Profile image of Alister Ward

Prof Alister Ward

STAFF PROFILE

Position

Professor of Molecular Medicine

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Qualifications

Bachelor of Arts, University of Melbourne, 2001
Doctor of Philosophy, University of Melbourne, 1994
Bachelor of Science, University of Melbourne, 1989

Contact

alister.ward@deakin.edu.au
+61 3 522 72041

Research interests

The immune system is vital for maintaining good health. However, much remains to be learnt about how it develops normally, how it is perturbed in disease and how it is subverted during infection. One key facet of the immune system are the various cytokines and their receptors that regulate it. Prof. Ward leads a research team at Deakin University’s new Medical School investigating the genes involved in the development of the immune system, including cytokine receptor signalling components, with the aim of understanding their function, evolution, and role in disease. This research utilises multi-disciplinary approach, combining bioinformatics, molecular biology and functional genomics approaches in the zebrafish model.
Prof. Ward’s group is housed in the $15M Molecular Medicine Research Facility, which opened in April 2011 and contains a comprehensive suite of equipment to service molecular biology, cell biology, microscopy and histology at PC2 level. CI-Ward also oversees the ARC LIEF-funded FishWorks facility, which consists of an extensive Aquatic Habitats aquarium with a 700-tank capacity, including breeding tanks, independent light cycles, and nursery, as well as an exquisite range of equipment for zebrafish embryo manipulation and analysis, including dedicated microinjectors, fluorescence microscopes and digital cameras, and currrenlty being further upgraded.

Teaching interests

Prof. Ward has significant teaching expertise, previously serving as Year 1 & 2 Co-ordinator for Medicine and Course Director for Biomedical Science. He currently teaches into ‘Human Biology’ and ‘Infection, Defence & Repair’ in the Medical Course and ‘Immunology & Hematology’ in Biomedical Sciences, and contributes to the supervision of 3rd year, Intern, Honours and PhD students.

Knowledge areas

Prof. Ward was awarded a Bachelor of Science (Honours), Bachelor of Arts and Doctor of Philosophy from the University of Melbourne, and has then trained as a European Molecular Biology Organisation Long-Term Fellow and a Sylvia and Charles Viertel Senior Medical Research Fellow. This has provided him with significant expertise in biochemistry, genetics, functional genomics, bioinformatics, immunology, haematology and developmental biology.

Professional activities

CI-Ward has a strong presence in the local, national and international research community, illustrated by the following specific activities:

> Conference Organisation:
• 8th Australian & New Zealand Zebrafish Workshop, Geelong, Australia (2007)
- Organising Committee (Chair)
• Infection & Immunity Conference, Gold Coast, Australia (2009)
- Scientific Advisory Committee
• Emerging Infectious Diseases Conference, Geelong, Australia (2012)
- Scientific Advisory Committee
• 4th International One Health Conference, Melbourne, Australia (2016)
- Organising Committee

> Grant Review:
• Australian Research Council
- International Reader (2004-)
- College of Experts Member (2013-)
• National Health & Medical Research Council
- Project Grant Reviewer (2001-)
- Grant Review Panel Member (2011)

> Editorial Roles:
• Frontiers in Bioscience, Special Issue: ‘Granulocyte colony-stimulating factor and its receptor: roles in health and disease’
- Managing Editor (2007)
• JAK-STAT
- Editorial Board Member (2012-)
• American Journal of Experimental and Clinical Immunology
- Editorial Board Member (2012-)
• Journal of Blood Diseases
- Editorial Board Member (2014-)

> Other Peer Review, etc:
• Regular manuscripts from >15 journals, including Blood, Haematologica, and J Immunol
• Judging panels, including ASMR Vic. Premier’s Award (2006-11,14), SMART Geelong Awards (2010,12-13)
• Regular theses (1-2/year)

> Research Training:
• BSc(Hons):
- 10 completed (9 with H1 – 3 top of cohort, 9 continued to PhD)
• PhD:
- 9 completed (4 prize-winners, all continued to postdoc/faculty roles, incl. at WEHI, Peter MacCallum Cancer Institute, University College London)
- 9 current

> Leadership/Representative Roles:
• Australian Society for Biochemistry & Molecular Biology
- Review Panellist (2004)
• Australian Society for Medical Research
- Medical Research Week Committee (2000-5)
- Careers Sub-Committee (2000-4)
- Assistant to the Premier’s Award (2002-5)
- Premier’s Award Sub-Committee (2004-5), Chair (2004-5)
• BioGeelong
- Steering Committee Chair (2008-10)
• Geelong Centre for Emerging Infectious Diseases
- Steering Committee (2009-)
• Biosciences Victoria
- Deakin University rep (2010-2)
• Victorian Technology Network
- Deakin University rep (2010-)
• Research Australia
- Deakin University rep (2011)

Awards

Consistently successful at obtaining competitive funding, Professor Ward has been awarded funds totalling in excess of $4.2 million, with the majority from National Competitive Grant Schemes. He has also received a number of prestigious fellowships, including a European Molecular Biology Organisation Long-Term Fellowship, an AMRAD Postdoctoral Award and a Sylvia and Charles Viertel Senior Medical Research Fellowship. In the last 10 years these include:
• Australian Research Council Discovery Project Grant, ‘Socs proteins in health and disease’, 2005-2007 $215 000 (CI: AC Ward)
• Australian & Pacific Science Foundation Grant, ‘Impact of subterranean water on the physiology and health of Murray Cod (Maccullochella peeli peeli)’, 2006-2008 $28 000 (CIs: P Jones, S De Silva, G Turchini, T Toop, AC Ward)
• Geelong Community Foundation Grant, ‘Establishment of medical school’, 2007 $30 000 (CIs: W Duan, B Crotty, AC Ward)
• National Health & Medical Research Council Enabling Grant, ‘Australian zebrafish phenomics facility’, 2007-2011 $1 500 000 (CIs: A Perkins, B Key, J Rothnagel, A Ward, S Grimmond, P Alewood, D Hume, A Boyd, M Lardelli)
• Geelong Community Foundation, ‘Establishment of GTRAC’, 2009 $47 000 (CI: AC Ward)
• The Foundation for Children, ‘Defining mechanisms underlying skeletal muscle development and muscular dystrophy’, 2010-2012 $157 000 (CIs: D McCulloch, N Stupka, AC Ward)
• Collier Charitable Fund, ‘Study of embryonic development: automatic gene detection device’, 2012 $48 000 (CIs: Y Gibert, AC Ward)
• Australian Research Council Linkage Infrastructure Equipment Fund Grant, ‘Collaborative high bio-containment immunological research facility’, 2012 $520 000 (CIs: AC Ward, J Mak, LF Wang, J Stambas, J Lowenthal, R Tripp, TF de Koning-Ward, WA Buttemer)
• Atkins Charitable Trust, ‘Role of cytokine receptors in ovarian cancer’, 2012-2015 $42 500 (CIs: AC Ward, W Duan, D McCulloch)

Publications

Filter by

2024

Contribution of Signal Transducer and Activator of Transcription 3 (STAT3) to Bone Development and Repair

Mohamed Sobah, Clifford Liongue, Alister Ward

(2024), Vol. 25, pp. 1-16, International Journal of Molecular Sciences, Basel, Switzerland, C1

journal article

Signal Transducer and Activator of Transcription Proteins at the Nexus of Immunodeficiency, Autoimmunity and Cancer

Clifford Liongue, Mohamed Sobah, Alister Ward

(2024), Vol. 12, pp. 1-14, Biomedicines, Basel, Switzerland, C1

journal article

Myeloproliferative Neoplasms: Diseases Mediated by Chronic Activation of Signal Transducer and Activator of Transcription (STAT) Proteins

Clifford Liongue, Alister Ward

(2024), Vol. 16, pp. 1-13, Cancers, Basel, Switzerland, C1

journal article

Immune Factors, Immune Cells and Inflammatory Diseases

Alister Ward

(2024), Vol. 25, pp. 1-2, International Journal of Molecular Sciences, Basel, Switzerland, C1

journal article

Janus Kinase 3 (JAK3): A Critical Conserved Node in Immunity Disrupted in Immune Cell Cancer and Immunodeficiency

C Liongue, T Ratnayake, F Basheer, A Ward

(2024), Vol. 25, pp. 1-13, International Journal of Molecular Sciences, Basel, Switzerland, C1

journal article
2023

Leukemia-associated truncation of granulocyte colony-stimulating factor receptor impacts granulopoiesis throughout the life-course

V Bulleeraz, M Goy, F Basheer, C Liongue, A Ward

(2023), Vol. 13, pp. 1095453-, Frontiers in Immunology, Switzerland, C1

journal article

Zebrafish: A Relevant Genetic Model for Human Primary Immunodeficiency (PID) Disorders?

F Basheer, R Sertori, C Liongue, A Ward

(2023), Vol. 24, pp. 1-17, International Journal of Molecular Sciences, Basel, Switzerland, C1

journal article

A zebrafish model of growth hormone insensitivity syndrome with immune dysregulation 1 (GHISID1)

Somayyeh Heidary, Nagendra Awasthi, Nicole Page, Theo Allnutt, Rowena Lewis, Clifford Liongue, Alister Ward

(2023), Vol. 80, pp. 1-12, Cellular and Molecular Life Sciences, Berlin, Germany, C1

journal article

Socs3b regulates the development and function of innate immune cells in zebrafish

M Sobah, A Scott, M Laird, C Koole, C Liongue, A Ward

(2023), Vol. 14, pp. 01-15, Frontiers in Immunology, Lausanne, Switzerland, C1

journal article

The Role of Cytokine-Inducible SH2 Domain-Containing Protein (CISH) in the Regulation of Basal and Cytokine-Mediated Myelopoiesis

W Naser, S Maymand, D Dlugolenski, F Basheer, A Ward

(2023), Vol. 24, pp. 1-10, International Journal of Molecular Sciences, Basel, Switzerland, C1

journal article

Analysis of Potential Non-Canonical or Alternate STAT5 Functions in Immune Development and Growth

N Awasthi, A Ward, C Liongue

(2023), Vol. 28, pp. 1-10, Frontiers in Bioscience, Singapore, C1

journal article

Role of Cytokine-Inducible SH2 Domain-Containing (CISH) Protein in the Regulation of Erythropoiesis

Saeed Maymand, Asha Lakkavaram, Wasan Naser, Parisa Rasighaemi, Daniel Dlugolenski, Clifford Liongue, John Stambas, Tania de Koning-Ward, Alister Ward

(2023), Vol. 13, pp. 1-11, Biomolecules, Basel, Switzerland, C1

journal article

Cish knockout mice exhibit similar outcomes to malaria infection despite altered hematopoietic responses

A Lakkavaram, S Maymand, W Naser, A Ward, T de Koning-Ward

(2023), Vol. 14, pp. 1-12, Frontiers in Microbiology, Lausanne, Switzerland, C1

journal article
2022

Generation and Characterization of a Zebrafish IL-2Rγc SCID Model

R Sertori, R Jones, F Basheer, L Rivera, S Dawson, S Loke, S Heidary, A Dhillon, C Liongue, A Ward

(2022), Vol. 23, pp. 1-13, International Journal of Molecular Sciences, Basel, Switzerland, C1

journal article

Functional Analysis of Zebrafish socs4a: Impacts on the Notochord and Sensory Function

M Trengove, R Wyett, C Liongue, A Ward

(2022), Vol. 12, pp. 1-12, Brain Sciences, Basel, Switzerland, C1

journal article

Granulocyte Colony-Stimulating Factor Mediated Regulation of Early Myeloid Cells in Zebrafish

A Meier, F Basheer, R Sertori, M Laird, C Liongue, A Ward

(2022), Vol. 27, pp. 1-7, Frontiers in Bioscience - Landmark, Singapore, C1

journal article

Cytokine-inducible SH2 domain containing protein contributes to regulation of adiposity, food intake, and glucose metabolism

W Naser, S Maymand, L Rivera, T Connor, C Liongue, C Smith, K Aston-Mourney, D McCulloch, S McGee, A Ward

(2022), Vol. 36, pp. 1-15, FASEB Journal, London, Eng., C1

journal article

In vivo impact of JAK3 A573V mutation revealed using zebrafish

F Basheer, V Bulleeraz, V Ngo, C Liongue, A Ward

(2022), Vol. 79, Cellular and Molecular Life Sciences, Switzerland, C1

journal article

Cytokine Receptor-Like Factor 3 (CRLF3) Contributes to Early Zebrafish Hematopoiesis

T Taznin, K Perera, Y Gibert, A Ward, C Liongue

(2022), Vol. 13, pp. 910428-, Frontiers in Immunology, Switzerland, C1

journal article

Phylogenetic and Expression Analysis of Fos Transcription Factors in Zebrafish

K Kubra, G Gaddu, C Liongue, S Heidary, A Ward, A Dhillon, F Basheer

(2022), Vol. 23, International Journal of Molecular Sciences, Switzerland, C1

journal article

Zebrafish Model of Severe Combined Immunodeficiency (SCID) Due to JAK3 Mutation

F Basheer, E Lee, C Liongue, A Ward

(2022), Vol. 12, Biomolecules, Switzerland, C1

journal article

B cell lymphoma 6A regulates immune development and function in zebrafish

F Almohaisen, S Heidary, M Sobah, A Ward, C Liongue

(2022), Vol. 12, pp. 01-14, Frontiers in Cellular and Infection Microbiology, Lausanne, Switzerland, C1

journal article
2021

The role of the metzincin superfamily in prostate cancer progression: A systematic-like review

M Binder, A Ward

(2021), Vol. 22, International Journal of Molecular Sciences, Switzerland, C1

journal article

The endocannabinoid system and retinoic acid signaling combine to influence bone growth

D Fraher, R Mann, M Dubuisson, M Ellis, T Yu, K Walder, A Ward, C Winkler, Y Gibert

(2021), Vol. 529, Molecular and Cellular Endocrinology, Ireland, C1

journal article

SOCS Proteins in Immunity, Inflammatory Diseases, and Immune-Related Cancer

M Sobah, C Liongue, A Ward

(2021), Vol. 8, Frontiers in Medicine, Switzerland, C1

journal article

STAT proteins: a kaleidoscope of canonical and non-canonical functions in immunity and cancer

N Awasthi, C Liongue, A Ward

(2021), Vol. 14, Journal of Hematology and Oncology, England, C1

journal article
2020

Folate levels in pregnancy and offspring food allergy and eczema

J Molloy, F Collier, R Saffery, K Allen, J Koplin, A Louise Ponsonby, M Tang, A Ward, D Martino, D Burgner, J Carlin, S Ranganathan, C Symeonedies, T Dwyer, P Vuillermin

(2020), Vol. 31, pp. 38-46, Pediatric allergy and immunology, Chichester, Eng., C1

journal article

ADAMTS-15 has a tumor suppressor role in prostate cancer

M Binder, S McCoombe, E Williams, D McCulloch, A Ward

(2020), Vol. 10, Biomolecules, Switzerland, C1

journal article

Acute Plasmodium berghei Mouse Infection Elicits Perturbed Erythropoiesis With Features That Overlap With Anemia of Chronic Disease

A Lakkavaram, R Lundie, H Do, A Ward, T de Koning-Ward

(2020), Vol. 11, Frontiers in Microbiology, Switzerland, C1

journal article

Zebrafish Bacterial Infection Assay to Study Host-Pathogen Interactions

Faiza Basheer, Clifford Liongue, Alister Ward

(2020), Vol. 10, BIO-PROTOCOL, United States, C1

journal article
2019

Zebrafish granulocyte colony-stimulating factor receptor maintains neutrophil number and function throughout the life span

