Dr Nicole Stupka

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2018

Large and small assembly: combining functional macromolecules with small peptides to control the morphology of skeletal muscle progenitor cells

R Li, N McRae, D McCulloch, M Boyd-Moss, C Barrow, D Nisbet, N Stupka, R Williams

(2018), Vol. 19, pp. 825-837, Biomacromolecules, Washington, D.C., C1

journal

The ADAMTS5 metzincin regulates zebrafish somite differentiation

Carolyn Dancevic, Yann Gibert, Joachim Berger, Adam Smith, Clifford Liongue, Nicole Stupka, Alister Ward, Daniel McCulloch

(2018), Vol. 19, pp. 1-12, International journal of molecular sciences, Basel, Switzerland, C1

journal

Emerging roles of endoplasmic reticulum-resident selenoproteins in the regulation of cellular stress responses and the implications for metabolic disease

Alex Addinsall, Craig Wright, Sof Andrikopoulos, Chris van der Poel, Nicole Stupka

(2018), Vol. 475, pp. 1037-1057, Biochemical journal, London, Eng., C1

journal

Deficiency of selenoprotein S, an endoplasmic reticulum resident oxidoreductase, impairs the contractile function of fast-twitch hindlimb muscles

Alex Addinsall, Craig Wright, Chris Shaw, Natasha McRae, Leonard Forgan, Chia-Heng Weng, Xavier Conlan, Paul Francis, Zoe Smith, Sofianos Andrikopoulos, Nicole Stupka

(2018), Vol. 315, pp. R380-R396, American journal of physiology-regulatory, integrative and comparative physiology, Bethesda, Md., C1

journal

Differential regulation of cellular stress responses by the endoplasmic reticulum-resident Selenoprotein S (Seps1) in proliferating myoblasts versus myotubes

Alex Addinsall, Sheree Martin, Fiona Collier, Xavier Conlan, Victoria Foletta, Nicole Stupka

(2018), Vol. 6, pp. 1-15, Physiological reports, Chichester, Eng., C1

journal
2017

A reduction in selenoprotein S amplifies the inflammatory profile of fast-twitch skeletal muscle in the mdx dystrophic mouse

C Wright, G Allsopp, A Addinsall, N McRae, S Andrikopoulos, N Stupka

(2017), Vol. 2017, pp. 1-12, Mediators of inflammation, Cairo, Egypt, C1

journal

Glucocorticoids improve myogenic differentiation in vitro by suppressing the synthesis of versican, a transitional matrix protein overexpressed in dystrophic skeletal muscles

N McRae, L Forgan, B McNeill, A Addinsall, D McCulloch, C Van der Poel, N Stupka

(2017), Vol. 18, pp. 1-22, International journal of molecular sciences, Basel, Switzerland, C1

journal
2016

Characterisation of minimalist co-assembled fluorenylmethyloxycarbonyl self-assembling peptide systems for presentation of multiple bioactive peptides

C Horgan, A Rodriguez, R Li, K Bruggeman, N Stupka, J Raynes, L Day, J White, R Williams, D Nisbet

(2016), Vol. 38, pp. 11-22, Acta biomaterialia, Amsterdam, The Netherlands, C1

journal
2015

Sarcopenia and the common mental disorders: a potential regulatory role of skeletal muscle on brain function?

J Pasco, L Williams, F Jacka, N Stupka, S Brennan-Olsen, K Holloway, M Berk

(2015), Vol. 13, pp. 351-357, Current Osteoporosis Reports, New York, N.Y., C1

journal
2013

Versican processing by a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats proteinases-5 and-15 facilitates myoblast fusion

N Stupka, C Kintakas, J White, F Fraser, M Hanciu, N Aramaki-Hattori, S Martin, C Coles, F Collier, A Ward, S Apte, D McCulloch

(2013), Vol. 288, pp. 1907-1917, Journal of Biological Chemistry, C1

journal

Biosynthesis and expression of a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats-15: A novel versican-cleaving proteoglycanase

C Dancevic, F Fraser, A Smith, N Stupka, A Ward, D McCulloch

(2013), Vol. 288, pp. 37267-37276, Journal of Biological Chemistry, C1

journal
2011

Determination of intracellular glutathione and glutathione disulfide using high performance liquid chromatography with acidic potassium permanganate chemiluminescence detection

G McDermott, P Francis, K Holt, K Scott, S Martin, N Stupka, N Barnett, X Conlan

(2011), Vol. 136, pp. 2578-2585, Analyst, C1

journal
2010

Determination of intracellular glutathione and cysteine using HPLC with a monolithic column after derivatization with monobromobimane

X Conlan, N Stupka, G McDermott, P Francis, N Barnett

(2010), Vol. 24, pp. 455-457, Biomedical Chromatography, C1

journal

Correlation between acidic potassium permanganate chemiluminescence and in vitro cell culture assay: Physiologically meaningful antioxidant activity

X Conlan, N Stupka, G McDermott, N Barnett, P Francis

(2010), Vol. 2, pp. 171-173, Analytical Methods, C1

journal
2009

NDRG2, a novel regulator of myoblast proliferation, is regulated by anabolic and catabolic factors

V Foletta, M Prior, N Stupka, K Carey, D Segal, S Jones, C Swinton, S Martin, D Cameron-Smith, K Walder

(2009), Vol. 587, pp. 1619-1634, Journal of Physiology, C1

journal

Enhanced proliferation of human skeletal muscle precursor cells derived from elderly donors cultured in estimated physiological (5%) oxygen

S Martin, F Collier, M Kirkland, K Walder, N Stupka

(2009), Vol. 61, pp. 93-107, Cytotechnology, C1

journal
2008

Stimulation of calcineurin A? activity attenuates muscle pathophysiology in mdx dystrophic mice

N Stupka, J Schertzer, R Bassel-Duby, E Olson, G Lynch

(2008), Vol. 294, American Journal of Physiology - Regulatory Integrative and Comparative Physiology, C1-1

journal

Glucose and insulin modulate the expression and activity of the thioredoxin antioxidant system in cultured human skeletal muscle fibres

N Stupka, S Martin, J McKenzie, F Collier, N Konstantopoulos

(2008), pp. 1-1, AUPS 2008 : Proceedings of the Australian Physiological Society 2008, Melbourne, VIC, E1-1

conference

Effects of oxygen concentration on the cellular redox state and glutathione content of skeletal muscle cells in culture

N Stupka, X Conlan, S Martin, F Collier

(2008), Proceedings of the Australian Health and Medical Research Congress 2008, Brisbane, Queensland, E1-1

conference

Physiological (5%) oxygen levels enhance proliferation but not differentiation of human primary skeletal muscle precursor cells in vitro

S Martin, F Collier, N Stupka

(2008), Proceedings of the Australian Health and Medical Research Congress 2008, Brisbane, Queensland, E1-1

conference
2007

Calcineurin-A? activation enhances the structure and function of regenerating muscles after myotoxic injury

N Stupka, J Schertzer, R Bassel-Duby, E Olson, G Lynch

(2007), Vol. 293, American Journal of Physiology - Regulatory Integrative and Comparative Physiology, C1-1

journal
2006

Activated calcineurin ameliorates contraction-induced injury to skeletal muscles of mdx dystrophic mice

N Stupka, D Plant, J Schertzer, T Emerson, R Bassel-Duby, E Olson, G Lynch

(2006), Vol. 575, pp. 645-656, Journal of Physiology, C1-1

journal

Differential calcineurin signalling activity and regeneration efficacy in diaphragm and limb muscles of dystrophic mdx mice

N Stupka, B Michell, B Kemp, G Lynch

(2006), Vol. 16, pp. 337-346, Neuromuscular Disorders, C1-1

journal
2005

Interleukin-15 administration improves diaphragm muscle pathology and function in dystrophic mdx mice

