Dr Glenn Wadley

STAFF PROFILE

Position

Senior Lecturer

Faculty

Faculty of Health

Department

School of Exercise & Nut. Sci.

Campus

Melbourne Burwood Campus

Qualifications

Bachelor of Education, Deakin University, 1996
Bachelor of Applied Science (Human Movement), Deakin University, 1997
Master of Applied Science, Deakin University, 2000
Doctor of Philosophy, Deakin University, 2004
Graduate Certificate of Higher Education, Deakin University, 2012

Contact

glenn.wadley@deakin.edu.au
+61 3 924 46018

Research interests

Dr Wadleys research program has two major research streams centred on the impacts of physical activity and nutrition on adult health. The first stream examines the impacts of physical activity and the nutritional environments during early life on later adult health. The second research stream investigates exercise and antioxidant therapies for the treatment of type 2 diabetes and the regulation of mitochondrial biogenesis (synthesis) following exercise. Both of these topics have important implications for the treatment and prevention of type 2 diabetes and cardiovascular disease.

Affiliations

The Australian Physiological Society

Australian Diabetes Society

Australian Society for Medical Research

American Physiological Society
 

Teaching interests

School of Exercise and Nutrition Sciences, Honours Course Director

HSE303 Exercise Metabolism, Lecturer and Campus Chair (Burwood)

HSE201 Exercise Physiology, Lecturer

HBS400 Research Methods, Lecturer and Unit Chair

HSE401 Developing Research Skills, Lecturer and Unit Chair

HSE402/ HSN414 Honours Research Project, Lecturer and Unit Chair

Primary supervisor of Honours students, two PhD students and Co-supervisor of two PhD students
 

Conferences

International (* presenting author) *Strobel NA, Peake JM, Matsumoto A, Marsh SA, Coombes JS, Wadley GD. 2008. ACSM: Integrative Physiology of Exercise, East Carolina. *Wadley GD and McConell GK. 2008. Experimental Biology. San Diego. *Laker RC, Siebel AL, Wadley GD, McConell GK and Wlodek ME. 2007. 5th International Congress on Developmental Origins of Health & Disease. Perth. Ross RM, Wadley GD, Clark MG, Rattigan S and McConell GK*. 2007. American Diabetes Association, 67th Scientific Meeting, Chicago. *Wadley G. and McConell GK. 2006. American College of Sports Medicine: Integrative Physiology of Exercise. Indianapolis. *Siebel AL, Wadley GD, Leone F, Cooney G, McConell GK, Owens JA and Wlodek ME. 2006. 10th International Conference on Obesity. Sydney. *Owens JA, Leone F, Siebel AL, Wadley GD, McConell GK, Cooney G and Wlodek ME. 2006. Society for Gynecologic Investigation, Toronto. National Invited presentations Wadley GD. 2010. Do antioxidant vitamin supplements really prevent the beneficial increase in skeletal muscle mitochondrial biogenesis following exercise training? AussieMit 2010; The Garvan Institute of Medical Research, Sydney. Wadley GD. 2009. Reactive oxygen species: friends or foes? Exercise, Muscle and Metabolism Conference, Melbourne. Wadley GD. 2008. Regulation of mitochondrial biogenesis in skeletal muscle during exercise by reactive oxygen species. AussieMit Workshop New Developments in Mitochondrial Research, LaTrobe University, Melbourne.

Awards

2015: Vice Chancellor's Award for Teaching Excellence, Deakin University

2014: Award for Innovation in Teaching. Faculty of Health, Deakin University.

2004: National Heart Foundation of Australia Travel Grant

2000: National Heart Foundation of Australia Travel Grant

1999: Deakin University Postgraduate Research Scholarship

Publications

Filter by

2016

Ascorbic acid supplementation improves skeletal muscle oxidative stress and insulin sensitivity in people with type 2 diabetes: findings of a randomized controlled study

Mr Shaun Mason, Dr Paul Della Gatta, Prof Rod Snow, Prof Aaron Russell, Dr Glenn Wadley

(2016), Vol. 93, pp. 227-238, Free radical biology and medicine, Amsterdam, The Netherlands, C1

journal

Endurance training in early life results in long-term programming of heart mass in rats

Dr Glenn Wadley, Rhianna C. Laker, Dr Glenn McConell, Mary e. Wlodek

(2016), Vol. 4, pp. 1-14, Physiological reports, London, Eng., C1

journal

Maternal obesity in females born small: pregnancy complications and offspring disease risk

Dayana Mahizir, Jessica Briffa, Deanne Hryciw, Dr Glenn Wadley, Karen M Moritz, Mary e. Wlodek

(2016), Vol. 60, pp. 8-17, Molecular nutrition & food research, London, Eng., C1

journal
2015

Modulating exercise-induced hormesis: does less equal more?

Dr Jonathan Peake, James Markworth, Kazunori Nosaka, Truls Raastad, Dr Glenn Wadley, Vernon G. Coffey

(2015), Vol. 119, pp. 172-189, Journal of applied physiology, Bethesda, Md., C1

journal

Vitamin C and E supplementation prevents some of the cellular adaptations to endurance-training in humans

Mr Dale Morrison, Mr Jed Hughes, Dr Paul Della Gatta, Mr Shaun Mason, Dr Severine Lamon, Prof Aaron Russell, Dr Glenn Wadley

(2015), Vol. 89, pp. 852-862, Free radical biology and medicine, Amsterdam, The Netherlands, C1

journal

Uteroplacental insufficiency leads to hypertension, but not glucose intolerance or impaired skeletal muscle mitochondrial biogenesis, in 12-month-old rats

Melanie Tran, Margaret Young, Andrew J Jefferies, Deanne Hryciw, Michelle Ward, Prof Erica Fletcher, Mary e. Wlodek, Dr Glenn Wadley

(2015), Vol. 3, pp. 1-9, Physiological reports, London, Eng., C1

journal
2014

Altering the redox state of skeletal muscle by glutathione depletion increases the exercise-activation of PGC-1α

Natalie A. Strobel, Aya Matsumoto, Dr Jonathan Peake, Susan A. Marsh, Tina-Tinkara Peternelj, David Briskey, Robert Fassett, Jeff S Coombes, Dr Glenn Wadley

(2014), Vol. 2, pp. 1-10, Physiological reports, Malden, MA, C1

journal

Skeletal muscle reactive oxygen species: a target of good cop/bad cop for exercise and disease

Mr Shaun Mason, Dr Glenn Wadley

(2014), Vol. 19, pp. 97-106, Redox report, Leeds, England, C1

journal

Exercise as an intervention to improve metabolic outcomes after intrauterine growth restriction

Kathryn Gatford, Dr Gunveen Kaur, Filippe Falcao-Tebas, Dr Glenn Wadley, Mary e. Wlodek, Rhianna C. Laker, Peter Ebeling, Dr Glenn McConell

(2014), Vol. 306, pp. E999-E1012, American journal of physiology - endocrinology and metabolism, Bethesda, MD, C1

journal

Skeletal muscle mitochondria : a major player in exercise, health and disease.

Prof Aaron Russell, Dr Torie Foletta, Prof Rod Snow, Dr Glenn Wadley

(2014), Vol. 1840, pp. 1276-1284, Biochimica et Biophysica Acta - General Subjects, Amsterdam , Netherlands, C1

journal

Growth restriction in the rat alters expression of cardiac JAK/STAT genes in a sex-specific manner.

Samantha Van Der Linde, Tania Romano, Dr Glenn Wadley, A J Jeffries, Mary e. Wlodek, D H Hryciw

(2014), Vol. 5, pp. 314-321, Journal of developmental origins of health and disease, England, London, C1

journal

Growing healthy muscles to optimise metabolic health into adult life

Dr Stephanie Bayol, Dr Clinton Bruce, Dr Glenn Wadley

(2014), Vol. 5, pp. 420-434, Journal of developmental origins of health and disease, Cambridge, United Kingdom, C1

journal

High dose vitamin C supplementation increases skeletal muscle vitamin C concentration and SVCT2 transporter expression but does not alter redox status in healthy males

Mr Shaun Mason, Miss Raquel Baptista, Dr Paul Della Gatta, Dr Adel Yousif, Prof Aaron Russell, Dr Glenn Wadley

(2014), Vol. 77, pp. 130-138, Free Radical Biology and Medicine, Amsterdam, Neverlands, C1

journal
2013

Disruption of skeletal muscle mitochondrial network genes and miRNAs in amyotrophic lateral sclerosis

Prof Aaron Russell, Shogo Wada, Lodovica Vergani, M. Benjamin Hock, Dr Severine Lamon, Dr Bertrand Leger, Takashi Ushida, Romain Cartoni, Dr Glenn Wadley, Peter Hespel, Anastasia Kralli, Gianni Soraru, Corrado Angelini, Takayuki Akimoto

(2013), Vol. 49, pp. 107-117, Neurobiology of disease, Maryland Heights, Mo., C1

journal

Growth restriction in the rat alters expression of metabolic genes during postnatal cardiac development in a sex specific manner

Dr Glenn Wadley, G McConell, Craig Goodman, Andrew L. Siebel, Kerryn T Westcott, Mary e. Wlodek

(2013), Vol. 45, pp. 99-105, Physiological genomics, Bethesda, Md., C1

journal

Xanthine oxidase inhibition attenuates skeletal muscle signaling following acute exercise but does not impair mitochondrial adaptations to endurance training.

Dr Glenn Wadley, Marc Nicholas, Miss DANIELLE SARAH HIAM, G McConell

(2013), Vol. 304, pp. E853-E862, American journal of physiology - endocrinology and metabolism, Bethesda, Maryland, C1

journal
2012

Stage of perinatal development regulates skeletal muscle mitochondrial biogenesis and myogenic regulatory factor genes with little impact of growth restriction or cross-fostering

Rhianna C. Laker, Dr Glenn Wadley, G McConell, Mary e. Wlodek

(2012), Vol. 3, pp. 39-51, Journal of development origins of health and disease, Cambridge, England, C1

journal

Exercise early in life in rats born small does not normalize reductions in skeletal muscle PGC-1α in adulthood

Rhianna C. Laker, Mary e. Wlodek, Dr Glenn Wadley, Linda A. Gallo, A/Prof Peter Meikle, G McConell

(2012), Vol. 302, pp. E1221-E1230, AJP: Endocrinology and Metabolism, Bethesda, Md., C1

journal

Effect of pregnancy for females born small on later life metabolic disease risk

Melanie Tran, Linda A. Gallo, Dr Glenn Wadley, Andrew J Jefferies, Karen M Moritz, Mary e. Wlodek

(2012), Vol. 7, pp. 1-8, PLOS ONE, San Francisco, California, C1-1

journal

Skeletal muscle nitric oxide signalling and exercise: a focus on glucose metabolism

G McConell, Stephen Rattigan, R. S. Lee-Young, Dr Glenn Wadley, Troy L. Merry

(2012), Vol. 303, pp. E301-E307, American journal of physiology, endocrinology and metabolism, Bethesda, Maryland, C1-1

journal

Short-term intensified cycle training alters acute and chronic responses of PGC1α and cytochrome C oxidase IV to exercise in human skeletal muscle

Nigel K Stepto, Benziane Boubacar, Dr Glenn Wadley, Alexander V Chibalin, Benedict J. Canny, Nir Eynon, G McConell

(2012), Vol. 7, pp. 1-11, PLOS ONE, San Francisco, California, C1-1

journal
2011

Short-term exercise training early in life restores deficits in pancreatic B-cell mass associated with growth restriction in adult male rats

Rhianna C. Laker, Linda A. Gallo, Mary e. Wlodek, Andrew L. Siebel, Dr Glenn Wadley, G McConell

(2011), Vol. 301, pp. 931-940, AJP : endocrinology and metabolism, Bethesda, Md., C1

journal

Effect of L-arginine infusion on glucose disposal during exercise in humans

K. C. Linden, Dr Glenn Wadley, Dr Andrew Garnham, G McConell

(2011), Vol. 43, pp. 1626-1634, Medicine and science in sports and exercise, Philadelphia, Pa., C1

journal

Central infusion of leptin does not increase AMPK signaling in skeletal muscle of sheep

Rhianna C. Laker, Belinda A. Henry, Dr Glenn Wadley, Iain Clarke, Benedict J. Canny, G McConell

(2011), Vol. 300, pp. 511-518, American journal of physiology : regulatory, integrative and comparative physiology, Bethesda, Md., C1

journal

Antioxidant supplementation reduces skeletal muscle mitochondrial biogenesis

Natalie A. Strobel, Jonathon Peake, Aya Matsumoto, Susan A. Marsh, Jeff S Coombes, Dr Glenn Wadley

(2011), Vol. 43, pp. 1017-1024, Medicine and science in sports and exercise, Philadelphia, P. A., C1

journal
2010

Central role of nitric oxide synthase in AICAR and caffeine-induced mitochondrial biogenesis in L6 myocytes

G McConell, Gwyneth P. Y. Ng, Mr Matthew Phillips, Zhen Ruan, Lance Macaulay, Dr Glenn Wadley

(2010), Vol. 108, pp. 589-595, Journal of applied physiology, Bethesda, Md., C1-1

journal

High-dose antioxidant vitamin C supplementation does not prevent acute exercise-induced increases in markers of skeletal muscle mitochondrial biogenesis in rats

Dr Glenn Wadley, G McConell

(2010), Vol. 108, pp. 1719-1726, Journal of applied physiology, Bethesda, Md., C1

journal

N-Acetylcysteine infusion does not affect glucose disposal during prolonged moderate-intensity exercise in humans

Troy L. Merry, Dr Glenn Wadley, Chris Stathis, Dr Andrew Garnham, Stephen Rattigan, Prof Mark Hargreaves, G McConell

(2010), Vol. 588, pp. 1623-1634, The Journal of Physiology, Oxford, England, C1

journal

Growth restriction before and after birth increases kinase signaling pathways in the adult rat heart

Dr Glenn Wadley, Mary e. Wlodek, Gwyneth P. Y. Ng, Craig Goodman, Chris Stathis, G McConell

(2010), Vol. 1, pp. 376-385, Journal of developmental origins of health and disease, Cambridge, England, C1

journal
2008

Potential role of nitric oxide in contraction-stimulated glucose uptake and mitochondrial biogenesis in skeletal muscle

G McConell, Dr Glenn Wadley

(2008), Vol. 35, pp. 1488-1492, Clinical and experimental pharmacology and physiology, Oxford, England, C1-1

journal

Uteroplacental insufficiency and reducing litter size alters skeletal muscle mitochondrial biogenesis in a sex-specific manner in the adult rat

Dr Glenn Wadley, Andrew L. Siebel, Gregory Cooney, G McConell, Mary e. Wlodek, Julie A. Owens

(2008), Vol. 294, pp. 861-869, American journal of physiology : endocrinology and metabolism, Bethesda, Md., C1-1

journal

Differential attenuation of AMPK activation during acute exercise following exercise training or AICAR treatment

G McConell, A. Manimmanakorn, R. S. Lee-Young, Bruce E. Kemp, K. C. Linden, Dr Glenn Wadley

(2008), Vol. 105, pp. 1422-1427, Journal of applied physiology, Bethesda, Md., C1-1

journal
2007

Increased insulin-stimulated Akt pSer473 and cytosolic SHP2 protein abundance in human skeletal muscle following acute exercise and short-term training.

Dr Glenn Wadley, Dr Nicky Konstantopoulos, Lance Macaulay, Dr Kirsten Howlett, Dr Andrew Garnham, Prof Mark Hargreaves, A/Prof David Cameron-Smith

(2007), Vol. 102, pp. 1624-1631, Journal of applied physiology, Washington, D.C., C1-1

journal

NOS isoform-specific regulation of basal but not exercise-induced mitochondrial biogenesis in mouse skeletal muscle

Dr Glenn Wadley, J Choate, G McConell

(2007), Vol. 585, pp. 253-262, Journal of physiology, London, England, C1-1

journal

Local nitric oxide synthase inhibition reduces skeletal muscle glucose uptake but not capillary blood flow during in situ muscle contraction in rats

Renee M. Ross, Dr Glenn Wadley, Michael G. Clark, Stephen Rattigan, G McConell

(2007), Vol. 56, pp. 2885-2892, Diabetes, New York, N. Y., C1-1

journal

Effect of nitric oxide synthase inhibition on mitochondrial biogenesis in rat skeletal muscle

Dr Glenn Wadley, G McConell

(2007), Vol. 102, pp. 314-320, Journal of applied physiology, Bethesda, Md., C1-1

journal
2006

Effect of exercise intensity and hypoxia on skeletal muscle AMPK signaling and substrate metabolism in humans

Dr Glenn Wadley, R. S. Lee-Young, Benedict J. Canny, C Wasuntarawat, Zhi-Ping Chen, Prof Mark Hargreaves, Bruce E. Kemp, G McConell

(2006), Vol. 290, pp. E694-E702, American journal of physiology : endocrinology and metabolism, Bethesda, Md., C1-1

journal

L-Arginine infusion increases glucose clearance during prolonged exercise in humans

G McConell, N. N. Huynh, R. S. Lee-Young, Benedict J. Canny, Dr Glenn Wadley

(2006), Vol. 290, pp. E60-E66, American journal of physiology : endocrinology and metabolism, Bethesda, Md., C1-1

journal

Carbohydrate ingestion does not alter skeletal muscle AMPK signaling during exercise in humans

R. S. Lee-Young, Matthew J Palmer, K. C. Linden, Kieran LePlastrier, Benedict J. Canny, Prof Mark Hargreaves, Dr Glenn Wadley, Bruce E. Kemp, G McConell

(2006), Vol. 291, pp. E566-E573, American journal of physiology : endocrinology and metabolism, Bethesda, Md., C1-1

journal
2004

The effect of insulin and exercise on c-Cbl protein abundance and phosphorylation in insulin-resistant skeletal muscle in lean and obese Zucker rats.

Dr Glenn Wadley, Dr Clinton Bruce, Dr Nicky Konstantopoulos, J.S.L. Macauley, Dr Kirsten Howlett, John A. Hawley, A/Prof David Cameron-Smith

(2004), Vol. 47, pp. 412-419, Diabetologia, Berlin, Germany, C1

journal
2003

UCP3 protein expression is lower in type I, IIa and IIx muscle fiber types of endurance-trained compared to untrained subjects

Prof Aaron Russell, Dr Glenn Wadley, Matthijs K. C. Hesselink, Gert Schaart, Prof Sing Lo, Dr Bertrand Leger, Dr Andrew Garnham, Esther Kornips, A/Prof David Cameron-Smith, Jean-Paul Giacobino, Patrick Muzzin, Prof Rod Snow, Patrick Schrauwen

(2003), Vol. 445, pp. 563-569, Pfluegers Archiv : European journal of physiology, Berlin, Germany, C1

journal
2002

Slow component of VO2 kinetics: the effect of training status, fibre type, UCP3 mRNA and citrate synthase activity

Prof Aaron Russell, Dr Glenn Wadley, Prof Rod Snow, Jean-Paul Giacobino, Patrick Muzzin, Dr Andrew Garnham, A/Prof David Cameron-Smith

(2002), Vol. 26, pp. 157-164, International journal of obesity: and related metabolic disorders, Hampshire, England, C1

journal
1998

The relationship between repeated sprint ability and the aerobic and anaerobic energy systems

Dr Glenn Wadley, Dr Peter Le Rossignol

(1998), Vol. 1, pp. 100-110, Journal of science and medicine in sport, Amsterdam, The Netherlands, C1-1

journal