Dr Kirsten Howlett

STAFF PROFILE

Position

Senior Lecturer In Exercise Physiology

Faculty

Faculty of Health

Department

School of Exercise & Nut. Sci.

Campus

Geelong Waurn Ponds Campus

Qualifications

Bachelor of Science, University of Melbourne, 1994
Doctor of Philosophy, University of Melbourne, 1998
Graduate Certificate of Higher Education, Deakin University, 2013

Contact

Research interests

Dr Howletts research program is focused on understanding the physiological, cellular and molecular responses to exercise. In particular, her research examines the underlying mechanisms which mediate the beneficial effects of exercise on skeletal muscle insulin action, and the translation of this for the treatment and prevention of insulin resistance and associated disorders.

Affiliations

Australian Physiological Society

Teaching interests

HSE201: Exercise Physiology
Supervisors and co-supervisors honours and PhD students
 

Awards

Fulbright Post-doctoral Award
The Queens Trust Award for Young Australians
 

Publications

Filter by

2015

Metabolic remodelling in obesity and type 2 diabetes: pathological or protective mechanisms in response to nutrient excess?

Timothy Conner, Miss Sheree Martin, Dr Kirsten Howlett, A/Prof Sean Mcgee

(2015), Vol. 42, pp. 109-115, Clinical and Experimental Pharmacology and Physiology, England, London, C1

journal
2013

Exercise-induced muscle glucose uptake in mice with graded, muscle-specific GLUT-4 deletion

Dr Kirsten Howlett, S Andrikopoulos, Joe Proietto, Prof Mark Hargreaves

(2013), Vol. 1, pp. 1-7, Physiological reports, Chichester, England, C1

journal
2010

Akt, AS160, metabolic risk factors and aerobic fitness in middle-aged women

Dr Itamar Levinger, Dr Kirsten Howlett, Jonathon Peake, Dr Andrew Garnham, Prof David L Hare, G. Jerums, Prof Steve Selig, Craig Goodman

(2010), Vol. 16, pp. 98-104, Exercise immunology review, Champaign, Ill., C1-1

journal
2009

Brief intense interval exercise activates AMPK and p38 MAPK signaling and increases the expression of PGC-1α in human skeletal muscle

Martin J. Gibala, A/Prof Sean Mcgee, Dr Andrew Garnham, Dr Kirsten Howlett, Prof Rod Snow, Prof Mark Hargreaves

(2009), Vol. 106, pp. 929-934, Journal of applied physiology, Bethesda, Md., C1

journal
2008

The effect of exercise and insulin on AS160 phosphorylation and 14-3-3 binding capacity in human skeletal muscle

Dr Kirsten Howlett, Alicia Matthews, Dr Andrew Garnham, Kei Sakamoto

(2008), Vol. 294, pp. 401-407, American journal of physiology: endocrinology and metabolism, Bethesda, Md., C1

journal

Effect of high-intensity intermittent swimming on post-exercise insulin sensitivity in rat epitrochlearis muscle

Keiichi Koshinaka, Akiko Sano, Dr Kirsten Howlett, Takako Yamazaki, Maiko Sasaki, Kei Sakamoto, Kentaro Kawanaka

(2008), Vol. 57, pp. 749-756, Metabolism, Maryland Heights, Mo., C1-1

journal

AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5

A/Prof Sean Mcgee, Bryce J.W van Denderen, Dr Kirsten Howlett, Janelle Mollica, Jonathan D. Schertzer, Bruce E. Kemp, Prof Mark Hargreaves

(2008), Vol. 57, pp. 860-867, Diabetes, Alexandria, Va., C1-1

journal
2007

Increased insulin-stimulated Akt pSer473 and cytosolic SHP2 protein abundance in human skeletal muscle following acute exercise and short-term training.

Dr Glenn Wadley, Dr Nicky Konstantopoulos, Lance Macaulay, Dr Kirsten Howlett, Dr Andrew Garnham, Prof Mark Hargreaves, A/Prof David Cameron-Smith

(2007), Vol. 102, pp. 1624-1631, Journal of applied physiology, Washington, D.C., C1-1

journal

Resistance exercise and insulin regulate AS160 and interaction with 14-3-3 in human skeletal muscle

Dr Kirsten Howlett, Kei Sakamoto, Dr Andrew Garnham, A/Prof David Cameron-Smith, Prof Mark Hargreaves

(2007), Vol. 56, pp. 1608-1614, Diabetes, New York, N.Y., C1

journal
2006

Insulin-stimulated insulin recetor substrate-2-associated phosphatidylinositol 3-kinase activity is enhanced in human skeletal muscle after exercise.

Dr Kirsten Howlett, Kei Sakamoto, Haiyan Yu, Laurie J. Goodyear, Prof Mark Hargreaves

(2006), Vol. 55, pp. 1046-1052, Metabolism, Amsterdam, The Netherlands, C1

journal

Exercise does not alter subcellular localization, but increases phosphorylation of insulin-signaling proteins in human skeletal muscle

Chris Wilson, Prof Mark Hargreaves, Dr Kirsten Howlett

(2006), Vol. 290, pp. 341-346, American journal of physiology: endocrinology and metabolism, Bethesda, Md., C1

journal
2004

The effect of insulin and exercise on c-Cbl protein abundance and phosphorylation in insulin-resistant skeletal muscle in lean and obese Zucker rats.

Dr Glenn Wadley, Dr Clinton Bruce, Dr Nicky Konstantopoulos, J.S.L. Macauley, Dr Kirsten Howlett, John A. Hawley, A/Prof David Cameron-Smith

(2004), Vol. 47, pp. 412-419, Diabetologia, Berlin, Germany, C1

journal
2003

Regulation of glucose kinetics during intense exercise in humans: effects of α- and β-adrenergic blockade

Dr Kirsten Howlett, Mr Matthew Watt, Prof Mark Hargreaves, Prof Mark Febbraio

(2003), Vol. 52, pp. 1615-1620, Metabolism, clinical and experimental, Philadelphia, Pa., C1

journal

Peripheral insulin resistance develops in transgenic rats overexpressing phosphoenolpyruvate carboxykinase in the kidney

B J Lamont, S Andrikopoulos, A Funkat, J Favaloro, J M Ye, E W Kraegen, Dr Kirsten Howlett, J D Zajac, Joe Proietto

(2003), Vol. 46, pp. 1338-1347, Diabetologia, New York, N.Y., C1

journal
2002

Insulin signaling after exercise in insulin receptor substrate-2-deficient mice

Dr Kirsten Howlett, Kei Sakamoto, Michael Hirschman, William Aschenbach, Matthew Dow, Morris F. White, Laurie J. Goodyear

(2002), Vol. 51, pp. 479-483, Diabetes, New York, N.Y., C1-1

journal

Effect of AICAR treatment on gycogen metabolism in skeletal muscle

William Aschenbach, Michael Hirschman, Nobuharu Fujii, Kei Sakamoto, Dr Kirsten Howlett, Laurie J. Goodyear

(2002), Vol. 51, pp. 567-573, Diabetes, New York, N.Y., C1-1

journal
2001

Splanchnic blood flow and hepatic glucose production in exercising humans : role of renin-angiotensin system

Raynald Bergeron, M Kjaer, Lene Simonsen, J Bulow, Dorthe Skovgaard, Dr Kirsten Howlett, Henrik Galbo

(2001), Vol. 281, pp. 1854-1861, American journal of physiology. Regulatory, integrative, and comparative physiology, Bethesda, Md., C1-1

journal

Effect of prior exercise on glucose metabolism in trained men.

Mr Adam Rose, Dr Kirsten Howlett, Douglas S. King, Prof Mark Hargreaves

(2001), Vol. 281, pp. E766-E771, American journal of physiology : endocrinology and metabolism, Bethesada, Md., C1

journal

Carbohydrate metabolism during exercise in females : effect of reduced fat availability

Dr Kirsten Howlett, Prof Lawrence Spriet, Prof Mark Hargreaves

(2001), Vol. 50, pp. 481-487, Metabolism, clinical and experimental, Duluth, Minn., C1

journal

Adrenaline increases skeletal muscle glycogenolysis, pyruvate dehydrogenase activation and carbohydrate oxidation during moderate exercise in humans

Mr Matthew Watt, Dr Kirsten Howlett, Prof Mark Febbraio, Prof Lawrence Spriet, Prof Mark Hargreaves

(2001), Vol. 534, pp. 269-278, Journal of physiology, Cambrigde, England, C1

journal
2000

Adrenaline and glycogenolysis in skeletal muscle during exercise : a study in adrenalectomised humans

M Kjaer, Dr Kirsten Howlett, J. Langfort, T Zimmerman-Belsing, J Lorentsen, J Bulow, J. Ihlemann, U Feldt-Rasmussen, H Galbo

(2000), Vol. 528, pp. 371-378, Journal of physiology, Oxford, England, C1-1

journal
1999

Glucose production during strenuous exercise in humans : role of epinephrine

Dr Kirsten Howlett, Prof Mark Febbraio, Prof Mark Hargreaves

(1999), Vol. 276, pp. E1130-E1135, American journal of physiology, Bethesda, Md., C1-1

journal

Effect of adrenaline on glucose kinetics during exercise in adrenalectomised humans

Dr Kirsten Howlett, H Galbo, J Lorentsen, R Bergeron, T Zimmerman-Belsing, J Bulow, U Feldt-Rasmussen, M Kjaer

(1999), Vol. 519, pp. 911-921, Journal of physiology, Oxford, England, C1-1

journal
1998

Effect of increased blood glucose availability on glucose kinetics during exercise

Dr Kirsten Howlett, Damien Angus, Joe Proietto, Prof Mark Hargreaves

(1998), Vol. 84, pp. 1413-1417, Journal of applied physiology, Bethesda, Md., C1-1

journal
1996

Effect of heat stress on glucose kinetics during exercise

Prof Mark Hargreaves, Damien Angus, Dr Kirsten Howlett, Nelly Marmy Conus, Prof Mark Febbraio

(1996), Vol. 81, pp. 1594-1597, Journal of applied physiology, Bethesda, Md., C1-1

journal