Dr Richard Williams

STAFF PROFILE

Position

Senior Lecturer In Medical Biotechnology

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Qualifications

Doctor of Philosophy, University of Manchester, 2009
Master of Science, University of Birmingham, 2005
Bachelor of Science, University of Reading, 2001

Contact

Biography

Dr Williams, after stints at the Medical Research Council and the Forensic Science service, completed a PhD in Materials Science at the University of Manchester. He then took up a Postdoctoral Fellowship in the Biomaterials Theme of CSIRO Molecular and Health Technologies  in Melbourne Australia. Following that, he was awarded a prestigious Alfred Deakin Research Fellowship (2012-2014).

He is currently a Senior Lecturer in Medical Biotechnology in the School of Medicine.

Read more on Richard's profile

Research interests

Self Assembled Materials for regenerative medicine

Media appearances

https://www.sbs.com.au/news/seaweed-may-help-heal-injured-brain-tissue-australian-research-finds

https://www.youtube.com/watch?v=i2C4d34JXZ8

Publications

Filter by

2019

Rational design of additively manufactured Ti6Al4V implants to control Staphylococcus aureus biofilm formation

A Sarker, N Tran, A Rifai, M Brandt, P Tran, M Leary, K Fox, R Williams

(2019), Vol. 5, pp. 1-13, Materialia, Amsterdam, The Netherlands, C1

journal

Optimising the biocompatibility of 3D printed photopolymer constructs in vitro and in vivo

C Ngan, C O'Connell, R Blanchard, M Boyd-Moss, R Williams, J Bourke, A Quigley, P McKelvie, R Kapsa, P Choong

(2019), Vol. 14, pp. 1-12, Biomedical materials, Bristol, Eng., C1

journal
2018

Large and small assembly: combining functional macromolecules with small peptides to control the morphology of skeletal muscle progenitor cells

R Li, N McRae, D McCulloch, M Boyd-Moss, C Barrow, D Nisbet, N Stupka, R Williams

(2018), Vol. 19, pp. 825-837, Biomacromolecules, Washington, D.C., C1

journal

Scaffolds formed via the non-equilibrium supramolecular assembly of the synergistic ECM peptides RGD and PHSRN demonstrate improved cell attachment in 3D

S Aye, R Li, M Boyd-Moss, B Long, S Pavuluri, K Bruggeman, Y Wang, C Barrow, D Nisbet, R Williams

(2018), Vol. 10, pp. 1-13, Polymers, Basel, Switzerland, C1

journal

A programmed anti-inflammatory nanoscaffold (PAIN) as a 3D tool to understand the brain injury response

Francesca Maclean, Georgina Ims, Malcolm Horne, Richard Williams, David Nisbet

(2018), Vol. 30, pp. 1-8, Advanced materials, London, Eng., C1

journal

Nanostructured biomedical selenium at the biological interface (Review)

Victoria Tan, Angelica Hinchman, Richard Williams, Phong Tran, Kate Fox

(2018), Vol. 13, pp. 1-19, Biointerphases, New York, N.Y., C1

journal

Angle defines attachment: Switching the biological response to titanium interfaces by modifying the inclination angle during selective laser melting

A Sarker, N Tran, A Rifai, J Elambasseril, M Brandt, R Williams, M Leary, K Fox

(2018), Vol. 154, pp. 326-339, Materials and design, Amsterdam, The Netherlands, C1

journal

Dynamic and responsive growth factor delivery from electrospun and hydrogel tissue engineering materials

Kiara Bruggeman, Richard Williams, David Nisbet

(2018), Vol. 7, pp. 1-14, Advanced healthcare materials, London, Eng., C1

journal

Using minimalist self-assembling peptides as hierarchical scaffolds to stabilise growth factors and promote stem cell integration in the injured brain

A Rodriguez, K Bruggeman, Y Wang, T Wang, R Williams, C Parish, D Nisbet

(2018), Vol. 12, pp. e1571-e1579, Journal of tissue engineering and regenerative medicine, London, Eng., C1

journal

Hydrogel-immobilized supercharged proteins

E Campbell, J Grant, Y Wang, M Sandhu, R Williams, D Nisbet, A Perriman, D Lupton, C Jackson

(2018), Vol. 2, pp. 1-11, Advanced biosystems, Chichester, Eng., C1

journal

Shear containment of BDNF within molecular hydrogels promotes human stem cell engraftment and postinfarction remodeling in stroke

D Nisbet, T Wang, K Bruggeman, J Niclis, F Somaa, V Penna, C Hunt, Y Wang, J Kauhausen, R Williams, L Thompson, C Parish

(2018), Vol. 2, pp. 1-13, Advanced biosystems, Chichester, Eng., C1

journal
2017

Facile control over the supramolecular ordering of self-assembled peptide scaffolds by simultaneous assembly with a polysacharride

R Li, M Boyd-Moss, B Long, A Martel, A Parnell, A Dennison, C Barrow, D Nisbet, R Williams

(2017), Vol. 7, pp. 1-8, Scientific reports, London, Eng., C1

journal

Bioprinting and biofabrication with peptide and protein biomaterials

Mitchell Boyd-Moss, Kate Fox, Milan Brandt, David Nisbet, Richard Williams

(2017), Vol. 1030, pp. 95-129, Advances in experimental medicine and biology, United States, C1

journal

Reducing astrocytic scarring after traumatic brain injury with a multifaceted anti-inflammatory hydrogel system

F Maclean, Y Wang, R Walker, M Horne, R Williams, D Nisbet

(2017), Vol. 3, pp. 2542-2549, ACS biomaterials science and engineering, Washington, D.C., C1

journal

Temporally controlled growth factor delivery from a self-assembling peptide hydrogel and electrospun nanofibre composite scaffold

Kiara Bruggeman, Yi Wang, Francesca Maclean, Clare Parish, Richard Williams, David Nisbet

(2017), Vol. 9, pp. 13661-13669, Nanoscale, Cambridge, Eng., C1

journal

Peptide-based scaffolds support human cortical progenitor graft integration to reduce atrophy and promote functional repair in a model of stroke

Fahad Somaa, Ting-Yi Wang, Jonathan Niclis, Kiara Bruggeman, Jessica Kauhausen, Haoyao Guo, Stuart McDougall, Richard Williams, David Nisbet, Lachlan Thompson, Clare Parish

(2017), Vol. 20, pp. 1964-1977, Cell reports, Amsterdam, The Netherlands, C1

journal
2016

Coassembled nanostructured bioscaffold reduces the expression of proinflammatory cytokines to induce apoptosis in epithelial cancer cells

R Li, S Pavuluri, K Bruggeman, B Long, A Parnell, A Martel, S Parnell, F Pfeffer, A Dennison, K Nicholas, C Barrow, D Nisbet, R Williams

(2016), Vol. 12, pp. 1397-1407, Nanomedicine: nanotechnology, biology and medicine, Amsterdam, The Netherlands, C1

journal

Characterisation of minimalist co-assembled fluorenylmethyloxycarbonyl self-assembling peptide systems for presentation of multiple bioactive peptides

C Horgan, A Rodriguez, R Li, K Bruggeman, N Stupka, J Raynes, L Day, J White, R Williams, D Nisbet

(2016), Vol. 38, pp. 11-22, Acta biomaterialia, Amsterdam, The Netherlands, C1

journal

Tailoring minimalist self-assembling peptides for localized viral vector gene delivery

A Rodriguez, T Wang, K Bruggeman, R Li, R Williams, C Parish, D Nisbet

(2016), Vol. 9, pp. 674-684, Nano research, Berlin, Germany, C1

journal

A commentary on the need for 3D-biologically relevant in vitro environments to investigate astrocytes and their role in central nervous system inflammation

F Maclean, R Williams, M Horne, D Nisbet

(2016), Vol. 41, pp. 589-592, Neurochemical research, New York, N.Y., C1

journal

Temporally controlled release of multiple growth factors from a self-assembling peptide hydrogel

Kiara Bruggeman, Alexandra Rodriguez, Clare Parish, Richard Williams, David Nisbet

(2016), Vol. 27, pp. 1-7, Nanotechnology, Bristol, Eng., C1

journal

Automated Fourier space region-recognition filtering for off-axis digital holographic microscopy

Xuefei He, Chuong Nguyen, Mrinalini Pratap, Yujie Zheng, Yi Wang, David Nisbet, Richard Williams, Melanie Rug, Alexander Maier, Woei Lee

(2016), Vol. 7, pp. 3111-3123, Biomedical optics express, Washington, D.C., C1

journal

Integrating biomaterials and stem cells for neural regeneration

Francesca Maclean, Alexandra Rodriguez, Clare Parish, Richard Williams, David Nisbet

(2016), Vol. 25, pp. 214-226, Stem cells and development, New Rochelle, N.Y., C1

journal
2015

Tuning the mechanical and morphological properties of self-assembled peptide hydrogels via control over the gelation mechanism through regulation of ionic strength and the rate of pH change

