Dr Sarah Shigdar

Bifunctional aptamer-doxorubicin conjugate crosses the blood-brain barrier and selectively delivers Its payload to EpCAM-positive tumor cells

J Macdonald, D Denoyer, J Henri, A Jamieson, I Burvenich, N Pouliot, S Shigdar

(2020), Vol. 30, pp. 117-128, Nucleic acid therapeutics, New Rochelle, N.Y., C1

Antibodies, nanobodies, or aptamers-which is best for deciphering the proteomes of non-model species?

P Dhar, R Samarasinghe, S Shigdar

(2020), Vol. 21, pp. 1-14, International journal of molecular sciences, Basel, Switzerland, C1

Radiolabelled aptamers for theranostic treatment of cancer

Umair Khalid, Chris Vi, Justin Henri, Joanna Macdonald, Peter Eu, Giovanni Mandarano, Sarah Shigdar

(2019), Vol. 12, Pharmaceuticals, Basel, Switzerland, C1

Anything you can do, I can do better: can aptamers replace antibodies in clinical diagnostic applications?

michelle Bauer, mia Strom, david Hammond, Sarah Shigdar

(2019), Vol. 24, pp. 1-13, Molecules, Basel, Swtizerland, C1

Tailored mesoporous silica nanoparticles for controlled drug delivery: platform fabrication, targeted delivery, and computational design and analysis

X She, L Chen, Z Yi, C Li, C He, C Feng, T Wang, S Shigdar, W Duan, L Kong

(2018), Vol. 16, pp. 976-989, Mini-reviews in medicinal chemistry, Beijing, China, C1

Aptamers as potential therapeutic agents for ovarian cancer

J Henri, J Macdonald, M Strom, W Duan, S Shigdar

(2018), Vol. 145, pp. 34-44, Biochimie, Amsterdam, The Netherlands, C1

EpCAM immunotherapy versus specific targeted delivery of drugs

Joanna Macdonald, Justin Henri, Kislay Roy, Emma Hays, Michelle Bauer, Rakesh Veedu, Normand Pouliot, Sarah Shigdar

(2018), Vol. 10, pp. 1-13, Cancers, Basel, Switzerland, C1

Mesoporous silica nanorods toward efficient loading and intracellular delivery of siRNA

L Chen, X She, T Wang, S Shigdar, W Duan, L Kong

(2018), Vol. 20, pp. 1-13, Journal of nanoparticle research, Cham, Switzerland, C1

Development of transferrin receptor aptamers as drug delivery vehicles for the treatment of brain metastases

Joanna Macdonald, G Mandarano, Rakesh Veedu, Sarah Shigdar

(2018), Vol. 2, pp. 15-27, Aptamers, Oxford, Eng., C1

Challenges and opportunities for siRNA-based cancer treatment

T Wang, S Shigdar, H Al Shamaileh, M Gantier, W Yin, D Xiang, L Wang, S-F Zhou, Y Hou, P Wang, W Zhang, C Pu, W Duan

(2017), Vol. 387, pp. 77-83, Cancer letters, Shannon, Ireland, C1

Development of a bifunctional aptamer targeting the transferrin receptor and epithelial cell adhesion molecule (EpCAM) for the treatment of brain cancer metastases

J Macdonald, J Henri, L Goodman, D Xiang, W Duan, S Shigdar

(2017), Vol. 8, pp. 777-784, ACS chemical neuroscience, Washington, D.C., C1

Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells

H Al Shamaileh, T Wang, D Xiang, W Yin, P Tran, R Barrero, P-Z Zhang, Y Li, L Kong, K Liu, S-F Zhou, Y Hou, S Shigdar, W Duan

(2017), Vol. 7, pp. 1-9, Scientific reports, London, Eng., C1

Transforming doxorubicin into a cancer stem cell killer via EpCAM aptamer-mediated delivery

D Xiang, S Shigdar, A Bean, M Bruce, W Yang, M Mathesh, T Wang, W Yin, P Tran, H Shamaileh, R Barrero, P Zhang, Y Li, L Kong, K Liu, S Zhou, Y Hou, A He, W Duan

(2017), Vol. 7, pp. 4071-4086, Theranostics, Sydney, N.S.W., C1

Aptamers and glioblastoma: their potential use for imaging and therapeutic applications

E Hays, W Duan, S Shigdar

(2017), Vol. 18, pp. 1-17, International journal of molecular sciences, Basel, Switzerland, C1

Development of cell-specific aptamers: recent advances and insight into the selection procedures

K Rahimizadeh, H AlShamaileh, M Fratini, M Chakravarthy, M Stephen, S Shigdar, R Veedu

(2017), Vol. 22, Molecules, Basel, Switzerland, C1

The Application of aptamers for immunohistochemistry

M Bauer, J Macdonald, J Henri, W Duan, S Shigdar

(2016), Vol. 26, pp. 120-126, Nucleic acid therapeutics, New Rochelle, N.Y., C1

Truncation and mutation of a transferrin receptor aptamer enhance binding affinity

J Macdonald, P Houghton, D Xiang, W Duan, S Shigdar

(2016), Vol. 26, pp. 348-354, Nucleic acid therapeutics, New Rochelle, N.Y., C1

Nucleic acid aptamer-guided cancer therapeutics and diagnostics: the next generation of cancer medicine

D Xiang, S Shigdar, G Qiao, T Wang, A Kouzani, S Zhou, L Kong, Y Li, C Pu, W Duan

(2015), Vol. 5, pp. 23-42, Theranostics, Wyoming, N.S.W., C1

Aptamer-mediated cancer gene therapy.

D Xiang, S Shigdar, G Qiao, S Zhou, Y Li, M Wei, L Qiao, H Shamaileh, Y Zhu, C Zheng, C Pu, W Duan

(2015), Vol. 15, pp. 109-119, Current Gene Therapy, Bussum, Netherlands, C1

Fabrication of high specificity hollow mesoporous silica nanoparticles assisted by Eudragit for targeted drug delivery.

X She, L Chen, L Velleman, C Li, H Zhu, C He, T Wang, S Shigdar, W Duan, L Kong

(2015), Vol. 445, pp. 151-160, Journal of Colloid and Interface Science, United States, C1

The control of epidermal growth factor grafted on mesoporous silica nanoparticles for targeted delivery

X She, L Chen, L Velleman, C Li, C He, J Denman, T Wang, S Shigdar, W Duan, L Kong

(2015), Vol. 3, pp. 6094-6104, Journal of materials chemistry B, Cambridge, Eng., C1

Superior performance of aptamer in tumor penetration over antibody : implication of aptamer-based theranostics in solid tumors

D Xiang, C Zheng, S Zhou, S Qiao, P Tran, C Pu, Y Li, L Kong, A Kouzani, J Lin, K Liu, L Li, S Shigdar, W Duan

(2015), Vol. 5, pp. 1083-1097, Theranostics, Sydney, N.S.W., C1

Overcoming acquired drug resistance in colorectal cancer cells by targeted delivery of 5-FU with EGF grafted hollow mesoporous silica nanoparticles

L Chen, X She, T Wang, L He, S Shigdar, W Duan, L Kong

(2015), Vol. 7, pp. 14080-14092, Nanoscale, Cambridge, Eng., C1

Cancer stem cell targeted therapy: progress amid controversies

T Wang, S Shigdar, M Gantier,, Y Hou,, L Wang,, Y Li,, H Shamaileh,, W Yin, S Zhou,, X Zhao,, W Duan

(2015), Vol. 6, pp. 44191-44206, Oncotarget, Albany, N.Y., C1

EpCAM aptamer-mediated survivin silencing sensitized cancer stem cells to doxorubicin in a breast cancer model

T Wang, M Gantier, D Xiang, A Bean, M Bruce, S Zhou, M Khasraw, A Ward, L Wang, M Wei, H AlShamaileh, L Chen, X She, J Lin, L Kong, S Shigdar, W Duan

(2015), Vol. 5, pp. 1456-1472, Theranostics, Wyoming, N.S.W., C1

Inflammation and cancer stem cells

S Shigdar, Y Li, S Bhattacharya, M O'Connor, C Pu, J Lin, T Wang, D Xiang, L Kong, M Wei, Y Zhu, S Zhou, W Duan

(2014), Vol. 345, pp. 271-278, Cancer Letters, C1

Improved efficacy and reduced toxicity of doxorubicin encapsulated in sulfatide-containing nanoliposome in a glioma model

J Lin, S Shigdar, D Fang, D Xiang, M Wei, A Danks, L Kong, L Li, L Qiao, W Duan

(2014), Vol. 9, pp. 1-13, Plos One, San Francisco, CA, C1

Cancer stem cells: a contentious hypothesis now moving forward

M O'Connor, D Xiang, S Shigdar, J Macdonald, Y Li, T Wang, C Pu, Z Wang, L Qiao, W Duan

(2014), Vol. 344, pp. 180-187, Cancer letters, Shannon, Ireland, C1

CD44 variant 6 is associated with prostate cancer metastasis and chemo-/radioresistance

J Ni, P Cozzi, J Hao, J Beretov, L Chang, W Duan, S Shigdar, W Delprado, P Graham, J Bucci, J Kearsley, Y Li

(2014), Vol. 74, pp. 602-617, Prostate, Hoboken, NJ, C1

Epithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells

L Li, D Xiang, S Shigdar, W Yang, Q Li, J Lin, K Liu, W Duan

(2014), Vol. 9, pp. 1083-1096, International journal of nanomedicine, Macclesfield, England, C1

RNA aptamers targeting cancer stem cell marker CD133

S Shigdar, L Qiao, S Zhou, D Xiang, T Wang, Y Li, L Lim, L Kong, L Li, W Duan

(2013), Vol. 330, pp. 84-95, Cancer Letters, C1

The use of sensitive chemical antibodies for diagnosis: detection of low levels of Epcam in breast cancer

S Shigdar, C Qian, L Lv, C Pu, Y Li, L Li, M Marappan, J Lin, L Wang, W Duan

(2013), Vol. 8, pp. 1-8, PLoS One, San Diego, United States, C1

Epithelial cell adhesion molecule (EpCAM) is associated with prostate cancer metastasis and chemo/radioresistance via the PI3K/Akt/mTOR signaling pathway

J Ni, P Cozzi, J Hao, J Beretov, L Chang, W Duan, S Shigdar, W Delprado, P Graham, J Bucci, J Kearsley, Y Li

(2013), Vol. 45, pp. 2736-2748, International Journal of Biochemistry and Cell Biology, C1

Inhibition of A/Human/Hubei/3/2005 (H3N2) influenza virus infection by silver nanoparticles in vitro and in vivo

D Xiang, D Xiang, Z Yang, Z Yang, W Duan, W Duan, X Li, X Li, J Yin, J Yin, S Shigdar, S Shigdar, M O'Connor, M O'Connor, M Marappan, M Marappan, X Zhao, X Zhao, Y Miao, Y Miao, B Xiang, B Xiang, C Zheng, C Zheng

(2013), Vol. 8, pp. 4103-4114, International Journal of Nanomedicine, Macclesfield, UK, C1

Aptamers as theranostic agents: modifications, serum stability and functionalisation

S Shigdar, J Macdonald, M O'Connor, T Wang, D Xiang, H Al.Shamaileh, L Qiao, M Wei, S Zhou, Y Zhu, L Kong, S Bhattacharya, C Li, W Duan

(2013), Vol. 13, pp. 13624-13637, Sensors, Basel, Switzerland, C1

Cancer stem cell targeting: The next generation of cancer therapy and molecular imaging

S Shigdar, J Lin, Y Li, C Yang, M Wei, Y Zhu, H Liu, W Duan

(2012), Vol. 3, pp. 227-244, Therapeutic Delivery, C1

Enhanced Antitumor Efficacy and Reduced Systemic Toxicity of Sulfatide-Containing Nanoliposomal Doxorubicin in a Xenograft Model of Colorectal Cancer

J Lin, Y Yu, S Shigdar, D Fang, J Du, M Wei, A Danks, K Liu, W Duan

(2012), Vol. 7, PLoS ONE, C1-1

Role of the EpCAM (CD326) in prostate cancer metastasis and progression

J Ni, P Cozzi, W Duan, S Shigdar, P Graham, K John, Y Li

(2012), Vol. 31, pp. 779-791, Cancer and Metastasis Reviews, C1

Groundwater pre-treatment prevents the onset of chronic ulcerative dermatopathy in juvenile Murray cod, Maccullochella peelii peelii (Mitchell)

A Schultz, S Shigdar, P Jones, A Ward, T Toop

(2011), Vol. 312, pp. 19-25, Aquaculture, C1

Elevated levels of triglyceride and triglyceride-rich lipoprotein triglyceride induced by a high-carbohydrate diet is associated with polymorphisms of APOA5-1131T>C and APOC3-482C>T in Chinese healthy young adults

J Lin, D Fang, J Du, S Shigdar, L Xiao, X Zhou, W Duan

(2011), Vol. 58, pp. 150-157, Annals of Nutrition and Metabolism, C1

Clinical applications of aptamers and nucleic acid therapeutics in haematological malignancies

S Shigdar, A Ward, A De, C Yang, M Wei, W Duan

(2011), Vol. 155, pp. 3-13, British Journal of Haematology, C1

RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule

S Shigdar, J Lin, Y Yu, M Pastuovic, M Wei, W Duan

(2011), Vol. 102, pp. 991-998, Cancer Science, C1-1

Aptamer Therapeutics: The 21st Century`s Magic Bullet of Nanomedicine

Sarah Shigdar, Jasmina Luczo, Ming Wei, Richard Bell, Andrew Danks, Ke Liu, Wei Duan

(2010), Vol. 1, pp. 118-124, The Open Conference Proceedings Journal, C1-1

TaqIB polymorphism in the CETP gene modulates the impact of HC/LF diet on the HDL profile in healthy Chinese young adults

J Du, D Fang, J Lin, L Xiao, X Zhou, S Shigdar, W Duan

(2010), Vol. 21, pp. 1114-1119, Journal of nutritional biochemistry, New York, N.Y., C1-1

Cytochemical characterisation of the leucocytes and thrombocytes from Murray cod (Maccullochella peelii peelii, Mitchell)

S Shigdar, A Harford, A Ward

(2009), Vol. 26, pp. 731-736, Fish and Shellfish Immunology, C1

Functional interaction between mutations in the granulocyte colony-stimulating factor receptor in severe congenital neutropenia

A Ward, J Gits, F Majeed, A Aprikyan, R Lewis, L O'Sullivan, M Freedman, S Shigdar, I Touw, D Dale, Y Dror

(2008), Vol. 142, pp. 653-656, British Journal of Haematology, C1

Blood cells of murray cod Maccullochella peelii peelii (Mitchell)

S Shigdar, D Cook, P Jones, A Harford, A Ward

(2007), Vol. 70, pp. 973-980, Journal of Fish Biology, C1

The platelet glycoprotein Ia/IIa gene polymorphism C807T/G873A: a novel risk factor for retinal vein occlusion

P Dodson, J Haynes, J Starczynski, J Farmer, S Shigdar, G Fegan, R Johnson, C Fegan

(2003), Vol. 17, pp. 772-777, Eye, C1-1