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A/Prof. Laura Gray

STAFF PROFILE

Position

Associate Professor

Faculty

Faculty of Health

Department

School of Medicine

Campus

Geelong Waurn Ponds Campus

Contact

l.gray@deakin.edu.au
+61 3 522 72852

Publications

Filter by

2022

Co-Expression Networks Unveiled Long Non-Coding RNAs as Molecular Targets of Drugs Used to Treat Bipolar Disorder

Trang Truong, Chiara Bortolasci, Briana Spolding, Bruna Panizzutti, Zoe Liu, Srisaiyini Kidnapillai, Mark Richardson, Laura Gray, Craig Smith, Olivia Dean, Jee Kim, Michael Berk, Ken Walder

(2022), Vol. 13, pp. 1-12, Frontiers in Pharmacology, Lausanne, Switzerland, C1

journal article
2021

Effects of psychoactive drugs on cellular bioenergetic pathways

C Bortolasci, B Spolding, S Kidnapillai, M Richardson, N Vasilijevic, S Martin, L Gray, S McGee, M Berk, K Walder

(2021), Vol. 22, pp. 79-93, World Journal of Biological Psychiatry, England, C1

journal article

Differential level of RXFP3 expression in dopaminergic neurons within the arcuate nucleus, dorsomedial hypothalamus and ventral tegmental area of RXFP3-Cre/tdTomato mice

L Voglsanger, J Read, S Ch’ng, C Zhang, I Eraslan, L Gray, L Rivera, L Hamilton, R Williams, A Gundlach, C Smith

(2021), Vol. 14, pp. 1-10, Frontiers in neuroscience, Lausanne, Switzerland, C1

journal article

Transcriptional modulation of the hippo signaling pathway by drugs used to treat bipolar disorder and schizophrenia

B Panizzutti, C Bortolasci, B Spolding, S Kidnapillai, T Connor, M Richardson, T Truong, Z Liu, G Morris, L Gray, J Kim, O Dean, M Berk, K Walder

(2021), Vol. 22, pp. 1-16, International Journal of Molecular Sciences, Basel, Switzerland, C1

journal article

Baseline serum amino acid levels predict treatment response to augmentation with N-acetylcysteine (NAC) in a bipolar disorder randomised trial

C Bortolasci, A Turner, M Mohebbi, Z Liu, M Ashton, L Gray, W Marx, A Walker, G Kowalski, F Jacka, M Berk, O Dean, K Walder

(2021), Vol. 142, pp. 376-383, Journal of Psychiatric Research, Amsterdam, The Netherlands, C1

journal article

Biological mechanism(S) underpinning the association between antipsychotic drugs and weight gain

B Panizzutti, C Bortolasci, B Spolding, S Kidnapillai, T Connor, M Richardson, T Truong, Z Liu, L Gray, J Kim, O Dean, M Berk, K Walder

(2021), Vol. 10, pp. 1-8, Journal of Clinical Medicine, Basel, Switzerland, C1

journal article

Exploring interleukin-6, lipopolysaccharide binding protein and brain-derived neurotrophic factor following 12 weeks of adjunctive minocycline treatment for depression

K Hasebe, M Mohebbi, L Gray, A Walker, C Bortolasci, A Turner, M Berk, K Walder, M Maes, B Kanchanatawan, M Ashton, L Berk, C Ng, G Malhi, A Singh, O Dean

(2021), pp. 1-8, Acta Neuropsychiatrica, Cambridge, Eng., C1

journal article
2020

The use of a gene expression signature and connectivity map to repurpose drugs for bipolar disorder

S Kidnapillai, C Bortolasci, M Udawela, B Panizzutti, B Spolding, T Connor, A Sanigorski, O Dean, T Crowley, S Jamain, L Gray, E Scarr, M Leboyer, B Dean, M Berk, K Walder

(2020), Vol. 21, pp. 775-783, World Journal of Biological Psychiatry, England, C1

journal article

Drugs used to treat bipolar disorder act via microRNAs to regulate expression of genes involved in neurite outgrowth

S Kidnapillai, B Wade, C Bortolasci, B Panizzutti, B Spolding, T Connor, T Crowley, S Jamain, L Gray, M Leboyer, M Berk, K Walder

(2020), Vol. 34, pp. 370-379, Journal of psychopharmacology, London, Eng., C1

journal article

Minocycline for the treatment of mental health and neurological conditions: study protocol of a systematic review and meta-analysis

C Bortolasci, W Marx, A Walker, K Hasebe, B Kavanagh, M Morris, M Mohebbi, A Turner, L Gray, L Berk, K Walder, M Berk, O Dean

(2020), Vol. 10, pp. 1-4, BMJ open, London, Eng., C1

journal article

Interleukin-6 and total antioxidant capacity levels following N-acetylcysteine and a combination nutraceutical intervention in a randomised controlled trial for bipolar disorder

C Bortolasci, C Voigt, A Turner, M Mohebbi, L Gray, S Dodd, K Walder, M Berk, S Cotton, G Malhi, C Ng, N Dowling, J Sarris, O Dean

(2020), Vol. 32, pp. 313-320, Acta Neuropsychiatrica, Cambridge, Eng., C1

journal article

Transcriptional effects of psychoactive drugs on genes involved in neurogenesis

Chiara Bortolasci, Briana Randall, Srisaiyini Kidnapillai, Timothy Connor, Trang Truong, Z Liu, Bruna Panizzutti Parry, Mark Richardson, Laura Gray, Michael Berk, Olivia Dean, Ken Walder

(2020), Vol. 21, International Journal of Molecular Sciences, Basel, Switzerland, C1

journal article
2019

Phenotyping neurons activated in the mouse brain during restoration of salt debt

Craig Smith, Joshua Cross, Izel Eraslan, Aparna Attawar, Sarah Ch’ng, Poshmaal Dhar, Rasika Samarasinghe, Laura Gray, Andrew Lawrence

(2019), Vol. 101, pp. 1-9, Journal of chemical neuroanatomy, Amsterdam, The Netherlands, C1

journal article

Modulation of high fat diet-induced microbiome changes, but not behaviour, by minocycline

K Hasebe, L Rivera, C Smith, T Allnutt, T Crowley, T Nelson, O Dean, S McGee, K Walder, L Gray

(2019), Vol. 82, pp. 309-318, Brain, behavior, and immunity, Amsterdam, The Netherlands, C1

journal article

Drugs used in the treatment of bipolar disorder and their effects on cholesterol biosynthesis - a possible therapeutic mechanism

S Kidnapillai, C Bortolasci, B Panizzutti, B Spolding, T Connor, K Bonifacio, A Sanigorski, O Dean, T Crowley, S Jamain, L Gray, M Leboyer, M Berk, K Walder

(2019), Vol. 20, pp. 766-777, World Journal of Biological Psychiatry, London, Eng., C1

journal article
2018

Post-operative cognitive dysfunction: an exploration of the inflammatory hypothesis and novel therapies

D Skvarc, M Berk, L Byrne, O Dean, S Dodd, M Lewis, A Marriott, E Moore, G Morris, R Page, L Gray

(2018), Vol. 84, pp. 116-133, Neuroscience and biobehavioral reviews, Amsterdam, The Netherlands, C1

journal article

Mechanisms underpinning the polypharmacy effects of medications in psychiatry

Chiara Bortolasci, Briana Spolding, Edward Callaly, Sheree Martin, Bruna Panizzutti, Srisaiyini Kidnapillai, Timothy Connor, Kyoko Hasebe, Mohammadreza Mohebbi, Olivia Dean, Sean McGee, Seetal Dodd, Laura Gray, Michael Berk, Ken Walder

(2018), Vol. 21, pp. 582-591, The international journal of neuropsychopharmacology, Oxford, Eng., C1

journal article

Mediator effects of parameters of inflammation and neurogenesis from a N-acetyl cysteine clinical-trial for bipolar depression

Bruna Panizzutti, Chiara Bortolasci, Kyoko Hasebe, Srisaiyini Kidnapillai, Laura Gray, Ken Walder, Michael Berk, Mohammadreza Mohebbi, Seetal Dodd, Clarissa Gama, Pedro Magalhães, Susan Cotton, Flávio Kapczinski, Ashley Bush, Gin Malhi, Olivia Dean

(2018), Vol. 30, pp. 334-341, Acta neuropsychiatrica, Cambridge, Eng., C1

journal article
2017

Huntington's disease: pathogenic mechanisms and therapeutic targets

D Wright, T Renoir, L Gray, A Hannan

(2017), Vol. 15, pp. 93-128, Neurodegenerative diseases: pathology, mechanisms, and potential therapeutic targets, Cham, Switzerland, B1

book chapter

Adjunctive N-acetylcysteine in depression: exploration of interleukin-6, C-reactive protein and brain-derived neurotrophic factor

K Hasebe, L Gray, C Bortolasci, B Panizzutti, M Mohebbi, S Kidnapillai, B Spolding, K Walder, M Berk, G Malhi, S Dodd, O Dean

(2017), Vol. 29, pp. 337-346, Acta neuropsychiatrica, Cambridge, Eng., C1

journal article

the effect of n-acetylcysteine (nac) on human cognition - a systematic review

D Skvarc, O Dean, L Byrne, L Gray, S Lane, M Lewis, B Fernandes, M Berk, A Marriott

(2017), Vol. 78, pp. 44-56, Neuroscience & Biobehavioral Reviews, Amsterdam, The Netherlands, C1

journal article
2016

Affective dysfunction in a mouse model of Rett syndrome: therapeutic effects of environmental stimulation and physical activity

M Kondo, L Gray, G Pelka, S Leang, J Christodoulou, P Tam, A Hannan

(2016), Vol. 76, pp. 209-224, Developmental neurobiology, London, Eng., C1-1

journal article

N-acetylcysteine modulates glutamatergic dysfunction and depressive behavior in Huntington's disease

D Wright, L Gray, D Finkelstein, P Crouch, D Pow, T Pang, S Li, Z Smith, P Francis, T Renoir, A Hannan

(2016), Vol. 25, pp. 2923-2933, Human molecular genetics, Oxford, Eng., C1

journal article

The Post-Anaesthesia N-acetylcysteine Cognitive Evaluation (PANACEA) trial: study protocol for a randomised controlled trial

D Skvarc, O Dean, L Byrne, L Gray, K Ives, S Lane, M Lewis, C Osborne, R Page, D Stupart, A Turner, M Berk, A Marriott

(2016), Vol. 17, pp. 1-11, Trials, London, Eng., C1

journal article
2015

N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease

D Wright, T Renoir, Z Smith, A Frazier, P Francis, D Thorburn, S McGee, A Hannan, L Gray

(2015), Vol. 5, pp. 1-10, Translational psychiatry, New York, N. Y., C1

journal article

Early life environmental and pharmacological stressors result in persistent dysregulations of the serotonergic system

P Wong, S Ying, L Gray, C Roei Chang, S Cai, X Zhang

(2015), Vol. 9, pp. 1-13, Frontiers in behavioral neuroscience, Lausanne, Switzerland, C1-1

journal article
2014

Enhancing permanganate chemiluminescence detection for the determination of glutathione and glutathione disulfide in biological matrices

Z Smith, J Terry, N Barnett, L Gray, D Wright, P Francis

(2014), Vol. 139, pp. 2416-2422, Analyst, London, Eng., C1

journal article
2013

Chronic adrenocorticotrophic hormone treatment alters tricyclic antidepressant efficacy and prefrontal monoamine tissue levels

A Walker, S Burnett, K Hasebe, J McGillivray, L Gray, S McGee, K Walder, M Berk, S Tye

(2013), Vol. 242, pp. 76-83, Behavioural brain research, Amsterdam, The Netherlands, C1

journal article

The promise of N-acetylcysteine in neuropsychiatry

M Berk, G Malhi, L Gray, O Dean

(2013), Vol. 34, pp. 167-177, Trends in pharmacological sciences, Oxford, England, C1

journal article

Mind and body: how the health of the body impacts on neuropsychiatry

T Renoir, K Hasebe, L Gray

(2013), Vol. 4, pp. 1-16, Frontiers in pharmacology, Lausanne, Switzerland, C1-1

journal article
2012

Metabotropic glutamate receptors as targets for novel antipsychotic treatments.

L Gray, A Hannan, X Zhang

(2012), Vol. 13, pp. 1522-1534, Current pharmaceutical biotechnology, Amsterdam, The Netherlands, C1-1

journal article
2010

Region and diagnosis-specific changes in synaptic proteins in schizophrenia and bipolar I disorder

L Gray, B Dean, H Kronsbein, P Robinson, E Scarr

(2010), Vol. 178, pp. 374-380, Psychiatry research, Amsterdam, The Netherlands, C1-1

journal article
2009

Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-d-aspartic acid receptor up-regulation

L Gray, M van den Buuse, E Scarr, B Dean, A Hannan

(2009), Vol. 12, pp. 45-60, The international journal of neuropsychopharmacologyy, Oxford, Eng., C1

journal article

Sensitivity to MK-801 in phospholipase C-β1 knockout mice reveals a specific NMDA receptor deficit

L Gray, C McOmish, E Scarr, B Dean, A Hannan

(2009), Vol. 12, pp. 917-928, The international journal of neuropsychopharmacology, Oxford, England, C1-1

journal article
2008

Role of muscarinic receptors in the activity of N-desmethylclozapine: reversal of hyperactivity in the phospholipase C knockout mouse

L Gray, C McOmish, E Scarr, B Dean, A Hannan

(2008), Vol. 19, pp. 543-547, Behavioural pharmacology, Philadelphia, Pa., C1-1

journal article

Environmental enrichment ameliorates a motor coordination deficit in a mouse model of Rett syndrome Mecp2 gene dosage effects and BDNF expression

M Kondo, L Gray, G Pelka, J Christodoulou, P Tam, A Hannan

(2008), Vol. 27, pp. 3342-3350, European journal of neuroscience, London, Eng., C1-1

journal article
2007

Dissecting Cause and Effect in the Pathogenesis of Psychiatric Disorders: Genes, Environment and Behaviour

B Laura Gray, B Anthony J. Hannan

(2007), Vol. 7, pp. 470-478, Current Molecular Medicine, C1-1

journal article
2006

Serotonin 1a receptor and associated G-protein activation in schizophrenia and bipolar disorder

L Gray, E Scarr, B Dean

(2006), Vol. 143, pp. 111-120, Psychiatry research, Amsterdam, The Netherlands, C1-1

journal article

Regionally specific changes in levels of cortical S100β in bipolar 1 disorder but not schizophrenia

B Dean, L Gray, E Scarr

(2006), Vol. 40, pp. 217-224, Australian and New Zealand journal of psychiatry, London, Eng., C1-1

journal article

N-Ethylmaleimide sensitive factor in the cortex of subjects with schizophrenia and bipolar I disorder

L Gray, E Scarr, B Dean

(2006), Vol. 391, pp. 112-115, Neuroscience letters, Amsterdam, The Netherlands, C1-1

journal article

Increased levels of SNAP-25 and synaptophysin in the dorsolateral prefrontal cortex in bipolar I disorder

E Scarr, L Gray, D Keriakous, P Robinson, B Dean

(2006), Vol. 8, pp. 133-143, Bipolar disorders, London, Eng., C1-1

journal article
2004

A comparison of M1 and M4 muscarinic receptors in the thalamus from control subjects and subjects with schizophrenia

B Dean, L Gray, D Keriakous, E Scarr

(2004), Vol. 2, pp. 287-295, Thalamus & related systems, Amsterdam, The Netherlands, C1-1

journal article

Funded Projects at Deakin

Industry and Other Funding

Oxidative Stress in Mood Disorders

A/Prof Laura Gray

RLCMRF - Al And Val Rosenstrauss Medical Research Fellowship - Rebecca L. Cooper Medical Research Foundation

  • 2012: $19,815

Supervisions

Principal Supervisor
2017

Kyoko Hasebe

Thesis entitled: Investigating Neurobiological Mechanisms Linking Depression and Inflammation

Doctor of Philosophy (Medicine), School of Medicine

Associate Supervisor
2021

Lara Voglsanger

Thesis entitled: The relaxin-3 system in the mouse brain and gut

Master of Philosophy (Medicine), School of Medicine

2018

Srisaiyini Kidnapillai

Thesis entitled: Molecular Mechanisms of Action of Drugs Used to Treat Bipolar Disorder

Doctor of Philosophy (Medicine), School of Medicine