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Dr Jacqui Adcock

STAFF PROFILE

Position

Senior Research Fellow

Faculty

Faculty of Sci Eng & Built Env

Department

School of Life & Env. Sciences

Campus

Geelong Waurn Ponds Campus

Contact

jacqui.adcock@deakin.edu.au
+61 3 522 72096

Biography

Dr Adcock is an ARC DECRA fellow, currently developing new chromatographic methods for the analysis of various common lipid types such as fatty acids, sterols and tocopherols. She is also synthesising novel lipid compounds using enzymatic reactions, and in conjunction with this is developing chromatographic methods for the analysis of these compounds. Her work is specifically focussed on omega-3 fatty acids and the anti-inflammatory compounds that can be synthesised from them. These compounds may be beneficial in the treatment of many inflammatory diseases, including arthritis, Alzheimer’s disease, cardiovascular disease, cancer, periodontal disease and allergies.

Previously, Dr Adcock has developed a wide range of new methodology for the analysis of foods, biological fluids, industrial process samples, pharmaceuticals and illicit drugs. During her postdoctoral fellowship at RMIT University, Dr Adcock developed advanced separation techniques, based on comprehensive two-dimensional gas chromatography, for the rapid analysis of essential oil and perfume products, and worked in the R&D department at Firmenich – the world’s second largest flavour and fragrance company – located in Switzerland.

Read more on Jacqui's profile

Research interests

  • Enzymatic synthesis and complete characterization of lipid mediators of inflammation
  • Comprehensive two-dimensional gas chromatography for lipidomics and biomarker discovery

Publications

Filter by

2018

Soy flour as an alternative to purified lipoxygenase for the enzymatic synthesis of resolvin analogues

T Tu, E Dobson, L Henderson, C Barrow, J Adcock

(2018), Vol. 41, pp. 25-33, New biotechnology, Amsterdam, The Netherlands, C1

journal

Electrochemically, spectrally, and spatially resolved annihilation-electrogenerated chemiluminescence of mixed-metal complexes at working and counter electrodes

L Soulsby, D Hayne, E Doeven, L Chen, C Hogan, E Kerr, J Adcock, P Francis

(2018), Vol. 5, pp. 1543-1547, Chemelectrochem, Chichester, Eng., C1

journal

Mixed annihilation electrogenerated chemiluminescence of iridium(iii) complexes

Lachlan Soulsby, David Hayne, Egan Doeven, David Wilson, Johnny Agugiaro, Timothy Connell, Lifen Chen, Conor Hogan, Emily Kerr, Jacqui Adcock, Paul Donnelly, Jonathan White, Paul Francis

(2018), Vol. 20, pp. 18995-19006, Physical chemistry chemical physics, Cambridge, Eng., C1

journal

Detection of biogenic amines in pet food ingredients by RP-HPLC with automated dansyl chloride derivatization

Jessica Learey, Shona Crawford-Clark, Benjamin Bowen, Colin Barrow, Jacqui Adcock

(2018), Vol. 41, pp. 4430-4436, Journal of separation science, Weinheim, Germany, C1

journal
2014

Advances in the use of acidic potassium permanganate as a chemiluminescence reagent: A review

J Adcock, N Barnett, C Barrow, P Francis

(2014), Vol. 807, pp. 9-28, Analytica Chimica Acta, C1

journal

Determination of neurotransmitters and their metabolites using one- and two-dimensional liquid chromatography with acidic potassium permanganate chemiluminescence detection

B Holland, X Conlan, P Stevenson, S Tye, A Reker, N Barnett, J Adcock, P Francis

(2014), Vol. 406, pp. 5669-5676, Analytical and bioanalytical chemistry, Berlin, Germany, C1-1

journal

The importance of chain length for the polyphosphate enhancement of acidic potassium permanganate chemiluminescence

B Holland, J Adcock, P Nesterenko, A Peristyy, P Stevenson, N Barnett, X Conlan, P Francis

(2014), Vol. 842, pp. 35-41, Analytica chimica acta, Amsterdam, The Netherlands, C1

journal

Solvent-induced 7R-dioxygenase activity of soybean 15-lipoxygenase-1 in the formation of omega-3 DPA-derived resolvin analogs

E Dobson, C Barrow, J Adcock

(2014), Vol. 108, pp. 96-102, Journal of molecular catalysis b: enzymatic, London, England, C1

journal

A review of recent advances in chemiluminescence detection using nano-colloidal manganese(IV)

J Adcock, Z Smith, N Barnett, G Barbante, E Doeven, P Francis

(2014), Vol. 848, pp. 1-9, Analytica chimica acta, Amsterdam, Netherlands, C1

journal
2013

Selective concentration of EPA and DHA using Thermomyces lanuginosus lipase is due to fatty acid selectivity and not regioselectivity

T Akanbi, J Adcock, C Barrow

(2013), Vol. 138, pp. 615-620, Food Chemistry, C1

journal

Pollen baiting facilitates the isolation of marine thraustochytrids with potential in omega-3 and biodiesel production

A Gupta, S Wilkens, J Adcock, M Puri, C Barrow

(2013), Vol. 40, pp. 1231-1240, Journal of Industrial Microbiology and Biotechnology, C1

journal

Chemiluminescence evidence supporting the selective role of ligands in the permanganate oxidation of micropollutants

M Roderick, J Adcock, J Terry, Z Smith, S Parry, S Linton, M Thornton, C Barrow, P Francis

(2013), Vol. 117, pp. 10286-10293, Journal of Physical Chemistry A, C1

journal

Controlled formation of mono- and dihydroxy-resolvins from EPA and DHA using soybean 15-lipoxygenase

E Dobson, C Barrow, J Kralovec, J Adcock

(2013), Vol. 54, pp. 1439-1447, Journal of Lipid Research, C1

journal
2012

Chemiluminescence detection of cannabinoids and related compounds with acidic potassium permanganate

B Holland, P Francis, B Li, T Tsuzuki, J Adcock, N Barnett, X Conlan

(2012), Vol. 4, pp. 675-679, Drug testing and analysis, West Sussex, England, C1

journal

Chemiluminescence detection of cannabinoids and related compounds with acidic potassium permanganate.

B Holland, P Francis, B Li, T Tsuzuki, J Adcock, N Barnett, X Conlan

(2012), Vol. 4, pp. 675-679, Drug testing and analysis, C1-1

journal
2011

Chemiluminescence detectors for liquid chromatography

J Adcock, J Terry, C Barrow, N Barnett, D Olson, P Francis

(2011), Vol. 3, pp. 139-144, Drug testing and analysis, West Sussex, England, C1

journal

Chemiluminescence and electrochemiluminescence detection of controlled drugs

J Adcock, C Barrow, N Barnett, X Conlan, C Hogan, P Francis

(2011), Vol. 3, pp. 145-160, Drug Testing and Analysis, C1

journal

Liquid-Phase chemiluminescence detection for HPLC

P Francis, J Adcock

(2011), pp. 221-250, Hyphenated and alternative methods of detection in chromatography, Boca Raton, Fla., B1

chapter

Any old radical won't do: An EPR study of the selective excitation and quenching mechanisms of [Ru(bipy)3]2+ chemiluminescence and electrochemiluminescence

C Hindson, G Hanson, P Francis, J Adcock, N Barnett

(2011), Vol. 17, pp. 8018-8022, Chemistry - A European Journal, C1

journal

Enhanced permanganate chemiluminescence

P Francis, C Hindson, J Terry, Z Smith, T Slezak, J Adcock, B Fox, N Barnett

(2011), Vol. 136, pp. 64-66, Analyst, C1

journal

Kinetics and selectivity of permanganate chemiluminescence: A study of hydroxyl and amino disubstituted benzene positional isomers

T Slezak, Z Smith, J Adcock, C Hindson, N Barnett, P Nesterenko, P Francis

(2011), Vol. 707, pp. 121-127, Analytica Chimica Acta, C1

journal
2010

Determination of citrus aurantium protoalkaloids using HPLC with acidic potassium permanganate chemiluminescence detection

D Percy, J Adcock, X Conlan, N Barnett, M Gange, L Noonan, L Henderson, P Francis

(2010), Vol. 80, pp. 2191-2195, Talanta, Amsterdam, Netherlands, C1

journal

Mechanism of permanganate chemiluminescence

C Hindson, P Francis, G Hanson, J Adcock, N Barnett

(2010), Vol. 82, pp. 4174-4180, Analytical Chemistry, C1

journal

Monolithic column chromatography coupled with chemiluminescence detection

P Francis, J Adcock

(2010), pp. 319-337, Monolithic chromatography and its modern applications, St Albans, England, B1-1

chapter
2009

Evaluation of tris(4,7-diphenyl-1,10-phenanthrolinedisulfonate)ruthenium(II) as a chemiluminescence reagent

G McDermott, E Zammit, E Bowen, M Cooke, J Adcock, X Conlan, F Pfeffer, N Barnett, G Dyson, P Francis

(2009), Vol. 634, pp. 222-227, Analytica Chimica Acta, C1

journal

Comparison of homoleptic and heteroleptic 2,2' -bipyridine and 1,10-phenanthroline ruthenium complexes as chemiluminescence and ectrochemiluminescence reagents in aqueous solution

M Cooke, E Doeven, C Hogan, J Adcock, G McDermott, X Conlan, N Barnett, F Pfeffer, P Francis

(2009), Vol. 635, pp. 94-101, Analytica chimica acta, Amsterdam, Netherlands, C1

journal

Chemiluminescence spectra for the oxidation of sulphite in the presence of fluorescent and non-fluorescent enhancers

J Adcock, P Francis, N Barnett

(2009), Vol. 652, pp. 303-307, Analytica chimica acta, Amsterdam, Netherlands, C1-1

journal

Emitting species in chemiluminescence reactions with acidic potassium permanganate : a re-evaluation based on new spectroscopic evidence

J Adcock, P Francis, N Barnett

(2009), Vol. 19, pp. 867-874, Journal of fluorescence, New York, N.Y., C1-1

journal

Precision milled flow-cells for chemiluminescence detection

S Mohr, J Terry, J Adcock, P Fielden, N Goddard, N Barnett, D Wolcott, P Francis

(2009), Vol. 134, pp. 2233-2238, Analyst, C1-1

journal

Peak modeling approach to accurate assignment of first-dimension retention times in comprehensive two-dimensional chromatography

J Adcock, M Adams, B Mitrevski, P Marriott

(2009), Vol. 81, pp. 6797-6804, Analytical Chemistry, C1-1

journal

Effects of variation in modulator temperature during cryogenic modulation in comprehensive two-dimensional gas chromatography

F Begnaud, C Debonneville, J Probst, A Chaintreau, P Morrison, J Adcock, P Marriott

(2009), Vol. 32, pp. 3144-3151, Journal of Separation Science, C1-1

journal
2008

A screening test for heroin based on sequential injection analysis with dual-reagent chemiluminescence detection

L Hill, C Lenehan, P Francis, J Adcock, M Gange, F Pfeffer, N Barnett

(2008), Vol. 76, pp. 674-679, Talanta, C1

journal

The characteristic red chemiluminescence from reactions with acidic potassium permanganate: Further spectroscopic evidence for a manganese(II) emitter

J Adcock, P Francis, T Smith, N Barnett

(2008), Vol. 133, pp. 49-51, Analyst, C1

journal

Manganese(III) and manganese(IV) as chemiluminescence reagents: A review

A Brown, P Francis, J Adcock, K Lim, N Barnett

(2008), Vol. 624, pp. 175-183, Analytica Chimica Acta, C1

journal

Chemiluminescence detection of opium poppy (Papaver somniferum) alkaloids

P Francis, J Adcock, J Costin, S Purcell, F Pfeffer, N Barnett

(2008), Vol. 48, pp. 508-518, Journal of Pharmaceutical and Biomedical Analysis, C1

journal

Chemiluminescence detector with a serpentine flow cell

J Terry, J Adcock, D Olson, D Wolcott, C Schwanger, L Hill, N Barnett, P Francis

(2008), Vol. 80, pp. 9817-9821, Analytical Chemistry, C1

journal
2007

Acidic potassium permanganate as a chemiluminescence reagent-A review

J Adcock, P Francis, N Barnett

(2007), Vol. 601, pp. 36-67, Analytica Chimica Acta, C1

journal

A hybrid FIA/HPLC system incorporating monolithic column chromatography

J Adcock, P Francis, K Agg, G Marshall, N Barnett

(2007), Vol. 600, pp. 136-141, Analytica chimica acta, Amsterdam, Netherlands, C1

journal
2006

Near-ultraviolet chemiluminescence from the reaction of ammonia with hypobromite in aqueous solution

