Prof Andrew Sinclair

STAFF PROFILE

Position

Emeritus Professor

Faculty

Faculty of Health

Department

Office of Faculty of Health

Campus

Melbourne Burwood Campus

Contact

Publications

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2018

How does high DHA fish oil affect health? A systematic review of evidence

S Ghasemi Fard, F Wang, A Sinclair, G Elliott, G Turchini

(2018), pp. 1-44, Critical reviews in food science and nutrition, Abingdon, Eng., C1

journal
2017

Nitrate and hydrogen peroxide generated in water by electrical discharges stimulate wheat seedling growth

M Maniruzzaman, A Sinclair, D Cahill, X Wang, X Dai

(2017), Vol. 37, pp. 1393-1404, Plasma chemistry and plasma processing, New York, N.Y., C1

journal

Differential effects of EPA, DPA and DHA on cardio-metabolic risk factors in high-fat diet fed mice

X-F Guo, A Sinclair, G Kaur, D Li

(2017), pp. 1-9, Prostaglandins, leukotrienes and essential fatty acids, Amsterdam, The Netherlands, C1

journal
2016

Short update on docosapentaenoic acid: a bioactive long-chain n-3 fatty acid

G Kaur, X-F Guo, A Sinclair

(2016), Vol. 19, pp. 88-91, Current opinion in clinical nutrition and metabolic care, Philadelphia, Pa., C1

journal

Zebrafish embryonic lipidomic analysis reveals that the yolk cell as metabolically active in processing lipid

D Fraher, A Sanigorski, N Mellett, P Meikle, A Sinclair, Y Gibert

(2016), Vol. 14, pp. 1317-1329, Cell reports, Amsterdam, The Netherlands, C1

journal

Anti-inflammatory activity and mechanisms of a lipid extract from hard-shelled mussel (mytilus coruscus) in mice with dextran sulphate sodium-induced colitis

F Wang, Y Fu, W Cai, A Sinclair, D Li

(2016), Vol. 23, pp. 389-399, Journal of functional foods, London, Eng., C1

journal

Divergent shifts in lipid mediator profile following supplementation with n-3 docosapentaenoic acid and eicosapentaenoic acid

J Markworth, G Kaur, E Miller, A Larsen, A Sinclair, K Maddipati, D Cameron-Smith

(2016), Vol. 30, pp. 3714-3725, FASEB journal, Bethesda, M.D., C1

journal

Australian and New Zealand fish oil products in 2016 meet label omega-3 claims and are not oxidized

P Nichols, L Dogan, A Sinclair

(2016), Vol. 8, pp. 1-9, Nutrients, Basel, Switzerland, C1

journal
2015

Dietary sources, current intakes, and nutritional role of omega-3 docosapentaenoic acid.

O Byelashov, A Sinclair, G Kaur

(2015), Vol. 27, pp. 79-82, Lipid technology, London, Eng., C1

journal

Postprandial responses to lipid and carbohydrate ingestion in repeated subcutaneous adipose tissue biopsies in healthy adults

A Dordevic, F Pendergast, H Morgan, S Villas-Boas, M Caldow, A Larsen, A Sinclair, D Cameron-Smith

(2015), Vol. 7, pp. 5347-5361, Nutrients, Basel, Switzerland, C1-1

journal

What is the most effective way of increasing the bioavailability of dietary long chain omega-3 fatty acids-daily vs. weekly administration of fish oil?

S Ghasemifard, A Sinclair, G Kaur, P Lewandowski, G Turchini

(2015), Vol. 7, pp. 5628-5645, Nutrients, Basel, Switzerland, C1

journal

Postprandial plasma phospholipids in men are influenced by the source of dietary fat

P Meikle, C Barlow, N Mellett, P Mundra, M Bonham, A Larsen, D Cameron-Smith, A Sinclair, P Nestel, G Wong

(2015), Vol. 145, pp. 2012-2018, Journal of nutrition, Rockville, Md, C1

journal

Metabolic fate (absorption, ?-oxidation and deposition) of long-chain n-3 fatty acids is affected by sex and by the oil source (krill oil or fish oil) in the rat

S Ghasemi Fard, K Hermon, G Turchini, A Sinclair

(2015), Vol. 114, pp. 684-692, British journal of nutrition, Cambridge, Eng, C1

journal

Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial

A Pipingas, A Sinclair, K Croft, A Januszewski, A Jenkins, T Mori, R Cockerell, N Grima, C Stough, A Scholey, S Myers, A Sali, M Pase

(2015), Vol. 19, pp. 949-957, Journal of functional foods, Amsterdam, The Netherlands, C1

journal
2014

Comparison of the bioavailability of docosapentaenoic acid (DPA, 22:5n-3) and eicosapentaenoic acid (EPA, 20:5n-3) in the rat

F Ghasemi, K Linderborg, G Turchini, A Sinclair

(2014), Vol. 90, pp. 23-26, Prostaglandins leukotrienes and essential fatty acids, Amsterdam, The Netherlands, C1

journal

Rapid development of non-alcoholic steatohepatitis in Psammomys obesus (Israeli Sand Rat)

B Spolding, T Connor, C Wittmer, L Abreu, A Kaspi, M Ziemann, G Kaur, A Cooper, S Morrison, S Lee, A Sinclair, Y Gibert, J Trevaskis, J Roth, A El-Osta, R Standish, K Walder

(2014), Vol. 9, pp. 1-7, PLoS one, San Francisco, Calif., C1

journal

Fabrication of boron nitride nanotube-gold nanoparticle hybrids using pulsed plasma in liquid

S Ponraj, Z Chen, L Li, J Shankaranarayanan, G Rajmohan, J du Plessis, A Sinclair, Y Chen, X Wang, J Kanwar, X Dai

(2014), Vol. 30, pp. 10712-10720, Langmuir, Washington, DC, C1

journal

Dietary repletion with ?3 fatty acid or with COX inhibition reverses cognitive effects in F3 ?3 fatty-acid-deficient mice.

