1-1

journal
2005

Results of a Phase I study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children with Stage 4 neuroblastoma

D Caruso, L Orme, G Amor, A Neale, F Radcliff, P Downie, M Tang, D Ashley

(2005), Vol. 103, pp. 1280-1291, Cancer, Hoboken, N.J., C1-1

journal

Caspase 8 is absent or low in many ex vivo gliomas

D Ashley, C Riffkin, A Muscat, M Knight, A Kaye, U Novak, C Hawkins

(2005), Vol. 104, pp. 1487-1496, Cancer, Hoboken, N.J., C1-1

journal

Neurocognitive consequences of risk-adapted therapy for childhood medulloblastoma

R Mulhern, S Palmer, T Merchant, D Wallace, M Kocak, P Brouwers, K Krull, M Chintagumpala, R Stargatt, D Ashley, V Tyc, L Kun, J Boyett, A Gajjar

(2005), Vol. 23, pp. 5511-5519, Journal of clinical oncology, Alexandria, Va., C1-1

journal
2004

Cancer in adolescents and young adults: treatment and outcome in Victoria

A Mitchell, D Scarcella, G Rigutto, V Thursfield, G Giles, M Sexton, D Ashley

(2004), Vol. 180, pp. 59-62, Medical journal of Australia, Sydney, N.S.W., C1-1

journal

Urinary diversion in children with pelvic tumors

D Meir, M Inoue, U Gur, P Livne, Y Yaniv, K Tiedeman, D Ashley, J Hutson

(2004), Vol. 39, pp. 1787-1790, Journal of pediatric surgery, Amsterdam, The Netherlands, C1-1

journal

The Caenorhabditis elegans CED-9 protein does not directly inhibit the caspase CED-3, in vitro nor in yeast

A Jabbour, P-K Ho, M Puryer, D Ashley, P Ekert, C Hawkins

(2004), Vol. 11, pp. 1309-1316, Cell death and differentiation, London, Eng., C1-1

journal

Clinical, histopathologic, and molecular markers of prognosis: toward a new disease risk stratification system for medulloblastoma

A Gajjar, R Hernan, M Kocak, C Fuller, Y Lee, P McKinnon, D Wallace, C Lau, M Chintagumpala, D Ashley, S Kellie, L Kun, R Gilbertson

(2004), Vol. 22, pp. 984-993, Journal of clinical oncology, Alexandria, Va., C1-1

journal

Phase 2 study of temozolomide and Caelyx in patients with recurrent glioblastoma multiforme

S Chua, M Rosenthal, S Wong, D Ashley, A-M Woods, A Dowling, L Cher

(2004), Vol. 6, pp. 38-43, Neuro-oncology, Oxford, Eng., C1-1

journal

Results of a phase 1 study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children and young adults with brain cancer

D Caruso, L Orme, A Neale, F Radcliff, G Amor, W Maixner, P Downie, T Hassall, M Tang, D Ashley

(2004), Vol. 6, pp. 236-246, Neuro-oncology, Oxford, Eng., C1-1

journal

Caspase-8 levels affect necessity for mitochondrial amplification in death ligand-induced glioma cell apoptosis

M Knight, C Riffkin, P Ekert, D Ashley, C Hawkins

(2004), Vol. 39, pp. 173-182, Molecular carcinogenesis, New York, N.Y., C1-1

journal

White matter lesions detected by magnetic resonance imaging after radiotherapy and high-dose chemotherapy in children with medulloblastoma or primitive neuroectodermal tumor

M Fouladi, M Chintagumpala, F Laningham, D Ashley, S Kellie, J Langston, C McCluggage, S Woo, M Kocak, K Krull, L Kun, R Mulhern, A Gajjar

(2004), Vol. 22, pp. 4551-4560, Journal of clinical oncology, Alexandria, Va., C1-1

journal

Results of a phase II upfront window of pharmacokinetically guided topotecan in high-risk medulloblastoma and supratentorial primitive neuroectodermal tumor

C Stewart, L Iacono, M Chintagumpala, S Kellie, D Ashley, W Zamboni, M Kirstein, M Fouladi, L Seele, D Wallace, P Houghton, A Gajjar

(2004), Vol. 22, pp. 3357-3365, Journal of clinical oncology, Alexandria, Va., C1-1

journal
2003

Health-related quality of life of children with acute lymphoblastic leukaemia: comparisons and correlations between parent and clinician reports

