Prof Ken Walder

STAFF PROFILE

Position

Chair In Metabolic Diseases

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Qualifications

Doctor of Philosophy, Deakin University, 1998

Contact

ken.walder@deakin.edu.au
+61 3 522 72883

Biography

Professor Walder is the Chair of Metabolic Diseases in the School of Medicine and the Molecular and Medical Research SRC. His research focuses on obesity and type 2 diabetes, and mental health disorders, and in particular the discovery of novel treatments for these diseases. After spending 2 years at the National Institutes of Health in Phoenix, Arizona, Professor Walder returned to Deakin University where he has played a key role in the evolution of the Metabolic Research Unit. He has authored more than 75 academic publications and is named as an inventor on more than 40 patent applications. Professor Walder has worked closely with a number of industry partners, and is focused on conducting applied research with tangible outcomes that benefit Australia. In 2014, a compound discovered in Professor Walder’s laboratory successfully completed a Phase 2 clinical trial for the treatment of type 2 diabetes.

Read more on Ken's profile

Career highlights

A new drug for diabetes discovered in Prof Walder's laboratory successfully completed a phase 2 clinical trial, where it caused a significant reduction in plasma HbA1c levels (Simpson et al. Diabetes Care, 2014).

Research interests

Professor Walders research is primarily focused on the discovery and validation of novel drug treatments for complex diseases. This research utilises state of the art equipment and technologies, in combination with unique model systems and sample collections, to screen for small molecules that can be used to treat complex diseases. The novel drug candidates are tested in in vitro and in vivo model systems to establish their potential for development as therapeutics.

Affiliations

European Association for the Study of Diabetes

American Diabetes Association

Australian Diabetes Society

International Association for the Study of Obesity

North American Association for the Study of Obesity

Australian Society for the Study of Obesity

Teaching interests

5 PhD students

Medical Innovations component of HBS400 (Honours)

Units taught

HBS400 (Medical Innovations)

Knowledge areas

Metabolic diseases (obesity, type 2 diabetes, non-alcoholic fatty liver disease).

Mental health (depression, bipolar disorder, schizophrenia).

Genetics.

Drug discovery.

Conferences

Invited presentations at national and international conferences including:

Australian Diabetes Society Annual Scientific Meeting, Sydney, August 2013. Invited seminar presentation: “VVP808 and fatty liver disease”.


Baker-IDI Research Institute Seminar Series, Melbourne, October 2011. Invited seminar presentation: “Use of GES technology to discover a new insulin sensitising agent”.


Frontiers in Obesity Research, Melbourne, September 2011. Invited seminar presentation: “VVP808: A novel insulin sensitising agent”.


University of Melbourne Department of Medicine Seminar Series, Melbourne, May 2010. Invited seminar presentation: “VVP808: A novel insulin sensitising agent”.


Monash University Obesity Diabetes Institute, Melbourne, June 2010. Invited seminar presentation: “Mechanism of action of VVP808”.


MSD Diabetes Meeting, Sydney, October 11-12, 2008. Symposium presentation: “Overview of mitochondrial dysfunction in diabetes”.


GTCbio 3rd Metabolic Diseases World Summit, San Diego, USA, November 1-2, 2007. Symposium presentation: “Use of gene expression signatures to discover novel diabetes therapeutics”.


ASSO 15th Annual Scientific Meeting, Canberra, Australia, August 31-September 2, 2007. Symposium presentation: “The adipocyte as an endocrine organ”.


2nd International Congress on Prediabetes and the Metabolic Syndrome, Barcelona, Spain, April 25-28, 2007. Symposium presentation: “The mitochondrial protease PARL and type 2 diabetes”.


2nd Scientific Meeting of the Asia-Pacific Diabetes and Obesity Study Group, Kyoto, Japan, August 26-7, 2006. Symposium presentation: “CXS741, A Novel Secreted Protein Involved in the Pathogenesis of Obesity and Type 2 Diabetes”.


1st Scientific Meeting of the Asia-Pacific Diabetes and Obesity Study Group, Kobe, Japan, August 20-1, 2005. Symposium presentation: “Genetic variation in PSARL is associated with plasma insulin concentration”.

Awards

1998 Fogarty Fellowship (NIH)

2006 Smart Geelong Network Biotechnology Researcher of the Year

Projects

Professor Walder serves as a reviewer for the following journals:

Diabetes

Diabetologia

International Journal of Obesity

Molecular and General Genetics

Kidney International

Pancreas



Professor Walder regularly reviews research applications for national and international funding bodies, including NHMRC and ARC.

Publications

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2019

Prevalence of BFDV in wild breeding Platycercus elegans

J Eastwood, M Berg, R Ribot, K Buchanan, K Walder, A Bennett

(2019), Vol. 160, pp. 557-565, Journal of ornithology, Berlin, Germany, C1

journal

The therapeutic potential of mangosteen pericarp as an adjunctive therapy for bipolar disorder and schizophrenia

Melanie Ashton, Olivia Dean, Adam Walker, Chiara Bortolasci, Chee Ng, Malcolm Hopwood, Brian Harvey, Marisa Mller, John McGrath, Wolfgang Marx, Alyna Turner, Seetal Dodd, James Scott, Jon-Paul Khoo, Ken Walder, Jerome Sarris, Michael Berk

(2019), Vol. 10, pp. 1-17, Frontiers in psychiatry, Lausanne, Switzerland, C1

journal

Identification of Chlamydia gallinacea in a parrot and in free-range chickens in Australia

H Stokes, J Martens, A Chamings, K Walder, M Berg, Y Segal, A Bennett

(2019), pp. 1-3, Australian veterinary journal, Chichester, Eng., C1

journal

The compensatory antioxidant response system with a focus on neuroprogressive disorders

G Morris, B Puri, A Walker, M Berk, K Walder, C Bortolasci, W Marx, A Carvalho, M Maes

(2019), Vol. 95, Progress in neuro-psychopharmacology and biological psychiatry, Amsterdam, The Netherlands, C1

journal

Persistence of beak and feather disease virus (BFDV) infection in wild Crimson Rosellas (Platycercus elegans)

Johanne Martens, Helena Stokes, Justin Eastwood, Shane Raidal, Andrew Peters, Mathew Berg, Ken Walder, Michael Magrath, Andrew Bennett

(2019), pp. 1-5, Emu - Austral ornithology, Abingdon, Eng., C1

journal

Modulation of high fat diet-induced microbiome changes, but not behaviour, by minocycline

K Hasebe, L Rivera, C Smith, T Allnutt, T Crowley, T Nelson, O Dean, S McGee, K Walder, L Gray

(2019), Vol. 82, pp. 309-318, Brain, behavior, and immunity, Amsterdam, The Netherlands, C1

journal

Myalgic encephalomyelitis/chronic fatigue syndrome: from pathophysiological insights to novel therapeutic opportunities

G Morris, B Puri, A Walker, M Maes, A Carvalho, K Walder, C Mazza, M Berk

(2019), Vol. 148, pp. 1-20, Pharmacological research, Amsterdam, The Netherlands, C1

journal
2018

The role of hypernitrosylation in the pathogenesis and pathophysiology of neuroprogressive diseases

G Morris, K Walder, A Carvalho, S Tye, K Lucas, M Berk, M Maes

(2018), Vol. 84, pp. 453-469, Neuroscience and biobehavioral reviews, Amsterdam, The Netherlands, C1

journal

Mechanisms underpinning the polypharmacy effects of medications in psychiatry

Chiara Bortolasci, Briana Spolding, Edward Callaly, Sheree Martin, Bruna Panizzutti, Srisaiyini Kidnapillai, Timothy Connor, Kyoko Hasebe, Mohammadreza Mohebbi, Olivia Dean, Sean McGee, Seetal Dodd, Laura Gray, Michael Berk, Ken Walder