A Hafandi, D Begg, S Premaratna, A Sinclair, M Jois, R Weisinger

(2014), Vol. 64, pp. 106-109, Comparative Medicine (Memphis), Memphis, TN, C1

journal

Pancreatic lipase selectively hydrolyses DPA over EPA and DHA due to location of double bonds in the fatty acid rather than regioselectivity

T Akanbi, A Sinclair, C Barrow

(2014), Vol. 160, pp. 61-66, Food chemistry, Amsterdam, The Netherlands, C1

journal

Effects of ingesting low glycemic index carbohydrate food for the sahur meal on subjective, metabolic and physiological responses, and endurance performance in Ramadan fasted men

W Png, K Bhaskaran, A Sinclair, A Aziz

(2014), Vol. 65, pp. 629-636, International journal of food sciences and nutrition, London, England, C1

journal

Muscle p70S6K phosphorylation in response to soy and dairy rich meals in middle aged men with metabolic syndrome: a randomised crossover trial

P Gran, A Larsen, M Bonham, A Dordevic, T Rupasinghe, C Silva, A Nahid, D Tull, A Sinclair, C Mitchell, D Cameron-Smith

(2014), Vol. 11, pp. 1-14, Nutrition and metabolism, England, C1

journal

Randomized controlled trial examining the effects of fish oil and multivitamin supplementation on the incorporation of n-3 and n-6 fatty acids into red blood cells

A Pipingas, R Cockerell, N Grima, A Sinclair, C Stough, A Scholey, S Myers, K Croft, A Sali, M Pase

(2014), Vol. 6, pp. 1956-1970, Nutrients, Basel, Switzerland, C1

journal

Omega-3 long chain fatty acid "bioavailability" : a review of evidence and methodological considerations

S Ghasemifard, G Turchini, A Sinclair

(2014), Vol. 56C, pp. 92-108, Progress in lipid research, Amsterdam, The Netherlands, C1

journal
2013

A short-term n-3 DPA supplementation study in humans

E Miller, G Kaur, A Larsen, S Loh, K Linderborg, H Weisinger, G Turchini, D Cameron-Smith, A Sinclair

(2013), Vol. 52, pp. 895-904, European journal of nutrition, Heidelberg, Germany, C1

journal

Orally administered [14C]DPA and [14C]DHA are metabolised differently to [14C]EPA in rats

G Kaur, J Molero, H Weisinger, A Sinclair

(2013), Vol. 109, pp. 441-448, British journal of nutrition, Cambridge, England, C1

journal

Assessing the impact of diabetes on the quality of life of older adults living in a care home : validation of the ADDQoL senior

J Speight, A Sinclair, J Browne, A Woodcock, C Bradley

(2013), Vol. 30, pp. 74-80, Diabetic Medicine, Chichester, England, C1

journal

Lipidomic profiling of chylomicron triacylglycerols in response to high fat meals

M Bonham, K Linderborg, A Dordevic, A Larsen, K Nguo, J Weir, P Gran, M Luotonen, P Meikle, D Cameron-Smith, H Kallio, A Sinclair

(2013), Vol. 48, pp. 39-50, Lipids, Dordrecht, The Netherlands, C1

journal

Dietary phytosterols modify the sterols and fatty acid profile in a tissue-specific pattern

R Alhazzaa, J Oen, A Sinclair

(2013), Vol. 5, pp. 829-837, Journal of functional foods, Amsterdam, The Netherlands, C1

journal

Targeted dietary micronutrient fortification modulates n-3 LC-PUFA pathway activity in rainbow trout (Oncorhynchus mykiss)

M Lewis, N Hamid, R Alhazzaa, K Hermon, J Donald, A Sinclair, G Turchini

(2013), Vol. 412-413, pp. 215-222, Aquaculture, Amsterdam, The Netherlands, C1

journal

Comparative actions of omega-3 fatty acids on in-vitro lipid droplet formation

E Barber, A Sinclair, D Cameron-Smith

(2013), Vol. 89, pp. 359-366, Prostaglandins Leukotrienes and Essential Fatty Acids, London, UK, C1

journal

Postprandial metabolism of docosapentaenoic acid (DPA, 22:5n-3) and eicosapentaenoic acid (EPA, 20:5n-3) in humans

K Linderborg, G Kaur, E Miller, P Meikle, A Larsen, J Weir, A Nuora, C Barlow, H Kallio, D Cameron-Smith, A Sinclair

(2013), Vol. 88, pp. 313-319, Prostaglandins Leukotrienes and Essential Fatty Acids, London, UK, C1

journal

Human inflammatory and resolving lipid mediator responses to resistance exercise and ibuprofen treatment

J Markworth, L Vella, B Lingard, D Tull, T Rupasinghe, A Sinclair, K Maddipati, D Cameron-Smith

(2013), Vol. 305, American journal of physiology - regulatory integrative and comparative physiology, Bethesda, Maryland, C1

journal

Bioconversion of ?-Linolenic Acid into n-3 Long-Chain polyunsaturated fatty acid in hepatocytes and ad hoc cell culture optimisation

R Alhazzaa, A Sinclair, G Turchini

(2013), Vol. 8, pp. 1-10, PLoS ONE, San Francisco, Calif., C1

journal
2012

Gender-specific inhibition of platelet aggregation following omega-3 fatty acid supplementation

M Phang, A Sinclair, L Lincz, M Garg

(2012), Vol. 22, pp. 109-114, Nutrition, metabolism & cardiovascular diseases, Napoli, Italy, C1

journal

The inclusion of 'then-test' questions in post-test questionnaires alters post-test responses: a randomized study of bias in health program evaluation

S Nolte, G Elsworth, A Sinclair, R Osborne

(2012), Vol. 21, pp. 487-494, Quality of life research, Dordrecht, The Netherlands, C1

journal

Effects of zinc and DHA on the epigenetic regulation of human neuronal cells

N Sadli, M Ackland, D De Mel, A Sinclair, C Suphioglu

(2012), Vol. 29, pp. 87-98, Cellular physiology and biochemistry, Basel, Switzerland, C1

journal

Jumping on the omega-3 bandwagon : distinguishing the role of long-chain and short-chain omega-3 fatty acids

G Turchini, P Nichols, C Barrow, A Sinclair

(2012), Vol. 52, pp. 795-803, Critical reviews in food science and nutrition, Philadelphia, Pa., C1

journal

Thirst deficits in aged rates are reversed by dietary omega-3 fatty acid supplementation

D Begg, A Sinclair, R Weisinger

(2012), Vol. 33, pp. 2422-2430, Neurobiology of aging, Philadelphia, Pa., C1

journal

Hypothalamic gene expression in w-3 PUFA-deficient male rats before, and following, development of hypertension

D Begg, L Puskas, K Kitajka, D Menesi, A Allen, D Li, M Mathai, J Shi, A Sinclair, R Weisinger

(2012), Vol. 35, pp. 381-387, Hypertension research, London, England, C1

journal

Reductions in water and sodium intake by aged male and female rats

D Begg, A Sinclair, R Weisinger

(2012), Vol. 32, pp. 865-872, Nutrition research, New York, N.Y., C1-1

journal
2011

Docosapentaenoic acid (22:5n-3) : a review of its biological effects

G Kaur, D Cameron-Smith, M Garg, A Sinclair

(2011), Vol. 50, pp. 28-34, Progress in lipid research, Amsterdam, The Netherlands, C1

journal

Transforming salmonid aquaculture from a consumer to a producer of long chain omega-3 fatty acids

G Turchini, D Francis, R Keast, A Sinclair

(2011), Vol. 124, pp. 609-614, Food chemistry, Amsterdam, The Netherlands, C1

journal

The role of reducing intakes of saturated fat in the prevention of cardiovascular disease : where does the evidence stand in 2010?

A Astrup, J Dyerberg, P Elwood, K Hermansen, F Hu, M Jakobsen, F Kok, R Krauss, J Lecerf, P LeGrand, P Nestel, U Riserus, T Sanders, A Sinclair, S Stender, T Tholstrup, W Willett

(2011), Vol. 93, pp. 684-688, American journal of clinical nutrition, Bethesda, Md., C1

journal

Docosapentaenoic acid (22:5n-3) down-regulates the expression of genes involved in fat synthesis in liver cells

G Kaur, A Sinclair, D Cameron-Smith, D Barr, J Molero-Navajas, N Konstantopoulos

(2011), Vol. 85, pp. 155-161, Prostaglandins, leukotrienes and essential fatty acids, Kidlington, U. K., C1

journal

Comparison of lipid content and fatty acid composition in the edible meat of wild and cultured freshwater and marine fish and shrimps from China

G Li, A Sinclair, D Li

(2011), Vol. 59, pp. 1871-1881, Journal of agricultural and food chemistry, Washington, D. C., C1

journal

Effect of zinc and DHA on expression levels and post-translational modifications of histones H3 and H4 in human neuronal cells

N Sadli, N Ahmed, M Ackland, A Sinclair, C Barrow, C Suphioglu

(2011), pp. 141-164, Neurodegenerative diseases - processes, prevention, protection and monitoring, Rijecka, Croatia, B1

chapter
2010

Short-term docosapentaenoic acid (22:5n-3) supplemtation increases tissue docosapentaenoic acid, DHA and EPA concentrations in rats

G Kaur, D Begg, D Barr, M Garg, D Cameron-Smith, A Sinclair

(2010), Vol. 103, pp. 32-37, British journal of nutrition, Cambridge, England, C1

journal

Dietary protein level interacts with ?-3 polyunsaturated fatty acid deficiency to induce hypertension

D Begg, A Sinclair, L Stahl, M Garg, M Jois, R Weisinger

(2010), Vol. 23, pp. 125-128, American journal of hypertension, London, England, C1

journal

Zinc and DHA have opposing effects on the expression levels of histones H3 and H4 in human neuronal cells

C Suphioglu, N Sadli, D Coonan, L Kumar, D De Mel, J Lesheim, A Sinclair, L Ackland

(2010), Vol. 103, pp. 344-351, British journal of nutrition, [Cambridge, England], C1

journal

The omega-3 fatty acid, DHA, decreases neuronal cell death in association with altered zinc transport

C Suphioglu, D De Mel, L Kumar, N Sadli, D Freestone, A Michalczyk, A Sinclair, M Ackland

(2010), Vol. 584, pp. 612-618, FEBS letters, Amsterdam, The Netherlands, C1

journal

Suppressive actions of eicosapentaenoic acid on lipid droplet formation in 3T3-L1 adipocytes

E Manickam, A Sinclair, D Cameron-Smith

(2010), Vol. 9, pp. 1-8, Lipids in health and disease, London, England, C1

journal

Hypertension induced by ?-3 polyunsaturated fatty acid deficiency is alleviated by ?-linolenic acid regardless of dietary source

D Begg, A Sinclair, L Stahl, S Premaratna, A Hafandi, M Jois, R Weisinger

(2010), Vol. 13, pp. 808-813, Hypertension research, London, England, C1

journal

Sodium appetite in adult rats following ?-3 polyunsaturated fatty acid deficiency in early development

R Weisinger, J Armitage, N Chen, D Begg, M Mathai, A Jayasooriya, A Sinclair, H Weisinger

(2010), Vol. 55, pp. 393-397, Appetite, Dordrecht, The Netherlands, C1

journal

Lipid composition of Australian pork cuts 2005/2006

A Sinclair, S Barone, T Stobaus, R Tume, S Beilken, W Muller, J Cunningham, J Barnes, H Greenfield

(2010), Vol. 121, pp. 672-681, Food chemistry, Amsterdam, The Netherlands, C1

journal
2009

Fatty acid composition in tissues of mice fed diets containing conjugated linolenic acid and conjugated linoleic acid

G Yuan, A Sinclair, H Sun, D Li

(2009), Vol. 16, pp. 148-163, Journal of food lipids, Oxford, England, C1

journal

?-Eleostearic acid is more effectively metabolized into conjugated linoleic acid than punicic acid in mice

G Yuan, A Sinclair, C Zhou, D Li

(2009), Vol. 89, pp. 1006-1011, Journal of the science of food and agriculture, Milton, Qld., C1

journal

Tests of measurement invariance failed to support the application of the 'then-test'

S Nolte, G Elsworth, A Sinclair, R Osborne

(2009), Vol. 62, pp. 1173-1180, Journal of clinical epidemiology, Amsterdam, The Netherlands, C1

journal

Polyunsaturated fats in meat from Merino, first- and second-cross sheep slaughtered as yearlings

E Ponnampalam, D Hopkins, K Butler, F Dunshea, A Sinclair, R Warner

(2009), Vol. 83, pp. 314-319, Meat science, Amsterdam, The Netherlands, C1

journal

Inhibition of platelet aggregation by omega-3 polyunsaturated fatty acids is gender specific - redefining platelet response to fish oils

M Phang, M Garg, A Sinclair

(2009), Vol. 81, pp. 35-40, Prostaglandins, leukotrienes and essential fatty acids, Amsterdam, The Netherlands, C1

journal

?-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans

J Brenna, N Salem Jr., A Sinclair, S Cunnane

(2009), Vol. 80, pp. 85-91, Prostaglandins, leukotrienes and essential fatty acids, Amsterdam, The Netherlands, C1

journal

The effect pf diary foods on CHD: a systematic review of prospective cohort studies

R Gibson, M Makrides, L Smithers, M Voevodin, A Sinclair

(2009), Vol. 2009, pp. 1-9, British journal of nutrition, Cambridge, England, C1

journal

Influence of heat on biological activity and concentration of oleocanthal : a natural anti-inflammatory agent in virgin olive oil

S Cicerale, X Conlan, N Barnett, A Sinclair, R Keast

(2009), Vol. 57, pp. 1326-1330, Journal of agricultural and food chemistry, Columbus, Oh., C1

journal

Green tea, black tea, and epigallocatechin modify body composition, improve glucose tolerance, and differentially alter metabolic gene expression in rats fed a high-fat diet

N Chen, R Bezzina, E Hinch, P Lewandowski, D Cameron-Smith, M Mathai, M Jois, A Sinclair, D Begg, J Wark, H Weisinger, R Weisinger

(2009), Vol. 29, pp. 784-793, Nutrition research, New York, N.Y., C1

journal

Fat intake and CNS functioning : ageing and disease

M Crawford, R Bazinet, A Sinclair

(2009), Vol. 55, pp. 202-228, Annals of nutrition and metabolism, Basel, Switzerland, C1

journal

Revisiting delta-6 desaturate regulation by C18 unsaturated fatty acids, depending on the nutritional status

J Skrzypski, S Bellenger, J Bellenger, A Sinclair, J Poisson, C Tessier, M Rialland, M Narce

(2009), Vol. 91, pp. 1443-1449, Biochimie, [Paris, France], C1

journal

Chemistry and health of olive oil phenolics

S Cicerale, X Conlan, A Sinclair, R Keast

(2009), Vol. 49, pp. 218-236, Critical reviews in food science and nutrition, Philadelphia, Pa., C1

journal

Incorporation and metabolism of punicic acid in healthy young humans

G Yuan, A Sinclair, C Xu, D Li

(2009), Vol. 53, pp. 1336-1342, Molecular nutrition and food research, Weinheim, Germany, C1

journal

Comparative effects of tuna oil and salmon oil on liver lipid metabolism and fatty acid concentrations in rats

T Huang, A Sinclair, L Shen, B Yang, D Li

(2009), Vol. 16, pp. 436-451, Journal of food lipids, Malden, Mass., C1

journal

A healthy diet consistent with Australian health recommendations is too expensive for welfare-dependant families

C Kettings, A Sinclair, M Voevodin

(2009), Vol. 33, pp. 566-572, Australian and New Zealand journal of public health, Richmond, Vic., C1

journal

Effects of conjugated linolenic acid and conjugated linoleic acid on lipid metabolism in mice

G Yuan, H Sun, A Sinclair, D Li

(2009), Vol. 111, pp. 537-545, European journal of lipid science and technology, Weinheim, Germany, C1-1

journal
2008

The role of omega-3 polyunsaturated fatty acids in food intake and energy homeostasis

R Weisinger, D Begg, L Stahl, H Weisinger, A Sinclair, M Jois

(2008), pp. 837-854, Fatty acids in foods and their health implications, Boca Raton, Fla., B1

chapter

Angiotensin converting enzyme inhibition from birth reduces body weight and body fat in Sprague-Dawley rats

H Weisinger, D Begg, G Egan, A Jayasooriya, F Lie, M Mathai, A Sinclair, J Wark, R Weisinger

(2008), Vol. 93, pp. 820-825, Physiology & behavior, Amsterdam, The Netherlands, C1

journal

The role of omega-3 fatty acids in mood disorders

L Stahl, D Begg, R Weisinger, A Sinclair

(2008), Vol. 9, pp. 57-64, Current opinion in investigational drugs, London, England, C1

journal

Selective reduction in body fat mass and plasma leptin induced by angiotensin-converting enzyme inhibition in rats

M Mathai, S Naik, A Sinclair, H Weisinger, R Weisinger

(2008), Vol. 32, pp. 1576-1584, International journal of obesity, London, England, C1

journal

Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance

A Jayasooriya, M Mathai, L Walker, D Begg, D Denton, D Cameron-Smith, G Egan, M McKinley, P Rodger, A Sinclair, J Wark, H Weisinger, M Jois, R Weisinger

(2008), Vol. 105, pp. 6531-6536, Proceedings of the National Academy of Sciences of the United States of America, Washington, D.C., C1

journal

The role of eicosanoids in the brain

D Tassoni, G Kaur, R Weisinger, A Sinclair

(2008), Vol. 17, pp. 220-228, Asia Pacific journal of clinical nutrition, McKinnon, Vic., C1

journal

Determination of trans fatty acid levels by FTIR in processed foods in Australia

J McCarthy, D Barr, A Sinclair

(2008), Vol. 17, pp. 391-396, Asia Pacific journal of clinical nutrition, McKinnon, Vic., C1

journal

Omega-3 polyunsaturated fatty acid supplementation reduces hypertension in TGR(mRen-2)27 rats

A Jayasooriya, D Begg, N Chen, M Mathai, A Sinclair, J Wilkinson-Berka, J Wark, H Weisinger, R Weisinger

(2008), Vol. 78, pp. 67-72, Prostaglandins, Leukotrienes and Essential Fatty Acids, London, Eng., C1-1

journal
2007

The extent and breadth of benefits from participating in chronic disease self-management courses: a national patient-reported outcomes survey

S Nolte, G Elsworth, A Sinclair, R Osborne

(2007), Vol. 65, pp. 351-360, Patient education counselling, Clare, Ireland, C1

journal

Plasma phospholipid and dietary fatty acids as predictors of type 2 diabetes: interpreting the role of linoleic acid 1-3

A Hodge, D English, K O'Dea, A Sinclair, M Makrides, R Gibson, G Giles

(2007), Vol. 86, pp. 189-197, American journal of clinical nutrition, Bethesda, Md., C1

journal

Failure of conjugated linoleic acid supplementation to enhance biosynthesis of docosahexaenoic acid from ?-linolenic acid in healthy human volunteers

N Attar-Bashi, R Weisinger, D Begg, A Sinclair, D Li

(2007), Vol. 76, pp. 121-130, Prostaglandins, leukotrienes and essential fatty acids, Edinburgh, Scotland, C1

journal

The problem of obesity : is there a role for antagonists of the renin-angiotensin system?

R Weisinger, D Begg, N Chen, M Jois, M Mathai, A Sinclair

(2007), Vol. 16, Asia Pacific journal of clinical nutrition, McKinnon, Vic., C1

journal

Dietary omega 3 fatty acids decrease intraocular pressure with age by increasing Aqueous outflow

C Nguyen, B Bui, A Sinclair, A Vingrys

(2007), Vol. 48, pp. 756-762, Investigative ophthalmology and visual science (IOVS), St. Louis, Mo., C1

journal

Plasma phospholipid fatty acid composition as a biomarker of habitual dietary fat intake in an ethnically diverse cohort

A Hodge, J Simpson, R Gibson, A Sinclair, M Makrides, K O'Dea, D English, G Giles

(2007), Vol. 17, pp. 415-426, Nutrition, metabolism & cardiovascular diseases, Napoli, Italy, C1

journal

Effects of gamma-tocopherol supplementation on thrombotic risk factors

I Singh, A Turner, A Sinclair, D Li, J Hawley

(2007), Vol. 16, pp. 422-428, Asia Pacific journal of clinical nutrition, McKinnon, Vic., C1

journal

Effect of dietary omega-3 fatty acid deficiency on heart rate variability in hooded rats

H Weisinger, N Salem Jr, K Makino, J Hibbeln, A Sinclair, R Weisinger, P DePetrillo

(2007), Vol. 3, pp. 208-214, Archives of medical science, Pozna?n, Poland, C1

journal

Omega 3 fatty acids and the brain : review of studies in depression

A Sinclair, D Begg, M Mathai, R Weisinger

(2007), Vol. 16, Asia Pacific journal of clinical nutrition, McKinnon, Vic., C1

journal

Seasonal variations of lipid content and composition in perna viridis

D Li, Y Zhang, A Sinclair

(2007), Vol. 42, pp. 1-9, Lipids, Berlin , Germany, C1-1

journal
2006

Low dose supplementation with two different marine oils does not reduce pro-inflammatory eicosanoids and cytokines in vivo

K Murphy, K Galvin, M Kiely, P Morrissey, N Mann, A Sinclair

(2006), Vol. 15, pp. 418-424, Asia Pacific journal of clinical nutrition, McKinnon, Vic., C1

journal

What is all the fuss about trans fatty acids?

A Sinclair, T Crowe, D Cameron-Smith

(2006), Vol. 73, pp. 13-15, Chemistry in Australia, Melbourne, Vic., C1

journal

Omega 6 to omega 3 fatty acid imbalance early in life leads to persistant reductions in DHA levels in glycerophospholipids in rat hypothalamus even after long-term omega 3 fatty acid repletion

D Li, H Weisinger, R Weisinger, M Mathai, J Armitage, A Vingrys, A Sinclair

(2006), Vol. 74, pp. 391-399, Prostaglandins, leukotrienes and essential fatty acids, Edinburgh, Scotland, C1

journal

Facts on fats

E Chong, A Sinclair, R Guymer

(2006), Vol. 34, pp. 464-471, Clinical and experimental ophthalmology, Carlton, Vic., C1

journal

The effect of exercise and training status on platelet activation: do cocoa polyphenols play a role?

I Singh, H Quinn, M Mok, R Southgate, A Turner, D Li, A Sinclair, J Hawley

(2006), Vol. 17, pp. 361-367, Platelets, Edinburgh, Scotland, C1-1

journal

A significant inverse relationship between concentrations of plasma hoocysteine and phospholipid docosahexaenoic acid in healthy male subjects

D Li, N Mann, A Sinclair

(2006), Vol. 41, pp. 85-89, Lipids, Berlin, Germany, C1-1

journal

Effect of feeding systems on omega-3 fatty acids, conjugated linoleic acid and trans fatty acids in Australian beef cuts: potential impact on humnan health

E Ponnampalam, N Mann, A Sinclair

(2006), Vol. 15, pp. 21-29, Asia Pacific journal of clinical nutrition, McKinnon, Vic., C1-1

journal

Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites

J Lee, S Pinnamaneni, S Eo, I Cho, J Pyo, C Kim, A Sinclair, M Febbraio, M Watt

(2006), Vol. 100, pp. 1467-1474, Journal of applied physiology, Bethesda, Md., C1-1

journal

Fatty acid composition of habitual omnivore and vegetarian diets

N Mann, Y Pirotta, S Oconnell, D Li, A Sinclair

(2006), Vol. 41, pp. 637-646, Lipids, Champaign, Ill., C1-1

journal
2005

Nutritional aspects of single cell oils:uses and applications of Arachidonic Acid and Docosahexaenoic Acid oils

A Sinclair, N Attar-Bashi, A Jayasooriya, R Gibson, M Makrides

(2005), pp. 182-201, Single cell oils, Champaign, Ill., B1-1

chapter

Effects of eicosapentaenoic acid in various clinical conditions

A Sinclair, J Wallace, M Martin, N Attar-Bashi, R Weisinger, D Li

(2005), pp. 361-394, Healthful Lipids, Champaign, Ill., B1-1

chapter

Perinatal ?-3 polyunsaturated fatty acid supply modifies brain zinc homeostasis during adulthood

A Jayasooriya, L Ackland, M Mathai, A Sinclair, H Weisinger, R Weisinger, J Halver, K Kitajka, L Puskas

(2005), Vol. 102, pp. 7133-7138, Proceedings of the National Academy of Sciences, Washington, D.C., C1

journal

Feed intake, growth, plasma glucose and urea nitrogen concentration, and cacass traits of lambs fed isoenergetic amounts of canola meal, soybean meal, and fish meal with forage based diet.

E Ponnampalam, A Egan, A Sinclair, B Leury

(2005), Vol. 58, pp. 245-252, Small Ruminant Research, Amsterdam, Netherlands, C1-1

journal

Gas chromatography-chemical ionization-mass spectrometric fatty acid analysis of a commercial supercritical carbon dioxide lipid extract from New Zealand green-lipped mussel (Perna canaliculus)

C Wolyniak, J Brenna, K Murphy, A Sinclair

(2005), Vol. 40, pp. 355-360, Lipids, New York, N.Y., C1-1

journal

Plasma coagulation factor VII activity and its corrlates in healthy men

D Li, A Turner, A Sinclair

(2005), Vol. 59, pp. 1423-1428, European journal of clinical nutrition, London, England, C1-1

journal

Lean meat and heart health

D Li, S Siriamornpun, M Wahlqvist, N Mann, A Sinclair

(2005), Vol. 14, pp. 113-119, Asia Pacific journal of clinical nutrition, McKinnon, Vic., C1-1

journal
2004

Immune function and adjustment style: do they predict survival in breast cancer?

R Osborne, A Sali, N Aaronson, G Elsworth, B Mdzewski, A Sinclair

(2004), Vol. 13, pp. 199-210, Psycho-oncology: journal of the psychological, social behavioral dimensions of cancer, London, England, C1-1

journal

?-linolenic acid and the risk of prostate cancer. What is the evidence?

N Attar-Bashi, A Frauman, A Sinclair

(2004), Vol. 171, pp. 1402-1407, Journal of urology, Baltimore, Md., C1-1

journal

Diacylglycerols from butterfat: production by Glycerolysis and short-path diltillation and analysis of physical properties

T Yang, H Zhang, H Mu, A Sinclair, X Xu

(2004), Vol. 81, pp. 979-987, Journal of the American oil chemists' society, Champaign, Ill., C1-1

journal

Does perinatal ?-3 polyunsaturated fatty acid deficiency increase appetite signaling?

M Mathai, M Soueid, N Chen, A Jayasooriya, A Sinclair, M Wlodek, H Weisinger, R Weisinger

(2004), Vol. 12, pp. 1886-1894, Obesity, Silver Spring, Md., C1-1

journal

Effects of dietary omega-3 polyunsaturated fatty acids on brain gene expression

K Kitajka, A Sinclair, R Weisinger, H Weisinger, M Mathai, A Jayasooriya, J Halver, L Puskas

(2004), Vol. 101, pp. 10931-10936, Proceedings of the National Academy of Sciences of the United States of America, Washington D.C., C1-1

journal
2003

Dietary flavanols and procyanidin oligomers from cocoa (Theobroma cacao) inhibit platelet function

K Murphy, A Chronopoulos, I Singh, M Francis, H Moriarty, M Pike, A Turner, N Mann, A Sinclair

(2003), Vol. 77, pp. 1466-1473, American journal of clinical nutrition, Bethesda, Md., C1-1

journal

Alpha-linolenic acid and heart disease

D Li, N Attar-Bashi, A Sinclair

(2003), pp. 245-259, Flaxseed in Human Nutrition, Champaign, Ill., B1-1

chapter

Omega-3 (n-3) fatty acids

D Li, O Bode, H Drummond, A Sinclair

(2003), pp. 225-262, Lipids for Functional Foods and Nutraceuticals, Bridgwater, England, B1-1

chapter

Dietary intakes and food sources of Omega-6 and Omega-3 polyunsaturated fatty acids.

B Meyer, N Mann, J Lewis, G Milligan, A Sinclair, P Howe

(2003), Vol. 38, pp. 391-398, Lipids, Champaign, Ill., C1-1

journal

Lipids and FA analysis of canine prostate tissue

N Attar-Bashi, K Orzeszko, R Slocombe, A Sinclair

(2003), Vol. 38, pp. 665-668, Lipids, Berlin, Germany, C1-1

journal

Increased blood pressure later in life may be associated with perinatal n-3 fatty acid deficiency

J Armitage, A Pearce, A Sinclair, A Vingrys, R Weisinger, H Weisinger

(2003), Vol. 38, pp. 459-464, Lipids, Berlin, Germany, C1-1

journal

Fatty acid and sterol composition of frozen and freeze-dried New Zealand green lipped mussel (Perna canaliculus) from three sites in New Zealand

K Murphy, N Mann, A Sinclair

(2003), Vol. 12, pp. 50-60, Asia Pacific journal of clinical nutrition, McKinnon, Vic., C1-1

journal
2002

What is the role of a-linolenic acid for mammals?

A Sinclair, N Attar-Bashi, D Li

(2002), Vol. 37, pp. 1113-1123, Lipids, Berlin , Germany, C1-1

journal

Dietary manipulation of muscle long-chain omega-3 and omega-6 fatty acids and sensory properties of lamb meat

E Ponnampalam, A Sinclair, A Egan, G Ferrier, B Leury

(2002), Vol. 60, pp. 125-132, Meat science, Barking, England, C1-1

journal

Relationship between platelet phospholipid FA and mean platelet volume in healthy men

D Li, A Turner, A Sinclair

(2002), Vol. 37, pp. 901-906, Lipids, Berlin , Germany, C1-1

journal

Short-term diets enriched in stearic or palmitic acids do not alter plasma lipids, platelet aggregation or platelet activation status

F Kelly, A Sinclair, N Mann, A Turner, F Raffin, M Blandford, M Pike

(2002), Vol. 56, pp. 490-499, European journal of clinical nutrition, London, England, C1-1

journal

Bread enriched with microencapsulated tuna oil increases plasma docosahexaenoic acid and total omega-3 fatty acids in humans

Y Yep, D Li, N Mann, O Bode, A Sinclair

(2002), Vol. 11, pp. 285-291, Asia Pacific journal of clinical nutrition, McKinnon, Vic., C1-1

journal

Macronutrient innovations: the role of fats and sterols in human health

D Li, A Sinclair

(2002), Vol. 11, Asia Pacific journal of clinical nutrition, McKinnon, Vic., C1-1

journal

Retinal sensitivity loss in third generation N-3 pufa-deficient rats

Andrew Sinclair, Richard Weisinger, T Moriguchi, D Mitchell, James Armitage, Harrison Weisinger, N Salem Jr, B Jeffrey, others

(2002), C1-1

journal

Lipid, FA, and sterol composition of New Zealand green lipped mussel (Perna canaliculus) and Tasmanian blue mussel (Mytilus edulis)

K Murphy, B Mooney, N Mann, P Nichols, A Sinclair

(2002), Vol. 37, pp. 587-595, Lipids, Berlin, Germany, C1-1

journal

Omega-3 polyunsaturated fatty acid contents of canned meats avaialbe in Australia

D Li, M Mansor, S Zhuo, T Woon, A Sinclair

(2002), Vol. 54, pp. 311-315, Food Australia, North Sydney, N.S.W., C1-1

journal

Effect of dietary fatty acids on the intestinal permeability of marker drug compounds in excised rat jejunum

D Vine, S Charman, P Gibson, A Sinclair, C Porter

(2002), Vol. 54, pp. 809-819, Journal of pharmacy and pharmacology:an international journal of pharmaceutical science, London, England, C1-1

journal

Regulation of desaturase gene expression by dietary fatty acids: effects on liver, brain and kidney

J Bellenger, S Bellenger, J Skrzypski, A Sinclair, J Poisson, M Narce

(2002), pp. 261-266, Fifth International Congress on Essential Fatty Acids and Eicosanoids, Taiwan, E1-1

conference
2001

Effect of Alpha-Linolenic acid on retnal function in mammals

A Sinclair, L Abedin

(2001), pp. 79-90, Omega-3 Fatty Acids: Chemistry, Nutrition, and Health Effects, Washington, D.C., Wash., B1-1

chapter

A stearic acid-rich diet improves thrombogenic and atherogenic risk factor profiles in healthy males

F Kelly, A Sinclair, N Mann, A Turner, L Abedin, D Li

(2001), Vol. 55, pp. 88-96, European journal of clinical nutrition, Basingstoke, England, C1-1

journal

The role of omega-3 polyunsaturated fatty acids in body fluid and energy homeostasis

Richard Weisinger, James Armitage, Peta Burns, Andrew Sinclair, Algis Vingrys, Harrison Weisinger

(2001), pp. 377-401, Fatty Acids, B1-1

chapter

The role of omega-3 polyunsaturated fatty acids in retinal function

A Vingrys, J Armitage, H Weisinger, B Bui, A Sinclair, R Weisinger

(2001), pp. 193-217, Fatty acids: physiological and behavioral functions, Totowa, N.J., B1-1

chapter

Effect of dietary modificatio of muscle long-chainN-3 fatty acid on plasma insulin and lipid metabolite, carcass traits, and fat deposition in lambs

E Ponnampalam, A Sinclair, A Egan, J Blangero, D Li, B Leury

(2001), Vol. 79, pp. 895-903, Journal of animal science: leading source of new knowledge and perspectives in animal science, Champaign, Ill., C1-1

journal

Effect of diets containing n-3 fatty acids on muscle long-chain n-3 fatty acid content in lambs fed low- and medium-quality roughage diets

E Ponnampalam, A Sinclair, A Egan, S Blakeley, B Leury

(2001), Vol. 79, pp. 698-706, Journal of animal science: leading source of new knowledge and perspectives in animal science, Champaign, Ill., C1-1

journal

Comparison of the color stability and lipid oxidative stability of fresh vacuum packaged lamb muscle containing elevated omega-3 and omega-6 fatty acid levels from dietary manipulation

E Ponnampalam, G Trout, A Sinclair, A Egan, B Leury

(2001), Vol. 58, pp. 151-161, Meat science, Amsterdam, Netherlands, C1-1

journal

The occurrence of trans-18:1 isomers in plasma lipids classes in humans

M Mansour, D Li, A Sinclair

(2001), Vol. 55, pp. 59-64, European journal of clinical nutrition, London, England, C1-1

journal

The a-linolenic acid content of green vegetables commonly available in Australia

C Pereira, D Li, A Sinclair

(2001), Vol. 71, pp. 223-228, International journal for vitamin and nutrition research, Berne, Switzerland, C1-1

journal

1-14C-Linoleic Acid distrubution in various tissue lipids of guinea pigs following an oral dose

Z Fu, N Attar-Bashi, A Sinclair

(2001), Vol. 36, pp. 255-260, Lipids, Berlin, Germany, C1-1

journal

Comparison of the color stability and lipid oxidative stability of fresh and vacuum packaged lamb muscle containing elevated omega-3 and omega-6 fatty acid levels from dietary manipulation

E Ponnampalam, G Trout, A Sinclair, A Egan, B Leury

(2001), Vol. 58, pp. 151-161, Meat science, Amsterdam, Netherlands, C1-1

journal

The influence of fish, meat and polyunsaturated fat intakes on platelet phopholipid polyunsaturated fatty acid in male Melbourne Chinese and Caucasian

D Li, H Zhang, B Hsu-Hage, M Wahlqvist, A Sinclair

(2001), Vol. 55, pp. 1036-1042, European journal of clinical nutrition, London, England, C1-1

journal

Comparison of the color stability and lipid oxidative stability fo fresh and vacuum packaged lamb muscle containing elevated omega-3 and omega-6 fatty acid levels from dietary manipulation

E Ponnampalam, G Trout, A Sinclair, A Egan, B Leury

(2001), Vol. 58, pp. 151-161, Meat science, Barking, England, C1-1

journal

Docosahexaeonoic acid and cerebral evolution

M Crawford, M Bloom, S Cunnane, H Holmsen, K Ghebremeskel, J Parkington, W Schmidt, A Sinclair, C Broadhurst

(2001), Vol. 88, pp. 6-17, World review of nutrition and dietetics, Basel, Switzerland, C1-1

journal

Funded Projects at Deakin

Australian Competitive Grants

To show Docosapentaenioc acid is a functional long-chain omega-3 fatty acid

Prof Andrew Sinclair, A/Prof David Cameron-Smith, A/Prof M Garg

MLA Grant - Research - Meat & Livestock Australia Limited

  • 2009: $43,000
  • 2008: $55,500
  • 2007: $60,000

Real Dairy Diets for Human Health

A/Prof David Cameron-Smith, Prof Andrew Sinclair

DIA Grant - Research - Dairy Innovation Australia Limited

  • 2010: $223,136
  • 2009: $396,764
  • 2008: $228,310

Triggering the dormant capacity of fish to make omega 3 fatty acids

Prof Giovanni Turchini, Prof Andrew Sinclair, Prof Leigh Ackland

ARC - Discovery Projects

  • 2014: $57,969
  • 2013: $56,269
  • 2012: $86,138
  • 2011: $82,946
  • 2010: $81,660

Trans fatty acids in Australian milk

Prof Andrew Sinclair

Dairy Australia Limited

  • 2009: $9,429
  • 2008: $20,629
  • 2007: $96,647
  • 2006: $58,936

Nanoliposomal delivery of DHA to neuronal cells

Prof Leigh Ackland, Prof Andrew Sinclair, A/Prof Cenk Suphioglu, Prof Harjinder Singh

ARC - Discovery Projects

  • 2014: $99,992
  • 2013: $97,059
  • 2012: $103,848

DPA (docosapentaenoic acid) Pilot study

Prof Andrew Sinclair, A/Prof Peter Meikle

MLA Grant - Research - Meat & Livestock Australia Limited

  • 2012: $14,003
  • 2011: $14,003

Industry and Other Funding

Analysis of omega 3 fatty acids in phospholipids from red blood cells

Prof Andrew Sinclair

  • 2009: $5,100

Analysis of fish oil vs krill oil bioavailability with HPLC-MS/MS methods

Prof Andrew Sinclair, Miss Samaneh Ghasemi Fard, Prof Giovanni Turchini

  • 2015: $13,120

Supervisions

Principal Supervisor
2014

Ashwantha Enjapoori

Thesis entitled: Monotreme Lactation: Characterisation of a novel protein, endocrine regulation andmiRNAs in milk

Doctor of Philosophy (Medicine), School of Medicine

2012

Manjula Nishanthi Kottahachchi Kankanamge

Thesis entitled: Characterization of postprandial phospholipid molecular species after dairy and soy breakfasts

Master of Science (Biology & Chemistry), BioDeakin

2011

Denovan Begg

Thesis entitled: Dietary Omega-3 Fatty Acids Modify Body Fluid and Cardiovascular Homeostasis

Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences

Gunveen Kaur

Thesis entitled: Docosapentaenoic Acid: Its Metabolism and Effect on Lipogenic Gene Expression

Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences

Associate Supervisor
2014

Vidhi Gaur

Thesis entitled: HDAC inhibition as a therapeutic potential to treat metabolic diseases

Doctor of Philosophy (Medicine), School of Medicine

2011

Petra Gran

Thesis entitled: Anabolic Signalling in Skeletal Muscle: Impact of Diet and Disease

Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences

2010

Sara Cicerale

Thesis entitled: Food as a Medicine: Healthful Oleocanthal in Australian Olive Oil (see comments15/6/10)

Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences

2008

Michelle Farnfield

Thesis entitled: Hypertrophic Signalling in Human Skeletal Muscle

Doctor of Philosophy (Nutrition & Exercise) (High Cost), School of Exercise and Nutrition Sciences