Profile image of Wei Duan

Prof Wei Duan

STAFF PROFILE

Position

Alfred Deakin Professor

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Contact

wei.duan@deakin.edu.au
+61 3 522 71149

Research interests

Professor Duan's research focuses on developing nucleic acid aptamer technology platforms for cancer biotechnology, focusing on cancer stem cell-targeted drug, siRNA and miRNA delivery using nanoparticles as well as aptamer-based molecular imaging for early detection of cancer and accurate staging. He heads a cross-disciplinary and translational research team consisting of cancer biologists, oncologists, molecular and cell biologists, material scientists, organic chemists, drug developers, pharmaceutical scientists and mechanical and electronic engineers across several faculties, research centres and teaching hospitals in Deakin. He is also involved in developing novel aptamer-based and microfluidic lab-on-a-chip devices for the application in biodefense, forensic medicine and rapid diagnostics at the point of care. He has published over 160 peer-reviewed original research papers and review articles in international refereed journals, with an h-index of 30 (average citation per article of 25).  Professor Duan has filed 5 international patents on cancer stem related aptamers.  He serves as the Editor-in-Chief for the journal “Drug Design, Development and Therapy” (https://www.dovepress.com/drug-design-development-and-therapy-journal).


Professors Duan has been frequently invited to address international conferences on biomedical research, drug development and molecular medicine.

6. Wei Duan, “Aptamer therapeutics: the 21st century’s magic bullet of nanomedicine”, Second International Conference on Drug Discovery and Therapy'. Feb 1-4, 2010. Dubai, United Arab Emirates.

8. Wei Duan,  RNA Aptamer: The Next Generation of Cancer Stem Cell-targeted Molecular Imaging,  BIT’s 9th Annual Congress of International Drug Discovery Science and Technology, Nov 3-6, 2011, Shenzhen, China;

10. Wei Duan, RNA aptamer-guided nanodrug delivery for the 21st century cancer medicine, 6th Annual Meeting of the Australian chapter of the Controlled Release Society, Melbourne, Nov 26-27, 2012.

11. Wei Duan, “Aptamer-guided nano drug delivery systems for cancer therapy”, Nano- and Microparticle-based drug and vaccine delivery, The 6th Joint Australia-New Zealand chapters of the Controlled Release Society, Brisbane, July 4-5, 2013.

12. W. Duan, “The use of RNA aptamers for diagnosis: detecting low levels of EpCAM in paraffin embedded tissues“, Aptamer in Medicine and Perspectives, Oct 4-5, 2013, Naples, Italy.

13. D.Xiang. S. Shigdar, W. Duan, “Targeting cancer stem cells in vivo using RNA aptamers“, 16th International Symposium on Molecular Medicine/The 18th World Congress on Advances in Oncology, 10-12, October, 2013, Hotel Creta Maris Resort, Greece.

15. T Wang, S Shigdar, Wei Duan, “An aptamer-based siRNA in vivo delivery system targeting cancer stem cells, 5th FIP Pharmaceutical Sciences World Congress, Melbourne, Australia, April 13-16, 2014.

16. Shigdar S, Xiang D, Duan W. Aptamers as effective cancer stem cell targeting modalities. Aptamers- 2014, 24-25th March 2014, Oxford, UK. Aug 25-27, 2015.

17. Wei Duan, “Cancer stem cells targeted delivery of siRNA in vivo: translating Nobel Prize-winning technology to clinic”, 8th Dubai International Conference for Medical Sciences, Ded15-17, 2014, Dubai, United Arab Emirates. 

18. Wei Duan, “Cancer stem cell targeted delivery of siRNA to overcome induced chemoresistance”, European Pharma Congress, Aug 25-27, 2015, Valencia, Spain.

19. Wei Duan, “RNA aptamer-guided in vivo RNAi to overcome chemoresistance”, Health forum of the Silk Road-Int Summit Forum of Research and Development on Traditional Chinese Medicine and Ethnic Medicine, Oct 17-18, 2015, Kunlun Hotel, Urumuqi, Xingjiang, P.R. China.

Knowledge areas

aptamer, chemical antibody, molecular cell bioogy, cancer stem cell, targeted drug delivery, nanomedicine, nanotechnology, novel cancer treatment and diagnostics

Conferences

Invited addresses: 1. Wei Duan, A Novel Paradigm in Mammalian Cell Signaling, Signal TransductionTargets for effective therapeutics, Cambridge Healthtech Institute, Seaport Hotel, Boston, MA, USA, November 8-9, 2004. [My talk was reviewed in Rounding up the usual suspects: protein kinases as the therapeutic targets, S.B. Shears, Drug Discovery Today.10(4):240-242, 2005.] 2. Wei Duan, Signaling via a novel integral plasma membrane pool of protein kinase C, The Hunter Meeting of Cell Biology, Sydney, Australia, 6-8 April, 2005. 3. Wei Duan, Herbal Medicine In AustraliaTransforming Ancient Remedy With Nanotechnology, 59th Indian Pharmaceutical Congress, Varanasi-221 005, Uttar Pradesh, India, 20-23 December, 2007. 4. Wei Duan, Development of Molecular Medicine that Specifically Targets Protein Kinase C in Heart Failure, 10th South China International Congress of Cardiology, Dongfang Hotel, Guangzhou, China, 10-13, April, 2008. 5. Wei Duan, Targeted drug delivery using RNA aptamer and nanoparticlesthe miracle of nanomedicine for the 21st century. VII Thailand Research Fund (TRF) Annual Congress. October 16-18, 2008, Holiday Inn Resort Regent Beach, Cha-Am, Thailand. 6. Wei Duan, Aptamer therapeutics: the 21st centurys magic bullet of nanomedicine, Second International Conference on Drug Discovery and Therapy'. February 1-4, 2010. Dubai, United Arab Emirates. 7. Wei Duan, Nucleic acid aptamer: the pearl in the crown of nanomedicine for molecular imaging of cancer, The 4th International Symposium on Bioanalysis, Biomedical Engineering and Nanotechnology (ISBBN 2010), Hunan University in Changsha, Hunan, China (June 3-6, 2010). 8. Wei Duan, RNA Aptamer: The Next Generation of Cancer Stem Cell-targeted Molecular Imaging, BITs 9th Annual Congress of International Drug Discovery Science and Technology --- Re-think Drug Innovations in Green-Eco Era (Session 7-1-2: Nucleic Acid Therapeutics), November 3-6, 2011, Shenzhen, China.

Media appearances

Being an Australian leader in developing aptamers against cancer stem cells,  Professor Duan is well recognised for his innovative and translational medical research.  For example, his work of developing RNA aptamer for cancer diagnosis and treatment was cited by Senator Kim Carr (Minister for Innovation), in his press release on 7 January 2011 as a fine example of the world-class research carried out by Australian leading researchers funded by the Department of Innovation, Industry, Science and Research, Australian Government.
(http://www.industry.gov.au/science/internationalcollaboration/Documents/Cancer_Diagnostics_Case_Study.pdf)

In addition, Professor Duan’s work has enjoined wide coverage by both domestic and international media (for a TV interview: http://www.youtube.com/watch?feature=player_embedded&v=cn_up61UnQY#at=244).

Newspaper coverage of Professor Duan's research:
1) The Australian newspaper, March 19, 2011, Article by Reporter Alexander Gambotto-Burke.
2) The Age newspaper, Melbourne: July 5, 2010,  Article by Reporter Danny Rose. 

3) Australian Broadcast Corporation, National Australia Radio, March 11, 2011, Interview with Desley Blanch.
4)  Australian Broadcast Corporation, Melbourne Radio, February 17 (17:35), Prime time Interview with Lindy Burns.
5)  Victoria TV Channel 31: Special features at 18:30, 9 March 2011, Length: 7 min 42 sec.
6)  Geelong Advertiser: July 6, 2010, Article by Reporter Joel Cresswell.
7)  Geelong Independent: February 25, 2011, Article by Erin Pearson.

Publications

Filter by

2024

Imaging mRNA in vitro and in vivo with nanofirecracker probes via intramolecular hybridization chain reaction

H Xu, Y Zheng, J Xie, W Duan, L Yu, R Lin, C Li, L Jia

(2024), Vol. 248, pp. 1-7, Biosensors and Bioelectronics, Amsterdam, The Netherlands, C1

journal article
2023

Extracellular Vesicle‐Based Nanodrug Delivery

W Yin, C Pham, S Patel, R Chowdhury, T Nguyen, P Tran, Y Zhu, W Duan

(2023), Vol. 2, pp. 667-688, Supramolecular Nanotechnology: Advanced Design of Self-Assembled Functional Materials, London, Eng., B1

book chapter

In situ imaging miRNAs using multifunctional linear DNA nanostructure

H Xu, M Lin, Y Zheng, X Fang, X Huang, Q Huang, J Xu, W Duan, J Wei, L Jia

(2023), Vol. 253, Talanta, Netherlands, C1

journal article

The roles EpCAM plays to enhance the malignancy of gastric cancer

X Zhao, R Zhao, Y Feng, Z Qiu, X Bai, D Zhang, Y Zhou, H Fang, N Liu, L Chen, C Jia, Y Yuan, X Li, W Duan, G Nie, Y Hou

(2023), Journal of Cancer Research and Clinical Oncology, Berlin, Germany, C1

journal article

Genome-wide identification of aberrant alternative splicing and RNA-binding protein regulators in acute myeloid leukaemia which may contribute to immune microenvironment remodelling

Ying Yang, Yu-Mei Zhang, Yan Wang, Kui Liu, Si-Yuan Cui, Ya-Qin Luo, Wei Zheng, Jie Xu, Wei Duan, Jing-Yi Wang

(2023), Vol. 44, pp. 418-425, Carcinogenesis, Oxford, England, C1

journal article

Epidemiological features, genomic characteristics, and origin tracing of the COVID-19 outbreaks in Beijing from January to September 2022

Zhaomin Feng, Da Huo, Shujuan Cui, Bing Lyu, Zhichao Liang, Fu Li, Peng Yang, Quanyi Wang, Daitao Zhang, Yang Pan, Wei Duan

(2023), Vol. 95, pp. 1-11, Journal of Medical Virology, London, Eng., C1-1

journal article

Development a novel drug delivery formulation targeting to esophageal squamous cell carcinoma

Y Feng, J Ge, D Zhang, X Bai, H Fang, Y Zhou, W Che, W Zhang, R Zhao, Z Qiu, X Zhao, L Xiao, H He, S Cheng, W Duan, R Wang, W Chen, G Nie, Y Hou

(2023), Vol. 19, pp. 1-9, Materials Today Advances, Amsterdam, The Netherlands, C1

journal article

Development of Blueberry-Derived Extracellular Nanovesicles for Immunomodulatory Therapy

T Nguyen, C Pham, R Chowdhury, S Patel, S Jaysawal, Y Hou, H Xu, L Jia, A Duan, P Tran, W Duan

(2023), Vol. 15, Pharmaceutics, C1

journal article
2022

Zwitterionic Block Copolymer Prodrug Micelles for pH Responsive Drug Delivery and Hypoxia-Specific Chemotherapy

J Zhao, Y Peng, D Diaz-Dussan, J White, W Duan, L Kong, R Narain, X Hao

(2022), Vol. 19, pp. 1766-1777, Molecular Pharmaceutics, United States, C1

journal article

Change of Cytokines in Chronic Hepatitis B Patients and HBeAg are Positively Correlated with HBV RNA, Based on Real-world Study

Q Zhang, H Huang, A Sun, C Liu, Z Wang, F Shi, W Duan, X Sun, Q Wang, P Sun, C Pu, Y Zhang

(2022), Vol. 10, pp. 390-397, Journal of Clinical and Translational Hepatology, China, C1

journal article

A novel navigated doxorubicin delivery formulation to breast cancer therapy

S Cheng, Z Lu, Y Feng, X Zhao, R Zhao, Z Qiu, C Jia, L Chen, Y Yuan, X Li, Q Gao, J Xu, Z Shu, W Duan, Y Hou, G Nie, L Xiao

(2022), Vol. 14, pp. 1-14, Materials Today Advances, Amsterdam, The Netherlands, C1

journal article

Temperature-Responsive Aldehyde Hydrogels with Injectable, Self-Healing, and Tunable Mechanical Properties

J Zhao, Y Peng, J Wang, D Diaz-Dussan, W Tian, W Duan, L Kong, X Hao, R Narain

(2022), Vol. 23, pp. 2552-2561, Biomacromolecules, Washington, D.C., C1

journal article

Selection and identification of a specific peptide binding to ovarian cancer cells from a phage-displayed peptide library

Q Gao, L Chen, C Jia, Y Yuan, X Li, Z Lu, Y Feng, R Zhao, X Zhao, Y Wang, S Cheng, C Zhang, J Xu, Z Shu, W Duan, G Nie, L Xiao, Y Hou

(2022), Vol. 44, pp. 951-960, Biotechnology Letters, Netherlands, C1

journal article

Inhibitory Effects of Myriocin on Non-Enzymatic Glycation of Bovine Serum Albumin

L He, Y Liu, J Xu, J Li, G Cheng, J Cai, J Dang, M Yu, W Wang, W Duan, K Liu

(2022), Vol. 27, pp. 1-18, Molecules, Basel, Switzerland, C1

journal article

Inhibition of Autophagy Promotes the Elimination of Liver Cancer Stem Cells by CD133 Aptamer-Targeted Delivery of Doxorubicin

W Yin, C Pham, T Wang, H Al Shamaileh, R Chowdhury, S Patel, Y Li, L Kong, Y Hou, Y Zhu, S Chen, H Xu, L Jia, W Duan, D Xiang

(2022), Vol. 12, pp. 1-14, Biomolecules, Basel, Switzerland, C1

journal article

A test-retest resting, and cognitive state EEG dataset during multiple subject-driven states

Yulin Wang, Wei Duan, Debo Dong, Lihong Ding, Xu Lei

(2022), Vol. 9, pp. 1-11, Scientific Data, London, Eng., C1-1

journal article

Biological Activities of Some Natural Compounds and Their Cytotoxicity Studies against Breast and Prostate Cancer Cell Lines and Anti-COVID19 Studies

Xin Liu, Jiangtao Zhao, Guoqiang Qiu, Tahani Alahmadi, Sulaiman Alharbi, Milton Wainwright, Wei Duan

(2022), Vol. 71, pp. 587-597, Journal of oleo science, Tokyo, Japan, C1-1

journal article

Test-retest reproducibility comparison in resting and the mental task states: A sensor and source-level EEG spectral analysis

Lihong Ding, Wei Duan, Yulin Wang, Xu Lei

(2022), Vol. 173, pp. 20-28, International Journal of Psychophysiology, Amsterdam, The Netherlands, C1-1

journal article

Impaired alpha rhythm in bad sleeper during nap: A high-density electroencephalogram study

Xiangyue Zhao, Xinyuan Chen, Wei Duan, Wenrui Zhao, Xu Lei

(2022), Vol. 31, pp. 1-7, Journal of Sleep Research, London, Eng., C1-1

journal article
2021

Neuroprotective Effect of Phthalide Derivative CD21 against Ischemic Brain Injury:Involvement of MSR1 Mediated DAMP peroxiredoxin1 Clearance and TLR4 Signaling Inhibition

X Zou, X Yang, Y Gan, D Liu, C Chen, W Duan, J Du

(2021), Vol. 16, pp. 306-317, Journal of Neuroimmune Pharmacology, United States, C1

journal article

Screening and identification of a specific peptide binding to breast cancer cells from a phage-displayed peptide library

H Jin, X Gao, L Xiao, H He, S Cheng, C Zhang, Y Hou, F Song, X Su, Q Gao, Z Lu, R Yang, X Song, J Yang, W Duan, Y Hou

(2021), Vol. 43, pp. 153-164, Biotechnology Letters, Netherlands, C1

journal article

Dual-Cross-Linked Network Hydrogels with Multiresponsive, Self-Healing, and Shear Strengthening Properties

J Zhao, D Diaz-Dussan, M Wu, Y Peng, J Wang, H Zeng, W Duan, L Kong, X Hao, R Narain

(2021), Vol. 22, pp. 800-810, Biomacromolecules, United States, C1

journal article

An aptamer-based drug delivery agent (CD133-apt-Dox) selectively and effectively kills liver cancer stem-like cells

G Zhou, S Da Won Bae, R Nguyen, X Huo, S Han, Z Zhang, L Hebbard, W Duan, M Eslam, C Liddle, L Yuen, V Lam, L Qiao, J George

(2021), Vol. 501, pp. 124-132, Cancer Letters, Ireland, C1

journal article

Age-related cognitive decline is associated with microbiota-gut-brain axis disorders and neuroinflammation in mice

M Wu, X Yang, L Xue, W Duan, J Du

(2021), Vol. 402, Behavioural Brain Research, Netherlands, C1

journal article

The APEX1/miRNA-27a-5p axis plays key roles in progression, metastasis and targeted chemotherapy of gastric cancer

H He, F Song, Q Gao, Z Lu, Y Yuan, X Li, L Chen, C Jia, R Yang, J Yang, W Duan, Y Hou

(2021), Vol. 599, International Journal of Pharmaceutics, Netherlands, C1

journal article

Tumor cell membrane-based peptide delivery system targeting the tumor microenvironment for cancer immunotherapy and diagnosis

X Meng, J Wang, J Zhou, Q Tian, B Qie, G Zhou, W Duan, Y Zhu

(2021), Vol. 127, pp. 266-275, Acta biomaterialia, Amsterdam, The Netherlands, C1

journal article

Cancer Stem Cell-Targeted Gene Delivery Mediated by Aptamer-Decorated pH-Sensitive Nanoliposomes

P Moitra, S Misra, K Kumar, P Kondaiah, P Tran, W Duan, S Bhattacharya

(2021), Vol. 7, pp. 2508-2519, ACS Biomaterials Science and Engineering, Washington, Eng., C1

journal article

The inhibition of ABCB1/MDR1 or ABCG2/BCRP enables doxorubicin to eliminate liver cancer stem cells

W Yin, D Xiang, T Wang, Y Zhang, C Pham, S Zhou, G Jiang, Y Hou, Y Zhu, Y Han, L Qiao, P Tran, W Duan

(2021), Vol. 11, Scientific Reports, England, C1

journal article

Bovine extracellular vesicles contaminate human extracellular vesicles produced in cell culture conditioned medium when 'exosome-depleted serum' is utilised

C Pham, S Midge, H Barua, Y Zhang, T Ngoc-Gia Nguyen, R Barrero, A Duan, W Yin, G Jiang, Y Hou, S Zhou, Y Wang, X Xie, P Tran, D Xiang, W Duan

(2021), Vol. 708, Archives of Biochemistry and Biophysics, United States, C1

journal article

ITGB1 Enhances the Proliferation, Survival, and Motility in Gastric Cancer Cells

S Cheng, X Li, Y Yuan, C Jia, L Chen, Q Gao, Z Lu, R Yang, G Nie, J Yang, W Duan, L Xiao, Y Hou

(2021), Vol. 27, pp. 1192-1201, Microscopy and Microanalysis, C1

journal article

Lef1 enhances the progression of colonic adenocarcinoma via remodeling the cell motility associated structures

L Xiao, C Zhang, X Li, C Jia, L Chen, Y Yuan, Q Gao, Z Lu, Y Feng, R Zhao, X Zhao, S Cheng, Z Shu, J Xu, W Duan, G Nie, Y Hou

(2021), Vol. 22, International Journal of Molecular Sciences, Switzerland, C1

journal article

Bioinformatic identification of key biomarkers in the brain and blood involved in ischemia preconditioning protection against acute ischemic stroke in mice

Yu-Xin Yang, Mei-Ling Wu, Ou Du, Wei Duan, Jun-Rong Du

(2021), Vol. 14, pp. 1628-+, International Journal of Clinical and Experimental Medicine, Madison, Wis., C1

journal article

Aptamer-mediated doxorubicin delivery reduces HCC burden in 3D organoids model

K Zhou, X Huo, R Nguyen, S Bae, S Han, Z Zhang, W Duan, L Yuen, V Lam, J George, L Qiao

(2021), Vol. 341, pp. 341-350, Journal of Controlled Release, Amsterdam, The Netherlands, C1

journal article

Real-world experience of olaparib treatment in patients with ovarian cancer: A Chinese multicenter study

H Zheng, Y Gao, H Guo, L Li, Q Li, H Cui, A Lin, L Sun, Y Hu, S Kang, W Duan, L Pan, S Wang, Y Yang, Y Li, W Kong, Y Xiang, X Tian, B Ling, C Ha, W Bai

(2021), Vol. 20, pp. 1735-1742, Molecular Cancer Therapeutics, Philadelphia, Pass., C1-1

journal article

Diphenyl pyrimidine exhibits protective effect on Staphylococcus aureus pneumonia in rat model by targeting NLRP3 expression

Wei Duan, Feizhang Qin, Dean Wu, Yunhong Dai

(2021), Vol. 161, pp. 1-6, Microbial Pathogenesis, Amsterdam, The Netherlands, C1-1

journal article

Reproducibility of power spectrum, functional connectivity and network construction in resting-state EEG

Wei Duan, Xinyuan Chen, Ya-Jie Wang, Wenrui Zhao, Hong Yuan, Xu Lei

(2021), Vol. 348, pp. 1-11, Journal of Neuroscience Methods, Amsterdam, The Netherlands, C1-1

journal article
2020

Exosomes and nanoengineering: a match made for precision therapeutics

Phuong Tran, Dongxi Xiang, Thao Tran, Wang Yin, Yumei Zhang, Lingxue Kong, Kuisheng Chen, Miaomiao Sun, Yong Li, Yingchun Hou, Yimin Zhu, Wei Duan

(2020), Vol. 32, pp. 1-8, Advanced materials, Weinheim, Germany, C1

journal article

Development of conjugate-by-conjugate structured nanoparticles for oral delivery of docetaxel

P Ha-Lien Tran, T Wang, C Yang, T Tran, W Duan

(2020), Vol. 107, Materials Science and Engineering C, Netherlands, C1

journal article

Fucoidan-based nanostructures: A focus on its combination with chitosan and the surface functionalization of metallic nanoparticles for drug delivery

P Tran, W Duan, T Tran

(2020), Vol. 575, International Journal of Pharmaceutics, Netherlands, C1

journal article

Current perspectives on delivery systems using extracellular vesicles in neurological disease

P Tran, W Duan, B Lee, T Tran

(2020), Vol. 26, pp. 764-771, Current pharmaceutical design, Sharjah, United Arab Emirates, C1

journal article

CD44 variant 6 is associated with prostate cancer growth and chemo-/radiotherapy response in vivo

J Ni, B Cheung, J Beretov, W Duan, J Bucci, D Malouf, P Graham, Y Li

(2020), Vol. 388, Experimental Cell Research, United States, C1

journal article

Aptamer-guided extracellular vesicle theranostics in oncology

P Tran, D Xiang, T Nguyen, T Tran, Q Chen, W Yin, Y Zhang, L Kong, A Duan, K Chen, M Sun, Y Li, Y Hou, Y Zhu, Y Ma, G Jiang, W Duan

(2020), Vol. 10, pp. 3849-3866, Theranostics, Australia, C1

journal article

CDKL3 promotes osteosarcoma progression by activating Akt/PKB

A He, L Ma, Y Huang, H Zhang, W Duan, Z Li, T Fei, J Yuan, H Wu, L Liu, Y Bai, W Dai, Y Wang, H Li, Y Sun, Y Wang, C Wang, T Yuan, Q Yang, S Tian, M Dong, R Sheng, D Xiang

(2020), Vol. 3, Life Science Alliance, United States, C1

journal article

In silico design and validation of high-affinity RNA aptamers targeting epithelial cellular adhesion molecule dimers

D Bell, J Weber, W Yin, T Huynh, W Duan, R Zhou

(2020), Vol. 117, pp. 8486-8493, Proceedings of the National Academy of Sciences of the United States of America, Washington, D.C., C1

journal article

Roles of N-terminal Annexin A2 phosphorylation sites and miR-206 in colonic adenocarcinoma

L Xiao, H Jin, W Duan, Y Hou

(2020), Vol. 253, Life Sciences, Netherlands, C1

journal article

Emerging technologies for profiling extracellular vesicle heterogeneity

G Huang, G Lin, Y Zhu, W Duan, D Jin

(2020), Vol. 20, pp. 2423-2437, Lab on a Chip, London, Eng., C1

journal article

Ring opening polymerization of α-amino acids: Advances in synthesis, architecture and applications of polypeptides and their hybrids

A Rasines Mazo, S Allison-Logan, F Karimi, N Chan, W Qiu, W Duan, N O'Brien-Simpson, G Qiao

(2020), Vol. 49, pp. 4737-4834, Chemical Society Reviews, England, C1

journal article

Phthalide derivative CD21 alleviates cerebral ischemia-induced neuroinflammation: Involvement of microglial M2 polarization via AMPK activation

Y Gan, D Liu, C Chen, W Duan, Y Yang, J Du

(2020), Vol. 886, European Journal of Pharmacology, Netherlands, C1

journal article

Exosomes and breast cancer drug resistance

X Dong, X Bai, J Ni, H Zhang, W Duan, P Graham, Y Li

(2020), Vol. 11, Cell Death and Disease, England, C1

journal article

Facile Preparation of Macromolecular Prodrugs for Hypoxia-Specific Chemotherapy

J Zhao, D Diaz-Dussan, Z Jiang, Y Peng, J White, W Duan, R Narain, X Hao, L Kong

(2020), Vol. 9, pp. 1687-1692, ACS Macro Letters, United States, C1

journal article

Influenza Vaccination and Non-Pharmaceutical Measure Effectiveness for Preventing Influenza Outbreaks in Schools: A Surveillance-Based Evaluation in Beijing

Ying Sun, Peng Yang, Quanyi Wang, Li Zhang, Wei Duan, Yang Pan, Shuangsheng Wu, Huaqing Wang

(2020), Vol. 8, pp. 1-10, Vaccines, Basel, Switzerland, C1-1

journal article

Impaired Coupling of the Brain's Default Network During Sleep Deprivation: A Resting-State EEG Study

Ya-Jie Wang, Wei Duan, Xu Lei

(2020), Vol. 12, pp. 937-947, Nature and Science of Sleep, Auckland, New Zealand, C1-1

journal article

Mycobacterium tuberculosis PE31 (Rv3477) Attenuates Host Cell Apoptosis and Promotes Recombinant M. smegmatis Intracellular Survival via Up-regulating GTPase Guanylate Binding Protein-1

Md Ali, Gong Zhen, Lambert Nzungize, Andrea Stojkoska, Xiangke Duan, Chunyan Li, Wei Duan, Junqi Xu, Jianping Xie

(2020), Vol. 10, pp. 1-12, Frontiers in Cellular and Infection Microbiology, Lausanne, Switzerland, C1-1

journal article

Mycobacterium tuberculosis Rv0426c promotes recombinant mycobacteria intracellular survival via manipulating host inflammatory cytokines and suppressing cell apoptosis

Cao Ruan, Jiang Li, Jingjing Niu, Ping Li, Yu Huang, Xue Li, Wei Duan, Shuangquan Yan, Junfeng Zhen, Jianping Xie

(2020), Vol. 77, pp. 1-9, Infection, Genetics and Evolution, Amsterdam, The Netherlands, C1-1

journal article
2019

Development of a novel drug targeting delivery system for cervical cancer therapy

Y Hou, L Xiao, N Ma, H He, J Li, S Cheng, Q Yang, Y Hou, F Song, H Jin, X Su, J Dong, R Zuo, X Song, W Duan

(2019), Vol. 30, Nanotechnology, England, C1

journal article

A Detailed Protein-SELEX Protocol Allowing Visual Assessments of Individual Steps for a High Success Rate

T Wang, W Yin, H AlShamaileh, Y Zhang, P Tran, T Nguyen, Y Li, K Chen, M Sun, Y Hou, W Zhang, Q Zhao, C Chen, P Zhang, W Duan

(2019), Vol. 30, pp. 1-16, Human Gene Therapy Methods, United States, C1

journal article

Lentiviral vector-mediated overexpression of Klotho in the brain improves Alzheimer's disease-like pathology and cognitive deficits in mice

C Zeng, T Yang, H Zhou, Y Zhao, X Kuang, W Duan, J Du

(2019), Vol. 78, pp. 18-28, Neurobiology of Aging, United States, C1

journal article

Annexin A2 enhances the progression of colorectal cancer and hepatocarcinoma via cytoskeleton structural rearrangements

H He, L Xiao, S Cheng, Q Yang, J Li, Y Hou, F Song, X Su, H Jin, Z Liu, J Dong, R Zuo, X Song, Y Wang, K Zhang, W Duan, Y Hou

(2019), Vol. 25, pp. 950-960, Microscopy and Microanalysis, United States, C1

journal article

The use of zein in the controlled release of poorly water-soluble drugs

P Tran, W Duan, B Lee, T Tran

(2019), Vol. 566, pp. 557-564, International Journal of Pharmaceutics, Netherlands, C1

journal article

Development of a nanoamorphous exosomal delivery system as an effective biological platform for improved encapsulation of hydrophobic drugs

P Tran, T Wang, W Yin, T Tran, H Barua, Y Zhang, S Midge, T Nguyen, B Lee, W Duan

(2019), Vol. 566, pp. 697-707, International Journal of Pharmaceutics, Netherlands, C1

journal article

Nanogels for skin cancer therapy via transdermal delivery: current designs

P Tran, W Duan, B Lee, T Tran

(2019), Vol. 20, pp. 575-582, Current drug metabolism, Beijing, China, C1

journal article

Modulation of drug crystallization and molecular interactions by additives in solid dispersions for improving drug bioavailability

P Tran, W Duan, B Lee, T Tran

(2019), Vol. 25, pp. 2099-2107, Current Pharmaceutical Design, United Arab Emirates, C1

journal article

Drug stabilization in the gastrointestinal tract and potential applications in the colonic delivery of oral zein-based formulations

P Tran, W Duan, B Lee, T Tran

(2019), Vol. 569, International Journal of Pharmaceutics, Netherlands, C1

journal article

Recent developments of nanoparticle-delivered dosage forms for buccal delivery

P Tran, W Duan, T Tran

(2019), Vol. 571, International Journal of Pharmaceutics, Netherlands, C1

journal article

Aspirin-loaded nanoexosomes as cancer therapeutics

P Tran, T Wang, W Yin, T Tran, T Nguyen, B Lee, W Duan

(2019), Vol. 572, International Journal of Pharmaceutics, Netherlands, C1

journal article

Role of two-component regulatory systems in intracellular survival of Mycobacterium tuberculosis

Xue Li, Xi Lv, Yanping Lin, Junfeng Zhen, Cao Ruan, Wei Duan, Yue Li, Jianping Xie

(2019), Vol. 120, pp. 12197-12207, Journal of Cellular Biochemistry, London, Eng., C1-1

journal article

Mycobacterium tuberculosis Rv1473 is a novel macrolides ABC Efflux Pump regulated by WhiB7

Wei Duan, Xue Li, Yan Ge, Zhaoxiao Yu, Ping Li, Jiang Li, Lianhua Qin, Jianping Xie

(2019), Vol. 14, pp. 47-59, Future Microbiology, London, Eng., C1-1

journal article
2018

Tailored mesoporous silica nanoparticles for controlled drug delivery: Platform fabrication, targeted delivery, and computational design and analysis

X She, L Chen, Z Yi, C Li, C He, C Feng, T Wang, S Shigdar, W Duan, L Kong

(2018), Vol. 18, pp. 976-989, Mini-Reviews in Medicinal Chemistry, Netherlands, C1

journal article

Encapsulation of solid dispersion in solid lipid particles for dissolution enhancement of poorly water-soluble drug

K Tran, T Van Vo, B Lee, W Duan, P Tran, T Tran

(2018), Vol. 15, pp. 576-584, Current Drug Delivery, United Arab Emirates, C1

journal article

Aptamers as potential therapeutic agents for ovarian cancer

J Henri, J Macdonald, M Strom, W Duan, S Shigdar

(2018), Vol. 145, pp. 34-44, Biochimie, Amsterdam, The Netherlands, C1

journal article

Mesoporous silica nanorods toward efficient loading and intracellular delivery of siRNA

L Chen, X She, T Wang, S Shigdar, W Duan, L Kong

(2018), Vol. 20, Journal of Nanoparticle Research, C1

journal article

Switching off the interactions between graphene oxide and doxorubicin using Vitamin C: Combining simplicity and efficiency in drug delivery

Z Liu, J Liu, T Wang, Q Li, P Francis, C Barrow, W Duan, W Yang

(2018), Vol. 6, pp. 1251-1259, Journal of Materials Chemistry B, England, C1

journal article

Aptamers as targeting ligands and therapeutic molecules for overcoming drug resistance in cancers

G Zhou, O Latchoumanin, L Hebbard, W Duan, C Liddle, J George, L Qiao

(2018), Vol. 134, pp. 107-121, Advanced drug delivery reviews, Amsterdam, The Netherlands, C1

journal article

Current designs of polymer blends in solid dispersions for improving drug bioavailability

P Tran, W Duan, B Lee, T Tran

(2018), Vol. 19, pp. 1111-1118, Current Drug Metabolism, Netherlands, C1

journal article

Epithelial cell adhesion molecule (EpCAM) is involved in prostate cancer chemotherapy/radiotherapy response in vivo

J Ni, P Cozzi, J Beretov, W Duan, J Bucci, P Graham, Y Li

(2018), Vol. 18, BMC Cancer, England, C1

journal article

RNA aptamers-guided precision cancer medicine

W Duan, T Wang, S Shigdar, P Tran

(2018), Vol. 63, pp. 529-535, BME6 2016 : 6th International Conference on the Development of Biomedical Engineering in Vietnam, Ho Chi Minh City, Vietnam, E1

conference
2017

Challenges and opportunities for siRNA-based cancer treatment

T Wang, S Shigdar, H Shamaileh, M Gantier, W Yin, D Xiang, L Wang, S Zhou, Y Hou, P Wang, W Zhang, C Pu, W Duan

(2017), Vol. 387, pp. 77-83, Cancer Letters, Ireland, C1

journal article

Sonication-assisted nanoprecipitation in drug delivery

A Vo, T Luu, M Nguyen, T Vo, W Duan, P Tran, T Tran

(2017), Vol. 18, pp. 145-156, Current Drug Metabolism, Netherlands, C1

journal article

Development of a Bifunctional Aptamer Targeting the Transferrin Receptor and Epithelial Cell Adhesion Molecule (EpCAM) for the Treatment of Brain Cancer Metastases

J Macdonald, J Henri, L Goodman, D Xiang, W Duan, S Shigdar

(2017), Vol. 8, pp. 777-784, ACS Chemical Neuroscience, United States, C1

journal article

Strategies of engineering nanoparticles for treating neurodegenerative disorders

K Nguyen, M Pham, T Van Vo, W Duan, P Tran, T Truong-Dinh Tran

(2017), Vol. 18, pp. 786-797, Current Drug Metabolism, Netherlands, C1

journal article

Predictive value of UGT1A1*28 polymorphism in irinotecan-based chemotherapy

X-H Liu, J Lu, W Duan, Z-M Dai, M Wang, S Lin, P-T Yang, T Tian, K Liu, Y-Y Zhu, Y Zheng, Q-W Sheng, Z-J Dai

(2017), Vol. 8, pp. 691-703, Journal of cancer, Wyoming, N.S.W., C1

journal article

Nanotechnology in neuroscience and its perspective as gene carrier

T Khanh, D Wei, P Tran, T Tran

(2017), Vol. 17, pp. 1379-1389, Current Topics in Medicinal Chemistry, United Arab Emirates, C1-1

journal article

Effects of miR-29a and miR-101a expression on myocardial interstitial collagen generation after aerobic exercise in myocardial-infarcted rats

L Xiao, H He, L Ma, M Da, S Cheng, Y Duan, Q Wang, H Wu, X Song, W Duan, Z Tian, Y Hou

(2017), Vol. 48, pp. 27-34, Archives of medical research, Amsterdam, The Netherlands, C1

journal article

New pH-responsive gemini lipid derived co-liposomes for efficacious doxorubicin delivery to drug resistant cancer cells

P Moitra, K Kumar, S Sarkar, P Kondaiah, W Duan, S Bhattacharya

(2017), Vol. 53, pp. 8184-8187, Chemical Communications, England, C1

journal article

Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells

H Alshamaileh, T Wang, D Xiang, W Yin, P Tran, R Barrero, P Zhang, Y Li, L Kong, K Liu, S Zhou, Y Hou, S Shigdar, W Duan

(2017), Vol. 7, Scientific Reports, England, C1

journal article

Nano-sized solid dispersions based on hydrophobic-hydrophilic conjugates for dissolution enhancement of poorly water-soluble drugs

H Dinh, P Tran, W Duan, B Lee, T Tran

(2017), Vol. 533, pp. 93-98, International Journal of Pharmaceutics, Netherlands, C1

journal article

Aptamer-based therapeutic approaches to target cancer stem cells

G Zhou, O Latchoumanin, M Bagdesar, L Hebbard, W Duan, C Liddle, J George, L Qiao

(2017), Vol. 7, pp. 3948-3961, Theranostics, Australia, C1

journal article

Transforming doxorubicin into a cancer stem cell killer via EpCAM aptamer-mediated delivery

D Xiang, S Shigdar, A Bean, M Bruce, W Yang, M Mathesh, T Wang, W Yin, P Tran, H Shamaileh, R Barrero, P Zhang, Y Li, L Kong, K Liu, S Zhou, Y Hou, A He, W Duan

(2017), Vol. 7, pp. 4071-4086, Theranostics, Australia, C1

journal article

Nanoprecipitation for poorly water-soluble drugs

T Nguyen, V Tran, W Duan, P Tran, T Tran

(2017), Vol. 18, pp. 1000-1015, Current Drug Metabolism, Netherlands, C1

journal article

Conjugation strategies for colonic delivery and its application in colorectal cancer therapy

P Tran, W Duan, T Tran

(2017), Vol. 18, pp. 1016-1019, Current drug metabolism, Beijing, China, C1

journal article

Aptamers and glioblastoma: Their potential use for imaging and therapeutic applications

E Hays, W Duan, S Shigdar

(2017), Vol. 18, International Journal of Molecular Sciences, Switzerland, C1

journal article

Influenza vaccination in preventing outbreaks in schools: A long-term ecological overview

Yang Pan, Quanyi Wang, Peng Yang, Li Zhang, Shuangsheng Wu, Yi Zhang, Ying Sun, Wei Duan, Chunna Ma, Man Zhang, Xingxing Zhang, C MacIntyre

(2017), Vol. 35, pp. 7133-7138, Vaccine, Amsterdam, The Netherlands, C1-1

journal article

Mycobacterium tuberculosis PPE44 (Rv2770c) is involved in response to multiple stresses and promotes the macrophage expression of IL-12 p40 and IL-6 via the p38, ERK, and NF-kappa B signaling axis

Zhaoxiao Yu, Chenhui Zhang, Mingliang Zhou, Qiming Li, Hui Li, Wei Duan, Xue Li, Yonghong Feng, Jianping Xie

(2017), Vol. 50, pp. 319-329, International Immunopharmacology, Amsterdam, The Netherlands, C1-1

journal article

Batf3-dependent CD8 alpha(+) Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages

Yalin Li, Xueyan Liu, Wei Duan, Hua Tian, Guangming Zhu, Hao He, Shutong Yao, Shuying Yi, Wengang Song, Hua Tang

(2017), Vol. 18, pp. 188-198, EBioMedicine, Amsterdam, The Netherlands, C1-1

journal article
2016

Application of aptamers in histopathology

S Shigdar, L Lv, L Wang, W Duan

(2016), Vol. 1380, pp. 191-196, Nucleic acid aptamers : selection, characterization and application, New York, N.Y., B1

book chapter

Development of a Sustained Release Solid Dispersion Using Swellable Polymer by Melting Method

T Nguyen, P Tran, T Van Vo, W Duan, T Truong-Dinh Tran

(2016), Vol. 33, pp. 102-109, Pharmaceutical Research, United States, C1

journal article

Development of drug-loaded chitosan-vanillin nanoparticles and its cytotoxicity against HT-29 cells

P-W Li, G Wang, Z-M Yang, W Duan, Z Peng, L-X Kong, Q-H Wang

(2016), Vol. 23, pp. 30-35, Drug delivery, Abingdon, Eng., C1

journal article

The Application of Aptamers for Immunohistochemistry

M Bauer, J Macdonald, J Henri, W Duan, S Shigdar

(2016), Vol. 26, pp. 120-126, Nucleic Acid Therapeutics, United States, C1

journal article

Aptamers: a promising chemical antibody for cancer therapy

G Zhou, G Wilson, L Hebbard, W Duan, C Liddle, J George, L Qiao

(2016), Vol. 7, pp. 13446-13463, Oncotarget, Albany, N.Y., C1

journal article

ANXA2 enhances the progression of hepatocellular carcinoma via remodeling the cell motility associated structures

H Shi, L Xiao, W Duan, H He, L Ma, M Da, Y Duan, Q Wang, H Wu, X Song, Y Hou

(2016), Vol. 85, pp. 26-33, Micron, England, C1

journal article

Perspectives of engineered marine derived polymers for biomedical nanoparticles

K Tran, T Vo, W Duan, P Tran, T Tran

(2016), Vol. 22, pp. 2844-2856, Current Pharmaceutical Design, United Arab Emirates, C1

journal article

An investigation of effects of modification processes on physical properties and mechanism of drug release for sustaining drug release from modified rice

V Ngo, T Luu, T Van Vo, V Tran, W Duan, P Tran, T Tran

(2016), Vol. 67, pp. 1-7, Materials Science and Engineering C, Netherlands, C1

journal article

Targeting epithelial-mesenchymal transition and cancer stem cells for chemoresistant ovarian cancer

J Deng, L Wang, H Chen, J Hao, J Ni, L Chang, W Duan, P Graham, Y Li

(2016), Vol. 7, pp. 55771-55788, Oncotarget, Orchard Park, N.Y., C1

journal article

Investigation of fucoidan-oleic acid conjugate for delivery of curcumin and paclitaxel

U Phan, K Nguyen, T Vo, W Duan, P Tran, T Tran

(2016), Vol. 16, pp. 1281-1287, Anti-Cancer Agents in Medicinal Chemistry, Netherlands, C1

journal article

Truncation and Mutation of a Transferrin Receptor Aptamer Enhances Binding Affinity

J MacDonald, P Houghton, D Xiang, W Duan, S Shigdar

(2016), Vol. 26, pp. 348-354, Nucleic Acid Therapeutics, United States, C1

journal article

Inhibition of Aurora kinases induces apoptosis and autophagy via AURKB/p70S6K/RPL15 axis in human leukemia cells

S He, L Shu, Z Zhou, T Yang, W Duan, X Zhang, Z He, S Zhou

(2016), Vol. 382, pp. 215-230, Cancer Letters, Ireland, C1

journal article

Hydrophilic-hydrophobic polymer blend for modulation of crystalline changes and molecular interactions in solid dispersion

H Van Ngo, P Nguyen, T Van Vo, W Duan, V Tran, P Tran, T Tran

(2016), Vol. 513, pp. 148-152, International Journal of Pharmaceutics, Netherlands, C1

journal article

Proteomics discovery of chemoresistant biomarkers for ovarian cancer therapy

J Deng, L Wang, J Ni, J Beretov, V Wasinger, D Wu, W Duan, P Graham, Y Li

(2016), Vol. 13, pp. 905-915, Expert Review of Proteomics, England, C1

journal article

Proteomic identification of the lactate dehydrogenase A in a radioresistant prostate cancer xenograft mouse model for improving radiotherapy

J Hao, P Graham, L Chang, J Ni, V Wasinger, J Beretov, J Deng, W Duan, J Bucci, D Malouf, D Gillatt, Y Li

(2016), Vol. 7, pp. 74269-74285, Oncotarget, United States, C1

journal article

indium doped and carbon modified p25 nanocomposites with high visible-light sensitivity for the photocatalytic degradation of organic dyes

Z Jin, W Duan, W Duan, B Liu, X Chen, F Yang, J Guo

(2016), Vol. 517, pp. 129-140, Applied Catalysis A: General, Amsterdam, The Netherlands, C1-1

journal article

Overexpression of p53 Improves Blood Glucose Control in an Insulin Resistant Diabetic Mouse Model

Xuemei Zhang, Wei Duan, Wai-Nang Lee, Yuewei Zhang, Fenfen Xiang, Qian Liu, Vay Go, Gary Xiao

(2016), Vol. 45, pp. 1010-1017, Pancreas, Baltimore, Md., C1-1

journal article
2015

Cytokine networks and cancer stem cells

C Liongue, A Ward, W Duan, S Shigdar

(2015), pp. 67-87, Cancer stem cells : emerging concepts and future perspectives in translational oncology, Berlin, Germany, B1

book chapter

A protocol for improving fabrication yield of thin SU-8 microcantilevers for use in an aptasensor

Y Lim, A Kouzani, A Kaynak, X Dai, G Littlefair, W Duan

(2015), Vol. 21, pp. 371-380, Microsystem technologies, Berlin, Germany, C1

journal article

Epigallocatechin-3-gallate induces the apoptosis of hepatocellular carcinoma LM6 cells but not non-cancerous liver cells.

Y Zhang, W Duan, L Owusu, D Wu, Y Xin

(2015), Vol. 35, pp. 117-124, International Journal of Molecular Medicine, Athens, Greece, C1

journal article

Graphene quantum dots induce apoptosis, autophagy, and inflammatory response via p38 mitogen-activated protein kinase and nuclear factor-κB mediated signaling pathways in activated THP-1 macrophages.

Y Qin, Z Zhou, S Pan, Z He, X Zhang, J Qiu, W Duan, T Yang, S Zhou

(2015), Vol. 327, pp. 62-76, Toxicology, Ireland, C1

journal article

Nucleic acid aptamer-guided cancer therapeutics and diagnostics: the next generation of cancer medicine

D Xiang, S Shigdar, G Qiao, T Wang, A Kouzani, S Zhou, L Kong, Y Li, C Pu, W Duan

(2015), Vol. 5, pp. 23-42, Theranostics, Wyoming, N.S.W., C1

journal article

Aptamer-mediated cancer gene therapy.

D Xiang, S Shigdar, G Qiao, S Zhou, Y Li, M Wei, L Qiao, H Shamaileh, Y Zhu, C Zheng, C Pu, W Duan

(2015), Vol. 15, pp. 109-119, Current Gene Therapy, Bussum, Netherlands, C1

journal article

Fabrication of high specificity hollow mesoporous silica nanoparticles assisted by Eudragit for targeted drug delivery.

X She, L Chen, L Velleman, C Li, H Zhu, C He, T Wang, S Shigdar, W Duan, L Kong

(2015), Vol. 445, pp. 151-160, Journal of Colloid and Interface Science, United States, C1

journal article

Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells.

Y Ding, Z Zhou, C Ha, X Zhang, S Pan, Z He, J Edelman, D Wang, Y Yang, X Zhang, W Duan, T Yang, J Qiu, S Zhou

(2015), Vol. 9, pp. 425-464, Drug Design, Development and Therapy, New Zealand, C1

journal article

The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells

J Li, Y Yang, Q Liu, Z Zhou, S Pan, Z He, X Zhang, T Yang, S Pan, W Duan, S He, X Chen, J Qiu, S Zhou

(2015), Vol. 9, pp. 1027-1062, Drug design, development and therapy, Macclesfield, Eng., C1

journal article

Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells

Y Wang, Y Yang, R Zhao, S Pan, H Zhe, Z He, W Duan, X Zhang, T Yang, J Qiu, S Zhou

(2015), Vol. 9, pp. 993-1026, Drug design, development and therapy, Auckland, New Zealand, C1

journal article

Clinical association between pharmacogenomics and adverse drug reactions

Z Zhou, X Chen, K Sneed, Y Yang, X Zhang, Z He, K Chow, T Yang, W Duan, S Zhou

(2015), Vol. 75, pp. 589-631, Drugs, Basel, Switzerland, C1

journal article

Sch9 regulates intracellular protein ubiquitination by controlling stress responses

B Qie, Z Lyu, L Lyu, J Liu, X Gao, Y Liu, W Duan, N Zhang, L Du, K Liu

(2015), Vol. 5, pp. 290-300, Redox biology, Amsterdam, The Netherlands, C1

journal article

Chansu inhibits the expression of cortactin in colon cancer cell lines in vitro and in vivo

C Li, S Hashimi, S Cao, J Qi, D Good, W Duan, M Wei

(2015), Vol. 15, pp. 1-8, BMC complementary and alternative medicine, London, Eng., C1

journal article

Clinical pharmacology of dipeptidyl peptidase 4 inhibitors indicated for the treatment of type 2 diabetes mellitus

X Chen, Z He, Z Zhou, T Yang, X Zhang, Y Yang, W Duan, S Zhou

(2015), Vol. 42, pp. 999-1024, Clinical and experimental pharmacology and physiology, London, Eng., C1

journal article

Cisplatin-induced formation of biocompatible and biodegradable polypeptide-based vesicles for targeted anticancer drug delivery

S Shirbin, K Ladewig, Q Fu, M Klimak, X Zhang, W Duan, G Qiao

(2015), Vol. 16, pp. 2463-2474, Biomacromolecules, Washington, D.C., C1

journal article

The control of epidermal growth factor grafted on mesoporous silica nanoparticles for targeted delivery

X She, L Chen, L Velleman, C Li, C He, J Denman, T Wang, S Shigdar, W Duan, L Kong

(2015), Vol. 3, pp. 6094-6104, Journal of materials chemistry B, Cambridge, Eng., C1

journal article

Superior performance of aptamer in tumor penetration over antibody : implication of aptamer-based theranostics in solid tumors

D Xiang, C Zheng, S Zhou, S Qiao, P Tran, C Pu, Y Li, L Kong, A Kouzani, J Lin, K Liu, L Li, S Shigdar, W Duan

(2015), Vol. 5, pp. 1083-1097, Theranostics, Sydney, N.S.W., C1

journal article

An update on the clinical pharmacology of the dipeptidyl peptidase 4 inhibitor alogliptin used for the treatment of type 2 diabetes mellitus.

X Chen, Z He, Z Zhou, T Yang, X Zhang, Y Yang, W Duan, S Zhou

(2015), Vol. 42, pp. 1225-1238, Clinical and experimental pharmacology and physiology, London, Eng., C1

journal article

Overcoming acquired drug resistance in colorectal cancer cells by targeted delivery of 5-FU with EGF grafted hollow mesoporous silica nanoparticles

L Chen, X She, T Wang, L He, S Shigdar, W Duan, L Kong

(2015), Vol. 7, pp. 14080-14092, Nanoscale, Cambridge, Eng., C1

journal article

Controllable drug uptake and nongenomic response through estrogen-anchored cyclodextrin drug complex

J Yin, S Shumyak, C Burgess, Z Zhou, Z He, X Zhang, S Pan, T Yang, W Duan, J Qiu, S Zhou

(2015), Vol. 10, pp. 4717-4730, International journal of nanomedicine, Auckland, N. Z., C1

journal article

Novel targeting of PEGylated liposomes for codelivery of TGF-β1 siRNA and four antitubercular drugs to human macrophages for the treatment of mycobacterial infection: a quantitative proteomic study

N Niu, J Yin, Y Yang, Z Wang, Z Zhou, Z He, X Chen, X Zhang, W Duan, T Yang, S Zhou

(2015), Vol. 9, pp. 4441-4470, Drug design, development and therapy, Macclesfield, Eng., C1

journal article

Cancer stem cell targeted therapy: progress amid controversies

T Wang, S Shigdar, M Gantier,, Y Hou,, L Wang,, Y Li,, H Shamaileh,, W Yin, S Zhou,, X Zhao,, W Duan

(2015), Vol. 6, pp. 44191-44206, Oncotarget, Albany, N.Y., C1

journal article

EpCAM aptamer-mediated survivin silencing sensitized cancer stem cells to doxorubicin in a breast cancer model

T Wang, M Gantier, D Xiang, A Bean, M Bruce, S Zhou, M Khasraw, A Ward, L Wang, M Wei, H AlShamaileh, L Chen, X She, J Lin, L Kong, S Shigdar, W Duan

(2015), Vol. 5, pp. 1456-1472, Theranostics, Wyoming, N.S.W., C1

journal article
2014

A surface-stress-based microcantilever aptasensor

Y Lim, A Kouzani, W Duan, X Dai, A Kaynak, D Mair

(2014), Vol. 8, pp. 15-24, IEEE transactions on biomedical circuits and systems, Piscataway, NJ, C1

journal article

Improved efficacy and reduced toxicity of doxorubicin encapsulated in sulfatide-containing nanoliposome in a glioma model

J Lin, S Shigdar, D Fang, D Xiang, M Wei, A Danks, L Kong, L Li, L Qiao, W Duan

(2014), Vol. 9, pp. 1-13, Plos One, San Francisco, CA, C1

journal article

Multifunctional nanoparticle-EpCAM aptamer bioconjugates: a paradigm for targeted drug delivery and imaging in cancer therapy

M Das, W Duan, S Sahoo

(2014), pp. 1-11, Nanomedicine : nanotechnology, biology and medicine, Amsterdam, The Netherlands, C1

journal article

Synergistic effects of IAP inhibitor LCL161 and paclitaxel on hepatocellular carcinoma cells.

A Tian, G Wilson, S Lie, G Wu, Z Hu, L Hebbard, W Duan, J George, L Qiao

(2014), Vol. 351, pp. 232-241, Cancer Letters, Ireland, C1

journal article

Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K/Akt/mTOR pathway in human non-small cell lung cancer cells

Y Li, S He, Z He, M Li, Y Yang, J Pang, X Zhang, K Chow, Q Zhou, W Duan, Z Zhou, T Yang, G Huang, A Liu, J Qiu, J Liu, S Zhou

(2014), Vol. 344, pp. 239-259, Cancer Letters, Shannon, County Clare, Ireland, C1

journal article

Cancer stem cells: a contentious hypothesis now moving forward

M O'Connor, D Xiang, S Shigdar, J Macdonald, Y Li, T Wang, C Pu, Z Wang, L Qiao, W Duan

(2014), Vol. 344, pp. 180-187, Cancer letters, Shannon, Ireland, C1

journal article

Cancer stem cells in prostate cancer chemoresistance

J Ni, P Cozzi, J Hao, W Duan, P Graham, J Kearsley, Y Li

(2014), Vol. 14, pp. 225-240, Current cancer drug targets, Bussum, Netherlands, C1

journal article

CD44 variant 6 is associated with prostate cancer metastasis and chemo-/radioresistance

J Ni, P Cozzi, J Hao, J Beretov, L Chang, W Duan, S Shigdar, W Delprado, P Graham, J Bucci, J Kearsley, Y Li

(2014), Vol. 74, pp. 602-617, Prostate, Hoboken, NJ, C1

journal article

Prediction of the likelihood of drug interactions with kinase inhibitors based on in vitro and computational studies

Z-X Wang, J Sun, C Howell, Q-Y Zhou, Z-X He, T Yang, H Chew, W Duan, Z-W Zhou, J Kanwar, S-F Zhou

(2014), Vol. 28, pp. 551-582, Fundamental and clinical pharmacology, Chichester, England, C1

journal article

Smoothened activates breast cancer stem-like cell and promotes tumorigenesis and metastasis of breast cancer

L Wang, W Duan, L Kang, J Mao, X Yu, S Fan, L Li, Y Tao

(2014), Vol. 68, pp. 1099-1104, Biomedicine & pharmacotherapy, Amsterdam, The Netherlands, C1

journal article

Theoretical modeling and experimental validation of surface stress in thrombin aptasensor

Y Lim, A Kouzani, A Kaynak, X Dai, G Littlefair, W Duan

(2014), Vol. 13, pp. 384-391, IEEE Transactions on Nanobioscience, United States, C1

journal article

Epithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells

L Li, D Xiang, S Shigdar, W Yang, Q Li, J Lin, K Liu, W Duan

(2014), Vol. 9, pp. 1083-1096, International journal of nanomedicine, Macclesfield, England, C1

journal article

Exposure to 1800 MHz radiofrequency radiation impairs neurite outgrowth of embryonic neural stem cells

C Chen, Q Ma, C Liu, P Deng, G Zhu, L Zhang, M He, Y Lu, W Duan, L Pei, M Li, Z Yu, Z Zhou

(2014), Vol. 4, pp. 1-10, Scientific reports, London, Eng., C1-1

journal article

∝-mangostin inhibits hypoxia-driven ROS-induced PSC activation and pancreatic cancer cell invasion

J Lei, X Huo, W Duan, Q Xu, R Li, J Ma, X Li, L Han, W Li, H Sun, E Wu, Q Ma

(2014), Vol. 347, pp. 129-138, Cancer letters, Amsterdam, The Netherlands, C1-1

journal article

Design and evaluation of a microcantilever aptasensor

Y Lim, A Kouzani, W Duan, X Dai, A Kaynak, D Mair

(2014), pp. 221-224, ISCAS 2014 : Proceedings of the 2014 IEEE International Symposium on Circuits and Systems, Melbourne, Victoria, E1

conference
2013

Localized surface plasmon resonance: nano-sinusoid arrays

D Mortazavi, A Kouzani, L Matekovits, W Duan

(2013), Vol. 27, pp. 638-648, Journal of electromagnetic waves and applications, London, Eng., C1

journal article

Cloning of the crustacean hyperglycemic hormone and evidence for molt-inhibiting hormone within the central nervous system of the blue crab Portunus pelagicus

M Stewart, P Stewart, M Sroyraya, N Soonklang, S Cummins, P Hanna, W Duan, P Sobhon

(2013), Vol. 164, pp. 276-290, Comparative biochemistry and physiology. Part A : molecular & integrative physiology, New York, N.Y., C1

journal article

RNA aptamers targeting cancer stem cell marker CD133

S Shigdar, L Qiao, S Zhou, D Xiang, T Wang, Y Li, L Lim, L Kong, L Li, W Duan

(2013), Vol. 330, pp. 84-95, Cancer letters, Amsterdam, Netherlands, C1

journal article

The use of sensitive chemical antibodies for diagnosis: detection of low levels of Epcam in breast cancer

S Shigdar, C Qian, L Lv, C Pu, Y Li, L Li, M Marappan, J Lin, L Wang, W Duan

(2013), Vol. 8, pp. 1-8, PLoS One, San Diego, United States, C1

journal article

Epithelial cell adhesion molecule (EpCAM) is associated with prostate cancer metastasis and chemo/radioresistance via the PI3K/Akt/mTOR signaling pathway

J Ni, P Cozzi, J Hao, J Beretov, L Chang, W Duan, S Shigdar, W Delprado, P Graham, J Bucci, J Kearsley, Y Li

(2013), Vol. 45, pp. 2736-2748, International journal of biochemistry and cell biology, Amsterdam, The Netherlands, C1

journal article

Inhibition of A/Human/Hubei/3/2005 (H3N2) influenza virus infection by silver nanoparticles in vitro and in vivo

D Xiang, Z Yang, W Duan, X Li, J Yin, S Shigdar, M O'Connor, M Marappan, X Zhao, Y Miao, B Xiang, C Zheng

(2013), Vol. 8, pp. 4103-4114, International Journal of Nanomedicine, Macclesfield, UK, C1

journal article

Inflammation and cancer stem cells

S Shigdar, Y Li, S Bhattacharya, M O'Connor, C Pu, J Lin, T Wang, D Xiang, L Kong, M Wei, Y Zhu, S Zhou, W Duan

(2013), Vol. 345, pp. 271-278, Cancer letters, Amsterdam, The Netherlands, C1

journal article

Aptamers as theranostic agents: modifications, serum stability and functionalisation

S Shigdar, J Macdonald, M O'Connor, T Wang, D Xiang, H Al.Shamaileh, L Qiao, M Wei, S Zhou, Y Zhu, L Kong, S Bhattacharya, C Li, W Duan

(2013), Vol. 13, pp. 13624-13637, Sensors, Basel, Switzerland, C1

journal article

Selection of DNA aptamers against epithelial cell adhesion molecule for cancer cell imaging and circulating tumor cell capture

Y Song, Z Zhu, Y An, W Zhang, H Zhang, D Liu, C Yu, W Duan, C Yang

(2013), Vol. 85, pp. 4141-4149, Analytical chemistry, Washington DC, C1

journal article

Synthesis and biological evaluation of novel folic acid receptor-targeted, β-cyclodextrin-based drug complexes for cancer treatment

J Yin, S Sharma, S Shumyak, Z Wang, Z Zhou, Y Zhang, P Guo, C Li, J Kanwar, T Yang, S Mohapatra, W Liu, W Duan, J Wang, Q Li, X Zhang, J Tan, L Jia, J Liang, M Wei, X Li, S Zhou

(2013), Vol. 8, pp. 1-20, PLOS one, San Francisco, California, C1

journal article

Peptide-fluorescent bacteria complex as luminescent reagents for cancer diagnosis

B Dong, A Wang, L Yuan, L Chen, K Pu, W Duan, X Yan, Y Zhu

(2013), Vol. 8, PLOS One, San Francisco, California, C1

journal article

Efficacy of using cancer stem cell markers in isolating and characterizing liver cancer stem cells

G Wilson, Z Hu, W Duan, A Tian, X Wang, D McLeod, V Lam, J George, L Qiao

(2013), Vol. 22, pp. 2655-2664, Stem Cells and Development, New Rochelle, NY, C1

journal article

Anti-metastatic and differential effects on protein expression of epigallocatechin-3-gallate in HCCLM6 hepatocellular carcinoma cells

Y Zhang, L Owusu, W Duan, T Jiang, S Zang, A Ahmed, Y Xin

(2013), Vol. 32, pp. 959-964, International journal of molecular medicine, Athens, Greece, C1

journal article

Tumoricidal effects of the JAK inhibitor Ruxolitinib (INC424) on hepatocellular carcinoma in vitro

G Wilson, A Tian, L Hebbard, W Duan, J George, X Li, L Qiao

(2013), Vol. 341, pp. 224-230, Cancer letters, Amsterdam, The Netherlands, C1

journal article

Multifunctional and multitargeted nanoparticles for drug delivery to overcome barriers of drug resistance in human cancers

S Dawar, N Singh, R Kanwar, R Kennedy, R Veedu, S Zhou, S Krishnakumar, S Hazra, S Sasidharan, W Duan, J Kanwar

(2013), Vol. 18, pp. 1292-1300, Drug discovery today, London, England, C1

journal article

The mechanisms of Chansu in inducing efficient apoptosis in colon cancer cells

C Li, S Hashimi, S Cao, A Mellick, W Duan, D Good, M Wei

(2013), Vol. 2013, pp. 1-11, Evidence-based complementary and alternative medicine, New York, N. Y., C1

journal article

Role of surface charge and oxidative stress in cytotoxicity and genotoxicity of graphene oxide towards human lung fibroblast cells

A Wang, K Pu, B Dong, Y Liu, L Zhang, Z Zhang, Duan Wei, Y Zhu

(2013), Vol. 33, pp. 1156-1164, Journal of applied toxicology, Bognor Regis, England, C1-1

journal article
2012

Role of multidrug resistance associated proteins in drug development

S Zhou, J Liu, M Wei, W Duan

(2012), pp. 3-35, Multidrug resistance : a global concern, [San Francisco, Calif.], B1

book chapter

Aptamers and nanomedicine

S Shigdar, A Smith, W Duan

(2012), pp. 275-296, Nanotechnology in health care, Singapore, Singapore, B1-1

book chapter

Developing lspr design guidelines

D Mortazavi, A Kouzani, A Kaynak, W Duan

(2012), Vol. 126, pp. 203-235, Progress in electromagnetics research, Cambridge, Mass., C1

journal article

Cancer stem cell targeting : the next generation of cancer therapy and molecular imaging

S Shigdar, J Lin, Y Li, C Yang, M Wei, Y Zhu, H Liu, W Duan

(2012), Vol. 3, pp. 227-244, Therapeutic delivery, London, England, C1

journal article

Clostridial spores for cancer therapy : targeting solid tumour microenvironment

B Umer, D Good, J Anne, W Duan, M Wei

(2012), Vol. 2012, pp. 1-8, Journal of toxicology, New York, N.Y., C1

journal article

Enhanced antitumor efficacy and reduced systemic toxicity of sulfatide containing nanoliposomal doxorubicin in a xenograft model of colorectal cancer

J Lin, Y Yu, S Shigdar, D Fang, J Rong Du, M Wei, A Danks, K Liu, W Duan

(2012), Vol. 7, pp. 1-10, Plos One, San Francisco, Calif., C1-1

journal article

Apoptosis and microRNA aberrations in cancer

C Li, S Hashimi, D Good, S Cao, W Duan, P Plummer, A Mellick, M Wei

(2012), Vol. 39, pp. 739-746, Clinical and experimental pharmacology and physiology, Australia, C1

journal article

Role of the EpCAM (CD326) in prostate cancer metastasis and progression

J Ni, P Cozzi, W Duan, S Shigdar, P Graham, K John, Y Li

(2012), Vol. 31, pp. 779-791, Cancer metastasis reviews, New York, N. Y., C1

journal article
2011

Cancer gene therapy : developments and future perspectives

D Good, W Duan, J Anne, M Wei

(2011), pp. 299-314, Gene therapy - Developments and Future Perspectives, Rijeka, Croatia, B1

book chapter

Elevated levels of triglyceride and triglyceride-rich lipoprotein triglyceride induced by a high-carbohydrate diet is associated with polymorphisms of AP0A5-1131T>C and AP0C3-482C> in chinese healthy young adults

J Lin, D Fang, J Du, S Shigdar, L Xiao, X Zhou, W Duan

(2011), Vol. 58, pp. 150-157, Annals of nutrition and metabolism, Basel, Switzerland, C1

journal article

Associations of the SREBP-1c gene polymorphism with gender-specific changes in serum lipids induced by a high-carbohydrate diet in healthy Chinese youth

Z Zhang, R Gong, J Du, L Xiao, W Duan, X Zhou, D Fang

(2011), Vol. 36, pp. 226-232, Applied physiology, nutrition and metabolism, Ottawa, Canada, C1

journal article

Clinical applications of aptamers and nucleic acid therapeutics in haematological malignancies

S Shigdar, A Ward, A De, C Yang, M Wei, W Duan

(2011), Vol. 155, pp. 3-13, British journal of haematology, Oxford, U. K., C1

journal article

Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study

Y Liu, S Mo, H Bi, B Hu, C Li, Y Wang, L Huang, M Huang, W Duan, J Liu, M Wei, S Zhou

(2011), Vol. 41, pp. 259-280, Xenobiotica, London, U. K., C1

journal article

Effects of lipoprotein lipase gene variations, a high-carbohydrate low-fat diet, and gender on serum lipid profiles in healthy Chinese Han youth

X Huang, R Gong, J Lin, R Li, L Xiao, W Duan, D Fang

(2011), Vol. 5, pp. 198-204, Bioscience trends, Tokyo, Japan, C1

journal article

RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule

S Shigdar, J Lin, Y Yu, M Pastuovic, M Wei, W Duan

(2011), Vol. 102, pp. 991-998, Cancer Science, Tokyo, Japan, C1-1

journal article

A micromechanical biosensor with interdigitated capacitor readout

Y Lim, A Kouzani, A Kaynak, R Al-Ameri, W Duan

(2011), pp. 42-46, CME 2011 : Proceedings of the 2011 IEEE/ICME International Conference on Complex Medical Engineering, Harbin Heilongjiang, China, E1

conference

Nano-plasmonic biosensors : a review

D Mortazavi, A Kouzani, A Kaynak, W Duan

(2011), pp. 31-36, CME 2011 : Proceedings of the 2011 IEEE/ICME International Conference on Complex Medical Engineering, Harbin Heilongjiang, China, E1

conference
2010

Aptasensors : a review

Y Lim, A Kouzani, W Duan

(2010), Vol. 6, pp. 93-105, Journal of biomedical nanotechnology, Valencia, Calif., C1

journal article

Lab-on-a-chip : a component view

Y Lim, A Kouzani, W Duan

(2010), Vol. 16, pp. 1995-2015, Microsystem technologies : sensors actuators systems integration, Heidelberg, Germany, C1

journal article

Spermatogenesis in the blue swimming crab, Portunus pelagicus, and evidence for histones in mature sperm nuclei

M Stewart, P Stewart, N Soonklang, V Linthong, P Hanna, W Duan, P Sobhon

(2010), Vol. 42, pp. 137-150, Tissue and cell, United Kingdom, C1

journal article

Disposition pathways and pharmacokinetics of herbal medicines in humans

S He, C Li, J Liu, E Chan, W Duan, S Zhou

(2010), Vol. 17, pp. 4072-4113, Current medicinal chemistry, Amsterdam, The Netherlands, C1

journal article

Aptamer therapeutics: the 21st century's magic bullet of nanomedicine

S Shigdar, J Luczo, M Wei, R Bell, A Danks, K Liu, D Wei

(2010), Vol. 1, pp. 118-124, Open conference proceedings journal, Bussum, The Netherlands, C1-1

journal article

TaqIB polymorphism in the CETP gene modulates the impact of HC/LF diet on the HDL profile in healthy Chinese young adults

J Du, D Fang, J Lin, L Xiao, X Zhou, S Shigdar, W Duan

(2010), Vol. 21, pp. 1114-1119, Journal of nutritional biochemistry, New York, N.Y., C1-1

journal article

Effects of design parameters on sensitivity of microcantilever biosensors

Y Lim, A Kouzani, W Duan, A Kaynak

(2010), pp. 177-181, IEEE/ICME 2010 : Proceedings of the 2010 International Conference on Complex Medical Engineering, Gold Coast, Australia, E1

conference

Design and construction of a micropump for drug delivery applications

A Kouzani, M Ivankovic, M Fielding, A Kaynak, C Yang, W Duan, E Hu

(2010), pp. 182-187, IEEE/ICME 2010 : Proceedings of the 2010 International Conference on Complex Medical Engineering, Gold Coast, Australia, E1

conference
2009

Aptasensors design considerations

Y Lim, A Kouzani, W Duan

(2009), pp. 118-127, Computational intelligence and intelligent systems, Berlin, Germany, B1

book chapter

GSK3β modulates PACAP-induced neuritogenesis in PC12 cells by acting downstream of Rap1 in a caveolae-dependent manner

W Zhang, A Smith, J Liu, N Cheung, S Zhou, K Liu, Q Li, W Duan

(2009), Vol. 21, pp. 237-245, Cellular signalling, Amsterdam, The Netherlands, C1

journal article

Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6

S Mo, Y Liu, W Duan, M Wei, J Kanwar, S Zhou

(2009), Vol. 10, pp. 730-753, Current drug metabolism, Hilversum, The Netherlands, C1

journal article

Insights into the Structure, Function, and Regulation of Human Cytochrome P450 1A2

S Zhou, L Yang, M Wei, W Duan, E Chan

(2009), Vol. 10, pp. 713-729, Current drug metabolism, Bussum, Netherlands, C1-1

journal article
2008

Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development

S Zhou, L Wang, Y Di, C Xue, W Duan, C Li, Y Li

(2008), Vol. 15, pp. 1981-2039, Current medicinal chemistry, Schiphol, Netherlands, C1

journal article

The C-terminus of PRK2/PKNγ is required for optimal activation by RhoA in a GTP-dependent manner

W Lim, X Chen, J Liu, B Tan, S Zhou, A Smith, N Lees, L Hou, F Gu, X Yu, Y Du, D Smith, C Verma, K Liu, W Duan

(2008), Vol. 479, pp. 170-178, Archives of biochemistry and biophysics, New York, N.Y., C1

journal article

Clincial pharmacogenetics and potential application in personalized medicine

S Zhou, Y Di, E Chan, Y Du, V Chow, C Xue, X Lai, J Wang, C Li, M Tian, W Duan

(2008), Vol. 9, pp. 738-784, Current drug metabolism, Hilversum, Netherlands, C1

journal article

Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc

D Xu, J Dwyer, L He, W Duan, J Liu

(2008), Vol. 283, pp. 23567-23580, Journal of biological chemistry, Bethesda, Md, C1

journal article

Protein kinase C isozymes as potential therapeutic targets in immune disorders

M Lee, W Duan, S Tan

(2008), Vol. 12, pp. 535-552, Expert opinion on therapeutic targets, London, England, C1

journal article
2007

Emerging host cell targets for hepatitis C therapy

Y He, W Duan, S Tan

(2007), Vol. 12, pp. 209-217, Drug discovery today, Barking, England, C1

journal article

Sulfatide-tenascin interaction mediates binding to the extracellular matrix and endocytic uptake of liposomes in glioma cells

K Shao, Q Hou, M Go, W Duan, N Cheung, S Feng, K Wong, A Yoram, W Zhang, Z Huang, Q Li

(2007), Vol. 64, pp. 506-515, Cellular and molecular life sciences, Basel, Switzerland, C1

journal article

Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge

X Yu, S Lin, Z Zhou, X Chen, J Liang, P Liu, W Duan, B Chowbay, J Wen, S Zhou

(2007), Vol. 8, pp. 1-16, Current drug metabolism, Hilversum, The Netherlands, C1

journal article

Role of P-glycoprotein in limiting the brain penetration of glabridin, an active isoflavan from the root of Glycyrrhiza glabra.

X Yu, Z Zhou, S Lin, X Chen, X Yu, J Liang, W Duan, J Wen, X Li, S Zhou, B Chowbay, E Chan, J Cao, C Li, C Xue

(2007), Vol. 24, pp. 1668-1690, Pharmaceutical research, Delft, The Netherlands, C1

journal article

Role of the ATP-binding cassette drug transporters in the intestinal absorption of tanshinone IIB, one of the major active diterpenoids from the root of Salvia miltiorrhiza

X Yu, Z Zhou, S Lin, X Chen, X Yu, J Liang, W Duan, J Wen, X Li, S Zhou

(2007), Vol. 37, pp. 375-415, Xenobiotica: the fate of foregn compounds in biological systems, Abingdon, England, C1

journal article

Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: Application to cellular metabolism and accumulation studies

Z Hu, X Yang, X Chen, E Chan, W Duan, S Zhou

(2007), Vol. 850, pp. 575-580, Journal of chromatography. B, analytical technologies in the biomedical and life sciences, Amsterdam, Nertherlands, C1

journal article

Histological studies of the ovaries of two tropical portunid crabs, Portunus pelagicus (L.) and Scylla serrata (F.)

M Stewart, N Soonklang, P Stewart, P Hanna, W Chaitip, A Parratt, W Duan, P Sobhon

(2007), Vol. 50, pp. 85-97, Invertebrate reproduction and development, Rehovot, Israel, C1

journal article

Pituitary adenylate cyclase-activating polypeptide induces translocation of its G-protein-coupled receptor into caveolin-enriched membrane microdomains, leading to enhanced cyclic AMP generation and neurite outgrowth in PC12 cells

W Zhang, W Duan, N Cheung, Z Huang, K Shao, Q Li

(2007), Vol. 103, pp. 1157-1167, Journal of neurochemistry, Chichester, England, C1

journal article

Tanshinone IIB, a primary active constituent from Salvia miltiorrhza, exhibits neuro-protective activity in experimentally stroked rats

X Yu, S Lin, Z Zhou, X Chen, J Liang, W Duan, X Yu, J Wen, B Chowbay, C Li, F Sheu, E Chan, S Zhou

(2007), Vol. 417, pp. 261-265, Neuroscience letters, Limerick, Ireland, C1

journal article

Design of new oxazaphosphorine anticancer drugs

J Liang, M Huang, W Duan, X Yu, S Zhou

(2007), Vol. 13, pp. 963-978, Current pharmaceutical design, Hilversum, The Netherlands, C1

journal article

A mechanistic study on altered pharmacokinetics of irinotecan by St. Johns wort

Z Hu, X Yang, X Chen, E Chan, W Duan, M Huang, X Yu, J Wen, S Zhou, J Cao

(2007), Vol. 8, pp. 157-171, Current drug metabolism, Hilversum, The Netherlands, C1

journal article

Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimers disease, across the blood-brain

X Yu, S Lin, X Chen, Z Zhou, J Liang, W Duan, B Chowbay, J Wen, E Chan, J Cao, C Li, S Zhou

(2007), Vol. 8, pp. 365-377, Current drug metabolism, Hilversum, Netherlands, C1

journal article

Role of P-glycoprotein in the intestinal absorption of glabridin, an active flavonoid from the root of Glycyrrhiza glabra

J Cao, X Chen, J Liang, X-Q Yu, A-L Xu, E Chan, W Duan, M Huang, J-Y Wen, X-Y Yu, X-T Li, F-S Sheu, S-F Zhou

(2007), Vol. 35, pp. 539-553, Drug metabolism and disposition, Bethesda, Md., C1-1

journal article
2006

The last 10 amino acid residues beyond the hydrophobic motif are critical for the catalytic competence and function of protein kinase Cá*

S Yeong, Y Zhu, D Smith, C Verma, W Lim, B Tan, Q Li, N Cheung, M Cai, Y Zhu, S Zhou, S Tan, W Duan

(2006), Vol. 281, pp. 30768-30781, Journal of biological chemistry, Bethesda, Md, C1

journal article

The very C-terminus of protein kinase CĹ is critical for the full catalytic competence but its hydrophobic motif is dispensable for the interaction with 3-phosphoinositide-dependent kinase-1

Y Zhu, D Smith, C Verma, W Lim, B Tan, J Armstrong, S Zhou, E Chan, S Tan, Y Zhu, N Cheung, W Duan

(2006), Vol. 18, pp. 807-818, Cellular signalling, Amsterdam, Netherlands, C1-1

journal article

Analysis of cardioprotective effects using purified Saliva miltiorrhiza extract on isolated rat hearts

P Chang, J Mao, S Huang, L Ning, Z Wang, T On, W Duan, Y Zhu

(2006), Vol. 101, pp. 245-249, Journal of Pharmacological Sciences, Japan, C1-1

journal article

Drug-herb interactions: eliminating toxicity with hard drug design.

X Yang, Z Hu, W Duan, Y Zhu, S Zhou

(2006), Vol. 12, pp. 4649-4664, Current pharmaceutical design, Hilversum, The Netherlands, C1-1

journal article

St. Johns wort attenuates irinotecan-induced diarhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosis

Z Hu, X Yang, S Chan, A Xu, W Duan, Y Zhu, F Sheu, U Boelsterli, E Chan, Q Zhang, J Wang, P Rachel Ee, H Koh, M Huang, S Zhou

(2006), Vol. 216, pp. 225-237, Toxicology and applied pharmacology, San Diego Calif., C1-1

journal article

Relationship of glutathione S-transferase genotypes with side-effects of pulsed cyclophsphamide therapy in patients with systemic lupus erythematosus

S Zhong, M Huang, X Yang, L Liang, Y Wang, M Romkes, W Duan, E Chan, S Zhou

(2006), Vol. 62, pp. 457-472, British journal of clinical pharmacology, London, England, C1-1

journal article

Intracellular drug delivery by sulfatide-mediated liposomes to gliomas

K Shao, Q Hou, W Duan, M Go, K Wong, Q Li

(2006), Vol. 115, pp. 150-157, Journal of controlled release, Amsterdam, The Netherlands, C1-1

journal article

Genetic polymorphisms of cytochrome P450 2B6 gene in Han Chinese

S Guan, M Huang, E Chan, X Chen, W Duan, S Zhou

(2006), Vol. 29, pp. 14-21, European journal of pharmaceutical sciences, Amsterdam, The Netherlands, C1-1

journal article

Pharmacokinetics of recombinant human endostatin in rats

X Yang, Z Hu, E Chan, W Duan, S Zhou

(2006), Vol. 7, pp. 565-576, Current drug metabolism, Hilversum, The Netherlands, C1-1

journal article

A mechanistic study on reduced toxicity of irontecan by coadministered thalidomide, a tumor necrosis factor-a inhibitor

X Yang, Z Hu, A Xu, W Duan, Y Zhu, M Huang, F Sheu, Q Zhang, J Bian, E Chan, X Li, J Wang, S Zhou

(2006), Vol. 319, pp. 82-104, Journal of pharmacology and experimental therapeutics, Bethesda, Md., C1-1

journal article

Small interfering RNA-mediated silencing of cytochromeP450 3A4 gene

J Chen, X Yang, M Huang, Z Hu, M He, W Duan, E Chan, F Sheu, X Chen, S Zhou

(2006), Vol. 34, pp. 1650-1657, Drug metabolism and disposition, Bethesda, Md., C1-1

journal article

A mechanistic study of the intestinal absorption of crypotanshinone, the major active constituent of Saliva miltiorrhiza

J Zhang, M Huang, S Guan, H Bi, Y Pan, W Duan, S Chan, X Chen, Y Hong, S Zhou

(2006), Vol. 317, pp. 1285-1294, Journal of pharmacology and experimental therapeutics, Bethesda, Md., C1-1

journal article

Early induction of chalpains in rotenone-mediated neuronal apoptosis

M Chen, Y Yap, M Choy, C Koh, S Seet, W Duan, M Whiteman, N Cheung

(2006), Vol. 397, pp. 69-73, Neuroscience letters, Limerick, Ireland, C1-1

journal article

Nitric oxide protects against mitochondrial permeabilizastion induced by gluthathione depletion: role of S-nitrosylation?

M Whiteman, Y Chua, D Zhang, W Duan, Y Liou, J Armstrong

(2006), Vol. 339, pp. 255-262, Biochemical and biophysical research comminications, San Diego Calif., C1-1

journal article

A study of the effects of flux density and frequency on Pulsed electromagnetic field on Neurite outgrowth in PC12 cells.

Y Zhang, J Ding, W Duan

(2006), Vol. 32, pp. 1-9, Journal of biological physics: an intrnational journal for the formulation and application of physical and mathematical models in the biological sciences, Amsterdam, The Netherlands, C1-1

journal article

Monitoring of immune responses to a herbal immuno-modulator in patients with advanced colorectal cancer.

X Chen, Z Hu, X Yang, M Huang, Y Gao, W Tang, S Chan, X Dai, J Ye, P Ho, W Duan, H Yang, Y Zhu, S Zhou

(2006), Vol. 6, pp. 499-508, International immumopharmacology, Barking, England, C1-1

journal article

Topotecan is a substrate for multidrug resistance associated protein 4

Q Tian, J Zhang, S Chan, T Chin Tan, W Duan, M Huang, Y Zhu, E Chan, Q Yu, Y Nie, P Chi-Liu Ho, Q Li, K Ng, H Yang, H Wei, J Bian, S Zhou

(2006), Vol. 7, pp. 105-118, Current drug metabolism, Hilversum, Netherlands, C1-1

journal article

The very C-terminus of PRK1/PKN is essential for its activation by RhoA and downstream signaling

W Lim, B Tan, Y Zhu, S Zhou, J Armstrong, Q Li, Q Dong, E Chan, D Smith, C Verma, S Tan, W Duan

(2006), Vol. 18, pp. 1473-1481, Cellular signalling, Amsterdam, Netherlands, C1-1

journal article

Use of in vitro critical inhibitory concentration, a novel approach to predict in vivo synergistic bactericidal effect of combined amikacin and piperacillin against pseudomonas aeruginosa in a systemic rat infection model

E Chan, S Zhou, S Sahasranaman, W Duan

(2006), Vol. 23, pp. 729-741, Pharmaceutical research, New York, N.Y., C1-1

journal article

A comparison study of cerebral protection using Ginkgo biloba extract and Losartan on stroked rats

K Loh, L Low, W Wong, S Zhou, S Huang, R Silva, W Duan, W Chou, Y Zhu

(2006), Vol. 398, pp. 28-33, Neuroscienceletters, Limerick, Ireland, C1-1

journal article

U18666A-mediated apoptosis in cultured murine cortical neurons : role of caspases, calpains and kinases

C Koh, R Qi, D Qu, A Melendez, J Manikandan, B Bay, W Duan, N Cheung

(2006), Vol. 18, pp. 1572-1583, Cellular signalling, Amsterdam, Netherlands, C1-1

journal article

Pharmacokinetic mechanisms for reduced toxicity of irinotecan by coadministered Thalidomide

X Yang, Z Hu, S Chan, W Duan, P Ho, U Boelsterli, K Ng, E Chan, J Bian, Y Chen, M Huang, S Zhou

(2006), Vol. 7, pp. 431-454, Current drug metabolism, Hilversum, The Netherlands, C1-1

journal article

Induction of propranolol metabolism by Ginkgo biloba extract EGb 761 in rats

L Zhao, M Huang, J Chen, P Rachel Ee, E Chan, W Duan, Y Guan, Y Hong, X Chen, S Zhou

(2006), Vol. 7, pp. 577-587, Current drug metabolism, Hilversum, The Netherlands, C1-1

journal article

Relationship between genotype and enzyme activity of glutathione S-transferases M1 and P1 in Chinese

S Zhong, S Zhou, X Chen, S Chan, E Chan, K Ng, W Duan, M Huang

(2006), Vol. 28, pp. 77-85, European journal of pharmaceutical sciences, Amsterdam, The Nertherlands, C1-1

journal article
2005

Identification of an integral plasma membrane pool of protein kinase C in mammalian tissues and cells

Y Zhu, W Lim, B Tan, T Teo, W Duan

(2005), Vol. 17, pp. 1125-1136, Cellular signalling, New York, N.Y., C1-1

journal article

The PKCÁ-D294G mutant found in pituitary and thyroid tumors fails to transduce extracellular signals

Y Zhu, Q Dong, B Tan, W Lim, S Zhou, W Duan

(2005), Vol. 65, pp. 4520-4524, Cancer research, Philadelphia, Pa., C1-1

journal article

Metabolism and transport of oxazaphosphorines and the clinical implications

J Zhang, Q Tian, Y Sui, C Shu, S Zhou, W Duan, Y Zhu

(2005), Vol. 37, pp. 611-703, Drug metabolism reviews, Abingdon, Eng., C1-1

journal article

Effects of purified herbal extract of Saliva miltiorrhiza on ischemic rat myocardium after acute myocardial infarction

J Sun, S Huang, B Tan, M Whiteman, Y Zhu, Y Wu, Y Ng, W Duan, Y Zhu

(2005), Vol. 76, pp. 2849-2860, Life sciences, Amsterdam, The Netherlands, C1-1

journal article

The last five amino acid residues at the C-terminus of PRK1 /KKN is essential for full lipid responsiveness

W Lim, Y Zhu, C Wang, B Tan, J Armstrong, T Dockland, H Yang, Y Zhu, T Teo, W Duan

(2005), Vol. 17, pp. 1084-1097, Cellular signalling, New York, N.Y., C1-1

journal article

Prediction of herb-drug metabolic interactions: a simulation study

S Zhou, M Huang, A Xu, H Yang, W Duan, J Paxton

(2005), Vol. 19, pp. 464-471, Phytotherapy research: an international journal devoted to mekical and scientific research on plants and plant products, Chichester, England, C1-1

journal article

Simultaneous determination of the lactone and carboxylate forms of irintecan (CPT-11) and its actie metabolite SN-38 by high-performance liquid chromatography: Application to plasma pharmacokinetic studies in the rat.

X Yang, Z Hu, S Chan, B Goh, W Duan, E Chan, S Zhou

(2005), Vol. 821, pp. 221-228, Journal of chromatography. B, analytical technologies in the biomedical and life sciences, Amsterdam, The Netherlands, C1-1

journal article

Molecular characterization of Osh6p, an oxysterol binding protein homolog in the yeast Saccharomyces cerevisiae

P Wang, W Duan, A Munn, H Yang

(2005), Vol. 272, pp. 4703-4715, FEBS journal, London, England, C1-1

journal article

Influence of pulsed electromagnetic field with different pulse duty cycles on neurite outgrowth in PC12 rat pheochromocytoma cells

Y Zhang, J Ding, W Duan, W Fan

(2005), Vol. 26, pp. 406-411, Bioelectromagnetics, New York, N.Y., C1-1

journal article

Human multidrug resistance associated protein 4 resitance to camtothecins

Q Tian, J Zhang, T Tan, E Chan, W Duan, S Chan, U Boelsterli, P Ho, H Yang, J Bian, M Huang, Y Zhu, W Xiong, X Li, S Zhou

(2005), Vol. 22, pp. 1837-1853, Pharmaceutical research, New York, N.Y., C1-1

journal article

Alteration of the pharmacokinetics of COL-3, a matrix metalloproteinase inhibitor, due to actue gastrointestinal tosicity of doxorubicin

J Li, S Zhou, H Huynh, W Duan, E Chan

(2005), Vol. 22, pp. 1954-1963, Pharmaceutical research, Delft, The Netherlands, C1-1

journal article

Antitumor activity and underlying mechamisms of ganopoly, the refined polysaccharides extracted from ganodrema lucidum, in mice

Y Gao, H Gao, E Chan, W Tang, A Xu, H Yang, M Huang, J Ln, X Li, W Duan, C Xu, S Zhou

(2005), Vol. 34, pp. 171-198, Immunological investigations: a journal of molecular and cellular immunology, New York, N.Y., C1-1

journal article

Insights into exazaphosphorine resistance and possible approaches to its circumvention

J Zhang, Q Tian, S Chan, W Duan, S Zhou

(2005), Vol. 8, pp. 271-297, Drug resistance updates, Edinburgh, Scotland, C1-1

journal article

St Johns wort modulates the toxicities and parmacokinetics of CPT-11 (Irontecan) in rats

Z Hu, X Yang, P Ho, E Chan, S Chan, C Xu, X Li, Y Zhu, W Duan, X Chen, M Huang, H Yang, S Zhou

(2005), Vol. 22, pp. 902-914, Pharmaceutical research, Amsterdam, The Netherlands, C1-1

journal article

Determination of thalidomide by high performance liquid chromatography: plasma pharmacokinetic studies in the rat

X Yang, Z Hu, S Chan, P Ho, E Chan, W Duan, B Goh, S Zhou

(2005), Vol. 39, pp. 299-304, Journal of pharmaceutical and biomedical analysis, Amsterdam, The Netherlands, C1-1

journal article

Herb-drug interactions: a literature review

Z Hu, X Yang, P Ho, S Chan, P Heng, E Chan, W Duan, H Koh, S Zhou

(2005), Vol. 65, pp. 1239-1282, Drugs, Auckland, New Zealand, C1-1

journal article

Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs

S Zhou, S Chan, B Goh, E Chan, W Duan, M Huang, H McLeod

(2005), Vol. 44, pp. 279-304, Clinical pharmacokinetics, Auckland, New Zealand, C1-1

journal article

Drug bioactivation, covalent binding to target proteins and toxicity relevance

S Zhou, E Chan, W Duan, M Huang, Y Chen

(2005), Vol. 37, pp. 41-213, Drug metabolism reviews, New York, N.Y., C1-1

journal article

Inhaled p38a mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice

W Duan, J Chan, K McKay, J Crosby, H Choo, B Leung, J Karras, W Wong

(2005), Vol. 171, pp. 571-578, American journal of respiratory and critical care medicine, New York, N.Y., C1-1

journal article

Multidrug resistance proteins (MRPs) and implication in drug development

Q Tian, J Zhang, E Chan, W Duan, S Zhou

(2005), Vol. 64, pp. 1-18, Drug development research, New York, N.Y., C1-1

journal article

An anti-inflammatory role for a phosphoinositide 3-kinase inhibitor LY294002 in a mouse asthma model

W Duan, A Aguinaldo Datiles, B Leung, C Vlahos, W Wong

(2005), Vol. 5, pp. 495-502, International immunopharmacology, Amsterdam, The Netherlands, C1-1

journal article

The PKCa-D294G mutant found in pituitary and thyroid tumors fails to transduce extracellular signals

Y Zhu, Q Dong, B Tan, W Lim, S Zhou, W Duan

(2005), Vol. 65, pp. 4520-4524, Cancer research, Philadelphia, Pa., C1-1

journal article

Novel agents that potentially inhibit irinotecan-induced diarrhea

X Yang, Z Hu, S Chan, E Chan, B Goh, W Duan, S Zhou

(2005), Vol. 12, pp. 763-771, Current medicinal chemistry, Beijing, China, C1-1

journal article
2004

Effects of Salvia miltiorrhiza after acute myocardial infarction in rats

X Ji, B Tan, S Huang, M Whiteman, Y Zhu, W Duan, Y Zhu, W Linz

(2004), pp. 183-195, Novel compounds from natural products in the new millennium, Singapore, B1-1

book chapter

Signaling via a novel integral plasma membrane pool of a serine/threonine protein kinase PPKI in mammalian cells

Y Zhu, D Stolz, F Guo, M Ross, S Watkins, B Tan, R Qi, E Manser, Q Li, B Bay, T Teo, W Duan

(2004), Vol. 18, pp. 1722-1724, The FASEB journal : official publication of the Federation of American Societies for experimental biology, Bethesda, Md., C1-1

journal article

The influence of magnetic fields exposure on neurite outgrowth in PC12 rat pheochromocytoma cells

W Fan, J Ding, W Duan, Y Zhu

(2004), Vol. 282, pp. 325-328, Journal of magnetism and magnetic materials, Amsterdam, The Netherlands, C1-1

journal article

Cytochrome bc1 regulates the mitochondrial permeability transition by two distinct pathways

J Armstrong, H Yang, W Duan, M Whiteman

(2004), Vol. 279, pp. 50420-50428, Journal of biological chemistry, Bethesda, Md., C1-1

journal article

Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor U0126 in an asthma mouse model

W Duan, J Chan, C Wong, B Leung, W Wong

(2004), Vol. 172, pp. 7053-7059, Journal of immunology, Rockville, Md., C1-1

journal article

Inhibitor of p42/44 mitogen-activated protein kinase, but not p38 MAPK, attenuated antigen challenge of guinea pig airways in vitro

S Chue, C Seow, W Duan, K Yeo, A Koh, W Wong

(2004), Vol. 4, pp. 1089-1098, International immunopharmacology, Amsterdam, The Netherlands, C1-1

journal article
2003

Antiinflammatory effects of genistein, a tyrosine kinase inhibitor, on a guinea pig model of asthma

W Duan, I Kuo, S Selvarajan, K Chua, B Bay, W Wong

(2003), Vol. 167, pp. 185-192, American journal of respiratory and critical care medicine, New York, N.Y., C1-1

journal article
2002

Metallothionein 2A expression is associated with cell proliferation in breast cancer

R Jin, V Chow, P Tan, S Dheen, W Duan, B Bay

(2002), Vol. 23, pp. 81-86, Carcinogenesis, Oxford, England, C1-1

journal article
2001

Identification of two proteins, S14 and UIP1, that interact with UCH37

T Li, W Duan, H Yang, M Lee, F Mustafa, B Lee, T Teo

(2001), Vol. 488, pp. 201-205, FEBS letters, Amsterdam, The Netherlands, C1-1

journal article
2000

Cloning and characterization of AWP1, a novel protein that associates with serine/threonine kinase PRK1 in vivo

W Duan, B Sun, T Li, B Tan, M Lee, T Teo

(2000), Vol. 256, pp. 113-121, Gene, Amsterdam, The Netherlands, C1-1

journal article
1995

Wallaby transthyretin

C Brack, W Duan, A Hulbert, G Schreiber

(1995), Vol. 110, pp. 523-529, Comparative biochemistry and physiology - part b: biochemistry & molecular biology, Amsterdam, The Netherlands, C1-1

journal article

Binding of thyroxine to pig transthyretin, its cDNA structure, and other properties

W Duan, S Richardson, J Kohrle, L Chang, B Southwell, P Harms, C Brack, T Pettersson, G Schreiber

(1995), Vol. 230, pp. 977-986, European journal of biochemistry, Chichester, Eng., C1-1

journal article

Homozygous deletions of the multiple tumor suppressor gene 1 in the progression of human astrocytomas

D Walker, W Duan, E Popovic, A Kaye, F Tomlinson, M Lavin

(1995), Vol. 55, pp. 20-23, Cancer research, Philadelphia, Pa., C1-1

journal article

Evolution of transthyretin in marsupials

W Duan, S Richardson, J Babon, R Heyes, B Southwell, P Harms, R Wettenhall, K Dziegielewska, L Selwood, A Bradley, C Brack, G Schreiber

(1995), Vol. 227, pp. 396-406, European journal of biochemistry, Chichester, Eng., C1-1

journal article
1994

Evolution of marsupial and other vertebrate thyroxine-binding plasma proteins

S Richardson, A Bradley, W Duan, R Wettenhall, P Harms, J Babon, B Southwell, S Nicol, S Donnellan, G Schreiber

(1994), Vol. 266, pp. R1359-R1370, American journal of physiology. Regulatory, integrative and comparative physiology, Bethesda, Md., C1-1

journal article
1993

The Expression of the Transthyretin Gene in Liver Evolved during the Radiation of Diprotodont Marsupials in Australia

S Richardson, A Bradley, W Duan, B Southwell, L Selwood, G Schreiber

(1993), Vol. 90, pp. 177-182, General and Comparative Endocrinology, New York, N.Y., C1-1

journal article

Thyroxine Transport to the Brain: Role of Protein Synthesis by the Choroid Plexus

B Southwell, W Duan, D Alcorn, C Brack, S Richardson, J Kohrle, G Schreiber

(1993), Vol. 133, pp. 2116-2126, Endocrinology, Oxford, Eng., C1-1

journal article

Transthyretin gene expression in choroid plexus first evolved in reptiles

M Achen, W Duan, T Pettersson, P Harms, S Richardson, M Lawrence, R Wettenhall, A Aldred, G Schreiber

(1993), Vol. 265, pp. R982-R989, American Journal of Physiology, Bethesda, Md., C1-1

journal article
1992

Expression of retinol-binding protein mRNA in mammalian choroid plexus

W Duan, G Schreiber

(1992), Vol. 101, pp. 399-406, Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology, Amsterdam, The Netherlands, C1-1

journal article
1991

Ontogenesis of transthyretin gene expression in chicken choroid plexus and liver

B SOUTHWELL, W DUAN, G TU, G SCHREIBER

(1991), Vol. 100, pp. 329-338, Comparative biochemistry and physiology part B: Comparative biochemistry, Amsterdam, The Netherlands, C1-1

journal article

Isolation, characterization, cDNA cloning and gene expression of an avian transthyretin: implications for the evolution of structure and function of transthyretin in vertebrates Isolation, characterization, cDNA cloning and gene

W DUAN, M ACHEN, S RICHARDSON, M LAWRENCE, R WETTENHALL, A JAWOROWSKI, G SCHREIBER

(1991), Vol. 200, pp. 679-687, European journal of biochemistry, Chichester, Eng., C1-1

journal article

Funded Projects at Deakin

Australian Competitive Grants

A novel tumour-targeting nanoliposome drug delivery system for the treatment of malignant gliomas

Prof Wei Duan, A/Prof Andrew Danks, Prof Sing Lo, A/Prof Qiu Tian Li

NHMRC Project Grant

  • 2010: $171,350
  • 2009: $168,157
  • 2008: $105,590

Developing molecularly targeted polymer nanoparticles for cancer therapeutics and diagnostics

Prof Wei Duan, Prof Qipeng Guo

DIISR/AISRF Grant - AISRF/India-Australian Strategic Research Fund - Department of Innovation, Industry, Science & Research

  • 2010: $29,200
  • 2009: $82,019
  • 2007: $210,000

Smart bombing of cancer stem cells using aptamer-guided nanoliposomal siRNA

Prof Wei Duan, Prof Lingxue Kong

DIISR/AISRF Grant - AISRF/India-Australian Strategic Research Fund - Department of Innovation, Industry, Science & Research

  • 2013: $75,000
  • 2012: $68,000
  • 2011: $112,000
  • 2010: $145,000

Peptide-based Star Nanocarriers for Targeted Anticancer Drug Delivery

Prof Greg Qiao, Prof Wei Duan, Prof Kenneth Dawson

ARC - Discovery Projects

  • 2016: $121,661
  • 2015: $54,996

Collaborative workshop on MEMS and its application in health care

Prof Lingxue Kong, Prof Wei Duan, Prof Abbas Kouzani, Prof Johnson Mak, Dr Sugumar Dharmalingam

DIISR/AISRF Grant - AISRF/India-Australian Strategic Research Fund - Department of Innovation, Industry, Science & Research

  • 2014: $31,000

Synthetic ligand-based intraoperative diagnostic platform for surgical pathology

Prof Wei Duan, Prof Jiake Xu, Mr Songxi Xiang

Department of Education Australias Economic Accelerator Seed Grants

  • 2024: $160,000

Other Public Sector Funding

Link and Learn Grant

Prof Wei Duan

DHSV Victorian Cancer Agency - Department of Human Services Victoria

  • 2008: $5,000

Establishment of an aptamer-based technology platform for molecular targetting of cancer stem cell

Prof Wei Duan, A/Prof Andrew Danks, A/Prof Q Dong, Prof Lingxue Kong, A/Prof Jun-Ping Liu, Dr Jane Dai, Prof Michael Famulok, Prof Dominique Joubert

DHSV Victorian Cancer Agency - Department of Human Services Victoria

  • 2008: $136,346

Equipment Grant 2007

Prof Wei Duan

NHMRC - Equipment Grant (pre 2017)

  • 2008: $81,082

Industry and Other Funding

Establishment of the First Medical School in Geelong

Prof Wei Duan, Prof Alister Ward, Prof Brendan Crotty

Geelong Community Foundation Grant - Research

  • 2007: $30,000

Novel therapeutics to root out cancer

Prof Wei Duan

CASS Grant - Research - The CASS Foundation Limited

  • 2014: $15,000
  • 2013: $40,000

Tailored Neoadjuvant Epirubicin and Cyclophosphamide (EC) and Nanoparticle Albumin Bound (nab) Paclitaxel for Newly Diagnosed Breast Cancer

Dr Mustafa Khasraw, Prof Wei Duan

Specialised Therapeutics Australia Pty. Ltd

  • 2014: $66,500
  • 2013: $50,000

Glycomarker Panel for Prediction of IVF Outcome

Tracey Edgell, Prof Wei Duan

Merck Serono - Grant for Fertility Innovation GFI

  • 2017: $1,000
  • 2016: $56,618
  • 2015: $55,043

Research into the role of Proteins called cytokine receptors in ovarian cancer and the development of novel agents to suppress their effects

Prof Alister Ward, Prof Wei Duan, Dr Daniel Mcculloch

Equity Trustees - Norman, Ann & Graeme Atkins Charitable Trust

  • 2015: $12,500
  • 2014: $12,500
  • 2013: $12,500

Development of nanoparticle-based delivery systems for Artemisia flavonoids for the treatment of hepatitis B

Prof Wei Duan

The Xingjian Institute of Materia Medic

  • 2018: $495
  • 2017: $31,114

Development of novel aptamer-guided and exosome-based diagnostics and therapeutics

Prof Wei Duan

Suzhou Genepharma Co., Ltd.

  • 2019: $80,000
  • 2018: $79,970
  • 2017: $80,000

Shanghai OneTar-Deakin Joint Laboratory of Personalised Precision Medicine.

Prof Wei Duan

Shanghai OneTar Biomedicine

  • 2023: $40,000
  • 2021: $70,000

Supervisions

Principal Supervisor
2023

Rocky Chowdhury

Thesis entitled: Development of CD9 Aptamer for sEV-based Liquid Biopsy

Doctor of Philosophy (Medicine), School of Medicine

Shweta Shashikant Patel

Thesis entitled: Aptamer-Based Molecular Pathology of Cancer

Doctor of Philosophy (Medicine), School of Medicine

2022

Tuong Ngoc Gia Nguyen

Thesis entitled: Blueberry-derived extracellular vesicles as a novel nanobioplatform for immunotherapy

Doctor of Philosophy (Medicine), School of Medicine

Viet Pham

Thesis entitled: Small affinity probes for extracellular nanovesicle-based cancer liquid biopsy

Doctor of Philosophy (Medicine), School of Medicine

Mohammed Mehadi Hassan Chowdhury

Thesis entitled: PVA Coated Doxorubicin Loaded Zinc Ferrite Nanoparticles Against Liver Cancer

Doctor of Philosophy (Medicine), School of Medicine

2021

Snehal Midge

Thesis entitled: Novel aptamers against HER-2 for liquid biopsy

Doctor of Philosophy (Medicine), School of Medicine

2020

Hridika Talukder Barua

Thesis entitled: Development of a novel exosome-based liquid biopsy assay for early detection of pancreatic cancer

Doctor of Philosophy (Medicine), School of Medicine

Yumei Zhang

Thesis entitled: Development of CD81 aptamers for extracellular vesicle-based theranostics

Doctor of Philosophy (Medicine), School of Medicine

2018

Wang Yin

Thesis entitled: Novel strategies to overcome drug resistance in liver cancer

Doctor of Philosophy (Medicine), School of Medicine

2016

Hadi Al Shamaileh

Thesis entitled: Aptamer-mediated siRNA delivery to target colon cancer stem cells

Doctor of Philosophy (Medicine), School of Medicine

2015

Dongxi Xiang

Thesis entitled: Developing RNA aptamer technology for targeting cancer stem cells

Doctor of Philosophy (Medicine), School of Medicine

2014

Tao Wang

Thesis entitled: An aptamer-mediated siRNA delivery system targeting breast tumourigenic cells

Doctor of Philosophy (Medicine), School of Medicine

Manju Marappan

Thesis entitled: Efficacy of utilizing chemical antibodies in histopathological studies

MAppSc (Medicine) (High cost), School of Medicine

2013

Jia Lin

Thesis entitled: A nanoliposome-based drug delivery system for cancer

Doctor of Philosophy (Medicine), School of Medicine

2010

Michael Stewart

Thesis entitled: Molting and Reproduction in Portunus Pelagicus

Doctor of Philosophy (Medicine), School of Medicine

Associate Supervisor
2023

Yugandhar Arcot

Thesis entitled: Fabrication of polymeric microfluidic devices for blood plasma separation

Doctor of Philosophy (Engineering), Institute for Frontier Materials

2022

Yajie Dong

Thesis entitled: Wet Spun Graphene/Polyurethane Fibres for Triboelectric Nanogenerators

Doctor of Philosophy (Engineering), Institute for Frontier Materials

2021

Jianyang Zhao

Thesis entitled: Multi-Responsive Polymeric Biomaterials for Biomedical Applications

Doctor of Philosophy (Engineering), Institute for Frontier Materials

2020

Hao Fang

Thesis entitled: The role of IL-6 family signalling components in ovarian cancer

Doctor of Philosophy (Medicine), School of Medicine

2017

Joanna Michelle Macdonald

Thesis entitled: A bifunctional aptamer for the targeted treatment of brain metastases

Doctor of Philosophy (Medicine), School of Medicine

Xinchu Zhao

Thesis entitled: Gold Nanoparticles Based DNA Detection in Microfluidics

Doctor of Philosophy (Engineering), Institute for Frontier Materials

2016

Lijue Chen

Thesis entitled: Delivery of Fluorouracil and siRNA by Mesoporous Silica Nanoparticles to Drug Resistant Colorectal Cancer

Doctor of Philosophy (Engineering), Institute for Frontier Materials

2015

Xiaodong She

Thesis entitled: Tailored hollow mesoporous silica nanoplatforms with biological labels for colon targeted drug deliver systems

Doctor of Philosophy (Engineering), Institute for Frontier Materials

2014

Daryoush Mortazavi

Thesis entitled: DESIGN, MODELLING, FABRICATION, AND EVALUATION OF A TUNEABLE LSPR DEVICE

Doctor of Philosophy (Engineering), School of Engineering

2012

Yang Lim

Thesis entitled: Surface-Stress-Based Microcantilever Aptasensor

Doctor of Philosophy (Engineering), School of Engineering