(2018), Vol. 21, pp. 582-591, The international journal of neuropsychopharmacology, Oxford, Eng., C1

journal

Purification and functional characterization of recombinant balsamin, a ribosome-inactivating protein from Momordica balsamina

Parminder Ajji, Shailendra Sonkar, Ken Walder, Munish Puri

(2018), Vol. 114, pp. 226-234, International journal of biological macromolecules, Amsterdam, The Netherlands, C1

journal

The endoplasmic reticulum stress response in neuroprogressive diseases: emerging pathophysiological role and translational implications

Gerwyn Morris, Basant Puri, Ken Walder, Michael Berk, Brendon Stubbs, Michael Maes, Andr Carvalho

(2018), Vol. 55, pp. 8765-8787, Molecular neurobiology, New York, N.Y., C1

journal

Bioenergetics and synaptic plasticity as potential targets for individualizing treatment for depression

J Price, Carrie Bronars, Sophie Erhardt, Kathyrn Cullen, Lilly Schwieler, Michael Berk, Ken Walder, Sean McGee, Mark Frye, Susannah Tye

(2018), Vol. 90, pp. 212-220, Neuroscience and biobehavioral reviews, Amsterdam, The Netherlands, C1

journal

APP deficiency results in resistance to obesity but impairs glucose tolerance upon high fat feeding

J Czeczor, A Genders, K Aston-Mourney, T Connor, L Hall, K Hasebe, M Ellis, K De Jong, D Henstridge, P Meikle, M Febbraio, K Walder, S McGee

(2018), Vol. 237, pp. 311-322, Journal of endocrinology, Bradley Stok, Eng., C1

journal

The putative role of oxidative stress and inflammation in the pathophysiology of sleep dysfunction across neuropsychiatric disorders: Focus on chronic fatigue syndrome, bipolar disorder and multiple sclerosis

Gerwyn Morris, Brendon Stubbs, Cristiano Khler, Ken Walder, Anastasiya Slyepchenko, Michael Berk, Andr Carvalho

(2018), Vol. 41, pp. 255-265, Sleep medicine reviews, Amsterdam, The Netherlands, C1

journal

Diet during pregnancy is implicated in the regulation of hypothalamic RNA methylation and risk of obesity in offspring

Antony Kaspi, Ishant Khurana, Mark Ziemann, Timothy Connor, Briana Spolding, Paul Zimmet, Ken Walder, Assam El-Osta

(2018), Vol. 62, pp. 1-10, Molecular nutrition and food research, Weinheim, Germany, C1

journal

Pair fidelity in long-lived parrots: genetic and behavioural evidence from the Crimson Rosella ( Platycercus elegans )

Justin Eastwood, Mathew Berg, Raoul Ribot, Helena Stokes, Johanne Martens, Katherine Buchanan, Ken Walder, Andrew Bennett

(2018), Vol. 118, pp. 369-374, Emu: Austral ornithology, Abingdon, Eng., C1

journal

The use of a gene expression signature and connectivity map to repurpose drugs for bipolar disorder

Srisaiyini Kidnapillai, Chiara Bortolasci, Madhara Udawela, Bruna Panizzutti, Briana Spolding, Timothy Connor, Andrew Sanigorski, Olivia Dean, Tamsyn Crowley, Stphane Jamain, Laura Gray, Elizabeth Scarr, Marion Leboyer, Brian Dean, Michael Berk, Ken Walder

(2018), pp. 1-9, World journal of biological psychiatry, London, Eng., C1

journal

Mediator effects of parameters of inflammation and neurogenesis from a N-acetyl cysteine clinical-trial for bipolar depression

Bruna Panizzutti, Chiara Bortolasci, Kyoko Hasebe, Srisaiyini Kidnapillai, Laura Gray, Ken Walder, Michael Berk, Mohammadreza Mohebbi, Seetal Dodd, Clarissa Gama, Pedro Magalhes, Susan Cotton, Flvio Kapczinski, Ashley Bush, Gin Malhi, Olivia Dean

(2018), Vol. 30, pp. 334-341, Acta neuropsychiatrica, Cambridge, Eng., C1

journal

Psammomys obesus: a natural diet-controlled model for diabetes and cardiovascular diseases

Rajneesh Chaudhary, Ken Walder, Christoph Hagemeyer, Jagat Kanwar

(2018), Vol. 20, pp. 1-10, Current atherosclerosis reports, New York, N.Y., C1

journal

Association between childhood trauma exposure and pro-inflammatory cytokines in schizophrenia and bipolar-I disorder

Yann Quid, Chiara Bortolasci, Briana Spolding, Srisaiyini Kidnapillai, Oliver Watkeys, Sarah Cohen-Woods, Michael Berk, Vaughan Carr, Ken Walder, Melissa Green

(2018), pp. 1-9, Psychological medicine, Cambridge, Eng., C1

journal
2017

Nitrosative stress, hypernitrosylation, and autoimmune responses to nitrosylated proteins: new pathways in neuroprogressive disorders Including depression and chronic fatigue syndrome.

G Morris, M Berk, H Klein, K Walder, P Galecki, M Maes

(2017), Vol. 54, pp. 4271-4291, Molecular neurobiology, Berlin, Germany, C1

journal

Gene expression signature: a powerful approach for drug discovery in diabetes

S Sithara, T Crowley, K Walder, K Aston-Mourney

(2017), Vol. 232, pp. R131-R139, Journal of endocrinology, Bristol, Eng., C1

journal

A model of the mitochondrial basis of bipolar disorder

G Morris, K Walder, S McGee, O Dean, S Tye, M Maes, M Berk

(2017), Vol. 74, pp. 1-20, Neuroscience and biobehavioral reviews, Amsterdam, The Netherlands, C1

journal

Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice

V Gaur, T Connor, K Venardos, D Henstridge, S Martin, C Swinton, S Morrison, K Aston-Mourney, S Gehrig, R van Ewijk, G Lynch, M Febbraio, G Steinberg, M Hargreaves, K Walder, S McGee

(2017), Vol. 19, pp. 936-943, Diabetes, obesity and metabolism, Chichester, Eng., C1

journal

Lysine post-translational modification of glyceraldehyde-3-phosphate dehydrogenase regulates hepatic and systemic metabolism

S Bond, K Howlett, G Kowalski, S Mason, T Connor, A Cooper, V Streltsov, C Bruce, K Walder, S McGee

(2017), Vol. 31, pp. 2592-2602, FASEB journal, Bethesda, Md., C1

journal

Adjunctive N-acetylcysteine in depression: exploration of interleukin-6, C-reactive protein and brain-derived neurotrophic factor

K Hasebe, L Gray, C Bortolasci, B Panizzutti, M Mohebbi, S Kidnapillai, B Spolding, K Walder, M Berk, G Malhi, S Dodd, O Dean

(2017), Vol. 29, pp. 337-346, Acta neuropsychiatrica, Cambridge, Eng., C1

journal

Exercise and the skeletal muscle epigenome

S McGee, K Walder

(2017), Vol. 7, Cold Spring Harbor Perspectives in Medicine, Cold Spring Harbor, N.Y., C1

journal

Balsamin induces apoptosis in breast cancer cells via DNA fragmentation and cell cycle arrest

P Ajji, M Binder, K Walder, M Puri

(2017), Vol. 432, pp. 189-198, Molecular and cellular biochemistry, New York, N.Y., C1

journal

Validation of a portable low-power deep brain stimulation device through anxiolytic effects in a laboratory rat model

A Kouzani, R Kale, P Zarate-Garza, M Berk, K Walder, S Tye

(2017), Vol. 25, pp. 1365-1374, IEEE transactions on neural systems and rehabilitation engineering, Piscataway, N.J., C1

journal
2016

The neuro-immune pathophysiology of central and peripheral fatigue in systemic immune-inflammatory and neuro-immune diseases

G Morris, M Berk, P Galecki, K Walder, M Maes

(2016), Vol. 53, pp. 1195-1219, Molecular neurobiology, Berlin, Germany, C1

journal

The deleterious effects of oxidative and nitrosative stress on palmitoylation, membrane lipid rafts and lipid-based cellular signalling : new drug targets in neuroimmune disorders

G Morris, K Walder, B Puri, M Berk, M Maes

(2016), Vol. 53, pp. 4638-4658, Molecular neurobiology, New York, N.Y., C1

journal

Engineered atherosclerosis-specific zinc ferrite nanocomplex-based MRI contrast agents

R Chaudhary, K Roy, R Kanwar, K Walder, J Kanwar

(2016), Vol. 14, pp. 1-17, Journal of nanobiotechnology, London, Eng., C1

journal

Deficiency in apoptosis-inducing factor recapitulates chronic kidney disease via aberrant mitochondrial homeostasis

M Coughlan, G Higgins, T-V Nguyen, S Penfold, V Thallas-Bonke, S Tan, G Ramm, N Van Bergen, D Henstridge, K Sourris, B Harcourt, I Trounce, P Robb, A Laskowski, S McGee, A Genders, K Walder, B Drew, P Gregorevic, H Qian, M Thomas, G Jerums, R Macisaac, A Skene, D Power, E Ekinci, X Wijeyeratne, L Gallo, M Herman-Edelstein, M Ryan, M Cooper, D Thorburn, J Forbes

(2016), Vol. 65, pp. 1085-1098, Diabetes, Alexandria, Va., C1

journal

DNA methylation regulates hypothalamic gene expression linking parental diet during pregnancy to the offspring's risk of obesity in Psammomys obesus

I Khurana, A Kaspi, M Ziemann, T Block, T Connor, B Spolding, A Cooper, P Zimmet, A El-Osta, K Walder

(2016), Vol. 40, pp. 1079-1088, International journal of obesity, London, Eng., C1

journal

Functional analysis of a Type-I ribosome inactivating protein balsamin from Momordica balsamina with anti-microbial and DNase activity

P Ajji, K Walder, M Puri

(2016), Vol. 71, pp. 265-271, Plant foods for human nutrition, New York, N.Y., C1

journal

Nucleus accumbens deep-brain stimulation efficacy in ACTH-pretreated rats: alterations in mitochondrial function relate to antidepressant-like effects

Y Kim, S McGee, J Czeczor, A Walker, R Kale, A Kouzani, K Walder, M Berk, S Tye

(2016), Vol. 6, pp. 1-7, Translational psychiatry, London, Eng., C1

journal

The role of the microbial metabolites including tryptophan catabolites and short chain fatty acids in the pathophysiology of immune-inflammatory and neuroimmunue disease.

G Morris, M Berk, A Carvalho, J Caso, Y Sanz, K Walder, M Maes

(2016), pp. 1-20, Molecular neurobiology, Berlin, Germany, C1

journal

Disruption of the class IIa HDAC corepressor complex increases energy expenditure and lipid oxidation

V Gaur, T Connor, A Sanigorski, S Martin, C Bruce, D Henstridge, S Bond, K McEwen, L Kerr-Bayles, T Ashton, C Fleming, M Wu, L Pike Winer, D Chen, G Hudson, J Schwabe, K Baar, M Febbraio, P Gregorevic, F Pfeffer, K Walder, M Hargreaves, S McGee

(2016), Vol. 16, pp. 2802-2810, Cell reports, New York, N.Y., C1

journal

Pathways of acetyl-CoA metabolism involved in the reversal of palmitate-induced glucose production by metformin and salicylate

B Hayward, J Molero, K Windmill, A Sanigorski, J Weir, N McRae, K Aston-Mourney, B Osborne, B Liao, K Walder, P Meikle, N Konstantopoulos, C Schmitz-Peiffer

(2016), Vol. 124, pp. 602-612, Experimental and clinical endocrinology and diabetes, Munich, Germany, C1

journal
2015

Leptin's metabolic and immune functions can be uncoupled at the ligand/receptor interaction level.

L Zabeau, C Jensen, S Seeuws, K Venken, A Verhee, D Catteeuw, G van Loo, H Chen, K Walder, J Hollis, S Foote, M Morris, J Van der Heyden, F Peelman, B Oldfield, J Rubio, D Elewaut, J Tavernier

(2015), Vol. 72, pp. 629-644, Cellular and Molecular Life Sciences, Switzerland, C1

journal

Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses

G Morris, M Berk, K Walder, M Maes

(2015), Vol. 13, pp. 1-23, BMC Medicine, London, Eng., C1

journal

Mitochondrial dysfunction in the pathophysiology of bipolar disorder: effects of pharmacotherapy

E Callaly, K Walder, G Morris, M Maes, M Debnath, M Berk

(2015), Vol. 15, pp. 355-365, Mini-reviews in medicinal chemistry, Amsterdam, The Netherlands, C1

journal

Prevalence of beak and feather disease virus in wild Platycercus elegans: comparison of three tissue types using a probe-based real-time qPCR test

J Eastwood, M Berg, B Spolding, K Buchanan, A Bennett, K Walder

(2015), Vol. 63, pp. 1-8, Australian journal of zoology, Clayton, Vic., C1

journal

The putative role of viruses, bacteria, and chronic fungal biotoxin exposure in the genesis of intractable fatigue accompanied by cognitive and physical disability

G Morris, M Berk, K Walder, M Maes

(2015), Vol. In press, pp. 1-22, Molecular neurobiology, Clifton, N.J., C1

journal

Evolution of optogenetic microdevices

R Kale, A Kouzani, K Walder, M Berk, S Tye

(2015), Vol. 2, pp. 1-11, Neurophotonics, Bellingham, W.A., C1

journal

Lipid abundance in zebrafish embryos is regulated by complementary actions of the endocannabinoid system and retinoic acid pathway

D Fraher, M Ellis, S Morrison, S McGee, A Ward, K Walder, Y Gibert

(2015), Vol. 156, pp. 3596-3609, Endocrinology, Bethesda, Md., C1

journal

CXCR4 Antagonism attenuates the development of diabetic cardiac fibrosis

P Chu, K Walder, D Horlock, D Williams, E Nelson, M Byrne, K Jandeleit-Dahm, P Zimmet, D Kaye

(2015), Vol. 10, pp. 1-13, PLoS One, San Francisco, CA, C1

journal

Citalopram and sertraline exposure compromises embryonic bone development

D Fraher, J Hodge, F Collier, J McMillan, R Kennedy, M Ellis, G Nicholson, K Walder, S Dodd, M Berk, J Pasco, L Williams, Y Gibert

(2015), Vol. In press, pp. 1-9, Molecular psychiatry, Hampshire, Eng., C1

journal

Wireless optogenetics: an exploration of portable microdevices for small animal photostimulation

R Kale, A Kouzani, M Berk, K Walder, J Berk, S Tye

(2015), Vol. 20, pp. 225-230, Procedia technology, Amsterdam, The Netherlands, C1

journal
2014

Rapid development of non-alcoholic steatohepatitis in Psammomys obesus (Israeli Sand Rat)

B Spolding, T Connor, C Wittmer, L Abreu, A Kaspi, M Ziemann, G Kaur, A Cooper, S Morrison, S Lee, A Sinclair, Y Gibert, J Trevaskis, J Roth, A El-Osta, R Standish, K Walder

(2014), Vol. 9, pp. 1-7, PLoS one, San Francisco, Calif., C1

journal

Phylogenetic analysis of beak and feather disease virus across a host ring-species complex

J Eastwood, M Berg, R Ribot, S Raidal, K Buchanan, K Walder, A Bennett

(2014), Vol. 111, pp. 14153-14158, Proceedings of the national scademy of sciences of the USA, Washington, DC, C1

journal

Efficacy and safety of oral methazolamide in patients with type 2 diabetes : a 24-week, placebo-controlled, double-blind study

R Simpson, G Nicholson, J Proietto, A Sarah, K Sanders, G Phillips, J Chambers, R MacGinley, N Orford, K Walder, G Krippner, K Skoff, V Wacher

(2014), Vol. 37, pp. 3121-3123, Diabetes Care, Alexandria VA., C1

journal

Non-referenced genome assembly from epigenomic short-read data

A Kaspi, M Ziemann, S Keating, I Khurana, T Connor, B Spolding, A Cooper, R Lazarus, K Walder, P Zimmet, A El-Osta

(2014), Vol. 9, pp. 1329-1338, Epigenetics, C1

journal

Genetic variation associated with hypersensitivity to mercury.

D Austin, B Spolding, S Gondalia, K Shandley, E Palombo, S Knowles, K Walder

(2014), Vol. 21, pp. 236-241, Toxicology International, India, C1-1

journal
2013

Genetic basis for the increased expression of vacuolar H+ translocating ATPase genes upon imatinib treatment in human lymphoblastoid cells

H Kulkarni, H Gring, J Curran, V Diego, T Dyer, S Cole, K Walder, G Collier, J Blangero, M Carless

(2013), Vol. 71, pp. 1095-1100, Cancer Chemotherapy and Pharmacology, C1

journal

Chronic adrenocorticotrophic hormone treatment alters tricyclic antidepressant efficacy and prefrontal monoamine tissue levels

A Walker, S Burnett, K Hasebe, J McGillivray, L Gray, S McGee, K Walder, M Berk, S Tye

(2013), Vol. 242, pp. 76-83, Behavioural Brain Research, C1

journal

Targeted multimodal liposomes for nano-delivery and imaging: an avenger for drug resistance and cancer.

S Gurudevan, R Kanwar, R Veedu, S Sasidharan, R Kennedy, K Walder, N Prasad, J Kanwar

(2013), Vol. 13, pp. 322-334, Current gene therapy, Bussum, The Netherlands, C1

journal
2012

The small leucine-rich proteoglycan, biglycan, is highly expressed in adipose tissue of Psammomys obesus and is associated with obesity and type 2 diabetes

K Bolton, D Segal, K Walder

(2012), Vol. 6, pp. 67-72, Biologics: Targets and Therapy, C1

journal

Methazolamide is a new hepatic insulin sensitizer that lowers blood glucose in vivo

N Konstantopoulos, J Molero, S McGee, B Spolding, T Connor, M De Vries, S Wanyonyi, R Fahey, S Morrison, C Swinton, S Jones, A Cooper, L Garcia-Guerra, V Foletta, G Krippner, S Andrikopoulos, K Walder

(2012), Vol. 61, pp. 2146-2154, Diabetes, C1

journal

Design of a miniature UHF PIFA for DBS implants

M Hosain, A Kouzani, S Tye, K Walder, L Kong

(2012), pp. 485-489, CME 2012 : Proceedings of the 2012 IEEE/ICME International Conference on Complex Medical Engineering, Kobe, Japan, E1

conference

Association of differential gene expression with imatinib mesylate and omacetaxine mepesuccinate toxicity in lymphoblastoid cell lines

H Kulkarni, H Gring, V Diego, S Cole, K Walder, G Collier, J Blangero, M Carless

(2012), Vol. 5, BMC Medical Genomics, C1

journal

Genetic variation in SH3-domain GRB2-like (endophilin)-interacting protein 1 has a major impact on fat mass

N Cummings, K Shields, J Curran, K Bozaoglu, J Trevaskis, K Gluschenko, G Cai, A Comuzzie, T Dyer, K Walder, P Zimmet, G Collier, J Blangero, J Jowett

(2012), Vol. 36, pp. 201-206, International Journal of Obesity, C1

journal
2011

A gene expression signature for insulin resistance

N Konstantopoulos, V Foletta, D Segal, K Shields, A Sanigorski, K Windmill, C Swinton, T Connor, S Wanyonyi, T Dyer, R Fahey, R Watt, J Curran, J Molero, G Krippner, G Collier, D James, J Blangero, J Jowett, K Walder

(2011), Vol. 43, pp. 110-120, Physiological Genomics, C1

journal

A head mountable deep brain stimulation device for laboratory animals

A Kouzani, S Tye, K Walder, L Kong

(2011), Vol. 121 LNEE, pp. 275-280, Lecture Notes in Electrical Engineering, B1

chapter

Deficiency in interferon-? results in reduced body weight and better glucose tolerance in mice

N Wong, B Fam, G Cempako, G Steinberg, K Walder, T Kay, J Proietto, S Andrikopoulos

(2011), Vol. 152, pp. 3690-3699, Endocrinology, C1

journal
2010

Effects of rosiglitazone on intramyocellular lipid accumulation in Psammomys obesus

J Molero, S Lee, I Leizerman, A Chajut, A Cooper, K Walder

(2010), Vol. 1802, pp. 235-239, B B A - Molecular Basis of Disease, Amsterdam, The Netherlands, C1

journal

Genetic variation in PARL influences mitochondrial content

J Curran, J Jowett, L Abraham, L Diepeveen, K Elliott, T Dyer, L Kerr-Bayles, M Johnson, A Comuzzie, E Moses, K Walder, G Collier, J Blangero, A Kissebah

(2010), Vol. 127, pp. 183-190, Human Genetics, C1

journal

The characterization of Abelson helper integration site-1 in skeletal muscle and its links to the metabolic syndrome

M Prior, V Foletta, J Jowett, D Segal, M Carless, J Curran, T Dyer, E Moses, A McAinch, N Konstantopoulos, K Bozaoglu, G Collier, D Cameron-Smith, J Blangero, K Walder

(2010), Vol. 59, pp. 1057-1064, Metabolism: Clinical and Experimental, C1

journal

Chemerin, a novel adipokine in the regulation of angiogenesis

K Bozaoglu, J Curran, C Stocker, M Zaibi, D Segal, N Konstantopoulos, S Morrison, M Carless, T Dyer, S Cole, H Goring, E Moses, K Walder, M Cawthorne, J Blangero, J Jowett

(2010), Vol. 95, pp. 2476-2485, Journal of Clinical Endocrinology and Metabolism, C1

journal

Regulation of skeletal muscle oxidative capacity and insulin signaling by the Mitochondrial Rhomboid Protease PARL

A Civitarese, P MacLean, S Carling, L Kerr-Bayles, R McMillan, A Pierce, T Becker, C Moro, J Finlayson, N Lefort, C Newgard, L Mandarino, W Cefalu, K Walder, G Collier, M Hulver, S Smith, E Ravussin

(2010), Vol. 11, pp. 412-426, Cell metabolism, Cambridge, Mass., C1

journal
2009

NDRG2, a novel regulator of myoblast proliferation, is regulated by anabolic and catabolic factors

V Foletta, M Prior, N Stupka, K Carey, D Segal, S Jones, C Swinton, S Martin, D Cameron-Smith, K Walder

(2009), Vol. 587, pp. 1619-1634, Journal of Physiology, C1

journal

RTKN2 induces NF-kappaB dependent resistance to intrinsic apoptosis in HEK cells and regulates BCL-2 genes in human CD4 + lymphocytes

F Collier, A Loving, A Baker, J Mcleod, K Walder, M Kirkland

(2009), Vol. 2009, pp. 9-23, Journal of Cell Death, C1

journal

Identification of secreted proteins associated with obesity and type 2 diabetes in Psammomys obesus

K Bolton, D Segal, J McMillan, A Sanigorski, G Collier, K Walder

(2009), Vol. 33, pp. 1153-1165, International Journal of Obesity, C1

journal

Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity

H Su, J Gunter, M de Vries, T Connor, S Wanyonyi, F Newell, D Segal, J Molero, O Reizes, J Prins, L Hutley, K Walder, J Whitehead

(2009), Vol. 386, pp. 351-355, Biochemical and Biophysical Research Communications, C1

journal

Chemerin is associated with metabolic syndrome phenotypes in a Mexican-American population

K Bozaoglu, D Segal, K Shields, N Cummings, J Curran, A Comuzzie, M Mahaney, D Rainwater, J Vandeberg, J MacCluer, G Collier, J Blangero, K Walder, J Jowett

(2009), Vol. 94, pp. 3085-3088, Journal of Clinical Endocrinology and Metabolism, C1

journal

Enhanced proliferation of human skeletal muscle precursor cells derived from elderly donors cultured in estimated physiological (5%) oxygen

S Martin, F Collier, M Kirkland, K Walder, N Stupka

(2009), Vol. 61, pp. 93-107, Cytotechnology, C1

journal
2008

Decorin is a secreted protein associated with obesity and type 2 diabetes

K Bolton, D Segal, J McMillan, J Jowett, L Heilbronn, K Abberton, P Zimmet, D Chisholm, G Collier, K Walder

(2008), Vol. 32, pp. 1113-1121, International Journal of Obesity, C1-1

journal
2007

Chemerin is a novel adipokine associated with obesity and metabolic syndrome

K Bozaoglu, K Bolton, J McMillan, P Zimmet, J Jowett, G Collier, K Walder, D Segal

(2007), Vol. 148, pp. 4687-4694, Endocrinology, C1

journal

Localization and expression of selenoprotein S in the testis of Psammomys obesus

K Windmill, J Tenne-Brown, R Bayles, J Trevaskis, Y Gao, K Walder

(2007), Vol. 38, pp. 97-101, Journal of molecular histology, Amsterdam, The Netherlands, C1

journal

SEPS1 protects RAW264.7 cells from pharmacological ER stress agent-induced apoptosis

K Kim, Y Gao, K Walder, G Collier, J Skelton, A Kissebah

(2007), Vol. 354, pp. 127-132, Biochemical and Biophysical Research Communications, C1

journal

Secretion of the glucose-regulated selenoprotein SEPS1 from hepatoma cells

Y Gao, J Pagnon, H Feng, N Konstantopolous, J Jowett, K Walder, G Collier

(2007), Vol. 356, pp. 636-641, Biochemical and Biophysical Research Communications, C1

journal
2006

Identification of novel genes expressed during rhabdomyosarcoma differentiation using cDNA microarrays

K Carey, D Segal, R Klein, A Sanigorski, K Walder, G Collier, D Cameron-Smith

(2006), Vol. 56, pp. 246-255, Pathology International, C1

journal

Activation of the selenoprotein SEPS1 gene expression by pro-inflammatory cytokines in HepG2 cells

Y Gao, N Hannan, S Wanyonyi, N Konstantopolous, J Pagnon, H Feng, J Jowett, K Kim, K Walder, G Collier

(2006), Vol. 33, pp. 246-251, Cytokine, C1

journal

Association of genetic variation within UBL5 with phenotypes of metabolic syndrome

K Bozaoglu, J Curran, K Elliott, K Walder, T Dyer, D Rainwater, J Vandeberg, A Comuzzie, G Collier, P Zimmet, J MacCluer, J Jowett, J Blangero

(2006), Vol. 78, pp. 147-159, Human Biology, C1

journal
2005

The mitochondrial rhomboid protease PSARL is a new candidate gene for type 2 diabetes

K Walder, L Kerr-Bayles, A Civitarese, J Jowett, J Curran, K Elliott, J Trevaskis, N Bishara, P Zimmet, L Mandarino, E Ravussin, J Blangero, A Kissebah, G Collier

(2005), Vol. 48, pp. 459-468, Diabetologia, C1

journal

Genetic variation in selenoprotein S influences inflammatory response

J Curran, J Jowett, K Elliott, Y Gao, K Gluschenko, J Wang, D Azim, G Cai, M Mahaney, A Comuzzie, T Dyer, K Walder, P Zimmet, J MacCluer, G Collier, A Kissebah, J Blangero

(2005), Vol. 37, pp. 1234-1241, Nature Genetics, C1-1

journal

SH3-domain GRB2-like (endophilin) interacting protein 1 (SGIP1), a novel neuronal protein that regulates energy balance

J Trevaskis, K Walder, V Foletta, L Kerr-Bayles, J McMillan, A Cooper, S Lee, K Bolton, M Prior, R Fahey, K Whitecross, G Morton, M Schwartz, G Collier

(2005), Vol. 146, pp. 3757-3764, Endocrinology, C1-1

journal

PGC-1? gene expression is down-regulated by Akt-mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle

R Southgate, C Bruce, A Carey, G Steinberg, K Walder, R Monks, M Watt, J Hawley, M Birnbaum, M Febbraio

(2005), Vol. 19, pp. 2072-2074, FASEB Journal, C1-1

journal
2004

Identification and characterization of a lymphocytic Rho-GTPase effector: Rhotekin-2

F Collier, C Gregorio-King, T Gough, C Talbot, K Walder, M Kirkland

(2004), Vol. 324, pp. 1360-1369, Biochemical and Biophysical Research Communications, C1

journal

Identification of hypothalamic genes implicated in the development of obesity in Psammomys obesus using differential display PCR

J Trevaskis, J McMillan, K Windmill, K Walder, G Collier

(2004), Vol. 137, pp. 65-73, Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, C1

journal

Regulation of the selenoprotein SelS by glucose deprivation and endoplasmic reticulum stress - SelS is a novel glucose-regulated protein

Y Gao, H Feng, K Walder, K Bolton, T Sunderland, N Bishara, M Quick, L Kantham, G Collier

(2004), Vol. 563, pp. 185-190, FEBS Letters, C1

journal

c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action

J Molero, T Jensen, P Withers, M Couzens, H Herzog, C Thien, W Langdon, K Walder, M Murphy, D Bowtell, D James, G Cooney

(2004), Vol. 114, pp. 1326-1333, Journal of Clinical Investigation, C1

journal

Genetic variation in BEACON influences quantitative variation in metabolic syndrome-related phenotypes

J Jowett, K Elliott, J Curran, N Hunt, K Walder, G Collier, P Zimmet, J Blangero

(2004), Vol. 53, pp. 2467-2472, Diabetes, C1

journal
2003

Obesity and diabetes gene discovery approaches

K Walder, D Segal, J Jowett, J Blangero, G Collier

(2003), Vol. 9, pp. 1357-1372, Current Pharmaceutical Design, C1

journal

Genetic studies in Psammomys obesus

K Walder, D Segal, J Jowett, J Blangero, P Zimmet, G Collier

(2003), Vol. 9, pp. 275-278, Progress in obesity research, Eastleigh, England, C1

journal

Transcriptional profiling and gene discovery

G Collier, A De Silva, J Tenne-Brown, A Sanigorski, D Segal, L Kantham, K Walder

(2003), Vol. 9, pp. 36-39, Progress in obesity research, London, England, C1

journal

Elevation in Tanis expression alters glucose metabolism and insulin sensitivity in H4IIE cells

