Dr Matthew McKenzie

MicroRNA-101-3p Modulates Mitochondrial Metabolism via the Regulation of Complex II Assembly

Mark Ziemann, Sze Lim, Yilin Kang, Sona Samuel, Isabel Sanchez, Michael Gantier, Diana Stojanovski, Matthew McKenzie

(2022), Vol. 434, pp. 1-16, Journal of Molecular Biology, Amsterdam, The Netherlands, C1

The Effects of in Utero Fetal Hypoxia and Creatine Treatment on Mitochondrial Function in the Late Gestation Fetal Sheep Brain

A Muccini, N Tran, N Hale, M McKenzie, R Snow, D Walker, S Ellery

(2022), Vol. 2022, pp. 1-19, Oxidative Medicine and Cellular Longevity, Cairo, Egypt, C1

Loss of mitochondrial fatty acid β-oxidation protein short-chain Enoyl-CoA hydratase disrupts oxidative phosphorylation protein complex stability and function

H Burgin, A Sharpe, S Nie, M Ziemann, J Crameri, D Stojanovski, J Pitt, A Ohtake, K Murayama, M McKenzie

(2022), pp. 1-22, FEBS Journal, London, Eng., C1

Stimulating Mitochondrial Biogenesis with Deoxyribonucleosides Increases Functional Capacity in ECHS1-Deficient Cells

Harrison Burgin, Jordan Crameri, Diana Stojanovski, M Sanchez, Mark Ziemann, Matthew McKenzie

(2022), Vol. 23, pp. 1-19, International Journal of Molecular Sciences, Basel, Switzerland, C1

Integrating mitochondrial aerobic metabolism into ecology and evolution

Rebecca Koch, Katherine Buchanan, Stefania Casagrande, Ondi Crino, Damian Dowling, Geoffrey Hill, Wendy Hood, Matthew McKenzie, Mylene Mariette, Daniel Noble, Alexandra Pavlova, Frank Seebacher, Paul Sunnucks, Eve Udino, Craig White, Karine Salin, Antoine Stier

(2021), Vol. 36, pp. 321-332, Trends in Ecology & Evolution, Oxford, Eng., C1

Prenatal acoustic programming of mitochondrial function for high temperatures in an arid-adapted bird

E Udino, J George, M McKenzie, A Pessato, O Crino, K Buchanan, M Mariette

(2021), Vol. 288, Proceedings of the Royal Society B: Biological Sciences, England, C1

Understanding the role of OXPHOS dysfunction in the pathogenesis of ECHS1 Deficiency

Harrison Burgin, Matthew McKenzie

(2020), Vol. 594, pp. 590-610, FEBS Letters, Chichester, Eng., C1

Pioglitazone and deoxyribonucleoside combination treatment increases mitochondrial respiratory capacity in m.3243A>G MELAS cybrid cells

H Burgin, M Sanchez, C Smith, I Trounce, M McKenzie

(2020), Vol. 21, International Journal of Molecular Sciences, Switzerland, C1

Assessment of the web-based audience response system socrative for biomedical science revision classes

Matthew McKenzie, Mark Ziemann

(2020), pp. 1-6, International Journal of Educational Research Open, Amsterdam, The Netherlands, C1

Nuclear response to divergent mitochondrial DNA genotypes modulates the interferon immune response

M Lopez Sanchez, M Ziemann, A Bachem, R Makam, J Crowston, C Pinkert, M McKenzie, S Bedoui, I Trounce

(2020), Vol. 15, pp. e0239804-, PloS one, United States, C1

Most clinical anti-EGFR antibodies do not neutralize both wtEGFR and EGFRvIII activation in glioma

S Greenall, M McKenzie, E Seminova, O Dolezal, L Pearce, J Bentley, M Kuchibhotla, S Chen, K McDonald, H Kornblum, R Endersby, T Adams, T Johns

(2019), Vol. 21, pp. 1016-1027, Neuro-Oncology, England, C1

Loss of the Mitochondrial Fatty Acid β-Oxidation Protein Medium-Chain Acyl-Coenzyme A Dehydrogenase Disrupts Oxidative Phosphorylation Protein Complex Stability and Function

S Lim, M Tajika, M Shimura, K Carey, D Stroud, K Murayama, A Ohtake, M McKenzie

(2018), Vol. 8, Scientific Reports, England, C1-1

Mitochondrial fatty acid oxidation disorders associated with short-chain enoyl-CoA hydratase (ECHS1) deficiency

A Sharpe, M McKenzie

(2018), Vol. 7, Cells, Switzerland, C1-1

Monocytes and dendritic cells are the primary sources of interleukin 37 in human immune cells

Ina Rudloff, Steven Cho, Jason Lao, Devi Ngo, Matthew McKenzie, Claudia Nold-Petry, Marcel Nold