R Li, C Horgan, B Long, A Rodriguez, L Mather, C Barrow, D Nisbet, R Williams

(2015), Vol. 5, pp. 301-307, RSC advances, Cambridge, Eng., C1

journal

Organogelators based on the norbornane scaffold

S Hickey, S Tripcony, R Li, R Williams, F Pfeffer

(2015), Vol. 27, pp. 425-435, Supramolecular chemistry, Oxford, Eng., C1

journal

Self-assembled peptide nanostructures for the fabrication of cell scaffolds

R Li, A Rodriguez, D Nisbet, C Barrow, R Williams

(2015), pp. 33-61, Micro and nanofabrication using self-assembled biological nanostructures, Amsterdam, The Netherlands, B1

chapter
2014

In vitro response to functionalized self-assembled peptide scaffolds for three-dimensional cell culture

V Modepalli, A Rodriguez, R Li, S Pavuluri, K Nicholas, C Barrow, D Nisbet, R Williams

(2014), Vol. 102, pp. 197-205, Biopolymers - Peptide Science Section, C1

journal

In vivo assessment of grafted cortical neural progenitor cells and host response to functionalized self-assembling peptide hydrogels and the implications for tissue repair

A Rodriguez, T Wang, K Bruggeman, C Horgan, R Li, R Williams, C Parish, D Nisbet

(2014), Vol. 2, pp. 7771-7778, Journal of materials chemistry B, Cambridge, Eng., C1

journal
2013

Monitoring the early stage self-assembly of enzyme-assisted peptide hydrogels

R Williams, J Gardiner, A Sorensen, S Marchesan, R Mulder, K McLean, P Hartley

(2013), Vol. 66, pp. 572-578, Australian journal of chemistry, Melbourne, Vic., C1

journal

Tuning the amino acid sequence of minimalist peptides to present biological signals via charge neutralised self assembly

A Rodriguez, C Parish, D Nisbet, R Williams

(2013), Vol. 9, pp. 3915-3919, Soft Matter, C1

journal
2012

One step multifunctional micropatterning of surfaces using asymmetric glow discharge plasma polymerization

D Menzies, T Gengenbach, J Forsythe, N Birbilis, G Johnson, C Charles, G McFarland, R Williams, C Fong, P Leech, K McLean, B Muir

(2012), Vol. 48, pp. 1907-1909, Chemical Communications, C1

journal

Self-assembled peptides: Characterisation and in vivo response

D Nisbet, R Williams

(2012), Vol. 7, pp. 1-14, Biointerphases, C1

journal
2011

The in vivo performance of an enzyme-assisted self-assembled peptide/protein hydrogel

R Williams, T Hall, V Glattauer, J White, P Pasic, A Sorensen, L Waddington, K McLean, P Currie, P Hartley

(2011), Vol. 32, pp. 5304-5310, Biomaterials, C1-1

journal
2010

Biocatalysed peptide hydrogels : an investigation of self-assembly kinetics using NMR spectroscopy

A Sorensen, P Hartley, R Williams

(2010), Vol. 20, pp. 243-243, European cells and materials, Clavadelstr, Davos, C1-1

journal

Exploiting biocatalysis in peptide self-assembly.

R Williams, R Mart, R Ulijn

(2010), Vol. 94, pp. 107-117, Biopolymers, C1-1

journal
2009

Enzyme-assisted self-assembly under thermodynamic control

R Williams, A Smith, R Collins, N Hodson, A Das, R Ulijn

(2009), Vol. 4, pp. 19-24, Nature Nanotechnology, C1-1

journal

Bio-Responsive Hydrogels for Biomedical Applications

T Mcdonald, A Patrick, R Williams, B Cousins, R Ulijn

(2009), pp. 43-59, Biomedical Applications of Electroactive Polymer Actuators, B1-1

chapter
2008

Fmoc-diphenylalanine self assembles to a hydrogel via a novel architecture based on ?-? interlocked ?-sheets

A Smith, R Williams, C Tang, P Coppo, R Collins, M Turner, A Saiani, R Ulijn

(2008), Vol. 20, pp. 37-41, Advanced Materials, C1-1

journal
2006

Enzyme-triggered self-assembly of peptide hydrogels via reversed hydrolysis

S Toledano, R Williams, V Jayawarna, R Ulijn

(2006), Vol. 128, pp. 1070-1071, Journal of the American Chemical Society, C1-1

journal

Funded Projects at Deakin

Australian Competitive Grants

Generating multi-component scaffolding to influence the differentiation of embryonic stem cells

Dr David Nesbit, Dr Clare Parish, Dr Richard Williams

ARC - Discovery Projects

  • 2014: $40,000
  • 2013: $40,000

Biomaterials for the direct reprograming of reactive astrocytes into functional neurons

Dr David Nisbet, Dr Clare Parish, Dr Richard Williams, Prof Alan Harvey, Dr Vincent Daria

NHMRC Project Grant

  • 2019: $33,290

Supervisions

No completed student supervisions to report