Y Gao, K Walder, T Sunderland, L Kantham, H Feng, M Quick, N Bishara, A De Silva, G Augert, J Tenne-Brown, G Collier

(2003), Vol. 52, pp. 929-934, Diabetes, C1

journal

The taq IA and Ser311Cys polymorphisms in the dopamine D2 receptor gene and obesity

A Southon, K Walder, A Sanigorski, P Zimmet, G Nicholson, M Kotowicz, G Collier

(2003), Vol. 16, pp. 72-76, Diabetes, nutrition & metabolism, Milano, Italy, C1

journal

Beacon interacts with cdc2/cdc28-like kinases

L Kantham, L Kerr-Bayles, N Godde, M Quick, R Webb, T Sunderland, J Bond, K Walder, G Augert, G Collier

(2003), Vol. 304, pp. 125-129, Biochemical and biophysical research communications, New York, N.Y., C1

journal

ORP3 splice variants and their expression in human tissues and hematopoietic cells

F Collier, C Gregorio-King, J Apostolopoulos, K Walder, M Kirkland

(2003), Vol. 22, pp. 1-9, DNA and Cell Biology, C1-1

journal
2002

Which genes are important in the development of type 2 diabetes?

G Collier, K Walder, A De Silva, S Morgan, D Segal, L Kantham, G Augert

(2002), pp. 175-186, Insulin resistance and insulin resistance syndrome, London, England, B1

chapter

Tanis: A link between type 2 diabetes and inflammation?

K Walder, L Kantham, J McMillan, J Trevaskis, L Kerr, A De Silva, T Sunderland, N Godde, Y Gao, N Bishara, K Windmill, J Tenne-Brown, G Augert, P Zimmet, G Collier

(2002), Vol. 51, pp. 1859-1866, Diabetes, C1

journal

Elevated hypothalamic beacon gene expression in Psammomys obesus prone to develop obesity and type 2 diabetes

K Walder, E Ziv, R Kalman, K Whitecross, E Shafrir, P Zimmet, G Collier

(2002), Vol. 26, pp. 605-609, International Journal of Obesity, C1

journal

Calpain 3 gene expression in skeletal muscle is associated with body fat content and measures of insulin resistance

K Walder, J McMillan, N Lapsys, A Kriketos, J Trevaskis, A Civitarese, A Southon, P Zimmet, G Collier

(2002), Vol. 26, pp. 442-449, International Journal of Obesity, C1

journal

New approaches to gene discovery with animal models of obesity and diabetes

G Collier, K Walder, A De Silva, J Tenne-Brown, A Sanigorski, D Segal, L Kantham, G Augert

(2002), Vol. 967, pp. 403-413, Annals of the New York academy of science, New York, N.Y., C1

journal

A custom-built insulin resistance gene chip

K Walder, D Segal, S Chehab, G Augert, D Cameron-Smith, M Hargreaves, G Collier

(2002), Vol. 967, pp. 274-282, Annals of the New York Academy of Sciences, New York, N.Y., C1

journal
2001

Effects of beacon administration on energy expenditure and substrate utilisation in Psammomys obesus (Israeli sand rats)

K Walder, J McMillan, S Lee, A Civitarese, P Zimmet, G Collier

(2001), Vol. 25, pp. 1281-1285, International journal of obesity, London, England, C1

journal

Genetic variation and obesity in Australian women: A prospective study.

A De Silva, K Walder, E Boyko, K Whitecross, G Nicholson, M Kolowitz, J Pasco, G Collier

(2001), Vol. 9, pp. 733-740, Obesity, Silver Spring, Md., C1

journal

AFLP fingerprinting of the human genome

M Prochazka, K Walder, J Xia

(2001), Vol. 108, pp. 59-65, Human genetics, Berlin, Germany, C1-1

journal
2000

Impact of obesity and leptin treatment on adipocyte gene expression in Psammomys obesus

A Sanigorski, D Cameron-Smith, P Lewandowski, K Walder, A de Silva, G Morton, G Collier

(2000), Vol. 164, pp. 45-50, Journal of endocrinology, Bristol, England, C1-1

journal

Beacon: a novel gene involved in the regulation of energy balance

G Collier, J McMillan, K Windmill, K Walder, J Tenne-Brown, A de Silva, J Trevaskis, S Jones, G Morton, S Lee, G Augert, A Civitarese, P Zimmet

(2000), Vol. 49, pp. 1766-1771, Diabetes, Arlington, Va., C1-1

journal

Leptin and the treatment of obesity

K Walder, A De Silva

(2000), Vol. 51, pp. 66-79, Drug Development Research, Hoboken, N.J., C1-1

journal
1999

Leptin resistance in a polygenic, hyperleptinemic animal model of obesity and NIDDM: Psammomys obesus

K Walder, P Lewandowski, G Morton, A Sanigorski, P Zimmet, G Collier

(1999), Vol. 23, pp. 83-89, International Journal of Obesity, C1-1

journal
1998

Dysregulation of leptin in response to fasting in insulin-resistant Psammomys obesus (Israeli sand rats)

K Walder, S Lee, P Zimmet, G Collier

(1998), Vol. 47, pp. 125-128, Metabolism, Amsterdam, The Netherlands, C1-1

journal

Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians

K Walder, R Norman, R Hanson, P Schrauwen, M Neverova, C Jenkinson, J Easlick, C Warden, C Pecqueur, S Raimbault, D Ricquier, M Harper, K Silver, A Shuldiner, G Solanes, B Lowell, W Chung, R Leibel, R Pratley, E Ravussin

(1998), Vol. 7, pp. 1431-1435, Human molecular genetics, London, Eng., C1-1

journal
1997

Leptin and the development of obesity and diabetes in psammomys obesus

G Collier

(1997), Vol. 5, pp. 455-458, Obesity Research, C1-1

journal

Disproportionate increase of fatty acid binding proteins in the livers of obese diabetic Psammomys obesus

P Lewandowski, D Cameron-Smith, K Moulton, K Walder, A Sanigorski, G Collier

(1997), Vol. 827, pp. 536-540, Annals of the New York academy of sciences, Hoboken, N. J., C1-1

journal

The effect of dietary energy restriction on body weight gain and the development of noninsulin-dependent diabetes mellitus (NIDDM) in Psammomys obesus

K Walder, C Dascaliuc, P Lewandowski, A Sanigorski, P Zimmet, G Collier

(1997), Vol. 5, pp. 193-200, Obesity Research, C1-1

journal

Development of obesity and insulin resistance in the Israeli sand rat (Psammomys obesus). Does leptin play a role?