(2017), Vol. 101, pp. 901-911, Journal of leukocyte biology, Chichester, Eng., C1-1

Simultaneous measurement of mitochondrial calcium and mitochondrial membrane potential in live cells by fluorescent microscopy

M McKenzie, S Lim, M Duchen

(2017), Vol. 2017, Journal of Visualized Experiments, United States, C1-1

Mitochondrial DNA haplotypes induce differential patterns of DNA methylation that result in differential chromosomal gene expression patterns

W Lee, X Sun, T Tsai, J Johnson, J Gould, D Garama, D Gough, M McKenzie, I Trounce, J St. John

(2017), Vol. 3, Cell Death Discovery, United States, C1-1

Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability

Y Kang, M Baker, M Liem, J Louber, M McKenzie, I Atukorala, C Ang, S Keerthikumar, S Mathivanan, D Stojanovski

(2016), Vol. 5, eLife, England, C1-1

Loss of mitochondrial DNA-encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly

S Lim, J Hroudová, N Van Bergen, M Lopez Sanchez, I Trounce, M McKenzie

(2016), Vol. 30, pp. 2236-2248, FASEB Journal, United States, C1-1

Dietary interventions designed to protect the perinatal brain from hypoxic-ischemic encephalopathy - Creatine prophylaxis and the need for multi-organ protection

S Ellery, H Dickinson, M McKenzie, D Walker

(2016), Vol. 95, pp. 15-23, Neurochemistry International, England, C1-1

Impaired cellular bioenergetics causes mitochondrial calcium handling defects in MT-ND5 mutant cybrids

M McKenzie, M Duchen

(2016), Vol. 11, PLoS ONE, United States, C1-1

Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency

G Cagnone, T Tsai, Y Makanji, P Matthews, J Gould, M Bonkowski, K Elgass, A Wong, L Wu, M McKenzie, D Sinclair, J John

(2016), Vol. 6, Scientific Reports, England, C1-1

Combined defects in oxidative phosphorylation and fatty acid β-oxidation in Mitochondrial disease

A Nsiah-Sefaa, M McKenzie

(2016), Vol. 36, Bioscience Reports, England, C1-1

AarF domain containing kinase 3 (ADCK3) mutant cells display signs of oxidative stress, defects in mitochondrial homeostasis and lysosomal accumulation

J Cullen, N Murad, A Yeo, M McKenzie, M Ward, K Chong, N Schieber, R Parton, Y Lim, E Wolvetang, G Maghzal, R Stocker, M Lavin

(2016), Vol. 11, PLoS ONE, United States, C1-1

Deletion of the Complex I Subunit NDUFS4 Adversely Modulates Cellular Differentiation

J Johnson, W Lee, A Frazier, V Vaghjiani, A Laskowski, A Rodriguez, G Cagnone, M McKenzie, S White, D Nisbet, D Thorburn, J St. John

(2016), Vol. 25, pp. 239-250, Stem Cells and Development, United States, C1-1

Characterization of mitochondrial FOXRED1 in the assembly of respiratory chain complex I

Luke Formosa, Masakazu Mimaki, Ann Frazier, Matthew McKenzie, Tegan Stait, David Thorburn, David Stroud, Michael Ryan

(2015), Vol. 24, pp. 2952-2965, Human molecular genetics, Oxford, Eng., C1-1

Anti-cancer analogues ME-143 and ME-344 exert toxicity by directly inhibiting mitochondrial NADH: Ubiquinone oxidoreductase (Complex I)

S Lim, K Carey, M McKenzie

(2015), Vol. 5, pp. 689-701, American Journal of Cancer Research, Madison, Wis., C1-1

A founder mutation in PET100 causes isolated complex IV deficiency in Lebanese individuals with Leigh syndrome

Sze Lim, Katherine Smith, David Stroud, Alison Compton, Elena Tucker, Ayan Dasvarma, Luke Gandolfo, Justine Marum, Matthew McKenzie, Heidi Peters, David Mowat, Peter Procopis, Bridget Wilcken, John Christodoulou, Garry Brown, Michael Ryan, Melanie Bahlo, David Thorburn

(2014), Vol. 94, pp. 209-222, American Journal of Human Genetics, Amsterdam, The Netherlands, C1-1

The identification of mitochondrial DNA variants in glioblastoma multiforme

Ka Yeung, Adam Dickinson, Jacqueline Donoghue, Galina Polekhina, Stefan White, Dimitris Grammatopoulos, Matthew McKenzie, Terrance Johns, Justin St John

(2014), Vol. 2, pp. 1-21, Acta neuropathologica communications, London, England, C1-1

Capture of somatic mtDNA point mutations with severe effects on oxidative phosphorylation in synaptosome cybrid clones from human brain

Matthew McKenzie, Maria Chiotis, Jana Hroudová, Maria Lopez Sanchez, Sze Lim, Mark Cook, Penny McKelvie, Richard Cotton, Michael Murphy, Justin St John, Ian Trounce

(2014), Vol. 35, pp. 1476-1484, Human mutation, London, Eng., C1-1

Mitochondrial DNA haplotypes define gene expression patterns in pluripotent and differentiating embryonic stem cells

Richard Kelly, Andrew Rodda, Adam Dickinson, Arsalan Mahmud, Christian Nefzger, William Lee, John Forsythe, Jose Polo, Ian Trounce, Matthew McKenzie, David Nisbet, Justin St John

(2013), Vol. 31, pp. 703-716, Stem cells, Chichester, Eng., C1-1

The effects of nuclear reprogramming on mitochondrial DNA replication

Richard Kelly, Huseyin Sumer, Matthew McKenzie, Joao Facucho-Oliveira, Ian Trounce, Paul Verma, Justin St John

(2013), Vol. 9, pp. 1-15, Stem cell reviews and reports, Cham, Switzerland, C1-1

The regulation of mitochondrial DNA copy number in glioblastoma cells

A Dickinson, K Yeung, J Donoghue, M Baker, R Kelly, M McKenzie, T Johns, J St John

(2013), Vol. 20, pp. 1644-1653, Cell death & differentiation, London, Eng., C1-1

Mitochondrial dysfunction in a novel form of autosomal recessive ataxia

Nor Murad, Jason Cullen, Matthew McKenzie, Michael Ryan, David Thorburn, Nuri Gueven, Junya Kobayashi, Geoff Birrell, Jian Yang, Thilo Dörk, Olivier Becherel, Padraic Grattan-Smith, Martin Lavin

(2013), Vol. 13, pp. 235-245, Mitochondrion, Amsterdam, The Netherlands, C1-1

Modulation of ceramide-induced cell death and superoxide production by mitochondrial DNA-encoded respiratory chain defects in Rattus xenocybrid mouse cells

Ian Trounce, Peter Crouch, Kirstyn Carey, Matthew McKenzie

(2013), Vol. 1827, pp. 817-825, Biochimica et biophysica acta (BBA) - bioenergetics, Amsterdam, The Netherlands, C1-1

Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A

Richard Kelly, Arsalan Mahmud, Matthew McKenzie, Ian Trounce, Justin St John

(2012), Vol. 40, pp. 10124-10138, Nucleic acids research, Oxford, Eng., C1-1

Next-generation sequencing in molecular diagnosis: NUBPL mutations highlight the challenges of variant detection and interpretation

Elena Tucker, Masakazu Mimaki, Alison Compton, Matthew McKenzie, Michael Ryan, David Thorburn

(2012), Vol. 33, pp. 411-418, Human mutation, Chichester, Eng., C1-1

Proteomic and metabolomic analyses of mitochondrial complex I-deficient mouse model generated by spontaneous B2 short interspersed nuclear element (SINE) insertion into NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) gene

Dillon Leong, Jasper Komen, Chelsee Hewitt, Estelle Arnaud, Matthew McKenzie, Belinda Phipson, Melanie Bahlo, Adrienne Laskowski, Sarah Kinkel, Gayle Davey, William Heath, Anne Voss, René Zahedi, James Pitt, Roman Chrast, Albert Sickmann, Michael Ryan, Gordon Smyth, David Thorburn, Hamish Scott

(2012), Vol. 287, pp. 20652-20663, Journal of biological chemistry, Rockville, Md., C1-1

Understanding mitochondrial complex I assembly in health and disease

Masakazu Mimaki, Xiaonan Wang, Matthew McKenzie, David Thorburn, Michael Ryan

(2012), Vol. 1817, pp. 851-862, Biochimica et biophysica acta (BBA) - bioenergetics, Amsterdam, The Netherlands, C1-1

Mutations in the gene encoding C8orf38 block complex I assembly by inhibiting production of the mitochondria-encoded subunit ND1

Matthew McKenzie, Elena Tucker, Alison Compton, Michael Lazarou, Christa George, David Thorburn, Michael Ryan

(2011), Vol. 414, pp. 413-426, Journal of molecular biology, London, Eng., C1-1

Mutations in MTFMT underlie a human disorder of formylation causing impaired mitochondrial translation

Elena Tucker, Steven Hershman, Caroline Köhrer, Casey Belcher-Timme, Jinal Patel, Olga Goldberger, John Christodoulou, Jonathon Silberstein, Matthew McKenzie, Michael Ryan, Alison Compton, Jacob Jaffe, Steven Carr, Sarah Calvo, Uttam RajBhandary, David Thorburn, Vamsi Mootha

(2011), Vol. 14, pp. 428-434, Cell metabolism, Amsterdam, The Netherlands, C1-1