Biography
Professor Walder is the Chair of Metabolic Diseases in the School of Medicine and the Co-Director of IMPACT Institute. His research focuses on mental health disorders, and in particular the discovery of novel treatments for these diseases. After spending 2 years at the National Institutes of Health in Phoenix, Arizona, Professor Walder returned to Deakin University where he has played a key role in the evolution of the Metabolic Research Unit and the establishment of IMPACT Institute. He has authored more than 150 academic publications and is named as an inventor on more than 40 patent applications. Professor Walder has worked closely with a number of industry partners, and is focused on conducting applied research with tangible outcomes that benefit Australia. In 2014, a compound discovered in Professor Walder’s laboratory successfully completed a Phase 2 clinical trial for the treatment of type 2 diabetes. Current work is focused on using induced pluripotent stem cell technology to repurpose drugs to treat common mental health disorders including bipolar disorder, schizophrenia and major depressive disorder. Prof Walder also recently commenced a new project aiming to repurpose drugs to treat myalgic encephalomyelitis/chronic fatigue syndrome.
Read more on Ken's profileCareer highlights
Recent discovery of several drugs that can be repurposed for the treatment of bipolar disorder and schizophrenia.
Chief Investigator in the new NHMRC funded Centre of Research Excellence for the Development of Innovative Therapies for Psychiatric Disorders ($2.5M, 2019-2024).
A new drug for diabetes discovered in Prof Walder's laboratory successfully completed a phase 2 clinical trial, where it caused a significant reduction in plasma HbA1c levels (Simpson et al. Diabetes Care, 2014).
Research interests
Professor Walder's research is primarily focused on the discovery and validation of novel drug treatments for complex diseases. This research utilises state of the art equipment and technologies, in combination with unique model systems and sample collections, to screen for small molecules that can be used to treat complex diseases. The novel drug candidates are tested in in vitro and in vivo model systems to establish their potential for development as therapeutics.
Professor Walder works closely with the clinical research team at IMPACT, based at University Hospital Geelong, and has a strong focus on translating basic research findings into the clinical research program, with the overarching aim of improving the lives of people with mental health disorders.
Affiliations
Australasian Society for Bipolar and Depressive Disorders, International Society for Bipolar Disorders, Biological Psychiatry Australia, Society for Mental Health Research, World Federation of Societies of Biological Psychiatry
European Association for the Study of Diabetes, American Diabetes Association, Australian Diabetes Society, International Association for the Study of Obesity, North American Association for the Study of Obesity, Australian Society for the Study of Obesity
Teaching interests
Previously supervised 25 PhD and 32 Honours students to successful completions. 1 Current PhD student as Principal Supervisor, 4 as Associate Supervisor.
Unit Chair of HMH900 (Research Design)
Units taught
HMH900 (Research Design)
Knowledge areas
Mental health (major depressive disorder, bipolar disorder, schizophrenia).
Metabolic diseases (obesity, type 2 diabetes, non-alcoholic fatty liver disease).
Genetics.
Drug discovery.
Conferences
Invited presentations at national and international conferences including:
40th Annual Society for Mental Health Research Conference, Noosa, November 2018. Invited seminar presentation: "Targeting microRNAs to screen for new compounds to treat bipolar disorder".
Australasian Society for Bipolar & Depressive Disorders Conference, Melbourne, November 2017. "Drugs used to treat bipolar disorder act via microRNAs to regulate expression of genes involved in neurogenesis and neurite outgrowth".
Biological Psychiatry Australia Annual Conference, Wooloongong, September 2016. "MicroRNA targets to repurpose drugs for bipolar disorder".
Australian Diabetes Society Annual Scientific Meeting, Sydney, August 2013. Invited seminar presentation: “VVP808 and fatty liver disease”.
Baker-IDI Research Institute Seminar Series, Melbourne, October 2011. Invited seminar presentation: “Use of GES technology to discover a new insulin sensitising agent”.
Frontiers in Obesity Research, Melbourne, September 2011. Invited seminar presentation: “VVP808: A novel insulin sensitising agent”.
University of Melbourne Department of Medicine Seminar Series, Melbourne, May 2010. Invited seminar presentation: “VVP808: A novel insulin sensitising agent”.
Monash University Obesity Diabetes Institute, Melbourne, June 2010. Invited seminar presentation: “Mechanism of action of VVP808”.
MSD Diabetes Meeting, Sydney, October 11-12, 2008. Symposium presentation: “Overview of mitochondrial dysfunction in diabetes”.
GTCbio 3rd Metabolic Diseases World Summit, San Diego, USA, November 1-2, 2007. Symposium presentation: “Use of gene expression signatures to discover novel diabetes therapeutics”.
ASSO 15th Annual Scientific Meeting, Canberra, Australia, August 31-September 2, 2007. Symposium presentation: “The adipocyte as an endocrine organ”.
2nd International Congress on Prediabetes and the Metabolic Syndrome, Barcelona, Spain, April 25-28, 2007. Symposium presentation: “The mitochondrial protease PARL and type 2 diabetes”.
2nd Scientific Meeting of the Asia-Pacific Diabetes and Obesity Study Group, Kyoto, Japan, August 26-7, 2006. Symposium presentation: “CXS741, A Novel Secreted Protein Involved in the Pathogenesis of Obesity and Type 2 Diabetes”.
1st Scientific Meeting of the Asia-Pacific Diabetes and Obesity Study Group, Kobe, Japan, August 20-1, 2005. Symposium presentation: “Genetic variation in PSARL is associated with plasma insulin concentration”.
Professional activities
Professor Walder serves as a reviewer for the following journals:
Acta Neuropsychiatrica, Molecular Neurobiology, International Journal of Neuropsychopharmacology, Biological Psychiatry.
Diabetes, Diabetologia, International Journal of Obesity, Molecular and General Genetics, Kidney International, Pancreas
Professor Walder regularly reviews research applications for national and international funding bodies, including NHMRC and ARC.
Awards
1998 Fogarty Fellowship (NIH)
2006 Smart Geelong Network Biotechnology Researcher of the Year
Projects
See current School of Medicine Honours/PhD project booklet.
Current projects include:
Repurposing drugs to treat myalgic encephalomyelitis/chronic fatigue syndrome
Repurposing drugs to treat bipolar disorder
Novel microRNAs involved in the pathophysiology
and treatment of bipolar disorder
Alternative approaches in the treatment of bipolar disorder
Exploration of potential novel therapies for affective disorders
Publications
Metformin is Protective Against the Development of Mood Disorders
J Lake, C Bortolasci, A Stuart, J Pasco, S Kidnapillai, B Spolding, T Truong, B Panizzutti, Z Liu, O Dean, T Crowley, M Richardson, J Kim, M Berk, L Williams, K Walder
(2023), Vol. 56, pp. 25-31, Pharmacopsychiatry, Germany, C1
A Walker, M Mohebbi, M Maes, M Berk, K Walder, C Bortolasci, Z Liu, C Ng, M Ashton, L Berk, A Singh, G Malhi, O Dean
(2023), Vol. 27, Brain, Behavior, and Immunity - Health, C1
S Sithara, T Crowley, K Walder, K Aston-Mourney
(2023), Vol. 15, Islets, C1
Alteration patterns of peripheral concentrations of cytokines and associated inflammatory proteins in acute and chronic stages of schizophrenia: a systematic review and network meta-analysis
Sean Halstead, Dan Siskind, Michaela Amft, Elias Wagner, Vladislav Yakimov, Zoe Shih-Jung Liu, Ken Walder, Nicola Warren
(2023), Vol. 10, pp. 260-271, The Lancet Psychiatry, C1-1
G Morris, K Walder, M Berk, A Carvalho, W Marx, C Bortolasci, A Yung, B Puri, M Maes
(2022), Vol. 114, pp. 1-17, Progress in Neuro-Psychopharmacology and Biological Psychiatry, Amsterdam, The Netherlands, C1
