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A/Prof. Tamsyn Crowley

STAFF PROFILE

Position

Associate Professor in Medical Bioinformatics

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Qualifications

Doctor of Philosophy, Deakin University, 2007

Contact

Biography

Dr Crowley began her scientific career at RMIT University followed by completing her PhD at Deakin University in 2004. She then moved to CSIRO's AAHL where she spent 12 years working on projects focused on agriculture. During her time at AAHL she had the opportunity to develop her bioinformatic capabilities. In the later part of the CSIRO position she also established links with Deakin through a joint Bioinformatics position. Recently (2016) Dr Crowley has joined the School of Medicine as an academic staff member teaching in the areas of Pharmacology and Therapeutic development. Dr Crowley Is also the founder of Deakin's Bioinformatic Core Research Facility.

Read more on Tamsyn's profile

Research interests

Bioinformatics, biomarkers, microRNA, NGS, Pigeon milk

Teaching interests

Bioinformatics, Pharmacology, Therapeutic development

Units taught

HMM301, HMM304

Knowledge areas

Bioinformatics, pharmacology, therapeutics and cellular biology.

Projects

  1. Biomarkers in poultry welfare
  2. Biomarkers for animal production
  3. Is the pigeon crop the avian mammary gland?
  4. Identifying novel signalling factors in breast milk: do they play a role in food sensitisation?

Publications

Filter by

2024

Finding biomarkers of experience in animals.

Sarah Babington, Alan Tilbrook, Shane Maloney, Jill Fernandes, Tamsyn Crowley, Luoyang Ding, Archa Fox, Song Zhang, Elise Kho, Daniel Cozzolino, Timothy Mahony, Dominique Blache

(2024), Vol. 15, pp. 1-20, Journal of Animal Science and Biotechnology, London, Eng., C1

journal article

Effects of AM/PM Diets on Laying Performance, Egg Quality, and Nutrient Utilisation in Free-Range Laying Hens

Afsana Jahan, Thi Dao, Natalie Morgan, Tamsyn Crowley, Amy Moss

(2024), Vol. 14, APPLIED SCIENCES-BASEL, C1

journal article
2023

Metformin is Protective Against the Development of Mood Disorders

J Lake, C Bortolasci, A Stuart, J Pasco, S Kidnapillai, B Spolding, T Truong, B Panizzutti, Z Liu, O Dean, T Crowley, M Richardson, J Kim, M Berk, L Williams, K Walder

(2023), Vol. 56, pp. 25-31, Pharmacopsychiatry, C1

journal article

Identification of reversible and druggable pathways to improve beta-cell function and survival in Type 2 diabetes

S Sithara, T Crowley, K Walder, K Aston-Mourney

(2023), Vol. 15, pp. 2165368-, Islets, United States, C1

journal article

Use of a gene expression signature to identify trimetazidine for repurposing to treat bipolar depression

C Bortolasci, S Kidnapillai, B Spolding, T Truong, T Connor, C Swinton, B Panizzutti, Z Liu, A Sanigorski, O Dean, T Crowley, M Richardson, K Bozaoglu, K Vlahos, S Cowdery, B Watmuff, S Steyn, D Wolmarans, B Engelbrecht, C Perry, K Drummond, T Pang, S Jamain, L Gray, S McGee, B Harvey, J Kim, M Leboyer, M Berk, K Walder

(2023), Vol. 25, pp. 661-670, Bipolar Disorders, C1

journal article

Interactions of diet and circadian rhythm to achieve precision nutrition of poultry

Amy Moss, Thi Dao, Tamsyn Crowley, Stuart Wilkinson

(2023), Vol. 63, pp. 1926-1932, Animal Production Science, Melbourne, Vic., C1

journal article

Metergoline Shares Properties with Atypical Antipsychotic Drugs Identified by Gene Expression Signature Screen

C Bortolasci, E Jaehne, D Hernández, B Spolding, T Connor, B Panizzutti, O Dean, T Crowley, A Yung, L Gray, J Kim, M van den Buuse, M Berk, K Walder

(2023), Vol. 41, pp. 502-513, Neurotoxicity Research, C1

journal article
2022

Artificial gut and the applications in poultry: A review

Nishchal Sharma, Shu-Biao Wu, Natalie Morgan, Tamsyn Crowley

(2022), Vol. 10, pp. 156-166, Animal Nutrition, Amsterdam, The Netherlands, C1

journal article

Acute exposure to high temperature affects expression of heat shock proteins in altricial avian embryos

L Galletta, M Craven, A Meillère, T Crowley, K Buchanan, M Mariette

(2022), Vol. 110, pp. 1-7, Journal of Thermal Biology, Amsterdam, The Netherlands, C1

journal article

Strategies for promoting sustainable use and conservation of indigenous chicken breeds in Sub-Saharan Africa: Lessons from low-income countries

C Kanyama, A Moss, T Crowley

(2022), Vol. 11, pp. 1-25, F1000Research, London, Eng., C1

journal article
2021

Novel detection of nasty bugs, prevention is better than cure

M Strom, T Crowley, S Shigdar

(2021), Vol. 22, pp. 1-19, International Journal of Molecular Sciences, Switzerland, C1

journal article

Raw material nutrient variability has substantial impact on the potential profitability of chicken meat production

A Moss, P Chrystal, T Crowley, G Pesti

(2021), Vol. 30, Journal of Applied Poultry Research, C1

journal article

Alternatives to formulate laying hen diets beyond the traditional least-cost model

A Moss, G Parkinson, T Crowley, G Pesti

(2021), Vol. 30, Journal of Applied Poultry Research, C1

journal article

Probiotic Bacillus subtilis 29,784 improved weight gain and enhanced gut health status of broilers under necrotic enteritis condition

C Keerqin, L Rhayat, Z Zhang, K Gharib-Naseri, S Kheravii, E Devillard, T Crowley, S Wu

(2021), Vol. 100, Poultry Science, England, C1

journal article

Precision feeding and precision nutrition: a paradigm shift in broiler feed formulation?

A Moss, P Chrystal, D Cadogan, S Wilkinson, T Crowley, M Choct

(2021), Vol. 34, pp. 354-362, Animal bioscience, Suweon, Korea, C1

journal article
2020

The use of a gene expression signature and connectivity map to repurpose drugs for bipolar disorder

S Kidnapillai, C Bortolasci, M Udawela, B Panizzutti, B Spolding, T Connor, A Sanigorski, O Dean, T Crowley, S Jamain, L Gray, E Scarr, M Leboyer, B Dean, M Berk, K Walder

(2020), Vol. 21, pp. 775-783, World Journal of Biological Psychiatry, England, C1

journal article

Drugs used to treat bipolar disorder act via microRNAs to regulate expression of genes involved in neurite outgrowth

S Kidnapillai, B Wade, C Bortolasci, B Panizzutti, B Spolding, T Connor, T Crowley, S Jamain, L Gray, M Leboyer, M Berk, K Walder

(2020), Vol. 34, pp. 370-379, Journal of Psychopharmacology, United States, C1

journal article

Anticipatory Behavior for a Mealworm Reward in Laying Hens Is Reduced by Opioid Receptor Antagonism but Not Standard Feed Intake

P Taylor, A Hamlin, T Crowley

(2020), Vol. 13, Frontiers in Behavioral Neuroscience, Switzerland, C1

journal article

Spatial variation of bacterial and fungal communities of estuarine seagrass leaf microbiomes

Stacey Trevathan-Tackett, Theo Allnutt, Craig Sherman, Mark Richardson, Tamsyn Crowley, Peter Macreadie

(2020), Vol. 84, pp. 59-74, Aquatic microbial ecology, Oldendorf, Germany, C1

journal article
2019

Solving for X: Evidence for sex-specific autism biomarkers across multiple transcriptomic studies

S Lee, T Quinn, J Lai, S Kong, I Hertz-Picciotto, S Glatt, T Crowley, S Venkatesh, T Nguyen

(2019), Vol. 180, pp. 377-389, American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, United States, C1

journal article

Modulation of high fat diet-induced microbiome changes, but not behaviour, by minocycline

K Hasebe, L Rivera, C Smith, T Allnutt, T Crowley, T Nelson, O Dean, S McGee, K Walder, L Gray

(2019), Vol. 82, pp. 309-318, Brain, Behavior, and Immunity, Netherlands, C1

journal article

Drugs used in the treatment of bipolar disorder and their effects on cholesterol biosynthesis - a possible therapeutic mechanism

S Kidnapillai, C Bortolasci, B Panizzutti, B Spolding, T Connor, K Bonifacio, A Sanigorski, O Dean, T Crowley, S Jamain, L Gray, M Leboyer, M Berk, K Walder

(2019), Vol. 20, pp. 766-777, World Journal of Biological Psychiatry, London, Eng., C1

journal article

A field guide for the compositional analysis of any-omics data

T Quinn, I Erb, G Gloor, C Notredame, M Richardson, T Crowley

(2019), Vol. 8, GigaScience, United States, C1

journal article
2018

Understanding sequencing data as compositions: an outlook and review

Thomas Quinn, Ionas Erb, Mark Richardson, Tamsyn Crowley

(2018), Vol. 34, pp. 2870-2878, Bioinformatics, London, Eng., C1

journal article

Benchmarking differential expression analysis tools for RNA-Seq: Normalization-based vs. log-ratio transformation-based methods

T Quinn, T Crowley, M Richardson

(2018), Vol. 19, BMC Bioinformatics, England, C1

journal article
2017

MicroRNAs in a hypertrophic heart: from foetal life to adulthood

S Sadiq, T Crowley, F Charchar, A Sanigorski, P Lewandowski

(2017), pp. 1-18, Biological reviews : Cambridge philosophical society, Chichester, Eng., C1

journal article

Gene expression signature: A powerful approach for drug discovery in diabetes

S Sithara, T Crowley, K Walder, K Aston-Mourney

(2017), Vol. 232, pp. R131-R139, Journal of Endocrinology, England, C1

journal article

Mapping genotype-phenotype associations of nsSNPs in coiled-coil oligomerization domains of the human proteome

K Mohanasundaram, M Grover, T Crowley, A Goscinski, M Wouters

(2017), Vol. 38, pp. 1378-1393, Human Mutation, United States, C1

journal article

Microbiota of little penguins and short-tailed shearwaters during development

M Dewar, J Arnould, T Allnutt, T Crowley, L Krause, J Reynolds, P Dann, S Smith

(2017), Vol. 12, PLoS ONE, United States, C1

journal article

Leptin receptor signaling via Janus kinase 2/Signal transducer and activator of transcription 3 impacts on ovarian cancer cell phenotypes

J Kumar, H Fang, D McCulloch, T Crowley, A Ward

(2017), Vol. 8, pp. 93530-93540, Oncotarget, Albany, N.Y., C1

journal article

Propr: An R-package for Identifying Proportionally Abundant Features Using Compositional Data Analysis

T Quinn, M Richardson, D Lovell, T Crowley

(2017), Vol. 7, Scientific Reports, England, C1

journal article

Impact of maternal high fat diet on hypothalamic transcriptome in neonatal sprague dawley rats

S Barrand, T Crowley, R Wood-Bradley, K De Jong, J Armitage

(2017), Vol. 12, PLoS ONE, United States, C1

journal article
2016

Selection on mitochondrial variants occurs between and within individuals in an expanding invasion

L Rollins, A Woolnough, B Fanson, M Cummins, T Crowley, A Wilton, R Sinclair, A Butler, W Sherwin

(2016), Vol. 33, pp. 995-1007, Molecular Biology and Evolution, United States, C1

journal article

Clinico-pathological association of delineated miRNAs in uveal melanoma with monosomy 3/disomy 3 chromosomal aberrations

N Venkatesan, J Kanwar, P Deepa, V Khetan, T Crowley, R Raguraman, G Sugneswari, P Rishi, V Natarajan, J Biswas, S Krishnakumar

(2016), Vol. 11, PLoS ONE, United States, C1

journal article

Isolation and detection of microRNA from the egg of chickens

B Wade, M Cummins, A Keyburn, T Crowley

(2016), Vol. 9, pp. 1-6, BMC research notes, London, Eng., C1

journal article
2015

Potential role of glutathione in evolution of thiol-based redox signaling sites in proteins.

K Mohanasundaram, N Haworth, M Grover, T Crowley, A Goscinski, M Wouters

(2015), Vol. 6, pp. 1-15, Frontiers in pharmacology, Lausanne, Switzerland, C1

journal article

Novel therapeutics for cononary artery disease from genome-wide association study data

M Grover, S Ballouz, K Mohanasundaram, R George, A Goscinski, T Crowely, C Sherman, M Wouters

(2015), Vol. 8, pp. 1-11, BMC medical genomics, London, Eng., C1

journal article

Comparative analysis of microRNA expression in mouse and human brown adipose tissue

I Guller, S McNaughton, T Crowley, V Gilsanz, S Kajimura, M Watt, A Russell

(2015), Vol. 16, pp. 1-11, BMC genomics, London, Eng., C1

journal article
2014

Identification of novel therapeutics for complex diseases from genome-wide association data

M Grover, S Ballouz, K Mohanasundaram, R George, C H Sherman, T Crowley, M Wouters

(2014), Vol. 7, BMC Medical Genomics, Seoul, SOUTH KOREA, C1

journal article

Identification of MicroRNAs linked to regulators of muscle protein synthesis and regeneration in young and old skeletal muscle

E Zacharewicz, P Della Gatta, J Reynolds, A Garnham, T Crowley, A Russell, S Lamon

(2014), Vol. 9, pp. 1-25, PLoS One, San Francisco, Calif., C1

journal article
2013

Transcriptome analysis of pigeon milk production - role of cornification and triglyceride synthesis genes

M Gillespie, T Crowley, V Haring, S Wilson, J Harper, J Payne, D Green, P Monaghan, J Donald, K Nicholas, R Moore

(2013), Vol. 14, pp. 1-12, BMC genomics, London, England, C1

journal article

Identification of chicken intestinal microbiota correlated with the efficiency of energy extraction from feed

D Stanley, M Geier, S Denman, V Haring, T Crowley, R Hughes, R Moore

(2013), Vol. 164, pp. 85-92, Veterinary microbiology, Amsterdam, The Netherlands, C1

journal article

Identification of differential duodenal gene expression levels and microbiota abundance correlated with differences in energy utilisation in chickens

B Konsak, D Stanley, V Haring, M Geier, R Hughes, G Howarth, T Crowley, R Moore

(2013), Vol. 53, pp. 1269-1275, Animal production science, Clayton, Vic., C1-1

journal article
2012

The tammar wallaby : a model system to examine domain-specific delivery of milk protein bioactives

K Nicholas, J Sharp, A Watt, S Wanyonyi, T Crowley, M Gillespie, C Lefevre

(2012), Vol. 23, pp. 547-556, Seminars in cell and developmental biology, London, England, C1

journal article

Role of position 627 of PB2 and the multibasic cleavage site of the hemagglutinin in the virulence of H5N1 avian influenza virus in chickens and ducks

K Schat, J Bingham, J Butler, L Chen, S Lowther, T Crowley, R Moore, R Donis, J Lowenthal

(2012), Vol. 7, pp. 1-11, PLoS One, San Francisco, Calif, C1

journal article

Intestinal microbiota associated with differential feed conversion efficiency in chickens

D Stanley, S Denman, R Hughes, M Geier, T Crowley, H Chen, V Haring, R Moore

(2012), Vol. 96, pp. 1361-1369, Applied microbiology and biotechnology, Heidelberg, Germany, C1

journal article

Functional similarities between pigeon 'milk' and mammalian milk : induction of immune gene expression and modification of the microbiota

M Gillespie, D Stanley, H Chen, J Donald, K Nicholas, R Moore, T Crowley

(2012), Vol. 7, pp. 1-10, PLoS one, San Francisco, Calif., C1

journal article
2011

Histological and global gene expression analysis of the 'lactating' pigeon crop

M Gillespie, V Haring, K McColl, P Monaghan, J Donald, K Nicholas, R Moore, T Crowley

(2011), Vol. 12, pp. 1-9, BMC genomics, London England, C1

journal article

Chicken anemia virus : an understanding of the in-vitro host response over time

T Crowley, V Haring, R Moore

(2011), Vol. 24, pp. 3-9, Viral immunology, New Rochelle, N. Y., C1-1

journal article
2003

Isolating conifer DNA: a superior polysaccharide elimination method

T Crowley, M Muralitharan, T Stevenson

(2003), Vol. 21, pp. 1-4, Plant molecular biology reporter, Amsterdam, The Netherlands, C1

journal article
2002

Marker-assisted selection for cyclaneusma minus in pinus radiata

T Crowley, M Muralitharan, T Stevenson, J Simpson

(2002), pp. 372-375, Plant breeding for the 11th millenium: proceedings of the 12th Australasian Plant Breeding Conference, Perth, Western Australia, E1

conference

Funded Projects at Deakin

Australian Competitive Grants

A novel way to suppress growth of Campylobacter in chickens prior to processing

A/Prof Tamsyn Crowley

RIRDC Grant - Research - Rural Industries Research and Development Corporation

  • 2023: $32,273
  • 2022: $10,000
  • 2020: $10,000
  • 2019: $160,000
  • 2018: $166,952
  • 2017: $54,368
  • 2016: $80,000

Other Public Sector Funding

Mani Grover CSIRO top-up Scholarship - Using the Gentrepid, human candidate gene discovery platform to prioritize candidate genes for human inherited disorders

A/Prof Tamsyn Crowley, Mr Mani Grover

CSIRO Scholarship - Commonwealth Scientific and Industrial Research Organisation

  • 2015: $1,750
  • 2014: $7,000
  • 2013: $7,000

Industry and Other Funding

Saving our antibiotics: an innovative way of restoring bacterial sensitivity to antimicrobials

Dr Ben Wade, A/Prof Tamsyn Crowley, A/Prof Sarah Shigdar, Dr Anthony Keyburn

CASS Grant - Research - The CASS Foundation Limited

  • 2018: $41,000

Eggs: protein that's good for the planet and your body

A/Prof Tamsyn Crowley, Dr Meagan Craven

Australian Eggs Limited

  • 2022: $28,389
  • 2021: $9,463

Novel approach to isolating antigen targets and developing an mRNA vaccine against Salmonella enterica.

Ms Kat Matthews, A/Prof Tamsyn Crowley

The University of New England trading as Poultry Hub Australia

  • 2023: $26,820

Other Funding Sources

A new test for the measure of poultry welfare

A/Prof Tamsyn Crowley, Mrs Michelle Cummins

Poultry CRC

  • 2016: $78,224
  • 2015: $26,074
  • 2014: $5,000
  • 2013: $232,040

miRNAs, a novel target for improving broiler chicken health and production

A/Prof Tamsyn Crowley

Poultry CRC

  • 2017: $18,635
  • 2016: $18,634
  • 2015: $37,268

Supervisions

Principal Supervisor
2020

Thomas Quinn

Thesis entitled: Understanding Sequencing Data as Compositions

Doctor of Philosophy (Medicine), School of Medicine

2016

Mani Grover

Thesis entitled: Novel therapeutics for complex diseases from genome-wide association data

Doctor of Philosophy (Medicine), School of Medicine

Kaavya Mohanasundaram

Thesis entitled: Mapping the genotype-phenotype relationship in complex disease

Doctor of Philosophy (Medicine), School of Medicine

Associate Supervisor
2019

Smithamol Sithara

Thesis entitled: A beta-cell specific global approach for drug identification in Type 2 Diabetes

Doctor of Philosophy (Medicine), School of Medicine

2018

Shahzad Sadiq

Thesis entitled: Evaluating the Role of Novel microRNAs in Cardiac Hypertrophy

Doctor of Philosophy (Medicine), School of Medicine

2015

Sugeetha Ramakrishnan

Thesis entitled: The relationship between milk, mammary adipocytes and ECM in regulating murine mammary gland involution

Doctor of Philosophy (Medicine), School of Medicine

Vengama Naidu Modepalli

Thesis entitled: The Marsupial: A unique model for understanding the regulation of lung development

Doctor of Philosophy (Medicine), School of Medicine