Prof Wei Duan

STAFF PROFILE

Position

Professor

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Contact

wei.duan@deakin.edu.au
+61 3 522 71149

Research interests

Professor Duan's research focuses on developing nucleic acid aptamer technology platforms for cancer biotechnology, focusing on cancer stem cell-targeted drug, siRNA and miRNA delivery using nanoparticles as well as aptamer-based molecular imaging for early detection of cancer and accurate staging. He heads a cross-disciplinary and translational research team consisting of cancer biologists, oncologists, molecular and cell biologists, material scientists, organic chemists, drug developers, pharmaceutical scientists and mechanical and electronic engineers across several faculties, research centres and teaching hospitals in Deakin. He is also involved in developing novel aptamer-based and microfluidic lab-on-a-chip devices for the application in biodefense, forensic medicine and rapid diagnostics at the point of care. He has published over 160 peer-reviewed original research papers and review articles in international refereed journals, with an h-index of 30 (average citation per article of 25).  Professor Duan has filed 5 international patents on cancer stem related aptamers.  He serves as the Editor-in-Chief for the journal “Drug Design, Development and Therapy” (https://www.dovepress.com/drug-design-development-and-therapy-journal).


Professors Duan has been frequently invited to address international conferences on biomedical research, drug development and molecular medicine.

6. Wei Duan, “Aptamer therapeutics: the 21st century’s magic bullet of nanomedicine”, Second International Conference on Drug Discovery and Therapy'. Feb 1-4, 2010. Dubai, United Arab Emirates.

8. Wei Duan,  RNA Aptamer: The Next Generation of Cancer Stem Cell-targeted Molecular Imaging,  BIT’s 9th Annual Congress of International Drug Discovery Science and Technology, Nov 3-6, 2011, Shenzhen, China;

10. Wei Duan, RNA aptamer-guided nanodrug delivery for the 21st century cancer medicine, 6th Annual Meeting of the Australian chapter of the Controlled Release Society, Melbourne, Nov 26-27, 2012.

11. Wei Duan, “Aptamer-guided nano drug delivery systems for cancer therapy”, Nano- and Microparticle-based drug and vaccine delivery, The 6th Joint Australia-New Zealand chapters of the Controlled Release Society, Brisbane, July 4-5, 2013.

12. W. Duan, “The use of RNA aptamers for diagnosis: detecting low levels of EpCAM in paraffin embedded tissues“, Aptamer in Medicine and Perspectives, Oct 4-5, 2013, Naples, Italy.

13. D.Xiang. S. Shigdar, W. Duan, “Targeting cancer stem cells in vivo using RNA aptamers“, 16th International Symposium on Molecular Medicine/The 18th World Congress on Advances in Oncology, 10-12, October, 2013, Hotel Creta Maris Resort, Greece.

15. T Wang, S Shigdar, Wei Duan, “An aptamer-based siRNA in vivo delivery system targeting cancer stem cells, 5th FIP Pharmaceutical Sciences World Congress, Melbourne, Australia, April 13-16, 2014.

16. Shigdar S, Xiang D, Duan W. Aptamers as effective cancer stem cell targeting modalities. Aptamers- 2014, 24-25th March 2014, Oxford, UK. Aug 25-27, 2015.

17. Wei Duan, “Cancer stem cells targeted delivery of siRNA in vivo: translating Nobel Prize-winning technology to clinic”, 8th Dubai International Conference for Medical Sciences, Ded15-17, 2014, Dubai, United Arab Emirates. 

18. Wei Duan, “Cancer stem cell targeted delivery of siRNA to overcome induced chemoresistance”, European Pharma Congress, Aug 25-27, 2015, Valencia, Spain.

19. Wei Duan, “RNA aptamer-guided in vivo RNAi to overcome chemoresistance”, Health forum of the Silk Road-Int Summit Forum of Research and Development on Traditional Chinese Medicine and Ethnic Medicine, Oct 17-18, 2015, Kunlun Hotel, Urumuqi, Xingjiang, P.R. China.

Knowledge areas

aptamer, chemical antibody, molecular cell bioogy, cancer stem cell, targeted drug delivery, nanomedicine, nanotechnology, novel cancer treatment and diagnostics

Conferences

Invited addresses: 1. Wei Duan, A Novel Paradigm in Mammalian Cell Signaling, Signal TransductionTargets for effective therapeutics, Cambridge Healthtech Institute, Seaport Hotel, Boston, MA, USA, November 8-9, 2004. [My talk was reviewed in Rounding up the usual suspects: protein kinases as the therapeutic targets, S.B. Shears, Drug Discovery Today.10(4):240-242, 2005.] 2. Wei Duan, Signaling via a novel integral plasma membrane pool of protein kinase C, The Hunter Meeting of Cell Biology, Sydney, Australia, 6-8 April, 2005. 3. Wei Duan, Herbal Medicine In AustraliaTransforming Ancient Remedy With Nanotechnology, 59th Indian Pharmaceutical Congress, Varanasi-221 005, Uttar Pradesh, India, 20-23 December, 2007. 4. Wei Duan, Development of Molecular Medicine that Specifically Targets Protein Kinase C in Heart Failure, 10th South China International Congress of Cardiology, Dongfang Hotel, Guangzhou, China, 10-13, April, 2008. 5. Wei Duan, Targeted drug delivery using RNA aptamer and nanoparticlesthe miracle of nanomedicine for the 21st century. VII Thailand Research Fund (TRF) Annual Congress. October 16-18, 2008, Holiday Inn Resort Regent Beach, Cha-Am, Thailand. 6. Wei Duan, Aptamer therapeutics: the 21st centurys magic bullet of nanomedicine, Second International Conference on Drug Discovery and Therapy'. February 1-4, 2010. Dubai, United Arab Emirates. 7. Wei Duan, Nucleic acid aptamer: the pearl in the crown of nanomedicine for molecular imaging of cancer, The 4th International Symposium on Bioanalysis, Biomedical Engineering and Nanotechnology (ISBBN 2010), Hunan University in Changsha, Hunan, China (June 3-6, 2010). 8. Wei Duan, RNA Aptamer: The Next Generation of Cancer Stem Cell-targeted Molecular Imaging, BITs 9th Annual Congress of International Drug Discovery Science and Technology --- Re-think Drug Innovations in Green-Eco Era (Session 7-1-2: Nucleic Acid Therapeutics), November 3-6, 2011, Shenzhen, China.

Media appearances

Being an Australian leader in developing aptamers against cancer stem cells,  Professor Duan is well recognised for his innovative and translational medical research.  For example, his work of developing RNA aptamer for cancer diagnosis and treatment was cited by Senator Kim Carr (Minister for Innovation), in his press release on 7 January 2011 as a fine example of the world-class research carried out by Australian leading researchers funded by the Department of Innovation, Industry, Science and Research, Australian Government.
(http://www.industry.gov.au/science/internationalcollaboration/Documents/Cancer_Diagnostics_Case_Study.pdf)

In addition, Professor Duan’s work has enjoined wide coverage by both domestic and international media (for a TV interview: http://www.youtube.com/watch?feature=player_embedded&v=cn_up61UnQY#at=244).

Newspaper coverage of Professor Duan's research:
1) The Australian newspaper, March 19, 2011, Article by Reporter Alexander Gambotto-Burke.
2) The Age newspaper, Melbourne: July 5, 2010,  Article by Reporter Danny Rose. 

3) Australian Broadcast Corporation, National Australia Radio, March 11, 2011, Interview with Desley Blanch.
4)  Australian Broadcast Corporation, Melbourne Radio, February 17 (17:35), Prime time Interview with Lindy Burns.
5)  Victoria TV Channel 31: Special features at 18:30, 9 March 2011, Length: 7 min 42 sec.
6)  Geelong Advertiser: July 6, 2010, Article by Reporter Joel Cresswell.
7)  Geelong Independent: February 25, 2011, Article by Erin Pearson.

Publications

Filter by

2016

Application of Aptamers in Histopathology.

Dr Sarah Shigdar, Li Lv, Lifen Wang, Prof Wei Duan

(2016), pp. 191-196, Nucleic acid aptamers : selection, characterization and application, New York, N.Y., B1

chapter

Development of a sustained release solid dispersion using swellable polymer by melting method

Tuong Ngoc-Gia Nguyen, Dr Phuong Tran, Toi Van Vo, Prof Wei Duan, Dr Truong Dinh Thao Tran

(2016), Vol. 33, pp. 102-109, Pharmaceutical research, Berlin, Germany, C1

journal

An investigation of effects of modification processes on physical properties and mechanism of drug release for sustaining drug release from modified rice

Vuong Duy Ngo, Thinh Duc Luu, Toi Van Vo, Van-Thanh Tran, Prof Wei Duan, Dr Phuong Tran, Thao T-D Tran

(2016), Vol. 67, pp. 1-7, Materials science and engineering C, Amsterdam, The Netherlands, C1

journal

ANXA2 enhances the progression of hepatocellular carcinoma via remodeling the cell motility associated structures

Hongyan Shi, Li Xiao, Prof Wei Duan, Huimin He, Lele Ma, Miaomiao Da, Yan Duan, Qian Wang, Huayi Wu, Xigui Song, Yingchun Hou

(2016), Vol. 85, pp. 26-33, Micron, Amsterdam, The Netherlands, C1

journal

Tailored mesoporous silica nanoparticles for controlled drug delivery: platform fabrication, targeted delivery, and computational design and analysis

Ms Xiaodong She, Mr Lijue Chen, Mr Zhifeng Yi, Mr Chengpeng Li, Canzhong He, Miss Chunfang Feng, Mr Tao Wang, Dr Sarah Shigdar, Prof Wei Duan, Prof Lingxue Kong

(2016), Vol. 16, pp. 1-40, Mini-reviews in medicinal chemistry, Beijing, China, C1

journal

Aptamers: a promising chemical antibody for cancer therapy

Gang Zhou, George S Wilson, Lionel Hebbard, Prof Wei Duan, Christopher Liddle, Jacob George, Liang Qiao

(2016), Vol. 7, pp. 13446-13463, Oncotarget, Albany, N.Y., C1

journal

Investigation of Fucoidan–oleic acid conjugate for delivery of Curcumin and Paclitaxel

Uyen Thao Phan, Khanh Tu Nguyen, Toi Van Vo, Prof Wei Duan, Dr Phuong Tran, Thao T-D Tran

(2016), Vol. 16, pp. 1281-1287, Anti-cancer agents in medicinal chemistry, Beijing, China, C1

journal

Perspectives of engineered marine derived polymers for biomedical nanoparticles

Khanh Thi My Tran, Toi Van Vo, Prof Wei Duan, Dr Phuong Tran, Thao T-D Tran

(2016), Vol. 22, pp. 2844-2856, Current pharmaceutical design, Beijing, China, C1

journal
2015

Aptamer-mediated cancer gene therapy

Mr Dongxi Xiang, Dr Sarah Shigdar, Greg G. Qiao, Shu-Feng Zhou, Dr Yong Li, Ming Q. Wei, Liang Qiao, Hadi Shamaileh, Yimin Zhu, Conglong Zheng, Prof Wei Duan

(2015), Vol. 15, pp. 109-119, Current Gene Therapy, Bussum, Netherlands, C1

journal

Graphene quantum dots induce apoptosis, autophagy, and inflammatory response via p38 mitogen-activated protein kinase and nuclear factor-κB mediated signaling pathways in activated THP-1 macrophages.

Yiru Qin, Zhi-Wei Zhou, Shu-Ting Pan, Zhi-Xu He, Xueji Zhang, Jia-Xuan Qiu, Prof Wei Duan, Tianxin Yang, Shu-Feng Zhou

(2015), Vol. 327, pp. 62-76, Toxicology, Ireland, C1

journal

Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells.

Yong-Hui Ding, Zhi-Wei Zhou, Chun-Fang Ha, Xue-Yu Zhang, Shu-Ting Pan, Zhi-Xu He, Jeffrey Edelman, Ms Mei Wang, Yin-Xue Yang, Prof Wei Duan, Tianxin Yang, Jia-Xuan Qiu, Shu-Feng Zhou

(2015), Vol. 9, pp. 425-464, Drug Design, Development and Therapy, New Zealand, C1

journal

Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells

Yan-Yang Wang, Yin-Xue Yang, Ren Zhao, Shu-Ting Pan, Hong Zhe, Zhi-Xu He, Prof Wei Duan, Xueji Zhang, Tianxin Yang, Jia-Xuan Qiu, Shu-Feng Zhou

(2015), Vol. 9, pp. 993-1026, Drug design, development and therapy, Auckland, New Zealand, C1

journal

Clinical association between pharmacogenomics and adverse drug reactions

Zhi-Wei Zhou, Xiao-Wu Chen, Kevin B Sneed, Yin-Xue Yang, Xueji Zhang, Zhi-Xu He, Kevin Chow, Tianxin Yang, Prof Wei Duan, Shu-Feng Zhou

(2015), Vol. 75, pp. 589-631, Drugs, Basel, Switzerland, C1

journal

The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells

Jin-Ping Li, Yin-Xue Yang, Qi-Lun Liu, Zhi-Wei Zhou, Shu-Ting Pan, Zhi-Xu He, Xueji Zhang, Tianxin Yang, Si-Yuan Pan, Prof Wei Duan, Shu-Ming He, Xiao-Wu Chen, Jia-Xuan Qiu, Shu-Feng Zhou

(2015), Vol. 9, pp. 1027-1062, Drug design, development and therapy, Macclesfield, Eng., C1

journal

Cisplatin-induced formation of biocompatible and biodegradable polypeptide-based vesicles for targeted anticancer drug delivery

Steven Shirbin, Katharina Ladewig, Qiang Fu, Molly Klimak, Xiaqing Zhang, Prof Wei Duan, Greg G. Qiao

(2015), Vol. 16, pp. 2463-2474, Biomacromolecules, Washington, D.C., C1

journal

Chansu inhibits the expression of cortactin in colon cancer cell lines in vitro and in vivo

Chun Li, Saeed M. Hashimi, Siyu Cao, Ji Qi, David A. Good, Prof Wei Duan, Ming Q. Wei

(2015), Vol. 15, pp. 1-8, BMC complementary and alternative medicine, London, Eng., C1

journal

Clinical pharmacology of dipeptidyl peptidase 4 inhibitors indicated for the treatment of type 2 diabetes mellitus

Xiao-Wu Chen, Zhi-Xu He, Zhi-Wei Zhou, Tianxin Yang, Xueji Zhang, Yin-Xue Yang, Prof Wei Duan, Shu-Feng Zhou

(2015), Vol. 42, pp. 999-1024, Clinical and experimental pharmacology and physiology, London, Eng., C1

journal

Novel targeting of PEGylated liposomes for codelivery of TGF-β1 siRNA and four antitubercular drugs to human macrophages for the treatment of mycobacterial infection: a quantitative proteomic study

Ning-Kui Niu, Juan-Juan Yin, Yin-Xue Yang, Zi-Li Wang, Zhi-Wei Zhou, Zhi-Xu He, Xiao-Wu Chen, Xueji Zhang, Prof Wei Duan, Tianxin Yang, Shu-Feng Zhou

(2015), Vol. 9, pp. 4441-4470, Drug design, development and therapy, Macclesfield, Eng., C1

journal

Cytokine networks and cancer stem cells

Mr Clifford Liongue, Prof Alister Ward, Prof Wei Duan, Dr Sarah Shigdar

(2015), pp. 67-87, Cancer stem cells : emerging concepts and future perspectives in translational oncology, Berlin, Germany, B1

chapter

EpCAM aptamer-mediated survivin silencing sensitized cancer stem cells to doxorubicin in a breast cancer model

Mr Tao Wang, Michael P. Gantier, Mr Dongxi Xiang, Andrew G.D Bean, Matthew P Bruce, Shu-Feng Zhou, Dr Mustafa Khasraw, Prof Alister Ward, Li Wang, ming wei, Mr Hadi Al Shamaileh, Mr Lijue Chen, Ms Xiaodong She, Ms Jia Lin, Prof Lingxue Kong, Dr Sarah Shigdar, Prof Wei Duan

(2015), Vol. 5, pp. 1456-1472, Theranostics, Wyoming, N.S.W., C1

journal

Cancer stem cell targeted therapy: progress amid controversies

Mr Tao Wang, Dr Sarah Shigdar, Michael P. Gantier, Yingchun Hou, Li Wang, Dr Yong Li, Mr Hadi Al Shamaileh, Wang Yin, Shu-Feng Zhou, Xinhan Zhao, Prof Wei Duan

(2015), Vol. 6, pp. 44191-44206, Oncotarget, Orchard Park, N.Y., C1

journal

An update on the clinical pharmacology of the dipeptidyl peptidase 4 inhibitor alogliptin used for the treatment of type 2 diabetes mellitus.

Xiao-Wu Chen, Zhi-Xu He, Zhi-Wei Zhou, Tianxin Yang, Xueji Zhang, Yin-Xue Yang, Prof Wei Duan, Shu-Feng Zhou

(2015), Vol. 42, pp. 1225-1238, Clinical and experimental pharmacology and physiology, London, Eng., C1

journal

Sch9 regulates intracellular protein ubiquitination by controlling stress responses

Beibei Qie, Zhou Lyu, Lei Lyu, Jun Liu, Xuejie Gao, Yanyan Liu, Prof Wei Duan, Nianhui Zhang, Linfang Du, Ke Liu

(2015), Vol. 5, pp. 290-300, Redox biology, Amsterdam, The Netherlands, C1

journal

Controllable drug uptake and nongenomic response through estrogen-anchored cyclodextrin drug complex

Juan-Juan Yin, Stepan P Shumyak, Christopher Burgess, Zhi-Wei Zhou, Zhi-Xu He, Xue-Ji Zhang, Shu-Ting Pan, Tian-Xin Yang, Prof Wei Duan, Jia-Xuan Qiu, Shu-Feng Zhou

(2015), Vol. 10, pp. 4717-4730, International Journal of Nanomedicine, Auckland, N. Z., C1

journal

Overcoming acquired drug resistance in colorectal cancer cells by targeted delivery of 5-FU with EGF grafted hollow mesoporous silica nanoparticles

Mr Lijue Chen, Ms Xiaodong She, Mr Tao Wang, Dr Li He, Dr Sarah Shigdar, Prof Wei Duan, Prof Lingxue Kong

(2015), Vol. 7, pp. 14080-14092, Nanoscale, Cambridge, Eng., C1

journal

The control of epidermal growth factor grafted on mesoporous silica nanoparticles for targeted delivery

Ms Xiaodong She, Mr Lijue Chen, Dr Leonora Velleman, Mr Chengpeng Li, Canzhong He, John Denman, Mr Tao Wang, Dr Sarah Shigdar, Prof Wei Duan, Prof Lingxue Kong

(2015), Vol. 3, pp. 6094-6104, Journal of materials chemistry B, Cambridge, Eng., C1

journal

Nucleic acid aptamer-guided cancer therapeutics and diagnostics: the next generation of cancer medicine

Mr Dongxi Xiang, Dr Sarah Shigdar, Greg G. Qiao, Mr Tao Wang, Prof Abbas Kouzani, Shu-Feng Zhou, Prof Lingxue Kong, Dr Yong Li, Chunwen Pu, Prof Wei Duan

(2015), Vol. 5, pp. 23-42, Theranostics, Wyoming, N.S.W., C1

journal
2014

A surface-stress-based microcantilever aptasensor

Dr Yang Lim, Prof Abbas Kouzani, Prof Wei Duan, Dr Jane Dai, A/Prof Akif Kaynak, Douglas Mair

(2014), Vol. 8, pp. 15-24, IEEE transactions on biomedical circuits and systems, Piscataway, NJ, C1

journal

Improved efficacy and reduced toxicity of doxorubicin encapsulated in sulfatide-containing nanoliposome in a glioma model

Ms Jia Lin, Dr Sarah Shigdar, Ding Zhi Fang, Dognxi Xiang, Ming Qian Wei, A/Prof Andrew Danks, Prof Lingxue Kong, Lianghong Li, Liang Qiao, Prof Wei Duan

(2014), Vol. 9, pp. 1-13, Plos One, San Francisco, CA, C1

journal

Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K/Akt/mTOR pathway in human non-small cell lung cancer cells.

Yan-Cong Li, Shu-Ming He, Zhi-Xu He, Minghua Li, Yingxue Yang, Jian-Xin Pang, Xueji Zhang, Kevin Chow, Qingyu Zhou, Prof Wei Duan, Zhi-Wei Zhou, Tianxin Yang, Gui-Hua Huang, Aibing Liu, Jia-Xuan Qiu, A/Prof Jun-Ping Liu, Shu-Feng Zhou

(2014), Vol. 344, pp. 239-259, Cancer Letters, Shannon, County Clare, Ireland, C1

journal

Synergistic effects of IAP inhibitor LCL161 and paclitaxel on hepatocellular carcinoma cells

Aiping Tian, George S Wilson, Stefanus Lie, Guang Wu, Zenan Hu, Lionel Hebbard, Prof Wei Duan, Jacob George, Liang Qiao

(2014), Vol. 351, pp. 232-241, Cancer Letters, Shannon, County Clare, Ireland, C1

journal

Prediction of the likelihood of drug interactions with kinase inhibitors based on in vitro and computational studies

Zhi-Xin Wang, Jiazi Sun, Caitlin E Howell, Qing-Yu Zhou, Zhi-Xu He, Tianxin Yang, Helen Chew, Prof Wei Duan, Zhi-Wei Zhou, Prof Jagat Kanwar, Shu-Feng Zhou

(2014), Vol. 28, pp. 551-582, Fundamental & Clinical Pharmacology, Abingdon, England, C1

journal

CD44 variant 6 is associated with prostate cancer metastasis and chemo-/radioresistance.

Jie Ni, Paul J. Cozzi, Jingli Hao, Julia Beretov, Lei Chang, Prof Wei Duan, Dr Sarah Shigdar, Warick Delprado, Peter H. Graham, Joseph Bucci, John Kearsley, Dr Yong Li

(2014), Vol. 74, pp. 602-617, Prostate, Hoboken, NJ, C1

journal

Design and evaluation of a microcantilever aptasensor

Yang Choon Lim, Prof Abbas Kouzani, Prof Wei Duan, Dr Jane Dai, A/Prof Akif Kaynak, Douglas Mair

(2014), pp. 221-224, IEEE 2014 : Circuits and Systems Circuits and Systems (ISCAS) Proceedings of the 2014 IEEE International Symposium, Piscataway, N.J., E1

conference

Cancer stem cells in prostate cancer chemoresistance

Jie Ni, Paul J. Cozzi, Jingli Hao, Prof Wei Duan, Peter H. Graham, John Kearsley, Dr Yong Li

(2014), Vol. 14, pp. 225-240, Current cancer drug targets, Bussum, Netherlands, C1

journal

Smoothened activates breast cancer stem-like cell and promotes tumorigenesis and metastasis of breast cancer

Lixia Wang, Prof Wei Duan, Le Kang, Jun Mao, Xiaotang Yu, Shujun Fan, Lianhong Li, Yajun Tao

(2014), Vol. 68, pp. 1099-1104, Biomedicine & pharmacotherapy, Amsterdam, The Netherlands, C1

journal

Epigallocatechin-3-gallate induces the apoptosis of hepatocellular carcinoma LM6 cells but not non-cancerous liver cells

Yunjuan Zhang, Prof Wei Duan, Lawrence Owusu, Dachang Wu, Yi Xin

(2014), Vol. 35, pp. 117-124, International Journal of Molecular Medicine, Athens, Greece, C1

journal

Cancer stem cells: a contentious hypothesis now moving forward

Michael O Connor, Mr Dongxi Xiang, Dr Sarah Shigdar, Ms Joanna Macdonald, Dr Yong Li, Mr Tao Wang, Chunwen Pu, Zhidong Wang, Liang Qiao, Prof Wei Duan

(2014), Vol. 344, pp. 180-187, Cancer letters, Shannon, Ireland, C1

journal

Fabrication of high specificity hollow mesoporous silica nanoparticles assisted by Eudragit for targeted drug delivery.

Ms Xiaodong She, Mr Lijue Chen, Dr Leonora Velleman, Mr Chengpeng Li, Dr Haijin Zhu, Canzhong He, Mr Tao Wang, Dr Sarah Shigdar, Prof Wei Duan, Prof Lingxue Kong

(2014), Vol. 445, pp. 151-160, Journal of Colloid and Interface Science, United States, C1

journal
2013

Localized surface plasmon resonance: nano-sinusoid arrays

Mr Daryoush Mortazavi, Prof Abbas Kouzani, L. Matekovits, Prof Wei Duan

(2013), Vol. 27, pp. 638-648, Journal of electromagnetic waves and applications, London, Eng., C1

journal

Cloning of the crustacean hyperglycemic hormone and evidence for molt-inhibiting hormone within the central nervous system of the blue crab Portunus pelagicus

Mr Michael James Stewart, Praphaporn Stewart, Morakot Sroyraya, Nantawan Soonklang, Scott Cummins, A/Prof Peter Hanna, Prof Wei Duan, Prof Prasert Sobhon

(2013), Vol. 164, pp. 276-290, Comparative biochemistry and physiology. Part A : molecular & integrative physiology, New York, N.Y., C1

journal

Epithelial cell adhesion molecule (EpCAM) is associated with prostate cancer metastasis and chemo/radioresistance via the PI3K/Akt/mTOR signaling pathway

Jie Ni, Paul J. Cozzi, Jingli Hao, Julia Beretov, Lei Chang, Prof Wei Duan, Dr Sarah Shigdar, Warick Delprado, Peter H. Graham, Joseph Bucci, John Kearsley, Dr Yong Li

(2013), Vol. 45, pp. 2736-2748, International journal of biochemistry and cell biology, Amsterdam, The Netherlands, C1

journal

Peptide-fluorescent bacteria complex as luminescent reagents for cancer diagnosis

Bing Dong, Anxin Wang, Lihua Yuan, Lisha Chen, Kefeng Pu, Prof Wei Duan, Xiyun Yan, Yimin Zhu

(2013), Vol. 8, pp. -, PLOS One, San Francisco, California, C1

journal

Selection of DNA aptamers against epithelial cell adhesion molecule for cancer cell imaging and circulating tumor cell capture

Yanling Song, Zhi Zhu, Yuan An, Weiting Zhang, Huimin Zhang, Dr Dan Liu, Chundong Yu, Prof Wei Duan, Chaoyong J. Yang

(2013), Vol. 85, pp. 4141-4149, Analytical chemistry, Washington DC, C1

journal

Synthesis and biological evaluation of novel folic acid receptor-targeted, β-cyclodextrin-based drug complexes for cancer treatment

Juan-Juan Yin, Sonali Sharma, Stepan P Shumyak, Zhi-Xin Wang, Zhi-Wei Zhou, Yangde Zhang, Peixuan Guo, Chen-Zhong Li, Prof Jagat Kanwar, Tianxin Yang, Prof Shyam S. Mohapatra, Wanqing Liu, Prof Wei Duan, Jian-Cheng Wang, Qi Li, Xueji Zhang, Jun Tan, Lee Jia, Jun Liang, Ming Qian Wei, Xiaotian Li, Shu-Feng Zhou

(2013), Vol. 8, pp. 1-20, PLOS one, San Francisco, California, C1

journal

Tumoricidal effects of the JAK inhibitor Ruxolitinib (INC424) on hepatocellular carcinoma in vitro

George S Wilson, Aiping Tian, Lionel Hebbard, Prof Wei Duan, Jacob George, Xun Li, Liang Qiao

(2013), Vol. 341, pp. 224-230, Cancer letters, Amsterdam, The Netherlands, C1

journal

Anti-metastatic and differential effects on protein expression of epigallocatechin-3-gallate in HCCLM6 hepatocellular carcinoma cells

Yunjuan Zhang, Lawrence Owusu, Prof Wei Duan, Tao Jiang, Shizhu Zang, Ayaz Ahmed, Yi Xin

(2013), Vol. 32, pp. 959-964, International journal of molecular medicine, Athens, Greece, C1

journal

Efficacy of using cancer stem cell markers in isolating and characterizing liver cancer stem cells

George S Wilson, Zenan Hu, Prof Wei Duan, Aiping Tian, Xin M Wang, Duncan McLeod, Vincent Lam, Jacob George, Liang Qiao

(2013), Vol. 22, pp. 2655-2664, Stem Cells and Development, New Rochelle, NY, C1

journal

The mechanisms of Chansu in inducing efficient apoptosis in colon cancer cells

Chun Li, Saeed M. Hashimi, Siyu Cao, Dr Albert Mellick, Prof Wei Duan, David A. Good, Ming Qian Wei

(2013), Vol. 2013, pp. 1-11, Evidence-based complementary and alternative medicine, New York, N. Y., C1

journal

Role of surface charge and oxidative stress in cytotoxicity and genotoxicity of graphene oxide towards human lung fibroblast cells

Anxin Wang, Kefeng Pu, Bing Dong, Yang Liu, Liming Zhang, Zhijun Zhang, Prof Wei Duan, Yimin Zhu

(2013), Vol. 33, pp. 1156-1164, Journal of applied toxicology, Bognor Regis, England, C1-1

journal

Inflammation and cancer stem cells

Dr Sarah Shigdar, Dr Yong Li, Santuna Bhattacharya, Michael Liam O`Connor, Chunwen Pu, Ms Jia Lin, Mr Tao Wang, Mr Dongxi Xiang, Prof Lingxue Kong, Ming Qian Wei, Yimin Zhu, Prof Shufeng Zhou, Prof Wei Duan

(2013), Vol. 345, pp. 271-278, Cancer letters, Amsterdam, The Netherlands, C1

journal

Aptamers as theranostic agents: modifications, serum stability and functionalisation

Dr Sarah Shigdar, Ms Joanna Macdonald, Michael Liam O`Connor, Mr Tao Wang, Mr Dongxi Xiang, Hadi Al.Shamaileh, Liang Qiao, Ming Qian Wei, Shu-Feng Zhou, Yimin Zhu, Prof Lingxue Kong, Santanu Bhattacharya, ChunGuang Li, Prof Wei Duan

(2013), Vol. 13, pp. 13624-13637, Sensors, Basel, Switzerland, C1

journal
2012

Developing lspr design guidelines

Mr Daryoush Mortazavi, Prof Abbas Kouzani, A/Prof Akif Kaynak, Prof Wei Duan

(2012), Vol. 126, pp. 203-235, Progress in electromagnetics research, Cambridge, Mass., C1

journal

Clostridial spores for cancer therapy : targeting solid tumour microenvironment

Brittany Umer, David A. Good, Jozef Anne, Prof Wei Duan, Ming Qian Wei

(2012), Vol. 2012, pp. 1-8, Journal of toxicology, New York, N.Y., C1

journal

Role of multidrug resistance associated proteins in drug development

Shu-Feng Zhou, A/Prof Jun-Ping Liu, Ming Qian Wei, Prof Wei Duan

(2012), pp. 3-35, Multidrug resistance : a global concern, San Francisco, Calif., B1

chapter

Enhanced antitumor efficacy and reduced systemic toxicity of sulfatide containing nanoliposomal doxorubicin in a xenograft model of colorectal cancer

Ms Jia Lin, Yan Yu, Dr Sarah Shigdar, Ding Zhi Fang, Jun Rong Du, Ming Qian Wei, A/Prof Andrew Danks, Ke Liu, Prof Wei Duan

(2012), Vol. 7, pp. 1-10, Plos One, San Francisco, Calif., C1

journal

Role of the EpCAM (CD326) in prostate cancer metastasis and progression

Jie Ni, Paul J. Cozzi, Prof Wei Duan, Dr Sarah Shigdar, Peter H. Graham, Kearsley H. John, Dr Yong Li

(2012), Vol. 31, pp. 779-791, Cancer metastasis reviews, New York, N. Y., C1

journal

Apoptosis and microRNA aberrations in cancer

Chun Li, Saeed M. Hashimi, David A. Good, Siyu Cao, Prof Wei Duan, Dr Prue Plummer, Dr Albert Mellick, Ming Qian Wei

(2012), Vol. 39, pp. 739-746, Clinical and experimental pharmacology and physiology, Australia, C1

journal

Cancer stem cell targeting : the next generation of cancer therapy and molecular imaging

Dr Sarah Shigdar, Ms Jia Lin, Dr Yong Li, Chaoyong J. Yang, Ming Qian Wei, Yimin Zhu, Hui Liu, Prof Wei Duan

(2012), Vol. 3, pp. 227-244, Therapeutic delivery, London, England, C1

journal

Aptamers and nanomedicine

Dr Sarah Shigdar, Adam Smith, Prof Wei Duan

(2012), pp. 275-296, Nanotechnology in health care, Singapore, Singapore, B1-1

chapter
2011

Nano-plasmonic biosensors : a review

Mr Daryoush Mortazavi, Prof Abbas Kouzani, A/Prof Akif Kaynak, Prof Wei Duan

(2011), pp. 31-36, CME 2011 : Proceedings of the 2011 IEEE/ICME International Conference on Complex Medical Engineering, Harbin Heilongjiang, China, E1

conference

Effects of lipoprotein lipase gene variations, a high-carbohydrate low-fat diet, and gender on serum lipid profiles in healthy Chinese Han youth

Xin Huang, Ren Rong Gong, Ms Jia Lin, Ronghui Li, Li Ying Xiao, Prof Wei Duan, Ding Zhi Fang

(2011), Vol. 5, pp. 198-204, Bioscience trends, Tokyo, Japan, C1

journal

Associations of the SREBP-1c gene polymorphism with gender-specific changes in serum lipids induced by a high-carbohydrate diet in healthy Chinese youth

Zhen Zhang, Ren Rong Gong, Juan Du, Li Ying Xiao, Prof Wei Duan, Xue Dong Zhou, Ding Zhi Fang

(2011), Vol. 36, pp. 226-232, Applied physiology, nutrition and metabolism, Ottawa, Canada, C1

journal

Clinical applications of aptamers and nucleic acid therapeutics in haematological malignancies

Dr Sarah Shigdar, Prof Alister Ward, Abhijit De, Chaoyong J. Yang, Ming Qian Wei, Prof Wei Duan

(2011), Vol. 155, pp. 3-13, British journal of haematology, Oxford, U. K., C1

journal

Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study

Ya-He Liu, Sui-Lin Mo, Hui-Chang Bi, Bing-Fang Hu, Chun-Guang Li, Yi-Tao Wang, Ling Huang, Min Huang, Prof Wei Duan, A/Prof Jun-Ping Liu, Ming Qian Wei, Shu-Feng Zhou

(2011), Vol. 41, pp. 259-280, Xenobiotica, London, U. K., C1

journal

Elevated levels of triglyceride and triglyceride-rich lipoprotein triglyceride induced by a high-carbohydrate diet is associated with polymorphisms of AP0A5-1131T>C and AP0C3-482C> in chinese healthy young adults

Ms Jia Lin, Ding Zhi Fang, Juan Du, Dr Sarah Shigdar, Li Ying Xiao, Xue Dong Zhou, Prof Wei Duan

(2011), Vol. 58, pp. 150-157, Annals of nutrition and metabolism, Basel, Switzerland, C1

journal

Cancer gene therapy : developments and future perspectives

David A. Good, Prof Wei Duan, Jozef Anne, Ming Qian Wei

(2011), pp. 299-314, Gene therapy - Developments and Future Perspectives, Rijeka, Croatia, B1

chapter
2010

Aptasensors : a review

Dr Yang Lim, Prof Abbas Kouzani, Prof Wei Duan

(2010), Vol. 6, pp. 93-105, Journal of biomedical nanotechnology, Valencia, Calif., C1

journal

Effects of design parameters on sensitivity of microcantilever biosensors

Dr Yang Lim, Prof Abbas Kouzani, Prof Wei Duan, A/Prof Akif Kaynak

(2010), pp. 177-181, IEEE/ICME 2010 : Proceedings of the 2010 International Conference on Complex Medical Engineering, Gold Coast, Queensland, E1

conference

Disposition pathways and pharmacokinetics of herbal medicines in humans

Shu-Ming He, Chun-Guang Li, A/Prof Jun-Ping Liu, Eli Chan, Prof Wei Duan, Shu-Feng Zhou

(2010), Vol. 17, pp. 4072-4113, Current medicinal chemistry, Amsterdam, The Netherlands, C1

journal

Spermatogenesis in the blue swimming crab, Portunus pelagicus, and evidence for histones in mature sperm nuclei

Mr Michael James Stewart, Praphaporn Stewart, Nantawan Soonklang, V Linthong, A/Prof Peter Hanna, Prof Wei Duan, Prof Prasert Sobhon

(2010), Vol. 42, pp. 137-150, Tissue and cell, United Kingdom, C1

journal

Lab-on-a-chip : a component view

Dr Yang Lim, Prof Abbas Kouzani, Prof Wei Duan

(2010), Vol. 16, pp. 1995-2015, Microsystem technologies : sensors actuators systems integration, Heidelberg, Germany, C1

journal

Aptamer therapeutics: the 21st century's magic bullet of nanomedicine

Dr Sarah Shigdar, Jasmina Luczo, Ming Qian Wei, A/Prof Richard Bell, A/Prof Andrew Danks, Ke Liu, Prof Wei Duan

(2010), Vol. 1, pp. 118-124, Open conference proceedings journal, Bussum, The Netherlands, C1-1

journal
2009

Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6

Sui-Lin Mo, Ya-He Liu, Prof Wei Duan, Ming Qian Wei, Prof Jagat Kanwar, Shu-Feng Zhou

(2009), Vol. 10, pp. 730-753, Current drug metabolism, Hilversum, The Netherlands, C1

journal

Aptasensors design considerations

Dr Yang Lim, Prof Abbas Kouzani, Prof Wei Duan

(2009), pp. 118-127, Computational intelligence and intelligent systems, Berlin, Germany, B1

chapter

GSK3β modulates PACAP-induced neuritogenesis in PC12 cells by acting downstream of Rap1 in a caveolae-dependent manner

Weishi Zhang, Adam Smith, A/Prof Jun-Ping Liu, Dr Steve Cheung, Shu-Feng Zhou, Ke Liu, A/Prof Qiu Tian Li, Prof Wei Duan

(2009), Vol. 21, pp. 237-245, Cellular signalling, Amsterdam, The Netherlands, C1

journal

Insights into the Structure, Function, and Regulation of Human Cytochrome P450 1A2

Shu-Feng Zhou, Li-Ping Yang, Ming Qian Wei, Prof Wei Duan, Eli Chan

(2009), Vol. 10, pp. 713-729, Current drug metabolism, Bussum, Netherlands, C1-1

journal
2008

Protein kinase C isozymes as potential therapeutic targets in immune disorders

Matthew R Lee, Prof Wei Duan, Seng-Lai Tan

(2008), Vol. 12, pp. 535-552, Expert opinion on therapeutic targets, London, England, C1

journal

Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc

Dakang Xu, Julie Dwyer, Dr Li He, Prof Wei Duan, A/Prof Jun-Ping Liu

(2008), Vol. 283, pp. 23567-23580, Journal of biological chemistry, Bethesda, Md, C1

journal

Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development

Shu-Feng Zhou, Lin-Lin Wang, Yuan Ming Di, Charlie Xue, Prof Wei Duan, Chun-Guang Li, Dr Yong Li

(2008), Vol. 15, pp. 1981-2039, Current medicinal chemistry, Schiphol, Netherlands, C1

journal

Clincial pharmacogenetics and potential application in personalized medicine

Shu-Feng Zhou, Yuan Ming Di, Eli Chan, Yaomin Du, Vivian Deh-Wei Chow, Charlie Xue, Xinsheng Lai, Jian-Cheng Wang, Chun-Guang Li, Min Tian, Prof Wei Duan

(2008), Vol. 9, pp. 738-784, Current drug metabolism, Hilversum, Netherlands, C1

journal

The C-terminus of PRK2/PKNγ is required for optimal activation by RhoA in a GTP-dependent manner

Wee Guan Lim, Xiao Chen, A/Prof Jun-Ping Liu, Bee Jen Tan, Shu-Feng Zhou, Adam Smith, Mr Nathaniel WILSON GRIFFITH Lees, Liansheng Hou, Fukang Gu, Xi-Yong Yu, Yaomin Du, Derek Smith, Chandra Verma, Ke Liu, Prof Wei Duan

(2008), Vol. 479, pp. 170-178, Archives of biochemistry and biophysics, New York, N.Y., C1

journal
2007

Role of the ATP-binding cassette drug transporters in the intestinal absorption of tanshinone IIB, one of the major active diterpenoids from the root of Salvia miltiorrhiza

Xi-Yong Yu, Zhi-Wei Zhou, Shu Guang Lin, Xiao Chen, Xue-Qing Yu, Jun Liang, Prof Wei Duan, Jing Yuan Wen, Xiao-Tian Li, Shu-Feng Zhou

(2007), Vol. 37, pp. 375-415, Xenobiotica: the fate of foregn compounds in biological systems, Abingdon, England, C1

journal

Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimers disease, across the blood-brain

Xi-Yong Yu, Shu Guang Lin, Xiao Chen, Zhi-Wei Zhou, Jun Liang, Prof Wei Duan, Balram Chowbay, Jing Yuan Wen, Eli Chan, Jie Cao, Chun-Guang Li, Shu-Feng Zhou

(2007), Vol. 8, pp. 365-377, Current drug metabolism, Hilversum, Netherlands, C1

journal

Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: Application to cellular metabolism and accumulation studies

Ze-Ping Hu, Xiao-Xia Yang, Xiao Chen, Eli Chan, Prof Wei Duan, Shu-Feng Zhou

(2007), Vol. 850, pp. 575-580, Journal of chromatography. B, analytical technologies in the biomedical and life sciences, Amsterdam, Nertherlands, C1

journal

Tanshinone IIB, a primary active constituent from Salvia miltiorrhza, exhibits neuro-protective activity in experimentally stroked rats

Xi-Yong Yu, Shu Guang Lin, Zhi-Wei Zhou, Xiao Chen, Jun Liang, Prof Wei Duan, Xue-Qing Yu, Jing Yuan Wen, Balram Chowbay, Chun-Guang Li, Fwu-Shan Sheu, Eli Chan, Shu-Feng Zhou

(2007), Vol. 417, pp. 261-265, Neuroscience letters, Limerick, Ireland, C1

journal

Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge

Xi-Yong Yu, Shu Guang Lin, Zhi-Wei Zhou, Xiao Chen, Jun Liang, Pei Qing Liu, Prof Wei Duan, Balram Chowbay, Jing Yuan Wen, Shu-Feng Zhou

(2007), Vol. 8, pp. 1-16, Current drug metabolism, Hilversum, The Netherlands, C1

journal

Emerging host cell targets for hepatitis C therapy

Yupeng He, Prof Wei Duan, Seng-Lai Tan

(2007), Vol. 12, pp. 209-217, Drug discovery today, Barking, England, C1

journal

A mechanistic study on altered pharmacokinetics of irinotecan by St. Johns wort

Ze-Ping Hu, Xiao-Xia Yang, Xiao Chen, Eli Chan, Prof Wei Duan, Min Huang, Xue-Qing Yu, Jing Yuan Wen, Shu-Feng Zhou, Jie Cao

(2007), Vol. 8, pp. 157-171, Current drug metabolism, Hilversum, The Netherlands, C1

journal

Design of new oxazaphosphorine anticancer drugs

Jun Liang, Min Huang, Prof Wei Duan, Xue-Qing Yu, Shu-Feng Zhou

(2007), Vol. 13, pp. 963-978, Current pharmaceutical design, Hilversum, The Netherlands, C1

journal

Histological studies of the ovaries of two tropical portunid crabs, Portunus pelagicus (L.) and Scylla serrata (F.)

Mr Michael James Stewart, Nantawan Soonklang, Praphaporn Stewart, A/Prof Peter Hanna, Wanichanon Chaitip, Prof Andrew Parratt, Prof Wei Duan, Prof Prasert Sobhon

(2007), Vol. 50, pp. 85-97, Invertebrate reproduction and development, Rehovot, Israel, C1

journal

Sulfatide-tenascin interaction mediates binding to the extracellular matrix and endocytic uptake of liposomes in glioma cells

Ke Shao, Qingsong Hou, Mei Lin Go, Prof Wei Duan, Dr Steve Cheung, S Feng, Kim Ping Wong, A Yoram, Weishi Zhang, Zhili Huang, A/Prof Qiu Tian Li

(2007), Vol. 64, pp. 506-515, Cellular and molecular life sciences, Basel, Switzerland, C1

journal

Role of P-glycoprotein in limiting the brain penetration of glabridin, an active isoflavan from the root of Glycyrrhiza glabra.

Xi-Yong Yu, Zhi-Wei Zhou, Shu Guang Lin, Xiao Chen, Xue-Qing Yu, Jun Liang, Prof Wei Duan, Jing Yuan Wen, Xiao-Tian Li, Shu-Feng Zhou, Balram Chowbay, Eli Chan, Jie Cao, Chun-Guang Li, Charlie Xue

(2007), Vol. 24, pp. 1668-1690, Pharmaceutical research, Delft, The Netherlands, C1

journal

Pituitary adenylate cyclase-activating polypeptide induces translocation of its G-protein-coupled receptor into caveolin-enriched membrane microdomains, leading to enhanced cyclic AMP generation and neurite outgrowth in PC12 cells

Weishi Zhang, Prof Wei Duan, Dr Steve Cheung, Zhili Huang, Ke Shao, A/Prof Qiu Tian Li

(2007), Vol. 103, pp. 1157-1167, Journal of neurochemistry, Chichester, England, C1

journal
2006

The very C-terminus of protein kinase CĹ is critical for the full catalytic competence but its hydrophobic motif is dispensable for the interaction with 3-phosphoinositide-dependent kinase-1

Yimin Zhu, Derek Smith, Chandra Verma, Wee Guan Lim, Bee Jen Tan, Jeffrey S. Armstrong, Shu-Feng Zhou, Eli Chan, Seng-Lai Tan, Yi-Zhun Zhu, Dr Steve Cheung, Prof Wei Duan

(2006), Vol. 18, pp. 807-818, Cellular signalling, Amsterdam, Netherlands, C1-1

journal

Analysis of cardioprotective effects using purified Saliva miltiorrhiza extract on isolated rat hearts

Piek Ngoh Chang, Jian Chun Mao, Shan Hong Huang, Li Ning, Zhong Jung Wang Wang, Todd On, Prof Wei Duan, Yi-Zhun Zhu

(2006), Vol. 101, pp. 245-249, Journal of Pharmacological Sciences, Japan, C1-1

journal

Drug-herb interactions: eliminating toxicity with hard drug design.

Xiao-Xia Yang, Ze-Ping Hu, Prof Wei Duan, Yi-Zhun Zhu, Shu-Feng Zhou

(2006), Vol. 12, pp. 4649-4664, Current pharmaceutical design, Hilversum, The Netherlands, C1-1

journal

St. Johns wort attenuates irinotecan-induced diarhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosis

Ze-Ping Hu, Xiao-Xia Yang, Sui Yung Chan, An-Long Xu, Prof Wei Duan, Yi-Zhun Zhu, Fwu-Shan Sheu, Urs Alex Boelsterli, Eli Chan, Qiang Zhang, Jian-Cheng Wang, Pui Lai Rachel Ee, Hwee Ling Koh, Min Huang, Shu-Feng Zhou

(2006), Vol. 216, pp. 225-237, Toxicology and applied pharmacology, San Diego Calif., C1-1

journal

Intracellular drug delivery by sulfatide-mediated liposomes to gliomas

Ke Shao, Qingsong Hou, Prof Wei Duan, Mei Lin Go, Kim Ping Wong, A/Prof Qiu Tian Li

(2006), Vol. 115, pp. 150-157, Journal of controlled release, Amsterdam, The Netherlands, C1-1

journal

Pharmacokinetics of recombinant human endostatin in rats

Xiao-Xia Yang, Ze-Ping Hu, Eli Chan, Prof Wei Duan, Shu-Feng Zhou

(2006), Vol. 7, pp. 565-576, Current drug metabolism, Hilversum, The Netherlands, C1-1

journal

Early induction of chalpains in rotenone-mediated neuronal apoptosis

Minghui Jessica Chen, Ms Yann Yap, Meng Shyan Choy, Chor Hui Vivien Koh, Sze Jee Seet, Prof Wei Duan, Matthew Whiteman, Dr Steve Cheung

(2006), Vol. 397, pp. 69-73, Neuroscience letters, Limerick, Ireland, C1-1

journal

Monitoring of immune responses to a herbal immuno-modulator in patients with advanced colorectal cancer.

Xiao Chen, Ze-Ping Hu, Xiao-Xia Yang, Min Huang, Yihuai Gao, Wenbo Tang, Sui Yung Chan, Xihu Dai, Jinxian Ye, Paul Chi-Lui Ho, Prof Wei Duan, Hongyuan Yang, Yi-Zhun Zhu, Shu-Feng Zhou

(2006), Vol. 6, pp. 499-508, International immumopharmacology, Barking, England, C1-1

journal

Topotecan is a substrate for multidrug resistance associated protein 4

Quan Tian, Jing Zhang, Sui Yung Chan, Theresa May Chin Tan, Prof Wei Duan, Min Huang, Yi-Zhun Zhu, Eli Chan, Qiang Yu, Yu-Qiang Nie, Paul Chi-Lui Ho, Q Li, Ka-Yun Ng, Hongyuan Yang, Hong Wei, Jin-Song Bian, Shu-Feng Zhou

(2006), Vol. 7, pp. 105-118, Current drug metabolism, Hilversum, Netherlands, C1-1

journal

The very C-terminus of PRK1/PKN is essential for its activation by RhoA and downstream signaling

Wee Guan Lim, Bee Jen Tan, Yimin Zhu, Shu-Feng Zhou, Jeffrey S. Armstrong, A/Prof Qiu Tian Li, A/Prof Q Dong, Eli Chan, Derek Smith, Chandra Verma, Seng-Lai Tan, Prof Wei Duan

(2006), Vol. 18, pp. 1473-1481, Cellular signalling, Amsterdam, Netherlands, C1-1

journal

Nitric oxide protects against mitochondrial permeabilizastion induced by gluthathione depletion: role of S-nitrosylation?

Matthew Whiteman, Yee-Liu Chua, Dawei Zhang, Prof Wei Duan, Yih-Cherng Liou, Jeffrey S. Armstrong

(2006), Vol. 339, pp. 255-262, Biochemical and biophysical research comminications, San Diego Calif., C1-1

journal

A study of the effects of flux density and frequency on Pulsed electromagnetic field on Neurite outgrowth in PC12 cells.

Yang Zhang, Jun Ding, Prof Wei Duan

(2006), Vol. 32, pp. 1-9, Journal of biological physics: an intrnational journal for the formulation and application of physical and mathematical models in the biological sciences, Amsterdam, The Netherlands, C1-1

journal

Use of in vitro critical inhibitory concentration, a novel approach to predict in vivo synergistic bactericidal effect of combined amikacin and piperacillin against pseudomonas aeruginosa in a systemic rat infection model

Eli Chan, Shu-Feng Zhou, Srikumar Sahasranaman, Prof Wei Duan

(2006), Vol. 23, pp. 729-741, Pharmaceutical research, New York, N.Y., C1-1

journal

A comparison study of cerebral protection using Ginkgo biloba extract and Losartan on stroked rats

K.P. Loh, L.S. Low, W.H. Wong, Shu-Feng Zhou, Shan Hong Huang, R.De Silva, Prof Wei Duan, W.H. Chou, Yi-Zhun Zhu

(2006), Vol. 398, pp. 28-33, Neuroscienceletters, Limerick, Ireland, C1-1

journal

U18666A-mediated apoptosis in cultured murine cortical neurons : role of caspases, calpains and kinases

Chor Hui Vivien Koh, Robert Z. Qi, Dianbo Qu, Alirio Melendez, Jayapal Manikandan, Boon-Huat Bay, Prof Wei Duan, Dr Steve Cheung

(2006), Vol. 18, pp. 1572-1583, Cellular signalling, Amsterdam, Netherlands, C1-1

journal

Pharmacokinetic mechanisms for reduced toxicity of irinotecan by coadministered Thalidomide

Xiao-Xia Yang, Ze-Ping Hu, Sui Yung Chan, Prof Wei Duan, Paul Chi-Lui Ho, Urs Alex Boelsterli, Ka-Yun Ng, Eli Chan, Jin-Song Bian, Yu-Zong Chen, Min Huang, Shu-Feng Zhou

(2006), Vol. 7, pp. 431-454, Current drug metabolism, Hilversum, The Netherlands, C1-1

journal

Induction of propranolol metabolism by Ginkgo biloba extract EGb 761 in rats

Li-Zi Zhao, Min Huang, Jie Chen, Pui Lai Rachel Ee, Eli Chan, Prof Wei Duan, Yong-Yuna Guan, Yun-Han Hong, Xiao Chen, Shu-Feng Zhou

(2006), Vol. 7, pp. 577-587, Current drug metabolism, Hilversum, The Netherlands, C1-1

journal

Relationship between genotype and enzyme activity of glutathione S-transferases M1 and P1 in Chinese

Shilong Zhong, Shu-Feng Zhou, Xiao Chen, Sui Yung Chan, Eli Chan, Ka-Yun Ng, Prof Wei Duan, Min Huang

(2006), Vol. 28, pp. 77-85, European journal of pharmaceutical sciences, Amsterdam, The Nertherlands, C1-1

journal

Relationship of glutathione S-transferase genotypes with side-effects of pulsed cyclophsphamide therapy in patients with systemic lupus erythematosus

Shilong Zhong, Min Huang, Xiuyan Yang, Liuqin Liang, Yixi Wang, Marjorie Romkes, Prof Wei Duan, Eli Chan, Shu-Feng Zhou

(2006), Vol. 62, pp. 457-472, British journal of clinical pharmacology, London, England, C1-1

journal

Genetic polymorphisms of cytochrome P450 2B6 gene in Han Chinese

Su Guan, Min Huang, Eli Chan, Xiao Chen, Prof Wei Duan, Shu-Feng Zhou

(2006), Vol. 29, pp. 14-21, European journal of pharmaceutical sciences, Amsterdam, The Netherlands, C1-1

journal

A mechanistic study on reduced toxicity of irontecan by coadministered thalidomide, a tumor necrosis factor-a inhibitor

Xiao-Xia Yang, Ze-Ping Hu, An-Long Xu, Prof Wei Duan, Yi-Zhun Zhu, Min Huang, Fwu-Shan Sheu, Qiang Zhang, Jin-Song Bian, Eli Chan, Xiao-Tian Li, Jian-Cheng Wang, Shu-Feng Zhou

(2006), Vol. 319, pp. 82-104, Journal of pharmacology and experimental therapeutics, Bethesda, Md., C1-1

journal

Small interfering RNA-mediated silencing of cytochromeP450 3A4 gene

Jie Chen, Xiao-Xia Yang, Min Huang, Ze-Ping Hu, Ming He, Prof Wei Duan, Eli Chan, Fwu-Shan Sheu, Xiao Chen, Shu-Feng Zhou

(2006), Vol. 34, pp. 1650-1657, Drug metabolism and disposition, Bethesda, Md., C1-1

journal

A mechanistic study of the intestinal absorption of crypotanshinone, the major active constituent of Saliva miltiorrhiza

Jing Zhang, Min Huang, Su Guan, Hui-Chang Bi, Ying Pan, Prof Wei Duan, Sui Yung Chan, Xiao Chen, Yun-Han Hong, Shu-Feng Zhou

(2006), Vol. 317, pp. 1285-1294, Journal of pharmacology and experimental therapeutics, Bethesda, Md., C1-1

journal

The last 10 amino acid residues beyond the hydrophobic motif are critical for the catalytic competence and function of protein kinase Cá*

Sui Sum Yeong, Yimin Zhu, Derek Smith, Chandra Verma, Wee Guan Lim, Bee Jen Tan, A/Prof Qiu Tian Li, Dr Steve Cheung, Minnie Cai, Yi-Zhun Zhu, Shu-Feng Zhou, Seng-Lai Tan, Prof Wei Duan

(2006), Vol. 281, pp. 30768-30781, Journal of biological chemistry, Bethesda, Md, C1

journal
2005

Identification of an integral plasma membrane pool of protein kinase C in mammalian tissues and cells

Yimin Zhu, Wee Guan Lim, Bee Jen Tan, Tian-Seng Teo, Prof Wei Duan

(2005), Vol. 17, pp. 1125-1136, Cellular signalling, New York, N.Y., C1-1

journal

The PKCÁ-D294G mutant found in pituitary and thyroid tumors fails to transduce extracellular signals

Yimin Zhu, A/Prof Q Dong, Bee Jen Tan, Wee Guan Lim, Shu-Feng Zhou, Prof Wei Duan

(2005), Vol. 65, pp. 4520-4524, Cancer research, Philadelphia, Pa., C1-1

journal

Effects of purified herbal extract of Saliva miltiorrhiza on ischemic rat myocardium after acute myocardial infarction

Jian Sun, Shan Hong Huang, Benny K Tan, Matthew Whiteman, Yi Chun Zhu, Ya Jun Wu, Yeekong Ng, Prof Wei Duan, Yi-Zhun Zhu

(2005), Vol. 76, pp. 2849-2860, Life sciences, Amsterdam, The Netherlands, C1-1

journal

The last five amino acid residues at the C-terminus of PRK1 /KKN is essential for full lipid responsiveness

Wee Guan Lim, Yimin Zhu, Chern-Hoe Wang, Bee Jen Tan, Jeffrey S. Armstrong, Terje Dockland, Hongyuan Yang, Yi-Zhun Zhu, Tian-Seng Teo, Prof Wei Duan

(2005), Vol. 17, pp. 1084-1097, Cellular signalling, New York, N.Y., C1-1

journal

Prediction of herb-drug metabolic interactions: a simulation study

Shu-Feng Zhou, Min Huang, An-Long Xu, Hongyuan Yang, Prof Wei Duan, James W. Paxton

(2005), Vol. 19, pp. 464-471, Phytotherapy research: an international journal devoted to mekical and scientific research on plants and plant products, Chichester, England, C1-1

journal

Simultaneous determination of the lactone and carboxylate forms of irintecan (CPT-11) and its actie metabolite SN-38 by high-performance liquid chromatography: Application to plasma pharmacokinetic studies in the rat.

Xiao-Xia Yang, Ze-Ping Hu, Sui Yung Chan, Boon Cher Goh, Prof Wei Duan, Eli Chan, Shu-Feng Zhou

(2005), Vol. 821, pp. 221-228, Journal of chromatography. B, analytical technologies in the biomedical and life sciences, Amsterdam, The Netherlands, C1-1

journal

Molecular characterization of Osh6p, an oxysterol binding protein homolog in the yeast Saccharomyces cerevisiae

Penghua Wang, Prof Wei Duan, Alan L. Munn, Hongyuan Yang

(2005), Vol. 272, pp. 4703-4715, FEBS journal, London, England, C1-1

journal

Human multidrug resistance associated protein 4 resitance to camtothecins

Quan Tian, Jing Zhang, Theresa May Chin Tan, Eli Chan, Prof Wei Duan, Sui Yung Chan, Urs Alex Boelsterli, Paul Chi-Lui Ho, Hongyuan Yang, Jin-Song Bian, Min Huang, Yi-Zhun Zhu, Weiping Xiong, Xiao-Tian Li, Shu-Feng Zhou

(2005), Vol. 22, pp. 1837-1853, Pharmaceutical research, New York, N.Y., C1-1

journal

Influence of pulsed electromagnetic field with different pulse duty cycles on neurite outgrowth in PC12 rat pheochromocytoma cells

Yang Zhang, Jun Ding, Prof Wei Duan, W Fan

(2005), Vol. 26, pp. 406-411, Bioelectromagnetics, New York, N.Y., C1-1

journal

Alteration of the pharmacokinetics of COL-3, a matrix metalloproteinase inhibitor, due to actue gastrointestinal tosicity of doxorubicin

Jing Li, Shu-Feng Zhou, Hung Huynh, Prof Wei Duan, Eli Chan

(2005), Vol. 22, pp. 1954-1963, Pharmaceutical research, Delft, The Netherlands, C1-1

journal

Antitumor activity and underlying mechamisms of ganopoly, the refined polysaccharides extracted from ganodrema lucidum, in mice

Yihuai Gao, He Gao, Eli Chan, Wenbo Tang, An-Long Xu, Hongyuan Yang, Min Huang, Jin Ln, Xiao-Tian Li, Prof Wei Duan, Congjian xu, Shu-Feng Zhou

(2005), Vol. 34, pp. 171-198, Immunological investigations: a journal of molecular and cellular immunology, New York, N.Y., C1-1

journal

Novel agents that potentially inhibit irinotecan-induced diarrhea

Xiao-Xia Yang, Ze-Ping Hu, Sui Yung Chan, Eli Chan, Boon Cher Goh, Prof Wei Duan, Shu-Feng Zhou

(2005), Vol. 12, pp. 763-771, Current medicinal chemistry, Hilversum, The Netherlands, C1-1

journal

Insights into exazaphosphorine resistance and possible approaches to its circumvention

Jing Zhang, Quan Tian, Sui Yung Chan, Prof Wei Duan, Shu-Feng Zhou

(2005), Vol. 8, pp. 271-297, Drug resistance updates, Edinburgh, Scotland, C1-1

journal

St Johns wort modulates the toxicities and parmacokinetics of CPT-11 (Irontecan) in rats

Ze-Ping Hu, Xiao-Xia Yang, Paul Chi-Lui Ho, Eli Chan, Sui Yung Chan, Congjian xu, Xiao-Tian Li, Yi-Zhun Zhu, Prof Wei Duan, Xiao Chen, Min Huang, Hongyuan Yang, Shu-Feng Zhou

(2005), Vol. 22, pp. 902-914, Pharmaceutical research, Amsterdam, The Netherlands, C1-1

journal

Determination of thalidomide by high performance liquid chromatography: plasma pharmacokinetic studies in the rat

Xiao-Xia Yang, Ze-Ping Hu, Sui Yung Chan, Paul Chi-Lui Ho, Eli Chan, Prof Wei Duan, Boon Cher Goh, Shu-Feng Zhou

(2005), Vol. 39, pp. 299-304, Journal of pharmaceutical and biomedical analysis, Amsterdam, The Netherlands, C1-1

journal

Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs

Shu-Feng Zhou, Sui Yung Chan, Boon Cher Goh, Eli Chan, Prof Wei Duan, Min Huang, Howard L. McLeod

(2005), Vol. 44, pp. 279-304, Clinical pharmacokinetics, Auckland, New Zealand, C1-1

journal

Drug bioactivation, covalent binding to target proteins and toxicity relevance

Shu-Feng Zhou, Eli Chan, Prof Wei Duan, Min Huang, Yu-Zong Chen

(2005), Vol. 37, pp. 41-213, Drug metabolism reviews, New York, N.Y., C1-1

journal

Herb-drug interactions: a literature review

Ze-Ping Hu, Xiao-Xia Yang, Paul Chi-Lui Ho, Sui Yung Chan, Paul Wan Sia Heng, Eli Chan, Prof Wei Duan, Hwee Ling Koh, Shu-Feng Zhou

(2005), Vol. 65, pp. 1239-1282, Drugs, Auckland, New Zealand, C1-1

journal

Metabolism and transport of oxazphosphorines and the clinical implications

Jing Zhang, Quan Tian, Sui Yung Chan, Shu Chuen Li, Shu-Feng Zhou, Prof Wei Duan, Yi-Zhun Zhu

(2005), Vol. 37, pp. 611-703, Drug metabolism reviews, New York, N.Y., C1-1

journal
2004

Signaling via a novel integral plasma membrane pool of a serine/threonine protein kinase PPKI in mammalian cells

Yimin Zhu, Donna B. Stolz, Fengli Guo, Mark A. Ross, Simon C. Watkins, Bee Jen Tan, Robert Z. Qi, Ed Manser, A/Prof Qiu Tian Li, Boon-Huat Bay, Tian-Seng Teo, Prof Wei Duan

(2004), Vol. 18, pp. 1722-1724, The FASEB journal : official publication of the Federation of American Societies for experimental biology, Bethesda, Md., C1-1

journal

The influence of magnetic fields exposure on neurite outgrowth in PC12 rat pheochromocytoma cells

W Fan, Jun Ding, Prof Wei Duan, Yimin Zhu

(2004), Vol. 282, pp. 325-328, Journal of magnetism and magnetic materials, Amsterdam, The Netherlands, C1-1

journal

Cytochrome bc1 regulates the mitochondrial permeability transition by two distinct pathways

Jeffrey S. Armstrong, Hongyuan Yang, Prof Wei Duan, Matthew Whiteman

(2004), Vol. 279, pp. 50420-50428, Journal of biological chemistry, Bethesda, Md., C1-1

journal

Effects of Salvia miltiorrhiza after acute myocardial infarction in rats

Ji Xin-Yan, Benny K Tan, Shan Hong Huang, Matthew Whiteman, Yi Chun Zhu, Prof Wei Duan, Yi-Zhun Zhu, Wolfgang Linz

(2004), pp. 183-195, Novel compounds from natural products in the new millennium, Singapore, B1-1

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2002

Metallothionein 2A expression is associated with cell proliferation in breast cancer

Rongxian Jin, Vincent T.-K. Chow, Puay-Hoon Tan, S. Thameem Dheen, Prof Wei Duan, Boon-Huat Bay

(2002), Vol. 23, pp. 81-86, Carcinogenesis, Oxford, England, C1-1

journal
2001

Identification of two proteins, S14 and UIP1, that interact with UCH37

Tianwei Li, Prof Wei Duan, Hongyuan Yang, Mui-Khin Lee, Fatimah Bte Mustafa, Boon-Heng Lee, Tian-Seng Teo

(2001), Vol. 488, pp. 201-205, FEBS letters, Amsterdam, The Netherlands, C1-1

journal