L Harcourt, A Holmes, P Gregorevic, J Schertzer, N Stupka, D Plant, G Lynch

(2005), Vol. 166, pp. 1131-1141, American Journal of Pathology, C1-1

journal

?2-Agonist administration increases sarcoplasmic reticulum Ca2+-ATPase activity in aged rat skeletal muscle

J Schertzer, D Plant, J Ryall, F Beitzel, N Stupka, G Lynch

(2005), Vol. 288, American Journal of Physiology - Endocrinology and Metabolism, C1-1

journal
2004

Changes in contractile activation characteristics of rat fast and slow skeletal muscle fibres during regeneration

P Gregorevic, D Plant, N Stupka, G Lynch

(2004), Vol. 558, pp. 549-560, Journal of Physiology, C1-1

journal

The calcineurin signal transduction pathway is essential for successful muscle regeneration in mdx dystrophic mice

N Stupka, P Gregorevic, D Plant, G Lynch

(2004), Vol. 107, pp. 299-310, Acta Neuropathologica, C1-1

journal
2003

Substrate Utilization during Exercise Performed with and Without Glucose Ingestion in Female and Male Endurance-Trained Athletes

M Riddell, S Partington, N Stupka, D Armstrong, C Rennie, M Tarnopolsky

(2003), Vol. 13, pp. 407-421, International Journal of Sport Nutrition and Exercise Metabolism, C1-1

journal
2001

Cellular adaptation to repeated eccentric exercise-induced muscle damage

N Stupka, M Tarnopolsky, N Yardley, S Phillips

(2001), Vol. 91, pp. 1669-1678, Journal of Applied Physiology, C1-1

journal

Effects of ovariectomy and estrogen on ischemia-reperfusion injury in hindlimbs of female rats

N Stupka, P Tiidus

(2001), Vol. 91, pp. 1828-1835, Journal of Applied Physiology, C1-1

journal
2000

Gender differences in muscle inflammation after eccentric exercise

N Stupka, S Lowther, K Chorneyko, J Bourgeois, C Hogben, M Tarnopolsky

(2000), Vol. 89, pp. 2325-2332, Journal of Applied Physiology, C1-1

journal

Funded Projects at Deakin

Australian Competitive Grants

Type 2 diabetes and ageing-associated muscle atrophy: role of oxidative stress and redox sensitive signalling pathways

Dr Nicole Stupka

NHMRC - Training PD Award - Peter Doherty Fellowship

  • 2011: $17,180
  • 2010: $72,508
  • 2009: $71,250
  • 2008: $70,424
  • 2007: $68,500

Defining mechanisms underlying skeletal muscle development and muscular dystrophy

Dr Daniel Mcculloch, Dr Nicole Stupka, Prof Alister Ward

Financial Markets - Foundation for Children

  • 2012: $34,980
  • 2011: $71,230
  • 2010: $36,250

Industry and Other Funding

Role of SEPS1 in insulin resistance and type 2 diabetes

Dr Nicole Stupka

  • 2010: $15,000

Selenoprotein S (SEPS1): a novel gene for better muscle health and function?

Dr Nicole Stupka, Prof Julie Pasco, Dr Kiymet Bozaoglu

  • 2016: $30,000

Supervisions

Principal Supervisor
2019

Alex Bernard Addinsall

Thesis entitled: The Regulation of Skeletal Muscle Contractile Function by Selenoprotein S.

Doctor of Philosophy (Medicine), School of Medicine

2018

Natasha Lee McRae

Thesis entitled: Targeting versican as a therapeutic strategy in Duchenne muscular dystrophy

Doctor of Philosophy (Medicine), School of Medicine

Associate Supervisor
2016

Rui Li

Thesis entitled: Designing Self-Assembled Multicomponent Scaffolds for Regenerative Medicine

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences