Profile image of Luba Sominsky

Dr Luba Sominsky

STAFF PROFILE

Position

Paediatric Research Fellow

Faculty

Faculty of Health

Department

School of Medicine

Campus

HERB

Contact

luba.sominsky@deakin.edu.au
+61 3 522 73077

Research interests

Neuroimmunology, Neuroendocrinology

Affiliations

Senior Scientist, Barwon Health

Publications

Filter by

2021

High maternal omega-3 supplementation dysregulates body weight and leptin in newborn male and female rats: implications for hypothalamic developmental programming

S Xavier, J Gili, P McGowan, S Younesi, P Wright, D Walker, S Spencer, L Sominsky

(2021), Vol. 13, pp. 1-19, Nutrients, Basel, Switzerland, C1

journal article

Microglial ablation in rats disrupts the circadian system

L Sominsky, T Dangel, S Malik, S De Luca, N Singewald, S Spencer

(2021), Vol. 35, pp. 1-10, FASEB Journal, Chichester, Eng., C1

journal article

Ovarian follicles are resistant to monocyte perturbations-implications for ovarian health with immune disruption

Luba Sominsky, Simin Younesi, Simone De Luca, Sophie Loone, Kylie Quinn, Sarah Spencer

(2021), pp. 1-13, Biology of reproduction, Oxford, Eng., C1

journal article

The maternal gut microbiome during pregnancy and offspring allergy and asthma

Yuan Gao, Ralph Nanan, Laurence Macia, Jian Tan, Luba Sominsky, Thomas Quinn, M O'Hely, Anne-Louise Ponsonby, Mimi Tang, Fiona Collier, Deborah Strickland, Poshmaal Dhar, Susanne Brix, Simon Phipps, Peter Sly, Sarath Ranganathan, Jakob Stokholm, Karsten Kristiansen, Lawrence Gray, Peter Vuillermin

(2021), pp. 1-31, Journal of Allergy and Clinical Immunology, Amsterdam, The Netherlands, C1

journal article

Monocyte perturbation modulates the ovarian response to an immune challenge

Simin Younesi, Sarah Spencer, Luba Sominsky

(2021), Vol. 536, pp. 1-8, Molecular and Cellular Endocrinology, Amsterdam, The Netherlands, C1

journal article

Maternal diet before and during pregnancy modulates microglial activation and neurogenesis in the postpartum rat brain

S Xavier, A Soch, S Younesi, S Malik, S Spencer, L Sominsky

(2021), Vol. 98, pp. 185-197, Brain, Behavior, and Immunity, C1

journal article
2020

Microglia depletion fails to abrogate inflammation-induced sickness in mice and rats

E Vichaya, S Malik, L Sominsky, B Ford, S Spencer, R Dantzer

(2020), Vol. 17, pp. 1-14, Journal of neuroinflammation, London, Eng., C1

journal article

The role of microglia in the second and third postnatal weeks of life in rat hippocampal development and memory

A Soch, L Sominsky, S Younesi, S De Luca, M Gunasekara, S Bozinovski, S Spencer

(2020), Vol. 88, pp. 675-687, Brain, behavior, and immunity, Amsterdam, The Netherlands, C1

journal article

Microglial regulation of satiety and cognition

S De Luca, A Miller, L Sominsky, S Spencer

(2020), Vol. 32, pp. 1-12, Journal of neuroendocrinology, Chichester, Eng., C1

journal article

Glial remodeling enhances short-term memory performance in Wistar rats

S De Luca, A Soch, L Sominsky, T Nguyen, A Bosakhar, S Spencer

(2020), Vol. 17, pp. 1-18, Journal of neuroinflammation, London, Eng., C1

journal article
2019

Obesity after neonatal overfeeding is independent of hypothalamic microgliosis

A Soch, L Sominsky, S De Luca, S Spencer

(2019), Vol. 31, pp. 1-12, Journal of neuroendocrinology, Chichester, Eng., C1

journal article

Chronic predator stress in female mice reduces primordial follicle numbers: implications for the role of ghrelin

M Di Natale, A Soch, I Ziko, S De Luca, S Spencer, L Sominsky

(2019), Vol. 241, pp. 201-219, Journal of endocrinology, Bristol, Eng., C1

journal article

Neuroimmune regulation of female reproduction in health and disease

E Fuller, S Younesi, S Xavier, L Sominsky

(2019), Vol. 28, pp. 8-13, Current opinion in behavioral sciences, Amsterdam, The Netherlands, C1

journal article

Conditional microglial depletion in rats leads to reversible anorexia and weight loss by disrupting gustatory circuitry

S De Luca, L Sominsky, A Soch, H Wang, I Ziko, M Rank, S Spencer

(2019), Vol. 77, pp. 77-91, Brain, behavior, and immunity, Amsterdam, The Netherlands, C1

journal article

High-fat diet worsens the impact of aging on microglial function and morphology in a region-specific manner

S Spencer, B Basri, L Sominsky, A Soch, M Ayala, P Reineck, B Gibson, R Barrientos

(2019), Vol. 74, pp. 121-134, Neurobiology of Aging, C1

journal article

Acylated ghrelin supports the ovarian transcriptome and follicles in the mouse: implications for fertility

L Sominsky, J Goularte, Z Andrews, S Spencer

(2019), Vol. 9, pp. 1-17, Frontiers in endocrinology, Lausanne, Switzerland, C1

journal article
2018

Acylated ghrelin suppresses the cytokine response to lipopolysaccharide and does so independently of the hypothalamic-pituitary-adrenal axis

I Ziko, L Sominsky, S De Luca, F Lelngei, S Spencer

(2018), Vol. 74, pp. 86-95, Brain, behavior, and immunity, Amsterdam, The Netherlands, C1

journal article

Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess serum amyloid A production

H Wang, M Blackall, L Sominsky, S Spencer, R Vlahos, M Churchill, S Bozinovski

(2018), Vol. 15, pp. 1-11, Journal of neuroinflammation, London, Eng., C1

journal article

Hormonal and nutritional regulation of postnatal hypothalamic development

L Sominsky, C Jasoni, H Twigg, S Spencer

(2018), Vol. 237, pp. R47-R64, Journal of endocrinology, Bristol, England, C1

journal article

Microglia: key players in neurodevelopment and neuronal plasticity

L Sominsky, S De Luca, S Spencer

(2018), Vol. 94, pp. 56-60, International journal of biochemistry and cell biology, Amsterdam, The Netherlands, C1

journal article

Neonatal overfeeding increases capacity for catecholamine biosynthesis from the adrenal gland acutely and long-term in the male rat

L Sominsky, L Ong, I Ziko, P Dickson, S Spencer

(2018), Vol. 470, pp. 295-303, Molecular and cellular endocrinology, Amsterdam, The Netherlands, C1

journal article

How Food Can Change a Baby's Brain

Luba Sominsky, Sarah Spencer

(2018), Vol. 6, pp. 1-1, Frontiers for Young Minds, Lausanne, Switzerland, C1

journal article
2017

Neonatal immune activation depletes the ovarian follicle reserve and alters ovarian acute inflammatory mediators in neonatal rats

E Fuller, L Sominsky, J Sutherland, K Redgrove, L Harms, E McLaughlin, D Hodgson

(2017), Vol. 97, pp. 719-730, Biology of reproduction, Oxford, Eng., C1

journal article

Neonatal overfeeding by small-litter rearing sensitises hippocampal microglial responses to immune challenge: Reversal with neonatal repeated injections of saline or minocycline

S De Luca, I Ziko, K Dhuna, L Sominsky, M Tolcos, L Stokes, S Spencer

(2017), Vol. 29, pp. 1-14, Journal of neuroendocrinology, Chichester, Eng., C1

journal article

Neonatal overfeeding disrupts pituitary ghrelin signalling in female rats long-term; implications for the stress response

L Sominsky, I Ziko, S Spencer

(2017), Vol. 12, pp. 1-18, PLoS ONE, San Francisco, Calif., C1

journal article

Early life disruption to the ghrelin system with over-eating is resolved in adulthood in male rats

L Sominsky, I Ziko, T Nguyen, Z Andrews, S Spencer

(2017), Vol. 113, pp. 21-30, Neuropharmacology, Amsterdam, The Netherlands, C1

journal article

Linking stress and infertility: a novel role for Ghrelin

L Sominsky, D Hodgson, E McLaughlin, R Smith, H Wall, S Spencer

(2017), Vol. 38, pp. 432-467, Endocrine reviews, Oxford, Eng., C1

journal article

Hyperleptinemia in neonatally overfed female rats does not dysregulate feeding circuitry

I Ziko, L Sominsky, T Nguyen, K Yam, S Luca, A Korosi, S Spencer

(2017), Vol. 8, pp. 1-11, Frontiers in endocrinology, Lausanne, Switzerland, C1

journal article

Hypothalamic effects of neonatal diet: reversible and only partially leptin dependent

L Sominsky, I Ziko, T Nguyen, J Quach, S Spencer

(2017), Vol. 234, pp. 41-56, The journal of endocrinology, Bristol, Eng., C1

journal article

Early life peripheral lipopolysaccharide challenge reprograms catecholaminergic neurons

L Ong, E Fuller, L Sominsky, D Hodgson, P Dunkley, P Dickson

(2017), Vol. 7, pp. 1-6, Scientific reports, London, Eng., C1

journal article
2016

Overfeeding during a critical postnatal period exacerbates hypothalamic-pituitary-adrenal axis responses to immune challenge: a role for adrenal melanocortin 2 receptors

Guohui Cai, Ilvana Ziko, Joanne Barwood, Alita Soch, Luba Sominsky, Juan Molero, Sarah Spencer

(2016), Vol. 6, pp. 1-10, Scientific reports, London, Eng., C1

journal article

Early life overfeeding impairs spatial memory performance by reducing microglial sensitivity to learning

S De Luca, I Ziko, L Sominsky, J Nguyen, T Dinan, A Miller, T Jenkins, S Spencer

(2016), Vol. 13, pp. 1-15, Journal of neuroinflammation, London, Eng., C1

journal article

Neonatal overfeeding induces early decline of the ovarian reserve: implications for the role of leptin

L Sominsky, I Ziko, A Soch, J Smith, S Spencer

(2016), Vol. 431, pp. 24-35, Molecular and cellular endocrinology, Amsterdam, The Netherlands, C1

journal article

Effects of exercise on adolescent and adult hypothalamic and hippocampal neuroinflammation

A Soch, S Bradburn, L Sominsky, S De Luca, C Murgatroyd, S Spencer

(2016), Vol. 26, pp. 1435-1446, Hippocampus, Chichester, Eng., C1

journal article

Delayed Spatial Win-shift Test on Radial Arm Maze

Simone De Luca, Luba Sominsky, Sarah Spencer

(2016), Vol. 6, Bio-Protocol, Sunnyvale, Calif., C1

journal article
2015

Oral immune activation by disgust and disease-related pictures

R Stevenson, D Hodgson, M Oaten, L Sominsky, M Mahmut, T Case

(2015), Vol. 29, pp. 119-129, Journal of psychophysiology, Boston, Mass., C1

journal article

Factors in early-life programming of reproductive fitness

L Sominsky, E Fuller, D Hodgson

(2015), Vol. 102, pp. 216-225, Neuroendocrinology, Sydney, N.S.W., E1

conference
2014

Eating behavior and stress: A pathway to obesity

L Sominsky, S Spencer

(2014), Vol. 5, Frontiers in Psychology, C1-1

journal article

Neonatal overfeeding alters hypothalamic microglial profiles and central responses to immune challenge long-term

I Ziko, S De Luca, T Dinan, J Barwood, L Sominsky, G Cai, R Kenny, L Stokes, T Jenkins, S Spencer

(2014), Vol. 41, pp. 32-43, Brain, Behavior, and Immunity, C1-1

journal article

Plasma IL-12 levels are suppressed in vivo by stress and surgery through endogenous release of glucocorticoids and prostaglandins but not catecholamines or opioids

L Shaashua, E Rosenne, E Neeman, L Sorski, L Sominsky, P Matzner, G Page, S Ben-Eliyahu

(2014), Vol. 42, pp. 11-23, Psychoneuroendocrinology, C1-1

journal article
2013

Immune regulation of ovarian development: Programming by neonatal immune challenge

L Sominsky, A Sobinoff, M Jobling, V Pye, E McLaughlin, D Hodgson

(2013), Frontiers in Neuroscience, C1-1

journal article

Neonatal lipopolysaccharide treatment has long-term effects on monoaminergic and cannabinoid receptors in the rat

K Zavitsanou, V Dalton, A Walker, C Weickert, L Sominsky, D Hodgson

(2013), Vol. 67, pp. 290-299, Synapse, C1-1

journal article

Functional Programming of the Autonomic Nervous System by Early Life Immune Exposure: Implications for Anxiety

L Sominsky, E Fuller, E Bondarenko, L Ong, L Averell, E Nalivaiko, P Dunkley, P Dickson, D Hodgson

(2013), Vol. 8, PLoS ONE, C1-1

journal article
2012

In vivo suppression of plasma IL-12 levels by acute and chronic stress paradigms: Potential mediating mechanisms and sex differences

L Shaashua, L Sominsky, B Levi, L Sorski, M Reznick, G Page, S Ben-Eliyahu

(2012), Vol. 26, pp. 996-1005, Brain, Behavior, and Immunity, C1-1

journal article

Neonatal immune challenge alters reproductive development in the female rat

L Sominsky, C Meehan, A Walker, L Bobrovskaya, E McLaughlin, D Hodgson

(2012), Vol. 62, pp. 345-355, Hormones and Behavior, C1-1

journal article

The sustained phase of tyrosine hydroxylase activation in vivo

L Ong, L Sominsky, P Dickson, D Hodgson, P Dunkley

(2012), Vol. 37, pp. 1938-1943, Neurochemical Research, C1-1

journal article

Transgenerational transmission of anxiety induced by neonatal exposure to lipopolysaccharide: Implications for male and female germ lines

A Walker, G Hawkins, L Sominsky, D Hodgson

(2012), Vol. 37, pp. 1320-1335, Psychoneuroendocrinology, C1-1

journal article

Increased microglial activation in the rat brain following neonatal exposure to a bacterial mimetic

L Sominsky, A Walker, L Ong, R Tynan, F Walker, D Hodgson

(2012), Vol. 226, pp. 351-356, Behavioural Brain Research, C1-1

journal article
2011

Maternal separation in early life impairs tumor immunity in adulthood in the F344 rat

T Nakamura, A Walker, L Sominsky, T Allen, S Rosengren, D Hodgson

(2011), Vol. 14, pp. 335-343, Stress, C1-1

journal article

Neonatal lipopolysaccharide exposure impairs sexual development and reproductive success in the Wistar rat

A Walker, S Hiles, L Sominsky, E McLaughlin, D Hodgson

(2011), Vol. 25, pp. 674-684, Brain, Behavior, and Immunity, C1-1

journal article
2009

Metastatic-promoting effects of LPS: Sexual dimorphism and mediation by catecholamines and prostaglandins

R Naor, V Domankevich, S Shemer, L Sominsky, E Rosenne, B Levi, S Ben-Eliyahu

(2009), Vol. 23, pp. 611-621, Brain, Behavior, and Immunity, C1-1

journal article

Reducing resistance to diabetes treatment using short narrative interventions

M Mishalia, L Sominskya, A Heymann

(2009), Vol. 27, pp. 192-197, Family Practice, C1-1

journal article
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Predicting Health: The Role of the Early-Life Environment

Luba Sominsky, Adam Walker, Deborah Hodgson

(), pp. 266-295, The Wiley-Blackwell Handbook of Psychoneuroimmunology, B1-1

book chapter

Funded Projects at Deakin

No Funded Projects at Deakin found

Supervisions

No completed student supervisions to report