F Basheer, P Rasighaemi, C Liongue, A Ward

(2019), Vol. 87, Infection and Immunity, United States, C1

journal article
2018

The ADAMTS5 metzincin regulates zebrafish somite differentiation

C Dancevic, Y Gibert, J Berger, A Smith, C Liongue, N Stupka, A Ward, D McCulloch

(2018), Vol. 19, International Journal of Molecular Sciences, Switzerland, C1

journal article

Zebrafish as a model to evaluate nanoparticle toxicity

E Haque, A Ward

(2018), Vol. 8, Nanomaterials, Switzerland, C1

journal article

Hyperactivation of oncogenic JAK3 mutants depend on ATP binding to the pseudokinase domain

J Raivola, H Hammarén, A Virtanen, V Bulleeraz, A Ward, O Silvennoinen

(2018), Vol. 8, Frontiers in Oncology, Switzerland, C1

journal article

Recent advances in graphene quantum dots: Synthesis, properties, and applications

E Haque, J Kim, V Malgras, K Raghava Reddy, A Ward, J You, Y Bando, M Hossain, Y Yamauchi

(2018), Vol. 2, pp. 1-14, Small Methods, C1

journal article
2017

The extracellular matrix in cancer progression: role of hyalectan proteoglycans and ADAMTS enzymes

M Binder, S McCoombe, E Williams, D McCulloch, A Ward

(2017), Vol. 385, pp. 55-64, Cancer letters, Amsterdam, The Netherlands, C1

journal article

Vitamin D insufficiency in the first 6 months of infancy and challenge-proven IgE-mediated food allergy at 1 year of age: a case-cohort study

J Molloy, J Koplin, K Allen, M Tang, F Collier, J Carlin, R Saffery, D Burgner, S Ranganathan, T Dwyer, A Ward, M Moreno-Betancur, M Clarke, A Ponsonby, P Vuillermin

(2017), Vol. 72, pp. 1222-1231, Allergy: European Journal of Allergy and Clinical Immunology, Denmark, C1

journal article

shRNAs targeting either the glycoprotein or polymerase genes inhibit viral haemorrhagic septicaemia virus replication in zebrafish ZF4 cells

B Clarke, K McColl, A Ward, T Doran

(2017), Vol. 141, pp. 124-132, Antiviral research, Amsterdam, The Netherlands, C1

journal article

ETV6 and ETV7: siblings in hematopoiesis and its disruption in disease

P Rasighaemi, A Ward

(2017), Vol. 116, pp. 106-115, Critical Reviews in Oncology/Hematology, Shannon, Clare Ireland, C1

journal article

Leptin receptor signaling via Janus kinase 2/Signal transducer and activator of transcription 3 impacts on ovarian cancer cell phenotypes

J Kumar, H Fang, D McCulloch, T Crowley, A Ward

(2017), Vol. 8, pp. 93530-93540, Oncotarget, Albany, N.Y., C1

journal article

Granulocyte Colony-Stimulating Factor and Its Potential Application for Skeletal Muscle Repair and Regeneration

C Wright, A Ward, A Russell

(2017), Vol. 2017, Mediators of Inflammation, United States, C1

journal article
2016

Conserved IL-2Rγc signaling mediates lymphopoiesis in zebrafish

R Sertori, C Liongue, F Basheer, K Lewis, P Rasighaemi, D De Coninck, D Traver, A Ward

(2016), Vol. 196, pp. 135-143, Journal of Immunology, United States, C1

journal article

Signaling via the CytoR/JAK/STAT/SOCS pathway: Emergence during evolution

C Liongue, T Taznin, A Ward

(2016), Vol. 71, pp. 166-175, Molecular Immunology, England, C1

journal article

Evolution of cytokine receptor signaling

C Liongue, R Sertori, A Ward

(2016), Vol. 197, pp. 11-18, Journal of Immunology, United States, C1

journal article

The ADAMTS hyalectanase family: Biological insights from diverse species

C Dancevic, D McCulloch, A Ward

(2016), Vol. 473, pp. 2011-2022, Biochemical Journal, England, C1

journal article

Genome editing in zebrafish: a practical overview

R Sertori, M Trengove, F Basheer, A Ward, C Liongue

(2016), Vol. 15, pp. 322-330, Briefings in functional genomics, Oxford, Eng., C1

journal article
2015

Cytokine networks and cancer stem cells

C Liongue, A Ward, W Duan, S Shigdar

(2015), pp. 67-87, Cancer stem cells : emerging concepts and future perspectives in translational oncology, Berlin, Germany, B1

book chapter

ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish

P Rasighaemi, S Onnebo, C Liongue, A Ward

(2015), Vol. 100, pp. 23-31, Haematologica, Pavia, Italy, C1

journal article

Characterisation of chicken viperin

K Goossens, A Karpala, A Rohringer, A Ward, A Bean

(2015), Vol. 63, pp. 373-380, Molecular immunology, Amsterdam, The Netherlands, C1

journal article

G-CSF treatment can attenuate dexamethasone-induced reduction in C2C12 myotube protein synthesis

C Wright, E Brown, A Ward, A Russell

(2015), Vol. 73, pp. 1-7, Cytokine, Amsterdam, The Netherlands, C1

journal article

The evolutionary conservation of the A Disintegrin-like and Metalloproteinase domain with Thrombospondin-1 motif metzincins across vertebrate species and their expression in teleost zebrafish

F Brunet, F Fraser, M Binder, A Smith, C Kintakas, C Dancevic, A Ward, D McCulloch

(2015), Vol. 15, pp. 1-15, BMC evolutionary biology, London, Eng., C1

journal article

Functional analysis of truncated forms of ETV6

P Rasighaemi, C Liongue, S Onnebo, A Ward

(2015), Vol. 171, pp. 658-662, British journal of haematology, Chichester, Eng., C1

journal article

Zebrafish as a model for leukemia and other hematopoietic disorders

P Rasighaemi, F Basheer, C Liongue, A Ward

(2015), Vol. 8, pp. 1-10, Journal of hematology & oncology, London, Eng., C1

journal article

Is low vitamin D status a risk factor for food allergy? Current evidence and future directions

J Molloy, A Ponsonby, K Allen, M Tang, F Collier, A Ward, J Koplin, P Vuillermin

(2015), Vol. 15, pp. 944-952, Mini-Reviews in Medicinal Chemistry, Netherlands, C1

journal article

Lipid abundance in zebrafish embryos is regulated by complementary actions of the endocannabinoid system and retinoic acid pathway

D Fraher, M Ellis, S Morrison, S McGee, A Ward, K Walder, Y Gibert

(2015), Vol. 156, pp. 3596-3609, Endocrinology, Bethesda, Md., C1

journal article

EpCAM aptamer-mediated survivin silencing sensitized cancer stem cells to doxorubicin in a breast cancer model

T Wang, M Gantier, D Xiang, A Bean, M Bruce, S Zhou, M Khasraw, A Ward, L Wang, M Wei, H AlShamaileh, L Chen, X She, J Lin, L Kong, S Shigdar, W Duan

(2015), Vol. 5, pp. 1456-1472, Theranostics, Wyoming, N.S.W., C1

journal article
2014

Cytokine receptor signaling in teleosts

A Ward, R Sertori, C Liongue

(2014), pp. 39-72, Teleosts: evolutionary development, diversity and behavioral ecology, New York, N.Y., B1

book chapter

Granulocyte colony-stimulating factor receptor signalling via Janus kinase 2/signal transducer and activator of transcription 3 in ovarian cancer

J Kumar, F Fraser, C Riley, N Ahmed, D McCulloch, A Ward

(2014), Vol. 110, pp. 133-145, British Journal of Cancer, London, England, C1

journal article

Regulation of embryonic hematopoiesis by a cytokine-inducible SH2 domain homolog in zebrafish

R Lewis, S Noor, F Fraser, R Sertori, C Liongue, A Ward

(2014), Vol. 192, pp. 5739-5748, Journal of Immunology, United States, C1

journal article

Role of the interleukin 6 receptor family in epithelial ovarian cancer and its clinical implications.

J Kumar, A Ward

(2014), Vol. 1845, pp. 117-125, Biochimica et biophysica acta, Amsterdam, The Netherlands, C1

journal article

G-CSF does not influence C2C12 myogenesis despite receptor expression in healthy and dystrophic skeletal muscle

C Wright, E Brown, P Della-Gatta, A Ward, G Lynch, A Russell

(2014), Vol. 5, pp. 1-13, Frontiers in physiology, Lausanne, Switzerland, C1

journal article

Granulocyte colony-stimulating factor receptor mutations in myeloid malignancy

C Liongue, A Ward

(2014), Vol. 4, pp. 1-7, Frontiers in oncology, Lausanne, Switzerland, C1

journal article

Characterisation of chicken ZAP

K Goossens, A Karpala, A Ward, A Bean

(2014), Vol. 46, pp. 373-381, Developmental & comparative immunology, Amsterdam, The Netherlands, C1

journal article

ETV6 (TEL1) in blood cell development and malignancy

P Rasighaemi, C Liongue, A Ward

(2014), Vol. 1, pp. 1-7, Journal of blood disorders, Monroe Township, NJ, C1

journal article
2013

Zebrafish as a genetic model in pre-clinical drug testing and screening

Y Gibert, M Trengove, A Ward

(2013), Vol. 20, pp. 2458-2466, Current Medicinal Chemistry, Hilversum, Netherlands, C1

journal article

Metabolic profile analysis of zebrafish embryos

Y Gibert, S McGee, A Ward

(2013), Vol. 71, pp. 1-5, Journal of visualized experiments, Cambridge, Mass., C1

journal article

Chicken interferons, their receptors and interferon-stimulated genes

K Goossens, A Ward, J Lowenthal, A Bean

(2013), Vol. 41, pp. 370-376, Developmental and Comparative Immunology, United Kingdom, C1

journal article

Pegasus, the 'atypical' Ikaros family member, influences left-right asymmetry and regulates pitx2 expression

L John, M Trengove, F Fraser, S Yoong, A Ward

(2013), Vol. 377, pp. 46-54, Developmental Biology, Maryland Heights, Mo., C1

journal article

Versican processing by a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats proteinases-5 and -15 facilitates myoblast fusion

N Stupka, C Kintakas, J White, F Fraser, M Hanciu, N Aramaki-Hattori, S Martin, C Coles, F Collier, A Ward, S Apte, D McCulloch

(2013), Vol. 288, pp. 1907-1917, Journal of biological chemistry, Bethesda, Maryland, C1

journal article

Evolution of the JAK-STAT pathway

C Liongue, A Ward

(2013), Vol. 2, JAK-STAT, Austin, Tex., C1

journal article

Characterization of zebrafish polymerase iii promoters for the expression of short hairpin RNA interference molecules

B Clarke, D Cummins, K McColl, A Ward, T Doran

(2013), Vol. 10, pp. 472-479, Zebrafish, New Rochelle, NY, C1

journal article

The potential link between gut microbiota and IgE-mediated food allergy in early life

J Molloy, K Allen, F Collier, M Tang, A Ward, P Vuillermin

(2013), Vol. 10, pp. 7235-7256, International journal of environmental research and public health, Basel, Switzerland, C1

journal article

SOCS proteins in development and disease

M Trengove, A Ward

(2013), Vol. 2, pp. 1-29, American journal of clinical and experimental immunology, Madison, Wi., C1

journal article

Biosynthesis and expression of a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats-15

C Dancevic, F Fraser, A Smith, N Stupka, A Ward, D McCulloch

(2013), Vol. 288, pp. 37267-37276, Journal of Biological Chemistry, Rockville, Md., C1

journal article
2012

Evolution of JAK-STAT pathway components : mechanisms and role in immune system development

C Liongue, L O'Sullivan, M Trengove, A Ward

(2012), Vol. 7, pp. 1-16, PLoS one, San Francisco, Calif., C1

journal article

Koi herpesvirus encodes and expresses a functional interleukin-10

A Sunarto, C Liongue, K McColl, M Adams, D Bulach, M Crane, K Schat, B Slobedman, A Barnes, A Ward, P Walker

(2012), Vol. 86, pp. 11512-11520, Journal of virology, Washington, D.C., C1

journal article

Alternative TEL-JAK2 fusions associated with T-cell acute lymphoblastic leukemia and atypical chronic myelogenous leukemia dissected in zebrafish

S Onnebo, P Rasighaemi, J Kumar, C Liongue, A Ward

(2012), Vol. 97, pp. 1895-1903, Haematologica, Pavia, Italy, C1

journal article

Systematic investigation of oxygen and growth factors in clinically valid ex vivo expansion of cord blood CD34+ hematopoietic progenitor cells

M Tursky, F Collier, A Ward, M Kirkland

(2012), Vol. 14, pp. 679-685, Cytotherapy, Oxford, England, C1

journal article
2011

Groundwater pre-treatment prevents the onset of chronic ulcerative dermatopathy in juvenile Murray cod, Maccullochella peelii peelii (Mitchell)

A Schultz, S Shigdar, P Jones, A Ward, T Toop

(2011), Vol. 312, pp. 19-25, Aquaculture, Amsterdam, Netherlands, C1

journal article

Suppressor of cytokine signaling 1 regulates embryonic myelopoiesis independently of its effects on T cell development

L O'Sullivan, S Noor, M Trengove, R Lewis, C Liongue, N Sprigg, S Nicholson, A Ward

(2011), Vol. 186, pp. 4751-4761, Journal of immunology, Bethesda, Md., C1

journal article

Clinical applications of aptamers and nucleic acid therapeutics in haematological malignancies

S Shigdar, A Ward, A De, C Yang, M Wei, W Duan

(2011), Vol. 155, pp. 3-13, British journal of haematology, Oxford, U. K., C1

journal article

Shooting the messenger : targeting signal transduction pathways in leukemia and related disorders

S Noor, R Bell, A Ward

(2011), Vol. 78, pp. 33-44, Critical reviews in oncology / hematology, Clare, Ireland, C1

journal article

The Ikaros gene family : transcriptional regulators of hematopoiesis and immunity

L John, A Ward

(2011), Vol. 48, pp. 1272-1278, Molecular immunology, Oxford, U. K., C1

journal article

Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile

A Latifi, K Abubaker, N Castrechini, A Ward, C Liongue, F Dobill, J Kumar, E Thompson, M Quinn, J Findlay, N Ahmed

(2011), Vol. 112, pp. 2850-2864, Journal of cellular biochemistry, Hoboken N.J., C1

journal article

Origins of adaptive immunity

C Liongue, L John, A Ward

(2011), Vol. 31, pp. 61-71, Critical reviews in immunology, Redding, Conn., C1

journal article
2009

Suppressors of cytokine signaling : functions in normal biology and roles in disease

A Ward, A Barry, L O'Sullivan

(2009), pp. 10-23, Jak-stat pathway in disease, Austin, Tex., B1

book chapter

Multiple mini-interview : how long is long enough?