K Mehta, S Thandavan, M Mohebbi, J Pasco, L Williams, K Walder, B Ng, V Gupta
(2022), Vol. 76, pp. 1-13, Ageing Research Reviews, Amsterdam, The Netherlands, C1
G Morris, L Sominsky, K Walder, M Berk, W Marx, A Carvalho, C Bortolasci, M Maes, B Puri
(2022), Vol. 59, pp. 3485-3503, Molecular Neurobiology, Berlin, Germany, C1
Common effects of bipolar disorder medications on expression quantitative trait loci genes
T Truong, C Bortolasci, S Kidnapillai, B Spolding, B Panizzutti, Z Liu, B Watmuff, J Kim, O Dean, M Richardson, M Berk, K Walder
(2022), Vol. 150, pp. 105-112, Journal of Psychiatric Research, Amsterdam, The Netherlands, C1
Trang Truong, Chiara Bortolasci, Briana Spolding, Bruna Panizzutti, Zoe Liu, Srisaiyini Kidnapillai, Mark Richardson, Laura Gray, Craig Smith, Olivia Dean, Jee Kim, Michael Berk, Ken Walder
(2022), Vol. 13, pp. 1-12, Frontiers in Pharmacology, Lausanne, Switzerland, C1
Effects of psychotropic drugs on ribosomal genes and protein synthesis
Zoe Liu, Trang Truong, Chiara Bortolasci, Briana Spolding, Bruna Panizzutti, Courtney Swinton, Jee Kim, Srisaiyini Kidnapillai, Mark Richardson, Laura Gray, Olivia Dean, Sean McGee, Michael Berk, Ken Walder
(2022), Vol. 23, pp. 7180-7180, International Journal of Molecular Sciences, Basel, Switzerland, C1
N Travica, H Aslam, A O'Neil, M Lane, M Berk, E Gamage, K Walder, Z Liu, T Segasby, W Marx
(2022), Vol. 193, pp. 107656-107656, Neurobiology of Learning and Memory, United States, C1
Integrative analyses of transcriptomes to explore common molecular effects of antipsychotic drugs
Trang Truong, Chiara Bortolasci, Srisaiyini Kidnapillai, Briana Spolding, Bruna Panizzutti, Zoe Liu, Jee Kim, Olivia Dean, Mark Richardson, Michael Berk, Ken Walder
(2022), Vol. 23, pp. 7508-7508, International Journal of Molecular Sciences, Basel, Switzerland, C1
Repurposing Drugs via Network Analysis: Opportunities for Psychiatric Disorders
T Truong, B Panizzutti, J Kim, K Walder
(2022), Vol. 14, Pharmaceutics, Switzerland, C1
The role of metformin as a treatment for neuropsychiatric illness
S Dodd, L Sominsky, D Siskind, C Bortolasci, A Carvalho, M Maes, A Walker, K Walder, A Yung, L Williams, H Myles, T Watson, M Berk
(2022), Vol. 64, pp. 32-43, European Neuropsychopharmacology, Netherlands, C1
Kanika Mehta, Mohammadreza Mohebbi, Julie Pasco, Lana Williams, Ken Walder, Boon Ng, Veer Gupta
(2022), Vol. 12, pp. 17802-, Scientific Reports, England, C1
Effects of psychoactive drugs on cellular bioenergetic pathways
C Bortolasci, B Spolding, S Kidnapillai, M Richardson, N Vasilijevic, S Martin, L Gray, S McGee, M Berk, K Walder
(2021), Vol. 22, pp. 79-93, World Journal of Biological Psychiatry, England, C1
Y Quidé, C Bortolasci, B Spolding, S Kidnapillai, O Watkeys, S Cohen-Woods, V Carr, M Berk, K Walder, M Green
(2021), Vol. 105, Progress in Neuro-Psychopharmacology and Biological Psychiatry, England, C1
H Stokes, J Martens, M Jelocnik, K Walder, Y Segal, M Berg, A Bennett
(2021), Vol. 68, pp. 487-498, Transboundary and Emerging Diseases, Germany, C1
Preventing the development of severe COVID-19 by modifying immunothrombosis
G Morris, C Bortolasci, B Puri, L Olive, W Marx, A O'Neil, E Athan, A Carvalho, M Maes, K Walder, M Berk
(2021), Vol. 264, Life Sciences, Netherlands, C1
Diet and depression: exploring the biological mechanisms of action
W Marx, M Lane, M Hockey, H Aslam, M Berk, K Walder, A Borsini, J Firth, C Pariante, K Berding, J Cryan, G Clarke, J Craig, K Su, D Mischoulon, F Gomez-Pinilla, J Foster, P Cani, S Thuret, H Staudacher, A Sánchez-Villegas, H Arshad, T Akbaraly, A O’Neil, T Segasby, F Jacka
(2021), Vol. 26, pp. 134-150, Molecular Psychiatry, England, C1
Increasing Nrf2 Activity as a Treatment Approach in Neuropsychiatry
G Morris, A Walker, K Walder, M Berk, W Marx, A Carvalho, M Maes, B Puri
(2021), Vol. 58, pp. 2158-2182, Molecular Neurobiology, United States, C1
Gerwyn Morris, B Puri, C Bortolasci, Andre Carvalho, M Berk, K Walder, E Moreira, M Maes
(2021), Vol. 125, pp. 244-263, Neuroscience and biobehavioral reviews, Amsterdam, The Netherlands, C1
The endocannabinoid system and retinoic acid signaling combine to influence bone growth
D Fraher, R Mann, M Dubuisson, M Ellis, T Yu, K Walder, A Ward, C Winkler, Y Gibert
(2021), Vol. 529, Molecular and Cellular Endocrinology, Ireland, C1
G Morris, E Gamage, N Travica, M Berk, F Jacka, A O'Neil, B Puri, A Carvalho, C Bortolasci, K Walder, W Marx
(2021), Vol. 172, pp. 101-122, Free radical biology and medicine, Amsterdam, The Netherlands, C1
G Morris, C Bortolasci, B Puri, W Marx, A O'Neil, E Athan, K Walder, M Berk, L Olive, A Carvalho, M Maes
(2021), Vol. 144, Cytokine, England, C1
The lipid paradox in neuroprogressive disorders: causes and consequences
Gerwyn Morris, M Berk, K Walder, A O'Neil, M Maes, B Puri
(2021), Vol. 128, pp. 35-57, Neuroscience and biobehavioral reviews, Amsterdam, The Netherlands, C1
The endocannabinoidome in neuropsychiatry: Opportunities and potential risks
G Morris, K Walder, S Kloiber, P Amminger, M Berk, C Bortolasci, M Maes, B Puri, A Carvalho
(2021), Vol. 170, Pharmacological Research, Netherlands, C1
B Panizzutti, C Bortolasci, B Spolding, S Kidnapillai, T Connor, M Richardson, T Truong, Z Liu, G Morris, L Gray, J Kim, O Dean, M Berk, K Walder
(2021), Vol. 22, International Journal of Molecular Sciences, Switzerland, C1
R Kale, T Nguyen, J Price, N Yates, K Walder, M Berk, R Sillitoe, A Kouzani, S Tye
(2021), Vol. 15, Frontiers in Human Neuroscience, Switzerland, C1
C Bortolasci, A Turner, M Mohebbi, Z Liu, M Ashton, L Gray, W Marx, A Walker, G Kowalski, F Jacka, M Berk, O Dean, K Walder
(2021), Vol. 142, pp. 376-383, Journal of Psychiatric Research, England, C1
Biological mechanism(S) underpinning the association between antipsychotic drugs and weight gain
B Panizzutti, C Bortolasci, B Spolding, S Kidnapillai, T Connor, M Richardson, T Truong, Z Liu, L Gray, J Kim, O Dean, M Berk, K Walder
(2021), Vol. 10, Journal of Clinical Medicine, Switzerland, C1
J Martens, H Stokes, M Berg, K Walder, Y Segal, M Magrath, A Bennett
(2021), Vol. 121, pp. 333-339, Emu, C1
K Hasebe, M Mohebbi, L Gray, A Walker, C Bortolasci, A Turner, M Berk, K Walder, M Maes, B Kanchanatawan, M Ashton, L Berk, C Ng, G Malhi, A Singh, O Dean
(2021), Vol. 34, Acta Neuropsychiatrica, England, C1
The use of a gene expression signature and connectivity map to repurpose drugs for bipolar disorder
S Kidnapillai, C Bortolasci, M Udawela, B Panizzutti, B Spolding, T Connor, A Sanigorski, O Dean, T Crowley, S Jamain, L Gray, E Scarr, M Leboyer, B Dean, M Berk, K Walder
(2020), Vol. 21, pp. 775-783, World Journal of Biological Psychiatry, England, C1
S Kidnapillai, B Wade, C Bortolasci, B Panizzutti, B Spolding, T Connor, T Crowley, S Jamain, L Gray, M Leboyer, M Berk, K Walder
(2020), Vol. 34, pp. 370-379, Journal of Psychopharmacology, United States, C1
C Bortolasci, W Marx, A Walker, K Hasebe, B Kavanagh, M Morris, M Mohebbi, A Turner, L Gray, L Berk, K Walder, M Berk, O Dean
(2020), Vol. 10, pp. e035080-, BMJ open, England, C1
J Martens, H Stokes, M Berg, K Walder, A Bennett
(2020), Vol. 10, Scientific Reports, England, C1
J Martens, H Stokes, M Berg, K Walder, S Raidal, M Magrath, A Bennett
(2020), Vol. 2020, PeerJ, United States, C1
C Bortolasci, C Voigt, A Turner, M Mohebbi, L Gray, S Dodd, K Walder, M Berk, S Cotton, G Malhi, C Ng, N Dowling, J Sarris, O Dean
(2020), Vol. 32, pp. 313-320, Acta Neuropsychiatrica, England, C1
J Martens, H Stokes, M Berg, K Walder, S Raidal, M Magrath, A Bennett
(2020), Vol. 15, PLoS ONE, United States, C1
P Ajji, M Binder, K Walder, M Puri
(2020), Vol. 96, pp. 146-156, Process biochemistry, Amsterdam, The Netherlands, C1
The pathophysiology of SARS-CoV-2: A suggested model and therapeutic approach
G Morris, C Bortolasci, B Puri, L Olive, W Marx, A O'Neil, E Athan, A Carvalho, M Maes, K Walder, M Berk
(2020), Vol. 258, Life Sciences, Netherlands, C1
Can endolysosomal deacidification and inhibition of autophagy prevent severe COVID-19?
G Morris, E Athan, K Walder, C Bortolasci, A O'Neil, W Marx, M Berk, A Carvalho, M Maes, B Puri
(2020), Vol. 262, Life Sciences, Netherlands, C1
Endothelial dysfunction in neuroprogressive disorders-causes and suggested treatments
G Morris, B Puri, L Olive, A Carvalho, M Berk, K Walder, L Gustad, M Maes
(2020), Vol. 18, BMC Medicine, England, C1
Transcriptional effects of psychoactive drugs on genes involved in neurogenesis
C Bortolasci, B Spolding, S Kidnapillai, T Connor, T Truong, Z Liu, B Panizzutti, M Richardson, L Gray, M Berk, O Dean, K Walder
(2020), Vol. 21, pp. 1-19, International Journal of Molecular Sciences, Switzerland, C1
Species, sex and geographic variation in chlamydial prevalence in abundant wild Australian parrots
H Stokes, J Martens, K Walder, Y Segal, M Berg, A Bennett
(2020), Vol. 10, Scientific Reports, England, C1
Combination of Balsamin and Flavonoids Induce Apoptotic Effects in Liver and Breast Cancer Cells
P Ajji, K Walder, M Puri
(2020), Vol. 11, Frontiers in Pharmacology, Switzerland, C1
Y Quidé, C Bortolasci, B Spolding, S Kidnapillai, O Watkeys, S Cohen-Woods, M Berk, V Carr, K Walder, M Green
(2019), Vol. 49, pp. 2736-2744, Psychological Medicine, England, C1
Prevalence of BFDV in wild breeding Platycercus elegans
J Eastwood, M Berg, R Ribot, K Buchanan, K Walder, A Bennett
(2019), Vol. 160, pp. 557-565, Journal of Ornithology, C1
M Ashton, O Dean, A Walker, C Bortolasci, C Ng, M Hopwood, B Harvey, M Möller, J McGrath, W Marx, A Turner, S Dodd, J Scott, J Khoo, K Walder, J Sarris, M Berk
(2019), Vol. 10, Frontiers in Psychiatry, Switzerland, C1
Identification of Chlamydia gallinacea in a parrot and in free-range chickens in Australia
H Stokes, J Martens, A Chamings, K Walder, M Berg, Y Segal, A Bennett
(2019), Vol. 97, pp. 398-400, Australian veterinary journal, Chichester, Eng., C1
The compensatory antioxidant response system with a focus on neuroprogressive disorders
G Morris, B Puri, A Walker, M Berk, K Walder, C Bortolasci, W Marx, A Carvalho, M Maes
(2019), Vol. 95, Progress in Neuro-Psychopharmacology and Biological Psychiatry, England, C1
Johanne Martens, Helena Stokes, Justin Eastwood, Shane Raidal, Andrew Peters, Mathew Berg, Ken Walder, Michael Magrath, Andrew Bennett
(2019), Vol. 119, pp. 402-406, Emu - Austral ornithology, Abingdon, Eng., C1
Modulation of high fat diet-induced microbiome changes, but not behaviour, by minocycline
K Hasebe, L Rivera, C Smith, T Allnutt, T Crowley, T Nelson, O Dean, S McGee, K Walder, L Gray
(2019), Vol. 82, pp. 309-318, Brain, Behavior, and Immunity, Netherlands, C1
G Morris, B Puri, A Walker, M Maes, A Carvalho, K Walder, C Mazza, M Berk
(2019), Vol. 148, Pharmacological Research, Netherlands, C1
S Kidnapillai, C Bortolasci, B Panizzutti, B Spolding, T Connor, K Bonifacio, A Sanigorski, O Dean, T Crowley, S Jamain, L Gray, M Leboyer, M Berk, K Walder
(2019), Vol. 20, pp. 766-777, World Journal of Biological Psychiatry, London, Eng., C1
Shared pathways for neuroprogression and somatoprogression in neuropsychiatric disorders
G Morris, B Puri, A Walker, M Maes, A Carvalho, C Bortolasci, K Walder, M Berk
(2019), Vol. 107, pp. 862-882, Neuroscience and biobehavioral reviews, Amsterdam, The Netherlands, C1
S Cotton, M Berk, A Watson, S Wood, K Allott, C Bartholomeusz, C Bortolasci, K Walder, B O'Donoghue, O Dean, A Chanen, G Amminger, P McGorry, A Burnside, J Uren, A Ratheesh, S Dodd
(2019), Vol. 20, Trials, England, C1
The role of hypernitrosylation in the pathogenesis and pathophysiology of neuroprogressive diseases
G Morris, K Walder, A Carvalho, S Tye, K Lucas, M Berk, M Maes
(2018), Vol. 84, pp. 453-469, Neuroscience and Biobehavioral Reviews, United States, C1
Mechanisms underpinning the polypharmacy effects of medications in psychiatry
C Bortolasci, B Spolding, E Callaly, S Martin, B Panizzutti, S Kidnapillai, T Connor, K Hasebe, M Mohebbi, O Dean, S McGee, S Dodd, L Gray, M Berk, K Walder
(2018), Vol. 21, pp. 582-591, International Journal of Neuropsychopharmacology, England, C1
Parminder Ajji, Shailendra Sonkar, Ken Walder, Munish Puri
(2018), Vol. 114, pp. 226-234, International journal of biological macromolecules, Amsterdam, The Netherlands, C1
G Morris, B Puri, K Walder, M Berk, B Stubbs, M Maes, A Carvalho
(2018), Vol. 55, pp. 8765-8787, Molecular Neurobiology, United States, C1
J Price, Carrie Bronars, Sophie Erhardt, Kathyrn Cullen, Lilly Schwieler, Michael Berk, Ken Walder, Sean McGee, Mark Frye, Susannah Tye
(2018), Vol. 90, pp. 212-220, Neuroscience and biobehavioral reviews, Amsterdam, The Netherlands, C1
APP deficiency results in resistance to obesity but impairs glucose tolerance upon high fat feeding
J Czeczor, A Genders, K Aston-Mourney, T Connor, L Hall, K Hasebe, M Ellis, K De Jong, D Henstridge, P Meikle, M Febbraio, K Walder, S McGee
(2018), Vol. 237, pp. 311-322, Journal of Endocrinology, England, C1
G Morris, B Stubbs, C Köhler, K Walder, A Slyepchenko, M Berk, A Carvalho
(2018), Vol. 41, pp. 255-265, Sleep Medicine Reviews, England, C1
A Kaspi, I Khurana, M Ziemann, T Connor, B Spolding, P Zimmet, K Walder, A El-Osta
(2018), Vol. 62, Molecular Nutrition and Food Research, Germany, C1
Justin Eastwood, Mathew Berg, Raoul Ribot, Helena Stokes, Johanne Martens, Katherine Buchanan, Ken Walder, Andrew Bennett
(2018), Vol. 118, pp. 369-374, Emu: Austral ornithology, Abingdon, Eng., C1
B Panizzutti, C Bortolasci, K Hasebe, S Kidnapillai, L Gray, K Walder, M Berk, M Mohebbi, S Dodd, C Gama, P Magalhães, S Cotton, F Kapczinski, A Bush, G Malhi, O Dean
(2018), Vol. 30, pp. 334-341, Acta Neuropsychiatrica, England, C1
Psammomys obesus: a Natural Diet-Controlled Model for Diabetes and Cardiovascular Diseases
R Chaudhary, K Walder, C Hagemeyer, J Kanwar
(2018), Vol. 20, Current Atherosclerosis Reports, United States, C1
G Morris, M Berk, H Klein, K Walder, P Galecki, M Maes
(2017), Vol. 54, pp. 4271-4291, Molecular Neurobiology, United States, C1
G Morris, M Berk, A Carvalho, J Caso, Y Sanz, K Walder, M Maes
(2017), Vol. 54, pp. 4432-4451, Molecular Neurobiology, United States, C1
Gene expression signature: A powerful approach for drug discovery in diabetes
S Sithara, T Crowley, K Walder, K Aston-Mourney
(2017), Vol. 232, pp. R131-R139, Journal of Endocrinology, England, C1
A model of the mitochondrial basis of bipolar disorder
G Morris, K Walder, S McGee, O Dean, S Tye, M Maes, M Berk
(2017), Vol. 74, pp. 1-20, Neuroscience and Biobehavioral Reviews, United States, C1
Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice
V Gaur, T Connor, K Venardos, D Henstridge, S Martin, C Swinton, S Morrison, K Aston-Mourney, S Gehrig, R van Ewijk, G Lynch, M Febbraio, G Steinberg, M Hargreaves, K Walder, S McGee
(2017), Vol. 19, pp. 936-943, Diabetes, Obesity and Metabolism, England, C1
S Bond, K Howlett, G Kowalski, S Mason, T Connor, A Cooper, V Streltsov, C Bruce, K Walder, S McGee
(2017), Vol. 31, pp. 2592-2602, FASEB journal, Bethesda, Md., C1
K Hasebe, L Gray, C Bortolasci, B Panizzutti, M Mohebbi, S Kidnapillai, B Spolding, K Walder, M Berk, G Malhi, S Dodd, O Dean
(2017), Vol. 29, pp. 337-346, Acta Neuropsychiatrica, England, C1
Exercise and the skeletal muscle epigenome
S McGee, K Walder
(2017), Vol. 7, Cold Spring Harbor Perspectives in Medicine, United States, C1
Balsamin induces apoptosis in breast cancer cells via DNA fragmentation and cell cycle arrest
P Ajji, M Binder, K Walder, M Puri
(2017), Vol. 432, pp. 189-198, Molecular and Cellular Biochemistry, Netherlands, C1
A Kouzani, R Kale, P Zarate-Garza, M Berk, K Walder, S Tye
(2017), Vol. 25, pp. 1365-1374, IEEE Transactions on Neural Systems and Rehabilitation Engineering, United States, C1
I Khurana, A Kaspi, M Ziemann, T Block, T Connor, B Spolding, A Cooper, P Zimmet, A El-Osta, K Walder
(2017), Vol. 49, pp. S103-S104, Pathology, Amsterdam, The Netherlands, C1
G Morris, M Berk, P Galecki, K Walder, M Maes
(2016), Vol. 53, pp. 1195-1219, Molecular Neurobiology, United States, C1
G Morris, M Berk, K Walder, M Maes
(2016), Vol. 53, pp. 2550-2571, Molecular Neurobiology, United States, C1
G Morris, K Walder, B Puri, M Berk, M Maes
(2016), Vol. 53, pp. 4638-4658, Molecular neurobiology, New York, N.Y., C1
Citalopram and sertraline exposure compromises embryonic bone development
D Fraher, J Hodge, F Collier, J McMillan, R Kennedy, M Ellis, G Nicholson, K Walder, S Dodd, M Berk, J Pasco, L Williams, Y Gibert
(2016), Vol. 21, pp. 656-664, Molecular Psychiatry, England, C1
Engineered atherosclerosis-specific zinc ferrite nanocomplex-based MRI contrast agents
R Chaudhary, K Roy, R Kanwar, K Walder, J Kanwar
(2016), Vol. 14, Journal of Nanobiotechnology, England, C1
M Coughlan, G Higgins, T Nguyen, S Penfold, V Thallas-Bonke, S Tan, G Ramm, N Van Bergen, D Henstridge, K Sourris, B Harcourt, I Trounce, P Robb, A Laskowski, S McGee, A Genders, K Walder, B Drew, P Gregorevic, H Qian, M Thomas, G Jerums, R Macisaac, A Skene, D Power, E Ekinci, X Wijeyeratne, L Gallo, M Herman-Edelstein, M Ryan, M Cooper, D Thorburn, J Forbes
(2016), Vol. 65, pp. 1085-1098, Diabetes, United States, C1
I Khurana, A Kaspi, M Ziemann, T Block, T Connor, B Spolding, A Cooper, P Zimmet, A El-Osta, K Walder
(2016), Vol. 40, pp. 1079-1088, International Journal of Obesity, England, C1
P Ajji, K Walder, M Puri
(2016), Vol. 71, pp. 265-271, Plant foods for human nutrition, New York, N.Y., C1
Y Kim, S McGee, J Czeczor, A Walker, R Kale, A Kouzani, K Walder, M Berk, S Tye
(2016), Vol. 6, pp. e842-, Translational psychiatry, United States, C1
V Gaur, T Connor, A Sanigorski, S Martin, C Bruce, D Henstridge, S Bond, K McEwen, L Kerr-Bayles, T Ashton, C Fleming, M Wu, L Pike Winer, D Chen, G Hudson, J Schwabe, K Baar, M Febbraio, P Gregorevic, F Pfeffer, K Walder, M Hargreaves, S McGee
(2016), Vol. 16, pp. 2802-2810, Cell Reports, United States, C1
B Hayward, J Molero, K Windmill, A Sanigorski, J Weir, N McRae, K Aston-Mourney, B Osborne, B Liao, K Walder, P Meikle, N Konstantopoulos, C Schmitz-Peiffer
(2016), Vol. 124, pp. 602-612, Experimental and Clinical Endocrinology and Diabetes, Germany, C1
Leptin's metabolic and immune functions can be uncoupled at the ligand/receptor interaction level.
L Zabeau, C Jensen, S Seeuws, K Venken, A Verhee, D Catteeuw, G van Loo, H Chen, K Walder, J Hollis, S Foote, M Morris, J Van der Heyden, F Peelman, B Oldfield, J Rubio, D Elewaut, J Tavernier
(2015), Vol. 72, pp. 629-644, Cellular and Molecular Life Sciences, Switzerland, C1
Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses
G Morris, M Berk, K Walder, M Maes
(2015), Vol. 13, pp. 1-23, BMC Medicine, London, Eng., C1
Mitochondrial dysfunction in the pathophysiology of bipolar disorder: effects of pharmacotherapy
E Callaly, K Walder, G Morris, M Maes, M Debnath, M Berk
(2015), Vol. 15, pp. 355-365, Mini-reviews in medicinal chemistry, Amsterdam, The Netherlands, C1
J Eastwood, M Berg, B Spolding, K Buchanan, A Bennett, K Walder
(2015), Vol. 63, pp. 1-8, Australian journal of zoology, Clayton, Vic., C1
Evolution of optogenetic microdevices
R Kale, A Kouzani, K Walder, M Berk, S Tye
(2015), Vol. 2, pp. 1-11, Neurophotonics, Bellingham, W.A., C1
D Fraher, M Ellis, S Morrison, S McGee, A Ward, K Walder, Y Gibert
(2015), Vol. 156, pp. 3596-3609, Endocrinology, Bethesda, Md., C1
CXCR4 Antagonism attenuates the development of diabetic cardiac fibrosis
P Chu, K Walder, D Horlock, D Williams, E Nelson, M Byrne, K Jandeleit-Dahm, P Zimmet, D Kaye
(2015), Vol. 10, pp. 1-13, PLoS One, San Francisco, CA, C1
Wireless optogenetics: an exploration of portable microdevices for small animal photostimulation
R Kale, A Kouzani, M Berk, K Walder, J Berk, S Tye
(2015), Vol. 20, pp. 225-230, Procedia technology, Amsterdam, The Netherlands, C1
Rapid development of non-alcoholic steatohepatitis in Psammomys obesus (Israeli Sand Rat)
B Spolding, T Connor, C Wittmer, L Abreu, A Kaspi, M Ziemann, G Kaur, A Cooper, S Morrison, S Lee, A Sinclair, Y Gibert, J Trevaskis, J Roth, A El-Osta, R Standish, K Walder
(2014), Vol. 9, pp. 1-7, PLoS one, San Francisco, Calif., C1
Phylogenetic analysis of beak and feather disease virus across a host ring-species complex
J Eastwood, M Berg, R Ribot, S Raidal, K Buchanan, K Walder, A Bennett
(2014), Vol. 111, pp. 14153-14158, Proceedings of the national scademy of sciences of the USA, Washington, DC, C1
R Simpson, G Nicholson, J Proietto, A Sarah, K Sanders, G Phillips, J Chambers, R MacGinley, N Orford, K Walder, G Krippner, K Skoff, V Wacher
(2014), Vol. 37, pp. 3121-3123, Diabetes Care, Alexandria VA., C1
Non-referenced genome assembly from epigenomic short-read data
A Kaspi, M Ziemann, S Keating, I Khurana, T Connor, B Spolding, A Cooper, R Lazarus, K Walder, P Zimmet, A El-Osta
(2014), Vol. 9, pp. 1329-1338, Epigenetics, United States, C1
Genetic variation associated with hypersensitivity to mercury.
D Austin, B Spolding, S Gondalia, K Shandley, E Palombo, S Knowles, K Walder
(2014), Vol. 21, pp. 236-241, Toxicology International, India, C1-1
H Kulkarni, H Goring, J Curran, V Diego, T Dyer, S Cole, K Walder, G Collier, J Blangero, M Carless
(2013), Vol. 71, pp. 1095-1100, Cancer chemotherapy and pharmacology, Heidelberg, Germany, C1
A Walker, S Burnett, K Hasebe, J McGillivray, L Gray, S McGee, K Walder, M Berk, S Tye
(2013), Vol. 242, pp. 76-83, Behavioural brain research, Amsterdam, The Netherlands, C1
S Gurudevan, R Kanwar, R Veedu, S Sasidharan, R Kennedy, K Walder, N Prasad, J Kanwar
(2013), Vol. 13, pp. 322-334, Current gene therapy, Bussum, The Netherlands, C1
K Bolton, D Segal, K Walder
(2012), Vol. 6, pp. 67-72, Biologics : targets and therapy, Auckland, New Zealand, C1
Methazolamide is a new hepatic insulin sensitizer that lowers blood glucose in vivo
N Konstantopoulos, J Molero, S McGee, B Spolding, T Connor, M de Vries, S Wanyonyi, R Fahey, S Morrison, C Swinton, S Jones, A Cooper, L Garcia-Guerra, V Foletta, G Krippner, S Andrikopoulos, K Walder
(2012), Vol. 61, pp. 2146-2154, Diabetes, Alexandria, Va., C1
H Kulkarni, H Goring, V Diego, S Cole, K Walder, G Collier, J Blangero, M Carless
(2012), Vol. 5, pp. 1-12, BMC medical genomics, London, England, C1
N Cummings, K Shields, J Curran, K Bozaoglu, J Trevaskis, K Gluschenko, G Cai, A Comuzzie, T Dyer, K Walder, P Zimmet, G Collier, J Blangero, J Jowett
(2012), Vol. 36, pp. 201-206, International journal of obesity, London, England, C1
Design of a miniature UHF PIFA for DBS implants
M Hosain, A Kouzani, S Tye, K Walder, L Kong
(2012), pp. 485-489, CME 2012 : Proceedings of the 2012 IEEE/ICME International Conference on Complex Medical Engineering, Kobe, Japan, E1
A head mountable deep brain stimulation device for laboratory animals
A Kouzani, S Tye, K Walder, L Kong
(2011), pp. 275-280, Advances in computer, communication, control and automation, Berlin, Germany, B1
A gene expression signature for insulin resistance
N Konstantopoulos, V Foletta, D Segal, K Shields, A Sanigorski, K Windmill, C Swinton, T Connor, S Wanyonyi, T Dyer, R Fahey, R Watt, J Curran, J Molero, G Krippner, G Collier, D James, J Blangero, J Jowett, K Walder
(2011), Vol. 43, pp. 110-120, Physiological genomics, Bethesda, Md., C1
Deficiency in interferon-y results in reduced body weight and better glucose tolerance in mice
N Wong, B Fam, G Cempako, G Steinberg, K Walder, T Kay, J Proietto, S Andrikopoulos
(2011), Vol. 152, pp. 3690-3699, Endocrinology, Chevy Chase, Md., C1
Effects of rosiglitazone on intramyocellular lipid accumulation in Psammomys obesus
J Molero, S Lee, I Leizerman, A Chajut, A Cooper, K Walder
(2010), Vol. 1802, pp. 235-239, B B A - Molecular Basis of Disease, Amsterdam, The Netherlands, C1
Genetic variation in PARL influences mitochondrian content
J Curran, J Jowett, L Abraham, L Diepeveen, K Elliott, T Dyer, L Kerr-Bayles, M Johnson, A Comuzzie, E Moses, K Walder, G Collier, J Blangero, A Kissebah
(2010), Vol. 127, pp. 183-190, Human genetics, Heidelberg, Germany, C1
M Prior, V Foletta, J Jowett, D Segal, M Carless, J Curran, T Dyer, E Moses, A McAinch, N Konstantopoulos, K Bozaoglu, G Collier, D Cameron-Smith, J Blangero, K Walder
(2010), Vol. 59, pp. 1057-1064, Metabolism, Philadelphia, Pa., C1
Chemerin, a novel adipokine in the regulation of angiogenesis
K Bozaoglu, J Curran, C Stocker, M Zaibi, D Segal, N Konstantopoulos, S Morrison, M Carless, T Dyer, S Cole, H Goring, E Moses, K Walder, M Cawthorne, J Blangero, J Jowett
(2010), Vol. 95, pp. 2476-2485, Journal of clinical endocrinology & metabolism, Chevy Chase, Md., C1
A Civitarese, P MacLean, S Carling, L Kerr-Bayles, R McMillan, A Pierce, T Becker, C Moro, J Finlayson, N Lefort, C Newgard, L Mandarino, W Cefalu, K Walder, G Collier, M Hulver, S Smith, E Ravussin
(2010), Vol. 11, pp. 412-426, Cell metabolism, Cambridge, Mass., C1
NDRG2, a novel regulator of myoblast proliferation, is regulated by anabolic and catabolic factors
V Foletta, M Prior, N Stupka, K Carey, D Segal, S Jones, C Swinton, S Martin, D Cameron-Smith, K Walder
(2009), Vol. 587, pp. 1619-1634, Journal of physiology, Oxford, England, C1
F Collier, A Loving, A Baker, J McLeod, K Walder, M Kirkland
(2009), Vol. 2, pp. 9-23, Journal of cell death, Auckland, New Zealand, C1
Identification of secreted proteins associated with obesity and type 2 diabetes in Psammomys obesus
K Bolton, D Segal, J McMillan, A Sanigorski, G Collier, K Walder
(2009), Vol. 33, pp. 1-13, International journal of obesity, Hampshire, England, C1
Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity
H Su, J Gunter, M de Vries, T Connor, S Wanyonyi, F Newell, D Segal, J Molero, O Reizes, J Prins, L Hutley, K Walder, J Whitehead
(2009), Vol. 386, pp. 351-355, Biochemical and biophysical research communications, San Diego, Calif., C1
Chemerin is associated with metabolic syndrome phenotypes in a Mexican-American population
K Bozaoglu, D Segal, K Shields, N Cummings, J Curran, A Comuzzie, M Mahaney, D Rainwater, J VandeBerg, J MacCluer, G Collier, J Blangero, K Walder, J Jowett
(2009), Vol. 94, pp. 3085-3088, The Journal of Clinical Endocrinology & Metabolism, Philadelphia, PA, C1
S Martin, F Collier, M Kirkland, K Walder, N Stupka
(2009), Vol. 61, pp. 93-107, Cytotechnology: international journal of cell culture and biotechnology, Dordrecht, Netherlands, C1
Decorin is a secreted protein associated with obesity and type 2 diabetes
K Bolton, D Segal, J McMillan, J Jowett, L Heilbronn, K Abberton, P Zimmet, D Chisholm, G Collier, K Walder
(2008), Vol. 32, pp. 1113-1121, International journal of obesity, London, England, C1-1
Chemerin is a novel adipokine associated with obesity and metabolic syndrome
K Bozaoglu, K Bolton, J McMillan, P Zimmet, J Jowett, G Collier, K Walder, D Segal
(2007), Vol. 148, pp. 4687-4694, Endocrinology, Los Angeles, Calif., C1
Localization and expression of selenoprotein S in the testis of Psammomys obesus
K Windmill, J Tenne-Brown, R Bayles, J Trevaskis, Y Gao, K Walder
(2007), Vol. 38, pp. 97-101, Journal of molecular histology, Amsterdam, The Netherlands, C1
SEPS1 protects RAW264.7 cells from pharmacological ER stress agent-induced apoptosis
K Kim, Y Gao, K Walder, G Collier, J Skelton, A Kissebah
(2007), Vol. 354, pp. 127-132, Biochemical and biophysical research communications, Orlando, Fla., C1
Secretion of the glucose-regulated selenoprotein SEPS1 from hepatoma cells
Y Gao, J Pagnon, H Feng, N Konstantopoulos, J Jowett, K Walder
(2007), Vol. 356, pp. 636-641, Biochemical and biophysical research communications, Orlando, Fla., C1
K Carey, D Segal, R Klein, A Sanigorski, K Walder, G Collier, D Cameron-Smith
(2006), Vol. 56, pp. 246-255, Pathology international, Carlton South, Vic, C1
Activation of the selenopritein SEPS1 gene expression by pro-inflammatory cytokines in Hep G2 cells
Y Gao, N Hannan, S Wanyonyi, N Konstantopoulos, J Pagnon, H Feng, J Jowett, K Kim, K Walder, G Collier
(2006), Vol. 33, pp. 246-251, Cytokine, Amsterdam, The Netherlands, C1
Association of genetic vatiation within UBL5 with phenotypes of metabolic syndrome
K Bozaoglu, J Curran, K Elliott, K Walder, T Dyer, D Rainwater, J Vandenberg, A Comuzzie, G Collier, P Zimmet, J Maccluer, J Jowett, J Blangero
(2006), Vol. 78, pp. 147-159, Human biology, Detroit, Mich., C1
The mitochondrial rhomboid protease PSARL is a new candidate gene for type 2 diabetes
K Walder, L Kerr-Bayles, A Civitarese, J Jowett, J Curran, K Elliott, J Trevaskis, N Bishara, P Zimmet, L Mandarino, E Ravussin, J Blangero, A Kissebah, G Collier
(2005), Vol. 48, pp. 459-468, Diabetologia, Berlin , Germany, C1
Genetic variation in selenoprotein S influences inflammatory response
J Curran, J Jowett, K Elliott, Y Gao, K Gluschenko, W Jianmin, D Azim, G Cai, M Mahaney, A Comuzzie, T Dyer, K Walder, P Zimmet, J MacCluer, G Collier, A Kissebah, J Blangero
(2005), Vol. 37, pp. 1234-1241, Nature genetics, New York, N.Y., C1-1
J Trevaskis, K Walder, V Foletta, L Kerr-Bayles, J McMillan, A Cooper
(2005), Vol. 146, pp. 3757-3764, Endocrinology, Philadelphia, Pa., C1-1
R Southgate, C Bruce, A Carey, G Steinberg, K Walder, R Monks, M Watt, J Hawley, M Birnbaum, M Febbraio
(2005), Vol. 19, pp. 2072-2074, The FASEB journal : official publication of the Federation of American Societies for experimental biology, Bethesda, Md., C1-1
Identification and characterization of a lymphocytic Rho-GTPase effector: rhotekin-2
F Collier, C Gregorio-King, T Gough, C Talbot, K Walder, M Kirkland
(2004), Vol. 324, pp. 1360-1369, Biochemical and biophysical research communications, San Diego, Calif., C1
J Trevaskis, J McMillan, K Windmill, K Walder, G Collier
(2004), Vol. 137, pp. 65-73, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, Tarrytown, N.Y., C1
Y Gao, H Feng, K Walder, K Bolton, T Sunderland, N Bishara, M Quick, L Kantham, G Collier
(2004), Vol. 563, pp. 185-190, FEBS letters, Amsterdam, Netherlands, C1
J Molero, T Jensen, P Withers, M Couzens, H Herzog, C Thien, W Langdon, K Walder, M Murphy, D Bowtell, D James, G Cooney
(2004), Vol. 114, pp. 1326-1333, Journal of clinical investigation, New York, N.Y., C1
J Jowett, K Elliott, J Curran, N Hunt, K Walder, G Collier, P Zimmet, J Blangero
(2004), Vol. 53, pp. 2467-2472, Diabetes, Alexandria, Va., C1
Obesity and diabetes gene discovery approaches
K Walder, D Segal, J Jowett, J Blangero, G Collier
(2003), Vol. 9, pp. 1357-1372, Current pharmaceutical design, Schiphol, Netherlands, C1
Genetic studies in Psammomys obesus
K Walder, D Segal, J Jowett, J Blangero, P Zimmet, G Collier
(2003), Vol. 9, pp. 275-278, Progress in obesity research, Eastleigh, England, C1
Transcriptional profiling and gene discovery
G Collier, A De Silva, J Tenne-Brown, A Sanigorski, D Segal, L Kantham, K Walder
(2003), Vol. 9, pp. 36-39, Progress in obesity research, London, England, C1
Elevation in tanis expression alters glucose metabolism and insulin sensitivity in H4IIE cells
Y Gao, K Walder, T Sunderland, L Kantham, H Feng, M Quick, N Bishara, A De Silva, G Augert, J Tenne-Brown, G Collier
(2003), Vol. 52, pp. 929-934, Diabetes, New York, N.Y., C1
The taq IA and Ser311Cys polymorphisms in the dopamine D2 receptor gene and obesity
A Southon, K Walder, A Sanigorski, P Zimmet, G Nicholson, M Kotowicz, G Collier
(2003), Vol. 16, pp. 72-76, Diabetes, nutrition & metabolism, Milano, Italy, C1
Beacon interacts with cdc2/cdc28-like kinases
L Kantham, L Kerr-Bayles, N Godde, M Quick, R Webb, T Sunderland, J Bond, K Walder, G Augert, G Collier
(2003), Vol. 304, pp. 125-129, Biochemical and biophysical research communications, New York, N.Y., C1
ORP3 splice variants and their expression in human tissues and hematopoietic cells
F Collier, C Gregorio-King, J Apostolopoulos, K Walder, M Kirkland
(2003), Vol. 22, pp. 1-9, DNA and cell biology, New Rochelle, N.Y., C1-1
Which genes are important in the development of type 2 diabetes?
G Collier, K Walder, A De Silva, S Morgan, D Segal, L Kantham, G Augert
(2002), pp. 175-186, Insulin resistance and insulin resistance syndrome, London, England, B1
Tanis: a link between type 2 diabetes and inflammation?
K Walder, L Kantham, J McMillan, J Trevaskis, L Kerr, A de Silva, T Sunderland, N Godde, Y Gao, N Bishara, K Windmill, J Tenne-Brown, G Augert, P Zimmet, G Collier
(2002), Vol. 51, pp. 1859-1866, Diabetes, New York, N.Y., C1
K Walder, E Ziv, R Kalman, K Whitecross, E Shafrir, P Zimmet, G Collier
(2002), Vol. 26, pp. 605-609, International journal of obesity, London, England, C1
K Walder, J McMillan, N Lapsys, A Kriketos, J Trevaskis, A Civitarese, A Southon, P Zimmet, G Collier
(2002), Vol. 26, pp. 442-449, International journal of obesity, London, England, C1
New approaches to gene discovery with animal models of obesity and diabetes
G Collier, K Walder, A De Silva, J Tenne-Brown, A Sanigorski, D Segal, L Kantham, G Augert
(2002), Vol. 967, pp. 403-413, Annals of the New York academy of science, New York, N.Y., C1
A custom-built insulin resistance gene chip
K Walder, D Segal, S Chehab, G Augert, D Cameron-Smith, M Hargreaves, G Collier
(2002), Vol. 967, pp. 274-282, Annals of the New York Academy of Sciences, New York, N.Y., C1
K Walder, J McMillan, S Lee, A Civitarese, P Zimmet, G Collier
(2001), Vol. 25, pp. 1281-1285, International journal of obesity, London, England, C1
Genetic variation and obesity in Australian women: A prospective study.
A De Silva, K Walder, E Boyko, K Whitecross, G Nicholson, M Kolowitz, J Pasco, G Collier
(2001), Vol. 9, pp. 733-740, Obesity, Silver Spring, Md., C1
AFLP fingerprinting of the human genome
M Prochazka, K Walder, J Xia
(2001), Vol. 108, pp. 59-65, Human genetics, Berlin, Germany, C1-1
Impact of obesity and leptin treatment on adipocyte gene expression in Psammomys obesus
A Sanigorski, D Cameron-Smith, P Lewandowski, K Walder, A de Silva, G Morton, G Collier
(2000), Vol. 164, pp. 45-50, Journal of endocrinology, Bristol, England, C1-1
Beacon: a novel gene involved in the regulation of energy balance
G Collier, J McMillan, K Windmill, K Walder, J Tenne-Brown, A de Silva, J Trevaskis, S Jones, G Morton, S Lee, G Augert, A Civitarese, P Zimmet
(2000), Vol. 49, pp. 1766-1771, Diabetes, Arlington, Va., C1-1
Leptin and the treatment of obesity
K Walder, A De Silva
(2000), Vol. 51, pp. 66-79, Drug Development Research, Hoboken, N.J., C1-1
K Walder, P Lewandowski, G Morton, A Sanigorski, A de Silva, P Zimmet, G Collier
(1999), Vol. 23, pp. 83-89, International journal of obesity, London, England, C1-1
K Walder, S Lee, P Zimmet, G Collier
(1998), Vol. 47, pp. 125-128, Metabolism, Amsterdam, The Netherlands, C1-1
K Walder, R Norman, R Hanson, P Schrauwen, M Neverova, C Jenkinson, J Easlick, C Warden, C Pecqueur, S Raimbault, D Ricquier, M Harper, K Silver, A Shuldiner, G Solanes, B Lowell, W Chung, R Leibel, R Pratley, E Ravussin
(1998), Vol. 7, pp. 1431-1435, Human molecular genetics, London, Eng., C1-1
Leptin and the development of obesity and diabetes in Psammomys obesus
G Collier, K Walder, P Lewandowski, A Sanigorski, P Zimmet
(1997), Vol. 5, pp. 455-458, Obesity research, Silver Spring, Md., C1-1
P Lewandowski, D Cameron-Smith, K Moulton, K Walder, A Sanigorski, G Collier
(1997), Vol. 827, pp. 536-540, Annals of the New York academy of sciences, Hoboken, N. J., C1-1
K Walder, C Dascaliuc, P Lewandowski, A Sanigorski, P Zimmet, G Collier
(1997), Vol. 5, pp. 193-200, Obesity research, London, England, C1-1
G Collier, A De Silva, A Sanigorski, K Walder, A Yamamoto, P Zimmet
(1997), Vol. 827, pp. 50-63, Annals of the New York Academy of Sciences, Chichester, Eng., C1-1
Ob (obese) gene expression and leptin levels in Psammomys obesus
K Walder, M Willet, P Zimmet, G Collier
(1997), Vol. 1354, pp. 272-278, Biochimica et biophysica acts, Amsterdam, The Netherlands, C1-1
G Collier, F Collier, A Sanigorski, K Walder, D Cameron-Smith, A Sinclair
(1997), Vol. 32, pp. 317-322, Lipids, Berlin, Germany, C1-1
Effect of coingestion of fat and protein with carbohydrate feedings on muscle glycogen storage
L Burke, G Collier, S Beasley, P Davis, P Fricker, P Heeley, K Walder, M Hargreaves
(1995), Vol. 78, pp. 2187-2192, Journal of applied physiology, Bethesda, Md., C1-1
Funded Projects at Deakin
Australian Competitive Grants
Characterisation of chemerin as a novel adipokine associated with obesity and metabolic syndrome
Prof Ken Walder, Dr Jeremy Jowett
DART Grant - Research - Diabetes Australia - Victoria (Research Trust)
- 2008: $22,274
- 2007: $22,274
Enzymatic synthesis, microencapsulation and biological evaluation of a new class of omega-3 derived functional food ingredients
Prof Colin Barrow, Prof Ken Walder, Dr Jaroslav Kralovec, Dr Jacqui Adcock, Prof Leigh Ackland, Dr Ian Musgrave, Dr Wei Zhang
ARC Linkage - Projects Rnd 1, ARC_DUAPAI ARC_Deakin University Australian Postgraduate Award Industry
- 2013: $14,921
- 2012: $183,043
- 2011: $159,949
- 2010: $153,111
Antidiabetic effects of a new secreted protein associated with type 2 diabetes
Prof Ken Walder
DART Grant - Research - Diabetes Australia - Victoria (Research Trust)
- 2009: $26,054
- 2008: $26,054
Discovery and development of novel insulin sensitising compounds for the treatment of Type 2 diabetes
Prof Ken Walder, A/Prof Fred Pfeffer, Dr Nicky Konstantopoulos, Dr Guy Krippner
ARC Linkage - Projects Rnd 1
- 2012: $139,973
- 2011: $88,130
- 2010: $86,763
The role of amyloid beta in insulin resistance
Prof Sean Mcgee, Prof Ken Walder, Prof Mark Hargreaves
NHMRC Project Grant
- 2014: $125,826
- 2013: $138,472
- 2012: $136,023
Understanding the role of class IIa histone deacetylases in metabolic disease
Prof Sean Mcgee, Prof Ken Walder
NHMRC Project Grant
- 2014: $164,086
- 2013: $161,714
- 2012: $143,600
Threats of avian pathogens to endangered parrots and human health: developing and utilizing tools for risk reduction
Prof Andy Bennett, A/Prof Shane Raidal, Prof Marcel Klaassen, Prof Kate Buchanan, Prof Ken Walder, Dr Michael Magrath, Dr Yonatan Segal, Prof Martyn Jeggo
ARC Linkage - Projects
- 2017: $54,016
- 2016: $105,523
- 2015: $112,909
- 2014: $60,397
Gene Expression Signature Technology to Repurpose Drugs for Bipolar Disorder
Prof Ken Walder, Prof Michael Berk, Prof Marion Leboyer, Prof Brian Dean
NHMRC Project Grant
- 2017: $157,493
- 2016: $207,762
- 2015: $117,544
The role of GAPDH acetylation and HDAC6 in liver metabolism and type 2 diabetes
Prof Sean Mcgee, Prof Clinton Bruce, Prof Forest White, Prof Ken Walder
NHMRC Project Grant
- 2020: $10,462
- 2019: $187,097
- 2018: $181,879
- 2017: $169,227
CREDIT: The CRE for the Development of Innovative Therapies for Psychiatric Disorders
Prof Michael Berk, Prof John McGrath, Prof Patrick McGorry, Prof John McNeil, Prof Gin Malhi, Prof Felice Jacka, A/Prof Susan Cotton, Prof Ken Walder, A/Prof Olivia Dean, Prof Lana Williams
NHMRC - Centres of Research Excellence
- 2023: $113,031
- 2022: $498,725
- 2021: $563,659
- 2020: $576,585
- 2019: $510,344
Using 'omics to unravel the pathophysiology and repurpose drugs to treat ME/CFS
Prof Ken Walder, Prof Michael Berk, Dr Chiara Bortolasci, Prof Sean Mcgee, Prof Clinton Bruce, Dr Wolf Marx
NHMRC Targeted Call for Research into Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) Grant Opportunity
- 2023: $70,390
- 2022: $164,314
- 2021: $152,361
- 2020: $25,320
Other Public Sector Funding
Global Gene Expression Analysis of 10 rat colon tissue samples
Prof Ken Walder
DPI Grant - Research - Department of Primary Industries - Victoria
- 2009: $16,666
Tissue distribution of RIPTAC in mice.
Prof Ken Walder
DPI Primary Industries Research Victoria
- 2010: $18,000
Determination of RIPTAC bioavailability, pharmacokinetics and distribution
Prof Ken Walder, Mr Timothy Connor, Ms Briana Randall
DPI Grant - Research - Department of Primary Industries - Victoria
- 2011: $12,000
Delivery of MIRNA Using Genetically Modified Influenza Virus
Prof John Stambas, Prof Alister Ward, Prof Ken Walder, Ms Yingju Xia
Victorian International Research Scholarships
- 2014: $60,000
Threats of avian pathogens to endangered parrots and human health: developing and utilizing tools for risk reduction
Prof Andy Bennett, A/Prof Shane Raidal, Prof Marcel Klaassen, Prof Kate Buchanan, Prof Ken Walder, Dr Michael Magrath, Dr Yonatan Segal, Prof Martyn Jeggo
Victorian Department of Economic Development, Jobs, Transport and Resources, Zoos Victoria
- 2017: $25,000
- 2016: $25,000
- 2015: $30,000
Fluorescent Cell Imager
Prof Ken Walder
NHMRC - Equipment Grant (pre 2017)
- 2014: $18,900
NHMRC Equipment Grant 2016
Prof Michael Berk, Prof Ken Walder
NHMRC - Equipment Grant (pre 2017)
- 2016: $17,691
The miRNA-mRNA integration of GenieUs multi-omics aberration platform for amyotrophic lateral sclerosis.
Prof Ken Walder, Ms Thi Thuy Trang Truong
International Education Resilience Fund
- 2022: $15,000
Industry and Other Funding
Positional Candidate Genes Affecting Metabolic Syndrome
Dr Ahmed Kissebah, Prof Ken Walder
NIH Contract - National Institutes of Health
- 2008: $83,444
- 2007: $123,502
- 2006: $96,944
Anti-inflammatory activity of mussel oil
Prof Ken Walder
McFarlane Marketing Grant - Research
- 2009: $4,700
Enzymatic synthesis, microencapsulation and biological evaluation of a new class of omega-3 derived functional food ingredients
Prof Colin Barrow, Prof Ken Walder, Dr Jaroslav Kralovec, Dr Jacqui Adcock, Prof Leigh Ackland, Dr Ian Musgrave, Dr Wei Zhang
Ocean Nutrition Canada Ltd
- 2012: $70,607
- 2011: $53,835
- 2010: $52,910
Novel Therapies for the Treatment of Obesity
Prof Ken Walder
ChemGenex Contract Research
- 2008: $2,133,334
- 2007: $2,400,000
- 2006: $2,420,000
Mechanism of action of VVP808
Prof Ken Walder
Verva Grant - Research - Verva Pharmaceuticals Limited
- 2010: $17,740
- 2009: $180,000
Effects of novel insulin formulations on glucose homeostasis in streptozotocin-treated diabetic rats
Prof Ken Walder
VHS Grant - Research - VITAL HEALTH SCIENCES PTY LTD
- 2009: $72,500
- 2008: $72,500
Discovery and development of novel insulin sensitising compounds for the treatment of Type 2 diabetes
Prof Ken Walder, A/Prof Fred Pfeffer, Dr Nicky Konstantopoulos, Dr Guy Krippner
Verva Pharmaceuticals Ltd
- 2012: $127,200
- 2011: $174,725
- 2010: $146,043
Development of a rat model of acute pancreatitis
Prof Ken Walder
Xenome Grant - Research
- 2009: $80,000
Expression of Galanin receptors in Mouse, Rat and Human Pancreas
Prof Ken Walder
Xenome Grant - Research
- 2010: $6,500
- 2009: $6,500
Effects of novel insulin formulations on glucose homeostasis in streptozotocin-treated diabetic rats
Prof Ken Walder
VHS Grant - Research - VITAL HEALTH SCIENCES PTY LTD
- 2010: $72,500
Effects of amylin and leptin in sand rats
Prof Ken Walder
Amylin Pharmaceuticals
- 2010: $36,132
Effects of novel insulin formulations on body weight and glucose homeostasis in Psammomy obesus
Prof Ken Walder
VHS Grant - Research - VITAL HEALTH SCIENCES PTY LTD
- 2010: $17,000
New studies to investigate efficacy and safety of VVP808 (Part A)
Prof Ken Walder, Dr Nicky Konstantopoulos, Mr Scott Lee
Verva Pharmaceuticals Ltd
- 2011: $90,000
Investigate and characterise VVP808 interacting proteins (Part B)
Prof Ken Walder
Verva Pharmaceuticals Ltd
- 2013: $8,681
- 2012: $230,000
- 2011: $160,000
VVP100X - Research Program: Novel analogues for the treatment of type 2 diabetes
Prof Ken Walder
Verva Pharmaceuticals Ltd
- 2012: $280,000
- 2011: $70,000
The genetic basis of mercury sensitivity in pink disease survivors
Prof David Austin, Prof Ken Walder, Ms Shakuntla Gondalia, Kerrie Shandley, A/Prof Enzo Palombo, Dr Simon Knowles, Mr Matthew Garrecht
Coalition for SafeMinds - Research Grants
- 2014: $9,074
- 2013: $25,720
- 2012: $18,389
Effects of novel insulin formulations on glucose homeostasis in streptozotocin-treated diabetic rats
Prof Ken Walder
Jogra Nominees Pty Ltd - The Trustee for THE SM WEST FAMILY TRUST
- 2014: $6,727
- 2013: $6,727
Effects of encapsulation on bioavailability and distribution of orally administered milk lipid formulations
Prof Ken Walder
WRS Therapeutics, Jogra Nominees Pty Ltd - The Trustee for THE SM WEST FAMILY TRUST
- 2017: $15,000
- 2016: $82,899
- 2014: $12,633
Beak and Feather Disease Virus in wild avian populations in Australia
Prof Andy Bennett, Dr Mathew Berg, Prof Ken Walder, Ms Johanne (Hanne) Marie Martens
ESA - Holsworth Wildlife Research Endowment - 20 571 098 795
- 2019: $5,100
- 2017: $4,800
- 2016: $5,900
Beak and Feather Disease Virus in wild psittacine populations in Australia
Prof Andy Bennett, Dr Mathew Berg, Prof Ken Walder, Ms Johanne (Hanne) Marie Martens
Ecological Society Australia - Student Research Award
- 2017: $1,500
Repurposing drugs to treat bipolar depression using stem cell technology
Prof Ken Walder, Dr Chiara Bortolasci, Prof Michael Berk, Dr Amy Sinclair
Milken Institute and Baszucki Brain Research Fund - Bipoloar Disorder Grant
- 2022: $257,128
Can dietary supplementation with Krill-Oil improve ME/CFS symptoms?
Dr Lee Hamilton, Prof Ken Walder, Dr Giselle Allsopp, Dr Chris Shaw, Dr Greg Kowalski, Prof Clinton Bruce, Dr Craig Wright, Dr Rhiannon Snipe
Equity Trustees - The Mason Foundation National Medical Program
- 2023: $90,000
- 2022: $100,000
Biomarkers of negative symptoms, cognitive impairment and metabolic abnormalities in schizophrenia
Prof Alison Yung, Prof Sean Mcgee, Dr Luba Sominsky, Prof Ken Walder, Prof Julie Pasco, Prof Lana Williams, Dr Steve Moylan, Dr Mohammadreza Mohebbi, Dr Zoe Liu, Mr Marko Milicevic, Mr Wesley Plange
Royal Australian and New Zealand College of Psychiatrists Foundation Catalyst Grants
- 2022: $4,980
Other Funding Sources
Field-emission gun transmission electron microscope for the research in nanomaterials, metal alloys and biological sciences
Prof Ying (Ian) Chen, Prof Matthew Barnett, Prof Peter Hodgson, Prof Xungai Wang, Dr Takuya Tsuzuki, Dr Cui'E Wen, Dr Alexey Glushenkov, Prof Lingxue Kong, Prof Charles Sorrell, Dr Yuebin Zhang, Prof Vicki Chen, Dr Dominic Phelan, Prof Ken Walder, Dr Germanas Peleckis, A/Prof Simon Moulton, Prof John Beynon, Dr Xiaolin Wang, Prof David Cahill, Dr Pavel Cizek, Prof Neil Barnett, A/Prof Nicole Stanford, Prof Qipeng Guo
ARC LIEF - Linkage Infrastructure Equipment & Facilities Program
- 2011: $230,000
NHMRC Equipment Grant 2017 - RTCA iCELLigence instrument
Prof Ken Walder
NHMRC - Equipment Grant - Not R&D income countable (2017-current)
- 2018: $29,584
Neon Open System Electroporator
Prof Ken Walder, Prof Michael Berk
NHMRC - Equipment Grant - Not R&D income countable (2017-current)
- 2019: $11,347
NHMRC Equipment Grant 2019 - IMPACT
Prof Ken Walder
NHMRC - Equipment Grant - Not R&D income countable (2017-current)
- 2020: $20,304
EVOS M7000 image system - Thermo Fisher Scientific
Prof Ken Walder
NHMRC - Equipment Grant - Not R&D income countable (2017-current)
- 2022: $46,957
Supervisions
Srisaiyini Kidnapillai
Thesis entitled: Molecular Mechanisms of Action of Drugs Used to Treat Bipolar Disorder
Doctor of Philosophy (Medicine), School of Medicine
Christopher Kintakas
Thesis entitled: ADAMTS5 expression and function in myoblast fusion and muscle regeneration
Doctor of Philosophy (Medicine), School of Medicine
Sugeetha Ramakrishnan
Thesis entitled: The relationship between milk, mammary adipocytes and ECM in regulating murine mammary gland involution
Doctor of Philosophy (Medicine), School of Medicine
Vengama Naidu Modepalli
Thesis entitled: The Marsupial: A unique model for understanding the regulation of lung development
Doctor of Philosophy (Medicine), School of Medicine
Ashalyn Watt
Thesis entitled: Innate immunity in the breast and the role of the milk peptidome
Doctor of Philosophy (Medicine), School of Medicine
Bradley Hayward
Thesis entitled: A Global Approach to Dissecting Lipid-induced Impairment of Liver Gluconeogenesis
Doctor of Philosophy (Medicine), School of Medicine
Richard Bayles
Thesis entitled: A Genetic and Epigenetic Analysis of the Noradrenaline Transporter
Doctor of Philosophy (Medicine), School of Medicine
Lyndal Jane Bayles
Thesis entitled: Mitochondrial Target Discovery in Diabetic Skeletal Muscle
Doctor of Philosophy (Medicine), School of Medicine
Matthew Prior
Thesis entitled: AHI-I and NDRG2 Function in Skeletal Muscle and the Development of Type 2 Diabetes
Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences
Kiymet Bozaoglu
Thesis entitled: Metabolically Important Secreted Proteins in Psammomys obesus
Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences
Fiona Collier
Thesis entitled: Rhotekin 2, a Novel GTPase Effector Involved in Resistance to Apoptosis
Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences
Kristy Ann Bolton
Thesis entitled: Novel Secreted Proteins Involved in Obesity and Type 2 Diabetes
Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences
Subhadhcha Poonsatha
Thesis entitled: Identification and Characterisation of Novel Compound(s) for the Treatment of Type 2 Diabetes
Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences
Helena Stokes
Thesis entitled: Chlamydial Infection in Wild and Domesticated Avian Hosts
Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences
Johanne Marie Martens
Thesis entitled: Ecology of Beak and Feather Disease Virus in wild psittacines
Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences
Shauna Seneviratne
Thesis entitled: The effects of Ficolin and the Fibrinogen-like domain on ex vivo hematopoietic stem cell expansion.
Doctor of Philosophy (Biol & Chem), Institute for Frontier Materials
Smithamol Sithara
Thesis entitled: A beta-cell specific global approach for drug identification in Type 2 Diabetes
Doctor of Philosophy (Medicine), School of Medicine
Juliane Czeczor
Thesis entitled: Functional Role of Amyloid b42 in Systemic Glucose Metabolism
Doctor of Philosophy (Medicine), School of Medicine
Kirstie Anne De Jong
Thesis entitled: Characterisation of the Obese and T2D Heart - Protein Kinase D, a Possible Therapeutic Target
Doctor of Philosophy (Medicine), School of Medicine
Kyoko Hasebe
Thesis entitled: Investigating Neurobiological Mechanisms Linking Depression and Inflammation
Doctor of Philosophy (Medicine), School of Medicine
Parminder Kaur Ajji
Thesis entitled: Functional characterization of a novel ribosome inactivating protein from Momordica balsamina
Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences
Rajas Kale
Thesis entitled: Developing Neurostimulation Techniques to Investigate Antidepressant and Mood Modulating Behaviors
Doctor of Philosophy (Engineering), School of Engineering
Aung Kyaw Soe
Thesis entitled: A Modular Design Framework for Lab-On-a-Chips
Doctor of Philosophy (Information Technology), Institute for Intelligent Systems Research and Innovation
Simon Bond
Thesis entitled: The Role of Glyceraldehyde-3-Phosphate Dehydrogenase Acetylation in Liver Metabolism
Doctor of Philosophy (Medicine), School of Medicine
Daniel Fraher
Thesis entitled: Chemical Modulators of Lipid Abundance and Bone Development
Doctor of Philosophy (Medicine), School of Medicine
Anand Khedkar
Thesis entitled: Development and Evaluation of a Novel Insulin Analogue
Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences
Rajneesh Chaudhary
Thesis entitled: Zinc doped ferrite magnetic resonance imaging contrast agent for atherosclerosis
Doctor of Philosophy (Medicine), School of Medicine
Justin Eastwood
Thesis entitled: The Ecology and Evolution of Beak and Feather Disease Virus in Platycercus elegans
Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences
Vidhi Gaur
Thesis entitled: HDAC inhibition as a therapeutic potential to treat metabolic diseases
Doctor of Philosophy (Medicine), School of Medicine
Bingshan Li
Thesis entitled: Production and Characterisation of Powdered Fibrous Materials
Doctor of Philosophy (Engineering), Institute for Frontier Materials
James Trevaskis
Thesis entitled: Novel Hypothalamic Genes Involved in Body Weight Regulation in Psammomys obesus
Doctor of Philosophy, School of Exercise and Nutrition Sciences
Adam Southon
Thesis entitled: Novel Genes in the Liver of Diabetic Psammomys obesus
Master of Science, School of Health Sciences
Anthony Civitarese
Thesis entitled: Novel Genes in the Muscle of Obese-Diabetic Psammomys obesus
Doctor of Philosophy (Nutrition & Exercise) (Low Cost), School of Health Sciences