Dr Damien Callahan

STAFF PROFILE

Position

Senior Lecturer in Chemistry

Faculty

Faculty of Sci Eng & Built Env

Department

School of Life & Env. Sciences

Campus

Melbourne Burwood Campus

Qualifications

Graduate Certificate in University Teaching, University of Melbourne, 2012
Doctor of Philosophy, University of Melbourne, 2007

Contact

Biography

Dr Damien Callahan is currently a Chemistry lecturer in the School of Life and Environmental Sciences at Deakin University (Melbourne, Australia) and also holds and honorary position in the School of Botany at The University of Melbourne. His primary areas of research are in LC-MS method development in Metabolomics, applied research on metal hyperaccumulating plants and microalgal lipid biochemistry in the Centre for chemistry and Biotechnology at Deakin University. He has more than 15 years of experience in analytical chemistry in both industry and academic environments. His research has advanced the methodology used for small molecule and lipid analysis in the rapidly progressing field of metabolomics. The development of new analytical techniques for small molecule and lipid analysis was the major focus his recent postdoctoral research career where he made significant contributions to the development of the world leading Metabolomics research facilities of Metabolomics Australia. The methodology he developed while working in metabolite profiling has been applied to large number of fields, in particular metal hyperaccumulating plants, as well as diabetes research, algae biofuels, fungal secondary metabolites, plant taxonomy and plant and fungal mineral nutrition.

Read more on Damien's profile

Units taught

SLE133, SLE155

Knowledge areas

Metabolomics/Lipidomics

Liquid Chromatography Mass spectrometry

Analytical Chemistry

Metal hyperaccumulating plants/phytoremediation

Algal lipid biochemistry/biofuels

Awards

The Royal Australian Chemical Institute (RACI) C.S. Piper prize (November 2010), given for the best published research in Australia on either soil chemistry or the mineral nutrition of plants

Publications

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2020

The effects of early-onset pre-eclampsia on placental creatine metabolism in the third trimester

S Ellery, P Murthi, P Gatta, A May, M Davies-Tuck, G Kowalski, D Callahan, C Bruce, E Wallace, D Walker, H Dickinson, R Snow

(2020), Vol. 21, pp. 1-14, International journal of molecular sciences, Basel, Switzerland, C1

journal
2019

UNICORN babies: understanding circulating and cerebral creatine levels of the preterm infant. An observational study protocol

Mary Berry, Melissa Schlegel, Greg Kowalski, Clinton Bruce, Damien Callahan, Miranda Davies-Tuck, Hayley Dickinson, Angus Goodson, Angie Slocombe, Rod Snow, David Walker, Stacey Ellery

(2019), Vol. 10, pp. 1-8, Frontiers in physiology, Lausanne, Switzerland, C1

journal

Phosphatidylserine decarboxylase is critical for the maintenance of skeletal muscle mitochondrial integrity and muscle mass

A Selathurai, G Kowalski, S Mason, D Callahan, V Foletta, P Della Gatta, A Lindsay, S Hamley, G Kaur, A Curtis, M Burch, T Ang, S McGee, C Bruce

(2019), Vol. 27, pp. 33-46, Molecular metabolism, Amsterdam, The Netherlands, C1

journal

Combining evolutionary inference and metabolomics to identify plants with medicinal potential

Sundara Mawalagedera, Damien Callahan, Anne Gaskett, Nina Rnsted, Matthew Symonds

(2019), Vol. 7, pp. 1-11, Frontiers in ecology and evolution, Lausanne, Switzerland, C1

journal

Placental creatine metabolism in cases of placental insufficiency and reduced fetal growth

Stacey Ellery, Padma Murthi, Miranda Davies-Tuck, Paul Della Gatta, Anthony May, Greg Kowalski, Damien Callahan, Clinton Bruce, Nicole Alers, Suzanne Miller, Jan Erwich, Euan Wallace, David Walker, Hayley Dickinson, Rod Snow

(2019), Vol. 25, pp. 495-505, Molecular human reproduction, Oxford, Eng., C1

journal

Metabolic engineering of bread wheat improves grain iron concentration and bioavailability

J Beasley, J Bonneau, J Snchez-Palacios, L Moreno-Moyano, D Callahan, E Tako, R Glahn, E Lombi, A Johnson

(2019), Vol. 17, pp. 1514-1526, Plant biotechnology journal, Chichester, Eng., C1

journal

Blubber fatty acids reveal variation in the diet of male Australian fur seals

T Knox, D Callahan, L Kernalguen, A Baylis, J Arnould

(2019), Vol. 166, pp. 1-11, Marine Biology, Berlin, Germany, C1

journal

Spatio-temporal metabolite and elemental profiling of salt stressed barley seeds during initial stages of germination by MALDI-MSI and -XRF spectrometry

S Gupta, T Rupasinghe, D Callahan, S Natera, P Smith, C Hill, U Roessner, B Boughton

(2019), Vol. 10, pp. 1-17, Frontiers in Plant Science, Lausanne, Switzerland, C1

journal

Comparative spatial lipidomics analysis reveals cellular lipid remodelling in different developmental zones of barley roots in response to salinity

L Sarabia, B Boughton, T Rupasinghe, D Callahan, C Hill, U Roessner

(2019), pp. 1-17, Plant, cell and environment, Chichester, Eng., C1

journal
2018

Comparative metabolic and ionomic profiling of two cultivars of Stevia rebaudiana Bert. (Bertoni) grown under salinity stress

M Debnath, N Ashwath, C Hill, D Callahan, D Dias, N Jayasinghe, D Midmore, U Roessner

(2018), Vol. 129, pp. 56-70, Plant physiology and biochemistry, Amsterdam, The Netherlands, C1

journal

High-mass-resolution MALDI mass spectrometry imaging reveals detailed spatial distribution of metabolites and lipids in roots of barley seedlings in response to salinity stress

L Sarabia, B Boughton, T Rupasinghe, A van de Meene, D Callahan, C Hill, U Roessner

(2018), Vol. 14, pp. 1-16, Metabolomics, New York, N.Y., C1

journal

Rapid induction of vitamin B12 deficiency in Caenorhabditis elegans cultured in axenic medium

S Tegegne, M Jois, M Flavel, D Callahan, D Benheim

(2018), Vol. 13, pp. 20-25, Journal of nutrition and intermediary metabolism, Amsterdam, The Netherlands, C1

journal

Detection of endogenous phosphatidylinositol 4,5-bisphosphate in phytophthora cinnamomi

Jeff Howard, Peter Beech, Damien Callahan

(2018), Vol. 53, pp. 835-839, Lipids, Chichester, Eng., C1

journal
2017

A quantitative profiling method of phytohormones and other metabolites applied to barley roots subjected to salinity stress

D Cao, A Lutz, C Hill, D Callahan, U Roessner

(2017), Vol. 7, pp. 1-19, Frontiers in plant science, Lausanne, Switzerland, C1

journal

Nickel biopathways in tropical nickel hyperaccumulating trees from Sabah (Malaysia)

A Van Der Ent, D Callahan, B Noller, J Mesjasz-Przybylowicz, W Przybylowicz, A Barnabas, H Harris

(2017), Vol. 7, pp. 1-21, Scientific reports, London, Eng., C1

journal

Global fecal and plasma metabolic dynamics related to Helicobacter pylori eradication

T Yap, A Leow, A Azmi, D Callahan, G Perez-Perez, M Loke, K Goh, J Vadivelu

(2017), Vol. 8, pp. 1-22, Frontiers in microbiology, Lausanne, Switzerland, C1

journal

Prospection and identification of nematotoxic compounds from Canavalia ensiformis seeds effective in the control of the root knot nematode Meloidogyne incognita

Thales Rocha, Carla Soll, Berin Boughton, Tiago Silva, Klaus Oldach, Alexandre Firmino, Damien Callahan, John Sheedy, Edilberto Silveira, Regina Carneiro, Luciano Silva, Vera Polez, Patrcia Pelegrini, Antony Bacic, Maria Grossi-de-Sa, Ute Roessner

(2017), Vol. 1, pp. 87-100, Biotechnology research and innovation, Amsterdam, The Netherlands, C1

journal
2016

Elemental imaging of leaves from the metal hyperaccumulating plant Noccaea caerulescens shows different spatial distribution of Ni, Zn and Cd

D Callahan, D Hare, D Bishop, P Doble, U Roessner

(2016), Vol. 6, pp. 2337-2344, RSC advances, Cambridge, Eng., C1

journal

Metal and metalloid containing natural products and a brief overview of their applications in biology, biotechnology and biomedicine