M Dodson, B Crotty, D Prideaux, R Carne, A Ward, E de Leeuw

(2009), Vol. 43, pp. 168-174, Medical education, Oxford, England, C1

journal article

Genetic and molecular diagnosis of severe congenital neutropenia

A Ward, D Dale

(2009), Vol. 16, pp. 9-13, Current opinion in hematology, Philadelphia, Pa., C1

journal article

Cytochemical characterisation of the leucocytes and thrombocytes from murray cod (Maccullochella peelii peelii, Mitchell)

S Shigdar, A Harford, A Ward

(2009), Vol. 26, pp. 731-736, Fish and shellfish immunology, Amsterdam, The Netherlands, C1

journal article

Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas

M Colomiere, A Ward, C Riley, M Trenerry, D Cameron-Smith, J Findlay, L Ackland, N Ahmed

(2009), Vol. 100, pp. 134-144, British journal of cancer, London, England, C1

journal article

Granulocyte colony-stimulating factor receptor: stimulating granulopoiesis and much more

C Liongue, C Wright, A Russell, A Ward

(2009), Vol. 41, pp. 2372-2375, International journal of biochemistry and cell biology, Amsterdam, The Netherlands, C1

journal article

A novel zebrafish jak2a V581F model shared features of human JAK2 V617F polycythemia vera

A Ma, A Fan, A Ward, C Liongue, R Lewis, S Cheng, P Chan, S Yip, R Liang, A Leung

(2009), Vol. 37, pp. 1379-1386, Experimental hematology, Amsterdam, The Netherlands, C1

journal article

Altering presenilin gene activity in zebrafish embryos causes changes in expression of genes with potential involvement in alzheimer's disease pathogenesis

M Newman, B Tucker, S Nornes, A Ward, M Lardelli

(2009), Vol. 16, pp. 133-147, Journal of alzheimer's disease, Amsterdam, The Netherlands, C1-1

journal article

Zebrafish granulocyte colony-stimulatingZebrafish granulocyte colony-stimulating factor receptor signaling promotes myelopoiesis and myeloid cell migration

C Liongue, C Hall, B O'Connell, P Crosier, A Ward

(2009), Vol. 113, pp. 2535-2546, Blood, Washington, D.C., C1

journal article

Evolution of the ikaros gene family : implications for the origins of adaptive immunity

L John, S Yoong, A Ward

(2009), Vol. 182, pp. 4792-4799, The journal of immunology, Bethesda, Md., C1

journal article
2008

Functional interaction between mutations in the granulocyte colony-stimulating factor receptor in severe congenital neutropenia

A Ward, J Gits, F Majeed, A Aprikyan, R Lewis, L O`Sullivan, M Freedman, S Shigdar, I Touw, D Dale, Y Dror

(2008), Vol. 142, pp. 653-656, British journal of haematology, Oxford, England, C1

journal article

Exercise-induced activation of STAT3 signaling is increased with age

M Trenerry, K Carey, A Ward, M Farnfield, D Cameron-Smith

(2008), Vol. 11, pp. 717-724, Rejuvenation research, New Rochelle, N.Y., C1

journal article

Stat5 as a diagnostic marker for leukemia

R Lewis, A Ward

(2008), Vol. 8, pp. 73-82, Expert review of molecular diagnostics, London, England, C1

journal article
2007

Evolution of class I cytokine receptors

C Liongue, A Ward

(2007), Vol. 7, pp. 1-15, BMC evolutionary biology, London, England, C1

journal article

From transcriptome to biological function: environmental stress in an ectothermic vertebrate, the coral reef fish Pomacentrus moluccensis

K Kassahn, R Crozier, A Ward, G Stone, M Caley

(2007), Vol. 8, pp. 1-16, BMC Genomics, London, England, C1

journal article

The role of jak2a in zebrafish hematopoiesis

A Ma, A Ward, R Liang, A Leung

(2007), Vol. 110, pp. 1824-1830, Blood, Washington, D.C., C1

journal article

Heterologous microarray experiments used to identify the early gene response to heat stress in a coral reef fish

K Kassahn, M Caley, A Ward, A Connolly, G Stone, R Crozier

(2007), Vol. 16, pp. 1749-1763, Molecular ecology, Oxford, England, C1

journal article

Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease

L O`Sullivan, C Liongue, R Lewis, S Stephenson, A Ward

(2007), Vol. 44, pp. 2497-2506, Molecular immunology, Oxford, England, C1

journal article

Blood cells of Murray cod maccullochella peelii peelii (Mitchell)

S Shigdar, D Cook, P Jones, A Harford, A Ward

(2007), Vol. 70, pp. 973-980, Journal of fish biology, Oxford, England, C1

journal article

The role of the granulocyte colony-stimulating factor receptor (G-CSF-R) in disease

A Ward

(2007), Vol. 12, pp. 608-618, Frontiers in bioscience, Tampa, Florida, C1

journal article

Characterization of the zebrafish matrix metalloproteinase 9 gene and its developmental expression pattern

S Yoong, B O'Connell, A Soanes, M Crowhurst, G Lieschke, A Ward

(2007), Vol. 7, pp. 39-46, Gene expression patterns, Amsterdam, The Netherlands, C1

journal article

The myeloproliferative disorder-associated JAK2 V617F mutant escapes negative regulation by suppressor of cytokine signaling 3

M Hookham, J Elliott, Y Suessmuth, J Staerk, A Ward, W Vainchenker, M Percy, M McMullin, S Constantinescu, J Johnston

(2007), Vol. 109, pp. 4924-4929, Blood, Washington, D.C., Wash., C1

journal article

STAT3 signaling is activated in human skeletal muscle following acute resistance exercise

M Trenerry, K Carey, A Ward, D Cameron-Smith

(2007), Vol. 102, pp. 1483-1489, Journal of applied physiology, Bethesda, Md., C1

journal article
2006

Constitutive activation of zebrafish Stat5 expands hematopoietic cell populations in vivo

R Lewis, S Stephenson, A Ward

(2006), Vol. 34, pp. 179-187, Experimental hematology, New York, N.Y., C1

journal article

Multiple pathways contribute to the hyperproliferative responses from truncated granulocyte colony-stimulating factor receptors

J Gits, D van Leeuwen, H Carroll, I Touw, A Ward

(2006), Vol. 20, pp. 2111-2118, Leukemia, Houndmills, England, C1

journal article
2005

Hematopoietic perturbation in zebrafish expressing a tel-jak2a fusion

S Onnebo, M Condron, D McPhee, G Lieschke, A Ward

(2005), Vol. 33, pp. 182-188, Experimental hematology, Amsterdam , The Netherlands, C1

journal article

RBMX gene is essential for brain development in Zebrafish

E Tsend-Ayush, L O`Sullivan, F Grutzner, S Onnebo, R Lewis, M Delbridge, J Marshall Graves, A Ward

(2005), Vol. 234, pp. 682-688, Developmental dynamics, Hoboken, N.J., C1

journal article
2004

Conservation, duplication and divergence of the zebrafish stat5 genes

R Lewis, A Ward

(2004), Vol. 338, pp. 65-74, Gene, Amsterdam, The Netherlands, C1

journal article

Harnessing zebrafish for the study of white blood cell development and its perturbation

S Onnebo, S Yoong, A Ward

(2004), Vol. 32, pp. 789-796, Experimental hematology, Amsterdam, The Netherlands, C1

journal article

Receptor activation and 2 distinct COOH- terminal motifs control G-CSF receptor distribution and internalization kinetics.

L Aarts, O Roovers, A Ward, I Touw

(2004), Vol. 103, pp. 571-579, Blood, Washington, D.C., C1-1

journal article
2003

The zebrafish spil promoter drives myeloid-specific expression in stable transgenic fish

A Ward, D McPhee, M Condron, S Varma, S Cody, S Onnebo, B Paw, L Zon, G Lieschke

(2003), Vol. 102, pp. 3238-3240, Blood, Washington, D.C., Wash., C1

journal article

Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells

M Hermans, G van de Geijn, C Antonissen, J Gits, D van Leeuwen, A Ward, I Touw

(2003), Vol. 101, pp. 2584-2590, Blood, Washington, D.C., C1

journal article
2002

Stats and hematopoiesis

A Ward

(2002), pp. 78-91, Jak-stat pathway in hematopoiesis and disease, Georgetown, Tex., B1

book chapter

The zebrafish as a model system for human disease

A Ward, G Lieschke

(2002), Vol. 7, Frontiers in bioscience, Tampa, Fla., C1-1

journal article

Specificity and affinity motifs for Grb2 SH2-ligand interactions

H Kessels, A Ward, T Schumacher

(2002), Vol. 99, pp. 8524-8529, Proceedings of the National Academy of Sciences, Washington, D.C., C1-1

journal article

Tyrosine residues of the granulocyte colony-stimulating factor transmit proliferation and differentiation signals in murine bone marrow cells

S Arkbarzadeh, A Ward, D McPhee, W Alexander, G Lieschke, J Layton

(2002), Vol. 99, pp. 879-887, Blood, Washington D.C., C1-1

journal article

G-CSF: function and modes of action (Review)

S Basu, A Dunn, A Ward

(2002), Vol. 10, pp. 3-10, International journal of molecular medicine, Athens, Greece, C1-1

journal article

Zebrafish SPI-1 marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning.