E Waters, M Wake, K Hesketh, D Ashley, E Smibert

(2003), Vol. 103, pp. 514-518, International journal of cancer, New York, N.Y., C1-1

journal

General anaesthesia or conscious sedation for painful procedures in childhood cancer: the family's perspective

C Crock, C Olsson, R Phillips, G Chalkiadis, S Sawyer, D Ashley, S Camilleri, J Carlin, P Monagle

(2003), Vol. 88, pp. 253-257, Archives of disease in childhood, London, England, C1-1

journal

Megestrol acetate in pediatric oncology patients may lead to severe, symptomatic adrenal suppression

L Orme, J Bond, M Humphrey, M Zacharin, P Downie, K Jamsen, S Mitchell, J Robinson, N Grapsas, D Ashley

(2003), Vol. 98, pp. 397-405, Cancer, Chichester, Eng., C1-1

journal
2002

Mobilization of dendritic cells in cancer patients treated with granulocyte colony-stimulating factor and chemotherapy

F Radcliff, D Caruso, C Koina, M Riordan, A Roberts, M Tang, C Baum, S Woulfe, D Ashley

(2002), Vol. 119, pp. 204-211, British journal of haematology, Chichester, Eng., C1-1

journal

The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis

A Jabbour, P Ekert, E Coulson, M Knight, D Ashley, C Hawkins

(2002), Vol. 9, pp. 1311-1320, Cell death & differentiation, London, England, C1-1

journal

Grants

Australian Competitive Grants

Genome-wide epigenetic analysis of Childhood Acute Lymphoblastic Leukaemia

Dr Jeff Craig, Dr Nick Wong, Prof David Ashley

NHMRC Project Grant

  • 2011: $120,000

Reducing Carer Burden and Depression among Caregivers.

Prof Trish Livingston, Prof Richard Osborne, Prof Mari Botti, Jacqui Chirgwin, Dr John Reynolds, Prof David Ashley

NHMRC Project Grant

  • 2015: $188,433
  • 2014: $186,522
  • 2013: $182,390

Epigenetic predictors of outcome in malignant glioma

Prof David Ashley, A/Prof Elizabeth Algar, Dr Nick Wong, Dr Mark Rosenthal, Dr Kathryn Field, A/Prof Katharine Drummond

NHMRC Project Grant

  • 2015: $177,309
  • 2014: $290,258
  • 2013: $230,152

M-Health: Efficacy and Cost-effectiveness of a smartphone App to reduce unmet needs and distress in people with cancer (ACE): a randomized controlled trial

Prof Trish Livingston, Prof David Ashley, Prof Suzanne Chambers, A/Prof Victoria White, Jacqui Chirgwin, A/Prof Meinir Krishnasamy, Dr Cathy Mihalopoulos, Prof Mari Botti, A/Prof Liliana Orellana

NHMRC - Partnership Project

  • 2017: $101,274
  • 2016: $117,321

A Phase II Study of continuous, low-dose LBH 589 (Panobinostat) in Patients with Refractory Solid Tumors, including CNS tumors

Prof David Ashley, Dr Jayesh Desai, Dr Jason Cain, Dr Nicholas Gottardo, Dr Paul Wood

NHMRC Project Grant

  • 2017: $176,613

Other Public Sector Funding

Using Lithium as a neuroprotectant in patients undergoing prophylactic cranial irradiation for small cell lung cancer - A feasibility study.

Prof David Ashley, Dr Greg Wheeler, Dr Mustafa Khasraw, Prof Michael Berk, A/Prof Robert Ramsay

  • 2012: $80,000

The Victorian Lung Cancer Initiative

Prof Neil Watkins, Dr Tracy Brown, Dr Jeremy Millar, Dr Benjamin Solomon, A/Prof Paul Mitchell, Dr Gavin Wright, A/Prof Louis Irving, Prof David Ashley

  • 2013: $106,041
  • 2011: $70,694

Cancer 2015: The Victorian Cancer Genome Cohort

Prof Joseph Sambrook, A/Prof Stephen Fox, Dr Thomas John, Dr Paula Lorgelly, A/Prof lara Lipton, Prof John McNeil, A/Prof Melissa Southey, A/Prof David Thomas, Prof Neil Watkins, Prof Paul Waring, Prof David Ashley

  • 2014: $52,200
  • 2013: $26,100
  • 2012: $180,000

Patients' preferences for cancer treatment: a discrete choice experiment to understand the role of choice in explaining regional disparities

Prof David Ashley, Dr Shu Fen Wong

  • 2013: $17,500
  • 2012: $17,500

Patients' preferences for cancer treatment: a discrete choice experiment to understand the role of choice in explaining regional disparities

Prof David Ashley, Dr Shu Fen Wong

  • 2015: $24,263
  • 2014: $40,057

M-Health: Efficacy and Cost-effectiveness of a smartphone App to reduce unmet needs and distress in people with cancer (ACE): a randomized controlled trial

Prof Trish Livingston, Prof David Ashley, Prof Suzanne Chambers, A/Prof Victoria White, Jacqui Chirgwin, A/Prof Meinir Krishnasamy, Dr Cathy Mihalopoulos, Prof Mari Botti, A/Prof Liliana Orellana

  • 2017: $20,000
  • 2016: $25,000

Victorian Epigenetics Group (VEG): Histone deacetylase inhibitors as differentiation therapy for paediatric solid tumours

Prof Miles Prince, Prof David Ashley

  • 2016: $38,000
  • 2015: $105,000

Identifying predictors of functioning in people with advanced cancer and their caregivers in rural and regional communities: A prospective, longitudinal study.

Dr Anna Ugalde, Prof Trish Livingston, Prof David Ashley, A/Prof Meinir Krishnasamy, Dr Anna Boltong, Dr Penelope Schofield, Prof Suzanne Chambers, Prof Sanchia Aranda

  • 2015: $100,000

Cancer App Delivery Improvement (CANDID) Study

Prof David Ashley, Prof Trish Livingston, Ms Anne Woollett, A/Prof John Reynolds, Dr Barbara Lavelle

  • 2014: $27,272

Qubit Fluorometer 3.0

Prof David Ashley

  • 2014: $2,268

Cancer 2015: The Victorian Cancer Genome Cohort - Phase 2

A/Prof Stephen Fox, Prof David Ashley

  • 2016: $42,554
  • 2015: $68,086

Victorian Epigenetics Group (VEG): Integrating genomic and epigenomic predictive biomarkers in aza treated MDS

Prof Miles Prince, Prof David Ashley

  • 2017: $10,000
  • 2016: $41,500
  • 2015: $70,300

Whole exome sequencing and methylation profiling of Neuroendocrine cancers from patients on the NABNEC trial

Dr Mustafa Khasraw, Prof David Ashley

  • 2017: $30,000

Industry and Other Funding

Rotary BowelScan Scholarship

Prof David Ashley, Dr Shu Fen Wong

  • 2013: $17,500
  • 2012: $17,500

M-Health: Efficacy and Cost-effectiveness of a smartphone App to reduce unmet needs and distress in people with cancer (ACE): a randomized controlled trial

Prof Trish Livingston, Prof David Ashley, Prof Suzanne Chambers, A/Prof Victoria White, Jacqui Chirgwin, A/Prof Meinir Krishnasamy, Dr Cathy Mihalopoulos, Prof Mari Botti, A/Prof Liliana Orellana

  • 2017: $30,000
  • 2016: $15,000

Whole exome sequencing and methylation profiling of Neuroendocrine cancers from patients on the NABNEC trial

Dr Mustafa Khasraw, Prof David Ashley

  • 2017: $4,570
  • 2016: $4,124

Identifying the role of altered mitochondrial metabolism in malignant rhabdoid tumours and evaluating potential epigenetic therapies

Prof David Ashley, A/Prof Sean Mcgee, Dr Jason Cain

  • 2016: $23,000

Other Funding Sources

M-Health: Efficacy and Cost-effectiveness of a smartphone App to reduce unmet needs and distress in people with cancer (ACE): a randomized controlled trial

Prof Trish Livingston, Prof David Ashley, Prof Suzanne Chambers, A/Prof Victoria White, Jacqui Chirgwin, A/Prof Meinir Krishnasamy, Dr Cathy Mihalopoulos, Prof Mari Botti, A/Prof Liliana Orellana

  • 2017: $5,000

Supervisions

No completed student supervisions to report