G Collier, A De Silva, A Sanigorski, K Walder, A Yamamoto, P Zimmet

(1997), Vol. 827, pp. 50-63, Annals of the New York Academy of Sciences, Chichester, Eng., C1-1

journal

Ob (obese) gene expression and leptin levels in Psammomys obesus

K Walder, M Willet, P Zimmet, G Collier

(1997), Vol. 1354, pp. 272-278, Biochimica et biophysica acts, Amsterdam, The Netherlands, C1-1

journal

Non-insulin dependent diabetes mellitus in Psammomys obesus is independent of changes in tissue fatty acid composition

G Collier, F Collier, A Sanigorski, K Walder, D Cameron-Smith, A Sinclair

(1997), Vol. 32, pp. 317-322, Lipids, Berlin, Germany, C1-1

journal
1995

Effect of coingestion of fat and protein with carbohydrate feedings on muscle glycogen storage

L Burke, G Collier, S Beasley, P Davis, P Fricker, P Heeley, K Walder, M Hargreaves

(1995), Vol. 78, pp. 2187-2192, Journal of applied physiology, Bethesda, Md., C1-1

journal

Funded Projects at Deakin

Australian Competitive Grants

Characterisation of chemerin as a novel adipokine associated with obesity and metabolic syndrome

Prof Ken Walder, Dr Jeremy Jowett

DART Grant - Research - Diabetes Australia - Victoria (Research Trust)

  • 2008: $22,274
  • 2007: $22,274

Enzymatic synthesis, microencapsulation and biological evaluation of a new class of omega-3 derived functional food ingredients

Prof Colin Barrow, Prof Ken Walder, Dr Jaroslav Kralovec, Dr Jacqui Francis, Prof Leigh Ackland, Dr Ian Musgrave, Dr Wei Zhang

ARC_DUAPAI ARC_Deakin University Australian Postgraduate Award Industry, ARC Linkage - Projects Rnd 1

  • 2013: $14,921
  • 2012: $183,043
  • 2011: $159,949
  • 2010: $153,111

Antidiabetic effects of a new secreted protein associated with type 2 diabetes

Prof Ken Walder

DART Grant - Research - Diabetes Australia - Victoria (Research Trust)

  • 2009: $26,054
  • 2008: $26,054

Discovery and development of novel insulin sensitising compounds for the treatment of Type 2 diabetes

Prof Ken Walder, A/Prof Fred Pfeffer, Dr Nicky Konstantopoulos, Dr Guy Krippner

ARC Linkage - Projects Rnd 1

  • 2012: $139,973
  • 2011: $88,130
  • 2010: $86,763

The role of amyloid beta in insulin resistance

A/Prof Sean Mcgee, Prof Ken Walder, Prof Mark Hargreaves

NHMRC Project Grant

  • 2014: $125,826
  • 2013: $138,472
  • 2012: $136,023

Understanding the role of class IIa histone deacetylases in metabolic disease

A/Prof Sean Mcgee, Prof Ken Walder

NHMRC Project Grant

  • 2014: $164,086
  • 2013: $161,714
  • 2012: $143,600

Threats of avian pathogens to endangered parrots and human health: developing and utilizing tools for risk reduction

Prof Andy Bennett, A/Prof Shane Raidal, Prof Marcel Klaassen, Prof Kate Buchanan, Prof Ken Walder, Dr Michael Magrath, Dr Yonatan Segal, Prof Martyn Jeggo

ARC Linkage - Projects

  • 2017: $54,016
  • 2016: $105,523
  • 2015: $112,909
  • 2014: $60,397

Gene Expression Signature Technology to Repurpose Drugs for Bipolar Disorder

Prof Ken Walder, Prof Michael Berk, Prof Marion Leboyer, Prof Brian Dean

NHMRC Project Grant

  • 2017: $157,493
  • 2016: $207,762
  • 2015: $117,544

The role of GAPDH acetylation and HDAC6 in liver metabolism and type 2 diabetes

A/Prof Sean Mcgee, A/Prof Clinton Bruce, Prof Forest White, Prof Ken Walder

NHMRC Project Grant

  • 2019: $215,274
  • 2018: $181,879
  • 2017: $169,227

CREDIT: The CRE for the Development of Innovative Therapies for Psychiatric Disorders

Prof Michael Berk, Prof John McGrath, Prof Patrick McGorry, Prof John McNeil, Prof Gin Malhi, Prof Felice Jacka, A/Prof Susan Cotton, Prof Ken Walder, A/Prof Olivia Dean, A/Prof Lana Williams

NHMRC - Centres of Research Excellence

  • 2019: $425,287

Other Public Sector Funding

Global Gene Expression Analysis of 10 rat colon tissue samples

Prof Ken Walder

  • 2009: $16,666

Tissue distribution of RIPTAC in mice.

Prof Ken Walder

  • 2010: $18,000

Determination of RIPTAC bioavailability, pharmacokinetics and distribution

Prof Ken Walder, Mr Timothy Connor, Ms Briana Spolding

  • 2011: $12,000

Delivery of MIRNA Using Genetically Modified Influenza Virus

Prof John Stambas, Prof Alister Ward, Prof Ken Walder, Ms Yingju Xia

  • 2014: $60,000

Threats of avian pathogens to endangered parrots and human health: developing and utilizing tools for risk reduction

Prof Andy Bennett, A/Prof Shane Raidal, Prof Marcel Klaassen, Prof Kate Buchanan, Prof Ken Walder, Dr Michael Magrath, Dr Yonatan Segal, Prof Martyn Jeggo

  • 2017: $25,000
  • 2016: $25,000
  • 2015: $30,000

Flourescent Cell Imager

Prof Ken Walder

  • 2014: $18,900

NHMRC Equipment Grant 2016

Prof Michael Berk, Prof Ken Walder

  • 2016: $17,691

Industry and Other Funding

Positional Candidate Genes Affecting Metabolic Syndrome

Dr Ahmed Kissebah, Prof Ken Walder

  • 2008: $83,444
  • 2007: $123,502
  • 2006: $96,944

Anti-inflammatory activity of mussel oil

Prof Ken Walder

  • 2009: $4,700

Enzymatic synthesis, microencapsulation and biological evaluation of a new class of omega-3 derived functional food ingredients

Prof Colin Barrow, Prof Ken Walder, Dr Jaroslav Kralovec, Dr Jacqui Francis, Prof Leigh Ackland, Dr Ian Musgrave, Dr Wei Zhang

  • 2012: $70,607
  • 2011: $53,835
  • 2010: $52,910

Novel Therapies for the Treatment of Obesity

Prof Ken Walder

  • 2008: $2,133,334
  • 2007: $2,400,000
  • 2006: $2,420,000

Mechanism of action of VVP808

Prof Ken Walder

  • 2010: $17,740
  • 2009: $180,000

Effects of novel insulin formulations on glucose homeostasis in streptozotocin-treated diabetic rats

Prof Ken Walder

  • 2009: $72,500
  • 2008: $72,500

Discovery and development of novel insulin sensitising compounds for the treatment of Type 2 diabetes

Prof Ken Walder, A/Prof Fred Pfeffer, Dr Nicky Konstantopoulos, Dr Guy Krippner

  • 2012: $127,200
  • 2011: $174,725
  • 2010: $146,043

Development of a rat model of acute pancreatitis

Prof Ken Walder

  • 2009: $80,000

Expression of Galanin receptors in Mouse, Rat and Human Pancreas

Prof Ken Walder

  • 2010: $6,500
  • 2009: $6,500

Effects of novel insulin formulations on glucose homeostasis in streptozotocin-treated diabetic rats

Prof Ken Walder

  • 2010: $72,500

Effects of amylin and leptin in sand rats

Prof Ken Walder

  • 2010: $36,132

Effects of novel insulin formulations on body weight and glucose homeostasis in Psammomy obesus

Prof Ken Walder

  • 2010: $17,000

New studies to investigate efficacy and safety of VVP808 (Part A)

Prof Ken Walder, Dr Nicky Konstantopoulos, Mr Scott Lee

  • 2011: $90,000

Investigate and characterise VVP808 interacting proteins (Part B)