G Lieschke, A Oates, B Paw, M Thompson, N Hall, A Ward, R Ho, L Zon, J Layton

(2002), Vol. 246, pp. 274-295, Developmental biology, Amsterdam, The Netherlands, C1-1

journal article
2001

Proteomic analysis of macrophage differentiation

X Csar, N Wilson, K McMahon, D Marks, T Beecroft, A Ward, G Whitty, V Kanangasundarum, J Hamilton

(2001), Vol. 276, pp. 26211-26217, Journal of Biological Chemistry, United States, C1-1

journal article

C/EBPÁ and G-CSF receptor signals cooperate to induce the myeloperoxidase and neutrophil elastase genes

W Wang, X Wang, A Ward, I Touw, A Friedman

(2001), Vol. 15, pp. 779-786, Leukemia, London, England, C1-1

journal article

Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish.

G Lieschke, A Oates, M Crowhurst, A Ward, J Layton

(2001), Vol. 98, pp. 3087-3096, Blood, Washington, D.C., Wash., C1-1

journal article

Copper/zinc superoxide dismutase is phosphorylated and modulated specifically by granulocyte-colony stimulating factor in myeloid cells.

X Csar, N Wilson, P Strike, L Sparrow, K McMahon, A Ward, J Hamilton

(2001), Vol. 1, pp. 435-443, Proteomics, Weinheim, Germany, C1-1

journal article

Somatostatin modulates G-CSF-induced but not interleukin-3-induced proliferative responses in myeloid 32D cells via activation of somatostatin receptor subtype 2

S Oomen, A Ward, L Hofland, S Lamberts, B Löwenberg, I Touw

(2001), Vol. 2, pp. 322-329, Hematology journal: the official journal of the European haematology association / EHA, London, England, C1-1

journal article
2000

Signaling mechanisms of cytokine receptors and their perturbances in disease

I Touw, J De Koning, A Ward, M Hermans

(2000), Vol. 160, pp. 1-9, Molecular and celllular endocrinology, Amsterdam, The Netherlands, C1-1

journal article

The Jak-Stat pathway in normal and perturbed hematopoiesis

A Ward, I Touw, A Yoshimura

(2000), Vol. 95, pp. 19-29, Blood, Washington, D.C., C1-1

journal article

Combined corticosteroid/granulocyte colony-stimulating factor (G-CSF) therapy in the treatment of severe congenital neutropenia unresponsive to G-CSF: activated glucocorticoid receptors synergize with G-CSF signals

Y Dror, A Ward, I Touw, M Freedman

(2000), Vol. 28, pp. 1381-1389, Experimental hematology, Amsterdam, The Netherlands, C1-1

journal article

Regulation of granulopoiesis by transcription factors and cytokine signals

A Ward, D Loeb, A Soede-Bobok, I Touw, A Friedman

(2000), Vol. 14, pp. 973-990, Leukemia, London, Eng., C1-1

journal article

STAT3-mediated differentiation and survival and of myeloid cells in response to granulocyte colony-stimulating factor: role for the cyclin-dependent kinase inhibitor p27(Kip1)

J de Koning, A Soede-Bobok, A Ward, A Schelen, C Antonissen, D van Leeuwen, B Löwenberg, I Touw

(2000), Vol. 19, pp. 3290-3298, Oncogene, London, Eng., C1-1

journal article

The SH2 domain-containing protein tyrosine phosphatase SHP-1 is induced by granulocyte colony-stimulating factor (G-CSF) and modulates signaling from the G-CSF receptor

A Ward, S Oomen, L Smith, J Gits, D van Leeuwen, A Soede-Bobok, C Erpelinck-Verschueren, T Yi, I Touw

(2000), Vol. 14, pp. 1284-1291, Leukemia, London, Eng., C1-1

journal article
1999

Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment

A Ward, Y van Aesch, J Gits, A Schelen, J de Koning, D van Leeuwen, M Freedman, I Touw

(1999), Vol. 190, pp. 497-507, The Journal of Experimental Medicine, New York, N.Y., C1-1

journal article

Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells

A Ward, L Smith, J de Koning, Y van Aesch, I Touw

(1999), Vol. 274, pp. 14956-14962, Journal of biological chemistry, Bethesda, Md., C1-1

journal article

Protein phosphatase 2A is expressed in response to colony-stimulating factor 1 in macrophages and is required for cell cycle progression independently of extracellular signal-regulated protein kinase activity

N Wilson, S Moss, X Csar, A Ward, J Hamilton

(1999), Vol. 339, pp. 517-524, Biochemical journal, London, Eng., C1-1

journal article

Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene

M Hermans, C Antonissen, A Ward, A Mayen, R Ploemacher, I Touw

(1999), Vol. 189, pp. 683-692, Journal of Experimental Medicine, New York, N.Y., C1-1

journal article

Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia

A Ward, Y van Aesch, A Schelen, I Touw

(1999), Vol. 93, pp. 447-458, Blood, Washington, D.C., C1-1

journal article

Tyrosine-dependent and -independent mechanisms of STAT3 activation by the human granulocyte colony-stimulating factor (G-CSF) receptor are differentially utilized depending on G-CSF concentration

A Ward, M Hermans, L Smith, Y van Aesch, A Schelen, C Antonissen, I Touw

(1999), Vol. 93, pp. 113-124, Blood, Washington, D.C., C1-1

journal article
1998

Direct binding of Shc, Grb2, SHP-2 and p40 to the murine granulocyte colony-stimulating factor receptor

A Ward, J Monkhouse, J Hamilton, X Csar

(1998), Vol. 1448, pp. 70-76, Biochimica et biophysica acta, Amsterdam, The Netherlands, C1-1

journal article

Perturbed granulopoiesis in mice with a targeted mutation in the granulocyte colony-stimulating factor receptor gene associated with severe chronic neutropenia

M Hermans, A Ward, C Antonissen, A Karis, B Löwenberg, I Touw

(1998), Vol. 92, pp. 32-39, Blood, Washington, D.C., C1-1

journal article

The Src-like tyrosine kinase Hck is activated by granulocyte colony-stimulating factor (G-CSF) and docks to the activated G-CSF receptor

A Ward, J Monkhouse, X Csar, I Touw, P Bello

(1998), Vol. 251, pp. 117-123, Biochemical and biophysical research communications, Amsterdam, The Netherlands, C1-1

journal article

cAMP enhances CSF-1-induced ERK activity and c-fos mRNA expression via a MEK-dependent and Ras-independent mechanism in macrophages

N Wilson, A Jaworowski, A Ward, J Hamilton

(1998), Vol. 244, pp. 475-480, Biochemical and biophysical research communications, Amsterdam, The Netherlands, C1-1

journal article
1997

Changes in the hemagglutinin molecule of influenza type A (H3N2) virus associated with increased virulence for mice

C Hartley, P Reading, A Ward, E Anders

(1997), Vol. 142, pp. 75-88, Archives of virology, Berlin, Germany, C1-1

journal article

cAMP suppresses p21ras and Raf-1 responses but not the Erk-1 response to granulocyte-colony-stimulating factor: possible Raf-1-independent activation of Erk-1

X Csar, A Ward, B Hoffmann, G Guy, J Hamilton

(1997), Vol. 322, pp. 79-87, Biochemical journal, London, Eng., C1-1

journal article

Identification of phosphoproteins specific to granulocyte colony-stimulating factor-mediated signaling using 2D-SDS-PAGE

X Csar, A Ward, B Hoffmann, G Guy, J Hamilton

(1997), Vol. 17, pp. 77-86, Journal of interferon and cytokine research, New Rochelle, N.Y., C1-1

journal article
1995

Specific changes in the M1 protein during adaptation of influenza virus to mouse

A Ward

(1995), Vol. 140, pp. 383-389, Archives of virology, Vienna, Austria, C1-1

journal article

Expression and analysis of the NS2 protein of influenza A virus

A Ward, L Castelli, A Lucantoni, J White, A Azad, I Macreadie

(1995), Vol. 140, pp. 2067-2073, Archives of virology, Vienna, Austria, C1-1

journal article

A domain of human immunodeficiency virus type 1 Vpr containing repeated H(S/F)RIG amino acid motifs causes cell growth arrest and structural defects

I Macreadie, L Castelli, D Hewish, A Kirkpatrick, A Ward, A Azad

(1995), Vol. 92, pp. 2770-2774, Proceedings of the National Academy of Sciences, Washington, D.C., C1-1

journal article
1994

Characterisation of the urease-encoding gene complex of Yersinia enterocolitica

T de Koning-Ward, A Ward, R Robins-Browne

(1994), Vol. 145, pp. 25-32, Gene, Amsterdam, The Netherlands, C1-1

journal article

Expression and characterisation of the influenza A virus non-structural protein NS1 in yeast

A Ward, A Azad, I Macreadie

(1994), Vol. 138, pp. 299-314, Archives of Virology, Wien, Austria, C1-1

journal article

Vectors for Cu2+-inducible production of glutathione S-transferase-fusion proteins for single-step purification from yeast

A Ward, L Castelli, I Macreadie, A Azad

(1994), Vol. 10, pp. 441-449, Yeast, Chichester, Eng., C1-1

journal article
1993

Secretion of β-lactamase from K. lactis using pEPS1, a convenient episomal vector designed for the secretion of foreign proteins

I Macreadie, L Castelli, A Ward, M Stark, A Azad

(1993), Vol. 15, pp. 213-218, Biotechnology letters, Dordrecht, The Netherlands, C1-1

journal article

Expression of HIV-1 nef in yeast: the 27 kDa Nef protein is myristylated and fractionates with the nucleus

I Macreadie, A Ward, P Failla, A Azad, E Grgacic, D McPhee

(1993), Vol. 9, pp. 565-573, Yeast, Hoboken, N.J., C1-1

journal article

Funded Projects at Deakin

Australian Competitive Grants

Defining mechanisms underlying skeletal muscle development and muscular dystrophy

Dr Daniel Mcculloch, Dr Nicole Stupka, Prof Alister Ward

Financial Markets - Foundation for Children

  • 2012: $34,980
  • 2011: $71,230
  • 2010: $36,250

Identifying underlying causes of craniofacial defects in newborns

Prof Alister Ward, Dr Daniel Mcculloch, A/Prof Nicky Kilpatrick, Dr Mike Forrester

Financial Markets - Foundation for Children

  • 2016: $24,409
  • 2015: $59,364
  • 2014: $32,514

Other Public Sector Funding

Researcher of the year (teaching & learning) award

Prof Alister Ward, Prof Evelyne de Leeuw, Prof Brendan Crotty, Dr Karen D'Souza, Ms Sharyn Milnes

Smart Geelong Network Grant - Research

  • 2009: $4,545

Equipment Grant 2009

Prof Alister Ward

NHMRC - Equipment Grant (pre 2017)

  • 2009: $48,114

NHMRC Equipment Grant 2011 - MMR SRC

Prof Julian Mercer, Prof Alister Ward

NHMRC - Equipment Grant (pre 2017)

  • 2011: $9,897

Delivery of MIRNA Using Genetically Modified Influenza Virus

Prof John Stambas, Prof Alister Ward, Prof Ken Walder, Ms Yingju Xia

Victorian International Research Scholarships

  • 2014: $60,000

Characterising the role of interferons in low and highly pathogenic influenza virus infection in the chicken

Prof Alister Ward, Mr Andreas Rohringer

CSIRO

  • 2016: $7,000
  • 2015: $7,000
  • 2014: $7,000
  • 2013: $7,000

Anaerobic Bacterial Culture Cabinet

Prof Alister Ward

NHMRC - Equipment Grant (pre 2017)

  • 2013: $22,500

NHMRC Equipment Grant 2016

Prof Alister Ward

NHMRC - Equipment Grant (pre 2017)

  • 2016: $19,922

Neuropathogenesis of viral infections.

Prof Alister Ward

CSIRO

  • 2024: $28,855
  • 2023: $54,532
  • 2022: $46,588
  • 2021: $91,062
  • 2020: $135,794

Long term physical and psychological consequences of Covid-19 infection. A Comparitive Observational Study in Regional Victoria.

Prof Eugene Athan, Dr Darcie Cooper, Prof Peter Vuillermin, Dr Daniel O'Brien, Prof John Stambas, Prof Alister Ward, Prof Michael Berk, Prof Julie Pasco, A/Prof Alyssa Barry, Prof Soren Alexandersen

Department of Jobs, Precincts & Regions

  • 2021: $228,000

Genome editing innovation.

Prof Alister Ward, Dr Clifford Liongue

CSIRO

  • 2022: $40,000

Sperm Transfection Assisted Gene Editing (STAGE) in Zebrafish.

Dr Clifford Liongue, Prof Alister Ward

CSIRO

  • 2023: $77,000

Industry and Other Funding

Establishment of the First Medical School in Geelong

Prof Wei Duan, Prof Alister Ward, Prof Brendan Crotty

Geelong Community Foundation Grant - Research

  • 2007: $30,000

Impact of subterranean water on the physiology and health of Murray cod (Maccullochella peeli peeli)

Dr Paul Jones, Hon Prof Sena Desilva, Prof Giovanni Turchini, Prof Tes Toop, Prof Alister Ward

Aust & Pacific Science Foundation Grant - Research CAT3

  • 2009: $5,000
  • 2008: $2,000
  • 2007: $14,000
  • 2006: $7,000

Establishment of GTRAC

Prof Alister Ward

Geelong Community Foundation Grant - Research

  • 2010: $24,560
  • 2009: $22,920

CONTACT: Consortium for the evaluation of targeted cancer therapies

Prof Alister Ward, A/Prof Richard Bell

CONTACT Grant - Research - Contact Asia Pacific Inc

  • 2010: $88,554
  • 2009: $192,049

Deakin Cancer Research

Prof Alister Ward

ANZCT - Norman, Ann & Graeme Atkins Charitable Trust

  • 2012: $5,000

Automated gene expression quantification machine: qRT-PCR

Dr Yann Gibert, Prof Alister Ward

Collier Charitable Fund

  • 2014: $33,800

Improving Cancer Diagnostics By Using Chemical Flags - Cancer Research Scholarship

Prof Alister Ward, A/Prof Sarah Shigdar

Equity Trustees - Norman, Ann & Graeme Atkins Charitable Trust

  • 2017: $14,000
  • 2016: $14,000
  • 2015: $14,000

Research into the role of Proteins called cytokine receptors in ovarian cancer and the development of novel agents to suppress their effects

Prof Alister Ward, Prof Wei Duan, Dr Daniel Mcculloch

Equity Trustees - Norman, Ann & Graeme Atkins Charitable Trust

  • 2015: $12,500
  • 2014: $12,500
  • 2013: $12,500

Associate Professor of Infection Systems Epidemiology.

