Dr Greg Kowalski

Bile acids mediate fructose-associated liver tumour growth in mice

S Hargett, S Lahiri, G Kowalski, S Corley, M Nelson, C Lackner, E Olzomer, I Aleksovska, B Hearn, R Shrestha, M Janitz, M Gorrell, C Bruce, M Wilkins, K Hoehn, F Byrne

(2024), Vol. 1870, pp. 167029-167029, Biochimica et Biophysica Acta - Molecular Basis of Disease, Netherlands, C1

The impact of a single dose of whey protein on glucose flux and metabolite profiles in normoglycemic males: insights into glucagon and insulin biology

Teddy Ang, Shaun Mason, Giang Dao, Clinton Bruce, Greg Kowalski

(2023), American Journal of Physiology-Endocrinology and Metabolism, United States, C1

Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity

S Martin, T Connor, A Sanigorski, K McEwen, D Henstridge, B Nijagal, D De Souza, D Tull, P Meikle, G Kowalski, C Bruce, P Gregorevic, M Febbraio, F Collier, K Walder, S McGee

(2023), Vol. 14, pp. 1-13, Cell Death and Disease, Berlin, Germany, C1

Effects of antipsychotic drugs on energy metabolism

B Panizzutti, C Bortolasci, B Spolding, S Kidnapillai, T Connor, S Martin, T Truong, Z Liu, L Gray, G Kowalski, S McGee, J Kim, M Berk, K Walder

(2023), European Archives of Psychiatry and Clinical Neuroscience, Germany, C1

Creatine supplementation reduces the cerebral oxidative and metabolic stress responses to acute in utero hypoxia in the late-gestation fetal sheep

N Tran, G Kowalski, A Muccini, I Nitsos, N Hale, R Snow, D Walker, S Ellery

(2022), Vol. 600, pp. 3193-3210, Journal of Physiology, London, Eng., C1

Insulin sensitivity is preserved in mice made obese by feeding a high starch diet

A Brandon, L Small, T Nguyen, E Suryana, H Gong, C Yassmin, S Hancock, T Pulpitel, S Stonehouse, L Prescott, M Kebede, B Yau, L Quek, G Kowalski, C Bruce, N Turner, G Cooney

(2022), Vol. 11, eLife, England, C1

An Ethanolic Extract of Artemisia dracunculus L. Enhances the Metabolic Benefits of Exercise in Diet-induced Obese Mice

T Allerton, G Kowalski, J Stampley, B Irving, J Lighton, Z Floyd, J Stephens

(2021), Vol. 53, pp. 712-723, Medicine and science in sports and exercise, United States, C1

Autophagy is not involved in lipid accumulation and the development of insulin resistance in skeletal muscle

María Morales-Scholz, Courtney Swinton, Robyn Murphy, Greg Kowalski, Clinton Bruce, Kirsten Howlett, Christopher Shaw

(2021), Vol. 534, pp. 533-539, Biochemical and Biophysical Research Communications, Amsterdam, The Netherlands, C1

Insulin resistance in type 1 diabetes managed with metformin (INTIMET): Study protocol of a double-blind placebo-controlled, randomised trial

J Snaith, D Samocha-Bonet, J Evans, Z Liu, G Kowalski, C Bruce, D Holmes-Walker, J Greenfield

(2021), Vol. 38, Diabetic Medicine, England, C1

Translating glucose tolerance data from mice to humans: Insights from stable isotope labelled glucose tolerance tests

C Bruce, S Hamley, T Ang, K Howlett, C Shaw, G Kowalski

(2021), Vol. 53, Molecular Metabolism, Germany, C1

Baseline serum amino acid levels predict treatment response to augmentation with N-acetylcysteine (NAC) in a bipolar disorder randomised trial

C Bortolasci, A Turner, M Mohebbi, Z Liu, M Ashton, L Gray, W Marx, A Walker, G Kowalski, F Jacka, M Berk, O Dean, K Walder

