Dr Yann Gibert



Clinical Associate Professor


Faculty of Health


School of Medicine


Off-Campus (Home)


Doctor of Natural Sciences, University of Konstanz, 2005


+61 3 522 71197


Dr. Yann Gibert obtained his BSc in Biology in 1997 from the University of Pau (France) and his MSc in Biochemistry in 2001 from the University of Limerick (Ireland). Dr. Gibert gained his PhD examining the roles played by the Retinoic Acid pathway during zebrafish embryonic development and using the zebrafish studied the evolution of genes implicated in non-channelopathy epilepsies in 2005 from the University of Konstanz (Germany).
After his PhD, Dr. Gibert worked as a post-doctoral fellow at the Institute of Functional Genomics of Lyon within the Ecole Normale Superieure of Lyon (France), broadening his interests into Retinoic Acid signalling and using the zebrafish as model for metabolic diseases. He then worked as a Research Fellow at Harvard Medical School, within the Beth Israel Deaconess Medical Centre, using the zebrafish to study the genetics of anemia and hemochromatosis.
Dr Gibert is the Head of the Metabolic Genetic Diseases Laboratory at Deakin School of Medicine (Australia). Dr Gibert’s team develop new techniques to study metabolism in vivo such as measuring metabolic respiration using the Seahorse Bio-analyzer and performing full lipidomic assay during vertebrate embryonic development using the zebrafish as model.

Read more on Yann's profile

Biography summary

1997 BSc, Major Biology University of Pau (France)

1999 Graduate Diploma, University of Limerick (Ireland)

2001 MSc in Biochemistry, University of Limerick (Ireland)

2005 PhD in Developmental Genetics, University of Konstanz (Germany)

2005-2007: Post-doctoral Fellow, Ecole Normale Superieure de Lyon (France)

2007-2010: Research Fellow, Harvard Medical School (Boston, MA, USA)

2010-2011: Reserach Assistant Professor, Tufts School of Medicine (Boston, MA, USA)

2011-present: Senior Lecturer, Head of the Metabolic Genetic Diseases Laboratory, Deakin School of Medicine (Australia)

Units taught

HMM102: Principles of Gene and Genomic Technology

HMM202: Molecular Diagnostics

Knowledge areas


Nuclear receptors biology

Zebrafish embryogenesis

Chemical Biology


Filter by


Release of hazardous nanoplastic contaminants due to microplastics fragmentation under shear stress forces

M Enfrin, J Lee, Y Gibert, F Basheer, L Kong, L Dume

(2020), Vol. 384, pp. 1-9, Journal of Hazardous Materials, Amsterdam, The Netherlands, C1

journal article

The protective effects of human milk-derived peptides on the pancreatic islet biology

Amitoj Singh, Ashwantha Enjapoori, Yann Gibert, Karen Dwyer

(2020), Vol. 9, pp. 1-20, Biology Open, Cambridge, Eng., C1

journal article

Suitability of novel algal biomass as fish feed: accumulation and distribution of omega-3 long-chain polyunsaturated fatty acid in Zebrafish

Avinesh Byreddy, Prusothman Yoganantharjah, Adarsha Gupta, Yann Gibert, Munish Puri

(2019), Vol. 188, pp. 112-123, Applied biochemistry and biotechnology, New York, N.Y., C1

journal article

Highly fluorescent and HDAC6 selective scriptaid analogues

Cassandra Fleming, Anthony Natoli, Jeannette Schreuders, Mark Devlin, Prusothman Yoganantharajah, Yann Gibert, Kathryn Leslie, Elizabeth New, Trent Ashton, Frederick Pfeffer

(2019), Vol. 162, pp. 321-333, European journal of medicinal chemistry, Amsterdam, The Netherlands, C1

journal article

High glucose levels affect retinal patterning during zebrafish embryogenesis

A Singh, Hozana Andrade Castillo, Julie Brown, Jan Kaslin, Karen Dwyer, Yann Gibert

(2019), Vol. 9, pp. 1-13, Scientific Reports, Berlin, Germany, C1

journal article

Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes

Avinash Soundararajan, Paramasivam Prabu, Viswanathan Mohan, Yann Gibert, Muthuswamy Balasubramanyam

(2019), Vol. 458, pp. 171-183, Molecular and cellular biochemistry, Amsterdam, The Netherlands, C1

journal article

The first formed tooth serves as a signalling centre to induce the formation of the dental row in zebrafish

Y Gibert, E Samarut, M Ellis, W Jackman, V Laudet

(2019), Vol. 286, pp. 1-9, Proceedings of the Royal Society B: biological sciences, London, Eng., C1

journal article

Bisphenol A exposure under metabolic stress induces accelerated cellular senescence in vivo in a p53 independent manner

A Soundararajan, P Yoganantharajah, S Raghavan, V Mohan, M Balasubramanyam, Y Gibert

(2019), Vol. 689, pp. 1201-1211, Science of the total environment, Amsterdam, The Netherlands, C1

journal article

Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity

M Dvalos-Salas, M Montgomery, C Reehorst, R Nightingale, I Ng, H Anderton, S Al-Obaidi, A Lesmana, C Scott, P Ioannidis, H Kalra, S Keerthikumar, L Tgel, A Rigopoulos, S Gong, D Williams, P Yoganantharaja, K Bell-Anderson, S Mathivanan, Y Gibert, S Hiebert, A Scott, M Watt, J Mariadason

(2019), Vol. 10, pp. 1-14, Nature Communications, Berlin, Germany, C1

journal article

Metformin, beta-cell development, and novel processes following beta-cell ablation in zebrafish

G Wyett, Y Gibert, M Ellis, H Castillo, J Kaslin, K Aston-Mourney

(2018), Vol. 59, pp. 419-425, Endocrine, Totowa, N.J., C1-1

journal article

The ADAMTS5 metzincin regulates zebrafish somite differentiation

Carolyn Dancevic, Yann Gibert, Joachim Berger, Adam Smith, Clifford Liongue, Nicole Stupka, Alister Ward, Daniel McCulloch

(2018), Vol. 19, pp. 1-12, International journal of molecular sciences, Basel, Switzerland, C1

journal article

Comparison of solvate ionic liquids and DMSO as an in vivo delivery and storage media for small molecular therapeutics

Prusothman Yoganantharajah, Alexander Ray, Daniel Eyckens, Luke Henderson, Yann Gibert

(2018), Vol. 18, pp. 1-7, BMC biotechnology, London, Eng., C1

journal article

The adenosine, adrenergic and opioid pathways in the regulation of insulin secretion, beta cell proliferation and regeneration

Amitoj Singh, Yann Gibert, Karen Dwyer

(2018), Vol. 18, pp. 615-623, Pancreatology, Amsterdam, The Netherlands, C1

journal article

The use of the zebrafish model to aid in drug discovery and target validation

P Yoganantharjah, Y Gibert

(2017), Vol. 17, pp. 2041-2055, Current topics in medicinal chemistry, Bussum, The Netherlands, C1

journal article

Rapid quantification of neutral lipids and triglycerides during zebrafish embryogenesis

P Yoganantharajah, A Byreddy, D Fraher, M Puri, Y Gibert

(2017), Vol. 61, pp. 105-111, International journal of developmental biology, Vizcaya, Spain, C1

journal article

A comparison of novel organoiridium(III) complexes and their ligands as a potential treatment for prostate cancer.

S Hockey, G Barbante, P Francis, J Altimari, P Yoganantharajah, Y Gibert, L Henderson

(2016), Vol. 109, pp. 305-313, European journal of medicinal chemistry, Amsterdam, The Netherlands, C1

journal article

Zebrafish embryonic lipidomic analysis reveals that the yolk cell as metabolically active in processing lipid

D Fraher, A Sanigorski, N Mellett, P Meikle, A Sinclair, Y Gibert

(2016), Vol. 14, pp. 1317-1329, Cell reports, Amsterdam, The Netherlands, C1

journal article

Solvate ionic liquids as reaction media for electrocyclic transformations

D Eyckens, M Champion, B Fox, P Yoganantharajah, Y Gibert, T Welton, L Henderson

(2016), Vol. 2016, pp. 913-917, European journal of organic chemistry, London, Eng., C1

journal article

A study on acute toxicity and solvent capacity of solvate ionic liquids: in vivo using a zebrafish model (Danio rerio)

P Yoganantharajah, D Eyckens, J Pedrina, L Henderson, Y Gibert

(2016), Vol. 40, pp. 6599-6603, New journal of chemistry, Cambridge, Eng., C1

journal article

ZebRA: an overview of retinoic acid signaling during zebrafish development.

E Samarut, D Fraher, V Laudet, Y Gibert

(2015), Vol. 1849, pp. 73-83, Biochimica et Biophysica Acta- gene regulatory mechanisms, Amsterdam, Netherlands, C1

journal article

Altered retinoic acid signalling underpins dentition evolution

Y Gibert, E Samarut, E Pasco-Viel, L Bernard, V Borday-Birraux, A Sadier, C Labb, L Viriot, V Laudet

(2015), Vol. 282, pp. 1-8, Proceedings of the royal society of London: biological sciences, London, Eng., C1

journal article

Lipid abundance in zebrafish embryos is regulated by complementary actions of the endocannabinoid system and retinoic acid pathway

D Fraher, M Ellis, S Morrison, S McGee, A Ward, K Walder, Y Gibert

(2015), Vol. 156, pp. 3596-3609, Endocrinology, Bethesda, Md., C1

journal article

Citalopram and sertraline exposure compromises embryonic bone development

D Fraher, J Hodge, F Collier, J McMillan, R Kennedy, M Ellis, G Nicholson, K Walder, S Dodd, M Berk, J Pasco, L Williams, Y Gibert

(2015), Vol. In press, pp. 1-9, Molecular psychiatry, Hampshire, Eng., C1

journal article

Rapid development of non-alcoholic steatohepatitis in Psammomys obesus (Israeli Sand Rat)

B Spolding, T Connor, C Wittmer, L Abreu, A Kaspi, M Ziemann, G Kaur, A Cooper, S Morrison, S Lee, A Sinclair, Y Gibert, J Trevaskis, J Roth, A El-Osta, R Standish, K Walder

(2014), Vol. 9, pp. 1-7, PLoS one, San Francisco, Calif., C1

journal article

Estrogen-related receptor ? is an in vivo receptor of bisphenol A

M Tohm, S Prud'Homme, A Boulahtouf, E Samarut, F Brunet, L Bernard, W Bourguet, Y Gibert, P Balaguer, V Laudet

(2014), Vol. 28, pp. 3124-3133, FASEB Journal, C1

journal article

Tissue Specific Roles for the Ribosome Biogenesis Factor Wdr43 in Zebrafish Development

C Zhao, V Andreeva, Y Gibert, M LaBonty, V Lattanzi, S Prabhudesai, Y Zhou, L Zon, K McCann, S Baserga, P Yelick

(2014), Vol. 10, PLoS Genetics, C1-1

journal article

The small molecule, genistein, increases hepcidin expression in human hepatocytes

A Zhen, N Nguyen, Y Gibert, S Motola, P Buckett, M Wessling-Resnick, E Fraenkel, P Fraenkel

(2013), Vol. 58, pp. 1315-1325, Hepatology, C1

journal article

Zebrafish as a genetic model in pre-clinical drug testing and screening

Y Gibert, M Trengove, A Ward

(2013), Vol. 20, pp. 2458-2466, Current Medicinal Chemistry, C1

journal article

Metabolic profile analysis of zebrafish embryos

Y Gibert, S McGee, A Ward

(2013), Vol. 71, pp. 1-5, Journal of visualized experiments, Cambridge, Mass., C1

journal article

Retinoic acid expands the evolutionarily reduced dentition of zebrafish

P Seritrakul, E Samarut, T Lama, Y Gibert, V Laudet, W Jackman

(2012), Vol. 26, pp. 5014-5024, FASEB Journal, C1-1

journal article

Fasting induces CART down-regulation in the zebrafish nervous system in a cannabinoid receptor 1-dependent manner

S Nishio, Y Gibert, L Berekelya, L Bernard, F Brunet, E Guillot, J Le Bail, J Snchez, A Galzin, G Triqueneaux, V Laudet

(2012), Vol. 26, pp. 1316-1326, Molecular Endocrinology, C1-1

journal article

Bisphenol A induces otolith malformations during vertebrate embryogenesis

Y Gibert, S Sassi-Messai, J Fini, L Bernard, D Zalko, J Cravedi, P Balaguer, M Andersson-Lendahl, B Demeneix, V Laudet

(2011), Vol. 11, BMC Developmental Biology, C1-1

journal article

BMP signaling modulates Hepcidin expression in zebrafish embryos independent of Hemojuvelin

Y Gibert, V Lattanzi, A Zhen, L Vedder, F Brunet, S Faasse, J Babitt, H Lin, M Hammerschmidt, P Fraenkel

(2011), Vol. 6, PLoS ONE, C1-1

journal article

Formation of oral and pharyngeal dentition in teleosts depends on differential recruitment of retinoic acid signaling

Y Gibert, L Bernard, M Debiais-Thibaud, F Bourrat, J Joly, K Pottin, A Meyer, S Retaux, D Stock, W Jackman, P Seritrakul, G Begemann, V Laudet

(2010), Vol. 24, pp. 3298-3309, FASEB Journal, C1-1

journal article

Transferrin-a modulates hepcidin expression in zebrafish embryos

P Fraenkel, Y Gibert, J Holzheimer, V Lattanzi, S Burnett, K Dooley, R Wingert, L Zon

(2009), Vol. 113, pp. 2843-2850, Blood, C1-1

journal article

The phytoestrogen genistein affects zebrafish development through two different pathways

S Sassi-Messai, Y Gibert, L Bernard, S Nishio, L Ferri, J Molina, M Andersson-Lendhal, G Benoit, P Balaguer, V Laudet

(2009), Vol. 4, pp. 1-13, PLoS one, San Francisco, California, C1-1

journal article

Adiponectin and adiponectin receptor genes are coexpressed during zebrafish embryogenesis and regulated by food deprivation

S Nishio, Y Gibert, L Bernard, F Brunet, G Triqueneaux, V Laudet

(2008), Vol. 237, pp. 1682-1690, Developmental Dynamics, C1-1

journal article

Induction and prepatterning of the zebrafish pectoral fin bud requires axial retinoic acid signaling

Y Gibert, A Gajewski, A Meyer, G Begemann

(2006), Vol. 133, pp. 2649-2659, Development, C1-1

journal article

Using gene-history and expression analyses to assess the involvement of LGI genes in human disorders

W Gu, Y Gibert, T Wirth, A Elischer, W Bloch, A Meyer, O Steinlein, G Begemann

(2005), Vol. 22, pp. 2209-2216, Molecular Biology and Evolution, C1-1

journal article

Analysis of the very large G-protein coupled receptor gene (Vlgr1/Mass1/USH2C) in zebrafish

Y Gibert, D McMillan, K Kayes-Wandover, A Meyer, G Begemann, P White

(2005), Vol. 353, pp. 200-206, Gene, C1-1

journal article

Cloning of zebrafish T-box genes tbx15 and tbx18 and their expression during embryonic development

G Begemann, Y Gibert, A Meyer, P Ingham

(2002), Vol. 114, pp. 137-141, Mechanisms of Development, C1-1

journal article

Isolation and characterisation of the ylmE homologue of thermus thermophilus

S Spada, Y Gibert, J Pembroke, J Wall

(2001), Vol. 11, pp. 507-514, Mitochondrial DNA, C1-1

journal article

Cloning and characterisation of the hint homologue of the thermophile thermus thermophilus

Y Gibert, S Spada, J Wall, J Pembroke

(2001), Vol. 12, pp. 179-185, Mitochondrial DNA, C1-1

journal article

Funded Projects at Deakin

Australian Competitive Grants

Roles of bisphenols A, S and AF in the development of diabetes and obesity

Dr Yann Gibert

DART Grant - Research - Diabetes Australia - Victoria (Research Trust)

  • 2014: $57,520

Industry and Other Funding

Automated gene expression quantification machine: qRT-PCR

Dr Yann Gibert, Prof Alister Ward

  • 2014: $33,800


Principal Supervisor

Prusothman Yoganantharajah

Thesis entitled: Zebrafish: Drug discovery, toxicity testing and chemical modulators of lipids

Doctor of Philosophy (Medicine), School of Medicine


Daniel Fraher

Thesis entitled: Chemical Modulators of Lipid Abundance and Bone Development

Doctor of Philosophy (Medicine), School of Medicine

Associate Supervisor

Natasha Lee McRae

Thesis entitled: Targeting versican as a therapeutic strategy in Duchenne muscular dystrophy

Doctor of Philosophy (Medicine), School of Medicine


Monique Trengove

Thesis entitled: Suppressor of cytokine signalling 4 and 5 in zebrafish development

Doctor of Philosophy (Medicine), School of Medicine

Carolyn Dancevic

Thesis entitled: Dissecting ADAMTS Proteoglycanase Biology in Development and Disease

Doctor of Philosophy (Medicine), School of Medicine