Prof Ken Walder

  • 2013: $8,681
  • 2012: $230,000
  • 2011: $160,000

VVP100X - Research Program: Novel analogues for the treatment of type 2 diabetes

Prof Ken Walder

  • 2012: $280,000
  • 2011: $70,000

The genetic basis of mercury sensitivity in pink disease survivors

Prof David Austin, Prof Ken Walder, Ms Shakuntla Gondalia, Kerrie Shandley, A/Prof Enzo Palombo, Dr Simon Knowles, Mr Matthew Garrecht

  • 2014: $9,074
  • 2013: $25,720
  • 2012: $18,389

Effects of novel insulin formulations on glucose homeostasis in streptozotocin-treated diabetic rats

Prof Ken Walder

  • 2014: $6,727
  • 2013: $6,727

Effects of encapsulation on bioavailability and distribution of orally administered milk lipid formulations

Prof Ken Walder

  • 2017: $15,000
  • 2016: $82,899
  • 2014: $12,633

Beak and Feather Disease Virus in wild avian populations in Australia

Prof Andy Bennett, Dr Mathew Berg, Prof Ken Walder, Ms Johanne (Hanne) Marie Martens

  • 2019: $5,100
  • 2017: $4,800
  • 2016: $5,900

Other Funding Sources

Field-emission gun transmission electron microscope for the research in nanomaterials, metal alloys and biological sciences

Prof Ying (Ian) Chen, Prof Matthew Barnett, Prof Peter Hodgson, Prof Xungai Wang, Dr Takuya Tsuzuki, Dr Cui'E Wen, Dr Alexey Glushenkov, Prof Lingxue Kong, Prof Charles Sorrell, Dr Yuebin Zhang, Prof Vicki Chen, Dr Dominic Phelan, Prof Ken Walder, Dr Germanas Peleckis, A/Prof Simon Moulton, Prof John Beynon, Dr Xiaolin Wang, Prof David Cahill, Dr Pavel Cizek, Prof Neil Barnett, A/Prof Nicole Stanford, Prof Qipeng Guo

  • 2011: $230,000

NHMRC Equipment Grant 2017 - RTCA iCELLigence instrument

Prof Ken Walder

  • 2018: $29,584

Neon Open System Electroporator

Prof Ken Walder, Prof Michael Berk

  • 2019: $11,347

Supervisions

Principal Supervisor
2018

Srisaiyini Kidnapillai

Thesis entitled: Molecular Mechanisms of Action of Drugs Used to Treat Bipolar Disorder

Doctor of Philosophy (Medicine), School of Medicine

2017

Christopher Kintakas

Thesis entitled: ADAMTS5 expression and function in myoblast fusion and muscle regeneration

Doctor of Philosophy (Medicine), School of Medicine

2015

Sugeetha Ramakrishnan

Thesis entitled: The relationship between milk, mammary adipocytes and ECM in regulating murine mammary gland involution

Doctor of Philosophy (Medicine), School of Medicine

Vengama Naidu Modepalli

Thesis entitled: The Marsupial: A unique model for understanding the regulation of lung development

Doctor of Philosophy (Medicine), School of Medicine

Ashalyn Watt

Thesis entitled: Innate immunity in the breast and the role of the milk peptidome

Doctor of Philosophy (Medicine), School of Medicine

2013

Bradley Hayward

Thesis entitled: A Global Approach to Dissecting Lipid-induced Impairment of Liver Gluconeogenesis

Doctor of Philosophy (Medicine), School of Medicine

2011

Richard Bayles

Thesis entitled: A Genetic and Epigenetic Analysis of the Noradrenaline Transporter

Doctor of Philosophy (Medicine), School of Medicine

2010

Lyndal Jane Bayles

Thesis entitled: Mitochondrial Target Discovery in Diabetic Skeletal Muscle

Doctor of Philosophy (Medicine), School of Medicine

2008

Fiona Collier

Thesis entitled: Rhotekin 2, a Novel GTPase Effector Involved in Resistance to Apoptosis

Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences

Kiymet Bozaoglu

Thesis entitled: Metabolically Important Secreted Proteins in Psammomys obesus

Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences

Matthew Prior

Thesis entitled: AHI-I and NDRG2 Function in Skeletal Muscle and the Development of Type 2 Diabetes

Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences

Kristy Bolton

Thesis entitled: Novel Secreted Proteins Involved in Obesity and Type 2 Diabetes

Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences

2007

Subhadhcha Poonsatha

Thesis entitled: Identification and Characterisation of Novel Compound(s) for the Treatment of Type 2 Diabetes

Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences

Associate Supervisor
2019

Smithamol Sithara

Thesis entitled: A beta-cell specific global approach for drug identification in Type 2 Diabetes

Doctor of Philosophy (Medicine), School of Medicine

Shauna Seneviratne

Thesis entitled: The effects of Ficolin and the Fibrinogen-like domain on ex vivo hematopoietic stem cell expansion.

Doctor of Philosophy (Biol & Chem), Institute for Frontier Materials

2018

Kirstie Anne De Jong

Thesis entitled: Characterisation of the Obese and T2D Heart - Protein Kinase D, a Possible Therapeutic Target

Doctor of Philosophy (Medicine), School of Medicine

2017

Kyoko Hasebe

Thesis entitled: Investigating Neurobiological Mechanisms Linking Depression and Inflammation

Doctor of Philosophy (Medicine), School of Medicine

Parminder Kaur Ajji

Thesis entitled: Functional characterization of a novel ribosome inactivating protein from Momordica balsamina

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

2016

Rajas Kale

Thesis entitled: Developing Neurostimulation Techniques to Investigate Antidepressant and Mood Modulating Behaviors

Doctor of Philosophy (Engineering), School of Engineering

Aung Kyaw Soe

Thesis entitled: A Modular Design Framework for Lab-On-a-Chips

Doctor of Philosophy (Information Technology), Institute for Intelligent Systems Research and Innovation

Simon Bond

Thesis entitled: The Role of Glyceraldehyde-3-Phosphate Dehydrogenase Acetylation in Liver Metabolism

Doctor of Philosophy (Medicine), School of Medicine

2015

Daniel Fraher

Thesis entitled: Chemical Modulators of Lipid Abundance and Bone Development

Doctor of Philosophy (Medicine), School of Medicine

Anand Khedkar

Thesis entitled: Development and Evaluation of a Novel Insulin Analogue

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Rajneesh Chaudhary

Thesis entitled: Zinc doped ferrite magnetic resonance imaging contrast agent for atherosclerosis

Doctor of Philosophy (Medicine), School of Medicine

Justin Eastwood

Thesis entitled: The Ecology and Evolution of Beak and Feather Disease Virus in Platycercus elegans

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

Juliane Czeczor

Thesis entitled: Functional Role of Amyloid b42 in Systemic Glucose Metabolism

Doctor of Philosophy (Medicine), School of Medicine

2014

Vidhi Gaur

Thesis entitled: HDAC inhibition as a therapeutic potential to treat metabolic diseases

Doctor of Philosophy (Medicine), School of Medicine

2013

Bingshan Li

Thesis entitled: Production and Characterisation of Powdered Fibrous Materials

Doctor of Philosophy (Engineering), Institute for Frontier Materials

2004

James Trevaskis

Thesis entitled: Novel Hypothalamic Genes Involved in Body Weight Regulation in Psammomys obesus

Doctor of Philosophy, School of Exercise and Nutrition Sciences

2002

Anthony Civitarese

Thesis entitled: Novel Genes in the Muscle of Obese-Diabetic Psammomys obesus

Doctor of Philosophy (Nutrition & Exercise) (Low Cost), School of Health Sciences

Adam Southon

Thesis entitled: Novel Genes in the Liver of Diabetic Psammomys obesus

Master of Science, School of Health Sciences