D Dias, K Kouremenos, D Beale, D Callahan, O Jones

(2016), Vol. 29, pp. 1-13, Biometals, Berlin, Germany, C1

journal

Apicoplast-localized lysophosphatidic acid precursor assembly is required for bulk phospholipid synthesis in toxoplasma gondii and relies on an algal/plant-like glycerol 3-phosphate acyltransferase

S Amiar, J MacRae, D Callahan, D Dubois, G van Dooren, M Shears, M Cesbron-Delauw, E Marchal, M McConville, G McFadden, Y Yamaryo-Bott, C Bott

(2016), Vol. 12, pp. 1-30, PLoS pathogens, San Francisco, Calif., C1

journal

Strategies for extending metabolomics studies with stable isotope labelling and fluxomics

A Srivastava, G Kowalski, D Callahan, P Meikle, D Creek

(2016), Vol. 6, pp. 1-13, Metabolites, Basel, Switzerland, C1

journal

Reduced triacylglycerol mobilization during seed germination and early seedling growth in Arabidopsis containing nutritionally important polyunsaturated fatty acids

P Shrestha, D Callahan, S Singh, J Petrie, X Zhou

(2016), Vol. 7, pp. 1-15, Frontiers in Plant Science, Lausanne, Switzerland, C1

journal

A simple method for measuring carbon-13 fatty acid enrichment in the major lipid classes of microalgae using GC-MS

S Elahee Doomun, S Loke, S O'Callaghan, D Callahan

(2016), Vol. 6, pp. 1-13, Metabolites, Basel, Switzerland, C1

journal
2015

The use of metabolomics in the study of metals in biological systems

O Jones, D Dias, D Callahan, K Kouremenos, D Beale, U Roessner

(2015), Vol. 7, pp. 29-38, Metallomics, Cambridge, Eng., C1

journal

A tandem liquid chromatography-mass spectrometry (LC-MS) method for profiling small molecules in complex samples

J Pyke, D Callahan, K Kanojia, J Bowne, S Sahani, D Tull, A Bacic, M McConville, U Roessner

(2015), Vol. 11, pp. 1552-1562, Metabolomics, Berlin, Germany, C1

journal

Analytical approaches towards the characterization of algal lipid extracts for the production of biodiesel

D Callahan, G Martin, D Hill, I Olmstead, D Dias

(2015), Vol. 1, pp. 331-346, Marine algae extracts : processes, products and applications, London, Eng., B1

chapter

LC-MS data acquisition and validation in metabolomics

D Callahan

(2015), pp. 20-34, Identification and data processing methods in metabolomics, London, Eng., B1

chapter
2014

Hyperaccumulation of zinc by Noccaea caerulescens results in a cascade of stress responses and changes in the elemental profile

S Foroughi, A Baker, U Roessner, A Johnson, A Bacic, D Callahan

(2014), Vol. 6, pp. 1671-1682, Metallomics, Cambridge, England, C1

journal

Lipidomic analysis of Arabidopsis seed genetically engineered to contain DHA

X-R Zhou, D Callahan, P Shrestha, Q Liu, J Petrie, S Singh

(2014), Vol. 5, pp. 1-12, Frontiers in plant science, Lausanne, Switzerland, C1

journal

Lipid Profile Remodeling in Response to Nitrogen Deprivation in the Microalgae Chlorella sp. (Trebouxiophyceae) and Nannochloropsis sp. (Eustigmatophyceae)

Gregory Martin, David Hill, Ian Olmstead, Amanda Bergamin, Melanie Shears, Daniel Dias, Sandra Kentish, Peter Scales, Cyrille Bott, Damien Callahan

(2014), Vol. 9, pp. 1-10, PLoS ONE, San Francisco, CA, C1

journal

The reducing end sequence of wheat endosperm cell wall arabinoxylans

Sunil Ratnayake, Cherie Beahan, Damien Callahan, Antony Bacic

(2014), Vol. 386, pp. 23-32, Carbohydrate Research, Doetinchem, Netherlands, C1-1

journal

Testing the boundaries of closely related daisy taxa using metabolomic profiling

A Messina, D Callahan, N Walsh, S Hoebee, P Green

(2014), Vol. 63, pp. 367-376, Taxon, Utrecht, The Netherlands, C1-1

journal
2013

A gene cluster responsible for biosynthesis of phomenoic acid in the plant pathogenic fungus, Leptosphaeria maculans

C Elliott, D Callahan, D Schwenk, M Nett, D Hoffmeister, B Howlett

(2013), Vol. 53, pp. 50-58, Fungal Genetics and Biology, C1-1

journal

Chemical characterisation and speciation of organic selenium in cultivated selenium-enriched Agaricus bisporus

T Maseko, D Callahan, F Dunshea, A Doronila, S Kolev, K Ng

(2013), Vol. 141, pp. 3681-3687, Food Chemistry, C1-1

journal

A quantitative analysis of microalgal lipids for optimization of biodiesel and omega-3 production

I Olmstead, D Hill, D Dias, N Jayasinghe, D Callahan, S Kentish, P Scales, G Martin

(2013), Vol. 110, pp. 2096-2104, Biotechnology and Bioengineering, C1-1

journal

A workflow from untargeted LC-MS profiling to targeted natural product isolation

D Callahan, C Elliott

(2013), Vol. 1055, pp. 57-70, Methods in Molecular Biology, B1-1

chapter

Cross-Platform Urine Metabolomics of Experimental Hyperglycemia in Type 2 Diabetes

Liesbet Temmerman

(2013), Vol. 01, Journal of Diabetes & Metabolism, C1-1

journal
2012

Elemental and metabolite profiling of nickel hyperaccumulators from New Caledonia

D Callahan, U Roessner, V Dumontet, A De Livera, A Doronila, A Baker, S Kolev

(2012), Vol. 81, pp. 80-89, Phytochemistry, Amsterdam, The Netherlands, C1-1

journal

Randomized controlled study of the urinary excretion of biophenols following acute and chronic intake of olive leaf supplements

M Kendall, M Batterham, D Callahan, D Jardine, P Prenzler, K Robards, D Ryan

(2012), Vol. 130, pp. 651-659, Food chemistry, Amsterdam, The Netherlands, C1-1

journal

Arsenic response in roots of Eucalyptus spp.

J Sanchez-Palacios, D Callahan, A Baker, I Woodrow, A Doronila, Y Wang, R Collins

(2012), pp. 332-334, As 2012 : Understanding the geological medical interface of arsenic : Proceedings of the 4th International Congress: Arsenic in the Environment, Cairns, Qld., E1-1

conference
2011

Comprehensive profiling and quantitation of amine group containing metabolites

B Boughton, D Callahan, C Silva, J Bowne, A Nahid, T Rupasinghe, D Tull, M McConville, A Bacic, U Roessner

(2011), Vol. 83, pp. 7523-7530, Analytical chemistry, Washington, D.C., C1-1

journal

Constitutive overexpression of the OsNAS gene family reveals single-gene strategies for effective iron- and zinc-biofortification of rice endosperm

A Johnson, B Kyriacou, D Callahan, L Carruthers, J Stangoulis, E Lombi, M Tester

(2011), Vol. 6, pp. 1-11, PLoS one, San Francisco, Calif., C1-1

journal
2009

Metabolite profiling of biological extracts

D Callahan, A Bacic, U Roessner

(2009), pp. 1-1, ANZSMS 2009: 22nd Conference of the Australian and New Zealand Society for Mass Spectrometry 2009, Sydney, NSW, E1-1

conference

Functional genomic analysis of systemic cell division regulation in legumes

P Gresshoff, A Indrasumunar, A Miyahara, S Nontachaiyapoom, B Biswas, Y-H Lin, M-H Lin, D Reid, D Callahan, R Capon, Q Zhang, H Zhang, T Hirani, B Kobe, A Men, P Scott, A Kereszt, M Miyagi, D Li, P-K Chan, U Roessner, M Djordjevic, M Kinkema, B Ferguson

(2009), pp. 399-402, Induced Plant Mutations in the Genomics Era. Food and Agriculture Organization of the United Nations, Rome, Vienna, Austria, E1-1

conference

Profiling of polar metabolites in biological extracts using diamond hydride-based aqueous normal phase chromatography

D Callahan, D Souza, A Bacic, U Roessner

(2009), Vol. 32, pp. 2273-2280, Journal of separation science, Londn, Eng., C1-1

journal

Competition between cluster fragmentation, C-C bond coupling and C-X bond activation in silver hexynyl cluster cations, [(C4H9CCAg)nAg]+. Size does matter!

F Wang, G Khairallah, G Koutsantonis, C Williams, D Callahan, R O?Hair

(2009), Vol. 11, pp. 1-4, Physical chemistry chemical physics, London, Eng., C1-1

journal
2008

Metabolite profiling reveals distinct changes in carbon and nitrogen metabolism in phosphate-deficient barley plants (Hordeum vulgare L.)

C Huang, U Roessner, I Eickmeier, Y Genc, D Callahan, N Shirley, P Langridge, A Bacic

(2008), Vol. 49, pp. 691-703, Plant and cell physiology, Oxford, Eng., C1-1

journal

LC-MS and GC-MS metabolite profiling of nickel(II) complexes in the latex of the nickel-hyperaccumulating tree Sebertia acuminata and identification of methylated aldaric acid as a new nickel(II) ligand

D Callahan, U Roessner, V Dumontet, N Perrier, A Wedd, R O?Hair, A Baker, S Kolev

(2008), Vol. 69, pp. 240-251, Phytochemistry, Amsterdam, The Netherlands, C1-1

journal
2007

Relationships of nicotianamine and other amino acids with nickel, zinc and iron in Thlaspi hyperaccumulators

D Callahan, S Kolev, R O?Hair, D Salt, A Baker

(2007), Vol. 176, pp. 836-848, New phytologist, London, Eng., C1-1

journal
2006

Metal ion ligands in hyperaccumulating plants

D Callahan, A Baker, S Kolev, A Wedd

(2006), Vol. 11, pp. 2-12, JBIC journal of biological inorganic chemistry, Berlin, Germany, C1-1

journal
2005

Systematic approach to the quantitative voltammetric analysis of the Fe III /Fe II component of the [? 2 -Fe(OH 2 )P 2 W 17 O 61 ] 7-/8- reduction process in buffered and unbuffered aqueous media

S-X Guo, S Feldberg, A Bond, D Callahan, P Richardt, A Wedd

(2005), Vol. 109, pp. 20641-20651, Journal of physical chemistry B, Washington, D.C., C1-1

journal

Funded Projects at Deakin

Australian Competitive Grants

Enhancing the flavour of farmed fish through dietary innovation

A/Prof David Francis, Prof Giovanni Turchini, Rocky De Nys, Dr Damien Callahan, A/Prof Xavier Conlan, Prof Russell Keast, Vittorio Moretti, Dr Richard Smullen, Susan Poole

ARC Linkage - Projects

  • 2020: $25,740
  • 2019: $120,756
  • 2018: $50,706

Hydrogen: an overlooked intermediate during anoxia in permeable sediments

Dr Perran Cook, Christopher Greening, Dr Damien Callahan

ARC - Discovery Projects

  • 2019: $7,000
  • 2018: $7,000

Holistic Remediation of PFAS-affected Soils, Waters and Debris

Dr Will Gates, Prof Frank Collins, Dr Damien Callahan, Mr Jonathan Miller, Mr Anish Chandy

ARC Special Research Initiatives

  • 2020: $67,473
  • 2019: $433,072
  • 2018: $457,282

Industry and Other Funding

Enhancing the flavour of farmed fish through dietary innovation

A/Prof David Francis, Prof Giovanni Turchini, Rocky De Nys, Dr Damien Callahan, A/Prof Xavier Conlan, Prof Russell Keast, Vittorio Moretti, Dr Richard Smullen, Susan Poole

  • 2019: $50,000

Holistic Remediation of PFAS-affected Soils, Waters and Debris

Dr Will Gates, Prof Frank Collins, Dr Damien Callahan, Mr Jonathan Miller, Mr Anish Chandy

  • 2019: $50,000

Nutritional composition of cultured kelps and influences of sample preservation.

Dr Alecia Bellgrove, Miss Vanessa Skrzypczyk, Dr Damien Callahan, A/Prof David Francis

  • 2019: $11,000

Bioaccumulative contaminants and nanoplastics in Australian fur seals

Prof John Arnould, Dr Damien Callahan, Ms Cassie Nettina Speakman

  • 2020: $19,230

Supervisions

Associate Supervisor
2019

Sundara Mudiyanselage Udayanga Mawalagedera

Thesis entitled: A Phylogenetic and Metabolomic Approach to Identify Medicinal Potential in Australasian Magnoliids

Doctor of Philosophy (Life & Env), School of Life and Environmental Sciences

Lawrence Webb

Thesis entitled: Exploring tropane alkaloid production in Australian Duboisia plantations

Doctor of Philosophy (Biol & Chem), School of Life and Environmental Sciences