Prof Wei Duan

STAFF PROFILE

Position

Alfred Deakin Professor

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Contact

wei.duan@deakin.edu.au
+61 3 522 71149

Research interests

Professor Duan's research focuses on developing nucleic acid aptamer technology platforms for cancer biotechnology, focusing on cancer stem cell-targeted drug, siRNA and miRNA delivery using nanoparticles as well as aptamer-based molecular imaging for early detection of cancer and accurate staging. He heads a cross-disciplinary and translational research team consisting of cancer biologists, oncologists, molecular and cell biologists, material scientists, organic chemists, drug developers, pharmaceutical scientists and mechanical and electronic engineers across several faculties, research centres and teaching hospitals in Deakin. He is also involved in developing novel aptamer-based and microfluidic lab-on-a-chip devices for the application in biodefense, forensic medicine and rapid diagnostics at the point of care. He has published over 160 peer-reviewed original research papers and review articles in international refereed journals, with an h-index of 30 (average citation per article of 25).  Professor Duan has filed 5 international patents on cancer stem related aptamers.  He serves as the Editor-in-Chief for the journal “Drug Design, Development and Therapy” (https://www.dovepress.com/drug-design-development-and-therapy-journal).


Professors Duan has been frequently invited to address international conferences on biomedical research, drug development and molecular medicine.

6. Wei Duan, “Aptamer therapeutics: the 21st century’s magic bullet of nanomedicine”, Second International Conference on Drug Discovery and Therapy'. Feb 1-4, 2010. Dubai, United Arab Emirates.

8. Wei Duan,  RNA Aptamer: The Next Generation of Cancer Stem Cell-targeted Molecular Imaging,  BIT’s 9th Annual Congress of International Drug Discovery Science and Technology, Nov 3-6, 2011, Shenzhen, China;

10. Wei Duan, RNA aptamer-guided nanodrug delivery for the 21st century cancer medicine, 6th Annual Meeting of the Australian chapter of the Controlled Release Society, Melbourne, Nov 26-27, 2012.

11. Wei Duan, “Aptamer-guided nano drug delivery systems for cancer therapy”, Nano- and Microparticle-based drug and vaccine delivery, The 6th Joint Australia-New Zealand chapters of the Controlled Release Society, Brisbane, July 4-5, 2013.

12. W. Duan, “The use of RNA aptamers for diagnosis: detecting low levels of EpCAM in paraffin embedded tissues“, Aptamer in Medicine and Perspectives, Oct 4-5, 2013, Naples, Italy.

13. D.Xiang. S. Shigdar, W. Duan, “Targeting cancer stem cells in vivo using RNA aptamers“, 16th International Symposium on Molecular Medicine/The 18th World Congress on Advances in Oncology, 10-12, October, 2013, Hotel Creta Maris Resort, Greece.

15. T Wang, S Shigdar, Wei Duan, “An aptamer-based siRNA in vivo delivery system targeting cancer stem cells, 5th FIP Pharmaceutical Sciences World Congress, Melbourne, Australia, April 13-16, 2014.

16. Shigdar S, Xiang D, Duan W. Aptamers as effective cancer stem cell targeting modalities. Aptamers- 2014, 24-25th March 2014, Oxford, UK. Aug 25-27, 2015.

17. Wei Duan, “Cancer stem cells targeted delivery of siRNA in vivo: translating Nobel Prize-winning technology to clinic”, 8th Dubai International Conference for Medical Sciences, Ded15-17, 2014, Dubai, United Arab Emirates. 

18. Wei Duan, “Cancer stem cell targeted delivery of siRNA to overcome induced chemoresistance”, European Pharma Congress, Aug 25-27, 2015, Valencia, Spain.

19. Wei Duan, “RNA aptamer-guided in vivo RNAi to overcome chemoresistance”, Health forum of the Silk Road-Int Summit Forum of Research and Development on Traditional Chinese Medicine and Ethnic Medicine, Oct 17-18, 2015, Kunlun Hotel, Urumuqi, Xingjiang, P.R. China.

Knowledge areas

aptamer, chemical antibody, molecular cell bioogy, cancer stem cell, targeted drug delivery, nanomedicine, nanotechnology, novel cancer treatment and diagnostics

Conferences

Invited addresses: 1. Wei Duan, A Novel Paradigm in Mammalian Cell Signaling, Signal TransductionTargets for effective therapeutics, Cambridge Healthtech Institute, Seaport Hotel, Boston, MA, USA, November 8-9, 2004. [My talk was reviewed in Rounding up the usual suspects: protein kinases as the therapeutic targets, S.B. Shears, Drug Discovery Today.10(4):240-242, 2005.] 2. Wei Duan, Signaling via a novel integral plasma membrane pool of protein kinase C, The Hunter Meeting of Cell Biology, Sydney, Australia, 6-8 April, 2005. 3. Wei Duan, Herbal Medicine In AustraliaTransforming Ancient Remedy With Nanotechnology, 59th Indian Pharmaceutical Congress, Varanasi-221 005, Uttar Pradesh, India, 20-23 December, 2007. 4. Wei Duan, Development of Molecular Medicine that Specifically Targets Protein Kinase C in Heart Failure, 10th South China International Congress of Cardiology, Dongfang Hotel, Guangzhou, China, 10-13, April, 2008. 5. Wei Duan, Targeted drug delivery using RNA aptamer and nanoparticlesthe miracle of nanomedicine for the 21st century. VII Thailand Research Fund (TRF) Annual Congress. October 16-18, 2008, Holiday Inn Resort Regent Beach, Cha-Am, Thailand. 6. Wei Duan, Aptamer therapeutics: the 21st centurys magic bullet of nanomedicine, Second International Conference on Drug Discovery and Therapy'. February 1-4, 2010. Dubai, United Arab Emirates. 7. Wei Duan, Nucleic acid aptamer: the pearl in the crown of nanomedicine for molecular imaging of cancer, The 4th International Symposium on Bioanalysis, Biomedical Engineering and Nanotechnology (ISBBN 2010), Hunan University in Changsha, Hunan, China (June 3-6, 2010). 8. Wei Duan, RNA Aptamer: The Next Generation of Cancer Stem Cell-targeted Molecular Imaging, BITs 9th Annual Congress of International Drug Discovery Science and Technology --- Re-think Drug Innovations in Green-Eco Era (Session 7-1-2: Nucleic Acid Therapeutics), November 3-6, 2011, Shenzhen, China.

Media appearances

Being an Australian leader in developing aptamers against cancer stem cells,  Professor Duan is well recognised for his innovative and translational medical research.  For example, his work of developing RNA aptamer for cancer diagnosis and treatment was cited by Senator Kim Carr (Minister for Innovation), in his press release on 7 January 2011 as a fine example of the world-class research carried out by Australian leading researchers funded by the Department of Innovation, Industry, Science and Research, Australian Government.
(http://www.industry.gov.au/science/internationalcollaboration/Documents/Cancer_Diagnostics_Case_Study.pdf)

In addition, Professor Duan’s work has enjoined wide coverage by both domestic and international media (for a TV interview: http://www.youtube.com/watch?feature=player_embedded&v=cn_up61UnQY#at=244).

Newspaper coverage of Professor Duan's research:
1) The Australian newspaper, March 19, 2011, Article by Reporter Alexander Gambotto-Burke.
2) The Age newspaper, Melbourne: July 5, 2010,  Article by Reporter Danny Rose. 

3) Australian Broadcast Corporation, National Australia Radio, March 11, 2011, Interview with Desley Blanch.
4)  Australian Broadcast Corporation, Melbourne Radio, February 17 (17:35), Prime time Interview with Lindy Burns.
5)  Victoria TV Channel 31: Special features at 18:30, 9 March 2011, Length: 7 min 42 sec.
6)  Geelong Advertiser: July 6, 2010, Article by Reporter Joel Cresswell.
7)  Geelong Independent: February 25, 2011, Article by Erin Pearson.

Publications

Filter by

2020

Development of conjugate-by-conjugate structured nanoparticles for oral delivery of docetaxel

P Ha-Lien Tran, T Wang, C Yang, T Tran, W Duan

(2020), Vol. 107, Materials science and engineering c, Amsterdam, The Netherlands, C1

journal article

Fucoidan-based nanostructures: A focus on its combination with chitosan and the surface functionalization of metallic nanoparticles for drug delivery

P Tran, W Duan, T Tran

(2020), Vol. 575, pp. 1-8, International Journal of Pharmaceutics, Amsterdam, The Netherlands, C1

journal article

Current perspectives on delivery systems using extracellular vesicles in neurological disease

P Tran, W Duan, B Lee, T Tran

(2020), Vol. 26, pp. 764-771, Current pharmaceutical design, Sharjah, United Arab Emirates, C1

journal article

CD44 variant 6 is associated with prostate cancer growth and chemo-/radiotherapy response in vivo

J Ni, B Cheung, J Beretov, W Duan, J Bucci, D Malouf, P Graham, Y Li

(2020), Vol. 388, pp. 1-7, Experimental Cell Research, Amsterdam, The Netherlands, C1

journal article

Aptamer-guided extracellular vesicle theranostics in oncology

P Tran, D Xiang, T Nguyen, T Tran, Q Chen, W Yin, Y Zhang, L Kong, A Duan, K Chen, M Sun, Y Li, Y Hou, Y Zhu, Y Ma, G Jiang, W Duan

(2020), Vol. 10, pp. 3849-3866, Theranostics, Sydney, N.S.W., C1

journal article

Neuroprotective effect of phthalide derivative CD21 against ischemic brain injury:involvement of MSR1 mediated DAMP peroxiredoxin1 clearance and TLR4 signaling inhibition

X Zou, X Yang, Y Gan, D Liu, C Chen, W Duan, J Du

(2020), pp. 1-12, Journal of neuroimmune pharmacology, New York, N.Y., C1

journal article
2019

Development of a novel drug targeting delivery system for cervical cancer therapy

Li Xiao, Ni Ma, Huimin He, Jinmei Li, Sinan Cheng, Qian Yang, Yifan Hou, Fengying Song, Huijuan Jin, Xiaorong Su, Jing Dong, Ruiye Zuo, Xigui Song, Wei Duan, Yingchun Hou

(2019), Vol. 30, pp. 1-16, Nanotechnology, Bristol, Eng., C1

journal article

A detailed protein-SELEX protocol allowing visual assessments of individual steps for a high success rate

Tao Wang, Wang Yin, Hadi AlShamaileh, Yumei Zhang, Phuong Tran, Tuong Nguyen, Yong Li, Kuisheng Chen, Miaomiao Sun, Yingchun Hou, Weihong Zhang, Qingxia Zhao, Changying Chen, Pei-Zhuo Zhang, Wei Duan

(2019), Vol. 30, pp. 1-16, Human gene therapy methods, New Rochelle, N.Y., C1

journal article

Lentiviral vector-mediated overexpression of Klotho in the brain improves Alzheimer's disease-like pathology and cognitive deficits in mice

Chen-Ye Zeng, Ting-Ting Yang, Hong-Jing Zhou, Yue Zhao, Xi Kuang, Wei Duan, Jun-Rong Du

(2019), Vol. 78, pp. 18-28, Neurobiology of aging, Amsterdam, The Netherlands, C1

journal article

Annexin A2 enhances the progression of colorectal cancer and hepatocarcinoma via cytoskeleton structural rearrangements

Huimin He, Li Xiao, Sinan Cheng, Qian Yang, Jinmei Li, Yifan Hou, Fengying Song, Xiaorong Su, Huijuan Jin, Zheng Liu, Jing Dong, Ruiye Zuo, Xigui Song, Yanyan Wang, Kun Zhang, Wei Duan, Yingchun Hou

(2019), pp. 1-11, Microscopy and microanalysis, Cambridge, Eng., C1

journal article

The use of zein in the controlled release of poorly water-soluble drugs

Phuong Tran, Wei Duan, Beom-Jin Lee, Thao Tran

(2019), Vol. 566, pp. 557-564, International journal of pharmaceutics, Amsterdam, The Netherlands, C1

journal article

Development of a nanoamorphous exosomal delivery system as an effective biological platform for improved encapsulation of hydrophobic drugs

Phuong Tran, Tao Wang, Wang Yin, Thao Tran, Hridika Barua, Yumei Zhang, Snehal Midge, Tuong Nguyen, Beom-Jin Lee, Wei Duan

(2019), Vol. 566, pp. 697-707, International journal of pharmaceutics, Amsterdam, The Netherlands, C1

journal article

Nanogels for skin cancer therapy via transdermal delivery: current designs

P Tran, W Duan, B Lee, T Tran

(2019), Vol. 20, pp. 575-582, Current drug metabolism, Beijing, China, C1

journal article

Modulation of drug crystallization and molecular interactions by additives in solid dispersions for improving drug bioavailability

P Tran, W Duan, B Lee, T Tran

(2019), Vol. 25, pp. 2099-2107, Current pharmaceutical design, Beijing, China, C1

journal article

Drug stabilization in the gastrointestinal tract and potential applications in the colonic delivery of oral zein-based formulations

P Tran, W Duan, B Lee, T Tran

(2019), Vol. 569, pp. 1-6, International journal of pharmaceutics, Amsterdam, The Netherlands, C1

journal article

Exosomes and nanoengineering: a match made for precision therapeutics

Phuong Tran, Dongxi Xiang, Thao Tran, Wang Yin, Yumei Zhang, Lingxue Kong, Kuisheng Chen, Miaomiao Sun, Yong Li, Yingchun Hou, Yimin Zhu, Wei Duan

(2019), Advanced materials, Weinheim, Germany, C1

journal article

Recent developments of nanoparticle-delivered dosage forms for buccal delivery

P Tran, W Duan, T Tran

(2019), Vol. 571, pp. 1-7, International journal of pharmaceutics, Amsterdam, The Netherlands, C1

journal article

Aspirin-loaded nanoexosomes as cancer therapeutics

P Tran, T Wang, W Yin, T Tran, T Nguyen, B Lee, W Duan

(2019), Vol. 572, pp. 1-12, International Journal of Pharmaceutics, Amsterdam, The Netherlands, C1

journal article
2018

Tailored mesoporous silica nanoparticles for controlled drug delivery: platform fabrication, targeted delivery, and computational design and analysis

X She, L Chen, Z Yi, C Li, C He, C Feng, T Wang, S Shigdar, W Duan, L Kong

(2018), Vol. 16, pp. 976-989, Mini-reviews in medicinal chemistry, Beijing, China, C1

journal article

Encapsulation of solid dispersion in solid lipid particles for dissolution enhancement of poorly water-soluble drug

K Tran, T Vo, B-J Lee, W Duan, P Tran, T Tran

(2018), Vol. 15, pp. 576-584, Current drug delivery, Beijing, China, C1

journal article

Aptamers as potential therapeutic agents for ovarian cancer

J Henri, J Macdonald, M Strom, W Duan, S Shigdar

(2018), Vol. 145, pp. 34-44, Biochimie, Amsterdam, The Netherlands, C1

journal article

Mesoporous silica nanorods toward efficient loading and intracellular delivery of siRNA

L Chen, X She, T Wang, S Shigdar, W Duan, L Kong

(2018), Vol. 20, pp. 1-13, Journal of nanoparticle research, Cham, Switzerland, C1

journal article

Switching off the interactions between graphene oxide and doxorubicin using vitamin C: combining simplicity and efficiency in drug delivery

Z Liu, J Liu, T Wang, Q Li, P Francis, C Barrow, W Duan, W Yang

(2018), Vol. 6, pp. 1251-1259, Journal of materials chemistry B, Cambridge, Eng., C1

journal article

Aptamers as targeting ligands and therapeutic molecules for overcoming drug resistance in cancers

G Zhou, O Latchoumanin, L Hebbard, W Duan, C Liddle, J George, L Qiao

(2018), Vol. 134, pp. 107-121, Advanced drug delivery reviews, Amsterdam, The Netherlands, C1

journal article

Encapsulation of solid dispersion in solid lipid particles for dissolution enhancement of poorly water-soluble drug

Thi Khanh, Van Toi, Beom-Jin Lee, Wei Duan, Ha-Lien Phuong, Truong-Dinh Thao

(2018), Vol. 15, pp. 576-584, Current drug delivery, Beijing, China, C1

journal article

Current designs of polymer blends in solid dispersions for improving drug bioavailability

Phuong Tran, Wei Duan, Beom-Jin Lee, Thao Tran

(2018), Vol. 19, pp. 1111-1118, Current drug metabolism, Beijing, China, C1

journal article

Epithelial cell adhesion molecule (EpCAM) is involved in prostate cancer chemotherapy/radiotherapy response in vivo

Jie Ni, Paul Cozzi, Julia Beretov, Wei Duan, Joseph Bucci, Peter Graham, Yong Li

(2018), Vol. 18, pp. 1-12, BMC cancer, London, Eng., C1

journal article

RNA aptamers-guided precision cancer medicine

W Duan, T Wang, S Shigdar, P Tran

(2018), Vol. 63, pp. 529-535, BME6 2016 : 6th International Conference on the Development of Biomedical Engineering in Vietnam, Ho Chi Minh City, Vietnam, E1

conference
2017

Challenges and opportunities for siRNA-based cancer treatment

T Wang, S Shigdar, H Al Shamaileh, M Gantier, W Yin, D Xiang, L Wang, S-F Zhou, Y Hou, P Wang, W Zhang, C Pu, W Duan

(2017), Vol. 387, pp. 77-83, Cancer letters, Shannon, Ireland, C1

journal article

Sonication-assisted nanoprecipitation in drug delivery

A Vo, T Luu, M Nguyen, T Vo, W Duan, P Tran, T Tran

(2017), Vol. 18, pp. 145-156, Current drug metabolism, Beijing, China, C1

journal article

Development of a bifunctional aptamer targeting the transferrin receptor and epithelial cell adhesion molecule (EpCAM) for the treatment of brain cancer metastases

J Macdonald, J Henri, L Goodman, D Xiang, W Duan, S Shigdar

(2017), Vol. 8, pp. 777-784, ACS chemical neuroscience, Washington, D.C., C1

journal article

Strategies of engineering nanoparticles for treating neurodegenerative disorders

P Tran, W Duan, K Nguyen, M Pham, T Vo, T Tran

(2017), Vol. 18, pp. 1-12, Current drug metabolism, Beijing, China, C1

journal article

Predictive value of UGT1A1*28 polymorphism in irinotecan-based chemotherapy

X-H Liu, J Lu, W Duan, Z-M Dai, M Wang, S Lin, P-T Yang, T Tian, K Liu, Y-Y Zhu, Y Zheng, Q-W Sheng, Z-J Dai

(2017), Vol. 8, pp. 691-703, Journal of cancer, Wyoming, N.S.W., C1

journal article

Nanotechnology in neuroscience and its perspective as gene carrier

T Khanh, W Duan, P Tran, T Tran

(2017), Vol. 17, pp. 1379-1389, Current topics in medicinal chemistry, Bussum, The Netherlands, C1-1

journal article

Effects of miR-29a and miR-101a expression on myocardial interstitial collagen generation after aerobic exercise in myocardial-infarcted rats

L Xiao, H He, L Ma, M Da, S Cheng, Y Duan, Q Wang, H Wu, X Song, W Duan, Z Tian, Y Hou

(2017), Vol. 48, pp. 27-34, Archives of medical research, Amsterdam, The Netherlands, C1

journal article

New pH-responsive gemini lipid derived co-liposomes for efficacious doxorubicin delivery to drug resistant cancer cells

P Moitra, K Kumar, S Sarkar, P Kondaiah, W Duan, S Bhattacharya

(2017), Vol. 53, pp. 8184-8187, Chemical communications, Cambridge, Eng., C1

journal article

Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells

H Al Shamaileh, T Wang, D Xiang, W Yin, P Tran, R Barrero, P-Z Zhang, Y Li, L Kong, K Liu, S-F Zhou, Y Hou, S Shigdar, W Duan

(2017), Vol. 7, pp. 1-9, Scientific reports, London, Eng., C1

journal article

Nano-sized solid dispersions based on hydrophobic-hydrophilic conjugates for dissolution enhancement of poorly water-soluble drugs

H Dinh, P Tran, W Duan, B-J Lee, T Tran

(2017), Vol. 533, pp. 93-98, International journal of pharmaceutics, The Netherlands, C1

journal article

Aptamer-based therapeutic approaches to target cancer stem cells

G Zhou, O Latchoumanin, M Bagdesar, L Hebbard, W Duan, C Liddle, J George, L Qiao

(2017), Vol. 7, pp. 3948-3961, Theranostics, Wyoming, N.S.W., C1

journal article

Transforming doxorubicin into a cancer stem cell killer via EpCAM aptamer-mediated delivery

D Xiang, S Shigdar, A Bean, M Bruce, W Yang, M Mathesh, T Wang, W Yin, P Tran, H Shamaileh, R Barrero, P Zhang, Y Li, L Kong, K Liu, S Zhou, Y Hou, A He, W Duan

(2017), Vol. 7, pp. 4071-4086, Theranostics, Sydney, N.S.W., C1

journal article

Nanoprecipitation for poorly water-soluble drugs

Tuong Nguyen, Van-Thanh Tran, Wei Duan, Phuong Tran, Thao Tran

(2017), Vol. 18, pp. 1000-1015, Current drug metabolism, Beijing, China, C1

journal article

Conjugation strategies for colonic delivery and its application in colorectal cancer therapy

P Tran, W Duan, T Tran

(2017), Vol. 18, pp. 1016-1019, Current drug metabolism, Beijing, China, C1

journal article

Aptamers and glioblastoma: their potential use for imaging and therapeutic applications

E Hays, W Duan, S Shigdar

(2017), Vol. 18, pp. 1-17, International journal of molecular sciences, Basel, Switzerland, C1

journal article
2016

Application of aptamers in histopathology

S Shigdar, L Lv, L Wang, W Duan

(2016), Vol. 1380, pp. 191-196, Nucleic acid aptamers : selection, characterization and application, New York, N.Y., B1

book chapter

Development of a sustained release solid dispersion using swellable polymer by melting method

T Nguyen, P Tran, T Van Vo, W Duan, T Tran

(2016), Vol. 33, pp. 102-109, Pharmaceutical research, Berlin, Germany, C1

journal article

Development of drug-loaded chitosan-vanillin nanoparticles and its cytotoxicity against HT-29 cells

P-W Li, G Wang, Z-M Yang, W Duan, Z Peng, L-X Kong, Q-H Wang

(2016), Vol. 23, pp. 30-35, Drug delivery, Abingdon, Eng., C1

journal article

The Application of aptamers for immunohistochemistry

M Bauer, J Macdonald, J Henri, W Duan, S Shigdar

(2016), Vol. 26, pp. 120-126, Nucleic acid therapeutics, New Rochelle, N.Y., C1

journal article

Aptamers: a promising chemical antibody for cancer therapy

G Zhou, G Wilson, L Hebbard, W Duan, C Liddle, J George, L Qiao

(2016), Vol. 7, pp. 13446-13463, Oncotarget, Albany, N.Y., C1

journal article

ANXA2 enhances the progression of hepatocellular carcinoma via remodeling the cell motility associated structures

H Shi, L Xiao, W Duan, H He, L Ma, M Da, Y Duan, Q Wang, H Wu, X Song, Y Hou

(2016), Vol. 85, pp. 26-33, Micron, Amsterdam, The Netherlands, C1

journal article

Perspectives of engineered marine derived polymers for biomedical nanoparticles

K Tran, T Vo, W Duan, P Tran, T Tran

(2016), Vol. 22, pp. 2844-2856, Current pharmaceutical design, Beijing, China, C1

journal article

An investigation of effects of modification processes on physical properties and mechanism of drug release for sustaining drug release from modified rice

V Ngo, T Luu, T Van Vo, V-T Tran, W Duan, P Tran, T Tran

(2016), Vol. 67, pp. 1-7, Materials science and engineering C, Amsterdam, The Netherlands, C1

journal article

Targeting epithelial-mesenchymal transition and cancer stem cells for chemoresistant ovarian cancer

J Deng, L Wang, H Chen, J Hao, J Ni, L Chang, W Duan, P Graham, Y Li

(2016), Vol. 7, pp. 55771-55788, Oncotarget, Orchard Park, N.Y., C1

journal article

Investigation of Fucoidan-oleic acid conjugate for delivery of Curcumin and Paclitaxel

U Phan, K Nguyen, T Vo, W Duan, P Tran, T TRAN

(2016), Vol. 16, pp. 1281-1287, Anti-cancer agents in medicinal chemistry, Beijing, China, C1

journal article

Truncation and mutation of a transferrin receptor aptamer enhance binding affinity

J Macdonald, P Houghton, D Xiang, W Duan, S Shigdar

(2016), Vol. 26, pp. 348-354, Nucleic acid therapeutics, New Rochelle, N.Y., C1

journal article

Inhibition of Aurora kinases induces apoptosis and autophagy via AURKB/p70S6K/RPL15 axis in human leukemia cells

S-J He, L-P Shu, Z-W Zhou, T Yang, W Duan, X Zhang, Z-X He, S-F Zhou

(2016), Vol. 382, pp. 215-230, Cancer letters, Amsterdam, The Netherlands, C1

journal article

Hydrophilic-hydrophobic polymer blend for modulation of crystalline changes and molecular interactions in solid dispersion

H Van Ngo, P Nguyen, T Van Vo, W Duan, V-T Tran, P Tran, T Tran

(2016), Vol. 513, pp. 148-152, International journal of pharmaceutics, Amsterdam, The Netherlands, C1

journal article

Proteomics discovery of chemoresistant biomarkers for ovarian cancer therapy

J Deng, L Wang, J Ni, J Beretov, V Wasinger, D Wu, W Duan, P Graham, Y Li

(2016), Vol. 13, pp. 905-915, Expert review of proteomics, Abingdon, Eng., C1

journal article

Proteomic identification of the lactate dehydrogenase A in a radioresistant prostate cancer xenograft mouse model for improving radiotherapy

J Hao, P Graham, L Chang, J Ni, V Wasinger, J Beretov, J Deng, W Duan, J Bucci, D Malouf, D Gillatt, Y Li

(2016), Vol. 7, pp. 74269-74285, Oncotarget, Albany, N.Y., C1

journal article

indium doped and carbon modified p25 nanocomposites with high visible-light sensitivity for the photocatalytic degradation of organic dyes

Z Jin, W Duan, W Duan, B Liu, X Chen, F Yang, J Guo

(2016), Vol. 517, pp. 129-140, Applied Catalysis A: General, Amsterdam, The Netherlands, C1-1

journal article
2015

Cytokine networks and cancer stem cells

C Liongue, A Ward, W Duan, S Shigdar

(2015), pp. 67-87, Cancer stem cells : emerging concepts and future perspectives in translational oncology, Berlin, Germany, B1

book chapter

A protocol for improving fabrication yield of thin SU-8 microcantilevers for use in an aptasensor

Y Lim, A Kouzani, A Kaynak, X Dai, G Littlefair, W Duan

(2015), Vol. 21, pp. 371-380, Microsystem technologies, Berlin, Germany, C1

journal article

Epigallocatechin-3-gallate induces the apoptosis of hepatocellular carcinoma LM6 cells but not non-cancerous liver cells.

Y Zhang, W Duan, L Owusu, D Wu, Y Xin

(2015), Vol. 35, pp. 117-124, International Journal of Molecular Medicine, Athens, Greece, C1

journal article

Graphene quantum dots induce apoptosis, autophagy, and inflammatory response via p38 mitogen-activated protein kinase and nuclear factor-?B mediated signaling pathways in activated THP-1 macrophages.

Y Qin, Z Zhou, S Pan, Z He, X Zhang, J Qiu, W Duan, T Yang, S Zhou

(2015), Vol. 327, pp. 62-76, Toxicology, Ireland, C1

journal article

Nucleic acid aptamer-guided cancer therapeutics and diagnostics: the next generation of cancer medicine

D Xiang, S Shigdar, G Qiao, T Wang, A Kouzani, S Zhou, L Kong, Y Li, C Pu, W Duan

(2015), Vol. 5, pp. 23-42, Theranostics, Wyoming, N.S.W., C1

journal article

Aptamer-mediated cancer gene therapy.

D Xiang, S Shigdar, G Qiao, S Zhou, Y Li, M Wei, L Qiao, H Shamaileh, Y Zhu, C Zheng, C Pu, W Duan

(2015), Vol. 15, pp. 109-119, Current Gene Therapy, Bussum, Netherlands, C1

journal article

Fabrication of high specificity hollow mesoporous silica nanoparticles assisted by Eudragit for targeted drug delivery.

X She, L Chen, L Velleman, C Li, H Zhu, C He, T Wang, S Shigdar, W Duan, L Kong

(2015), Vol. 445, pp. 151-160, Journal of Colloid and Interface Science, United States, C1

journal article

Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells.

Y Ding, Z Zhou, C Ha, X Zhang, S Pan, Z He, J Edelman, D Wang, Y Yang, X Zhang, W Duan, T Yang, J Qiu, S Zhou

(2015), Vol. 9, pp. 425-464, Drug Design, Development and Therapy, New Zealand, C1

journal article

The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells

J Li, Y Yang, Q Liu, Z Zhou, S Pan, Z He, X Zhang, T Yang, S Pan, W Duan, S He, X Chen, J Qiu, S Zhou

(2015), Vol. 9, pp. 1027-1062, Drug design, development and therapy, Macclesfield, Eng., C1

journal article

Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells

Y Wang, Y Yang, R Zhao, S Pan, H Zhe, Z He, W Duan, X Zhang, T Yang, J Qiu, S Zhou

(2015), Vol. 9, pp. 993-1026, Drug design, development and therapy, Auckland, New Zealand, C1

journal article

Clinical association between pharmacogenomics and adverse drug reactions

Z Zhou, X Chen, K Sneed, Y Yang, X Zhang, Z He, K Chow, T Yang, W Duan, S Zhou

(2015), Vol. 75, pp. 589-631, Drugs, Basel, Switzerland, C1

journal article

Sch9 regulates intracellular protein ubiquitination by controlling stress responses

B Qie, Z Lyu, L Lyu, J Liu, X Gao, Y Liu, W Duan, N Zhang, L Du, K Liu

(2015), Vol. 5, pp. 290-300, Redox biology, Amsterdam, The Netherlands, C1

journal article

Chansu inhibits the expression of cortactin in colon cancer cell lines in vitro and in vivo

C Li, S Hashimi, S Cao, J Qi, D Good, W Duan, M Wei

(2015), Vol. 15, pp. 1-8, BMC complementary and alternative medicine, London, Eng., C1

journal article

Clinical pharmacology of dipeptidyl peptidase 4 inhibitors indicated for the treatment of type 2 diabetes mellitus

X Chen, Z He, Z Zhou, T Yang, X Zhang, Y Yang, W Duan, S Zhou

(2015), Vol. 42, pp. 999-1024, Clinical and experimental pharmacology and physiology, London, Eng., C1

journal article

Cisplatin-induced formation of biocompatible and biodegradable polypeptide-based vesicles for targeted anticancer drug delivery

S Shirbin, K Ladewig, Q Fu, M Klimak, X Zhang, W Duan, G Qiao

(2015), Vol. 16, pp. 2463-2474, Biomacromolecules, Washington, D.C., C1

journal article

The control of epidermal growth factor grafted on mesoporous silica nanoparticles for targeted delivery

X She, L Chen, L Velleman, C Li, C He, J Denman, T Wang, S Shigdar, W Duan, L Kong

(2015), Vol. 3, pp. 6094-6104, Journal of materials chemistry B, Cambridge, Eng., C1

journal article

Superior performance of aptamer in tumor penetration over antibody : implication of aptamer-based theranostics in solid tumors

D Xiang, C Zheng, S Zhou, S Qiao, P Tran, C Pu, Y Li, L Kong, A Kouzani, J Lin, K Liu, L Li, S Shigdar, W Duan

(2015), Vol. 5, pp. 1083-1097, Theranostics, Sydney, N.S.W., C1

journal article

An update on the clinical pharmacology of the dipeptidyl peptidase 4 inhibitor alogliptin used for the treatment of type 2 diabetes mellitus.

X Chen, Z He, Z Zhou, T Yang, X Zhang, Y Yang, W Duan, S Zhou

(2015), Vol. 42, pp. 1225-1238, Clinical and experimental pharmacology and physiology, London, Eng., C1

journal article

Overcoming acquired drug resistance in colorectal cancer cells by targeted delivery of 5-FU with EGF grafted hollow mesoporous silica nanoparticles

L Chen, X She, T Wang, L He, S Shigdar, W Duan, L Kong

(2015), Vol. 7, pp. 14080-14092, Nanoscale, Cambridge, Eng., C1

journal article

Controllable drug uptake and nongenomic response through estrogen-anchored cyclodextrin drug complex

J Yin, S Shumyak, C Burgess, Z Zhou, Z He, X Zhang, S Pan, T Yang, W Duan, J Qiu, S Zhou

(2015), Vol. 10, pp. 4717-4730, International journal of nanomedicine, Auckland, N. Z., C1

journal article

Novel targeting of PEGylated liposomes for codelivery of TGF-?1 siRNA and four antitubercular drugs to human macrophages for the treatment of mycobacterial infection: a quantitative proteomic study

N Niu, J Yin, Y Yang, Z Wang, Z Zhou, Z He, X Chen, X Zhang, W Duan, T Yang, S Zhou

(2015), Vol. 9, pp. 4441-4470, Drug design, development and therapy, Macclesfield, Eng., C1

journal article

Cancer stem cell targeted therapy: progress amid controversies

T Wang, S Shigdar, M Gantier,, Y Hou,, L Wang,, Y Li,, H Shamaileh,, W Yin, S Zhou,, X Zhao,, W Duan

(2015), Vol. 6, pp. 44191-44206, Oncotarget, Albany, N.Y., C1

journal article

EpCAM aptamer-mediated survivin silencing sensitized cancer stem cells to doxorubicin in a breast cancer model

T Wang, M Gantier, D Xiang, A Bean, M Bruce, S Zhou, M Khasraw, A Ward, L Wang, M Wei, H AlShamaileh, L Chen, X She, J Lin, L Kong, S Shigdar, W Duan

(2015), Vol. 5, pp. 1456-1472, Theranostics, Wyoming, N.S.W., C1

journal article
2014

Inflammation and cancer stem cells

S Shigdar, Y Li, S Bhattacharya, M O'Connor, C Pu, J Lin, T Wang, D Xiang, L Kong, M Wei, Y Zhu, S Zhou, W Duan

(2014), Vol. 345, pp. 271-278, Cancer Letters, C1

journal article

A surface-stress-based microcantilever aptasensor

Y Lim, A Kouzani, W Duan, X Dai, A Kaynak, D Mair

(2014), Vol. 8, pp. 15-24, IEEE Transactions on Biomedical Circuits and Systems, C1

journal article

Improved efficacy and reduced toxicity of doxorubicin encapsulated in sulfatide-containing nanoliposome in a glioma model

J Lin, S Shigdar, D Fang, D Xiang, M Wei, A Danks, L Kong, L Li, L Qiao, W Duan

(2014), Vol. 9, pp. 1-13, Plos One, San Francisco, CA, C1

journal article

Multifunctional nanoparticle-EpCAM aptamer bioconjugates: a paradigm for targeted drug delivery and imaging in cancer therapy

M Das, W Duan, S Sahoo

(2014), pp. 1-11, Nanomedicine : nanotechnology, biology and medicine, Amsterdam, The Netherlands, C1

journal article

Synergistic effects of IAP inhibitor LCL161 and paclitaxel on hepatocellular carcinoma cells.

A Tian, G Wilson, S Lie, G Wu, Z Hu, L Hebbard, W Duan, J George, L Qiao

(2014), Vol. 351, pp. 232-241, Cancer Letters, Ireland, C1

journal article

Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K/Akt/mTOR pathway in human non-small cell lung cancer cells

Y Li, S He, Z He, M Li, Y Yang, J Pang, X Zhang, K Chow, Q Zhou, W Duan, Z Zhou, T Yang, G Huang, A Liu, J Qiu, J Liu, S Zhou

(2014), Vol. 344, pp. 239-259, Cancer Letters, Shannon, County Clare, Ireland, C1

journal article

Cancer stem cells: a contentious hypothesis now moving forward

M O'Connor, D Xiang, S Shigdar, J Macdonald, Y Li, T Wang, C Pu, Z Wang, L Qiao, W Duan

(2014), Vol. 344, pp. 180-187, Cancer letters, Shannon, Ireland, C1

journal article

Cancer stem cells in prostate cancer chemoresistance

J Ni, P Cozzi, J Hao, W Duan, P Graham, J Kearsley, Y Li

(2014), Vol. 14, pp. 225-240, Current cancer drug targets, Bussum, Netherlands, C1

journal article

CD44 variant 6 is associated with prostate cancer metastasis and chemo-/radioresistance

J Ni, P Cozzi, J Hao, J Beretov, L Chang, W Duan, S Shigdar, W Delprado, P Graham, J Bucci, J Kearsley, Y Li

(2014), Vol. 74, pp. 602-617, Prostate, Hoboken, NJ, C1

journal article

Prediction of the likelihood of drug interactions with kinase inhibitors based on in vitro and computational studies

Z-X Wang, J Sun, C Howell, Q-Y Zhou, Z-X He, T Yang, H Chew, W Duan, Z-W Zhou, J Kanwar, S-F Zhou

(2014), Vol. 28, pp. 551-582, Fundamental and clinical pharmacology, Chichester, England, C1

journal article

Smoothened activates breast cancer stem-like cell and promotes tumorigenesis and metastasis of breast cancer

L Wang, W Duan, L Kang, J Mao, X Yu, S Fan, L Li, Y Tao

(2014), Vol. 68, pp. 1099-1104, Biomedicine & pharmacotherapy, Amsterdam, The Netherlands, C1

journal article

Theoretical modeling and experimental validation of surface stress in thrombin aptasensor

Y Lim, A Kouzani, A Kaynak, X Dai, G Littlefair, W Duan

(2014), Vol. 13, pp. 384-391, IEEE Transactions on Nanobioscience, C1

journal article

Epithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells

L Li, D Xiang, S Shigdar, W Yang, Q Li, J Lin, K Liu, W Duan

(2014), Vol. 9, pp. 1083-1096, International journal of nanomedicine, Macclesfield, England, C1

journal article

Exposure to 1800 MHz radiofrequency radiation impairs neurite outgrowth of embryonic neural stem cells

C Chen, Q Ma, C Liu, P Deng, G Zhu, L Zhang, M He, Y Lu, W Duan, L Pei, M Li, Z Yu, Z Zhou

(2014), Vol. 4, pp. 1-10, Scientific reports, London, Eng., C1-1

journal article

?-mangostin inhibits hypoxia-driven ROS-induced PSC activation and pancreatic cancer cell invasion

J Lei, X Huo, W Duan, Q Xu, R Li, J Ma, X Li, L Han, W Li, H Sun, E Wu, Q Ma

(2014), Vol. 347, pp. 129-138, Cancer letters, Amsterdam, The Netherlands, C1-1

journal article

Design and evaluation of a microcantilever aptasensor

Y Lim, A Kouzani, W Duan, X Dai, A Kaynak, D Mair

(2014), pp. 221-224, ISCAS 2014 : Proceedings of the 2014 IEEE International Symposium on Circuits and Systems, Melbourne, Victoria, E1

conference
2013

Localized surface plasmon resonance: nano-sinusoid arrays

D Mortazavi, A Kouzani, L Matekovits, W Duan

(2013), Vol. 27, pp. 638-648, Journal of electromagnetic waves and applications, London, Eng., C1

journal article

Cloning of the crustacean hyperglycemic hormone and evidence for molt-inhibiting hormone within the central nervous system of the blue crab Portunus pelagicus

M Stewart, P Stewart, M Sroyraya, N Soonklang, S Cummins, P Hanna, W Duan, P Sobhon

(2013), Vol. 164, pp. 276-290, Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology, C1

journal article

RNA aptamers targeting cancer stem cell marker CD133

S Shigdar, L Qiao, S Zhou, D Xiang, T Wang, Y Li, L Lim, L Kong, L Li, W Duan

(2013), Vol. 330, pp. 84-95, Cancer Letters, C1

journal article

The use of sensitive chemical antibodies for diagnosis: detection of low levels of Epcam in breast cancer

S Shigdar, C Qian, L Lv, C Pu, Y Li, L Li, M Marappan, J Lin, L Wang, W Duan

(2013), Vol. 8, pp. 1-8, PLoS One, San Diego, United States, C1

journal article

Epithelial cell adhesion molecule (EpCAM) is associated with prostate cancer metastasis and chemo/radioresistance via the PI3K/Akt/mTOR signaling pathway

J Ni, P Cozzi, J Hao, J Beretov, L Chang, W Duan, S Shigdar, W Delprado, P Graham, J Bucci, J Kearsley, Y Li

(2013), Vol. 45, pp. 2736-2748, International Journal of Biochemistry and Cell Biology, C1

journal article

Inhibition of A/Human/Hubei/3/2005 (H3N2) influenza virus infection by silver nanoparticles in vitro and in vivo

D Xiang, D Xiang, Z Yang, Z Yang, W Duan, W Duan, X Li, X Li, J Yin, J Yin, S Shigdar, S Shigdar, M O'Connor, M O'Connor, M Marappan, M Marappan, X Zhao, X Zhao, Y Miao, Y Miao, B Xiang, B Xiang, C Zheng, C Zheng

(2013), Vol. 8, pp. 4103-4114, International Journal of Nanomedicine, Macclesfield, UK, C1

journal article

Aptamers as theranostic agents: modifications, serum stability and functionalisation

S Shigdar, J Macdonald, M O'Connor, T Wang, D Xiang, H Al.Shamaileh, L Qiao, M Wei, S Zhou, Y Zhu, L Kong, S Bhattacharya, C Li, W Duan

(2013), Vol. 13, pp. 13624-13637, Sensors, Basel, Switzerland, C1

journal article

Selection of DNA aptamers against epithelial cell adhesion molecule for cancer cell imaging and circulating tumor cell capture

Y Song, Z Zhu, Y An, W Zhang, H Zhang, D Liu, C Yu, W Duan, C Yang

(2013), Vol. 85, pp. 4141-4149, Analytical Chemistry, C1

journal article

Synthesis and Biological Evaluation of Novel Folic Acid Receptor-Targeted, ?-Cyclodextrin-Based Drug Complexes for Cancer Treatment

J Yin, S Sharma, S Shumyak, Z Wang, Z Zhou, Y Zhang, P Guo, C Li, J Kanwar, T Yang, S Mohapatra, W Liu, W Duan, J Wang, Q Li, X Zhang, J Tan, L Jia, J Liang, M Wei, X Li, S Zhou

(2013), Vol. 8, PLoS ONE, C1

journal article

Peptide-Fluorescent Bacteria Complex as Luminescent Reagents for Cancer Diagnosis

B Dong, A Wang, L Yuan, L Chen, K Pu, W Duan, X Yan, Y Zhu

(2013), Vol. 8, PLoS ONE, C1

journal article

Efficacy of using cancer stem cell markers in isolating and characterizing liver cancer stem cells

G Wilson, Z Hu, W Duan, A Tian, X Wang, D McLeod, V Lam, J George, L Qiao

(2013), Vol. 22, pp. 2655-2664, Stem Cells and Development, C1

journal article

Anti-metastatic and differential effects on protein expression of epigallocatechin-3-gallate in HCCLM6 hepatocellular carcinoma cells

Y Zhang, L Owusu, W Duan, T Jiang, S Zang, A Ahmed, Y Xin

(2013), Vol. 32, pp. 959-964, International Journal of Molecular Medicine, C1

journal article

Tumoricidal effects of the JAK inhibitor Ruxolitinib (INC424) on hepatocellular carcinoma in vitro

G Wilson, A Tian, L Hebbard, W Duan, J George, X Li, L Qiao

(2013), Vol. 341, pp. 224-230, Cancer Letters, C1

journal article

Multifunctional and multitargeted nanoparticles for drug delivery to overcome barriers of drug resistance in human cancers

S Dawar, N Singh, R Kanwar, R Kennedy, R Veedu, S Zhou, S Krishnakumar, S Hazra, S Sasidharan, W Duan, J Kanwar

(2013), Vol. 18, pp. 1292-1300, Drug Discovery Today, C1

journal article

The mechanisms of Chansu in inducing efficient apoptosis in colon cancer cells

C Li, S Hashimi, S Cao, A Mellick, W Duan, D Good, M Wei

(2013), Vol. 2013, Evidence-based Complementary and Alternative Medicine, C1

journal article

Role of surface charge and oxidative stress in cytotoxicity and genotoxicity of graphene oxide towards human lung fibroblast cells

A Wang, K Pu, B Dong, Y Liu, L Zhang, Z Zhang, Duan Wei, Y Zhu

(2013), Vol. 33, pp. 1156-1164, Journal of applied toxicology, Bognor Regis, England, C1-1

journal article
2012

Role of Multidrug Resistance Associated Proteins in drug Development

S Zhou, J Liu, M Wei, W Duan

(2012), pp. 3-35, Multidrug Resistance A Global Concern, B1

book chapter

Aptamers and nanomedicine

S Shigdar, A Smith, W Duan

(2012), pp. 275-296, Nanotechnology in Health Care, B1-1

book chapter

Developing LSPR design guidelines

D Mortazavi, A Kouzani, A Kaynak, W Duan

(2012), Vol. 126, pp. 203-235, Progress in Electromagnetics Research, C1

journal article

Cancer stem cell targeting: The next generation of cancer therapy and molecular imaging

S Shigdar, J Lin, Y Li, C Yang, M Wei, Y Zhu, H Liu, W Duan

(2012), Vol. 3, pp. 227-244, Therapeutic Delivery, C1

journal article

Clostridial spores for cancer therapy: Targeting solid tumour microenvironment

B Umer, D Good, J Ann, W Duan, M Wei

(2012), Vol. 2012, Journal of Toxicology, C1

journal article

Enhanced Antitumor Efficacy and Reduced Systemic Toxicity of Sulfatide-Containing Nanoliposomal Doxorubicin in a Xenograft Model of Colorectal Cancer

J Lin, Y Yu, S Shigdar, D Fang, J Du, M Wei, A Danks, K Liu, W Duan

(2012), Vol. 7, PLoS ONE, C1-1

journal article

Apoptosis and microRNA aberrations in cancer

C Li, S Hashimi, D Good, S Cao, W Duan, P Plummer, A Mellick, M Wei

(2012), Vol. 39, pp. 739-746, Clinical and Experimental Pharmacology and Physiology, C1

journal article

Role of the EpCAM (CD326) in prostate cancer metastasis and progression

J Ni, P Cozzi, W Duan, S Shigdar, P Graham, K John, Y Li

(2012), Vol. 31, pp. 779-791, Cancer and Metastasis Reviews, C1

journal article
2011

Cancer gene therapy : developments and future perspectives

D Good, W Duan, J Anne, M Wei

(2011), pp. 299-314, Gene therapy - Developments and Future Perspectives, Rijeka, Croatia, B1

book chapter

Elevated levels of triglyceride and triglyceride-rich lipoprotein triglyceride induced by a high-carbohydrate diet is associated with polymorphisms of APOA5-1131T>C and APOC3-482C>T in Chinese healthy young adults

J Lin, D Fang, J Du, S Shigdar, L Xiao, X Zhou, W Duan

(2011), Vol. 58, pp. 150-157, Annals of Nutrition and Metabolism, C1

journal article

Associations of the SREBP-1c gene polymorphism with gender-specific changes in serum lipids induced by a high-carbohydrate diet in healthy chinese youth

Z Zhang, R Gong, J Du, L Xiao, W Duan, X Zhou, D Fang

(2011), Vol. 36, pp. 226-232, Applied Physiology, Nutrition and Metabolism, C1

journal article

Clinical applications of aptamers and nucleic acid therapeutics in haematological malignancies

S Shigdar, A Ward, A De, C Yang, M Wei, W Duan

(2011), Vol. 155, pp. 3-13, British Journal of Haematology, C1

journal article

Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study

Y Liu, S Mo, H Bi, B Hu, C Li, Y Wang, L Huang, M Huang, W Duan, J Liu, M Wei, S Zhou

(2011), Vol. 41, pp. 259-280, Xenobiotica, C1

journal article

Effects of lipoprotein lipase gene variations, a high-carbohydrate low-fat diet, and gender on serum lipid profiles in healthy Chinese Han youth

X Huang, R Gong, J Lin, R Li, L Xiao, W Duan, D Fang

(2011), Vol. 5, pp. 198-204, BioScience Trends, C1

journal article

RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule

S Shigdar, J Lin, Y Yu, M Pastuovic, M Wei, W Duan

(2011), Vol. 102, pp. 991-998, Cancer Science, C1-1

journal article

A micromechanical biosensor with interdigitated capacitor readout

Y Lim, A Kouzani, A Kaynak, R Al-Ameri, W Duan

(2011), pp. 42-46, 2011 IEEE/ICME International Conference on Complex Medical Engineering, CME 2011, E1

conference

Nano-plasmonic biosensors: A review

D Mortazavi, A Kouzani, A Kaynak, W Duan

(2011), pp. 31-36, 2011 IEEE/ICME International Conference on Complex Medical Engineering, CME 2011, E1

conference
2010

Aptasensors: A review

Y Lim, A Kouzani, W Duan

(2010), Vol. 6, pp. 93-105, Journal of Biomedical Nanotechnology, C1

journal article

Lab-on-a-chip: A component view

Y Lim, A Kouzani, W Duan

(2010), Vol. 16, pp. 1995-2015, Microsystem Technologies, C1

journal article

Spermatogenesis in the blue swimming crab, Portunus pelagicus, and evidence for histones in mature sperm nuclei

M Stewart, P Stewart, N Soonklang, V Linthong, P Hanna, W Duan, P Sobhon

(2010), Vol. 42, pp. 137-150, Tissue and Cell, C1

journal article

Disposition pathways and pharmacokinetics of herbal medicines in humans

S He, C Li, J Liu, E Chan, W Duan, S Zhou

(2010), Vol. 17, pp. 4072-4113, Current Medicinal Chemistry, C1

journal article

Aptamer Therapeutics: The 21st Century`s Magic Bullet of Nanomedicine

Sarah Shigdar, Jasmina Luczo, Ming Wei, Richard Bell, Andrew Danks, Ke Liu, Wei Duan

(2010), Vol. 1, pp. 118-124, The Open Conference Proceedings Journal, C1-1

journal article

TaqIB polymorphism in the CETP gene modulates the impact of HC/LF diet on the HDL profile in healthy Chinese young adults

J Du, D Fang, J Lin, L Xiao, X Zhou, S Shigdar, W Duan

(2010), Vol. 21, pp. 1114-1119, Journal of nutritional biochemistry, New York, N.Y., C1-1

journal article

Effects of design parameters on sensitivity of microcantilever biosensors

Y Lim, A Kouzani, W Duan, A Kaynak

(2010), pp. 177-181, 2010 IEEE/ICME International Conference on Complex Medical Engineering, CME2010, E1

conference

Design and construction of a micropump for drug delivery applications

A Kouzani, M Ivankovic, M Fielding, A Kaynak, C Yang, W Duan, E Hu

(2010), pp. 182-187, IEEE/ICME 2010 : Proceedings of the 2010 International Conference on Complex Medical Engineering, Gold Coast, Australia, E1

conference
2009

Aptasensors design considerations

Y Lim, A Kouzani, W Duan

(2009), pp. 118-127, Computational intelligence and intelligent systems, Berlin, Germany, B1

book chapter

GSK3? modulates PACAP-induced neuritogenesis in PC12 cells by acting downstream of Rap1 in a caveolae-dependent manner

W Zhang, A Smith, J Liu, N Cheung, S Zhou, K Liu, Q Li, W Duan

(2009), Vol. 21, pp. 237-245, Cellular Signalling, C1

journal article

Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6

S Mo, Y Liu, W Duan, M Wei, J Kanwar, S Zhou

(2009), Vol. 10, pp. 730-753, Current Drug Metabolism, C1

journal article

Insights into the structure, function, and regulation of human cytochrome P450 1A2

S Zhou, L Yang, M Wei, W Duan, E Chan

(2009), Vol. 10, pp. 713-729, Current Drug Metabolism, C1-1

journal article
2008

Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development

S Zhou, L Wang, Y Di, C Xue, W Duan, C Li, Y Li

(2008), Vol. 15, pp. 1981-2039, Current Medicinal Chemistry, C1

journal article

The C-terminus of PRK2/PKN? is required for optimal activation by RhoA in a GTP-dependent manner

W Lim, X Chen, J Liu, B Tan, S Zhou, A Smith, N Lees, L Hou, F Gu, X Yu, Y Du, D Smith, C Verma, K Liu, W Duan

(2008), Vol. 479, pp. 170-178, Archives of Biochemistry and Biophysics, C1

journal article

Clinical pharmacogenetics and potential application in personalized medicine

S Zhou, Y Di, E Chan, Y Du, V Chow, C Xue, X Lai, J Wang, C Li, M Tian, W Duan

(2008), Vol. 9, pp. 738-784, Current Drug Metabolism, C1

journal article

Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc

D Xu, J Dwyer, H Li, W Duan, J Liu

(2008), Vol. 283, pp. 23567-23580, Journal of Biological Chemistry, C1

journal article

Protein kinase C isozymes as potential therapeutic targets in immune disorders

M Lee, W Duan, S Tan

(2008), Vol. 12, pp. 535-552, Expert Opinion on Therapeutic Targets, C1

journal article
2007

Emerging host cell targets for hepatitis C therapy

Y He, W Duan, S Tan

(2007), Vol. 12, pp. 209-217, Drug Discovery Today, C1

journal article

Sulfatide-tenascin interaction mediates binding to the extracellular matrix and endocytic uptake of liposomes in glioma cells

K Shao, Q Hou, M Go, W Duan, N Cheung, S Feng, K Wong, A Yoram, W Zhang, Z Huang, Q Li

(2007), Vol. 64, pp. 506-515, Cellular and molecular life sciences, Basel, Switzerland, C1

journal article

Role of P-Glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge

X Yu, S Lin, Z Zhou, X Chen, J Liang, P Liu, W Duan, B Chowbay, J Wen, C Li, S Zhou

(2007), Vol. 8, pp. 325-340, Current Drug Metabolism, C1

journal article

Role of p-glycoprotein in limiting the brain penetration of glabridin, an active isoflavan from the root of Glycyrrhiza glabra

X Yu, S Lin, Z Zhou, X Chen, J Liang, X Yu, B Chowbay, J Wen, W Duan, E Chan, X Li, J Cao, C Li, C Xue, S Zhou

(2007), Vol. 24, pp. 1668-1690, Pharmaceutical Research, C1

journal article

Role of ATP-binding cassette drug transporters in the intestinal absorption of tanshinone IIB, one of the major active diterpenoids from the root of Salvia miltiorrhiza

X Yu, Z Zhou, S Lin, X Chen, X Yu, J Liang, W Duan, J Wen, X Li, S Zhou

(2007), Vol. 37, pp. 375-415, Xenobiotica, C1

journal article

Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: Application to cellular metabolism and accumulation studies

Z Hu, X Yang, X Chen, E Chan, W Duan, S Zhou

(2007), Vol. 850, pp. 575-580, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, C1

journal article

Histological studies of the ovaries of two tropical portunid crabs, portunus pelagicus (l.) and scylla serrata (f.)

M Stewart, N Soonklang, P Stewart, P Hanna, C Wanichanon, A Parratt, W Duan, P Sobhon

(2007), Vol. 50, pp. 85-97, Invertebrate Reproduction and Development, C1

journal article

Pituitary adenylate cyclase-activating polypeptide induces translocation of its G-protein-coupled receptor into caveolin-enriched membrane microdomains, leading to enhanced cyclic AMP generation and neurite outgrowth in PC12 cells

W Zhang, W Duan, N Cheung, Z Huang, K Shao, Q Li

(2007), Vol. 103, pp. 1157-1167, Journal of Neurochemistry, C1

journal article

Tanshinone IIB, a primary active constituent from Salvia miltiorrhza, exhibits neuro-protective activity in experimentally stroked rats

X Yu, S Lin, Z Zhou, X Chen, J Liang, W Duan, X Yu, J Wen, B Chowbay, C Li, F Sheu, E Chan, S Zhou

(2007), Vol. 417, pp. 261-265, Neuroscience Letters, C1

journal article

Design of new oxazaphosphorine anticancer drugs

J Liang, M Huang, W Duan, X Yu, S Zhou

(2007), Vol. 13, pp. 963-978, Current Pharmaceutical Design, C1

journal article

A mechanistic study on altered pharmacokinetics of irinotecan by St. John's Wort

Z Hu, X Yang, X Chen, J Cao, E Chan, W Duan, M Huang, X Yu, J Wen, S Zhou

(2007), Vol. 8, pp. 157-171, Current Drug Metabolism, C1

journal article

Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier

X Yu, S Lin, X Chen, Z Zhou, J Liang, W Duan, B Chowbay, J Wen, E Chan, J Cao, C Li, S Zhou

(2007), Vol. 8, pp. 365-377, Current Drug Metabolism, C1

journal article

Role of P-glycoprotein in the intestinal absorption of glabridin, an active flavonoid from the root of Glycyrrhiza glabra

J Cao, X Chen, J Liang, X-Q Yu, A-L Xu, E Chan, W Duan, M Huang, J-Y Wen, X-Y Yu, X-T Li, F-S Sheu, S-F Zhou

(2007), Vol. 35, pp. 539-553, Drug metabolism and disposition, Bethesda, Md., C1-1

journal article
2006

The last 10 amino acid residues beyond the hydrophobic motif are critical for the catalytic competence and function of protein kinase C?

S Sui, Y Zhu, D Smith, C Verma, G Wee, J Bee, T Qiu, S Nam, M Cai, Y Zhu, S Zhou, S Tan, W Duan

(2006), Vol. 281, pp. 30768-30781, Journal of Biological Chemistry, C1

journal article

The very C-terminus of protein kinase C? is critical for the full catalytic competence but its hydrophobic motif is dispensable for the interaction with 3-phosphoinositide-dependent kinase-1 B

Y Zhu, D Smith, C Verma, W Lim, B Tan, J Armstrong, S Zhou, E Chan, S Tan, Y Zhu, N Cheung, W Duan

(2006), Vol. 18, pp. 807-818, Cellular Signalling, C1-1

journal article

Analysis of cardioprotective effects using purified Salvia miltiorrhiza extract on isolated rat hearts

N Piek, C Jian, H Shan, L Ning, J Zhong, T On, W Duan, Z Yi

(2006), Vol. 101, pp. 245-249, Journal of Pharmacological Sciences, C1-1

journal article

Drug-herb interactions: Eliminating toxicity with hard drug design

X Yang, Z Hu, W Duan, Y Zhu, S Zhou

(2006), Vol. 12, pp. 4649-4664, Current Pharmaceutical Design, C1-1

journal article

St. John's wort attenuates irinotecan-induced diarrhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosis

Z Hu, X Yang, S Chan, A Xu, W Duan, Y Zhu, F Sheu, U Boelsterli, E Chan, Q Zhang, J Wang, P Ee, H Koh, M Huang, S Zhou

(2006), Vol. 216, pp. 225-237, Toxicology and Applied Pharmacology, C1-1

journal article

Relationship of glutathione S-transferase genotypes with side-effects of pulsed cyclophosphamide therapy in patients with systemic lupus erythematosus

S Zhong, M Huang, X Yang, L Liang, Y Wang, M Romkes, W Duan, E Chan, S Zhou

(2006), Vol. 62, pp. 457-472, British Journal of Clinical Pharmacology, C1-1

journal article

Intracellular drug delivery by sulfatide-mediated liposomes to gliomas

K Shao, Q Hou, W Duan, M Go, K Wong, Q Li

(2006), Vol. 115, pp. 150-157, Journal of Controlled Release, C1-1

journal article

Genetic polymorphisms of cytochrome P450 2B6 gene in Han Chinese

S Guan, M Huang, E Chan, X Chen, W Duan, S Zhou

(2006), Vol. 29, pp. 14-21, European Journal of Pharmaceutical Sciences, C1-1

journal article

Pharmacokinetics of recombinant human endostatin in rats

X Yang, Z Hu, E Chan, W Duan, S Zhou

(2006), Vol. 7, pp. 565-576, Current Drug Metabolism, C1-1

journal article

A mechanistic study on reduced toxicity of irinotecan by coadministered thalidomide, a tumor necrosis factor-? inhibitor

X Yang, Z Hu, A Xu, W Duan, Y Zhu, M Huang, F Sheu, Q Zhang, J Bian, E Chan, X Li, J Wang, S Zhou

(2006), Vol. 319, pp. 82-104, Journal of Pharmacology and Experimental Therapeutics, C1-1

journal article

Small interfering RNA-mediated silencing of cytochrome P450 3A4 gene

J Chen, X Yang, M Huang, Z Hu, M He, W Duan, E Chan, F Sheu, X Chen, S Zhou

(2006), Vol. 34, pp. 1650-1657, Drug Metabolism and Disposition, C1-1

journal article

A mechanistic study of the intestinal absorption of cryptotanshinone, the major active constituent of Salvia miltiorrhiza

J Zhang, M Huang, S Guan, H Bi, Y Pan, W Duan, Y Sui, X Chen, Y Hong, J Bian, H Yang, S Zhou

(2006), Vol. 317, pp. 1285-1294, Journal of Pharmacology and Experimental Therapeutics, C1-1

journal article

Early induction of chalpains in rotenone-mediated neuronal apoptosis

M Chen, Y Yap, M Choy, C Koh, S Seet, W Duan, M Whiteman, N Cheung

(2006), Vol. 397, pp. 69-73, Neuroscience letters, Limerick, Ireland, C1-1

journal article

Nitric oxide protects against mitochondrial permeabilization induced by glutathione depletion: Role of S-nitrosylation?

M Whiteman, Y Chua, D Zhang, W Duan, Y Liou, J Armstrong

(2006), Vol. 339, pp. 255-262, Biochemical and Biophysical Research Communications, C1-1

journal article

A study of the effects of flux density and frequency of pulsed electromagnetic field on neurite outgrowth in PC12 cells

Y Zhang, J Ding, W Duan

(2006), Vol. 32, pp. 1-9, JOURNAL OF BIOLOGICAL PHYSICS, C1-1

journal article

Monitoring of immune responses to a herbal immuno-modulator in patients with advanced colorectal cancer

X Chen, Z Hu, X Yang, M Huang, Y Gao, W Tang, S Chan, X Dai, J Ye, P Ho, W Duan, H Yang, Y Zhu, S Zhou

(2006), Vol. 6, pp. 499-508, International Immunopharmacology, C1-1

journal article

Topotecan is a substrate for multidrug resistance associated protein 4

Q Tian, J Zhang, S Chan, T Tan, W Duan, M Huang, Y Zhu, E Chan, Q Yu, Y Nie, P Ho, Q Li, K Ng, H Yang, H Wei, J Bian, S Zhu

(2006), Vol. 7, pp. 105-118, Current Drug Metabolism, C1-1

journal article

The very C-terminus of PRK1/PKN is essential for its activation by RhoA and downstream signaling

W Lim, B Tan, Y Zhu, S Zhou, J Armstrong, Q Li, Q Dong, E Chan, D Smith, C Verma, S Tan, W Duan

(2006), Vol. 18, pp. 1473-1481, Cellular Signalling, C1-1

journal article

Use of in vitro critical inhibitory concentration, a novel approach to predict in vivo synergistic bactericidal effect of combined amikacin and piperacillin against Pseudomonas aeruginosa in a systemic rat infection model

E Chan, S Zhou, S Srikumar, W Duan

(2006), Vol. 23, pp. 729-741, Pharmaceutical Research, C1-1

journal article

A comparison study of cerebral protection using Ginkgo biloba extract and Losartan on stroked rats

K Loh, L Low, W Wong, S Zhou, S Huang, R De Silva, W Duan, W Chou, Y Zhu

(2006), Vol. 398, pp. 28-33, Neuroscience Letters, C1-1

journal article

U18666A-mediated apoptosis in cultured murine cortical neurons: Role of caspases, calpains and kinases

C Koh, R Qi, D Qu, A Melendez, J Manikandan, B Bay, W Duan, N Cheung

(2006), Vol. 18, pp. 1572-1583, Cellular Signalling, C1-1

journal article

Pharmacokinetic mechanisms for reduced toxicity of irinotecan by coadministered thalidomide

X Yang, Z Hu, S Chan, W Duan, P Ho, U Boelsterli, K Ng, E Chan, J Bian, Y Chen, M Huang, S Zhou

(2006), Vol. 7, pp. 431-454, Current Drug Metabolism, C1-1

journal article

Induction of propranolol metabolism by Ginkgo biloba extract EGb 761 in rats

L Zhao, M Huang, J Chen, P Ee, E Chan, W Duan, Y Guan, Y Hong, X Chen, S Zhou

(2006), Vol. 7, pp. 577-587, Current Drug Metabolism, C1-1

journal article

Relationship between genotype and enzyme activity of glutathione S-transferases M1 and P1 in Chinese

S Zhong, S Zhou, X Chen, S Chan, E Chan, K Ng, W Duan, M Huang

(2006), Vol. 28, pp. 77-85, European Journal of Pharmaceutical Sciences, C1-1

journal article
2005

Identification of an integral plasma membrane pool of protein kinase C in mammalian tissues and cells

Y Zhu, G Wee, J Bee, S Tian, W Duan

(2005), Vol. 17, pp. 1125-1136, Cellular Signalling, C1-1

journal article

The PKC alpha-D294G mutant found in pituitary and thyroid tumors fails to transduce extracellular signals

Y Zhu, Q Dong, B Tan, W Lim, S Zhou, W Duan

(2005), Vol. 65, pp. 4520-4524, CANCER RESEARCH, C1-1

journal article

Metabolism and transport of oxazaphosphorines and the clinical implications

J Zhang, Q Tian, Y Sui, C Shu, S Zhou, W Duan, Y Zhu

(2005), Vol. 37, pp. 611-703, Drug metabolism reviews, Abingdon, Eng., C1-1

journal article

Effects of purified herbal extract of Salvia miltiorrhiza on ischemic rat myocardium after acute myocardial infarction

J Sun, S Huang, B Tan, M Whiteman, Y Zhu, Y Wu, Y Ng, W Duan, Y Zhu

(2005), Vol. 76, pp. 2849-2860, Life Sciences, C1-1

journal article

The last five amino acid residues at the C-terminus of PRK1/PKN is essential for full lipid responsiveness

G Wee, Y Zhu, C Wang, J Bee, J Armstrong, T Dokland, H Yang, Y Zhu, S Tian, W Duan

(2005), Vol. 17, pp. 1084-1097, Cellular Signalling, C1-1

journal article

Prediction of herb-drug metabolic interactions: A simulation study

S Zhou, M Huang, A Xu, H Yang, W Duan, J Paxton

(2005), Vol. 19, pp. 464-471, Phytotherapy Research, C1-1

journal article

Simultaneous determination of the lactone and carboxylate forms of irinotecan (CPT-11) and its active metabolite SN-38 by high-performance liquid chromatography: Application to plasma pharmacokinetic studies in the rat

X Yang, Z Hu, Y Sui, B Goh, W Duan, E Chan, S Zhou

(2005), Vol. 821, pp. 221-228, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, C1-1

journal article

Molecular characterization of Osh6p, an oxysterol binding protein homolog in the yeast Saccharomyces cerevisiae

P Wang, W Duan, A Munn, H Yang

(2005), Vol. 272, pp. 4703-4715, FEBS journal, London, England, C1-1

journal article

Influence of pulsed electromagnetic field with different pulse duty cycles on neurite outgrowth in PC12 rat pheochromocytoma cells

Y Zhang, J Ding, W Duan, W Fan

(2005), Vol. 26, pp. 406-411, Bioelectromagnetics, New York, N.Y., C1-1

journal article

Human multidrug resistance associated protein 4 confers resistance to camptothecins

Q Tian, J Zhang, T Tan, E Chan, W Duan, Y Sui, U Boelsterli, P Ho, H Yang, J Bian, M Huang, Y Zhu, W Xiong, X Li, S Zhou

(2005), Vol. 22, pp. 1837-1853, Pharmaceutical Research, C1-1

journal article

Alteration of the pharmacokinetics of COL-3, a matrix metalloproteinase inhibitor, due to acute gastrointestinal toxicity of doxorubicin

J Li, S Zhou, H Huynh, W Duan, E Chan

(2005), Vol. 22, pp. 1954-1963, Pharmaceutical Research, C1-1

journal article

Antitumor activity and underlying mechanisms of ganopoly, the refined polysaccharides extracted from ganoderma lucidum, in mice

Y Gao, H Gao, E Chan, W Tang, A Xu, H Yang, M Huang, J Lan, X Li, W Duan, C Xu, S Zhou

(2005), Vol. 34, pp. 171-198, Immunological Investigations, C1-1

journal article

Insights into oxazaphosphorine resistance and possible approaches to its circumvention

J Zhang, Q Tian, S Chan, W Duan, S Zhou

(2005), Vol. 8, pp. 271-297, Drug Resistance Updates, C1-1

journal article

St. John's wort modulates the toxicities and pharmacokinetics of CPT-11 (Irinotecan) in rats

Z Hu, X Yang, P Ho, E Chan, Y Sui, C Xu, X Li, Y Zhu, W Duan, X Chen, M Huang, H Yang, S Zhou

(2005), Vol. 22, pp. 902-914, Pharmaceutical Research, C1-1

journal article

Determination of thalidomide by high performance liquid chromatography: Plasma pharmacokinetic studies in the rat

X Yang, Z Hu, Y Sui, P Ho, E Chan, W Duan, C Boon, S Zhou

(2005), Vol. 39, pp. 299-304, Journal of Pharmaceutical and Biomedical Analysis, C1-1

journal article

Herb-drug interactions: A literature review

Z Hu, X Yang, P Ho, Y Sui, P Heng, E Chan, W Duan, L Hwee, S Zhou

(2005), Vol. 65, pp. 1239-1282, Drugs, C1-1

journal article

Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs

S Zhou, S Chan, B Goh, E Chan, W Duan, M Huang, H McLeod

(2005), Vol. 44, pp. 279-304, Clinical Pharmacokinetics, C1-1

journal article

Drug bioactivation, covalent binding to target proteins and toxicity relevance

S Zhou, E Chan, W Duan, M Huang, Y Chen

(2005), Vol. 37, pp. 41-213, Drug Metabolism Reviews, C1-1

journal article

Inhaled p38a mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice

W Duan, J Chan, K McKay, J Crosby, H Choo, B Leung, J Karras, W Wong

(2005), Vol. 171, pp. 571-578, American journal of respiratory and critical care medicine, New York, N.Y., C1-1

journal article

Multidrug resistance proteins (MRPs) and implication in drug development

Q Tian, J Zhang, E Chan, W Duan, S Zhou

(2005), Vol. 64, pp. 1-18, Drug development research, New York, N.Y., C1-1

journal article

An anti-inflammatory role for a phosphoinositide 3-kinase inhibitor LY294002 in a mouse asthma model

W Duan, A Aguinaldo Datiles, B Leung, C Vlahos, W Wong

(2005), Vol. 5, pp. 495-502, International immunopharmacology, Amsterdam, The Netherlands, C1-1

journal article

The PKCa-D294G mutant found in pituitary and thyroid tumors fails to transduce extracellular signals

Y Zhu, Q Dong, B Tan, W Lim, S Zhou, W Duan

(2005), Vol. 65, pp. 4520-4524, Cancer research, Philadelphia, Pa., C1-1

journal article

Novel agents that potentially inhibit irinotecan-induced diarrhea

X Yang, Z Hu, S Chan, E Chan, B Goh, W Duan, S Zhou

(2005), Vol. 12, pp. 763-771, Current medicinal chemistry, Beijing, China, C1-1

journal article
2004

Effects of Salvia miltiorrhiza after acute myocardial infarction in rats

X Ji, B Tan, S Huang, M Whiteman, Y Zhu, W Duan, Y Zhu, W Linz

(2004), pp. 183-195, Novel compounds from natural products in the new millennium, Singapore, B1-1

book chapter

Signaling via a novel integral plasma membrane pool of a serine/threonine protein kinase PRK1 in mammalian cells

Y Zhu, D Stolz, F Guo, M Ross, S Watkins, J Bee, R Qi, E Manser, T Qiu, H Boon, S Tian, W Duan

(2004), Vol. 18, pp. 1722-1724, FASEB Journal, C1-1

journal article

The influence of magnetic fields exposure on neurite outgrowth in PC12 rat pheochromocytoma cells

W Fan, J Ding, W Duan, Y Zhu

(2004), Vol. 282, pp. 325-328, Journal of magnetism and magnetic materials, Amsterdam, The Netherlands, C1-1

journal article

Cytochrome bc1 regulates the mitochondrial permeability transition by two distinct pathways

J Armstrong, H Yang, W Duan, M Whiteman

(2004), Vol. 279, pp. 50420-50428, Journal of Biological Chemistry, C1-1

journal article

Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor U0126 in an asthma mouse model

W Duan, J Chan, C Wong, B Leung, W Wong

(2004), Vol. 172, pp. 7053-7059, Journal of immunology, Rockville, Md., C1-1

journal article

Inhibitor of p42/44 mitogen-activated protein kinase, but not p38 MAPK, attenuated antigen challenge of guinea pig airways in vitro

S Chue, C Seow, W Duan, K Yeo, A Koh, W Wong

(2004), Vol. 4, pp. 1089-1098, International immunopharmacology, Amsterdam, The Netherlands, C1-1

journal article
2003

Antiinflammatory effects of genistein, a tyrosine kinase inhibitor, on a guinea pig model of asthma

W Duan, I Kuo, S Selvarajan, K Chua, B Bay, W Wong

(2003), Vol. 167, pp. 185-192, American journal of respiratory and critical care medicine, New York, N.Y., C1-1

journal article
2002

Metallothionein 2A expression is associated with cell proliferation in breast cancer

R Jin, V Chow, P Tan, S Thameem Dheen, W Duan, B Bay

(2002), Vol. 23, pp. 81-86, Carcinogenesis, C1-1

journal article
2001

Identification of two proteins, S14 and UIP1, that interact with UCH37

T Li, W Duan, H Yang, M Lee, F Bte Mustafa, B Lee, T Teo

(2001), Vol. 488, pp. 201-205, FEBS Letters, C1-1

journal article
2000

Cloning and characterization of AWP1, a novel protein that associates with serine/threonine kinase PRK1 in vivo

W Duan, B Sun, T Li, B Tan, M Lee, T Teo

(2000), Vol. 256, pp. 113-121, Gene, Amsterdam, The Netherlands, C1-1

journal article
1995

Wallaby transthyretin

C Brack, W Duan, A Hulbert, G Schreiber

(1995), Vol. 110, pp. 523-529, Comparative biochemistry and physiology - part b: biochemistry & molecular biology, Amsterdam, The Netherlands, C1-1

journal article

Binding of thyroxine to pig transthyretin, its cDNA structure, and other properties

W Duan, S Richardson, J Kohrle, L Chang, B Southwell, P Harms, C Brack, T Pettersson, G Schreiber

(1995), Vol. 230, pp. 977-986, European journal of biochemistry, Chichester, Eng., C1-1

journal article

Homozygous deletions of the multiple tumor suppressor gene 1 in the progression of human astrocytomas

D Walker, W Duan, E Popovic, A Kaye, F Tomlinson, M Lavin

(1995), Vol. 55, pp. 20-23, Cancer research, Philadelphia, Pa., C1-1

journal article

Evolution of transthyretin in marsupials

W Duan, S Richardson, J Babon, R Heyes, B Southwell, P Harms, R Wettenhall, K Dziegielewska, L Selwood, A Bradley, C Brack, G Schreiber

(1995), Vol. 227, pp. 396-406, European journal of biochemistry, Chichester, Eng., C1-1

journal article
1994

Evolution of marsupial and other vertebrate thyroxine-binding plasma proteins

S Richardson, A Bradley, W Duan, R Wettenhall, P Harms, J Babon, B Southwell, S Nicol, S Donnellan, G Schreiber

(1994), Vol. 266, pp. R1359-R1370, American journal of physiology. Regulatory, integrative and comparative physiology, Bethesda, Md., C1-1

journal article
1993

The Expression of the Transthyretin Gene in Liver Evolved during the Radiation of Diprotodont Marsupials in Australia

S Richardson, A Bradley, W Duan, B Southwell, L Selwood, G Schreiber

(1993), Vol. 90, pp. 177-182, General and Comparative Endocrinology, New York, N.Y., C1-1

journal article

Thyroxine Transport to the Brain: Role of Protein Synthesis by the Choroid Plexus

B Southwell, W Duan, D Alcorn, C Brack, S Richardson, J Kohrle, G Schreiber

(1993), Vol. 133, pp. 2116-2126, Endocrinology, Oxford, Eng., C1-1

journal article

Transthyretin gene expression in choroid plexus first evolved in reptiles

M Achen, W Duan, T Pettersson, P Harms, S Richardson, M Lawrence, R Wettenhall, A Aldred, G Schreiber

(1993), Vol. 265, pp. R982-R989, American Journal of Physiology, Bethesda, Md., C1-1

journal article
1992

Expression of retinol-binding protein mRNA in mammalian choroid plexus

W Duan, G Schreiber

(1992), Vol. 101, pp. 399-406, Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology, Amsterdam, The Netherlands, C1-1

journal article
1991

Ontogenesis of transthyretin gene expression in chicken choroid plexus and liver

B SOUTHWELL, W DUAN, G TU, G SCHREIBER

(1991), Vol. 100, pp. 329-338, Comparative biochemistry and physiology part B: Comparative biochemistry, Amsterdam, The Netherlands, C1-1

journal article

Isolation, characterization, cDNA cloning and gene expression of an avian transthyretin: implications for the evolution of structure and function of transthyretin in vertebrates Isolation, characterization, cDNA cloning and gene

W DUAN, M ACHEN, S RICHARDSON, M LAWRENCE, R WETTENHALL, A JAWOROWSKI, G SCHREIBER

(1991), Vol. 200, pp. 679-687, European journal of biochemistry, Chichester, Eng., C1-1

journal article

Funded Projects at Deakin

Australian Competitive Grants

A novel tumour-targeting nanoliposome drug delivery system for the treatment of malignant gliomas

Prof Wei Duan, A/Prof Andrew Danks, Prof Sing Lo, A/Prof Qiu Tian Li

NHMRC Project Grant

  • 2010: $171,350
  • 2009: $168,157
  • 2008: $105,590

Developing molecularly targeted polymer nanoparticles for cancer therapeutics and diagnostics

Prof Wei Duan, Prof Qipeng Guo

DIISR/AISRF Grant - AISRF/India-Australian Strategic Research Fund - Department of Innovation, Industry, Science & Research

  • 2010: $29,200
  • 2009: $82,019
  • 2007: $210,000

Smart bombing of cancer stem cells using aptamer-guided nanoliposomal siRNA

Prof Wei Duan, Prof Lingxue Kong

DIISR/AISRF Grant - AISRF/India-Australian Strategic Research Fund - Department of Innovation, Industry, Science & Research

  • 2013: $75,000
  • 2012: $68,000
  • 2011: $112,000
  • 2010: $145,000

Peptide-based Star Nanocarriers for Targeted Anticancer Drug Delivery

Prof Greg Qiao, Prof Wei Duan, Dr Kenneth Dawson

ARC - Discovery Projects

  • 2016: $121,661
  • 2015: $54,996

Collaborative workshop on MEMS and its application in health care

Prof Lingxue Kong, Prof Wei Duan, Prof Abbas Kouzani, Prof Johnson Mak, Dr Sugumar Dharmalingam

DIISR/AISRF Grant - AISRF/India-Australian Strategic Research Fund - Department of Innovation, Industry, Science & Research

  • 2014: $31,000

Other Public Sector Funding

Link and Learn Grant

Prof Wei Duan

  • 2008: $5,000

Establishment of an aptamer-based technology platform for molecular targetting of cancer stem cell

Prof Wei Duan, A/Prof Andrew Danks, A/Prof Q Dong, Prof Lingxue Kong, A/Prof Jun-Ping Liu, Dr Jane Dai, Prof Michael Famulok, Prof Dominique Joubert

  • 2008: $136,346

Equipment Grant 2007

Prof Wei Duan

  • 2008: $81,082

Industry and Other Funding

Establishment of the First Medical School in Geelong

Prof Wei Duan, Prof Alister Ward, Prof Brendan Crotty

  • 2007: $30,000

Novel therapeutics to root out cancer

Prof Wei Duan

  • 2014: $15,000
  • 2013: $40,000

Tailored Neoadjuvant Epirubicin and Cyclophosphamide (EC) and Nanoparticle Albumin Bound (nab) Paclitaxel for Newly Diagnosed Breast Cancer

Dr Mustafa Khasraw, Prof Wei Duan

  • 2014: $66,500
  • 2013: $50,000

Glycomarker Panel for Prediction of IVF Outcome

Tracey Edgell, Prof Wei Duan

  • 2017: $1,000
  • 2016: $56,618
  • 2015: $55,043

Research into the role of Proteins called cytokine receptors in ovarian cancer and the development of novel agents to suppress their effects

Prof Alister Ward, Prof Wei Duan, Dr Daniel Mcculloch

  • 2015: $12,500
  • 2014: $12,500
  • 2013: $12,500

Development of nanoparticle-based delivery systems for Artemisia flavonoids for the treatment of hepatitis B

Prof Wei Duan

  • 2018: $495
  • 2017: $31,114

Development of novel aptamer-guided and exosome-based diagnostics and therapeutics

Prof Wei Duan

  • 2019: $80,000
  • 2018: $79,970
  • 2017: $80,000

Supervisions

Principal Supervisor
2020

Hridika Talukder Barua

Thesis entitled: Development of a novel exosome-based liquid biopsy assay for early detection of pancreatic cancer

Doctor of Philosophy (Medicine), School of Medicine

Yumei Zhang

Thesis entitled: Development of CD81 aptamers for extracellular vesicle-based theranostics

Doctor of Philosophy (Medicine), School of Medicine

2018

Wang Yin

Thesis entitled: Novel strategies to overcome drug resistance in liver cancer

Doctor of Philosophy (Medicine), School of Medicine

2016

Hadi Al Shamaileh

Thesis entitled: Aptamer-mediated siRNA delivery to target colon cancer stem cells

Doctor of Philosophy (Medicine), School of Medicine

2015

Dongxi Xiang

Thesis entitled: Developing RNA aptamer technology for targeting cancer stem cells

Doctor of Philosophy (Medicine), School of Medicine

2014

Tao Wang

Thesis entitled: An aptamer-mediated siRNA delivery system targeting breast tumourigenic cells

Doctor of Philosophy (Medicine), School of Medicine

Manju Marappan

Thesis entitled: Efficacy of utilizing chemical antibodies in histopathological studies

MAppSc (Medicine) (High cost), School of Medicine

2013

Jia Lin

Thesis entitled: A nanoliposome-based drug delivery system for cancer

Doctor of Philosophy (Medicine), School of Medicine

2010

Michael Stewart

Thesis entitled: Molting and Reproduction in Portunus Pelagicus

Doctor of Philosophy (Medicine), School of Medicine

Associate Supervisor
2020

Hao Fang

Thesis entitled: The role of IL-6 family signalling components in ovarian cancer

Doctor of Philosophy (Medicine), School of Medicine

2017

Joanna Michelle Macdonald

Thesis entitled: A bifunctional aptamer for the targeted treatment of brain metastases

Doctor of Philosophy (Medicine), School of Medicine

Xinchu Zhao

Thesis entitled: Gold Nanoparticles Based DNA Detection in Microfluidics

Doctor of Philosophy (Engineering), Institute for Frontier Materials

2016

Lijue Chen

Thesis entitled: Delivery of Fluorouracil and siRNA by Mesoporous Silica Nanoparticles to Drug Resistant Colorectal Cancer

Doctor of Philosophy (Engineering), Institute for Frontier Materials

2015

Xiaodong She

Thesis entitled: Tailored hollow mesoporous silica nanoplatforms with biological labels for colon targeted drug deliver systems

Doctor of Philosophy (Engineering), Institute for Frontier Materials

2014

Daryoush Mortazavi

Thesis entitled: DESIGN, MODELLING, FABRICATION, AND EVALUATION OF A TUNEABLE LSPR DEVICE

Doctor of Philosophy (Engineering), School of Engineering

2012

Yang Lim

Thesis entitled: Surface-Stress-Based Microcantilever Aptasensor

Doctor of Philosophy (Engineering), School of Engineering