P Francis, J Adcock, N Barnett

(2006), Vol. 65, pp. 708-710, Spectrochimica acta. Part A, molecular and biomolecular spectroscopy, Amsterdam, Netherlands, C1

journal
2005

Chemiluminescence detection of arginine-containing peptides separated with monolithic high-performance liquid chromatography

P Francis, J Adcock, J Costin, K Agg

(2005), Vol. 336, pp. 141-143, Analytical Biochemistry, C1

journal

Chemiluminescence methods for the determination of ofloxacin

P Francis, J Adcock

(2005), Vol. 541, pp. 3-12, Analytica chimica acta, Amsterdam, The Netherlands, C1

journal

Determination of selected neurotransmitter metabolites using monolithic column chromatography coupled with chemiluminescence detection

J Adcock, N Barnett, J Costin, P Francis, S Lewis

(2005), Vol. 67, pp. 585-589, Talanta, C1

journal

Chemiluminescence detection of arginine-containing peptides separated with monolithic high-performance liquid chromatography

P Francis, J Adcock, J Costin, K Agg

(2005), Vol. 336, pp. 141-143, Analytical biochemistry, Philadelphia, Pa., C1-1

journal
2004

Determination of glyphosate mono-isopropylamine salt in process samples using flow injection analysis with tris(2,2?-bipyridyl)ruthenium(II) chemiluminescence detection

J Adcock, N Barnett, R Gerardi, C Lenehan, S Lewis

(2004), Vol. 64, pp. 534-537, Talanta, C1

journal

Funded Projects at Deakin

Australian Competitive Grants

Enzymatic synthesis, microencapsulation and biological evaluation of a new class of omega-3 derived functional food ingredients

Prof Colin Barrow, Prof Ken Walder, Dr Jaroslav Kralovec, Dr Jacqui Francis, Prof Leigh Ackland, Dr Ian Musgrave, Dr Wei Zhang

ARC Linkage - Projects Rnd 1, ARC_DUAPAI ARC_Deakin University Australian Postgraduate Award Industry

  • 2013: $14,921
  • 2012: $183,043
  • 2011: $159,949
  • 2010: $153,111

Enzymatic synthesis of pro-resolution lipid mediators: Towards new therapeutic strategies for inflammatory diseases

Dr Jacqui Francis

ARC DECRA - Discovery Early Career Researcher Award

  • 2016: $124,183
  • 2015: $163,284
  • 2014: $130,384

Industry and Other Funding

Enzymatic synthesis, microencapsulation and biological evaluation of a new class of omega-3 derived functional food ingredients

Prof Colin Barrow, Prof Ken Walder, Dr Jaroslav Kralovec, Dr Jacqui Francis, Prof Leigh Ackland, Dr Ian Musgrave, Dr Wei Zhang

  • 2012: $70,607
  • 2011: $53,835
  • 2010: $52,910

Other Funding Sources

Olfactory signalling in an avian species complex: the crimson rosella (Platycercus elegans)

Prof Andy Bennett, Dr Mathew Berg, Ms Milla Mihailova, Prof Kate Buchanan, Dr Jacqui Francis

  • 2015: $909

Supervisions

Principal Supervisor
2019

Thi Hoang Anh Tu

Thesis entitled: Enzymatic synthesis of anti-inflammatory lipid mediators using soybean flour lipoxygenase

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

2018

Jessica Jayne Learey

Thesis entitled: Expanding on current methods employed for investigating pet food stability

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Associate Supervisor
2016

Eleanor Dobson

Thesis entitled: Biocatalysis of Soybean 15-Lipoxygenase for the Production of Lipid Mediators of Inflammation

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2014

Taiwo Olusesan Akanbi

Thesis entitled: Characterization and Lipase concentration of omega-3 rich oils

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Tim Nalder

Thesis entitled: Microalgal Lipids, Lipases and Lipase Screening Methods

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences