Dr Damian Hernandez

Organelle mapping in dendrites of human iPSC-derived neurons reveals dynamic functional dendritic Golgi structures

Jingqi Wang, Maciej Daniszewski, Marlene Hao, Damián Hernández, Alice Pébay, Paul Gleeson, Lou Fourriere

(2023), Vol. 42, pp. 1-22, Cell Reports, Amsterdam, The Netherlands, C1

A village in a dish model system for population-scale hiPSC studies

D Neavin, A Steinmann, N Farbehi, H Chiu, M Daniszewski, H Arora, Y Bermudez, C Moutinho, C Chan, M Bax, M Tyebally, V Gnanasambandapillai, C Lam, U Nguyen, D Hernández, G Lidgerwood, R Graham, A Hewitt, A Pébay, N Palpant, J Powell

(2023), Vol. 14, pp. 1-12, Nature Communications, London, Eng., C1-1

Metergoline Shares Properties with Atypical Antipsychotic Drugs Identified by Gene Expression Signature Screen

C Bortolasci, E Jaehne, D Hernández, B Spolding, T Connor, B Panizzutti, O Dean, T Crowley, A Yung, L Gray, J Kim, M van den Buuse, M Berk, K Walder

(2023), Vol. 41, pp. 502-513, Neurotoxicity Research, C1

Microglia-like cells promote neuronal functions in cerebral organoids

I Fagerlund, A Dougalis, A Shakirzyanova, M Gómez-Budia, A Pelkonen, H Konttinen, S Ohtonen, M Fazaludeen, M Koskuvi, J Kuusisto, D Hernández, A Pebay, J Koistinaho, T Rauramaa, Š Lehtonen, P Korhonen, T Malm

(2022), Vol. 11, pp. 1-23, Cells, Basel, Switzerland, C1

Culture Variabilities of Human iPSC-Derived Cerebral Organoids Are a Major Issue for the Modelling of Phenotypes Observed in Alzheimer's Disease

D Hernández, L Rooney, M Daniszewski, L Gulluyan, H Liang, A Cook, A Hewitt, A Pébay

(2022), Vol. 18, pp. 718-731, Stem Cell Reviews and Reports, Berlin, Germany, C1

Microglial amyloid beta clearance is driven by PIEZO1 channels

H Jäntti, V Sitnikova, Y Ishchenko, A Shakirzyanova, L Giudice, I Ugidos, M Gómez-Budia, N Korvenlaita, S Ohtonen, I Belaya, F Fazaludeen, N Mikhailov, M Gotkiewicz, K Ketola, Š Lehtonen, J Koistinaho, K Kanninen, D Hernández, A Pébay, R Giugno, P Korhonen, R Giniatullin, T Malm

(2022), Vol. 19, Journal of Neuroinflammation, England, C1-1

Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration

A Senabouth, M Daniszewski, G Lidgerwood, H Liang, D Hernández, M Mirzaei, S Keenan, R Zhang, X Han, D Neavin, L Rooney, M Lopez Sanchez, L Gulluyan, J Paulo, L Clarke, L Kearns, V Gnanasambandapillai, C Chan, U Nguyen, A Steinmann, R McCloy, N Farbehi, V Gupta, D Mackey, G Bylsma, N Verma, S MacGregor, M Watt, R Guymer, J Powell, A Hewitt, A Pébay

(2022), Vol. 13, Nature Communications, England, C1-1

Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma

M Daniszewski, A Senabouth, H Liang, X Han, G Lidgerwood, D Hernández, P Sivakumaran, J Clarke, S Lim, J Lees, L Rooney, L Gulluyan, E Souzeau, S Graham, C Chan, U Nguyen, N Farbehi, V Gnanasambandapillai, R McCloy, L Clarke, L Kearns, D Mackey, J Craig, S MacGregor, J Powell, A Pébay, A Hewitt

(2022), Vol. 2, pp. 1-20, Cell Genomics, Amsterdam, The Netherlands, C1

A sporadic Alzheimer's blood-brain barrier model for developing ultrasound-mediated delivery of Aducanumab and anti-Tau antibodies

J Wasielewska, J Chaves, R Johnston, L Milton, D Hernández, L Chen, J Song, W Lee, G Leinenga, R Nisbet, A Pébay, J Götz, A White, L Oikari

(2022), Vol. 12, pp. 6826-6847, Theranostics, Wyoming, N.S.W., C1-1

Generation of a gene-corrected human isogenic iPSC line from an Alzheimer's disease iPSC line carrying the London mutation in APP (V717I)

D Hernández, S Morgan Schlicht, M Daniszewski, C Karch, A Goate, A Pébay

(2021), Vol. 53, Stem Cell Research, England, C1

Automation of Organoid Cultures: Current Protocols and Applications

A Louey, D Hernández, A Pébay, M Daniszewski

(2021), Vol. 26, pp. 1138-1147, SLAS Discovery, United States, C1

Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells

D Neavin, Q Nguyen, M Daniszewski, H Liang, H Chiu, Y Wee, A Senabouth, S Lukowski, D Crombie, G Lidgerwood, D Hernández, J Vickers, A Cook, N Palpant, A Pébay, A Hewitt, J Powell

(2021), Vol. 22, Genome Biology, England, C1

A Tissue Engineering Chamber for Continuous Pulsatile Electrical Stimulation of Vascularized Cardiac Tissues in Vivo

D Hernández, R Millard, A Kong, O Burns, P Sivakumaran, R Shepherd, G Dusting, S Lim

(2020), Vol. 2, pp. 391-398, Bioelectricity, United States, C1

If Human Brain Organoids Are the Answer to Understanding Dementia, What Are the Questions?

L Ooi, M Dottori, A Cook, M Engel, V Gautam, A Grubman, D Hernández, A King, S Maksour, H Targa Dias Anastacio, R Balez, A Pébay, C Pouton, M Valenzuela, A White, R Williamson

(2020), Vol. 26, pp. 438-454, Neuroscientist, United States, C1

A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-Derived Basal Forebrain-Like Cholinergic Neurons for Alzheimer's Disease and Frontotemporal Dementia Disease Modeling

S Muñoz, M Engel, R Balez, D Do-Ha, M Cabral-da-Silva, D Hernández, T Berg, J Fifita, N Grima, S Yang, I Blair, G Nicholson, A Cook, A Hewitt, A Pébay, L Ooi

(2020), Vol. 9, Cells, Switzerland, C1

PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia

H Konttinen, M Cabral-da-Silva, S Ohtonen, S Wojciechowski, A Shakirzyanova, S Caligola, R Giugno, Y Ishchenko, D Hernández, M Fazaludeen, S Eamen, M Budia, I Fagerlund, F Scoyni, P Korhonen, N Huber, A Haapasalo, A Hewitt, J Vickers, G Smith, M Oksanen, C Graff, K Kanninen, S Lehtonen, N Propson, M Schwartz, A Pébay, J Koistinaho, L Ooi, T Malm

(2019), Vol. 13, pp. 669-683, Stem Cell Reports, United States, C1

Mitochondrial Fusion by M1 Promotes Embryoid Body Cardiac Differentiation of Human Pluripotent Stem Cells

J Lees, A Kong, Y Chen, P Sivakumaran, D Hernández, A Pébay, A Harvey, D Gardner, S Lim

(2019), Vol. 2019, Stem Cells International, United States, C1

Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network

C Karch, D Hernández, J Wang, J Marsh, A Hewitt, S Hsu, J Norton, D Levitch, T Donahue, W Sigurdson, B Ghetti, M Farlow, J Chhatwal, S Berman, C Cruchaga, J Morris, R Bateman, A Pébay, A Goate

(2018), Vol. 10, Alzheimer's Research and Therapy, England, C1

Role of lysophosphatidic acid in the retinal pigment epithelium and photoreceptors

G Lidgerwood, A Morris, A Conquest, M Daniszewski, L Rooney, S Lim, D Hernández, H Liang, P Allen, P Connell, R Guymer, A Hewitt, A Pébay

(2018), Vol. 1863, pp. 750-761, Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Netherlands, C1

Single-Cell Profiling Identifies Key Pathways Expressed by iPSCs Cultured in Different Commercial Media

M Daniszewski, Q Nguyen, H Chy, V Singh, D Crombie, T Kulkarni, H Liang, P Sivakumaran, G Lidgerwood, D Hernández, A Conquest, L Rooney, S Chevalier, S Andersen, A Senabouth, J Vickers, D Mackey, J Craig, A Laslett, A Hewitt, J Powell, A Pébay

(2018), Vol. 7, pp. 30-39, iScience, United States, C1

Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells

A Hoque, P Sivakumaran, S Bond, N Ling, A Kong, J Scott, N Bandara, D Hernández, G Liu, R Wong, M Ryan, D Hausenloy, B Kemp, J Oakhill, B Drew, A Pébay, S Lim

(2018), Vol. 4, Cell Death Discovery, United States, C1

Biologically active constituents of the secretome of human W8B2⁺ cardiac stem cells

S Nie, X Wang, P Sivakumaran, M Chong, X Liu, T Karnezis, N Bandara, K Takov, C Nowell, S Wilcox, M Shambrook, A Hill, N Harris, A Newcomb, P Strappe, R Shayan, D Hernández, J Clarke, E Hanssen, S Davidson, G Dusting, A Pébay, J Ho, N Williamson, S Lim

(2018), Vol. 8, Scientific Reports, England, C1

Development of a Modular Automated System for Maintenance and Differentiation of Adherent Human Pluripotent Stem Cells

D Crombie, M Daniszewski, H Liang, T Kulkarni, F Li, G Lidgerwood, A Conquest, D Hernández, S Hung, K Gill, E De Smit, L Kearns, L Clarke, V Sluch, X Chamling, D Zack, R Wong, A Hewitt, A Pébay

(2017), Vol. 22, pp. 1016-1025, SLAS Discovery, United States, C1

Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells

S Hung, N Van Bergen, S Jackson, H Liang, D Mackey, D Hernández, S Lim, A Hewitt, I Trounce, A Pébay, R Wong

(2016), Vol. 8, pp. 945-957, Aging, United States, C1

Defined Medium Conditions for the Induction and Expansion of Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium

G Lidgerwood, S Lim, D Crombie, R Ali, K Gill, D Hernández, J Kie, A Conquest, H Waugh, R Wong, H Liang, A Hewitt, K Davidson, A Pébay

(2016), Vol. 12, pp. 179-188, Stem Cell Reviews and Reports, United States, C1

Electrical stimulation promotes cardiac differentiation of human induced pluripotent stem cells

D Hernández, R Millard, P Sivakumaran, R Wong, D Crombie, A Hewitt, H Liang, S Hung, A Pébay, R Shepherd, G Dusting, S Lim

(2016), Vol. 2016, Stem Cells International, United States, C1

Cardiac Repair with a Novel Population of Mesenchymal Stem Cells Resident in the Human Heart

Y Zhang, P Sivakumaran, A Newcomb, D Hernandez, N Harris, R Khanabdali, G Liu, D Kelly, A Pébay, A Hewitt, A Boyle, R Harvey, W Morrison, D Elliott, G Dusting, S Lim

(2015), Vol. 33, pp. 3100-3113, Stem Cells, England, C1-1

Growing vascularized heart tissue from stem cells

S Lim, D Hernández, G Dusting

(2013), Vol. 62, pp. 122-129, Journal of Cardiovascular Pharmacology, United States, C1-1

A single residue in transmembrane domain 11 defines the different affinity for thiazides between the mammalian and flounder NaCl transporters

M Castañeda-Bueno, N Vázquez, I Bustos-Jaimes, D Hernández, E Rodríguez-Lobato, D Pacheco-Alvarez, R Cariño-Cortés, E Moreno, N Bobadilla, G Gamba

(2010), Vol. 299, pp. F1111-F1119, American Journal of Physiology - Renal Physiology, United States, C1-1

Radicicol, a heat shock protein 90 inhibitor, reduces glomerular filtration rate

V Ramírez, J Mejía-Vilet, D Hernández, G Gamba, N Bobadilla

(2008), Vol. 295, pp. F1044-F1051, American Journal of Physiology - Renal Physiology, United States, C1-1

CEBPG regulates ERCC5/XPG expression in human bronchial epithelial cells and this regulation is modified by E2F1/YY1 interactions

E Crawford, T Blomquist, D Mullins, Y Yoon, D Hernandez, M Al-Bagdhadi, J Ruiz, J Hammersley, J Willey

(2007), Vol. 28, pp. 2552-2559, Carcinogenesis, England, C1-1