(2021), Vol. 142, pp. 376-383, Journal of Psychiatric Research, England, C1

The effects of early-onset pre-eclampsia on placental creatine metabolism in the third trimester

S Ellery, P Murthi, P Gatta, A May, M Davies-Tuck, G Kowalski, D Callahan, C Bruce, E Wallace, D Walker, H Dickinson, R Snow

(2020), Vol. 21, International Journal of Molecular Sciences, Switzerland, C1

Mapping the associations of the plasma lipidome with insulin resistance and response to an oral glucose tolerance test

H Beyene, S Hamley, C Giles, K Huynh, A Smith, M Cinel, N Mellet, M Morales-Scholz, D Kloosterman, K Howlett, G Kowalski, C Shaw, D Magliano, C Bruce, P Meikle

(2020), Vol. 105, pp. E1041-E1055, Journal of Clinical Endocrinology and Metabolism, United States, C1

Dynamic glucose disposal is driven by reduced endogenous glucose production in response to voluntary wheel running: A stable isotope approach

T Allerton, G Kowalski, H Hang, J Stephens

(2020), Vol. 319, pp. E2-E10, American Journal of Physiology - Endocrinology and Metabolism, Bethesda, Md., C1

Ultrahigh-Resolution Mass Spectrometry Method for Resolving ¹³C-Enrichment Patterns in a Microalgal Lipidome

S Elahee Doomun, S Nie, S Loke, G Kowalski, P Beech, D Callahan

(2020), Vol. 31, pp. 1763-1772, Journal of the American Society for Mass Spectrometry, United States, C1

The assimilation of glycerol into lipid acyl chains and associated carbon backbones of Nannochloropsis salina varies under nitrogen replete and deplete conditions

N Poddar, S Elahee Doomun, D Callahan, G Kowalski, G Martin

(2020), Vol. 117, pp. 3299-3309, Biotechnology and Bioengineering, United States, C1

An obesogenic maternal environment impairs mouse growth patterns, satellite cell activation, and markers of postnatal myogenesis

J Mikovic, C Brightwell, A Lindsay, Y Wen, G Kowalski, A Russell, C Fry, S Lamon

(2020), Vol. 319, pp. E1008-E1018, American Journal of Physiology - Endocrinology and Metabolism, Bethesda, Md., C1

Loss of protein kinase D activity demonstrates redundancy in cardiac glucose metabolism and preserves cardiac function in obesity

K De Jong, L Hall, M Renton, T Connor, S Martin, G Kowalski, C Shaw, C Bruce, K Howlett, S McGee

(2020), Vol. 42, Molecular Metabolism, Germany, C1

Postprandial aminogenic insulin and glucagon secretion can stimulate glucose flux in humans

T Ang, C Bruce, G Kowalski

(2019), Vol. 68, pp. 939-946, Diabetes, United States, C1

Unicorn babies: Understanding circulating and cerebral creatine levels of the preterm infant. An observational study protocol

M Berry, M Schlegel, G Kowalski, C Bruce, D Callahan, M Davies-Tuck, H Dickinson, A Goodson, A Slocombe, R Snow, D Walker, S Ellery

(2019), Vol. 10, Frontiers in Physiology, Switzerland, C1

Modest changes to glycemic regulation are sufficient to maintain glucose fluxes in healthy young men following overfeeding with a habitual macronutrient composition

Dale Morrison, Greg Kowalski, Clinton Bruce, Glenn Wadley

(2019), Vol. 316, pp. E1061-E1070, American journal of physiology. Endocrinology and metabolism, Bethesda, Md., C1

Reduced insulin action in muscle of high fat diet rats over the diurnal cycle is not associated with defective insulin signaling

L Small, A Brandon, B Parker, V Deshpande, A Samsudeen, G Kowalski, J Reznick, D Wilks, E Preston, C Bruce, D James, N Turner, G Cooney

(2019), Vol. 25, pp. 107-118, Molecular Metabolism, Germany, C1

Phosphatidylserine decarboxylase is critical for the maintenance of skeletal muscle mitochondrial integrity and muscle mass

A Selathurai, G Kowalski, S Mason, D Callahan, V Foletta, P Della Gatta, A Lindsay, S Hamley, G Kaur, A Curtis, M Burch, T Ang, S McGee, C Bruce

(2019), Vol. 27, pp. 33-46, Molecular metabolism, Amsterdam, The Netherlands, C1

Placental creatine metabolism in cases of placental insufficiency and reduced fetal growth

S Ellery, P Murthi, M Davies-Tuck, P Della Gatta, A May, G Kowalski, D Callahan, C Bruce, N Alers, S Miller, J Erwich, E Wallace, D Walker, H Dickinson, R Snow

(2019), Vol. 25, pp. 495-505, Molecular Human Reproduction, England, C1

Mechanisms of hyperinsulinaemia in apparently healthy non-obese young adults: role of insulin secretion, clearance and action and associations with plasma amino acids

S Hamley, D Kloosterman, T Duthie, C Dalla Man, R Visentin, S Mason, T Ang, A Selathurai, G Kaur, M Morales-Scholz, K Howlett, G Kowalski, C Shaw, C Bruce

(2019), Vol. 62, pp. 2310-2324, Diabetologia, Berlin, Germany, C1

Treatment of type 2 diabetes with the designer cytokine IC7Fc

M Findeisen, T Allen, D Henstridge, H Kammoun, A Brandon, L Baggio, K Watt, M Pal, L Cron, E Estevez, C Yang, G Kowalski, L O’Reilly, C Egan, E Sun, L Thai, G Krippner, T Adams, R Lee, J Grötzinger, C Garbers, S Risis, M Kraakman, N Mellet, J Sligar, E Kimber, R Young, M Cowley, C Bruce, P Meikle, P Baldock, P Gregorevic, T Biden, G Cooney, D Keating, D Drucker, S Rose-John, M Febbraio

(2019), Vol. 574, pp. 63-68, Nature, England, C1

Measurement of postprandial glucose fluxes in response to acute and chronic endurance exercise in healthy humans

D Morrison, G Kowalski, E Grespan, A Mari, C Bruce, G Wadley

(2018), Vol. 314, pp. E503-E511, American Journal of Physiology - Endocrinology and Metabolism, United States, C1

AgRP Neurons Require Carnitine Acetyltransferase to Regulate Metabolic Flexibility and Peripheral Nutrient Partitioning

A Reichenbach, R Stark, M Mequinion, R Denis, J Goularte, R Clarke, S Lockie, M Lemus, G Kowalski, C Bruce, C Huang, R Schittenhelm, R Mynatt, B Oldfield, M Watt, S Luquet, Z Andrews

(2018), Vol. 22, pp. 1745-1759, Cell Reports, United States, C1

Endogenous glucose production after sequential meals in humans: Evidence for more prolonged suppression after ingestion of a second meal

Teddy Ang, Greg Kowalski, Clinton Bruce

(2018), Vol. 315, pp. E904-E911, American journal of physiology: endocrinology and metabolism, Bethesda, Md., C1

A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism

N Turner, X Lim, H Toop, B Osborne, A Brandon, E Taylor, C Fiveash, H Govindaraju, J Teo, H McEwen, T Couttas, S Butler, A Das, G Kowalski, C Bruce, K Hoehn, T Fath, C Schmitz-Peiffer, G Cooney, M Montgomery, J Morris, A Don

(2018), Vol. 9, Nature Communications, England, C1

Lysine post-translational modification of glyceraldehyde-3-phosphate dehydrogenase regulates hepatic and systemic metabolism

S Bond, K Howlett, G Kowalski, S Mason, T Connor, A Cooper, V Streltsov, C Bruce, K Walder, S McGee

(2017), Vol. 31, pp. 2592-2602, FASEB journal, Bethesda, Md., C1

Creatine biosynthesis and transport by the term human placenta

S Ellery, P Della Gatta, C Bruce, G Kowalski, M Davies-Tuck, J Mockler, P Murthi, D Walker, R Snow, H Dickinson

(2017), Vol. 52, pp. 86-93, Placenta, Amsterdam, The Netherlands, C1

Does maternal-fetal transfer of creatine occur in pregnant sheep?

S Baharom, R De Matteo, S Ellery, P Della Gatta, C Bruce, G Kowalski, N Hale, H Dickinson, R Harding, D Walker, R Snow

(2017), Vol. 313, pp. E75-E83, American Journal of Physiology - Endocrinology and Metabolism, United States, C1

Resolution of glucose intolerance in long-term high-fat, high-sucrose-fed mice

G Kowalski, M Kraakman, S Mason, A Murphy, C Bruce

(2017), Vol. 233, pp. 269-279, Journal of endocrinology, Bristol, Eng., C1

The effect of ingested glucose dose on the suppression of endogenous glucose production in humans

G Kowalski, S Moore, S Hamley, A Selathurai, C Bruce

(2017), Vol. 66, pp. 2400-2406, Diabetes, United States, C1

PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications

G Lancaster, H Kammoun, M Kraakman, G Kowalski, C Bruce, M Febbraio

(2016), Vol. 7, Nature Communications, England, C1

Overexpression of striated muscle activator of Rho Signaling (STARS) Increases C2C12 skeletal muscle cell differentiation

M Wallace, P Della Gatta, B Mir, G Kowalski, J Kloehn, M McConville, A Russell, S Lamon

(2016), Vol. 7, Frontiers in Physiology, Switzerland, C1

Reversing diet-induced metabolic dysregulation by diet switching leads to altered hepatic de novo lipogenesis and glycerolipid synthesis

G Kowalski, S Hamley, A Selathurai, J Kloehn, D De Souza, S O'Callaghan, B Nijagal, D Tull, M McConville, C Bruce

(2016), Vol. 6, Scientific Reports, England, C1

Strategies for extending metabolomics studies with stable isotope labelling and fluxomics

A Srivastava, G Kowalski, D Callahan, P Meikle, D Creek

(2016), Vol. 6, Metabolites, Switzerland, C1

Analysis of mammalian cell proliferation and macromolecule synthesis using deuteratedwater and gas chromatography-mass spectrometry

V Foletta, M Palmieri, J Kloehn, S Mason, S Previs, M McConville, O Sieber, C Bruce, G Kowalski

(2016), Vol. 6, Metabolites, Switzerland, C1

Overexpression of sphingosine kinase 1 in liver reduces triglyceride content in mice fed a low but not high-fat diet

Greg Kowalski, Joachim Kloehn, Micah Burch, Ahrathy Selathurai, Steven Hamley, Stéphanie Bayol, Séverine Lamon, Matthew Watt, Robert Lee-Young, Malcolm McConville, C Bruce

(2015), Vol. 1851, pp. 210-219, Biochimica et Biophysica Acta (BBA)- molecular and cell biology of lipids, Amsterdam, Netherlands, C1

Application of dynamic metabolomics to examine in vivo skeletal muscle glucose metabolism in the chronically high-fat fed mouse

G Kowalski, D De Souza, M Burch, S Hamley, J Kloehn, A Selathurai, D Tull, S O'Callaghan, M McConville, C Bruce

(2015), Vol. 462, pp. 27-32, Biochemical and Biophysical Research Communications, United States, C1

The CDP-Ethanolamine Pathway Regulates Skeletal Muscle Diacylglycerol Content and Mitochondrial Biogenesis without Altering Insulin Sensitivity.

A Selathurai, G Kowalski, M Burch, P Sepulveda, S Risis, R Lee-Young, S Lamon, P Meikle, A Genders, S McGee, M Watt, A Russell, M Frank, S Jackowski, M Febbraio, C Bruce

(2015), Vol. 21, pp. 718-730, Cell Metabolism, United States, C1

In vivo cardiac glucose metabolism in the high-fat fed mouse: comparison of euglycemic-hyperinsulinemic clamp derived measures of glucose uptake with a dynamic metabolomic flux profiling approach

G Kowalski, D De Souza, S Risis, M Burch, S Hamley, J Kloehn, A Selathurai, R Lee-Young, D Tull, S O'Callaghan, M McConville, C Bruce

(2015), Vol. 463, pp. 818-824, Biochemical and biophysical research communications, Amsterdam, The Netherlands, C1

The regulation of glucose metabolism: implications and considerations for the assessment of glucose homeostasis in rodents

G Kowalski, C Bruce

(2014), Vol. 307, pp. E859-E871, American journal of physiology-endocrinology and metabolism, Bethesda, MD, C1

PLIN5 deletion remodels intracellular lipid composition and causes insulin resistance in muscle

Rachael Mason, Ruzaidi Mokhtar, Maria Matzaris, Ahrathy Selathurai, Greg Kowalski, Nancy Mokbel, Peter Meikle, Clinton Bruce, Matthew Watt

(2014), Vol. 3, pp. 652-663, Molecular metabolism, Amsterdam, Netherlands, C1-1

Plasma sphingosine-1-phosphate is elevated in obesity

G Kowalski, A Carey, A Selathurai, B Kingwell, C Bruce

(2013), Vol. 8, pp. 1-7, PloS one, San Francisco, Calif., C1-1

Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding

N Turner, G Kowalski, S Leslie, S Risis, C Yang, R Lee-Young, J Babb, P Meikle, G Lancaster, D Henstridge, P White, E Kraegen, A Marette, G Cooney, M Febbraio, C Bruce

(2013), Vol. 56, pp. 1638-1648, Diabetologia, Berlin, Germany, C1-1

Overexpression of sphingosine kinase 1 prevents ceramide accumulation and ameliorates muscle insulin resistance in high-fat diet-fed mice

C Bruce, S Risis, J Babb, C Yang, G Kowalski, A Selathurai, R Lee-Young, J Weir, K Yoshioka, Y Takuwa, P Meikle, S Pitson, M Febbraio

(2012), Vol. 61, pp. 3148-3155, Diabetes, Alexandria, Virginia, C1-1

Tumor progression locus 2 (Tpl2) deficiency does not protect against obesity-induced metabolic disease

G Lancaster, G Kowalski, E Estevez, M Kraakman, G Grigoriadis, M Febbraio, S Gerondakis, A Banerjee

(2012), Vol. 7, pp. 1-7, PLoS one, San Francisco, Calif., C1-1

Deficiency of haematopoietic-cell-derived IL-10 does not exacerbate high-fat-diet-induced inflammation or insulin resistance in mice

G Kowalski, H Nicholls, S Risis, N Watson, P Kanellakis, C Bruce, A Bobik, G Lancaster, M Febbraio

(2011), Vol. 54, pp. 888-899, Diabetologia, Berlin, Germany, C1-1

Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue

H Nicholls, G Kowalski, D Kennedy, S Risis, L Zaffino, N Watson, P Kanellakis, M Watt, A Bobik, A Bonen, M Febbraio, G Lancaster, M Febbraio

(2011), Vol. 60, pp. 1100-1110, Diabetes, Alexandria, Va., C1-1

IL-10 controls cystatin C synthesis and blood concentration in response to inflammation through regulation of IFN regulatory factor 8 expression

Y Xu, P Schnorrer, A Proietto, G Kowalski, M Febbraio, H Acha-Orbea, R Dickins, J Villadangos

(2011), Vol. 186, pp. 3666-3673, Journal of immunology, Bethesda, Md., C1-1