A/Prof Alyssa Barry, Prof Alister Ward

Burnet Institute

  • 2024: $26,864
  • 2023: $83,643
  • 2022: $78,940
  • 2021: $172,492

Other Funding Sources

Collaborative High Bio-Containment immunological Research Facility

Prof Alister Ward, Dr Linfa Wang, Prof John Stambas, Dr John Lowenthal, Prof Ralph Tripp, Prof Johnson Mak, Prof Bill Buttemer, Prof Tania De Koning-Ward

ARC LIEF - Linkage Infrastructure Equipment & Facilities Program, CSIRO Commonwealth Scientific and Industrial Research Organisation

  • 2012: $105,000
  • 2011: $100,000

ARC College - 2014 Nomination - Prof Alister Ward

Prof Alister Ward

ARC College of Experts

  • 2016: $13,904

Blue laser for BD FACS Canto II

Prof Alister Ward

NHMRC - Equipment Grant - Not R&D income countable (2017-current)

  • 2019: $10,457

Supervisions

Principal Supervisor
2024

Mohamed Sobah

Thesis entitled: Understanding the Role of STAT3 Proteins and its Negative Regulators in Cytokine Signaling

Doctor of Philosophy (Medicine), School of Medicine

Somayyeh Heidary

Thesis entitled: Function of STAT5 Protein During Development and Disease

Doctor of Philosophy (Medicine), School of Medicine

2023

Nagendra Prasad Awasthi

Thesis entitled: Investigating the Role of Non-Canonical STAT5 Protein Functions During Development

Doctor of Philosophy (Medicine), School of Medicine

2022

Tarka Bhatta

Thesis entitled: Detection and characterisation of animal influenza and other viruses

Doctor of Philosophy (Joint, Uni of Copenhagen), School of Medicine

2021

Wasan Abbood Hassoon Naser

Thesis entitled: Role of cytokine-inducible Src homology domain 2-containing protein in myelopoiesis and metabolic regulation

Doctor of Philosophy (Medicine), School of Medicine

2020

Sheena Bhanuprakash Raju

Thesis entitled: Factors involved in cardiogenesis

Doctor of Philosophy (Medicine), School of Medicine

Hao Fang

Thesis entitled: The role of IL-6 family signalling components in ovarian cancer

Doctor of Philosophy (Medicine), School of Medicine

2019

Tarannum Taznin

Thesis entitled: Investigating Cytokine Receptor Functions in Zebrafish.

Doctor of Philosophy (Medicine), School of Medicine

Farooq Lateef Jassim Almohaisen

Thesis entitled: Dissecting the function of B-Cell Lymphoma 6A (BCL6A) protein in zebrafish.

Doctor of Philosophy (Medicine), School of Medicine

2018

Saeed Mahmoudimeimand

Thesis entitled: Control of cytokine receptor signalling by CISH

Doctor of Philosophy (Medicine), School of Medicine

Faiza Basheer

Thesis entitled: Zebrafish as a genetic model for leukemia and other hematopoietic disorders

Doctor of Philosophy (Medicine), School of Medicine

2016

Andreas Rohringer

Thesis entitled: A study of the chicken IFN lambda system

Doctor of Philosophy (Medicine), School of Medicine

Robert Matthew Sertori

Thesis entitled: Investigating interleukin-2 receptor family signaling in zebrafish

Doctor of Philosophy (Medicine), School of Medicine

2015

Monique Trengove

Thesis entitled: Suppressor of cytokine signalling 4 and 5 in zebrafish development

Doctor of Philosophy (Medicine), School of Medicine

Carolyn Dancevic

Thesis entitled: Dissecting ADAMTS Proteoglycanase Biology in Development and Disease

Doctor of Philosophy (Medicine), School of Medicine

Brian Clarke

Thesis entitled: Expression of anti-viral shRNA molecules in transgenic zebrafish

Doctor of Philosophy (Medicine), School of Medicine

Parisa Rasighaemi

Thesis entitled: Dissecting the role of the ETV6 transcriptional regulator in development and disease

Doctor of Philosophy (Medicine), School of Medicine

2014

Janani Kumar

Thesis entitled: Aberrant Cytokine Signaling in Ovarian Cancer

Doctor of Philosophy (Medicine), School of Medicine

2013

Kate Goossens

Thesis entitled: Comparative analysis of type III interferon receptor and interferon-stimulated genes

Doctor of Philosophy (Medicine), School of Medicine

Michael James Dodson

Thesis entitled: The Multiple Mini-Interview (MMI) in medical student selection

Doctor of Philosophy (Medicine), School of Medicine

2011

Suzita Mohd Noor

Thesis entitled: Role of JAK2-Stats-C15 Pathway Components in Zebrafish Development

Doctor of Philosophy (Medicine), School of Medicine

2010

Liza Bernadine Raymond

Thesis entitled: The Ikaros Gene Family: Characterisation of the `Atypical' Pegasus

Doctor of Philosophy (Medicine), School of Medicine

2009

Sarah Louise Shigdar

Thesis entitled: Haematology of Murray Cod: Molecular and Cellular Analysis

Doctor of Philosophy (Medicine), School of Medicine

Clifford Liongue

Thesis entitled: Evolution of Class 1 Cytokine Receptor Signalling: Conservation of GCSFR

Doctor of Philosophy (Medicine), School of Medicine

2007

Rowena Lewis

Thesis entitled: Analysis of the stat5 Genes in Zebrafish

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2005

Sara Onnebo

Thesis entitled: Study of Myeloid Leukaemogenesis in Zebrafish

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

Executive Supervisor
2020

Vilasha Bulleeraz

Thesis entitled: Disruption of cytokine signalling in leukemia

Master of Philosophy (Medicine), School of Medicine

Associate Supervisor
2023

Jessie Pedrina

Thesis entitled: Investigating the role of ADAMTS proteoglycanases in influenza virus immunity

Doctor of Philosophy (Medicine), School of Medicine

2019

Avinash Soundararajan

Thesis entitled: Novel clinico-molecular insights into the role of bisphenol-A (BPA) in the etiology of diabetes

Doctor of Philosophy (Medicine), School of Medicine

2018

Prusothman Yoganantharajah

Thesis entitled: Zebrafish: Drug discovery, toxicity testing and chemical modulators of lipids

Doctor of Philosophy (Medicine), School of Medicine

John Desmond Molloy

Thesis entitled: A Population Based Investigation of Early Life Risk Factors in Relation to IgE-Mediated Food Allergy in Infants

Doctor of Philosophy (Medicine), School of Medicine

2017

Yingju Xia

Thesis entitled: Delivery of Immunomodulatory miRNAs Using Genetically Modified Influenza Viruses

Doctor of Philosophy (Medicine), School of Medicine

Christopher Kintakas

Thesis entitled: ADAMTS5 expression and function in myoblast fusion and muscle regeneration

Doctor of Philosophy (Medicine), School of Medicine

2016

Scott Chisholm

Thesis entitled: Characterisation of PTEX88, a component of the Plasmodium translocon

Doctor of Philosophy (Medicine), School of Medicine

Jasmina Luczo

Thesis entitled: Pathogenesis of avian influenza: role of the haemagglutinin cleavage site motif

Doctor of Philosophy (Medicine), School of Medicine

2015

Daniel Fraher

Thesis entitled: Chemical Modulators of Lipid Abundance and Bone Development

Doctor of Philosophy (Medicine), School of Medicine

Vengama Naidu Modepalli

Thesis entitled: The Marsupial: A unique model for understanding the regulation of lung development

Doctor of Philosophy (Medicine), School of Medicine

Ashalyn Watt

Thesis entitled: Innate immunity in the breast and the role of the milk peptidome

Doctor of Philosophy (Medicine), School of Medicine

Mohammed Jasim Mohammed Shallal

Thesis entitled: Recombinant Influenza virus as HIV vaccine vector

Doctor of Philosophy (Medicine), School of Medicine

2013

Craig Wright

Thesis entitled: ROLE AND REGULATION OF G-CSF AND ITS RECEPTOR IN MUSCLE

Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences

Jia Lin

Thesis entitled: A nanoliposome-based drug delivery system for cancer

Doctor of Philosophy (Medicine), School of Medicine

2012

Katherine Birrer

Thesis entitled: Silencing Host Genes Using RNAi to Impact Virus Growth in vitro Methods for reducing cotton wax.

MAppSc (Medicine) (High cost), School of Medicine

2011

Keith Niven

Thesis entitled: Mitochondrial Division in Dictyostelium Discoideum

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences

2009

Lynda Anne Kearney

Thesis entitled: Dissecting the Role of socs Proteins using Zebrafish

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences