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A/Prof. Fred Pfeffer

STAFF PROFILE

Position

Associate Professor of Chemistry

Faculty

Faculty of Sci Eng & Built Env

Department

School of Life & Env Sciences

Campus

Geelong Waurn Ponds Campus

Qualifications

Doctor of Philosophy, Deakin University, 2001
Bachelor of Science, Deakin University, 1996

Contact

fred.pfeffer@deakin.edu.au
+61 3 522 71439

Biography

Dr Pfeffer received his PhD from Deakin University in 2001.  He then spent a year lecturing at Trinity College Dublin (TCD) then a further 14 months at TCD as a postdoctoral research fellow working with Professor Thorfinnur Gunnlaugsson on the synthesis and evaluation of fluorescent anion sensors. 

Dr Pfeffer returned to Deakin in 2004 to the faculty of Science and Technology as a lecturer and was appointed senior Lecturer in 2009.  He continues to pursue research in the field of supramolecular anion recognition chemistry but has also developed several successful medicinal chemistry programs including the synthesis of new antibiotics, anticancer agents and also insulin sensitising antidiabetic agents.  At the core of these programs is the appreciation and understanding of how molecules interact and interconvert—fundamental topics in chemistry.

As at Aug 2015 he has >60 peer reviewed publications, over 2500 citations and a H-index of 21.

Read more on Fred's profile

Research interests

Supramolecular chemistry; in particular anion recognition and sensing using conformationally preorganised frameworks and metal assembled cages (collaboration with Prof Thorfinnur Gunnlaugsson from Trinity College Dublin-Ireland and also Prof Guido Clever from TU Dortmund - Germany)

Bioactive heterocycles as therapeutics and diagnostics (Collaboration with Dr Scott Stewart from UWA, Dr Sean McGee, Prof Ken Walder and Dr Guy Krippner from Verva)

Synthesis of new cationic amphiphilies as antimicrobial peptide mimics (collaboration with Prof Roger Nation and Dr Jian Li at Monash MIPS and also Prof Matthew Cooper and Dr Alysha Elliot from University of Queensland)

Recent grants include:

Discovery DP140100227 Novel Synthetic Receptors for Recognition and Transport of Biologically Important Anions

MRCF (Medical Research Commercialisation Fund) Rapid development of
new antidiabetic agents.

Linkage Infrastructure LE120100213 Advanced Fluorescence Characterisation Facility

Linkage LP100100087 Discovery and development of novel insulin sensitising compounds for the treatment of Type 2 diabetes.

Affiliations

RACI (Royal Australian Chemical Institute)

ACS (American Chemical Society)

RSC (Royal Society of Chemistry)

Teaching interests

Synthetic Organic and Medicinal Chemistry

Units taught

SLE155, SLE210, SLE214, SLE318, SLE313, SLEhons(chem)

Knowledge areas

Organic Chemistry

Supramolecular Chemistry

Medicinal Chemistry

Publications

Filter by

2023

Waste to high-value products: The performance and potential of carboxymethylcellulose hydrogels via the circular economy

Prabhpreet Kaur, Himadri Bohidar, David Nisbet, Frederick Pfeffer, Aaqil Rifai, Richard Williams, Ruchi Agrawal

(2023), Vol. 30, pp. 2713-2730, Cellulose, Berlin, Germany, C1

journal article

Hydrogels in Agriculture: Prospects and Challenges

P Kaur, R Agrawal, F Pfeffer, R Williams, H Bohidar

(2023), Vol. 31, pp. 1-18, Journal of Polymers and the Environment, Berlin, Germany, C1

journal article

A comparative assessment of biomass pretreatment methods for the sustainable industrial upscaling of rice straw into cellulose

P Kaur, H Bohidar, F Pfeffer, R Williams, R Agrawal

(2023), Vol. 30, pp. 4247-4261, Cellulose, Berlin, Germany, C1

journal article

A fluorescent and solvatochromic 1,8-naphthalimide probe for detection of lipid droplet trafficking and biogenesis

S Hickey, I Johnson, E Dallerba, M Hackett, M Massi, J Lazniewska, L Thurgood, F Pfeffer, D Brooks, T Ashton

(2023), Vol. 217, pp. 1-6, Dyes and Pigments, Amsterdam, The Netherlands, C1

journal article

Synthesis of 3,4-dihydroxy-1,8-naphthalimides with inbuilt catechol and crown ether functionalities

Elley Rudebeck, Trent Ashton, Adam Henwood, Thorfinnur Gunnlaugsson, Frederick Pfeffer

(2023), Vol. 21, pp. 5970-5976, Organic and Biomolecular Chemistry, Cambridge, Eng., C1

journal article
2022

Synthesis of 2-[2-(tert-butoxycarbonyl)-3-(acyl)guanidino]ethylamine salts for convergent introduction of acyl guanidines

G Boer, S Hickey, A Elliott, F Pfeffer

(2022), Vol. 46, pp. 8131-8137, New Journal of Chemistry, London, Eng., C1

journal article

A 3,4-dimethoxy-1,8-naphthalimide for lipid droplet imaging in live and fixed cells

I Johnson, E Rudebeck, M Sweetman, A Sorvina, T Ashton, F Pfeffer, D Brooks, S Hickey

(2022), Vol. 365, pp. 1-7, Sensors and Actuators B: Chemical, Amsterdam, The Netherlands, C1

journal article

Norbornane-based antibacterial agents: Benzyl and benzoyl substituted guanidines

Gareth Boer, Shane Hickey, Alysha Elliott, Frederick Pfeffer

(2022), Vol. 6, pp. 1-12, European Journal of Medicinal Chemistry Reports, Amsterdam, The Netherlands, C1

journal article
2021

A rhodamine-naphthalimide-benzamide trichromophoric system with solid-state and multiple solvent dependent aggregate emissive properties

H Sharma, K Hearn, A Ranieri, C Caporale, M Massi, F Pfeffer

(2021), Vol. 5, pp. 5024-5032, Materials Chemistry Frontiers, C1

journal article

Direct amidation to access 3-amido-1,8-naphthalimides including fluorescent scriptaid analogues as hdac inhibitors

K Hearn, T Ashton, R Acharya, Z Feng, N Gueven, F Pfeffer

(2021), Vol. 10, Cells, Switzerland, C1

journal article

Direct Observation of Amide Bond Formation in a Plasmonic Nanocavity Triggered by Single Nanoparticle Collisions

Na Kong, Jing Guo, Shuai Chang, Jie Pan, Jianmei Wang, Jianghao Zhou, Jing Liu, Hong Zhou, Frederick Pfeffer, Jingquan Liu, Colin Barrow, Jin He, Wenrong Yang

(2021), Vol. 143, pp. 9781-9790, Journal of the American Chemical Society, Washington, D.C., C1

journal article

Intracellular fluorescence competition assay for inhibitor engagement of histone deacetylase

S Padilla-Coley, E Rudebeck, B Smith, F Pfeffer

(2021), Vol. 47, Bioorganic and Medicinal Chemistry Letters, England, C1

journal article

Treatment technologies to mitigate the harmful effects of recalcitrant fluoroquinolone antibiotics on the environ- ment and human health

P Mathur, D Sanyal, D Callahan, X Conlan, F Pfeffer

(2021), Vol. 291, Environmental Pollution, England, C1

journal article

Comparing the anion binding of 4-amido- with 4-amino-1,8-naphthalimides

Jacob Filiti, Kyle Hearn, Elley Rudebeck, Thien Huynh, Pham-Tran Nguyen-Nguyen, Frederick Pfeffer

(2021), Vol. 19, pp. 9260-9265, Organic and Biomolecular Chemistry, Cambridge, Eng., C1

journal article
2020

A fluorescent naphthalimide NADH mimic for continuous and reversible sensing of cellular redox state

Hemant Sharma, Nian Tan, Natalie Trinh, Jia Yeo, Elizabeth New, Frederick Pfeffer

(2020), Vol. 56, pp. 2240-2243, Chemical communications, Cambridge, Eng., C1

journal article

The identification of synthetic cannabinoids surface coated on herbal substrates using solid-state nuclear magnetic resonance spectroscopy

N Burns, A Theakstone, H Zhu, L O'Dell, J Pearson, T Ashton, F Pfeffer, X Conlan

(2020), Vol. 1104, pp. 105-109, Analytica Chimica Acta, Amsterdam, The Netherlands, C1

journal article

Mixed alkoxy/hydroxy 1,8-naphthalimides: expanded fluorescence colour palette and: In vitro bioactivity

E Rudebeck, R Cox, T Bell, R Acharya, Z Feng, N Gueven, T Ashton, F Pfeffer

(2020), Vol. 56, pp. 6866-6869, Chemical Communications, England, C1

journal article

Scaffold diversity for enhanced activity of glycosylated inhibitors of fungal adhesion

H Martin, T Somers, M Dwyer, R Robson, F Pfeffer, R Bjornsson, T Krämer, K Kavanagh, T Velasco-Torrijos

(2020), Vol. 11, pp. 1386-1401, RSC Medicinal Chemistry, England, C1

journal article
2019

Highly fluorescent and HDAC6 selective scriptaid analogues

Cassandra Fleming, Anthony Natoli, Jeannette Schreuders, Mark Devlin, Prusothman Yoganantharajah, Yann Gibert, Kathryn Leslie, Elizabeth New, Trent Ashton, Frederick Pfeffer

(2019), Vol. 162, pp. 321-333, European journal of medicinal chemistry, Amsterdam, The Netherlands, C1

journal article

Use of Mg-Al Nanoclay as an Efficient Vehicle for the Delivery of the Herbicide 2,4-Dichlorophenoxyacetic Acid

P Nadiminti, H Sharma, S Kada, F Pfeffer, L O'Dell, D Cahill

(2019), Vol. 7, pp. 10962-10970, ACS Sustainable Chemistry and Engineering, C1

journal article

A rhodamine-nitronaphthalimide Hg(II) complex for the simultaneous detection of oxidised and reduced glutathione

H Sharma, J White, J Lin, E New, F Pfeffer

(2019), Vol. 300, Sensors and Actuators, B: Chemical, C1

journal article

To cooperate or not: the role of central functionality in bisthiourea [6]polynorbornane hosts

R Robson, B Hay, F Pfeffer

(2019), Vol. 2019, pp. 6720-6727, European journal of organic chemistry, Chichester, Eng., C1

journal article
2018

Extraction, identification and detection of synthetic cannabinoids found pre-ban in herbal products in Victoria, Australia

N Burns, T Ashton, P Stevenson, J Pearson, I Fox, F Pfeffer, P Francis, Z Smith, N Barnett, L Chen, J White, X Conlan

(2018), Vol. 7, pp. 19-25, Forensic chemistry, Amsterdam, The Netherlands, C1

journal article

Norbornene chaotropic salts as low molecular mass ionic organogelators (LMIOGs)

J Engstrom, A Savyasachi, M Parhizkar, A Sutti, C Hawes, J White, T Gunnlaugsson, F Pfeffer

(2018), Vol. 9, pp. 5233-5241, Chemical Science, England, C1

journal article

Norbornane-based cationic antimicrobial peptidomimetics targeting the bacterial membrane

Shane Hickey, Trent Ashton, Gareth Boer, Christie Bader, Michael Thomas, Alysha Elliott, Carsten Schmuck, Heidi Yu, Jian Li, Roger Nation, Matthew Cooper, Sally Plush, Douglas Brooks, Frederick Pfeffer

(2018), Vol. 160, pp. 9-22, European journal of medicinal chemistry, Amsterdam, The Netherlands, C1

journal article
2017

Colorimetric semi-quantitative measurement of pyrophosphate by functionalised SPPS resin in biological media

B Long, F Pfeffer, C Barrow

(2017), Vol. 243, pp. 761-764, Sensors and actuators B: chemical, Amsterdam, The Netherlands, C1

journal article

Flexible "Arms" and Anion Recognition

R Robson, B Hay, F Pfeffer

(2017), Vol. 2, pp. 4605-4608, ChemistrySelect, C1

journal article

Modular synthesis of 4-aminocarbonyl substituted 1,8-naphthalimides and application in single molecule fluorescence detection

K Hearn, T Nalder, R Cox, H Maynard, T Bell, F Pfeffer, T Ashton

(2017), Vol. 53, pp. 12298-12301, Chemical Communications, England, C1

journal article
2016

Synthesis of N-substituted 4-hydroxynaphthalimides using palladium-catalysed hydroxylation

C Fleming, T Nalder, E Doeven, C Barrow, F Pfeffer, T Ashton

(2016), Vol. 126, pp. 118-120, Dyes and pigments, Amsterdam, The Netherlands, C1

journal article

Coassembled nanostructured bioscaffold reduces the expression of proinflammatory cytokines to induce apoptosis in epithelial cancer cells

R Li, S Pavuluri, K Bruggeman, B Long, A Parnell, A Martel, S Parnell, F Pfeffer, A Dennison, K Nicholas, C Barrow, D Nisbet, R Williams

(2016), Vol. 12, pp. 1397-1407, Nanomedicine: Nanotechnology, Biology, and Medicine, United States, C1

journal article

Using steric bulk for selective recognition; Blocking the binding site to differentiate guests

R Robson, F Pfeffer

(2016), Vol. 52, pp. 8719-8721, Chemical Communications, England, C1

journal article

Desymmetrization of an Octahedral Coordination Complex Inside a Self-Assembled Exoskeleton

M Johnstone, E Schwarze, J Ahrens, D Schwarzer, J Holstein, B Dittrich, F Pfeffer, G Clever

(2016), Vol. 22, pp. 10791-10795, Chemistry - A European Journal, Germany, C1

journal article

4-Hydroxy-N-propyl-1,8-naphthalimide esters: New fluorescence-based assay for analysing lipase and esterase activity

T Nalder, T Ashton, F Pfeffer, S Marshall, C Barrow

(2016), Vol. 128-129, pp. 127-132, Biochimie, France, C1

journal article

Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation

V Gaur, T Connor, A Sanigorski, S Martin, C Bruce, D Henstridge, S Bond, K McEwen, L Kerr-Bayles, T Ashton, C Fleming, M Wu, L Pike Winer, D Chen, G Hudson, J Schwabe, K Baar, M Febbraio, P Gregorevic, F Pfeffer, K Walder, M Hargreaves, S McGee

(2016), Vol. 16, pp. 2802-2810, Cell Reports, United States, C1

journal article
2015

On the use of 'shortcuts' in the method of continuous variation (Job's method)

B Long, F Pfeffer

(2015), Vol. 27, pp. 136-140, Supramolecular chemistry, London, Eng., C1

journal article

Organogelators based on the norbornane scaffold

S Hickey, S Tripcony, R Li, R Williams, F Pfeffer

(2015), Vol. 27, pp. 425-435, Supramolecular chemistry, Oxford, Eng., C1

journal article

Modular synthesis of linear Bis- and Tris-monodentate fused [6]Polynorbornane-Based Ligands and their assembly into coordination cages

M Johnstone, E Schwarze, G Clever, F Pfeffer

(2015), Vol. 21, pp. 3948-3955, Chemistry : a European journal, London, Eng., C1

journal article

Luminescent probes for the bioimaging of small anionic species in vitro and in vivo

T Ashton, K Jolliffe, F Pfeffer

(2015), Vol. 44, pp. 4547-4595, Chemical society reviews, Cambridge, Eng., C1

journal article

Facile synthesis of guanidine functionalised building blocks

S Hickey, T Ashton, F Pfeffer

(2015), Vol. 4, pp. 320-326, Asian journal of organic chemistry, Weinheim, Germany, C1

journal article

A fluorescent histone deacetylase (HDAC) inhibitor for cellular imaging

C Fleming, T Ashton, C Nowell, M Devlin, A Natoli, J Schreuders, F Pfeffer

(2015), Vol. 51, pp. 7827-7830, Chemical communications, London, Eng., C1

journal article

Synthesis of norbornane bisether antibiotics via silver-mediated alkylation

S Hickey, T Ashton, J White, J Li, R Nation, H Yu, A Elliott, M Butler, J Huang, M Cooper, F Pfeffer

(2015), Vol. 5, pp. 28582-28596, RSC advances, London, Eng., C1

journal article

Rapid domino [3+2] cycloaddition, [4+2] cycloreversion, ring-opening and aromatisation of a fused oxanorbornane substrate

M Johnstone, F Pfeffer

(2015), Vol. 56, pp. 2754-2757, Tetrahedron letters, Amsterdam, The Netherlands, C1

journal article

Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agents

S Hickey, T Ashton, S Khosa, R Robson, J White, J Li, R Nation, H Yu, A Elliott, M Butler, J Huang, M Cooper, F Pfeffer

(2015), Vol. 13, pp. 6225-6241, Organic and biomolecular chemistry, Cambridge, Eng., C1

journal article

Photoredox catalysis of intramolecular cyclizations with a reusable silica-bound ruthenium complex

G Barbante, T Ashton, E Doeven, F Pfeffer, D Wilson, L Henderson, P Francis

(2015), Vol. 7, pp. 1655-1658, ChemCatChem, London, Eng., C1

journal article

Synthesis of 2-(Benzylthio)-4-(trifluoromethyl)thiazole-5-carboxylates using S -benzylisothiouronium halides as thiol equivalents

S Hickey, J White, F Pfeffer, T Ashton

(2015), Vol. 26, pp. 1759-1763, Synlett: accounts and rapid communications in synthetic organic chemistry, Stuttgart, Germany, C1

journal article

Solid-state NMR as a probe of anion binding: molecular dynamics and associations in a [5]polynorbornane bisurea host complexed with terephthalate

A Rawal, J Hook, R Robson, D Gunzelmann, F Pfeffer, L O'Dell

(2015), Vol. 17, pp. 22195-22203, Physical chemistry chemical physics, Cambridge, Eng., C1

journal article

Blue electrogenerated chemiluminescence from water-soluble iridium complexes containing sulfonated phenylpyridine or tetraethylene glycol derivatized triazolylpyridine ligands

E Kerr, E Doeven, G Barbante, T Connell, P Donnelly, D Wilson, T Ashton, F Pfeffer, P Francis

(2015), Vol. 21, pp. 14987-14995, Chemistry, Weinheim, Germany, C1

journal article

Norbornene-based anion receptors as D-alanine binders

B Long, F Pfeffer

(2015), Vol. 27, pp. 847-853, Supramolecular chemistry, London, Eng., C1

journal article
2014

Bis-thiourea macrocycles incorporating fused [n]polynorbornanes: binding of flexible versus rigid dicarboxylates

M Johnstone, F Pfeffer

(2014), Vol. 26, pp. 202-206, Supramolecular chemistry, Abingdon, England, C1

journal article

The influence of the framework : an anion-binding study using fused [n]polynorbornanes

B Long, F Pfeffer

(2014), Vol. 9, pp. 1091-1098, Chemistry : an Asian journal, Berlin, Germany, C1

journal article

Improved synthesis and structural reassignment of MC1568 : a class IIa selective HDAC inhibitor

C Fleming, T Ashton, V Gaur, S McGee, F Pfeffer

(2014), Vol. 57, pp. 1132-1135, Journal of medicinal chemistry, Washington, DC, C1

journal article

Characterisation of lipase fatty acid selectivity using novel omega-3 pNP-acyl esters

T Nalder, S Marshall, F Pfeffer, C Barrow

(2014), Vol. 6, pp. 259-269, Journal of functional foods, Amsterdam, The Netherlands, C1

journal article

Synthesis of 4-amino substituted 1,8-naphthalimide derivatives using palladium-mediated amination

C Fleming, T Ashton, F Pfeffer

(2014), Vol. 109, pp. 135-143, Dyes and pigments, Amsterdam, The Netherlands, C1

journal article
2013

Conformationally preorganised hosts for anions using norbornane and fused [n]polynorbornane frameworks

A Lowe, B Long, F Pfeffer

(2013), Vol. 49, pp. 3376-3388, Chemical communications, Cambridge, England, C1

journal article

Rapid solvent-free synthesis of pyridyl-functionalised [5]polynorbornane- based ligands for metal-organic rings and cages

M Johnstone, M Frank, G Clever, F Pfeffer

(2013), Vol. 2013, pp. 5848-5853, European journal of organic chemistry, London, England, C1

journal article
2012

Rapid formation of diphenylmethyl ethers and thioethers using microwave irradiation and protic ionic liquids

J Altimari, J Delaney, L Servinis, J Squire, M Thornton, S Khosa, B Long, M Johnstone, C Fleming, F Pfeffer, S Hickey, M Wride, T Ashton, B Fox, N Byrne, L Henderson

(2012), Vol. 53, pp. 2035-2039, Tetrahedron letters, Oxford, England, C1

journal article

Determining binding constants from 1H NMR titration data using global and local methods : a case study using [n]polynorbornane-based anion hosts

A Lowe, F Pfeffer, P Thordarson

(2012), Vol. 240-241, pp. 585-594, Supramolecular chemistry, Essex, England, C1

journal article

Asymmetric induction in domino Heck-aza-Michael reactions

D Priebbenow, S Stewart, F Pfeffer

(2012), Vol. 53, pp. 1468-1471, Tetrahedron letters, Oxford, England, C1

journal article

Accessing highly-halogenated flavanones using protic ionic liquids and microwave irradiation

M Thornton, L Henderson, N Byrne, F Pfeffer

(2012), Vol. 16, pp. 121-126, Current organic chemistry, Bussum, Netherlands, C1

journal article

An optimised synthesis of 2-[2,3-Bis(tert-butoxycarbonyl)guanidino]ethylamine

S Hickey, T Ashton, S Khosa, F Pfeffer

(2012), Vol. 23, pp. 1779-1782, Synlett, Stuttgart, Germany, C1

journal article

Examples of regioselective anion recognition among a family of two-, three-, and four-'armed' bis-, tris-, and tetrakis(thioureido) [n]polynorbornane hosts

A Lowe, B Long, F Pfeffer

(2012), Vol. 77, pp. 8507-8517, Journal of organic chemistry, Washington, D. C., C1

journal article
2011

A general approach to N-heterocyclic scaffolds using domino Heck-aza-Michael reactions

D Priebbenow, S Stewart, F Pfeffer

(2011), Vol. 9, pp. 1508-1515, Organic and biomolecular chemistry, Cambridge, U. K., C1

journal article

A one-pot, three-component approach to functionalised tetrahydroisoquinolines using domino Heck-aza-Michael reactions

D Priebbenow, F Pfeffer, S Stewart

(2011), Vol. 2011, pp. 1632-1635, European journal of organic chemistry, Weinheim, Germany, C1

journal article

Simultaneous control of spectroscopic and electrochemical properties in functionalised electrochemiluminescent tris(2,2'-bipyridine)ruthenium(II) complexes

G Barbante, C Hogan, D Wilson, N Lewcenko, F Pfeffer, N Barnett, P Francis

(2011), Vol. 136, pp. 1329-1338, Analyst, Cambridge, United Kingdom, C1

journal article
2010

Rapid synthesis of cyclobutene diesters using a microwave-accelerated ruthenium-catalysed [2+2] cycloaddition

M Johnstone, A Lowe, L Henderson, F Pfeffer

(2010), Vol. 51, pp. 5889-5891, Tetrahedron letters, Oxford, England, C1

journal article

Domino Heck-Aza-Michael reactions : efficient access to 1-substituted tetrahydro-β-carbolines

D Priebbenow, L Henderson, F Pfeffer, S Stewart

(2010), Vol. 75, pp. 1787-1790, Journal of organic chemistry, Washington, D.C., C1

journal article

Developing an anion host for lipid A binding and antibacterial activity

L Henderson, J Li, R Nation, T Velkov, F Pfeffer

(2010), Vol. 46, pp. 3197-3199, Chemical communications, Cambridge, England, C1

journal article

Colorimetric and fluorescent anion sensors : an overview of recent developments in the use of 1,8-naphthalimide-based chemosensors

R Duke, E Veale, F Pfeffer, P Kruger, T Gunnlaugsson

(2010), Vol. 39, pp. 3936-3953, Chemical society reviews, Cambridge, England, C1

journal article
2009

Fluorescence and conductivity studies on wool

A Kaynak, R Foitzik, F Pfeffer

(2009), Vol. 113, pp. 480-484, Materials chemistry and physics, Basel, Switzerland, C1

journal article

Evaluation of tris(4,7-diphenyl-1,10-phenanthrolinedisulfonate)ruthenium(II) as a chemiluminescence reagent

G McDermott, E Zammit, E Bowen, M Cooke, J Adcock, X Conlan, F Pfeffer, N Barnett, G Dyson, P Francis

(2009), Vol. 634, pp. 222-227, Analytica chimica acta, Amsterdam, The Netherlands, C1

journal article

Comparison of homoleptic and heteroleptic 2,2' -bipyridine and 1,10-phenanthroline ruthenium complexes as chemiluminescence and ectrochemiluminescence reagents in aqueous solution

M Cooke, E Doeven, C Hogan, J Adcock, G McDermott, X Conlan, N Barnett, F Pfeffer, P Francis

(2009), Vol. 635, pp. 94-101, Analytica chimica acta, Amsterdam, Netherlands, C1

journal article

Microwave-accelerated 1,3-dipolar cycloaddition for the formation of fused [n]polynorbornanes

R Foitzik, A Lowe, F Pfeffer

(2009), Vol. 50, pp. 2583-2584, Tetrahedron letters, Amsterdam, The Netherlands, C1

journal article

Binding of the terephthalate dianion by di- tri- and tetrathiourea

A Lowe, F Pfeffer

(2009), Vol. 7, pp. 4233-4240, Organic & biomolecular chemistry, Cambridge, England, C1

journal article

Demonstration of bidirectional photoinduced electron transfer (PET) sensing

E Veale, G Tocci, F Pfeffer, P Kruger, T Gunnlaugsson

(2009), Vol. 7, pp. 3447-3454, Organic & biomolecular chemistry, Cambridge, England, C1

journal article
2008

The presence of GABA in gastropod mucus and its role in inducing larval settlement

P Laimek, S Clark, M Stewart, F Pfeffer, W Chaitip, P Hanna, P Sobhon

(2008), Vol. 354, pp. 182-191, Journal of experimental marine biology and ecology, Amsterdam, The Netherlands, C1

journal article

A screening test for heroin based on sequential injection analysis with dual-reagent chemiluminescence detection

L Hill, C Lenehan, P Francis, J Adcock, M Gange, F Pfeffer, N Barnett

(2008), Vol. 76, pp. 674-679, Talanta, Amsterdam, The Netherlands, C1

journal article

Size matters-strong binding of the terephthalate dianion by thiourea functionalised fused [n]polynorbornane hosts

A Lowe, F Pfeffer

(2008), pp. 1871-1873, Chemical communications, London, England, C1

journal article

Factors influencing anion binding stoichiometry : the subtle influence of electronic effects

A Lowe, G Dyson, F Pfeffer

(2008), Vol. 2008, pp. 1559-1567, European journal of organic chemistry, Germany, C1

journal article

Chemiluminescence detection of opium poppy (papaver somniferum) alkaloids

P Francis, J Adcock, J Costin, S Purcell, F Pfeffer, N Barnett

(2008), Vol. 48, pp. 508-518, Journal of pharmaceutical and biomedical analysis, Netherlands, C1

journal article
2007

Synthesis and polymerisation of α,ω-bis(3-pyrrolyl)alkanes

R Foitzik, A Kaynak, F Pfeffer

(2007), Vol. 63, pp. 4237-4242, Tetrahedron, Oxford, England, C1

journal article

Molecular recognition of DNA by rigid [n]-polynorbornane-derived bifunctional intercalators: synthesis and evaluation of their binding properties

L Van Vliet, T Ellis, P Foley, L Liu, F Pfeffer, R Russell, R Warrener, F Hollfelder, M Waring

(2007), Vol. 50, pp. 2326-2340, Journal of medicinal chemistry, Wash. D.C., C1

journal article

Indole as a scaffold for anion recognition

F Pfeffer, K Lim, K Sedgwick

(2007), Vol. 5, pp. 1795-1799, Organic and biomolecular chemistry, Cambridge, England, C1

journal article

Steric and electronic factors influencing recognition by a simple, charge neutral norbornene based anion receptor

A Lowe, G Dyson, F Pfeffer

(2007), Vol. 5, pp. 1343-1346, Organic and biomolecular chemistry, Cambridge, England, C1

journal article

Anion recognition and anion-mediated self-assembly with thiourea-functionalised fused [3]polynorbornyl frameworks

F Pfeffer, P Kruger, T Gunnlaugsson

(2007), Vol. 5, pp. 1894-1902, Organic and biomolecular chemistry, Cambrigde, England, C1

journal article

Conductive poly(α,ω-bis(3-pyrrolyl)alkanes)-coated wool fabrics

R Foitzik, A Kaynak, F Pfeffer

(2007), Vol. 157, pp. 534-539, Synthetic metals, Lausanne, Switzerland, C1

journal article

Synthesis and polymerization studies of 3-(+) and (-) -menthyl carboxylate pyrroles

R Foitzik, E Bowen, A Taylor, F Pfeffer, A Kaynak

(2007), Vol. 157, pp. 924-929, Synthetic metals, Lausanne, Switzerland, C1

journal article
2006

Application of soluble poly (3-alkylpyrrole) polymers on textiles

R Foitzik, A Kaynak, F Pfeffer

(2006), Vol. 156, pp. 637-642, Synthetic metals, Lausanne, Switzerland, C1

journal article

Investigation into the temporal stability of aqueous standard solutions of psilocin and psilocybin using high performance liquid chromatography

N Anastos, N Barnett, S Lewis, F Pfeffer

(2006), Vol. 46, pp. 91-96, Science & justice, Amsterdam, The Netherlands, C1

journal article

Synthesis, polymerization and wool coating studies of 3-iso-butylpyrrole and 3-iso-pentylpyrrole

R Foitzik, A Kaynak, F Pfeffer, J Beckmann

(2006), Vol. 156, pp. 1333-1340, Synthetic metals, Lausanne, Switzerland, C1

journal article

Fluorescent anion sensors based on 4-amino-1,8-naphthalimide that employ the 4-amino N-H

F Pfeffer, M Seter, N Lewcenko, N Barnett

(2006), Vol. 47, pp. 5241-5245, Tetrahedron letters, Amsterdam, The Netherlands, C1

journal article

Anion recognition and sensing in organic and aqueous media using luminescent and colorimetric sensors

T Gunnlaugsson, M Glynn, G Tocci, P Kruger, F Pfeffer

(2006), Vol. 250, pp. 3094-3117, Coordination chemistry reviews, Amsterdam, Netherlands, C1

journal article
2005

Soluble poly-3-alkylpyrrole polymers on films and fabrics

R Foitzik, A Kaynak, J Beckmann, F Pfeffer

(2005), Vol. 155, pp. 185-190, Synthetic metals, Lausanne, Switzerland, C1

journal article

Anion recongnition using preorganized thiourea functionalized [3]polynorbornane receptors

F Pfeffer, T Gunnlaugsson, P Jensen, P Kruger

(2005), Vol. 7, pp. 5357-5360, Organic letters, Washington, D.C., C1

journal article

4-Amino-1,8-naphthalimide-based anion receptors: employing the naphthalimide N-H moiety in the cooperative binding of dihydrogenphosphate

F Pfeffer, A Buschgens, N Barnett, T Gunnlaugsson, P Kruger

(2005), Vol. 46, pp. 6579-6584, Tetrahedron letters, Amsterdam, The Netherlands, C1

journal article

Fluorescent photoinduced electron transfer (PET) sensors for anions; from design to potential application

T Gunnlaugsson, H Ali, M Glynn, P Kruger, G Hussey, F Pfeffer, C dos Santos, J Tierney

(2005), Vol. 15, pp. 287-299, Journal of fluorescence, Dordrecht, The Netherlands, C1

journal article
2003

Strategies and methods for the attachment of amino acids and peptides to chiral [n]polynorbornane templates

F Pfeffer, R Russell

(2003), Vol. 1, pp. 1845-1851, Organic and biomolecular chemistry, Cambridge, England, C1

journal article

Simple naphthalimide based anion sensors: deprotonation induced colour changes and CO2 fixation

T Gunnlaugsson, P Kruger, P Jensen, F Pfeffer, G Hussey

(2003), Vol. 44, pp. 8909-8913, Tetrahedron letters, Amsterdam, The Netherlands, C1-1

journal article

Dual responsive chemosensors for anions : the combination of fluorescent PET (Photoinduced Electron Transfer) and colorimetric chemosensors in a single molecule

T Gunnlaugsson, P Kruger, T Lee, R Parkesh, F Pfeffer, G Hussey

(2003), Vol. 44, pp. 6575-6578, Tetrahedron letters, Amsterdam, The Netherlands, C1-1

journal article
2002

Synthesis of [n]polynorbornanes with differing edge substitution: a new class of regioselectively addressable framework

F Pfeffer, R Russell

(2002), Vol. 1, pp. 2680-2685, Journal of the Chemical Society. Perkin transactions., Cambridge, England, C1

journal article
2000

New and improved 'LEGO' BLOCK protocols for the direct synthesis of hydrophilic ribbon molecules with acid, ester or peptide functionality

R Warrener, D Butler, D Margetic, F Pfeffer, R Russell

(2000), Vol. 41, pp. 4671-4675, Tetrahedron letters, Amsterdam, The Netherlands, C1-1

journal article
1992

LANDFILL LEACHATE EFFECTS ON SORPTION OF ORGANIC MICROPOLLUTANTS ONTO AQUIFER MATERIALS

T LARSEN, T CHRISTENSEN, F PFEFFER, C ENFIELD

(1992), Vol. 9, pp. 307-324, JOURNAL OF CONTAMINANT HYDROLOGY, C1-1

journal article

LANDFILL LEACHATE EFFECTS ON TRANSPORT OF ORGANIC-SUBSTANCES IN AQUIFER MATERIALS

F PFEFFER, C ENFIELD

(1992), Vol. 491, pp. 194-204, Proceedings of the 65th Annual Colloid and Surface Science Symposium 1991, Norman, Ok., E1-1

conference

Funded Projects at Deakin

Australian Competitive Grants

Innovative Technology for At-Scene Forensic Analysis using Microfluidics and Chemiluminescence

Prof Neil Barnett, A/Prof Simon Lewis, A/Prof Fred Pfeffer, Prof Peter Fielden, Dr Gillian Greenway

ARC Linkage - Projects Rnd 1

  • 2008: $76,321
  • 2007: $72,265
  • 2006: $68,324

Discovery and development of novel insulin sensitising compounds for the treatment of Type 2 diabetes

Prof Ken Walder, A/Prof Fred Pfeffer, Dr Nicky Konstantopoulos, Dr Guy Krippner

ARC Linkage - Projects Rnd 1

  • 2012: $139,973
  • 2011: $88,130
  • 2010: $86,763

Biomolecular applications of supramolecular anion recognition chemistry

Prof Katrina Jolliffe, A/Prof Fred Pfeffer, Prof Philip Gale, Prof Thorfinnur Gunnlaugsson

ARC - Discovery Projects

  • 2016: $55,000
  • 2015: $55,000
  • 2014: $55,000

Correlative Imaging of Brain Lipids

Dr Mark Hackett, A/Prof Fred Pfeffer

ARC - Discovery Projects

  • 2024: $18,303
  • 2023: $33,606
  • 2022: $34,106

Other Public Sector Funding

Innovative Technology for At-Scene Forensic Analysis using Microfluidics and Chemiluminescence

Prof Neil Barnett, A/Prof Simon Lewis, A/Prof Fred Pfeffer, Prof Peter Fielden, Dr Gillian Greenway

VPFSD Victoria Police Forensic Services Department

  • 2008: $33,000
  • 2007: $33,500
  • 2006: $33,500

Industry and Other Funding

Discovery and development of novel insulin sensitising compounds for the treatment of Type 2 diabetes

Prof Ken Walder, A/Prof Fred Pfeffer, Dr Nicky Konstantopoulos, Dr Guy Krippner

Verva Pharmaceuticals Ltd

  • 2012: $127,200
  • 2011: $174,725
  • 2010: $146,043

Enhancing the solubility and chelation properties of humic acid solution.

A/Prof Fred Pfeffer

FHF Australia Pty Ltd

  • 2018: $10,324

Supervisions

Principal Supervisor
2022

Gareth Boer

Thesis entitled: The Development of Potent, Broad Spectrum Norbornane-based Antibacterial Agents

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

2021

Elley Rudebeck

Thesis entitled: Mono- and di-substituted 1,8-naphthalimides for cellular imaging and medicinal chemistry

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

2020

Kyle Hearn

Thesis entitled: Direct amidation of 1,8-naphthalimides to access fluorescent HDAC6-selective Scriptaid analogues

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2018

Jordan Ryan Engstrom

Thesis entitled: Using Metals with Norbornenes and Fused [n] Polynorbornanes

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

2017

Ryan Robson

Thesis entitled: Further supramolecular chemistry of fused [n]polynorbornanes in solution and solid-state

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

2015

Shane Matthew Hickey

Thesis entitled: Norbornane-based Peptidomimetics as Antibacterial Agents

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

Cassandra Fleming

Thesis entitled: Development of Fluorescent and Class Selective HDAC Inhibitors

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

2014

Mark Johnstone

Thesis entitled: Conformationally preorganised hosts for Anion recognition and Sensing

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

Benjamin Long

Thesis entitled: Understanding and Applying Fused [n]Polynorbornane Scaffolds in Supramolecular Chemistry

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Simren Kaur Khosa

Thesis entitled: Peptide Mimics Targeting Bacterial Membranes

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

2013

Megan Thornton

Thesis entitled: SYNTHESIS OF FLAVONOIDS AND FLAVONOID-BASED DESIGNED MULTIPLE LIGANDS FOR HYPERTENSION

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2011

Daniel Priebbenow

Thesis entitled: A Novel Palladium-Catalysed Approach to Functionalised N-Heterocycles

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2010

Adam Lowe

Thesis entitled: Norbornenes and [n]Polynorbornanes as Molecular Scaffolds for Anion Recognition

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Marianne Seter

Thesis entitled: Novel Routes to Chiral Rings and Cages

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2007

Naomi Anne Lewcenko

Thesis entitled: The Design and Evaluation of Two Types of Chemical Sensor

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Co-supervisor
2023

Dominic Andreas Renggli

Thesis entitled: Production and Characterisation of Alginate-Hydrogel-Based Short Fibres

Doctor of Philosophy (Engineering), Institute for Frontier Materials

Associate Supervisor
2023

Purvi Mathur

Thesis entitled: Bioremediation of Recalcitrant Pharmaceutical Contaminants Containing Antibiotics in Wastewater

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Arshi Gupta

Thesis entitled: Redox-Active Microbial Metabolites as Sustainable Optoelectronic Materials

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2021

Andrew Leung

Thesis entitled: Investigation and isolation of Xanthones and bioactive compounds from mangosteen.

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

2016

Jarrad Altimari

Thesis entitled: Investigations into 1,2,3-Triazoles for use in Medicinal Chemistry

Doctor of Philosophy (Life & Env), Institute for Frontier Materials

2014

Rebecca Waite

Thesis entitled: Chemiluminescence from reactions of tris(2,2'-bipyridyl)ruthenium(III) with benzyl and phenylpiperazines

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2013

Joshua Delaney

Thesis entitled: The Synthesis and Evaluation of Novel, C2-Symmetric Organocatalysts

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

2012

Christopher Hindson

Thesis entitled: Mechanisms of Light Producing Chemical Reactions

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2010

Sara Ann Bellomarino

Thesis entitled: The Determination of Bioactive Compounds using HPLC with Chemiluminescence Detection

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Stephen Moran

Thesis entitled: Setting the Foundation for Molecular Nuts and Bolts

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2008

Jacqui Louise Francis

Thesis entitled: Applications and Fundamental understanding of Selected Analytically important Chemiluminescence Reactions

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Shona Clark

Thesis entitled: Innovative Analytical Chemistry for Monitoring Wine Producation

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2007

Richard Foitzik

Thesis entitled: Novel Conducting Polymer Films and Coated Textiles

Doctor of Philosophy (Engineering), Institute for Frontier Materials